(Beyond Pesticides, May 14, 2009) President Barack Obama signed an executive order on Tuesday creating a Federal Leadership Committee for the Chesapeake Bay to be chaired by the U.S. Environmental Protection Agency. The executive order calls for EPA and six other federal agencies to coordinate and expand federal tools and resources to help speed cleanup of the nation’s largest estuary. At the meeting of the Chesapeake Bay Program Executive Council at Mount Vernon, Virginia, EPA Administrator Lisa P. Jackson presented the executive order, which creates the Federal Leadership Committee for the Chesapeake Bay. The Executive Council confirmed at a 2007 meeting that the Bay Program would not meet its commitment to clean up the Bay by 2010 as per the 2000 Chesapeake Bay Agreement. At that meeting, short-term two-year deadlines were set. However, since measures to improve the Bay’s heath have not been successful in the nine years since stakeholders were tasked with its clean-up, it is unclear how these milestones will be met by the two-year deadline in 2011. Chairman of the Chesapeake Executive Council, Virginia Governor Timothy Kaine, stated at the 2007 meeting that shorter term goals create the pressure to produce results. Many states are now tasked […]

(Beyond Pesticides, April 30, 2009) On April 20, the National Marine Fisheries Service (NMFS) released a Biological Opinion (BiOp) finding that three additional pesticides, carbaryl, carbofuran, and methomyl, harm salmon and steelhead protected under the Endangered Species Act (ESA). The BiOp prescribes measures necessary to keep these pesticides out of salmon waters in Washington, Oregon, California, and Idaho. It is the second such plan issued in the last six months under a court settlement with fishermen and conservationists, filed by the non-profit law firm Earthjustice. The previous BiOp identified three organophosphate insecticides: chlorpyrifos, diazinon, and malathion. “These pesticides are designed to kill insects on agricultural crops, but when they get into the water system, they also kill aquatic insects that salmon feed on.” said Angela Somma, who heads the NMFS endangered species division. Under the terms of settlement, the Environmental Protection Agency (EPA) must implement measures within a year-long timeframe to prevent further exposure of the pesticides to the water that cultivate these species. The measures recommended by NMFS include: a ban on application of the three pesticides in windy conditions and buffer zones near water resources and require that land applications must be at least 50-600 feet from the […]

(Beyond Pesticides, April 13, 2009) Rebuffing the Department of Agriculture, the Justice Department announced that it will not seek rehearing of a recent significant environmental decision that enables improved protection from pesticides under the Clean Water Act. In a letter dated March 6, 2009, Agriculture Secretary Vilsack had asked EPA Administrator Jackson to request reversal of the 6th Circuit’s decision (The National Cotton Council et al. v. EPA) in January that invalidated a Bush EPA rule exempting pesticide spraying around waterways from the Clean Water Act regulations. “This decision means that EPA recognizes its responsibility to move forward with implementing the Clean Water Act, instead of trying to circumvent this bedrock public protection statute as was attempted by the Bush EPA,” stated Charlie Tebbutt of the Western Environmental Law Center, who argued the case for the environmental plaintiffs. “We now look forward to working with EPA and the states to bring about meaningful changes in site specific uses of pesticides to protect our nation’s waters,” continued Mr. Tebbutt. In this same announcement, EPA stated that it will seek to continue the Bush rule for two years, despite the court ruling it illegal. “This part of the EPA’s decision is troubling,” […]

(Beyond Pesticides, April 1, 2009) A study published in the April 2009 issue of the medical journal Acta Paediatrica reports that the highest rates of birth defects for U.S. babies arise when conception occurs during the spring and summer months, when pesticide use increases and high concentrations of pesticides are found in surface waters. The study entitled, “Agrichemicals in surface water and birth defects in the United States” is the first study to link increased seasonal concentration of pesticides in surface water with the peak in birth defects in infants conceived in the same months. Researchers analyzed all 30.1 million births in the U.S. between 1996 and 2002. A strong association between higher rates of birth defects among women whose last menstrual period was in April, May, June or July and elevated levels of nitrates, atrazine and other pesticides in surface water during those same months was found. The correlation between the month of last menstrual period and higher rates of birth defects is statistically significant for half of the 22 categories of birth defects reported in the Centers for Disease Control database from 1996 to 2002, including spina bifida, cleft lip, clubfoot and Down’s syndrome. “Elevated concentrations of pesticides […]

(Beyond Pesticides, March 31, 2009) More than 20 percent of private domestic wells sampled nationwide contain at least one contaminant at levels of potential health concern, according to a study by the U.S. Geological Survey (USGS). About 43 million people – or 15 percent of the Nation’s population – use drinking water from private wells, which are not regulated by the federal Safe Drinking Water Act. USGS scientists sampled about 2,100 private wells in 48 states and found that the contaminants most frequently measured at concentrations of potential health concern were inorganic contaminants, including radon and arsenic. These contaminants are mostly derived from the natural geologic materials that make up the aquifers from which well water is drawn. Nitrate was the most common inorganic contaminant derived from man-made sources””such as from fertilizer applications and septic-tanks””that was found at concentrations greater than the federal drinking-water standard for public-water supplies (10 parts per million). Nitrate was greater than the standard in about four percent of sampled wells. Other contaminants found in the private wells were man-made organics, including herbicides, insecticides, solvents, disinfection by-products, and gasoline chemicals. The study shows that the occurrence of selected contaminants varies across the country, often following distinct […]

(Beyond Pesticides, March 11, 2009) The new administrator of the U.S. Environmental Protection Agency (EPA), Lisa Jackson, has put discussions with Dow Chemical Co. concerning dioxin contamination on hold, citing a need to have the process open and transparent. Negotiations with the industry giant began in the mid-1990s over how to clean-up dioxin contamination along 50 miles of rivers and floodplains of Lake Huron’s Saginaw Bay watershed in Michigan. Dow has long been accused of moving too slowly to restore the polluted watershed. Ms. Jackson announced her decision last week in a letter to environmental activists involved with the issue. She also stated that a team of high-ranking officials from her office would meet shortly with activist groups, as well as representatives of Dow and the Michigan Department of Environmental Quality (DEQ). The letter states that the EPA’s regional office in Chicago would not participate in further negotiations until her team has reported back after its meetings in Michigan. The meetings are expected to take place next week. “My goal is to ensure an expeditious and robust cleanup, and I will take steps to ensure that the dioxin contamination is addressed in a manner that is protective of human health […]

(Beyond Pesticides, March 5, 2009) A new study published in the March 2009 issue of Environmental Health Perspectives finds that pesticide combinations cause more harm to endangered salmon than ndividual pesticide exposure. This means that single-pesticide risk assessments required by the Environmental Protection Agency (EPA) inadequately assess hazards. Mixtures of organophosphate and carbamate pesticides are commonly detected in freshwater habitats that support threatened and endangered species of Pacific salmon. According to the researchers from the National Oceanic and Atmospheric Administration (NOAA) Fisheries and Washington State University, these pesticides inhibit the activity of acetylcholinesterase (AChE) and thus have potential to interfere with behaviors that may be essential for salmon survival. The researchers measured brain AChE inhibition in juvenile coho salmon exposed to sublethal concentrations of the organophosphates diazinon, malathion, and chlorpyrifos, as well as the carbamates carbaryl and carbofuran. The pesticides were tested individually and in combination. They plotted AChE levels on a curve to determine whether the toxicologic responses to binary mixtures were additive, antagonistic (lesser than additive) effect, or synergistic (greater than additive). The authors observed addition and synergism, with a greater degree of synergism at higher exposure concentrations. Several combinations of organophosphates were lethal at concentrations that were […]

(Beyond Pesticides, February 11, 2009) Connecticut lawmakers are taking an interest in the much debated cause of a massive die-off of lobsters that has all but wiped out the state’s 40 million dollar industry, according to the Easton Courier. Fishermen and environmentalists blame the use of the insecticide malathion, a hazardous organophosphate, currently used in community mosquito eradication programs, however the state Department of Environmental Protection (DEP) argues that there is not enough scientific data to lead to the banning of the chemical. The huge die-off of lobsters began in 1999, days after towns in Fairfield County, Westchester County and Long Island, as well as New York City, sprayed malathion to kill mosquitoes carrying the West Nile virus. Also at that time, remnants of hurricane Floyd drenched the state and washed the pesticide into Long Island Sound. The DEP, however, says the storm caused many other factors that led to the mass die-off. However, the lobster population has yet to recover. State lawmakers find DEP’s position on malathion puzzling. Rep. Richard Roy (D-Milford), chair of the House Environment Committee, and Senate Assistant Majority Leader Bob Duff (D-Norwal) are questioning DEP about its efforts to restore the state’s lobster industry while […]

(Beyond Pesticides, February 4, 2009) A new test for triclosan, developed by researchers at the U.S. Department of Agriculture’s Agricultural Research Service (ARS), could help to expedite environmental monitoring of this widely used antibacterial chemical which has been found at high concentrations in rivers and other water resources. Triclosan is linked to a range of health and environmental effects, from skin irritation, bacterial resistance and endocrine disruption, to dioxin contamination and adverse impacts on fragile aquatic ecosystems. The new test called “magnetic particle enzyme immunoassay,” can detect triclosan at a concentration of 20 parts per trillion (ppt)-the equivalent of 1 ounce in 31 million tons. The research team at ARS evaluated the test by using it to detect triclosan and its derivative, methyl-triclosan, in river water, tap water and sewage samples from three municipal plants. They were able to detect triclosan below 20 ppt (the detection limit), indicating very low levels of triclosan in the collected samples. ARS chemist, Weilin L. Shelver, at the ARS Animal Metabolism-Agricultural Chemicals Research Unit in Fargo, N.D., developed the new triclosan test in collaboration with Jennifer Church, Lisa Kamp and Fernando Rubio, a research team at Abraxis, Inc., of Warminster, Pa. Ms. Shelver says […]

Beyond Pesticides will hold its 27th National Pesticide Forum, Bridge to an Organic Future: Opportunities for health and the environment, April 3-4, 2009 in Carrboro, NC (next to Chapel Hill and the University of North Carolina). This national environmental conference will include sessions on Pesticides and public health; Organic agriculture; Domestic fair trade; Organic lawns and landscapes; Healthy schools and daycare; Water contamination; and much more. Register online or call 202-543-5450 to register by phone. This national environmental conference, co-convened by Toxic Free North Carolina, is an important opportunity for community people nationwide to get together, share the latest information, meet with scientists and policy makers, and discuss local, statewide and national strategies on pest issues, pesticides, public health and the environment. As the home of the National Institute of Environmental Health Sciences (NIEHS) and recently named “America’s Foodiest Small Town,” the location is just the right place for participants to discuss fair, organic food and the impact of pesticides on public health. Keynote speakers for the conference include: Just added! Baldemar Velásquez, president of the Farm Labor Organizing Committee (FLOC), was raised as a migrant farmworker. Since his childhood, he has worked in the fields and orchards of many […]

(Beyond Pesticides, January 28, 2009) The U.S. Environmental Protection Agency’s (EPA) national sewage sludge survey identifies high concentrations of toxic contaminants with heavy metals, steroids and pharmaceuticals, including the antibacterials, triclocarban and triclosan. Despite the prevalence of these toxic chemicals in the environment and their potential adverse impacts to human health and the environment, EPA maintains that it is not appropriate to speculate on the significance of the results at this time. Under the Clean Water Act (CWA), Section 405(d) stipulates that EPA must identify and regulate toxic pollutants that may be present in biosolids (sewage sludge) at levels of concern for public health and the environment. The survey, “Targeted National Sewage Sludge Survey” (TNSSS), sampled 74 selected waste water treatment plants in 35 states during 2006 to 2007. The survey, like its three predecessors, is conducted to determine which chemicals are present in sewage sludge and develop national estimates of their concentrations in order to assess whether exposures may be occurring and whether concentrations found may be of concern. The agency conducted analysis of sewage sludge samples for 145 compounds, including four anions (nitrite/nitrate, fluoride, water-extractable phosphorus), 28 metals, four polycyclic aromatic hydrocarbons, two semi-volatiles, 11 flame retardants, 72 […]

(Beyond Pesticides, January 22, 2009) A new English study has found that chemicals found in rivers and waste waters could be linked to male infertility. These chemicals, known as anti-androgens, block the action of the male sex-hormone testosterone and could impact the development of male reproductive organs in humans. The study entitled, “Statistical Modeling Suggests That Anti-Androgens in Wastewater Treatment Works Effluents Are Contributing Causes of Widespread Sexual Disruption in Fish Living in English Rivers,” and published in the journal Environmental Health and Perspectives identifies a group of river pollutants that cause testosterone to stop working. These chemicals, released from wastewater treatment operations into rivers and other surface waters are responsible for the feminization of male fish and abnormalities in male reproductive organs. Previous studies have attributed these problems in male fish to estrogenic compounds also found in surface waters. However, this study is the first to identify anti-androgens with the feminization of male fish. It also indicates that male feminization may be the result of a rather more complicated interaction taking place between different classes of pollutants, resulting in an endocrine disrupting chemical cocktail. “We have identified a new group of chemicals in our study on fish, but we […]

(Beyond Pesticides, January 16, 2009) The first comprehensive look at toxic contamination throughout the Columbia River Basin has been released by the U.S. Environmental Protection Agency. Issued today, the Columbia River Basin State of the River Report for Toxics compiles currently available data about four widespread contaminants in the Basin and identifies the risks they pose to people, fish, and wildlife. The four contaminants are: * Mercury * Dichlorodiphenyltrichloroethane (DDT) and its breakdown products * Polychlorinated biphenyls (PCBs) * Polybrominated diphenyl ether (PBDE) flame retardants. According to Elin Miller, EPA Regional Administrator in Seattle, a team of more than 20 federal and state agencies, Tribes, local governments and organizations teamed-up to draw this latest portrait of the toxic threats faced by the Columbia River Basin, which drains nearly 260,000 square miles across seven U.S. states and a Canadian province. “This is troubling news,” said EPA’s Miller. “Today’s Report shows that toxics are found throughout the Basin at levels that could harm people, fish, and wildlife. Federal, tribal, state, and local efforts have reduced levels of some toxics such as PCBs and DDTs, but in many areas, they continue to pose an unacceptable risk. Tackling this problem will require a coordinated […]

(Beyond Pesticides, January 14, 2009) Two-headed bass found in the Noosa River are at the center of a controversy surrounding pesticide drift from neighboring farms in Queensland, Australia. The pesticides, endosulfan and carbendazim, have been implicated in the contamination of the river, which has yielded thousands of chronically deformed fish. Experts believe that the mutated fish, which survive only 48 hours after hatching, are the victims of pesticide drift from neighboring macadamia nut farms that routinely use endosulfan and the fungicide, carbendazim. Aquatic health expert and vice-president of the Australian College of Veterinarian Scientists’ Aquatic Animal Health Chapter, Matt Landos, PhD, has been investigating the phenomenon and concludes that there were no other probable causes to explain the fish and larval mortality. Dr. Landos documented evidence and completed a report which was sent to the state’s Department of Primary Industries and Fisheries last year. “The timing between the mist spraying and the affected larvae fits hand in glove,” Dr. Landos said. His report also found that chickens, sheep and horses raised at nearby fish hatcheries are also recording abnormally high levels of fetal deaths and birth defects. Gwen Gilson, who runs a Boreen Point fish hatchery, says she has observed […]

(Beyond Pesticides, January 13, 2009) In another stinging defeat for the Bush Environmental Protection Agency (EPA), on January 7, 2009, the 6th Circuit Court of Appeals issued a clear rebuke of the administration’s 2006 rule which exempted certain commercial pesticide applications from the oversight provided by Congress under the Clean Water Act. [The National Cotton Council et al. v. EPA (Nos. 06-4630; 07-3180/3181/3182/3183/3184/3185/3186/3187/3191/3236). See also Headwaters, Inc. v. Talent Irrigation Dist., 243 F.3d 526, 532-33 (9th Cir. 2001).] The Court held that pesticide residuals and biological pesticides constitute pollutants under federal law and therefore must be regulated under the Clean Water Act (CWA) in order to minimize the impact to human health and the environment. According to Beyond Pesticides, the EPA rule had allowed the weaker and more generalized standards under the Federal Insecticide, Fungicide and Rodenticide Act (FIFRA) to trump the more stringent CWA standards. CWA uses a kind of health-based standard known as maximum contamination levels to protect waterways and requires permits when chemicals are directly deposited into rivers, lakes and streams, while FIFRA uses a highly subjective risk assessment with no attention to the safest alternative. Read Beyond Pesticides’ press release on EPA’s 2006 decision. Several manufacturers […]

(Beyond Pesticides, January 9, 2009) Environmental Toxicology and Chemistry has published a study (Vol. 27(12):2496—2500) entitled “Effects of Malathion on Embryonic Development and Latent Susceptibility to Trematode Parasites in Ranid Tadpoles.” It shows that malathion used as an agricultural insecticide is responsible for interfering with the normal development of pickerel frog embryos, thus leaving them more susceptible to parasite invasion. Malathion is present in natural water sources that have been exposed to urban and agricultural runoff. This organophosphate pesticide can be applied by planes in mosquito control program, and as esult enters water from the air. Although direct lethal and sublethal effects of chemical contaminants have been documented, latent and long-term effects have been less well documented. Therefore, researchers sought to fill this knowledge gap and found, as suspected, that tadpole survival rates decreased and malformations and susceptibility to parasite encystment rates increased as a result of exposure to malathion concentrations mimicking those found in actual water sources. Tadpoles are being exposed to increasing numbers of parasites in waters that are warming as a result of global climate change, and the researchers who performed this study speculate that, as a consequence, those exposed to malathion will have weakened immune systems […]

(Beyond Pesticides, December 15, 2008) Striped bass in the San Francisco Estuary are contaminated before birth with a toxic mix of pesticides, industrial chemicals and flame retardants that their mothers acquire from estuary waters and food sources and pass on to their eggs, according to a new study by University of California Davis researchers. Using new analytical techniques, the study, “Maternal Transfer of Xenobiotics and Effects on Larval Striped Bass in the San Francisco Estuary” finds offspring of estuary fish have underdeveloped brains, inadequate energy supplies and dysfunctional livers. They grow slower and are smaller than offspring of hatchery fish raised in clean water. The findings have implications far beyond fish, because the estuary is the water source for two-thirds of the people and most of the farms in California. “This is one of the first studies examining the effects of real-world contaminant mixtures on growth and development in wildlife,” said study lead author David Ostrach, a research scientist at the UC Davis Center for Watershed Sciences. “If the fish living in this water are not healthy and are passing on contaminants to their young, what is happening to the people who use the water, are exposed to the same […]

(Beyond Pesticides, December 12, 2008) A new study has found pesticides in surface waters around the United States. The U.S. Geological Survey (USGS) analyzed water from nine selected rivers, which are used as a source for public water systems and found that low levels of certain xynthetic chemicals remain in public water supplies after being treated in selected community water facilities. “Most of the man-made chemicals assessed in the USGS study are unregulated in drinking water and not required to be monitored or removed,” says Tom Jacobus, General Manager of the Washington Aqueduct. “These findings are not surprising and they will be important in helping regulators and assisting water utility managers arrive at decisions about future water treatment processes.” Scientists tested water samples for about 260 commonly used chemicals, including pesticides, solvents, gasoline hydrocarbons, personal care and household-use products, disinfection by-products, and manufacturing additives. This study did not look at pharmaceuticals or hormones. Low levels of about 130 of the synthetic chemicals are detected in streams and rivers before treatment at the public water facilities (source water). Nearly two-thirds of these chemicals are also detected after treatment. Most of the chemicals found are at levels equivalent to one thimble of […]

(Beyond Pesticides, November 26, 2008) On November 10, two Alaskan environmental groups sued the United States Fish and Wildlife Service (FWS) for failing to conduct a proper assessment of the environmental consequences of using herbicides to kill non-native species in Kodiak National Wildlife Refuge and the Alaska Maritime National Wildlife Refuge. The groups, Alaska Survival and Alaska Community Action on Toxics, allege that FWS sprayed hundreds of gallons of herbicide in the Kodiak National Wildlife Refuge and the Alaska Maritime National Wildlife Refuge over the past several years. In the complaint to the U.S. District Court of Alaska, the groups say FWS violated the National Environmental Policy Act (NEPA) by failing to conduct adequate investigations on the environmental impacts of pesticide use and by failing to inform the public of the practice. The lawsuit states, “(Fish and Wildlife) failed to consider the potential harm to aquatic organisms, fish, birds, insects and other non-target species, as well as the potential for adverse effects to humans visiting the area,” and that the “defendants failed to consider the effect of herbicide use on the commercial salmon fishing industry and on subsistence users.” Under NEPA, all federal agencies are required to conduct an Environmental […]

(Beyond Pesticides, November 21, 2008) On November 18, the National Marine Fisheries Service (NMFS) released a biological opinion that sets forth a plan for protecting Pacific salmon and steelhead from three toxic organophosphate pesticides. The decision comes after almost a decade of legal wrangling between salmon advocates and the federal government. In the biological opinion, federal wildlife scientists comprehensively reviewed the science regarding the impacts of pesticides on salmon and ultimately concluded that current uses of the insecticides chlorpyrifos, diazinon, and malathion jeopardize the existence of these imperiled fish. The biological opinion prescribes measures necessary to keep these pesticides out of water and to protect salmon populations in Washington, Oregon, California, and Idaho. The new mitigation measures must be implemented within one year. They include: * Prohibiting aerial applications of the three pesticides within 1,000 feet of salmon waters * Prohibiting ground applications of the three pesticides within 500 feet of salmon waters * Requiring a 20 foot non-crop vegetative buffer around salmon waters and ditches that drain into salmon habitat * Prohibiting applications of the three pesticides when wind speeds are greater than or equal to 10 mph “Keeping these pesticides out of the water is a major step […]

(Beyond Pesticides, November 17, 2008) A toxic soup of the most commonly used pesticides frequently detected in nature can adversely affect the environment and decimate amphibian populations even if the concentration of the individual chemicals are within limits considered safe, according to University of Pittsburgh research published in the online edition of Oecologia. The results of this study build on a nine-year effort to understand potential links between the global decline in amphibians, routine pesticide use, and the possible threat to humans in the future. Amphibians are considered an environmental indicator species because of their unique sensitivity to pollutants. Their demise from pesticide exposure could foreshadow the fate of less sensitive animals, according to study author Dr. Rick Relyea, Ph.D., an associate professor of biological sciences in the University of Pittsburgh’s School of Arts and Sciences. Leopard frogs, in particular, are vulnerable to contamination; once plentiful across North America, their population has declined in recent years as pollution and deforestation has increased. Dr. Relyea exposed gray tree frog and leopard frog tadpoles to small amounts of the ten pesticides that are widely used throughout the world. Dr. Relyea selected five insecticides: carbaryl, chlorpyrifos, diazinon, endosulfan, and malathion; and five herbicides: […]

(Beyond Pesticides, November 5, 2008) The Environmental Protection Agency (EPA) acknowledged in a recent Federal Register Notice that antimicrobial pesticides in wide use are not adequately tested for their impacts on human health and the environment. Controversy surrounding the impacts of many antimicrobials in the environment has arisen in recent times to due to the prevalence of these chemicals in surface and drinking waters. Antimicrobials are defined by the EPA as “pesticides that are intended to (1) disinfect, sanitize, reduce, or mitigate growth or development of microbiological organisms, or (2) protect inanimate objects from contamination, fouling, or deterioration caused by bacteria, viruses, fungi, protozoa, algae, or slime.” For this proposal, the EPA is using the term antimicrobials to collectively refer to antimicrobial pesticides, antifoulant coatings and paints, and wood preservatives. The use of the controversial antimicrobial, triclosan, in inanimate objects, such as plastic and textiles, would be covered by these regulations, while those personal care products with the very same ingredient would not, since they fall under Food and Drug Administration authority. In the Federal Register last month, EPA, trying to play catch-up with the science while products continue in larger and larger numbers to incorporate the controversial antimicrobials, issues […]

(Beyond Pesticides, October 27, 2008) Six pesticides that threaten water quality and public health continue to be detected in groundwater samples, according to a new U.S. Geological Survey (USGS) study. Published in the Journal of Environmental Quality, the study evaluates groundwater contaminants from samples taken from over 300 wells across the U.S. Over the years, frequent research has detected pesticides in ground water around the country, including in aquifers used for drinking-water supply. Over the past few decades, the use of some pesticides has been restricted or banned, while new pesticides have been introduced. One goal of the study was to track the retention of various types of contaminants that would be found in the different pesticides used over the years. Original samples were taken from the wells from 1993-1995, and compared with samples taken from 2001-2003. Laboratory analysis was performed using methods that allowed detection of pesticide compounds at concentrations as small as 1,000 times below U.S. EPA drinking-water standards. Of the 80 compounds studied, six were detected in ground water from at least 10 wells during both of those sample periods. The six pesticide compounds detected are the triazine herbicides atrazine, simazine, and prometon; the acetanilide herbicide metolachlor; […]