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Daily News Blog

Archive for the 'Breast Cancer' Category


29
Sep

EPA Reverses on Decision to Ban Flea Collars with Toxic Pesticide, Leaving Children at Risk

(Beyond Pesticides, September 29, 2023) In unsurprising news, the Environmental Protection Agency (EPA) has reversed itself and decided not to ban a dangerous pesticide: tetrachlorovenphos (TCVP) used in pet flea collars and other flea products. This is despite its own earlier decision to ban TCVP in pet collars and scathing criticism of its methods and conclusions by the courts. First registered in 1966, TCVP belongs to the notoriously toxic organophosphate chemical family and is classified by the World Health Organization as “possibly carcinogenic to humans.” It was originally registered to Shell Chemical, then to E.I. duPont de Nemours, then to Hartz Mountain Corporation and Fermenta Animal Health Company.  Early on, it was registered for use on food crops and livestock, but the crop uses were voluntarily de-registered in 1987. It is still widely used on pets and farm animals. In 1995, EPA issued the opinion that “all uses of tetrachlorvinphos, with the exception of oral feed-through larvicide treatment to livestock intended for food use, will not cause unreasonable risk to humans or the environment.” Since then, the agency has contorted itself repeatedly to allow TCVP to remain on the market. There is little research available on TCVP’s human health effects; the […]

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21
Sep

All Pesticide Classes Increase the Risk of Central Nervous System Tumors in Children

(Beyond Pesticides, September 21, 2023) A literature review published in CiĂŞncia & SaĂşde Coletiva finds environmental exposure to all classes of pesticides (fungicides, herbicides, insecticides) has an association with childhood astrocytoma (brain/central nervous system [CNS] tumor). CNS tumors represent half of all malignant neoplasms (tumors) in children. Although medical advancements in disease survival are progressing, childhood cancer remains the leading cause of death from disease among children. Furthermore, childhood cancer survivors can suffer from chronic or long-term health complications that may be life-threatening. The etiology or cause of childhood cancer involves the interaction of multiple components that include environment, lifestyle and genetics. However, emerging evidence indicates that environmental contaminants like pesticides (e.g., occupational exposures, air pollution, pesticides, solvents, diet, etc.) affect disease etiology. Pesticide contamination is widespread in all ecosystems, and chemical compounds can accumulate in human tissues, resulting in chronic health effects. Children are particularly vulnerable to the impacts of pesticide exposure, as their developing bodies cannot adequately combat exposure effects. Moreover, several studies demonstrate an association between environmental or occupational pesticide exposure and the risk of childhood cancer. Considering that maternal pesticide exposure can have a stronger association with cancer among children than childhood exposure, and newborns can still encounter pesticides, it is […]

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11
Aug

Study Cites Multiple Chemical Characteristics, Strengthening Weed Killer Glyphosate Cancer Ranking

(Beyond Pesticides, August 11, 2023) Reinforcing earlier findings, a systematic review published in Chemosphere finds the popular herbicide glyphosate and its formulations (glyphosate-based formulations-GBF) exhibit five out of the ten key characteristics (KC) of carcinogens (cancer-causing chemicals). Specifically, glyphosate exhibits strong evidence of genotoxicity, epigenetic alterations (heritable changes in gene expression), oxidative stress, chronic inflammation, endocrine disruption, and disturbs gut microbiota implicated in lymphomagenesis (growth and development of lymphoma). Although organizations like the International Agency for Research on Cancer (IARC) designate glyphosate as a probable human carcinogen, and scientific literature supports the findings on these adverse effects purported by glyphosate, the chemical remains on the U.S. market in various formulations. Glyphosate is the most commonly used active ingredient worldwide, appearing in many herbicide formulas, not just Bayer’s (formerly Monsanto) Roundup®. The use of this chemical has been increasing since the inception of crops genetically modified to tolerate glyphosate over two decades ago. The toxic herbicide readily contaminates the ecosystem with residues pervasive in food and water commodities. In addition to this study, literature proves time and time again that glyphosate has an association with cancer development, as well as human, biotic, and ecosystem harm. Therefore, advocates point to the need for national policies to reassess hazards associated with […]

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07
Jul

Pesticide Lobby Pushes Farm Bill Amendment to Strip Localities and States from Restricting Pesticides

The introduction of the Agricultural Labeling Uniformity Act in the U.S. House of Representatives, expected to be a part of the Farm Bill negotiations, is raising the specter (yet again) of undermining local and state authority to protect the health of their residents from pesticides—effectively overturning decades of Supreme Court precedent.

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29
Jun

Industrial Chemical Giants in PFAS Water Contamination Case Agree to $1.185 Billion Settlement

(Beyond Pesticides, June 29, 2023) In the first major settlement amid an influx of PFAS litigation, industrial chemical giants DuPont, Chemours, and Corteva will pay $1.185 billion dollars to cities and towns across the U.S. to cover the cost of PFAS remediation and monitoring in public drinking water systems. The significance of this nationwide class-action settlement cannot be overstated, as citizens have battled powerful chemical corporations for decades with limited success. Dangerous toxicants have been indiscriminately discharged into the environment by chemical companies since the mid-1900s, and the PFAS litigation is important in the company’s acceptance of responsibility for contamination. Of course, the damage to health and the environment is incalculable, given the pervasive environmental contamination and poisoning that it has caused, and additional lawsuits are pending, with more expected. Advocates maintain that this case exemplifies the inadequacies of regulatory controls that do a poor job of capturing the long-term effects of chemicals before being introduced into the market and a worse job of questioning the essentiality of toxic substances for which there are alternative practices and products. PFAS bring into sharp focus the legacy of chemical contamination and the impact on  future generations—a problem well-documented with pesticides like DDT […]

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25
May

New Viewpoint on the Historic Link between Endocrine Disrupting Chemicals and Cancer Discussed

(Beyond Pesticides, May 25, 2023) A review of scientific literature published in the Journal of Endocrinological Investigation demonstrates exposure to past and current-use endocrine-disrupting chemicals (EDCs), like pesticides, have a long history of severe adverse human health effects. Endocrine disruptors are xenobiotics (i.e., chemical substances like toxic pesticides foreign to an organism or ecosystem) present in nearly all organisms and ecosystems. The World Health Organization (WHO), European Union (EU), and endocrine disruptor expert (deceased) Theo Colborn, Ph.D., classify over 55 to 177 chemical compounds as endocrine disruptors, including various household products like detergents, disinfectants, plastics, and pesticides. Endocrine disruption can lead to several health problems, including hormone-related cancer development (e.g., thyroid, breast, ovarian, prostate, testicular), reproductive dysfunction, and diabetes/obesity that can span generations. Therefore, studies related to pesticides and endocrine disruption help scientists understand the underlying mechanisms that indirectly or directly cause infertility, among other health issues. The review notes, “New evidence supports the role of other EDCs as possibly carcinogenic and pregnant women should avoid risk area and exposure. The relationship between EDCs and cancer supports the need for effective prevention policies increasing public awareness.” The review examines the relationship between EDCs and various hormone-mediated various (i.e., breast, prostate, testicle, ovary, and thyroid) to determine the carcinogenicity of the chemicals and their impact on public […]

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18
Apr

France’s Drinking Water Contaminated with Toxic Fungicide Chlorothalonil, Banned in EU but Widely Used in U.S.

(Beyond Pesticides, April 18, 2023) Health officials in France are alerting the public that a majority of drinking water samples tested by the government contain the presence of the highly toxic fungicide chlorothalonil. The findings highlight a stark divide between regulations and public health management in the European Union and United States. While EU member states have banned this chemical and are working to understand and address lingering effects, tens of millions of pounds of chlorothalonil continue to be sprayed throughout the U.S. annually. French officials say they conducted this research after researchers in Switzerland found evidence of the fungicide in drinking water. A few years ago, Swiss scientists released a report showing Evian bottled water, touted for its claims of purity, was found to contain measurable levels of chlorthalonil.  “The fact that even the Evian springs in the French Alps, which are hardly affected by humans, contain pesticide residues is alarming and shows the far too careless handling of these substances,” Roman Wiget, president of the international drinking water association AWBR told the German-language Swiss weekly at the time. The EU banned uses of chlorothalonil in 2019, due to concerns over water contamination, the effects of such contamination on fish […]

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30
Mar

Research Further Associates Widespread Atrazine Exposure to Breast Cancer

(Beyond Pesticides, March 30, 2023) A study published in Ecotoxicology and Environmental Safety finds that the commonly used herbicide, atrazine, promotes breast cancer development through suppression of immune cell stimulation, and thus function, and upregulation of enzymes mediating tumor development. According to the Centers for Disease Control and Prevention (CDC), breast cancer is a disease that causes breast cells to grow out of control, with the type of breast cancer depending on the cells themselves. Several studies and reports, including U.S. Environmental Protection Agency (EPA) data, identify hundreds of chemicals as influential factors associated with breast cancer risk. Breast cancer is the most common cancer among women, causing the second most cancer-related deaths in the United States. Past studies suggest genetic inheritance factors influence breast cancer occurrence. However, genetic factors only play a minor role in the incidence of breast cancer, while exposure to external environmental factors (i.e., chemical exposure) appears to play a more notable role. One in ten women will receive a breast cancer diagnosis, and genetics can only account for five to ten percent of cases. There are grave concerns over exposure to endocrine (hormone) disrupting chemicals and pollutants that cause adverse health effects. Therefore, advocates point to the need for national […]

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08
Mar

Creosote-Induced Health Problems Persist from Springfield, MO Production, Now Superfund, Site

(Beyond Pesticides, March 7, 2023) An old Kerr-McGee Wood Treatment Facility is still causing health issues among residents in Springfield, Missouri. The former site of pressure-treated railroad tie production remains contaminated with creosote, a concoction of dangerous chemicals including polycyclic aromatic hydrocarbons, phenols, and creosols. While residents are still dealing with lingering effects of a now shuttered production site, the U.S. Environmental Protection Agency (EPA) is set to reregister creosote (wood preservatives are regulated as pesticides in the U.S.), perpetuating the harm caused by this material despite the wide availability of alternatives. The wood treatment facility in question operated for nearly 100 years, releasing significant levels of creosote-related chemicals throughout the immediate region. The Kerr-McGee Corporation spun off its liability for a range of hazardous sites previously under its control to a separate company called Tronox, which subsequently declared bankruptcy in 2009. Andarko Petroleum then purchased Kerr-McGee, but, during bankruptcy proceedings, Tronox filed a complaint against both Andarko and Ker-McGee, alleging fraudulent conveyance of the liabilities. As EPA explains, “At the core of the plaintiffs’ complaints is the allegation that the Defendants fraudulently transferred valuable assets out of Tronox and left Tronox with insufficient funds to pay the billions of […]

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31
Jan

Glyphosate Induces Oxidative Stress, A Cancer Precursor, According to NIH Study

(Beyond Pesticides, January 31, 2023) Glyphosate exposure induces oxidative stress in the body, a key biomarker known to heighten an individual’s risk of cancer, according to research published in the Journal of the National Cancer Institute by a team of scientists from the National Institutes of Health. The findings, which tracked study participants’ past use of glyphosate and exposure levels through urine, are particularly concerning in light of recent data showing that four out of five (81.6%) U.S. residents have detectable levels of glyphosate in their bodies. Despite these concerning data, evidence of widespread exposure to a carcinogen has so far failed to sway regulators at the U.S. Environmental Protection Agency, necessitating meaningful change by elected officials to reform pesticide regulation. Scientists began with the determination from the International Agency for Research on Cancer (IARC) that there is epidemiological evidence associating glyphosate with blood cancers like non-Hodgkin lymphoma, and strong evidence of carcinogenicity in laboratory animal research brought on by genotoxicity (DNA damage) and oxidative stress. “Oxidative stress occurs when the production of reactive oxygen species (ROS) and other free radicals exceeds the body’s antioxidant defense mechanisms, causing damage to DNA, proteins, and lipids,” the study explains. This process can […]

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03
Jan

Hazardous Fumigant in Food Production Harmful to Farmworkers, Groups Call for Ban

(Beyond Pesticides, January 3, 2023) The California Department of Pesticide Regulation (DPR) announced new rules that remove existing limits on the use of 1,3-dichloropropene (1,3-D or Telone), allowing Californians to breathe much more 1,3-D than state toxicologists in the Office of Environmental Health Hazard Assessment (OEHHA) say is safe and highlighting the dangers to which farmworkers are routinely exposed. It is outrageous that the state of California and the U.S. Environmental Protection Agency (EPA) would allow farmworkers—whose labor was judged “essential” during the pandemic—to be routinely exposed to highly toxic pesticides, which could be replaced by organic practices. While the state of California describes its action as increasing protection, advocates point to continued use, unacceptable harm, and the availability of alternative organic agricultural production methods that eliminate the use of 1,3-D. Since over a third of the country’s vegetables and three-quarters of the country’s fruits and nuts are grown in California, most people who buy their food in a grocery store have a stake in how food is grown in the state and the impact that it has on those who live and work there. Tell the state of California, U.S. EPA, an the U.S. Congress to cancel the registration […]

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13
Dec

Estrogen-Mediated Cancers in Humans Have Links to Endocrine Disrupting Pesticides

(Beyond Pesticides, December 13, 2022) Pesticides have a long history associated with hormone (endocrine)-disrupting properties that induce various molecular changes, prompting disease development. Adding to the science, a review published in Environmental Exposure, Biomonitoring and Exposure Assessment highlights how specific estrogen-mimicking pesticides increase the risk of disease, particularly hormone-related cancers among women (i.e., breast, ovarian, endometrial cancer) and men (i.e., testicular, prostate cancer). Like pesticides, endocrine disruptors are xenobiotic (i.e., chemical substances foreign to an organism or ecosystem). Many reports demonstrate that exposure to endocrine-disrupting chemicals can adversely affect human, animal—and thus environmental—health by altering the natural bodily hormones responsible for conventional reproductive, physical, and mental development. Endocrine disruption can lead to several health problems, including hormone-related cancer development (i.e., thyroid, breast, ovarian, prostate, testicular), reproductive dysfunction, and diabetes/obesity that can span generations. Therefore, studies related to pesticides and endocrine disruption help scientists understand the underlying mechanisms that indirectly or directly cause cancer, among other health issues. Pesticides are one of the most potent xeno-estrogenic compounds, as estrogenic strength and environmental half-life exceed those of other xeno-estrogenic compounds. Focusing on organochlorine pesticides (OCs), the study evaluates the chemical effects on the physiological (anatomic) system to increase cancer risk. Using human studies, researchers assessed how estrogen-medicated cancer develops in women and men. […]

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25
Nov

Hormone Mimicking Properties of Glyphosate Weed Killer and Related Compounds Increase Breast Cancer Risk

(Beyond Pesticides, November 25, 2022) A study published in Chemosphere adds to the growing body of research demonstrating the endocrine (hormone) disrupting effects of glyphosate play in breast cancer development. Exposure to the herbicide glyphosate and other glyphosate-based herbicides (GBHs) at high concentrations mimics the estrogen-like cellular effects of 17β-estradiol (E2), altering binding activity to estrogen receptor α (ERα) sites, thus causing fundamental changes in breast cancer cell proliferation (abundance).  Glyphosate is the most commonly used active ingredient worldwide, appearing in many herbicide formulas, not just Bayer’s (formerly Monsanto) Roundup®. The use of this chemical has been increasing since the inception of crops genetically modified to tolerate glyphosate over two decades ago. The toxic herbicide readily contaminates the ecosystem with residues pervasive in food and water commodities. In addition to this study, literature proves time and time again that glyphosate has an association with cancer development, as well as human, biotic, and ecosystem harm. Therefore, advocates point to the need for national policies to reassess hazards associated with disease development and diagnosis upon exposure to chemical pollutants. The researchers note, “The results obtained in this study are of toxicological relevance since they indicate that glyphosate could be a potential endocrine disruptor in the mammalian system. Additionally, […]

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10
Nov

Kids and Kidney Cancer: Implication for Prenatal Pesticide Exposure

(Beyond Pesticides, November 10, 2022) A meta-analysis by the University Alberta Hospital, Edmonton, AB, Canada, adds to the plethora of research linking prenatal (before birth/during pregnancy) pesticide exposure to carcinogenic (cancer) tumor development. The analysis, published in Human & Experimental Toxicology, finds parental exposure to pesticides during the preconception (before pregnancy) or pregnancy period increases the risk of Wilms’ tumor (a type of kidney cancer) occurrence among children. Already, studies find low levels of pesticide exposure during pregnancy or childhood cause adverse health effects, from metabolic disorders to mental and physical disabilities. Although medical advancements in disease survival are more prominent nowadays, childhood cancer remains the leading cause of death from disease among children. Furthermore, childhood cancer survivors can suffer from chronic or long-term health complications that may be life-threatening. Children are particularly vulnerable to the impacts of pesticide exposure as their developing bodies cannot adequately combat exposure effects. Moreover, a mother’s pesticide exposure can have a stronger association with cancer among a child than childhood exposure, and a newborn can still encounter pesticides. Therefore, it is essential to understand how pesticides impact the health and well-being of individuals during critical developmental periods, especially for latent diseases (e.g., cancers). The researchers performed a systematic review and meta-analysis on case-control studies […]

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27
Oct

Breast Cancer Month: Neonicotinoid Insecticides and Breast Cancer Risk (Triple Negative Breast Cancer)

(Beyond Pesticides, October 27, 2022) A study published in Environment International adds to the growing body of research evaluating the association between neonicotinoid insecticides (neonics/NIs) and breast cancer. Past studies suggest neonics act as endocrine disruptors, affecting the development and regulation of estrogen hormones that promote breast cancer. However, this study is one of the few to evaluate the toxicological and molecular mechanisms involved in initiating breast cancer events. According to the Centers for Disease Control and Prevention (CDC), breast cancer is a disease that causes breast cells to grow out of control, with the type of breast cancer depending on the cells themselves. Most common forms of breast cancer have receptors on the cell surface that can increase cancer growth when activated by estrogen, progesterone, or too much of the protein called HER2. One in ten women will receive a breast cancer diagnosis, and genetics can only account for five to ten percent of cases. When a cancer cell lacks receptors for these molecules, G protein-coupled estrogen receptors (GPERs) are an essential biological target of estrogen and plays a role in hormone-dependent cancer development. GPERs regulate estrogen through non-genetic cellular pathways, forgoing attachment to standard molecular receptors, leading to triple-negative breast cancer (TNBC). Although past […]

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24
Oct

Advocates Urge Elimination of Toxic Pesticide Use to Prevent Breast Cancer

(Beyond Pesticides, October 24, 2022) We need prevention of the causes of breast cancer, not just awareness. In 1985, Imperial Chemical Industries and the American Cancer Society declared October “Breast Cancer Awareness Month” as part of a campaign to promote mammograms for the early detection of breast cancer. Unfortunately, most of us are all too aware of breast cancer. Detection and treatment of cancers do not solve the problem. Tell EPA to evaluate and ban endocrine-disrupting pesticides, and make organic food production and land management the standard that legally establishes toxic pesticide use as “unreasonable.”  Next to skin cancer, breast cancer is the most common cancer among women, causing the second most cancer-related deaths in the United States. Genetic factors only play a minor role in breast cancer incidence, while exposure to external environmental factors such as pesticides plays a more notable role. For breast cancer, one in eight women will receive a diagnosis, and genetics can only account for five to ten percent of cases. Therefore, it is essential to understand how environmental exposure to chemicals like pesticides can drive breast cancer development. Several studies and reports, including U.S. Environmental Protection Agency (EPA) data, identify hundreds of chemicals as influential factors associated with breast cancer […]

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30
Sep

EPA’s Failure to Ban Glyphosate Keeps Burden of Protection with Consumers and Local and State Governments

(Beyond Pesticides, September 30, 2022) In late September, the U.S. Environmental Protection Agency (EPA) announced the withdrawal of its Interim Decision on glyphosate, the active ingredient in multiple herbicides, most notably Monsanto’s (now Bayer’s) Roundup. The action follows a slew of developments related to the herbicide, including: the 2015 International Agency for Research on Cancer’s declaration of its carcinogenicity; legal judgments and massive rewards to victims who developed cancers after chronic exposures; advocate efforts to get EPA to recognize the dangers of, and curtail, its use; and pushback from industry — most of the latter two coming in the form of litigation. The withdrawal of that Interim Decision means, on the ground that this harmful compound can continue to be used until a next regulatory review decision by EPA. Beyond Pesticides has long been engaged in education on and advocacy against glyphosate use, and was a plaintiff in the 2020 lawsuit, with the Center for Food Safety (CFS), et al., against EPA for this 2020 Interim Decision (ID). Under FIFRA (the Federal Insecticide, Fungicide and Rodenticide Act) each pesticide must be reviewed by EPA every 15 years “to ensure that existing pesticide products continue to perform their intended function without […]

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29
Sep

Exposure to Pesticides in the Womb Increases Risk Associated with Rare Eye Cancer Among Children

(Beyond Pesticides, September 29, 2022) A study published in the International Journal of Hygiene and Environmental Health finds an association between retinoblastoma risk and prenatal exposure to pesticides. Retinoblastoma is a rare eye cancer, with over 200,000 cases in the U.S., most of which are children under the age of five. Despite occurring among offspring, this cancer is often not hereditary. Instead, a mutation in the RB1 gene during early development in the womb destabilizes and augments cell growth. Although the etiology or cause of childhood eye cancer involves the interaction of multiple components like lifestyle and genetics, emerging evidence indicates that environmental contaminants like pesticides (e.g., occupational exposures, air pollution, pesticides, solvents, diet, etc.) play a role in disease etiology. Pesticide contamination is widespread in all ecosystems, and chemical compounds can accumulate in human tissues resulting in chronic health effects. Children are particularly vulnerable to the impacts of pesticide exposure as their developing bodies cannot adequately combat exposure effects. Already, studies find low levels of pesticide exposure during pregnancy or childhood cause adverse health effects from metabolic disorders to mental and physical disabilities. While medical advancements in disease survival are more prominent nowadays, childhood cancer remains the leading cause of death from disease among children. […]

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15
Sep

With Global Disease Rates Rising, Do Pesticides Take Some of the Blame? Science Says, “Yes.”

(Beyond Pesticides, September 15, 2022) A review published in Scientific African finds pesticide exposure contributes to the increase in non-communicable diseases (NCDs) in Tanzania, reflecting implications for global health. There are four main NCDs, including cardiovascular diseases, cancers, respiratory diseases, and endocrine-disrupting diseases like diabetes. These diseases have no bacterial, viral, or fungal causes, but are chronic diseases with risk factors like genetics, tobacco/alcohol use, physical activity, and diet, thus lacking transmission between people. However, research is now investigating the role environmental factors play in NCD risks, such as outdoor and indoor air pollution, exposure to chemicals, radiation, and occupation. Regardless of whether working together or separately, these risk factors contribute to NCDs and subsequent health conditions. Non-communicable diseases are on the rise, and the World Health Organization (WHO) classifies non-communicable diseases as the number one cause of death globally, affecting 41 million individuals. Moreover, WHO estimates NCD death rates to increase by 17 percent in the next decade, significantly surpassing deaths from communicable, maternal, perinatal, and nutritional diseases combined. Therefore, the report notes, “This review is informative to the policy, practices, and intervention towards the existing situation of pesticides in Tanzania. In addition, it calls for further investigation of the absence of data […]

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02
Sep

Compounds in Pesticides Shown to Harm Fetuses and Children with Disproportionate Risk to People of Color

(Beyond Pesticides, September 2, 2022) Revelations of toxic risks to pregnant people seem to emerge with alarming frequency. In late August a peer-reviewed study published in Chemosphere finds that the compound melamine, its primary byproduct (cyanuric acid), and four aromatic amines were detected in the urine of nearly all pregnant research participants. These chemicals are associated with increased risks of cancer, kidney toxicity, and/or developmental harm to the resultant child. Beyond Pesticides has covered a variety of pregnancy risks from pesticides and other toxic chemicals, including these in just the last three years: pesticides and children’s sleep disorders; prenatal exposures to a multitude of chemicals; insecticides and childhood leukemia; insecticides and Attention Deficit/Hyperactivity Disorder. Those of a certain age may hear “Melamine” and think of the nearly indestructible plastic dinnerware from the mid-20th century, but “melamine” is an organic chemical compound that, when combined with formaldehyde, forms a durable plastic. Others may remember the 2007–2008 incident in China of contamination of infant formula with melamine, which resulted in six deaths, and kidney and urinary tract harms (ranging from development of kidney stones to acute renal failure) in some 300,000 babies. [A small sidebar explainer: melamine was actually intentionally added to the formula […]

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26
Aug

As Thyroid Cancer Cases Rise, Study Finds Pesticides Link

(Beyond Pesticides, August 26, 2022) New research from a team in California finds one-third of pesticides it reviewed — including glyphosate, paraquat dichloride, and oxyfluorfen — to be associated with the development of thyroid cancer. Researchers investigated the links between exposure to pesticides — including 29 that cause DNA cell damage — and the risk of this cancer. The researchers also find that in all the single-pollutant models they employed, paraquat dichloride — a widely used herbicide — was linked to this cancer. In 2021, Beyond Pesticides covered research by the U.S. National Institutes of Health (NIH) that demonstrated that exposures to lindane and metalaxyl also cause heightened risk of thyroid cancer. These study findings add to the already considerable concern about pervasive pesticide exposure — not only among farmers and applicators, but also in the general population. It is worth noting that, in addition to elevated thyroid cancer risks, multiple pesticides can cause other health damage. Paraquat is also acutely toxic, and can cause longer-term reproductive, renal, and hepatic damage to humans; it is toxic to birds, fish, and other aquatic organisms, and slightly so to honeybees. Glyphosate, as Beyond Pesticides has written frequently, is carcinogenic, and is associated […]

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18
Aug

Parents’ Exposure to Pesticides Indicative of Childhood Cancer Risk among Offspring

(Beyond Pesticides, August 18, 2022) A study published in Environmental Research suggests occupational (work-related) exposure to pesticides among nonpregnant women and men may increase childhood cancer risk for offspring. Already, studies find low levels of pesticide exposure during pregnancy or childhood cause adverse health effects from metabolic disorders to mental and physical disabilities. However, few assess parental exposure’s impact on childhood disease risk outside critical development periods (e.g., pregnancy). Although medical advancements in disease survival are more prominent nowadays, childhood cancer remains the leading cause of death from disease among children. Furthermore, childhood cancer survivors can suffer from chronic or long-term health complications that may be life-threatening. The etiology or cause of childhood cancer involves the interaction of multiple components like lifestyle and genetics. However, emerging evidence indicates that environmental contaminants like pesticides (e.g., occupational exposures, air pollution, pesticides, solvents, diet, etc.) play a role in disease etiology. Pesticide contamination is widespread in all ecosystems, and chemical compounds can accumulate in human tissues resulting in chronic health effects. Children are particularly vulnerable to the impacts of pesticide exposure as their developing bodies cannot adequately combat exposure effects. Moreover, several studies demonstrate an association between environmental or occupational pesticide exposure and the risk of childhood cancer. Considering maternal pesticide […]

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26
Jul

Inspector General Finds Secret EPA Meetings with Industry and Use of Untested Science to Lower Cancer Risk for Dangerous Fumigant

(Beyond Pesticides, July 26, 2022) Secret meetings with industry, the elevation of unqualified individuals to decision-making roles, using an untested scientific approach, failing to conduct a simple literature review, and an overall absence of public transparency. This is how the U.S. Environmental Protection Agency’s (EPA) conducted its cancer review for the potent fumigant pesticide 1,3-Dichloropropane (1,3-D; brand name: Telone), according to a report from EPA’s Office of Inspector General (OIG). EPA’s actions allowed a product once considered to pose a 1 in 10,000 risk of cancer to Americans to increase exposure by 9,000% (from 7.7 ÎĽg/m3 to 690 ÎĽg/m3). “These departures from established standards during the cancer assessment for 1,3-D undermine the EPA’s credibility, as well as public confidence in and the transparency of the Agency’s scientific approaches, in its efforts to prevent unreasonable impacts on human health,” the OIG report states. Yet, even with the agency’s failings laid out in clear view, EPA’s lackluster response to OIG’s corrective actions in this case add insult to its injurious actions against public health. OIG initiated a review of EPA’s cancer assessment for 1,3-D after the submission of multiple complaints. 1,3-D is a highly toxic fumigant used on a variety of crops, […]

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