(Beyond Pesticides, May 9, 2025) Research in Advances in Modern Agriculture showcases how pesticide residues can threaten the health of soil nematodes and cause phytotoxic effects in cucumber plants. In assessing both the sprayed vegetables and the organisms within the soil, the authors find a negative correlation between pesticide exposure and soil nematode populations that is proportional to the application rates of the chemicals, as well as alterations in plant development. These impacts highlight potential wider effects on crop productivity, biodiversity, and human health. “Nematodes, which are microscopic worms inhabiting the soil, are vital contributors to soil vitality and the cycling of nutrients,” the authors share. “Nonetheless, the non-selective and widespread application of pesticides can negatively impact these organisms, leading to potential detriments in soil quality and plant vitality.” “Pesticide residues have the propensity to be absorbed and progressively accumulate as they traverse from soil to plants and subsequently to humans,” the researchers state. They continue, “The specific characteristics of the pesticide and its interactions with the body across different levels dictate whether it will be excreted without causing significant harm or if it will accumulate, potentially leading to enduring subclinical and clinical ramifications.” The impacts vary widely between organisms […]

(Beyond Pesticides, April 25, 2025) A novel study in Chemosphere finds impacts on male fertility in a bee species (Osmia bicornis) with exposure to sulfoxaflor, a systemic sulfoximine insecticide with similar mechanisms to neonicotinoids. “For the first time, we demonstrate that short-term chronic, field-realistic exposure to a common pesticide reduced pre-copulatory display (36%) and sounds (27%) [courtship behaviors], increased the number of copulations (+110%) and the mating duration (+166%), while finally reducing sperm quantity (25%) and mating success (43%),” the researchers report. They continue, “Our research raises considerable concern on the impact of field-realistic, low sublethal pesticide levels on the fertility and reproductive success of pollinators.” Mating behaviors and the ability to successfully reproduce determines the survival of species. As the authors state: “Mating disorders may therefore contribute to the recent decline in insect and pollinators’ health worldwide. While the impact of pesticides on pollinators is widely considered as a driving factor for reducing pollinators’ health, their effect on mating behaviour and male fertility remains widely overlooked.” The red mason bee (O. bicornis) can “provide essential pollination service for both crops and wild plants sustaining food production and biodiversity while serving as a bioindicator of environmental health.” The abundance and […]

(Beyond Pesticides, April 23, 2025) Recent reviews of scientific literature, in both Chemosphere and Reports in Public Health, associate Parkinson’s disease (PD), the second most prevalent neurodegenerative disease globally, with pesticide exposure. “Given the pervasive nature of pesticide residues in everyday food consumption and inadequate monitoring of their long-term toxicological impacts, the role of pesticide exposure as a modifiable risk factor for neurological disorders, including PD, warrants urgent attention,” the researchers state in the article in Chemosphere. In describing the history of Parkinson’s and previous research, the authors in Reports in Public Health note that while PD etiology is not fully understood, it is a multifactorial disease. “Hereditary factors are present in approximately 10% of diagnosed cases of Parkinson’s disease, presenting early onset; while the other 90% of cases are categorized as idiopathic or sporadic Parkinson’s disease, occurring in older individuals and may be associated with exposure to environmental agents,” the researchers say. This disease, first described by English physician James Parkinson, M.D. in 1817, involves neurochemical changes that present as “the appearance of cardinal motor symptoms, such as bradykinesia, rigidity, postural instability, and rest tremor, which are essential for the clinical diagnosis of the disease,” the researchers note. The […]

(Beyond Pesticides, April 16, 2025) Documented for the first time, 15 currently used pesticides (CUPs) and four metabolites (breakdown or transformation products—TP) were found in the marine atmosphere over the Atlantic Ocean. Three legacy (banned) pesticides were also discovered. According to a recent study published in Environmental Pollution, researchers found empirical evidence for pesticide drift over remarkably long distances to remote environments. The findings of this study build on existing research that pollution knows no borders or boundaries, emphasizing Beyond Pesticides’ mission to advocate for the value of the precautionary principle through the elimination of synthetic chemicals and replacement with organic systems that address the root causes of pest pressures–including systemic failure to feed soil microbial life.   Background and Methodology “In this study, 329 pesticides, including 282 CUPs and 36 transformation products, were [sampled for] in the atmosphere across a south-north transect on the Atlantic Ocean,” said the authors. They unpack the three main objectives to address the focus and major objectives of their research: “[T]he determination of pesticide concentrations in the atmosphere of the Atlantic Ocean, The investigation of the spatial distribution of pesticides across the Atlantic Ocean, and The elucidation of potential sources and factors influencing pesticide transport […]

(Beyond Pesticides, April 15, 2025) A study in Communications Earth & Environment, through field, greenhouse, and laboratory experiments involving three plant bug species, finds both species-specific and sex-specific sensitivity responses to neonicotinoid insecticide exposure—highlighting the threats to grassland insect communities that are disregarded in risk assessments. By assessing the effects of Mospilan®SG, with the active ingredient acetamiprid, the researchers determine that nontarget plant bug species are highly sensitive to neonicotinoids and face community-level harm with exposure. As systemic insecticides, neonicotinoids move through the vascular system of plants, expressing the poison through pollen, nectar, and guttation droplets. As persistent pesticides, these chemicals indiscriminately poison insects and organisms in the soil. “Although pesticides have been proposed as one of the main causes of insect decline, there are still few studies assessing their effects on non-target species under field conditions,” the authors state. They continue: “In this study, we address the existing research gap on insecticide exposure of non-target herbivorous insects, focusing on two main aspects: (1) realistic exposure scenarios, (2) community-level effects, i.e., differential sensitivity between closely related species and between sexes of the same species. We chose plant bugs (Heteroptera: Miridae) as a model group because they are one of the […]

(Beyond Pesticides, April 4, 2025) In March, the California Department of Pesticide Regulation (DPR) announced the launch of SprayDays California, “a first-of-its-kind statewide system designed to provide transparent, accessible and timely notifications and information about the use of specific pesticides[,]“ according to the agency’s press release. The state says that notification will occur in “advance of the scheduled use of California restricted material pesticides in production agriculture.” Growing out of the passage of AB 617 Community Emissions Reduction Act in California, passed in 2017, farmworker safety advocates have long been urging an implementation strategy that provides notification of pesticide spraying. In late 2017, the California Air Resources Board (CARB) began implementation of AB 617, a bill enacted with the stated intent of addressing the air quality crisis in many communities of predominantly people of color who are disproportionately harmed by toxic chemicals. While the overall goal of the law is to reduce air pollution in these communities, farmworker advocates have sought to operationalize a pesticide spraying notification system to warn communities when nearby spraying is scheduled to take place. The idea behind notification programs and transparency in government is that it enables those potentially exposed to take precautionary measures to […]

(Beyond Pesticides, April 3, 2025) As highlighted by Beyond Pesticides in recent comments to the U.S. Environmental Protection Agency (EPA), chlorpyrifos (CPF) has been under scrutiny for decades due to associated adverse health effects, noted particularly in the extensive and consistent scientific evidence of neurotoxic dangers to children’s health. The latest research on CPF, published in Environmental Toxicology and Genes & Diseases, reveals additional threats to the immune system and male reproduction that are not captured in current EPA risk assessments of chlorpyrifos and raises serious health questions, given that residues are found throughout the food supply. CPF, a widely used organophosphate insecticide in agriculture, is a cholinesterase inhibitor that binds irreversibly to the active site of an essential enzyme for normal nerve impulse transmission, acetylcholine esterase (AChE), inactivating the enzyme. Many insecticides, including organophosphates and carbamates, target AChE, causing them to be highly toxic to both insects and mammals that have this enzyme as a crucial part of their nervous systems. The history of chlorpyrifos exemplifies the failure of pesticide law and policy, as this chemical, among many others, not only has direct adverse health effects but is contributing to the climate crisis, biodiversity collapse, and disproportionate levels of […]

(Beyond Pesticides, March 27, 2025) In Ecotoxicology, results of a study on Nile tilapia (Oreochromis niloticus) exposed to florpyrauxifen-benzyl (FPX) suggest the new herbicide causes oxidative stress (imbalances affecting the body’s detoxification abilities that lead to cell and tissue damage), with specific genotoxic (damage to genetic material) and hepatotoxic (damage to the liver) effects on nontarget species. The authors state: “According to the available literature, no data exist on the toxicity of FPX in fish. Therefore, this study aims to investigate, for the first time, the potential toxicity and associated mechanistic effects of the pyridine-carboxylic acid herbicide (FPX) on the non-target species, Nile tilapia.” According to the Wisconsin Department of Natural Resources, “Florpyrauxifen-benzyl is a systemic herbicide (i.e., it moves throughout the plant tissue). It is a WSSA Group 4 herbicide, meaning that the mechanism of action is by mimicking the plant growth hormone auxin and causing excessive elongation of plant cells, ultimately killing the plant.” The researchers, from Menoufia University, the Agricultural Research Center, and Cairo University in Egypt, focus on FPX as it is the active ingredient in Divixton 2.5% EC, a newly released herbicide used in rice fields and applied directly to freshwater aquatic bodies for emergent […]

(Beyond Pesticides, March 25, 2025) An editorial in Expert Review of Cardiovascular Therapy finds that triazole fungicides pose a significant risk of cardiotoxicity with “growing concerns regarding their safety for human health, especially in long-term exposure,” the authors share. After analyzing the known mechanisms of cardiotoxicity of triazole pesticides in mammals, they conclude that “the most effective approach to mitigating triazole-induced cardiotoxicity lies in prevention.”  Triazoles, a class of fungicides, target fungi by inhibiting the biosynthesis of ergosterol, an essential component of their cell membranes. As the researchers share, “Compounds such as tebuconazole, propiconazole, and difenoconazole are among the most used triazoles in agriculture.” Triazoles are utilized as antifungal medications, despite the rise of resistant infections, in addition to their use as systemic pesticides on many fruit and vegetable crops, including grapes, wheat, corn, and soybeans.   As Beyond Pesticides’ previous coverage indicates, many triazole fungicides in the U.S. are registered for use despite evidence of endocrine disruption established over a decade ago in a U.S. Geological Survey report. These pesticides exhibit common mechanisms of toxicity often disregarded in U.S. Environmental Protection Agency (EPA) risk assessments, with a multitude of studies showcasing the myriads of health threats that the agency does […]

(Beyond Pesticides, February 25, 2025) A literature review of over 90 scientific articles in Agriculture documents microplastics’ (MPs) increase in the bioavailability, persistence, and toxicity of pesticides used in agriculture. The interactions between MPs and pesticides enhance the threat of pesticide exposure to nontarget organisms, perpetuates the cycle of toxic chemical use, and decreases soil health that is vital for productivity. “The increasing presence of MPs in agricultural ecosystems has raised concerns about their impact on pesticide bioavailability, efficacy, and environmental behavior,” says study author Kuok Ho Daniel Tang, PhD, a global professor in the Department of Environmental Science at the University of Arizona. He continues, “These synthetic particles interact with pesticides through adsorption and desorption processes, altering their distribution, persistence, toxicity, and uptake by plants and other organisms.” Microplastics in the Environment As Beyond Pesticides has previously reported, microplastics are ubiquitous and threaten not only human health but all wildlife in both aquatic and terrestrial ecosystems. The universal distribution of plastics means that they cannot be avoided. Humans and other organisms take up plastics in the form of microparticles and nanoparticles by inhalation, ingestion, and skin contact every day. Microplastics are about the width of a human hair; nanoplastics […]

(Beyond Pesticides, February 24, 2025) The sweeping firing of federal workers, including an estimated 200,000 probationary employees (under one to two years of employment), will have a broad impact on programs to protect health and safety as well as the environment, leaving a critical need for local and state government to fill some of the gaps in critical programs, where possible. A headline in Science magazine warns, “Mass firings decimate U.S. science agencies,” and the dean of the College of Agricultural Sciences at Oregon State University told Oregon Public Broadcasting, “We’ve lost half of our teams, and all of these up-and-coming young scientists. . .so it’s like we’ve lost the next generation of scientists in agriculture and natural resources.” The same applies to important positions across the federal government, affecting every aspect of work necessary to protect public health and biodiversity and address the climate crisis. In response to President Trump’s executive orders and actions, there has been, as The New York Times reports, “new lawsuits and fresh rulings emerging day and night,” raising what experts fear may become a constitutional crisis. With the upheaval in the federal government, attention turns to the importance of state and local policies and […]

(Beyond Pesticides, February 11, 2025) In a Science of The Total Environment study, scientists test over 100 blue tit (Cyanistes caeruleus) and great tit (Parus major) birds’ nests for pesticide residues in comparison with the number of dead offspring and unhatched eggs within the nest. Fur-lined nests, from animals treated with ectoparasitic chemicals, expose birds to compounds that can impact reproductive success. The authors found fipronil, a phenyl pyrazole insecticide, in all nests, with the majority also containing the neonicotinoid insecticide imidacloprid and synthetic pyrethroid insecticide permethrin. The data shows higher insecticide levels are linked to increased offspring mortality and threaten biodiversity. This study highlights an important exposure route that is overlooked. “Although not all bird species use fur for nest building, a substantial number do, especially cavity-nesting species,” the researchers share. “Previous research found that 74% of studied woodland bird species in central Europe incorporated fur into their nests.” Many bird species in the U.S. also line their nests with fur, such as black-capped chickadees, tufted titmice, and chipping sparrows. While there is a wide body of science showing reproductive effects from pesticides, the researchers highlight the study’s novel design, saying, “To the best of our knowledge, no previous […]

(Beyond Pesticides, January 29, 2025) A team of researchers recently discovered the benefits of using natural biofertilizers and biostimulants in the production of tomatoes, the results of a two-year study featured in the Journal of the Science of Food and Agriculture. When the researchers added a biofertilizer consisting of fungi and bacteria, and/or a biostimulant made of algae, the tomato plants grew bigger, faster, and produced significantly more (and sweeter) fruit than plants that received neither treatment. This research, published in August 2024, adds to a growing body of evidence that non-synthetic, natural fertilizer alternatives can support a global transition away from the toxic chemical treadmill of modern commercial farming.  [A note about the definition of plant biostimulants. They are substances or microorganisms that enhance natural plant processes, improving resource efficiency, stress tolerance, and overall growth without directly providing nutrients or controlling pests. There is ongoing confusion regarding a lack of a set definition, as some biostimulants overlap in function with fertilizers or biocontrol agents. The definition of biofertilizers—also referred to as inoculants, bioinoculants, or bioformulations—are products containing beneficial microorganisms in active or inactive forms. These microorganisms, applied singly or in combination, colonize the rhizosphere or plant tissues to enhance […]

(Beyond Pesticides, January 24, 2025) Based on data collected from government sources and independent monitoring, a multidisciplinary team of researchers at the University of Connecticut finds that 46% of Connecticut waterway samples are contaminated with levels of the neonicotinoid insecticide, imidacloprid—one of the most widely used insecticides in the United States on lawn and golf courses. The authors relied on federal data from U.S. Environmental Protection Agency (EPA) and U.S. Geological Survey (USGS), state-level data from Connecticut Department of Energy and Environmental Protection (CT-DEEP), and a small-scale data collection study by the Clean Rivers Project funded by the nonprofit Pollinator Pathway, Inc. In their report, Neonicotinoids in Connecticut Waters: Surface Water, Groundwater, and Threats to Aquatic Ecosystems, the researchers provide the most comprehensive view to date of neonicotinoid levels in Connecticut and offer critical recommendations for future testing within the state and nationally, given glaring data gaps. It is important to note that the authors acknowledged early in the report the “abandonment” of Integrated Pest Management in “the use of neonicotinoids has coincided with and been implicated in the decline of many non-target species of insects, in particular pollinators such as bees () and monarch butterflies.” They point out that […]

(Beyond Pesticides, January 21, 2025) When the American Cancer Society (ACS) published its annual report last week, it pointed to a rising incidence of cancer in younger women and highlighted disparities by race and ethnicity that are especially timely with the commemoration of Dr. Martin Luther King, Jr. In its report, “Cancer Mortality Continues to Drop Despite Rising Incidence in Women; Rates of New Diagnoses Under 65 Higher in Women Than Men,” ACS writes: “Disparities in cancer occurrence and outcomes are often the result of socioeconomic deprivation as a consequence of structural racism, which limits opportunities for education and other mechanisms of upward mobility. For example, the historical practice of mortgage lending discrimination known as redlining is associated with later stage cancer diagnosis, lower likelihood of receiving recommended treatment, and higher cancer mortality. Inequalities in wealth lead to differences in the prevalence of risk factor exposures as well as access to high-quality cancer prevention, early detection, and treatment. Even beyond higher prevalence of common risk factors like smoking and obesity, exposure to carcinogenic air emissions is up to 50% higher among people experiencing poverty, regardless of race or ethnicity. In 2022, 25% of AIAN [American Indian and Alaska Native] people lived below the federal […]

(Beyond Pesticides, January 17-20, 2025) Martin Luther King Day recognizes the achievements of a remarkable civil rights leader while asking the nation to assess what more the country must do to ensure equality and environmental justice, as well as protection for those who suffer disproportionately from toxic chemical exposure. Advocates and disproportionately affected communities acknowledge the historic nature of the Biden Administration’s commitment to elevating environmental justice in the decision-making of the U.S. Environmental Protection Agency (EPA). However, according to Willy Blackmore, writer for Minnesota Spokesman-Recorder (“the oldest Black-owned newspaper in the state of Minnesota and one of the longest-standing, family-owned newspapers in the country”), “[T]he more systemic change that [Administrator] Regan’s EPA tried to bring about was stonewalled by legal challenges that threatened to undermine the agency’s strongest tool for righting environmental injustices.” Black communities across the nation face disproportionate impacts to petrochemical infrastructure and toxic chemicals, including pesticides and fertilizers. A 2021 study published in BMC Public Health found that biomarkers for 12 dangerous pesticides tracked over the past 20 years were found in the blood and urine of Black participants at average levels up to five times those in White participants. A University of Michigan study found […]

(Beyond Pesticides, January 14, 2025) Women with occupational pesticide exposure have elevated rates of breast cancer, according to a study in Immunopharmacology and Immunotoxicology. Based on an analysis of clinicopathological data from 188 affected women, the study authors demonstrate “that occupational exposure to pesticides modifies the clinical presentation of disease in breast cancer patients, depending on their age at disease onset, affecting cytokine production, especially in those exhibiting early age at diagnosis.”   “Breast cancer (BC) is the most common malignant neoplasm affecting women worldwide and the second leading cause of cancer-related death in this population,” the researchers report. They continue: “Aging is the primary risk factor associated with breast cancer development and mortality, resulting in a cumulative lifetime risk of 1 in 8 women developing the disease. Disease onset significantly impacts patient prognosis. While most cases are of late onset and occur in women over 50 years of age, early-onset BC is prevalent in certain populations and is associated with a poor prognosis and aggressive tumor behavior.”  Data was collected and analyzed from May 2015 to December 2022, with the study population in Brazil spanning “27 municipalities in the southwest of Paraná, a region characterized by extensive pesticide use, predominantly […]

(Beyond Pesticides, December 24, 2024 – January 1, 2025) We wish you a healthy and happy holiday season! The health and environmental challenges that we face as families and communities across the nation and worldwide require us to stay engaged. The stark reality of the challenges ahead energizes us at Beyond Pesticides to strengthen our program—now, more than ever!   And, we trust that you, like us, want to push forward for a livable future. In this context, please see our annual report and summary on the important work that we are doing, and please consider a contribution to Beyond Pesticides during this holiday season.  While the threats of health, biodiversity, and climate crises grow exponentially, the solutions we have advocated for decades are now within reach. We know how to produce food and manage land without petrochemical pesticides and fertilizers, as organic food is widely available. Beautiful parks, playing fields, and schoolyards do not require toxic chemical use. At the same time, the regulatory system underperforms, as existential health and environmental problems escalate.   And, we know that individual steps that we take to stay healthy, as important as they are, cannot protect us and the natural world, on which […]

(Beyond Pesticides, December 19, 2024) As The New York Times reported last month, the government in South Africa declared a national emergency—23 children died and nearly 900 people were sickened from pesticide poisoning in Johannesburg’s Soweto township. The illnesses and fatalities have been traced to small amounts of highly neurotoxic pesticides, including the insecticides terbufos and aldicarb, found in local food items. These chemicals, described by South African President Cyril Ramaphosa as “street pesticides,” are being increasingly used (legally and illegally) for pest infestations in the townships and informal settlements of South Africa’s poorest communities, where poverty and inadequate waste collection exacerbates the pest management challenges. Without formal electricity, running water, or municipal garbage collection, many residents rely on highly toxic pesticides for pest infestations in their homes and makeshift markets, resulting in food inadvertently being contaminated with pesticides.  The announcement highlights the dangers of allowing these highly toxic agricultural chemicals to be used in farming, with tragic consequences for vulnerable communities when they are diverted for use in urban settings. This tragic situation also draws attention to the elevated threat that pesticides pose when stringent enforcement mechanisms are not in place to ensure compliance with pesticide restrictions, even with […]

(Beyond Pesticides, December 13, 2024) In October, the U.S. Environmental Protection Agency (EPA) approved the registration applications of BASF Corporation and Mitsui Chemicals Crop & Life Solutions, Inc. for the use of different formulations of the L-isomer of glufosinate (also known as “L-glufosinate” and “glufosinate-P”) as new active herbicidal ingredients. This decision marks one of the first times that EPA has employed its new Herbicide  Strategy Framework to determine the level of mitigation necessary to protect listed species and critical habitat under the Endangered Species Act (ESA). Glufosinate is an organophosphate, with known neurotoxic, reproductive/developmental effects, toxic to aquatic life, and mobile in soils (see Beyond Pesticides Gateway). Scientists have found that formulated glufosinate is generally more toxic to aquatic and terrestrial animals than the technical grade active ingredient. Manufacturers are introducing newer glufosinate products as alternatives for glyphosate-based herbicides, like Bayer/Monsanto’s ‘Roundup’ and dicamba. The Center for Biological Diversity notes in comments submitted to EPA on this decision, “L-glufosinate has the potential to be used on tens of millions acres of land every year given the crops EPA has proposed to register it on. The scale of potential use is far above most new active ingredients.” This first significant application […]

(Beyond Pesticides, December 5, 2024) A novel, comprehensive study published in Science reviews a library of 1,024 different chemicals (herbicides, insecticides, fungicides, and plant inhibitors) finding that, even at “sublethal” exposure levels, 57% of tested chemicals impact the behavioral and physiological health of house fly larvae. Mosquito and butterfly populations are also susceptible to long-term adverse effects at sublethal levels. Environmental and public health advocates continue to raise concerns about adverse effects resulting from the failure of the U.S. Environmental Protection Agency (EPA) to consider cumulative exposure (resulting in aggregate and synergistic effects) across different mechanisms of toxicity and different classes of pesticides, including at exposure levels below allowable levels set by the agency. In the context of the regulatory gaps and pesticide industry influence at EPA (See Daily News here), advocates stress the importance of transitioning land and agricultural practices to organic principles. Methodology and Results  Background, Goals, Primary Takeaways  This research was led by an international team of experts from various universities and institutes, including European Molecular Biology Laboratory (EMBL), Institut Pasteur, and Heidelberg University (Center for Infectious Diseases, Parasitology Department). The authors received funding from the European Molecular Biology Laboratory, the German Center for Infection Research, and […]

(Beyond Pesticides, November 8-11, 2024) On Veterans Day 2024 we honor those who have served the country and allies. In the 117th (2021-2022) U.S. Congress, legislators enacted The Sergeant First Class Heath Robinson Honoring Our Promise to Address Comprehensive Toxics Act of 2022 (PACT Act). Since the law passed just over two years ago, there has been just under 1.3 million total approved claims marking a roughly 75% approval rate for PACT Act related claims, according to Department of Veteran Affairs (VA) accounting of progress between August 10, 2022, and October 12, 2024 through its dedicated bimonthly VA PACT Act Performance Dashboard. The legacy of toxic burn pits (open air areas where the military has burned toxic waste) and other avenues for toxic exposure in military bases oversees, as well as within the United States in Hawai’i (See coverage on asbestos exposure continuously impacting veterans, as reported on by Honolulu Civil Beat) and Puerto Rico (See peer-reviewed literature review here on toxic heavy metals in International Journal of Environmental Research and Public Health), among other areas, comes at a time when the country assesses the ongoing impacts of a history that has been characterized by critics as colonial or imperialist. […]

(Beyond Pesticides, November 5, 2024) Published in the journal Frontiers in Toxicology, a recent study uncovers serious flaws in the pesticide registration process at the U.S. Environmental Protection Agency (EPA) with an in-depth evaluation of the agency’s failure to protect the public from the harmful effects of five neonicotinoid (neonic) insecticides—as mandated by the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) and amendments, including Food Quality Protection Act (FQPA) of 1996. This coincides with EPA’s ongoing review to renew their approval for the next 15 years (set to be announced in 2025). The report is based on the first comprehensive assessment of unpublished rodent-based Developmental Neurotoxicity (DNT) studies, conducted between 2000-2003 and submitted by pesticide manufacturers as part of the registration process. All five neonicotinoids evaluated—acetamiprid, clothianidin, imidacloprid, thiacloprid, and thiamethoxam—are associated with significant shrinkage of brain tissue at the highest dosage, according to EPA data reports (see acetamiprid, clothianidin, imidacloprid, thiacloprid, and thiamethoxam). However, with little or no data regarding the chemicals’ impacts at low and mid-level dosages, EPA has either failed to find a “No Observed Adverse Effect Level” (NOAEL) or, seemingly at random, set the NOAEL at the mid-level dosage. The evaluation suggests that perinatal exposure to […]