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Daily News Blog

Archive for the 'RNAi' Category


20
Mar

“Biopesticides” Critiqued as Poorly Defined and Regulated, Challenging Safety Assumptions and Use

(Beyond Pesticides, March 20, 2026) Biopesticides represent a kind of Utopian destination in the landscape of agricultural sustainability. If only they could ensure planetary harmony. A review of botanical biopesticides in the March 11 issue of Toxics raises important questions that require scrutiny and review under the pesticide registration process and when used in organic systems under the Organic Foods Production Act. The term biopesticide can be misleading, and any replacements for synthetic pesticides cannot be taken only on faith. As Beyond Pesticides has noted previously, the U.S. Environmental Protection Agency’s (EPA) definition of biopesticides—“derived from such natural materials as animals, plants, bacteria, and certain minerals”—is broad, vague, and used differently by different interests. EPA regulates biopesticides under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) in three categories: Substances that interfere with mating, such as insect sex pheromones, as well as various scented plant extracts that attract insect pests to traps; Microbial pesticides consisting of a microorganism (e.g., a bacterium, fungus, virus, or protozoan) as the active ingredient; and Plant-Incorporated-Protectants (PIPs), pesticidal substances that plants are genetically engineered to produce. The review by Sandra Petrovic, PhD, and Andreja Leskovac, PhD, of the University of Belgrade, highlights the need not to […]

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11
Mar

Take Action: Call for Moratorium on the Release of RNAi Pesticides that Manipulate Genes

(Beyond Pesticides, March 11, 2019)  We must stop the expanded commercialization of genetically engineered pesticides. The failure of the U.S. Environmental Protection Agency (EPA) to fully evaluate environmental impacts of gene-manipulating pesticides raises serious concerns in light of the agency’s ongoing failure to predict ecological effects of pesticides, such as the dramatic decline of pollinators. With the release of a 2019 peer-reviewed scientific article, Environmental Fate of RNA Interference Pesticides: Adsorption and Degradation of Double-Stranded RNA Molecules in Agricultural Soils, on the potential impact on soil and non-target microorganisms in soil, the study’s co-author, Kimberly Parker, PhD, remarked, “The ecological risk assessment of these emerging pesticides necessitates an understanding of the fate of dsRNA [double stranded RNA] molecules in receiving environments, among which agricultural soils are most important.” This technology, given that it is systemic to the plant and leaves traces in the soil, can cause widespread indiscriminate poisoning—as has been seen with bees, butterflies, birds, and the larger catastrophic decline of insect populations. Tell your members of Congress that the ecological effects of RNAi gene-manipulating pesticides raise serious questions—they have not been fully studied by EPA and, until they are, the agency should issue a moratorium on their release. Previously, […]

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08
Mar

Study Raises Ecological Concerns about EPA-Approved RNAi Pesticides that Turn Off Genes

(Beyond Pesticides, March 8, 2019) Researchers from the U.S. and Switzerland have published their findings, a beginning assessment of how use of a new category of pesticides — dsRNA (double stranded RNA), which is less a traditional pesticide than a genetically based pesticide “technology” — might impact soils and non-target microorganisms in the soil. The co-authors (Kimberly M. Parker, PhD, et al.) note that, “The ecological risk assessment of these emerging pesticides necessitates an understanding of the fate of dsRNA molecules in receiving environments, among which agricultural soils are most important.” Their research appeared in late January 2019 in Environmental Science & Technology. Previously, technical hurdles in measuring dsRNA had stymied scientists’ ability to quantify the genetic material and its degradation products in soil, but these investigators were able to attach a radioactive atom to the molecule, “tagging” it so it could be followed through a series of simulated soil systems representative of those in the “real” world. Researchers were able to measure the presence of the material at concentrations as low as a few nanograms of dsRNA per gram of soil. The work of these researchers represents the beginning of understanding the ecological risks of these emerging dsRNA pesticides. They demonstrated […]

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