Archive for the 'Disease/Health Effects' Category
06
Mar
(Beyond Pesticides, March 6, 2012) New research conducted in New Bedford, Massachusetts suggests that organochlorine chemicals, which were first linked to learning problems in children more than two decades ago, may play a role in attention-deficit hyperactivity disorder (ADHD), especially in boys. Previous research has reported associations between organochlorines and ADHD-related behaviors, but this research found sex-specific effects in children born to mothers who lived near the contaminated harbor and dumpsites in low-income communities. This study adds to a growing body of literature associating learning disorders with prenatal chemical exposures. According to the study, Neuropsychological Measures of Attention and Impulse Control among 8-Year-Old Children Exposed Prenatally to Organochlorines, boys who were exposed to higher levels of the organochlorines -polychlorinated biphenyls (PCBs) and DDE (a metabolite of DDT)- in the womb scored lower on focus and concentration tests, which indicates they are more likely to have attention problems often related to ADHD. In the study, umbilical cord blood was collected from 788 newborns born between 1993 and 1998 from four towns near New Bedford Harbor, Mass., to see what they were exposed to in the womb. Roughly eight years after they were born, almost 600 of these children underwent two tests. […]
Posted in ADHD | No Comments »
13
Feb
(Beyond Pesticides, February 13, 2012) Acclaimed ecologist and Living Downstream author, Sandra Steingraber, will be speaking at the 30th National Pesticide Forum. With Connecticut and communities throughout the country facing threats to existing environmental laws, as well as opportunities for greater protection and increased local control, this conference will have a strong focus on organic land management and protective policies. Join Dr. Steingraber and other researchers, authors, beekeepers, organic business leaders, elected officials, activists, and others to discuss the latest science, policy solutions, and grassroots action. Registration Register online. Fees start at $35 ($15 for students) and include all sessions, conference materials, and organic food and drink. Speaker Highlights Sandra Steingraber, PhD – An acclaimed ecologist and author, Dr. Steingraber explores the links between human rights and the environment, with a focus on chemical contamination. She takes a personal and scientific look at these issues and offers insights into how we can protect our environment and ourselves. She brings a clear, lyrical voice to the complex evidence of biology. The author of several books, including her latest, Raising Elijah, Dr. Steingraber has been called “a poet with a knife” by Sojourner magazine, and received many honors for her work as […]
Posted in Alternatives/Organics, Disease/Health Effects, Events, Lawns/Landscapes, Pollinators | No Comments »
01
Feb
(Beyond Pesticides, February 1, 2012) Pesticides could be suppressing vitamin D levels in people, leading to deficiency and disease, say scientists. This comes from a new study which discovered that adults with high serum concentrations of organochlorine pesticides, such as DDT, have lower vitamin D levels, further proving that these chemicals have a long-lasting impact on human health. While not widely appreciated, some organochlorine pesticides continue to be used in the U.S., resulting in exposure through our diet, environment, and prescription drugs, while most organochlorine pesticides have been banned in the U.S. and much of the world. Exposure to low doses of organochlorine pesticides has been previously linked to common diseases like type 2 diabetes, metabolic syndrome and cardiovascular disease. Vitamin D deficiency has similarly been associated with a rise in chronic diseases, but the two have been studied separately by researchers in different fields. The study, “Associations between Organochlorine Pesticides and Vitamin D Deficiency in the U.S. Population,” compared serum concentrations of organochlorine (OC) pesticides with serum concentrations of 25-hydroxyvitamin D (25(OH)D), a vitamin D pre-hormone, which is used to assess vitamin D levels in the body. It concludes that background exposure to some OC pesticides can lead to […]
Posted in DDT, Disease/Health Effects | No Comments »
31
Jan
(Beyond Pesticides, January 31, 2012) The Environmental Protection Agency (EPA) has proposed an expansion in pyrethrins/pyrethroid insecticide uses as part of its cumulative risk assessment for this neurotoxic class of chemicals. In the cumulative risk assessment, EPA concludes that pyrethroids “do not pose risk concerns for children or adults,” ignoring a wealth of independent data that links this class of chemicals to certain cancers, respiratory and reproductive problems, and the onset of insect resistance. It went as far as to state that its cumulative assessment supports consideration of registering additional new uses of these pesticides, potentially opening the flood gates for manufacturers to bombard the market with more pyrethroid pesticides, endangering the health of the public. The agency is accepting public comments through February 8, 2012. Tell EPA that it has ignored numerous health effects and that these pesticides do pose unacceptable risks to human health given the availability of alternatives. Submit comments directly to the EPA docket or sign-on to Beyond Pesticides’ comments. In its comments to EPA, Beyond Pesticides states: There are several major concerns and flaws plaguing this cumulative assessment, which therefore does not meet the regulatory burden in fully evaluating synthetic pyrethroids’ effect on public and […]
Posted in Bifenthrin, Chemicals, Children/Schools, Disease/Health Effects, Permethrin, Pesticide Regulation, Pyrethrin | 6 Comments »
19
Jan
(Beyond Pesticides, January 19, 2012) Although organic farming and land management continue to grow, policies to protect people from pesticides are threatened in the Northeast and around the country. At the same time, cutting-edge science links pesticide exposure to health problems, honey bee colony collapse, and other environmental issues. Join researchers, authors, beekeepers, organic business leaders, elected officials, activists, and others at Beyond Pesticides’ 30th National Pesticide Forum to discuss the latest science, policy solutions, and grassroots action. This national conference, Healthy Communities: Green solutions for safe environments, will be held March 30-31 at Yale University in New Haven, CT. Registration Register online. Fees start at $35 ($15 for students) and include all sessions, conference materials, and organic food and drink. Speakers Confirmed speaker highlights include: Gary Hirshberg is chairman and co-founder of Stonyfield Farm, the world’s leading organic yogurt producer, and the author of Stirring It Up: How to Make Money and Save the World. Previously, he directed the Rural Education Center, the small organic farming school from which Stonyfield was spawned. Before that, Gary had served as executive director of The New Alchemy Institute, a research and education center dedicated to organic farming, aquaculture and renewable energy. He […]
Posted in Alternatives/Organics, Children/Schools, Connecticut, Disease/Health Effects, Events, Lawns/Landscapes, Pollinators, Water | 3 Comments »
09
Dec
(Beyond Pesticides, December 9, 2011) A recent study published in the journal NeuroToxicology has found a positive link between exposure to the pesticide propoxur and poor motor development in infants. At the age of two, children exposed to propoxur in the womb experience poor development of motor skills, according to a test of mental development. The study joins numerous others that consistently show birth defects and developmental problems when fetuses and infants are exposed to pesticides. The study, undertaken by researchers at Wayne State University in Michigan, the University of the Philippines, and Davao Regional Hospital in the Philippines, is entitled “Fetal exposure to propoxur and abnormal child neurodevelopment at 2 years of age.” It examines levels of exposure to multiple pesticides in pregnant women living in areas of high pesticide use in the Philippines. Pesticide exposure was monitored by measuring the pesticide content of hair and blood for both mothers and children. The researchers then compare these exposure levels to adverse outcomes regarding the health of the infants once they were born. To accomplish this, the team used a method called path analysis modeling in order to determine what effects the pesticides might have on fetal development. The striking […]
Posted in Bedbugs, Birth defects, Propoxur | No Comments »
05
Dec
(Beyond Pesticides, December 5, 2011) On December 3, the 27th anniversary of the Bhopal pesticide plant disaster in Bhopal, India, a trial began in an international people’s court in India involving the world’s six largest pesticide companies: Monsanto, Syngenta, Bayer, BASF, Dow and Dupont. These companies, collectively known as the “Big 6,” are cited by prosecutors for their human rights violations, including internationally recognized rights to life, livelihood and health. Beyond Pesticides joined Pesticide Action Network (PAN) and others in signing a joint statement demanding that these companies be held accountable for their human rights violations, which was presented at the trial. The trial, hosted by PAN International, is facilitated by the Permanent People’s Tribunal (PTT), an international opinion tribunal independent from State authorities. The prosecution’s 230-page indictment outlines the global threats to human rights. It begins: The victims and survivors of [pesticide industry] aggression are the poor peasants, small-scale farmers, agricultural workers, rural women, children, and indigenous and agricultural communities around the world. They are at the mercy of the expanding power of the agrochemical [corporations] and are losing their control over their seeds and knowledge, and suffering debilitating physical and chronic effects due to pesticide poisoning, including coping […]
Posted in Agriculture, BASF, Bayer, Corporations, Disease/Health Effects, Dow Chemical, DuPont, Environmental Justice, Farmworkers, International, Monsanto, Syngenta | 2 Comments »
29
Nov
(Beyond Pesticides, November 29, 2011) New research shows that women who drink water containing the widely used herbicide atrazine may be more likely to have irregular menstrual cycles and low estrogen levels, even at concentrations far below federal drinking water standards considered safe by the U.S. Environmental Protection Agency (EPA). Researchers compared women living in Illinois farm towns where atrazine is used regularly to women living in Vermont where the herbicide is used sparingly, and found that the women in Illinois were almost five times more likely to report irregular menstrual cycles, including more than six weeks between periods. Consumption of over two cups of unfiltered Illinois water daily was associated with increased risk of irregular periods. The study, entitled “Menstrual cycle characteristics and reproductive hormone levels in women exposed to atrazine in drinking water,” was published in the journal Environmental Research earlier this month, and is based on municipal tap water tested between July and September of 2005. In the study, participants maintained menstrual cycle diaries, answered a questionnaire, and provided daily urine samples for analyses of luteinizing hormone and estradiol and progesterone metabolites. To measure exposure, analysts looked at the state of residence, concentrations of atrazine and chlorotriazine […]
Posted in Atrazine, Illinois, Reproductive Health, Vermont | No Comments »
15
Nov
(Beyond Pesticides, November 15, 2011) Research published in the online edition of Environmental Health Perspectives finds that exposure to certain pesticides elevates the risk of non-Hodgkin’s Lymphoma (NHL). The study, “A Prospective Study of Organochlorines in Adipose Tissue and Risk of non-Hodgkin’s Lymphoma,” finds a positive correlation between levels of the organochlorine pesticides DDT, cis-nonachlor, chlordane, and their breakdown products in human fat tissue and the often deadly form of cancer. The researchers from the Danish Cancer Society’s Institute of Cancer Epidemiology conducted a case-cohort study using a prospective Danish cohort of 57,053 persons enrolled between 1993 and 1997. Within the cohort they identified 256 persons diagnosed with NHL in the population-based nationwide Danish Cancer Registry and randomly selected 256 sub-cohort persons. The research team measured concentrations of eight pesticides and ten polychlorinated biphenyl congeners (PCBs) in fat tissue collected upon enrollment. The results indicate a higher risk of NHL in association with higher fat tissue levels of DDT, cis-nonachlor and oxychlordane, but shows no association with PCBs. Because the tissue samples were taken up to 15 years prior to the cancer diagnosis, the research suggests that exposure to these organochlorines increases the risk of NHL later in life and […]
Posted in Cancer, Chemicals, Chlordane, DDT, Disease/Health Effects, non-Hodgkin's Lymphoma | 1 Comment »
08
Nov
(Beyond Pesticides, November 8, 2011) The Environmental Protection Agency (EPA) published a petition to ban the endocrine (hormone) disrupting herbicide atrazine on September 14, 2011, opening a 60-day comment period for the public to weigh-in on the issue that ends Friday. Tell EPA that because atrazine poses unacceptable risks to humans and wildlife, the agency should remove this hazardous pesticide from the market immediately. Submit comments directly to EPA’s atrazine petition docket by November 14, 2011 or sign your organization or business onto Beyond Pesticides’ comments by Friday, November 11. According to its Federal Register notice, EPA received a petition from the non-profit organization Save the Frogs that includes over 10,000 signatures and select statements from the public, as well as two brief summaries of published literature, one by Jason Rohr, PhD (University of South Florida), and one by Tyrone Hayes, PhD (University of California, Berkeley), that is co-authored by 39 other scientists. In conjunction with the petition, EPA received nearly 50,000 emails from supporters of the Center for Biological Diversity and the Natural Resources Defense Council requesting that EPA “immediately take steps to phase out atrazine use in the United States,” stating that atrazine poses an unreasonable risk to […]
Posted in Atrazine, Chemicals, Disease/Health Effects, Endocrine Disruption, Syngenta, Take Action, Water, Wildlife/Endangered Sp. | No Comments »
14
Oct
(Beyond Pesticides, October 14, 2011) Researchers at Uppsala University in Sweden have found that environmental toxicants such as dioxins, PCBs, and pesticides can pose a risk for cardiovascular disease. The results of the study, entitled “Circulating Levels of Persistent Organic Pollutants (POPs) and Carotid Atherosclerosis in the Elderly,” show a link between exposure to persistent organic pollutants (POPs), including several organochlorine pesticides, and the development of atherosclerosis, which can lead to heart disease. The study will be published in the journal Environmental Health Perspectives, and a version of it is available online ahead of print. Cardiovascular diseases, including heart attacks and strokes, are the most common cause of death in industrialized countries, and the most important underlying cause of these diseases is atherosclerosis. Unbalanced blood fats, diabetes, smoking, and high blood pressure are traditionally recognized risk factors for atherosclerosis. Previous studies have also reported possible links between cardiovascular disease and high levels of persistent (long-lived and hard-to-degrade) organic environmental toxicants, such as dioxins, polychlorinated biphenyls (PCBs), and pesticides. These compounds are fat-soluble and can therefore accumulate in vessel walls. However, no earlier studies have investigated possible links between exposure to these compounds and atherosclerosis. Of the POPs that were screened […]
Posted in Biomonitoring, Cardiovascular Disease, Chlordane, DDT, hexachlorobenzene (HCB) | No Comments »
26
Sep
(Beyond Pesticides, September 26, 2011) On September 23, 2011, the Centers for Disease Control and Prevention (CDC) published a study in its Morbidity and Mortality Weekly Report linking pesticides sprayed in attempts to control bed bugs to poisoning incidents and death. Because bed bugs do not transmit disease and can be controlled without pesticides, this risk is completely unnecessary. The study, “Acute Illnesses Associated with Insecticides Used to Control Bed Bugs,” utilized data from California, Florida, Michigan, North Carolina, New York, Texas, and Washington. In those seven states, over 100 poisonings, including one fatality, were associated with bed bug-related insecticide use. The CDC researchers used data from states participating in the Sentinel Event Notification System for Occupational Risks (SENSOR)-Pesticides program and the New York City Department of Health and Mental Hygiene (NYC DOHMH). The authors defined “acute illness” associated with an insecticide used to control bed bugs as two or more acute adverse health effects resulting from exposure to an insecticide used for bed bug control. The study reports: A total of 111 illnesses associated with bed bug–related insecticide use were identified; although 90 (81%) were low severity, one fatality occurred. Pyrethroids, pyrethrins, or both were implicated in 99 (89%) […]
Posted in Bedbugs, Chemicals, Disease/Health Effects, Permethrin | No Comments »
20
Sep
(Beyond Pesticides, September 20, 2011) A study supported by the U.S. Army Medical Research and Materiel Command links pesticide exposure and other factors to Gulf War illness (also referred to as Gulf War Syndrome), an illness characterized by a wide range of acute and chronic symptoms experienced by veterans and civilians after the 1991 Gulf War. The study, “Complex Factors in the Etiology of Gulf War Illness: Wartime Exposures and Risk Factors in Veteran Subgroups,” is published in the September 19, 2011 online edition of Environmental Health Perspectives. The researchers designed the study to compare the characteristics of deployment and the risk factors experienced by veterans participating in various theaters of the Gulf War. Among personnel who were in Iraq or Kuwait, where all battles took place, four exposures were independently associated with GWI: taking PB pills, being within one mile of an exploding SCUD missile, using pesticides on the skin, and exposure to smoke from oil well fires. For veterans who remained in support areas, GWI was significantly associated only with personal pesticide use, with increased prevalence (OR=12.7, CI=2.6-61.5) in the relatively small subgroup who wore pesticide-treated uniforms, nearly all of whom also used skin pesticides. Among 64 pesticide […]
Posted in DEET, Gulf War Syndrome, Lindane, Permethrin | 1 Comment »
30
Aug
(Beyond Pesticides, August 30, 2011) A new study finds that older men living in California’s Central Valley are more likely to develop prostate cancer if they were exposed to certain agricultural pesticides than those who were not exposed. The study examines exposure via drift rather than occupational exposure, although similar results have been noted in farmworker populations. Exposure to methyl bromide or various organochlorine pesticides increased the risk of cancer by about one and a half times. The study, “Prostate cancer and ambient pesticide exposure in agriculturally intensive areas in California,” was published in the June 2011 issue of the American Journal of Epidemiology. The researchers from the University of Southern California’s Keck School of Medicine recruited 173 men between the ages of 60 to 74 from 670 identified by the California Cancer Registry as being diagnosed with prostate cancer between August 2005 and July 2006 in California’s Central Valley. The authors used calendars and questionnaires to determine where they lived and worked between 1974 and 1999, and compared this to historical data of the corresponding area’s agricultural pesticide use from state pesticide use reports and land use records. In comparison with unexposed persons, increased risks of prostate cancer were […]
Posted in Chemicals, methyl bromide, Prostate Cancer | No Comments »
11
Aug
(Beyond Pesticides, August 11, 2011) A combination of eleven different kinds of commonly used pyrethroids were tested on mice in a new study which found that, at real-world exposure levels, the insecticides can produce heightened toxicity that is equal to the sum of each insecticide’s individual effect. The mixture of similar-acting insecticides works by over-stimulating electronic channels in the mouse’s brain cells and eventually causing death. This study adds to the growing body of research on the toxicity of pesticide combinations in nature and showcases the need for policy change because the current risk assessment approach to regulating pesticides fails to look at chemical mixtures and synergistic effects. The U.S. Environmental Protection Agency (EPA) currently regulates on a chemical-by-chemical basis, but as this study demonstrates, interacting chemicals can have synergistic effects at very low levels, where a “chemical cocktail” of multiple interacting chemicals combine to have greater effects than expected. Pesticides can also have a cumulative “toxic loading” effect both in the immediate and long term. Researchers exposed mice brain cells to eleven different food-use pyrethroid insecticides either singly or in a mixture in the study entitled ”Additivity of pyrethroid actions on sodium influx in cerebrocortical neurons in primary culture.” […]
Posted in Bifenthrin, Cyfluthrin, cypermethrin, Deltamethrin, esfenvalerate, Nervous System Effects, Permethrin | No Comments »
02
Aug
(Beyond Pesticides, August 2, 2011) Under pressure from lab results showing arsenic in apple juice, the U.S. Food and Drug Administration (FDA) and New York state officials inspected a Williamson, NY Mott’s apple products plant for the toxic metal on July 26, 2011. While the lab tests commissioned by the Rochester-based Empire State Consumer Project examined several brands of apple juice and apple sauce, Mott’s Apple Juice stood out, with one sample registering 55 parts per billion of arsenic, five times higher than the Environmental Protection Agency’s (EPA) legal limit (tolerance level) for drinking water. While no longer used in U.S. orchards, arsenic-based pesticides are still used on food crops in some countries, including China. “This is not the first time high levels of arsenic have been found in apple juice,” said Judy Braiman, executive director of the Empire State Consumer Project. “It is past time for the FDA to set a limit on a toxic substance like arsenic with long term health effects in the juice that kids drink.” Two-thirds of apple juice that Americans consume ””more than 400 million gallons annually”” comes from China. The Empire State Consumer Project and Food & Water Watch sent a letter to […]
Posted in Agriculture, Disease/Health Effects, MSMA, New York | 1 Comment »
25
Jul
(Beyond Pesticides, July 25, 2011) Exposure to certain pesticides and polycyclic aromatic hydrocarbons (PAHs) in the womb has been linked to neural tube defects, which lead to conditions such as spina bifida, according to researchers at Peking University in China. The study finds elevated levels of the organochlorine pesticides DDT, alpha-hexachlorocyclohexane (a lindane contaminant) and endosulfan, as well as PAHs in the placentas of women who had babies or aborted fetuses with such birth defects. The study, “Association of selected persistent organic pollutants in the placenta with the risk of neural tube defects,” was published July 8, 2011 in the online edition of the Proceedings of the National Academy of Sciences. While most organochlorine pesticides are banned or restricted, they still continue to cause problems decades after their widespread use has ended. This study reinforces the need for a more precautionary approach to regulating pesticides and industrial chemicals. Once released into the environment, many chemicals can affect health for generations, either through persistence or genetic means. PAHs are a group of over 100 different chemicals that are formed during the incomplete burning of coal, oil and gas, garbage, or other organic substances like tobacco or charbroiled meat. PAHs are usually […]
Posted in Birth defects, Chemicals, DDT, Disease/Health Effects, Endosulfan, Lindane | No Comments »
22
Jul
(Beyond Pesticides, July 22, 2011) Parallel bills have been introduced in the U.S. Senate and U.S. House of Representatives designed to increase federal research on endocrine disrupting chemicals and ensure public safety by restricting or eliminating chemicals found to present unacceptable risks to public health. S 1361, introduced by Senator John Kerry (D-MA), and HR 2521, introduced by Rep. Jim Moran (D-VA), are both titled the Endocrine-Disrupting Chemicals Exposure Elimination Act. The bills would establish a scientific panel at the National Institute of Environmental Health Sciences (NIEHS) to evaluate up to ten chemicals per year that potentially affect the endocrine system and would create a trigger to ban those found most harmful to public health. The bills would create a more updated scientific evaluation process than any that currently exists in the federal government for reviewing potential endocrine disruptors and would have a strong regulatory mandate to ban or restrict chemicals that are found to present serious health risks. The specific process outlined directs the National Toxicology Program at NIEHS to evaluate each chemical according to (i) the amount of evidence that it is an endocrine disruptor, (ii) the “level of concern” that it may disrupt hormones, and (iii) the […]
Posted in Disease/Health Effects, Endocrine Disruption, National Politics, Pesticide Regulation | 2 Comments »
21
Jul
(Beyond Pesticides, July 22, 2011) Parallel bills have been introduced in the U.S. Senate and U.S. House of Representatives designed to increase federal research on endocrine disrupting chemicals and ensure public safety by restricting or eliminating chemicals found to present unacceptable risks to public health. S. 1361, introduced by Senator John Kerry (D-MA), and H.R. 2521, introduced by Rep. Jim Moran (D-VA), are both titled the Endocrine-Disrupting Chemicals Exposure Elimination Act. The bills would establish a scientific panel at the National Institute of Environmental Health Sciences (NIEHS) to evaluate up to ten chemicals per year that potentially affect the endocrine system and would create a trigger to ban those found most harmful to public health. The bills would create a more updated scientific evaluation process than any that currently exists in the federal government for reviewing potential endocrine disruptors and would have a strong regulatory mandate to ban or restrict chemicals that are found to present serious health risks. The specific process outlined directs the National Toxicology Program at NIEHS to evaluate each chemical according to (i) the amount of evidence that it is an endocrine disruptor, (ii) the “level of concern” that it may disrupt hormones, and (iii) the […]
Posted in Endocrine Disruption, National Politics, Pesticide Regulation | No Comments »
11
Jul
(Beyond Pesticides, July 11, 2011) The findings of a research team suggest that the concentrations of the banned but still persistent insecticide chlordane and the widely used insecticide permethrin in cord blood may be associated with inflammatory cytokines (signaling molecules of the nervous and immune system important to intercellular communication) in the fetus. The results from the research team were significant because few studies on the developmental effects of chlordane and permethrin in humans have been performed, and they were the first to demonstrate an association between in utero exposures with changes in the immune systems of newborns. The data and findings are found in this month’s Research Brief by the National Institute of Environmental Health Sciences (NIEHS) Superfund Research Program, which highlights the widespread aggregate pesticide exposure that individuals in the U.S. experience, focusing on a recent study on the developmental effects of chlordane and permethrin mixtures. The study looks at the relationship between cord serum concentrations of chlordane and permethrin pesticides, gestational age, size at birth and the presence of inflammatory cytokines, which are endogenous proteins secreted as signaling compounds to coordinate immune system functions. The study, entitled “Fetal Exposure to Chlordane and Permethrin Mixtures in Relation to […]
Posted in Chlordane, Disease/Health Effects, Permethrin, Piperonyl butoxide (PBO) | No Comments »
05
Jul
(Beyond Pesticides, July 5, 2011) Recent findings add to a growing body of evidence that persistent organic pollutants (POPs) might drive changes in the body that lead to diabetes, researchers say. A new study finds that environmental exposure to some POPs substantially increased risk of future type 2 diabetes in an elderly population. POPs are lipophilic (fat-loving) chemicals that accumulate mainly in adipose tissue and have recently been linked to type 2 diabetes. This current study, “Polychlorinated Biphenyls and Organochlorine Pesticides in Plasma Predict Development of Type 2 Diabetes in the Elderly: The Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) Study,” sought to follow up on previous findings that had linked these chemicals with type 2 diabetes and was performed to evaluate prospective associations of type 2 diabetes with selected POPs among the elderly. The team recruited a group of 725 diabetes-free elderly adults in Sweden and took blood samples to measure their levels of the pollutants. Then, the researchers followed them for the next five years. Thirty-six of the study participants were diagnosed with type 2 diabetes over that time. Nineteen POPs (14 polychlorinated biphenyl [PCB] congeners, 3 organochlorine pesticides1 brominated diphenyl ether, and 1 dioxin) were […]
Posted in Diabetes | No Comments »
28
Jun
(Beyond Pesticides, June 28, 2011) Recent studies have linked Parkinson’s disease to pesticide exposure. In a new article published in the journal Molecular Neurodegeneration, researchers at the University of Missouri School of Medicine take some of the first steps toward understanding this link and unraveling the molecular dysfunction that occurs when proteins are exposed to environmental toxins. The study, “Oxidation of the cysteine-rich regions of parkin perturbs its E3 ligase activity and contributes to protein aggregation,” helps further explain recent NIH findings that demonstrate the link between Parkinson’s disease and two particular pesticides — rotenone and paraquat. “Fewer than 5 percent of Parkinson’s cases are attributed to genetics, but more than 95 percent of cases have unknown causes,” said Zezong Gu, MD, PhD, assistant professor of pathology and anatomical sciences. “This study provides the evidence that oxidative stress, possibly due to sustained exposure to environmental toxins, may serve as a primary cause of Parkinson’s. This helps us begin to unveil why many people, such as farmers exposed to pesticides, have an increased incidence of the disease.” Scientists previously understood that Parkinson’s is associated with oxidative stress, which is when electronically unstable atoms or molecules damage cells. The MU study yields […]
Posted in Chemicals, Disease/Health Effects, Paraquat, Parkinson's, Rotenone | No Comments »
20
Jun
(Beyond Pesticides, June 20, 2011) In a study published this week in the journal Pediatrics, researchers report findings that link mothers’ exposure to organochlorine pesticides during pregnancy with infants’ sizes at birth. The trend shows that the more mothers are exposed to the pesticides during pregnancy, the higher the chances are for reduced birth weight and length of their newborns. Comprising a total of 494 women and infants in Valencia, Spain from the years 2003-2006, the study evaluates umbilical cord blood for residues of four pesticides or pesticide degradates: DDT, DDE, hexachlorobenzene (HCB), and beta-hexachlorocyclohexane. The results show that a 10-fold increase in pesticide concentrations in the blood corresponds to a reduction in birth weight of 2-4 ounces. Additional results are correlated to specific pesticides. Higher concentrations of DDT results in a reduction in head circumference of 0.26cm, which the researchers call a “significant decrease.” Additionally, a decrease of 0.39cm in birth length is correlated with each 10-fold increase in concentration of HCB. The researchers note several concerns related to the findings, aside from the results themselves. Since people are exposed to a wide variety of chemicals in general throughout their everyday lives, higher pesticide exposure could betray higher exposure […]
Posted in Biomonitoring, Birth defects, DDT, Endocrine Disruption, hexachlorobenzene (HCB) | No Comments »