(Beyond Pesticides, September 29, 2023) In unsurprising news, the Environmental Protection Agency (EPA) has reversed itself and decided not to ban a dangerous pesticide: tetrachlorovenphos (TCVP) used in pet flea collars and other flea products. This is despite its own earlier decision to ban TCVP in pet collars and scathing criticism of its methods and conclusions by the courts. First registered in 1966, TCVP belongs to the notoriously toxic organophosphate chemical family and is classified by the World Health Organization as “possibly carcinogenic to humans.” It was originally registered to Shell Chemical, then to E.I. duPont de Nemours, then to Hartz Mountain Corporation and Fermenta Animal Health Company.  Early on, it was registered for use on food crops and livestock, but the crop uses were voluntarily de-registered in 1987. It is still widely used on pets and farm animals. In 1995, EPA issued the opinion that “all uses of tetrachlorvinphos, with the exception of oral feed-through larvicide treatment to livestock intended for food use, will not cause unreasonable risk to humans or the environment.” Since then, the agency has contorted itself repeatedly to allow TCVP to remain on the market. There is little research available on TCVP’s human health effects; the […]

(Beyond Pesticides, September 27, 2023) A study published in Pesticide Biochemistry and Physiology finds organophosphate (OP), organochlorine (OC), and pyrethroid (PYR) pesticides have links to insulin resistance (IR) associated with metabolic disorders like diabetes, obesity, chronic kidney disease (CKD), and hypertension. Metabolic disorders are among the leading causes of morbidity and mortality, with over 11 percent (>37 million) of individuals in the U.S. having diabetes, and cases are growing by millions annually. Additionally, there is a rise in metabolic disorders among young people. Studies even find low levels of pesticide exposure during pregnancy or childhood cause adverse health effects, including metabolic disorders tied to gut microbiome disruption (dysbiosis). With increasing rates of diabetes and obesity, the two most prominent metabolic diseases in the study, cases among the global population, studies like these highlight the importance of evaluating how chemical contaminants deregulate normal bodily function through metabolic changes.  To investigate the association between pesticide exposure and insulin-related metabolic disorders in humans, researchers searched the PubMed database for articles, performing a systematic review. The study notes, “IR is defined as a pathological state in which a higher-than-normal level of insulin is required to produce the optimal response in cells.” The search generated 4,051 articles related to the topic. However, after excluding duplicates and […]

(Beyond Pesticides, September 21, 2023) A literature review published in Ciência & Saúde Coletiva finds environmental exposure to all classes of pesticides (fungicides, herbicides, insecticides) has an association with childhood astrocytoma (brain/central nervous system [CNS] tumor). CNS tumors represent half of all malignant neoplasms (tumors) in children. Although medical advancements in disease survival are progressing, childhood cancer remains the leading cause of death from disease among children. Furthermore, childhood cancer survivors can suffer from chronic or long-term health complications that may be life-threatening. The etiology or cause of childhood cancer involves the interaction of multiple components that include environment, lifestyle and genetics. However, emerging evidence indicates that environmental contaminants like pesticides (e.g., occupational exposures, air pollution, pesticides, solvents, diet, etc.) affect disease etiology. Pesticide contamination is widespread in all ecosystems, and chemical compounds can accumulate in human tissues, resulting in chronic health effects. Children are particularly vulnerable to the impacts of pesticide exposure, as their developing bodies cannot adequately combat exposure effects. Moreover, several studies demonstrate an association between environmental or occupational pesticide exposure and the risk of childhood cancer. Considering that maternal pesticide exposure can have a stronger association with cancer among children than childhood exposure, and newborns can still encounter pesticides, it is […]

(Beyond Pesticides, September 20, 2023) Higher concentrations of a pyrethroid metabolite (3-PBA) in the body have an association with increased osteoarthritis (OA) risk among US adults, according to a study published in BMC Public Health. Regardless of analysis sensitivity and population subgroup (e.g., sex, socioeconomic status, etc.), the association between pyrethroid exposure and OA remains. Osteoarthritis is a degenerative joint disease resulting from the degradation (breakdown) of joint cartilage and underlying bone. This disease affects 1 in 7 U.S. adults and is the fourth leading cause of disability in the U.S. Unfortunately, OA is one of the most recently attributed pesticide-induced diseases associated with this dangerous class of chemical insecticides—harm to individual Americans that the U.S. Environmental Protection Agency (EPA) is not considering when it registers pesticides. To remedy the significant deficiencies in EPA’s reviews and protect residents from chronic disease, more and more communities are transitioning to safer, organic pest management practices that do not require pyrethroids and other toxic synthetic pesticides. Thus, this study and others like it highlight the need for increased monitorization of pyrethroid exposure among the general population. Using data from the 1999–2002 and 2007–2014 National Health and Nutrition Examination Survey (NHANES), this study explores the relationship between pyrethroid exposure and osteoarthritis. NHANES is […]

(Beyond Pesticides, August 31, 2023) A study published in Environmental Research finds glyphosate levels in the body adversely affect neurological health. Specifically, oral intake (e.g., eating contaminated foods), inhalation, and dermal exposure to glyphosate lowered cognitive function scores, heightened likelihood of severe depressive symptoms, and impaired auditory (hearing) function. Thus, this study provides some of the first evidence linking glyphosate exposure to specific neurological health outcomes among the general U.S. population, indicating the need for further studies on mechanisms driving neurotoxicity and the medical significance over time. Although this study is among the first to highlight specific neurological effects from glyphosate exposure among the general population, this study is not the first to identify potential neurotoxicity from glyphosate exposure. (Previous research cited below.) The ubiquity of glyphosate uses in agriculture—which leaves residues of the toxic chemical in food—and in public areas (e.g., parks, and walkways) may mean that exposures to it represent a significant risk factor for the disease. Glyphosate is already implicated or proven in developing numerous health anomalies, including cancer. The neurological system, including the brain, spinal cord, and a vast network of nerves and neurons, is responsible for many bodily functions—from sensation to movement. However, pesticides play various roles in […]

(Beyond Pesticides, August 23, 2023) Researchers are investigating a cutting-edge method to identify the impact of pesticides on reproductive health—shrinking the wait time from months to weeks. Scientists at the University of California, Davis, are developing a method for identifying harmful chemicals in pesticides with the help of glowing fish. This scientific breakthrough could revolutionize pesticide research and help prevent long-term health problems caused by exposure to these chemicals.  Pesticide exposure can cause acute and long-term health problems for the human endocrine system, the hormone system that regulates many biological processes from reproduction to blood sugar, growth, and more. Beyond Pesticides has written about the connections between EPA-registered pesticides and involuntary abortions, reproductive cancers, pregnancy loss, early-onset puberty, and more.   The American Academy of Pediatrics (AAP) has expressed concern over the limited or missing data regarding the health effects of pesticides and food additives on infants and children, who are more vulnerable to chemical exposures. AAP has identified several compounds as being of particular concern, including bisphenols, which are commonly used in the lining of metal cans; phthalates, which are used in adhesives and plasticizers; nonpersistent pesticides, which have been addressed in a previous AAP policy statement; perfluoroalkyl chemicals (PFCs), […]

A recently completed study (available in preprint before peer review) identifies the development of what the authors term Toxicant-Induced Loss of Tolerance (TILT), the constellation of symptoms associated with chemical exposures.

(Beyond Pesticides, August 16, 2023) A study published in Environmental Science and Pollution Research further supports the indication that exposure to organophosphate insecticides (OPs) increases the risk of asthma among the U.S. general population. According to the Asthma and Allergy Foundation of America, “The burden of asthma in the United States falls disproportionately on people with low-income, senior adults, and Black, Hispanic and American Indian/Alaska Native people,” making these groups more susceptible to developing this chronic lung disease upon OP exposure.   Organophosphorus pesticides have a wide range of biological uses—from insecticides to flame retardants—that make these chemicals ubiquitous, significantly contributing to ecosystem contamination. Furthermore, while organophosphates have less bioaccumulation potential, residues are consistently present in human and animal blood, urine, tissues, and milk. Although research demonstrates that OPs are highly toxic, there remains an inadequate understanding of how OP exposure impacts body systems like the repository system. The respiratory system is essential to human survival, regulating gas exchange (oxygen-carbon dioxide) in the body to balance acid and base tissue cells for normal function. However, damage to the respiratory system can cause several issues—from asthma and bronchitis to oxidative stress that triggers the development of extra-respiratory manifestations like rheumatoid arthritis and cardiovascular disease. Therefore, the rise in respiratory illnesses and organophosphate […]

(Beyond Pesticides, August 11, 2023) Reinforcing earlier findings, a systematic review published in Chemosphere finds the popular herbicide glyphosate and its formulations (glyphosate-based formulations-GBF) exhibit five out of the ten key characteristics (KC) of carcinogens (cancer-causing chemicals). Specifically, glyphosate exhibits strong evidence of genotoxicity, epigenetic alterations (heritable changes in gene expression), oxidative stress, chronic inflammation, endocrine disruption, and disturbs gut microbiota implicated in lymphomagenesis (growth and development of lymphoma). Although organizations like the International Agency for Research on Cancer (IARC) designate glyphosate as a probable human carcinogen, and scientific literature supports the findings on these adverse effects purported by glyphosate, the chemical remains on the U.S. market in various formulations. Glyphosate is the most commonly used active ingredient worldwide, appearing in many herbicide formulas, not just Bayer’s (formerly Monsanto) Roundup®. The use of this chemical has been increasing since the inception of crops genetically modified to tolerate glyphosate over two decades ago. The toxic herbicide readily contaminates the ecosystem with residues pervasive in food and water commodities. In addition to this study, literature proves time and time again that glyphosate has an association with cancer development, as well as human, biotic, and ecosystem harm. Therefore, advocates point to the need for national policies to reassess hazards associated with […]

(Beyond Pesticides, August 8, 2023) A study published in PLOS ONE finds a pointed, positive association between chronic kidney disease (CKD) of unknown origins (CKDu) and the use of indoor pesticides. Longer exposure times have an especially detrimental impact on kidney function, even among individuals without underlying diseases like diabetes mellitus and hypertension. The innovation of this study’s purpose highlights the lack of exposure-related studies on kidney health outcomes associated with indoor pesticide use. Although CKD risk increases with age and is associated with other health factors like smoking, heart disease, and diabetes, cases without clear causes are increasingly common, indicating that environmental factors are likely playing a role. Over six million people in the U.S. have kidney disease (i.e., nephritis [kidney inflammation], nephrotic syndrome [improper protein filtration], and nephrosis). Although many studies find an association between exposure to outdoor environmental contaminants like pesticides and CKD, the association between CKDu and indoor pesticides—whose uses are more commonly concentrated in homes— remains unclear. Therefore, studies like this highlight the need for comprehensive information regarding co-occurring exposure patterns and disease prevalence that can have global implications.  The study notes, “Previous research has highlighted the potential harm of pesticides on kidney function, particularly in outdoor uses. Our findings raise […]

(Beyond Pesticides, August 2, 2023) A study published in Pest Management Science finds resistance to insecticides like pyrethroids are challenging attempts to control the mosquito Aedes aegypti (Ae. aegypti), the primary transmitter (vector) of dengue fever. While this study takes place in Bangladesh, resistance to biocides—whether to antibiotics, antimicrobials, or pesticides—is growing globally. Prevention of disease outbreaks is threatened by reliance on chemical biocides to which pathogens and their vectors develop resistance. In fact, resistance is predicted by elementary population genetics, and the speed of its evolution is directly related to the toxicity—that is, the strength of selection pressure—and inversely related to the generation length of the organism. (See PAY articles here and here, a PBS article here.) Insecticide resistance has been an issue since the introduction of DDT (dichlorodiphenyltrichloroethane) in the 1940s. Although most countries currently ban DDT use, the compound is not the only chemical pesticide promoting pest resistance. Several current-use insecticides pose the same threat. Areawide, indiscriminate spraying of insecticides is causing resistance to develop among many pests. Mosquitoes have become increasingly resistant to synthetic pyrethroids, in addition to other classes of insecticides, such as carbamates and organophosphates. Thus, this study demonstrates the need for sustainable and practical strategies […]

(Beyond Pesticides, August 1, 2023) The U.S. Environmental Protection Agency has announced that it is publishing a decade’s worth of pesticide incident data in a searchable database that will be updated on a monthly basis. The Incident Data System (IDS), with poisoning reports generated mostly from chemical manufacturers, states, a national hotline, and poison control centers, offers information on reported pesticide exposures from accidental poisoning of pets, wildlife, and humans, to pesticide drift, noncompliance, and other pesticide incidents that may be associated with product uses in compliance with label instructions. Tracking this incident data is essential to understanding the risks and damages associated with pesticide use.   The bulk of the data on incidents is from consumer reports to chemical manufacturers. Chemical companies are required under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), Section 6(a)(2) to report incidents: “If at any time after the registration of a pesticide the registrant has additional factual information regarding unreasonable adverse effects on the environment of the pesticide, the registrant shall submit such information to the Administrator.” The determine of threshold number of incidents required to be reported as a pattern of “unreasonable adverse effects” is left to the manufacturers to determine. Through […]

(Beyond Pesticides, July 31, 2023) As the national debates on the rights of women to make health decisions about their bodies in the context of abortions, the scientific literature is increasingly documenting involuntary spontaneous abortions and other reproductive effects associated with pesticide exposure—raising critical questions about the ability to control one’s health. Last week, Beyond Pesticides reported on an exploratory study, published in Environment International, that adds to the many studies demonstrating residential prenatal pesticide exposure can result in adverse birth outcomes. Residential exposure to five active pesticide ingredients (Ais) fluroxypyr-meptyl, glufosinate-ammonium, linuron, vinclozolin, and picoxystrobin has adverse effects on gestational age (GA), birth weight (BW), mortality after birth, child’s sex, premature development, low birth weight (LBW), small for gestational age (SGA), and large for gestational age (LGA).  Despite the political furor surrounding medical abortions, the U.S. Environmental Protection Agency (EPA) continues to allow pesticides that cause involuntary spontaneous abortions (miscarriages) and other reproductive effects in exposed women. Tell EPA to ban pesticides that cause involuntary spontaneous abortions (miscarriages) and other reproductive effects. Tell Congress to ensure that EPA does not permit the use of pesticides affecting reproduction.  Most spontaneous abortions occur during the first trimester. The most common cause of miscarriage during the first […]

(Beyond Pesticides, July 26, 2023) An exploratory study published in Environment International adds to the many studies demonstrating residential prenatal pesticide exposure can result in adverse birth outcomes. Residential exposure to five active pesticide ingredients (Ais) fluroxypyr-meptyl, glufosinate-ammonium, linuron, vinclozolin, and picoxystrobin has adverse effects on gestational age (GA), birth weight (BW), mortality after birth, child’s sex, premature development, low birth weight (LBW), small for gestational age (SGA), and large for gestational age (LGA). Pesticides’ presence in the body has implications for human health, especially during vulnerable life stages like childhood, puberty, pregnancy, and old age. Pesticide exposure during pregnancy is of specific concern as health effects for all life stages can be long-lasting. Birth and reproductive complications are increasingly common among individuals exposed to environmental toxicants like pesticides. The Centers for Disease Control and Prevention (CDC) reports birth defects are the leading cause of infant mortality, with one in every 33 infants born with an abnormality that results in death. Therefore, studies like this can help government and health officials safeguard human health by assessing adverse effects following prevalent chemical exposure.  Using a Dutch birth registry from 2009 to 2013, the researchers selected pregnant mothers over 16 years who were living in non-urban areas (who […]

(Beyond Pesticides, July 19, 2023) A study in Environment International (August issue) by the United States Geological Survey (USGS) finds that almost half of U.S. tap water is contaminated with PFAS chemicals, with measured concentrations in both private wells and public water sources. Authors of the study “estimate that at least one PFAS could be detected in about 45% of U.S. drinking-water samples.” Although there are more than 12,000 different types of PFAS, only 32 are detectable by USGS lab tests, so 45% is likely a low estimate.  Per- and polyfluoroalkyl substances (PFAS) are a group of chemicals found in a variety of common household products such as nonstick pans and stain resistant carpeting, as well as pesticides and biosolids used as fertilizer. Long-chain PFAS, such as PFOA and PFOS, are more widely known because of their high toxicity and controversial use in the past. Today, long-chain PFAS are often replaced with short-chain PFAS, as the latter are not as bioaccumulative; however, short-chained PFAS also pose a significant threat because they remain highly persistent in the environment. Past Beyond Pesticides’ articles have described the prevalence of PFAS in products as well as their negative health consequences, including cancer, decreased fertility, […]

(Beyond Pesticides, July 13, 2023) A study published in Environmental Science and Pollution Research finds exposure to p-Dichlorobenzene (p-DCB), a chlorophenol compound with uses as an insecticide, disinfectant, repellent, fumigant, fungicide, and deodorizer, can increase the risk of common endocrine (hormone)-mediated reproductive cancers (i.e., breast, uterine, and ovarian) in women. P-DCB or paradichlorobenzene has carcinogenic (cancer-causing) properties and the chemical has been banned in the European Union (EU) since 2005 for air fresheners and 2008 for mothballs. Being a chlorinated aromatic hydrocarbon (with benzene) compound (chlorobenzene), in addition to its cancer-causing properties, p-DCB can cause acute illnesses like headaches, numbness, sleepiness, nausea and vomiting and chronic effects like nervous system disorders leading to depression, and impact on the brain, birth outcomes, reproductive system, liver, and kidneys. Pesticides have a long history associated with endocrine-disrupting properties that induce various molecular changes, prompting disease development. Adding to the science, a similar review published in Environmental Exposure, Biomonitoring, and Exposure Assessment highlights how specific estrogen-mimicking pesticides increase the risk of disease, particularly hormone-related cancers among women (e.g., breast, ovarian, and endometrial cancer) and men (i.e., testicular, prostate cancer).PDCB, also known as para-dichlorobenzene, contains the carcinogen benzene and is chlorine-based (a chlorinated aromatic hydrocarbon compound), which in December 2019 […]

(Beyond Pesticides, July 11, 2023) A study published in Parkinsonism & Related Disorders finds high exposure to household pesticides increases the risk of developing Parkinson’s disease (PD) two-fold. There is a multitude of epidemiologic research on Parkinson’s disease demonstrating several risk factors, including specific genetic mutations and external/environmental triggers (i.e., pesticide use, pollutant exposure, etc.). However, several studies find exposure to chemical toxicants, like pesticides, has neurotoxic effects or exacerbates preexisting chemical damage to the nervous system. Past studies suggest neurological damage from oxidative stress, cell dysfunction, and synapse impairment, among others, can increase the incidence of PD following pesticide exposure. Despite the widespread commercialized use of household pesticides among the general population, few epidemiologic studies examine the influence household pesticides have on the risk of PD, although many studies demonstrate the association between PD onset via occupational (work-related) pesticide exposure patterns. Parkinson’s disease is the second most common neurodegenerative disease, with at least one million Americans living with PD and about 50,000 new diagnoses annually. Alzheimer’s ranks first. The disease affects 50 percent more men than women, and individuals with PD have a variety of symptoms, including loss of muscle control and trembling, anxiety and depression, constipation and urinary difficulties, dementia, and […]

The introduction of the Agricultural Labeling Uniformity Act in the U.S. House of Representatives, expected to be a part of the Farm Bill negotiations, is raising the specter (yet again) of undermining local and state authority to protect the health of their residents from pesticides—effectively overturning decades of Supreme Court precedent.

(Beyond Pesticides, July 6, 2023) A study published in Environmental Health Perspectives finds concentrations of organophosphate (OP) metabolites in urine during the prenatal phase have links to adolescent/young adult externalizing (e.g., hyperactivity, aggression, attention problems) and internalizing (e.g., depression) behavior problems. Thus, prenatal exposure to OP pesticides can permanently affect behavioral health as children mature into adulthood. This study adds to the growing body of research reinforcing the adverse effects of organophosphate (OP) exposure on cognitive health and neurological development, especially for infants and children. Prenatal development is one of the most vulnerable periods of exposure, as the fetus is most susceptible to the harmful effects of chemical contaminants. Many studies indicate that prenatal and early-life exposure to environmental toxicants increases susceptibility to diseases, from learning and developmental disabilities to cancer. Given research links to pesticide exposure and neurological and cognitive development, studies like this can help government and health officials identify how pesticides’ impact on the brain elevates health concerns.  Researchers gathered two urine samples from mothers during pregnancy (at weeks 13 and 26) and five urine samples from offspring from the ages of six months to five years old to measure urinary dialkylphosphates (DAPs) (nonspecific OP metabolites). Subsequently, the study also assesses reports of […]

(Beyond Pesticides, June 30, 2023) Exposure to environmentally relevant concentrations of the herbicide glyphosate (GLY) has the potential to induce heart damage (cardiotoxicity) through the aging (senescence) of cells and a reduction of the number of rapidly increasing (proliferating) cells, according to a study published in Ecotoxicology and Environmental Safety. Specifically, glyphosate induces toxic effects on cardiomyocytes (cardiac muscles) responsible for contractions that pump the blood. Cardiovascular (heart) disease (CVD) is one of the leading causes of death in the U.S., with approximately 700,000 people dying annually of heart disease, equating to 25% of all U.S. deaths. Additionally, heart conditions are one leading cause of disability in the U.S. Research has shown that environmental pollutant exposure can increase the risk of developing cardiovascular disease, including stroke, heart attack, heart failure, atrial fibrillation, and cardiac arrest. Considering chemical exposure exacerbates adverse disease effects, reviews like these highlight the significance of evaluating synergism between diseases and toxic chemicals to safeguard human health. The study warns, “Our findings offer important information regarding the potential mechanisms of GLY cardiotoxicity toxicity. Notably, our study provides new insights into the relationship between GLY and senescence. Cardiac dysfunction of GLY to non-target organisms need to be noted in future study. Our study raises concerns about the […]

(Beyond Pesticides, June 29, 2023) In the first major settlement amid an influx of PFAS litigation, industrial chemical giants DuPont, Chemours, and Corteva will pay $1.185 billion dollars to cities and towns across the U.S. to cover the cost of PFAS remediation and monitoring in public drinking water systems. The significance of this nationwide class-action settlement cannot be overstated, as citizens have battled powerful chemical corporations for decades with limited success. Dangerous toxicants have been indiscriminately discharged into the environment by chemical companies since the mid-1900s, and the PFAS litigation is important in the company’s acceptance of responsibility for contamination. Of course, the damage to health and the environment is incalculable, given the pervasive environmental contamination and poisoning that it has caused, and additional lawsuits are pending, with more expected. Advocates maintain that this case exemplifies the inadequacies of regulatory controls that do a poor job of capturing the long-term effects of chemicals before being introduced into the market and a worse job of questioning the essentiality of toxic substances for which there are alternative practices and products. PFAS bring into sharp focus the legacy of chemical contamination and the impact on  future generations—a problem well-documented with pesticides like DDT […]

(Beyond Pesticides, June 28, 2023) An autopsy report from the Broward County Medical Examiner’s office in Florida found that acute exposure to the fumigant sulfuryl fluoride resulted in the death of two pest control workers from Pompano Beach. After the fumigation of a Pompano Beach warehouse in April, three workers fell ill, and two died after pesticide application. The highly toxic chemical can be used by the chemical pest control industry for killing termites, powder post beetles, old house borers, bedbugs, carpet beetles, moths, cockroaches, rats, and mice. In addition to being highly acutely toxic, sulfuryl fluoride, as a fluoride compound, can cause various chronic adverse health effects, including cancer, endocrine disruption, neurotoxicity (reduced IQ), and reproductive damage. This case represents the broader issue of how toxic chemical compounds can enter the body, causing physiological damage. In fact, just last March 2023, a case report article published in Frontier in Public Health confirms one of the first reported deaths from inhalation of the fumigant 1,3-dichloropropene (1,3-D or Telone) during work, resulting in acute renal (kidney) failure, hyperkalemia (high potassium levels in the blood), and brain edema (swelling). Considering over 300 environmental contaminants and their byproducts, including pesticides, are chemicals commonly present in human blood and urine samples, toxicity risk increases when entering the […]

(Beyond Pesticides, June 14, 2023) A study published in Scientific Reports finds a link between pesticide exposure and recurrent pregnancy loss (RPL) through oxidative stress and apoptosis (cell death) in the placenta. Recurrent pregnancy loss (RPL) is the loss of three or more successive pregnancies before 24 weeks of gestation (pregnancy) and signifies an underlying reproductive health issue. The study highlights that pesticides’ endocrine-disrupting (ED) properties can have varying adverse impacts on biological processes, including immunology, metabolism, and reproduction. Pregnant women experience frequent exposure to environmental pollutants that pose serious health risks to both mother and newborn. Many known pollutants (e.g., heavy metals, polychlorinated biphenyl, and pesticides) are chemicals with ED properties that can move from the mother to the developing fetus at higher exposure rates. Additionally, pregnant women are experiencing exposure to an increasing number of dangerous industrial chemicals. With a range of scientific data highlighting chemical exposures during pregnancy as a critical window of vulnerability, public awareness of these threats is growing. The study notes, “They are associated with an increasing placental OS [oxidative stress] and placental apoptosis. Specific measures should be taken to decrease maternal exposure to these pollutants’ sources, especially in underdeveloped and developing countries.” For RPL, the research investigated pesticide components in blood plasma, […]