(Beyond Pesticides, April 27, 2022) Pesticides can accumulate in aquatic fly larvae, be retained through metamorphosis, and represent a source of chronic pesticide exposure to birds and bats, according to research published in Environmental Science and Technology earlier this month. As population declines among these critical wildlife continue to mount, findings like these highlight the complex ways in which human activities are further stressing natural systems. Pesticide reviews conducted by the U.S. Environmental Protection Agency (EPA) are limited to an outdated set of studies conducted by the pesticide industry, and generally reject and dismiss emerging science from independent literature. This myopic focus on industry studies has brought widespread contamination to the natural world that necessitates wholescale changes at EPA through Congressional action. With widespread acknowledgement that older pesticide chemistries, such as organochlorines like DDT and aldrin, bioconcentrate in living organisms, researchers aimed their study at present use fungicides and herbicides that have not yet undergone similar scrutiny. This includes seven fungicides—azoxystrobin, boscalid, cyflufenamid, fluopyram, tebuconazole, pyrimethanil, and trifloxystrobin—and two herbicides—napropamide and propyzamide. The study notes that formulated end use products, rather than technical grade active ingredients, were used in order to best mimic real world exposure conditions. Larvae of the […]

(Beyond Pesticides, April 20, 2022) A University of Michigan study is the first to highlight that maternal pesticide exposure during pregnancy adversely affects sleeping patterns for offspring later in life, specifically for females. Prenatal development is one of the most vulnerable periods of exposure as the fetus is most susceptible to the harmful effects of chemical contaminants. Many studies indicate that prenatal and early-life exposure to environmental toxicants increases susceptibility to diseases, from learning and developmental disabilities to cancer. However, the toxicity of pesticide exposure ad its full impact on the nonagricultural population in the U.S., especially women. Given research links to sleep-related disorders and neurological and cognitive development, studies like this can help government and health officials identify how pesticides’ impact on the brain elevates health concerns. The authors note, “Overall, these results are of public health importance considering the continued widespread agricultural and possibly residential use of pyrethroids and chlorpyrifos [in Mexico]…Thus, our results underline the importance of additional research studies that include both larger samples and assessment of unregulated pesticides, as well as studies that consider the underlying mechanisms explaining sex differences.” Levels of inadequate sleep patterns are rising among children and adolescents. Reports find variability in sleep duration results in higher rates of depression, anxiety, and […]

(Beyond Pesticides, April 5, 2022) A meta-analysis by the Federal University of Technology – Paraná finds the herbicide 2,4-D causes indiscriminate harm, increasing the mortality rate among exposed animals. The severity of chemical exposure relies on species sensitivity, exposure rate, and lifecycle stage. However, commercial formulations of 2,4-D, commonly used in the environment, prompt a higher species mortality rate than technical (pure) 2,4-D alone. Like many other common herbicides such as glyphosate, 2,4-D has global uses that allow the chemical to accumulate in the environment, including soils, waterways, and tissues of non-target species. Therefore, meta-analyses like this help local and government officials make holistic decisions regarding environmental contaminants that incorporate conclusions from various studies. Using the Web of Science and Scopus databases, researchers compiled various studies (or meta-analyses) on the lethality of 2,4-D in different animal species (e.g., vertebrates, invertebrates). Researchers evaluated each study regarding the mortality rate of control and experimental groups, animal sensitivity to chemical exposure during a specific life stage, chemical formulation (e.g., commercial or technical), and exposure routes causing mortality. The analysis demonstrates that vertebrates experience higher mortality rates from 2,4-D exposure, with fish and birds presenting the highest mortality rate. Regarding life stages, larval and adult […]

(Beyond Pesticides, March 23, 2022) A study published in Nature Reviews Earth & Environment warns that thawing of permafrost (a ground that remains completely frozen for two or more years) in the Arctic region can prompt the reemergence of greenhouse gases (e.g., methane and carbon dioxide), microbes, and chemicals (e.g., banned pesticides like DDT). Past research finds gases, microbes, and chemicals drift near the poles, becoming entrapped in ice under the accumulating snowfall. As the global climate continues to rise and the climate crisis worsens, studies like this show significant effects, as ice encapsulating these toxic chemicals is melting. Upon melting, some chemicals can volatilize back into the atmosphere, releasing toxicants into the air and aquatic systems, with the ensuing consequences. Microbes frozen for thousands to millions of years can also emerge from thawing permafrost, with unknown implications on human, animal, and ecosystem health. The melting permafrost is already beginning to impact infrastructure, creating sinkholes that damage roads, trees, and utility poles. Moreover, mixtures of chemicals, microbes, and greenhouse gases (GHGs) in permafrost are difficult to assess. Therefore, studies like this highlight the need to evaluate the health and ecological effects of melting arctic permafrost (and glaciers) from anthropogenic (human)-induced climate change. […]

(Beyond Pesticides, February 28, 2022) When bacteria and fungi become resistant to pesticides, it is a signal that the toxic chemical approach to controlling pathogens does not work. But resistance also poses a direct threat to human health when the pesticide (or a related chemical) is used in human medicine. Tell EPA to cancel all uses of a pesticide when resistance is discovered or predicted to occur. Tell Congress to ensure that EPA protects public health from deadly antifungal and antibiotic resistance. The threat of resistance in bacterial human pathogens has long been widely recognized. Although research sponsored by the Environmental Protection Agency (EPA) recognizes the spread of resistance to antibiotics important in human medicine through horizontal gene transfer in the environment, EPA inaction both on antibiotic and antifungal resistance has become a growing crisis. EPA does recognize the existence of resistance to fungicides. It uses codes produced by the Fungicide Resistance Action Committee in decisions regarding fungicide registration. Although EPA says resistance “may be considered in the risk-benefit decision-making process,” there is no evidence that the agency actually considers the failure of EPA-registered pesticides to control the target organisms in registering pesticides. That failure has a serious impact on […]

(Beyond Pesticides, February 18, 2022) A new analysis conducted by Safer States, and reported on by Environmental Health News (EHN), concludes that in 2022, at least 32 states will consider 210 potential laws to ban or restrict one category of so-called “legacy” chemicals — the PFAS (per- and polyfluoroalkyl substances) family of compounds. “Legacy” or “forever” chemicals are those whose historical use, including many decades ago in some instances, has led to their toxic persistence in the environment and in organisms. In recent years, scientists, health and environment advocates, and policy makers have begun to recognize these as very serious contaminants, and to call attention to their ubiquity and impacts. Beyond Pesticides has identified multiple instances of such “legacies” (including those related to the production of pesticides and particularly, the infamous DDT), and will here discuss both PFAS, and concerns about such legacy chemicals as they may impact food producers. The term “legacy” often connotes the ongoing influence or impact — generally salutary — of an individual’s activity, or a set of principles or activity inherited from one’s forebears. It is an apt description, minus the “salutary” part, for legacy chemicals — toxic “gifts that keep on giving” via persistent contamination […]

(Beyond Pesticides, February 11, 2022) A team of researchers has proffered a potential, biotechnical, way forward in the quest to reduce the scourge of malaria, which affects many people across the world. Their work uses the relatively new “Crispr” technique to address, and reverse, the growing problem of mosquito resistance to the pesticides that currently dominate control strategies for the insects that spread the disease. This innovation nevertheless raises concern about both the introduction of new, genetically altered organisms into the environment without sufficient information on the implications, and continued, intensive pesticide use. Beyond Pesticides recognizes, as do the researchers, that malaria-borne mosquitoes pose a serious public health problem; however, it advocates for alternatives to chemical approaches to managing the spread of the disease, and asserts that successful management strategies will contend with the underlying conditions that exacerbate that spread. In 2020, Executive Director Jay Feldman said, “We should focus on the deplorable living conditions, and inequitable distribution of wealth and resources worldwide that give rise to squalor, inhumane living conditions, and the poor state of development that, together, breed insect-borne diseases like malaria.”     Malaria, which is spread by female Anopheles mosquitoes infected with a Plasmodium parasite, causes illness in more than 200 million people annually, and is lethal to more than 400,000, […]

(Beyond Pesticides, February 4, 2022) In January, the U.S. Department of Agriculture (USDA) issued its 30th Pesticide Data Program (PDP) Annual Summary report (which evaluates each year the presence of pesticide residues on produce) and misleads the public on the safety of food and agricultural practices. This 2020 report concludes that more than 99% of the produce samples tested showed residues below established U.S. Environmental Protection Agency (EPA) benchmark levels. At first blush, this sounds very reassuring, but Beyond Pesticides maintains that there is (always) more to the “safety” story, not least of which are serious deficiencies in EPA’s establishment of those “tolerances.” Those flaws include a lack of risk assessment for vulnerable sub-populations, such as farmworkers, people with compromised health, children, and perhaps, cultural/ethnic and regional sub-groups of the general population, and a failure to fully assess serious health outcomes such as disruption of the endocrine system (which contributes to numerous serious diseases). For everyone, Beyond Pesticides recommends choosing organic produce whenever possible — the vast majority of which does not contain synthetic pesticide residues. The PDP report asserts that “the data . . . illustrate that residues found in agricultural products sampled are at levels that do not pose […]

(Beyond Pesticides, January 12, 2022) Well water in agricultural regions of Sri Lanka is contaminated with highly hazardous insecticides and associated with a decline in kidney function, according to research published in npj Clean Water this month. This finding is the latest piece in an ongoing ‘puzzle’ regarding the epidemic of chronic kidney disease of unknown origins in Sri Lanka and other developing countries in agricultural regions. Although the exact etiology of the disease has not been confirmed, a number of scientific studies have pointed the finger at industrial agriculture, increasingly finding evidence of chronic pesticide exposure in affected populations.   To better understand the connection between agrichemical exposure and kidney health, researchers enrolled 293 individuals from Wilgamuwa, Sri Lanka into a prospective study. Baseline data was retrieved on occupational and environmental exposure factors, focusing in on the water source individuals used at their homes. Samples of each participant’s household wells were taken and analyzed for the presence of pesticides. Of the wells sampled, 68% were found to contain pesticides. Further, every well where pesticides were detected had at least one pesticide recorded above global drinking water guidelines. The chemicals found were also some of the most toxic pesticides to […]

(Beyond Pesticides, December 16, 2021) A study by Shanghai Jiao Tong University, China, finds Parkinson’s Disease (PD) risk increases with elevated levels of organochlorine (OCP) and organophosphate (OP) pesticides in blood. Among patients with PD, specific organochlorine compounds have greater associations with cognitive impairments, including depression and brain function. Research finds exposure to chemical toxicants, like pesticides, can cause neurotoxic effects or exacerbate preexisting chemical damage to the nervous system. Although the mechanism by which pesticides induce disease development remains unclear, researchers suggest changes in protein enzyme composition and cellular dysfunction from pesticide exposure interrupt normal brain function. Parkinson’s disease is the second most common neurodegenerative disease, with at least one million Americans living with PD and about 50,000 new diagnoses each year. The disease affects 50% more men than women, and individuals with PD have a variety of symptoms, including loss of muscle control and trembling, anxiety and depression, constipation and urinary difficulties, dementia, and sleep disturbances. Over time, symptoms intensify, but there is no current cure for this fatal disease. While only 10 to 15 percent of PD incidences are genetic, PD is quickly becoming the world’s fastest-growing brain disease. Therefore, research like this highlights the need to examine alternate […]

(Beyond Pesticides, November 18, 2021) A study published by King George’s Medical University, India, finds exposure to xenobiotic substances like pesticides during pregnancy increases risks associated with preterm birth, including a rise in cesarean section (C-section) deliveries and a decrease in fetal body weight. Preterm births occur when a fetus is born early or before 37 weeks of complete gestation. Premature births can result in chronic (long-term) illnesses among infants from lack of proper organ development and even death. Birth and reproductive complications are increasingly common among individuals exposed to environmental toxicants, like pesticides. The Center for Disease Control (CDC) reports the preterm birth rate is increasing annually. Therefore, studies like this can help government and health officials safeguard human health by assessing adverse effects following prevalent chemical exposure. The study notes, “To the best of our knowledge, this was a pioneering study, and it may help to increase our knowledge with regard to xenobiotic exposure in biological systems and the need for stringent guidelines for agricultural use of pesticides.” The study examines the association between the transfer of xenobiotics (foreign synthetic substances like pesticides) from mother to fetus. Transferal of these toxic substances can result in biological and chemical changes (i.e., genotoxicity […]

(Beyond Pesticides, November 12, 2021) Omnivorous readers may have encountered an article, in the November 15 issue of The New Yorker magazine, titled — at best misleadingly, and certainly sensationally — “The Great Organic-Food Fraud.” The subhead comports with the tone of the headline: “There’s no way to confirm that a crop was grown organically. Randy Constant exploited our trust in the labels — and made a fortune.” The piece, by Ian Parker, tells a complex tale of the machinations of dishonest and greedy people who saw, in the commerce in organic grains, an opportunity to misrepresent nonorganic crops as organic and make a boatload of money in doing so. What the article fails to do is render any comprehensive picture of how National Organic Program certification and inspection work, and the underlying principles, values, and standards in federal law (the Organic Foods Production Act), nor does it review either the benefits of organic agriculture broadly or the massive harmful impacts of conventional, chemical-intensive agriculture in the U.S. Beyond Pesticides provides ballast, in this Daily News Blog article, to the failings of the New Yorker article and the damage it might do to the organic movement. It is worth noting […]

(Beyond Pesticide, November 4, 2021) A scientific literature analysis by the Federal University of Goias, Brazil, finds occupational (work-related) exposure to agricultural pesticides increases the risk for 45 different types of cancer. This analysis assesses studies from the last decade—2011 to 2020—to identify cancer risk associated with occupational exposure by country, pesticide type, and methods used to diagnose disease. Many pesticides are “known or probable” carcinogens (cancer-causing agents), and widespread uses only amplify chemical hazards, adversely affecting human health. However, research on cancer and pesticides lacks comprehensive information regarding human health effects associated with long-term chemical use. This study highlights the significant role that long-term research plays in identifying potential health concerns surrounding registered pesticides. The use of these xenobiotics (foreign chemical compounds) substances in agriculture are increasing. Thus, it is important those working with and around these toxicants have protection. The analysis notes, “Overall, then, the results of the present study emphasize the need to evaluate overuse of pesticides and the concomitant increase in the number of cancer cases. Future research should thus include active intervention in the correct use of pesticides by farmworkers and encourage adequate training and the use of PPEs [personal protective equipment], as well as routine periodic medical […]

(Beyond Pesticides, October 21, 2021) A study published in Environment International finds higher rates of various cancers among agricultural workers, with multiple myeloma (blood cancer) and melanoma (skin cancer) disproportionately impacting female farmers. Although research studies link cancer risk to genetic and external factors (e.g., cigarette smoke), there are increasing reports and scientific studies that pesticide exposure augments the risk of developing common cancers like melanoma and less common cancers like multiple myeloma. This study highlights the importance of understanding how pesticide use can increase the risk of latent diseases, which do not immediately develop upon initial exposure. The researchers note, “Given the large size of the agricultural population worldwide and the presence of various potential hazards in its working environment, such epidemiological data are important in improving occupational health measures and ensuring better workers’ health.” To investigate the cancer incidence patterns, researchers evaluated data from the AGRICOH database involving various international studies. The studies assessed pesticide exposure scenarios, which researchers use to determine the etiological (causal) agent of cancer incidences among farmers relative to the general population. Researchers analyzed data from eight different AGRICOH groups in various countries: France (AGRICAN), the U.S. (AHS, MESA), Norway (CNAP), Republic of Korea (KMCC), Denmark […]

(Beyond Pesticides, September 16, 2021) A study published in Chemosphere finds persistent organic pollutants (POPs), including organochlorine pesticides (OCPs), polychlorinated biphenyls (PCBs), and polybrominated diphenyl ethers (PBDEs), are present in the serum and placenta of pregnant mothers, as well as multiple fetal organs. Many studies indicate prenatal and early-life exposure to environmental toxicants increases susceptibility to diseases, from learning and developmental disabilities to cancer. However, this study is one of the first to demonstrate the presence of chemical toxicants in fetal tissue that are not present in maternal serum or placental samples. Prenatal development is one of the most vulnerable periods of exposure when the fetus is most susceptible to the harmful effects of chemical contaminants. Therefore, studies like these help government and health officials better identify fetal exposure contaminants and subsequent health concerns otherwise missed by current chemical monitoring methods. The researchers note, “These findings call for further evaluation of the current matrices used to estimate fetal exposure and establish a possible correction factor for a more accurate assessment of exposure in utero. We disclose the full data set on individual exposure concentrations to assist in building in silico models for prediction of human fetal exposure to chemicals.” Several studies associate early-life exposure to toxic chemicals […]

(Beyond Pesticides, September 2, 2021) A McMaster University (Canada) study demonstrates exposure to the recently banned, commonly used insecticide chlorpyrifos promotes obesity development, even at low doses. Obesity generally occurs following a caloric imbalance between food intake, absorption, and energy expenditure. Although various factors can promote obesity, researchers suggest environmental toxicants like chlorpyrifos play a role in obesity development through protein/enzyme suppression. According to the Center for Disease Control, 42 percent of the U.S. population is obese and at risk for type two diabetes, cardiovascular (heart) disease, stroke, several cancers, and other critical health issues. Therefore, research like this highlights the significance of investigating how toxic chemical exposure can impact health to prevent adverse disease outcomes. Researchers note, “These studies suggest that the effects of environmental toxicants on the development of obesity may have been underestimated as all studies to date have been conducted in mice housed at RT [room temperature]. Future studies examining the mechanisms driving reductions in β-AR [beta adrenergic receptors] signaling and whether there are associations between BAT [brown adipose tissue] metabolic activity and CPF [chlorpyrifos] in humans will be important.” Several environmental pollutants have links to obesity development via the effects on gut health, endocrine (hormone) and metabolic system, […]

(Beyond Pesticides, September 1, 2021) A study published in Environmental Pollution finds the risk of acute childhood leukemia (AL) increases with prenatal and newborn exposure to pesticides (i.e., insecticides and herbicides). The study results support the hypothesis that chronic environmental pesticide exposure increases childhood leukemia risk up to two times. Maternal exposure has a stronger association with leukemia than childhood exposure. Insecticides and herbicides are of particular significance in increasing leukemia risk, especially for acute lymphoblastic leukemia. Although medical advancements in disease survival are more prominent nowadays, childhood AL remains the secondary cause of child mortality following physical injury. Furthermore, childhood leukemia survivors can suffer from chronic or long-term health complications that may be life-threatening. Although the etiology or cause of childhood AL involves the interaction of multiple components like lifestyle and genetics, emerging evidence indicates that environmental contaminants like pesticides (e.g., occupational exposures, air pollution, pesticides, solvents, diet, etc.) play a role in disease etiology. Pesticide contamination is widespread in all ecosystems, and chemical compounds can accumulate in human tissues resulting in chronic health effects. Children are particularly vulnerable to the impacts of pesticide exposure as their developing bodies cannot adequately combat exposure effects. Already, studies find low levels of pesticide exposure during […]

(Beyond Pesticides, August 19, 2021) Does a science-based, public health-oriented, occupational safety focused, children-concerned, ecologically protective society allow the use of toxic pesticides that are unnecessary to achieve land management, quality of life, and food productivity goals? Should victims of poisoning have to plead with regulators to protect them? Should organizations have to fight chemical-by-chemical to achieve basic levels of protection from individual neurotoxic, cancer causing, endocrine disrupting pesticides? Of course not. But, the U.S. Environmental Protection Agency’s (EPA) announcement that it is stopping food uses of the insecticide chlorpyrifos after being registered 65 years ago provides us with an important opportunity for reflection, not just celebration. The collective effort to remove this one chemical is a tremendous feat in eliminating one exposure to a hazardous material for children. That is the point. The action we’re celebrating required an amazingly resource-intensive effort at a time in history when we are running against the clock in an urgent race to transition our society and global community away from the use of petroleum-based, toxic pesticides—to move to meaningful practices that sustain, nurture, and regenerate life. In this context, let’s put chlorpyrifos in perspective. EPA was forced into its decision by a court […]

(Beyond Pesticides, August 12, 2021) A recent study published in Chemosphere identifies the concentration, consequences, and potential sources of 22 organochlorine pesticides (OCPs) among corals in the South China Sea (SCS) for the first time. SCS corals exhibit a higher affinity toward bioaccumulation of OCPs, which are legacy persistent organic pollutants (POPs) under the Stockholm Convention—a global treaty to eliminate POPs. The study finds the distribution of OCPs in coral tissue matches that of the surrounding oceanic air samples. Hence, atmospheric concentrations of OCPs—influenced by continental air masses—migrate from the atmosphere to seawater through gas exchange. Coral reefs are one of the largest ecosystems in the ocean, sustaining marine biodiversity and providing many goods and services. However, living coral populations are rapidly declining due to ocean acidification, oceanic warming, habitat destruction, and pollution from human activity across the globe. From rare corals off the coast of Florida to well-established hard corals in the Great Barrier Reef, these communal organisms are sensitive to various environmental stressors that threaten biodiversity. Although several studies demonstrate the volatile, toxic nature of POPs, much less research evaluates the impact POPs have on biodiversity over time. The globe is currently going through the Holocene Extinction, Earth’s 6th mass extinction, with one million species of plants and […]

(Beyond Pesticides, August 5, 2021) A recent report by Turtle Rescue of the Hamptons finds Long Island, New York turtles are experiencing higher rates of deadly aural abscesses or ear blisters from pesticide use. Previous research documents the role chemical exposure from environmental toxicants play in inner ear abscess formation among turtles. However, synergism (collaboration) between viral infection and toxic chemical exposure increases aural abscess instances. Considering these infections are taking a toll on the Long Island turtle population, government and wildlife officials must assess how chemical exposure promotes disease development to safeguard human, animal, and environmental health. Karen Testa, executive director of Turtle Rescue of the Hamptons, cautions, “I’m urging Long Islanders to think about how these pesticides are negatively impacting the natural world. Is your perfect green lawn worth the life of a turtle?” Aural abscesses are painful ear blisters that can grow as big as a golf ball. Medical intervention is necessary to remove abscesses from turtles and treat them with an antibiotic regimen to prevent death. Turtle Rescue facility workers report a staggering 50 percent of turtles currently within their care to have aural abscesses. The percentage of turtles with this diagnosis is much higher than in past years. […]

(Beyond Pesticides, July 22, 2021) A new study published in the Journal of Medical Entomology finds black-legged ticks (Ixodes scapulari) in New York are developing potential resistance to widely used tick-control pyrethroid insecticide, permethrin. The study suggests continuous use of area-wide, 4-poster devices (devices that attract deer and then apply pesticide to their head, ears, and neck) to apply insecticide treatments on deer to control tick populations promotes resistance. Resistance is an ever-present issue among chemical compounds (i.e., antibiotics, antimicrobials, pesticides) used in medicine and agriculture, and threatening the ability to prevent disease outbreaks, such as Lyme disease. Furthermore, increasing populations of rodent and mammalian hosts, in addition to warmer temperatures prompted by the climate crisis, allows for disease-carrying ticks to flourish. Lyme disease is the most common vector disease and a primary concern for the general population. Therefore, studies like this highlight the need to assess resistance among disease-vector pest populations regardless of pesticide application methods. The researchers note, “Permethrin susceptibility of tick populations should be monitored from other 4-poster control areas so that guidelines for managing pesticide resistance in the field can be developed.” Four-poster devices impart selective pressure on tick populations influencing reproduction and natural extinction of species. However, like mosquitoes, a subpopulation of ticks […]

(Beyond Pesticides, July 9, 2021) The investigative online publication The Intercept has turned its attention to the current and historical role of industry in distorting, undermining, and outright suppressing the protective function of the U.S. Environmental Protection Agency (EPA) with regard to pesticide exposures. The subsequent reporting — “The Department of Yes: How Pesticide Companies Corrupted the EPA and Poisoned America” — is a devastating chronicle of the theme and particulars that Beyond Pesticides has covered for years. That is, that EPA has repeatedly disregarded its charge to protect human and environmental health in favor of enabling industry to continue its chemical experimentation on the populace and on the nation’s multiple natural resources. This pattern must change if the agency is to enact its mission and the public is to be protected. The Intercept interviewed more than 24 people with expertise on the regulation of pesticides, including 14 who have worked in EPA’s Office of Pesticide Programs (OPP). The chief takeaway from those interviews, as written by reporter Sharon Lerner, is that EPA “is often unable to stand up to the intense pressures from powerful agrochemical companies, which spend tens of millions of dollars on lobbying each year and employ many […]

(Beyond Pesticides, July 1, 2021) Yellow fever mosquitoes (Aedes aegypti) are evolving resistance to the pyrethroid insecticide permethrin, according to a study published by Colorado State University, highlighting the need to adopt ecologically-based mosquito management. Widespread, intensive use of the pesticide in mosquito control has allowed genetic mutations to persist among these mosquito populations, causing subsequent resistance to permethrin. Pyrethroids are one of the few remaining classes of insecticides available to control yellow fever mosquitos, and resistance threatens the ability to prevent disease outbreaks with chemical-intensive methods. Yellow fever mosquitoes are a vector for numerous untreatable diseases in humans, including dengue, chikungunya fever, and Zika viruses. Hence, this study highlights the significance of addressing pest resistance to pesticide control, particularly to mitigate disease exposure and effects. The researchers note, “This knowledge can help scientists understand how mosquitoes have evolved resistance and when a population can no longer be controlled with permethrin. This understanding will be necessary to develop tools to support future insecticide management strategies.” Researchers sequenced the genome of resistant and knockdown (either recovered or dead) mosquitoes after permethrin exposure using a bottle bioassay. The aim was to identify genomic variants/biomarkers associated with specific resistance mechanisms. Two common pyrethroid resistance mechanisms occur among […]