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As Artificial Intelligence Gains Momentum with Dramatic Promises, Bioethicists Call for Regulation

Friday, April 11th, 2025

(Beyond Pesticides, April 11, 2025) In a new report by Save our Seeds Foundation on Future Farming, a consortium of EU-based scientists and bioethicists raise concerns about the implications and threats of generative artificial intelligence (GAI) for genetic engineering. Artificial intelligence will impact all aspects of society, including the acceleration of genetic editing tools that may lead to increased risks of harmful traits/genetic data being incorporated into products on the global marketplace. Organic farmers, conservationists, and public health professionals who collaborate with Beyond Pesticides grow increasingly concerned about the long-term impacts of deregulation and ongoing federal funding freezes and firings on needed regulatory oversight of the tech sector, including AI. Review of Save our Seeds Report So, what is artificial intelligence (AI)? AI is a broad field that focuses on building machines and systems that can think, learn, and solve problems—incorporating elements of human behavior. It powers things like voice assistants, self-driving cars, and recommendation systems on apps like Netflix or Spotify. In short, AI is designed to understand information, make decisions, and complete tasks intelligently. Generative AI, however, is an extension of AI focused on creativity. The main goal is to generate new content—whether in writing, photography, video, music, […]

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Historical Programs To Address Environmental Justice Being Undone by Trump Administration

Wednesday, April 9th, 2025

(Beyond Pesticides, April 9, 2025) On March 12, 2025, the U.S. Environmental Protection Agency (EPA) Administrator Lee Zeldin announced the agency would be shutting down the Environmental Justice and Diversity, Equity, and Inclusion (DEI) offices and staff at ten of the regional offices and the headquarters in Washington, D.C. Administrator Zeldin declared that this move implemented President Donald Trump’s Executive Order, “Ending Radical and Wasteful Government DEI Programs and Preferencing.” In response to this decision, ten Democratic U.S. Senators—led by Senator Alex Padilla (D-CA) and including Senators Richard Blumenthal (D-CT), Cory Booker (D-NJ), Tammy Duckworth (D-IL), Edward J. Markey (D-MA), Jeff Merkley (D-OR), Bernie Sanders (I-VT), Adam Schiff (D-CA), Chris Van Hollen (D-MD), Sheldon Whitehouse (D-RI), and Ron Wyden (D-OR)—co-sponsored the Empowering and Enforcing Environmental Justice Act of 2025 to Congress that would codify funding for environmental justice offices in the Department of Justice. (See Sen. Padilla’s press release here.) Senators Duckworth and Booker—founding co-chairs of the Senate Environmental Justice Caucus—also issued the following statement: “Underserved communities in rural, urban and tribal areas already shoulder the brunt of the climate crisis and environmental injustice. These cuts and reversals will make it even harder for these communities to address some of […]

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Literature Review of Over 200 Studies Highlights Pesticide Threats to Women’s Reproductive Health

Tuesday, April 8th, 2025

(Beyond Pesticides, April 8, 2025) A comprehensive literature review in Environment & Health analyzes evidence from human biomonitoring, epidemiological studies, and toxicological studies that link adverse effects on women’s reproductive health, specifically impacting the ovary, to pesticide exposure. In examining the scientific literature, consisting of over 200 studies performed in the last 25 years, the authors find pesticide exposure threatens women’s health through ovarian dysfunction. “Epidemiological studies have shown that pesticide exposures are associated with early/delayed menarche [first occurrence of menstruation], menstrual cycle disorders, early menopause, long time to pregnancy, polycystic ovary syndrome, primary ovarian insufficiency, infertility, and implantation failure in women,” the researchers state. They continue, “Both in vivo [in animals] and in vitro [in cells] studies have shown that exposure to pesticides disrupts the estrous cycle, reduces the follicle pool, alters hormone levels, and impairs oocyte [egg] maturation.” These reproductive implications are noted with many different classes of pesticides, such as insecticides, including organochlorine pesticides (OCPs), organophosphates (OPs), pyrethroids, and neonicotinoids, as well as herbicides and fungicides. The authors, however, comment on present research gaps: “Much of the available epidemiological evidence focuses on legacy insecticides, such as OCPs, and a subset of insecticides that are still in use […]

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Study Finds Reproductive System Effects in Adolescents with Prenatal Pesticide Exposure

Wednesday, April 2nd, 2025

(Beyond Pesticides, April 2, 2025) In examining prenatal residential proximity of documented pesticide spraying in California to the menstrual cycle characteristics of 273 Latina adolescents, researchers report in the American Journal of Epidemiology a positive association between exposure to the insecticide methomyl and heavy bleeding. Other pesticides appear to influence menstrual symptoms as well. “Adolescents’ menstrual cycle characteristics can be â€vital signs’ of health and impact quality of life,” the authors share. They continue, “To our knowledge, this is the first study to examine the association between prenatal pesticide exposure and menstrual outcomes in adolescents of any demographic group.” Menstrual cycle characteristics, such as dysmenorrhea (painful or uncomfortable menstrual cramps), irregularity, and heavy menstrual bleeding, can also be indicators of underlying health conditions, including endometriosis, polycystic ovary syndrome (PCOS), thyroid dysfunction, and bleeding disorders. By associating the pesticide exposure of mothers during pregnancy to impacts on their children, the researchers highlight important health risks for women and young girls that are often disregarded. “The prenatal period is a critical period of reproductive development that may be particularly sensitive to endocrine disruption,” the researchers share. As previously reported by Beyond Pesticides, endocrine-disrupting chemicals are any synthetic or natural compounds that hinder […]

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Multi-Billion Verdict Against Bayer/Monsanto in GA as Legal Rights Under Attack in the State and Nationwide

Tuesday, April 1st, 2025

(Beyond Pesticides, April 1, 2025) With the second largest award of nearly $2.1 billion (see reporting on largest), a jury in Georgia state court on March 21 found the pesticide manufacturer Bayer/Monsanto guilty of causing a man’s non-Hodgkin’s lymphoma after use of the company’s glyphosate-based weedkiller RoundupTM product. The jury’s award includes $65 million in compensatory and $2 billion in punitive damages, as reported by the Associated Press and Courtroom View Network. This verdict in Barnes v. Monsanto (2025) comes amid a concerted effort by Bayer and other chemical and agribusiness groups to take away the main legal argument, “failure-to-warn,” for the type of litigation that pesticide exposure victims have commonly used to hold companies accountable. This is happening as Governor Brian Kemp of Georgia considers signing into state law a pesticide immunity bill that will prevent future litigation like this in the state. In a deregulatory environment, the courts and state governments are viewed as critical backstops, given the dismantling of the U.S. Environmental Protection Agency’s (EPA) regulatory apparatus and extremely limited Congressional oversight. History of Litigation Bayer has lost almost all of the cases filed against it for compensation and punitive damages associated with the plaintiffs’ charge that […]

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Sampling Finds Pesticides Throughout Environment with Toxic Mixtures from Agricultural Use

Friday, March 28th, 2025

(Beyond Pesticides, March 28, 2025) The Rhine Valley in southwestern Germany is renowned for the agricultural bounty it has provided for centuries. Today, the area is home to dense wine, vegetable, fruit, and cereal cultivation. However, a study shows that current regulation of pesticides, even in the relatively progressive European Union, is inadequate to protect humans and all the other organisms that produce the environment necessary for human life and civilization.  The study goal was to determine how far—and which—pesticides traveled beyond the croplands of vegetables, fruit orchards, and cereals, as well forested lands, into nontarget areas that should serve as refugia for plants, animals, and invertebrates not considered pests. Based at the Landau Institute for Environmental Sciences at the University of Kaiserslautern-Landau, the researchers used innovative methods to measure the types, concentrations, and distribution of pesticides. They took samples from three landscape categories—vegetation, topsoil, and surface water—at 78 sites distributed along six transects, each reaching from the valley floor to the tops of the mountains on either side. Samples were taken from grasses, shrub leaves, and topsoils along each transect, together with water samples from rivers, small streams, ponds, and puddles. They tested for 93 current-use pesticides (CUPs). There […]

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Flying Through States, Industry Seeks To Stop Lawsuits Over Failure to Warn of Pesticide Dangers

Wednesday, March 26th, 2025

(Beyond Pesticides, March 26, 2025) State legislation to quash lawsuits against chemical manufacturers because of their “failure to warn” about the hazards of their pesticide products is moving forward in seven state legislatures (Iowa, Missouri, Idaho, Florida, North Dakota, Tennessee, and Oklahoma) across the United States. After three bills failed to pass (Mississippi, Wyoming, and Montana) and one bill is awaiting signature into law by the Governor’s Office (Georgia), Beyond Pesticides, working with a broad coalition, is pushing back. (See Beyond Pesticides’ Failure to Warn resource hub, background materials, and opportunities for action.) If adopted, the “immunity from litigation” legislation would set a dangerous precedent for state common law claims against any manufacturers of products with toxic ingredients. Currently, pesticide labels under federal and state law generally do not warn of potential chronic effects, such as cancer, reproductive effects, infertility, birth defects, Alzheimer’s and Parkinson’s disease, diabetes, cardiovascular damage, and more (see Pesticide-Induced Diseases Database), but warn of acute effects, such as rashes, headaches, stinging eyes, and more. After years of large jury awards, preemptive settlements, and lost appeals in cases involving exposure to the weedkiller glyphosate, Bayer/Monsanto is trying to stop the company’s financial hemorrhaging with a state-by-state strategy […]

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Mexico Rejects U.S. Forcing Genetically Engineered Corn on Country under Trade Agreement

Friday, March 21st, 2025

(Beyond Pesticides, March 21, 2025) Sin maĂ­z, no hay paĂ­s – “Without corn, there is no country” (Mexican saying) In the face of U.S. efforts to require Mexico, under a trade agreement, to import genetically engineered corn, last week the Mexican legislature approved a constitutional amendment identifying native corn as “an element of national identity” and banning the planting of GE seeds. This brings to a head a clash over issues of food sovereignty and security, genetic integrity, health protection, and environmental safety. In 2020, the Mexican government committed to phasing out the importation of genetically engineered (GE) corn by 2024. Mexico had also planned to ban by April 1, 2025, the weed killer glyphosate, integral to GE corn production—but recently delayed its decision. These actions by Mexico triggered vigorous pushback by the U.S., resulting in the formation of a panel under the U.S.-Mexico-Canada Agreement (USMCA) to decide which country was in the right. The USMCA, negotiated in 2018 during President Trump’s first term, replaced the North American Free Trade Agreement. Under USMCA, parties can adopt measures to protect human animal or plant life or health. However, in December 2024, the USMCA panel ruled in favor of the U.S., rejecting […]

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Kenya Court Rules Against GMO Corn Imports, Major Win for Food Sovereignty

Wednesday, March 19th, 2025

(Beyond Pesticides, March 19, 2025) In a major win for small-scale food producers and peasant farmers in Kenya, “the Kenya Court of Appeal blocked the Kenyan government from importing genetically modified organisms (GMOs) into the country[,]” according to a press release by Alliance for Food Sovereignty in Africa (AFSA)—an alliance of organizations and movements across the continent advocating for agroecology and food sovereignty.  “We celebrate this ruling as a major victory for small-scale farmers across Kenya,” said David Otieno, a small-scale farmer and member of the Kenyan Peasants League, a social movement consisting of consumers, farmers, pastoralists, and fishers rallying against the multinational corporate takeover of food systems in Kenya. Mr. Otieno continued: “GMOs are not the solution to food insecurity in our country. Instead, they deepen dependency on multinational agribusinesses, threaten biodiversity, and compromise farmers’ ability to control their food systems.” Genetically engineered seeds are designed to be resistant to commonly used pesticides, including the weedkiller glyphosate, which locks farmers into dependence on multinational corporations rather than their own ability to practice seed saving and enhance their food sovereignty. This battle for control over the ownership of land and seeds in Kenya resonates with the growing movement of consumers, […]

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Celebrating the Life of Joan Dye Gussow, Champion of Local, Organic Food Systems

Friday, March 14th, 2025

(Beyond Pesticides, March 14, 2025) Beyond Pesticides celebrates the life and legacy of Joan Dye Gussow, EdD, a leader in the organic and local food movements for decades. Dr. Gussow passed away at 96 years young on Friday, March 6, at her home in Rockland County, New York. As the matriarch of the “eat locally, think globally” movement (New York Times), Dr. Gussow embodied what it means to practice what you preach with decades of experience in pesticide-free, regenerative organic gardening, where she grew seasonal produce for her own consumption. In her book, The Feeding Web, Gussow explains why gardening matters: “Food comes from the land. We have forgotten that. If we do not learn it again, we will die….Are we not, in fact, more helpless than any people before us, less able to fend for ourselves, more cut off from sources of nourishment? What would we do if we could not get to the supermarket?” Dr. Gussow represents the values of community- and people-first organic principles in food and land management systems. By 1971, the year after she published her first book on the relationship between nutrition and children’s performance in school, Dr. Gussow was invited to testify before […]

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Catastrophic Harm to Women from Pesticides Drives Call for Their Elimination

Monday, March 10th, 2025

(Beyond Pesticides, March 10, 2025) Following International Women’s Day, celebrated on March 8, 2025, the poignant findings on women, gender, and hazardous substances in a United Nations report raise critical issues of concern and cause for urgent action to phase out petrochemicals. The Report of the Special Rapporteur on the implications for human rights of the environmentally sound management and disposal of hazardous substances and wastes, by Marcos Orellana, was delivered to the 79th Session of the United Nations General Assembly in July 2024. Excerpts from the report follow: “Women make up roughly 60 to 70 per cent of the agricultural labour force in developing countries where pesticides and pesticide handling are especially poorly regulated. In Zambia, for example, two thirds of the labour force is engaged in agriculture, and 78 per cent are women farmers and peasants. Women there play a significant role in pesticide application, often without any or adequate personal protective equipment, especially during activities such as weeding, harvesting, and washing pesticide-laden clothes.” “In higher-income countries, women who do agricultural work are often poor and/or migrants; pesticides are one of many dimensions of marginalization and damage to their well-being. The European agriculture sector uses many seasonal and […]

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On International Women’s Day, Pesticide Risks to Women’s Health Call for Urgent Transition to Organic

Friday, March 7th, 2025

(Beyond Pesticides, March 7, 2025) In honor of International Women’s Day on Saturday, March 8, 2025, Beyond Pesticides sheds light on the disproportionate risks to women from toxic chemicals that are often unaccounted for and even dismissed throughout pesticide regulatory review and the underlying statutes. In a roundup of Daily News coverage in 2024, as well as the most recent scientific studies in 2025, on the scientific links between pesticide exposure and adverse effects in women, this article highlights the growing inequities in pesticide threats to women’s health.  Women farmers and farmworkers are particularly excluded when assessing pesticide risks. As previously reported by Beyond Pesticides, a study published in Occupational and Environmental Medicine finds that pesticide exposure, especially during puberty, can play a role in ovarian cancer development among female farmers. Although there are many studies that evaluate the risk for cancers among farmers, very few scientific articles cover the risk of ovarian cancer from pesticide exposure.  Additionally, this study suggests the role of hormones in ovarian cancer prognosis and development, highlighting an association with endocrine disruption. Endocrine disruption can lead to numerous health problems in multiple organ systems, including hormone-related cancer development (e.g., thyroid, breast, ovarian, prostate, testicular), reproductive […]

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Public and City Council Protect Organic Land Management Ordinance Against Weakening Amendment

Thursday, March 6th, 2025

(Beyond Pesticides, March 6, 2025) A proposed change to a model pesticide ordinance in the city of Portland, Maine was soundly defeated on Monday, March 3 after public engagement and a near-unanimous city council vote. In a 6-1 vote, the council rejected the school district’s request for a waiver under the city’s pesticide use ordinance to use the insecticide chlorantraniliprole/acelepryn (diamide insecticide). A campaign to reject the waiver was led by Avery Yale Kamila, cofounder of Portland Protectors, and supported by Beyond Pesticides. Portland passed a landmark Pesticide Use Ordinance in 2018 and a synthetic fertilizer ban over five years later. As stated in Beyond Pesticides testimony to the council, “Key to [the Portland ordinance’s] passage was an understanding that Portland was not going to take a product substitution approach to land management, replacing a toxic pesticide with an “organic” pesticide, but that it was facilitating the adoption of an organic systems approach that used allowed inputs (defined in the ordinance) when necessary.” The ordinance refers to allowed materials under federal organic certification law. The Landcare Advisory Committee, created by Portland’s ordinance, recommended the toxic pesticide use waiver with some objections, raising questions among city council members about the need […]

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Children’s Health Threatened as Rates of Pediatric Cancers are Linked to Agricultural Pesticide Mixtures

Tuesday, March 4th, 2025

(Beyond Pesticides, March 4, 2025) A study in GeoHealth of pediatric cancers in Nebraska links exposure to agricultural mixtures with the occurrence of these diseases. The authors find statistically significant positive associations between pesticide usage rates and children with cancer, specifically brain and central nervous system (CNS) cancers and leukemia. “Our study is the first to estimate the effect of an agrichemical mixture on the pediatric cancer rate in Nebraska,” the study authors share. “One significant advantage of our study is that we identified the pesticide consistently applied over 22 years in Nebraska counties and then estimated the overall mixture effect of these pesticides on pediatric cancer.” The elevated effect of pesticide mixtures, a reality that is not evaluated in the U.S. Environmental Protection Agency’s (EPA) pesticide registration program, was reported in Oecologia (2008), documenting harm to amphibian populations even if the concentration of the individual chemicals is within limits considered acceptable. (See additional coverage here.) There is a wide body of science highlighting the disproportionate risk of adverse health effects in children with pesticide exposure. Their small size and developing organ systems, propensity to crawl and play near the ground, tendency for frequent hand-to-mouth motion, and greater intake of […]

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Glyphosate Weed Killer Contaminates Stem Cells, Is Linked to Blood Cancers and DNA Damage, Study Finds

Thursday, February 27th, 2025

(Beyond Pesticides, February 27, 2025) In analyzing current scientific literature and data on glyphosate-based herbicides (GBHs), a research article in Environmental Sciences Europe finds that glyphosate (GLY) persists in bones before reentering the bloodstream. The mechanisms in which GLY interacts with important cells for development, called hematopoietic stem cells (HSCs), and breaks and rearranges DNA offer a possible explanation for the heightened risk of cancer, specifically blood cancers like non-Hodgkin lymphoma (NHL), myeloma, and leukemia. “Existing data on GLY/GBH metabolism and genotoxicity provide critical insights into how exposures may be contributing to blood cancers,” according to the study’s author, Charles Benbrook, PhD. Dr. Benbrook continues: “A significant portion of GLY reaching blood moves quickly into bone marrow and then bone, where it can bioaccumulate and persist… Data reviewed herein suggest that a portion of the GLY excreted by most people on a daily basis can be traced to the shedding of calcium-GLY complexes in bone back into the blood supply.” This allows for near-constant contact between glyphosate molecules and hematopoietic stem cells, which are immature cells that can develop into any type of blood cell. Mutations in hematopoietic stem cells can cause blood cancers to emerge. Those at disproportionate risk […]

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Trump Administration’s Dismantling of Federal Environmental and Public Health Programs Shifts Focus to States

Monday, February 24th, 2025

(Beyond Pesticides, February 24, 2025) The sweeping firing of federal workers, including an estimated 200,000 probationary employees (under one to two years of employment), will have a broad impact on programs to protect health and safety as well as the environment, leaving a critical need for local and state government to fill some of the gaps in critical programs, where possible. A headline in Science magazine warns, “Mass firings decimate U.S. science agencies,” and the dean of the College of Agricultural Sciences at Oregon State University told Oregon Public Broadcasting, “We’ve lost half of our teams, and all of these up-and-coming young scientists. . .so it’s like we’ve lost the next generation of scientists in agriculture and natural resources.” The same applies to important positions across the federal government, affecting every aspect of work necessary to protect public health and biodiversity and address the climate crisis. In response to President Trump’s executive orders and actions, there has been, as The New York Times reports, “new lawsuits and fresh rulings emerging day and night,” raising what experts fear may become a constitutional crisis. With the upheaval in the federal government, attention turns to the importance of state and local policies and […]

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Exposure to Glyphosate Herbicide Adversely Affects Perinatal Health, Study Finds

Thursday, February 20th, 2025

(Beyond Pesticides, February 20, 2025) Researchers at the University of Oregon found that the rollout of genetically engineered corn in the early 2000s, followed by exponential increases in glyphosate-based herbicides, “caused previously undocumented and unequal health costs for rural U.S. communities over the last 20 years.” Their results “suggest the introduction of GM [genetically modified] seeds and glyphosate significantly reduced average birthweight and gestational length.” The conclusions of this study emerge as fossil fuel advocates, including President Donald Trump, are mobilizing to pioneer “energy dominance” despite the market movement toward renewable energy. Just as chemical-intensive farmers and land managers continue to spray synthetic fertilizers and pesticides, a successful rollout of alternatives must rely on feeding the soil rather than the plant. Advocates continue to demand that elected officials and regulators embody the precautionary principle and scientific integrity in decision-making. Given the hostile federal climate on anything relating to holistic solutions, communities are coming together to move beyond input-dependent land management systems and adopt organic criteria of allowed and prohibited substances, mandatory public comment process, independent third-party certification, and a federal advisory board (National Organic Standards Board) consisting of farmers, environmentalists, consumers, scientists, economists, researchers, and other stakeholders, with binding recommendations […]

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California Weakly Defines Regenerative, Misses Chance for Meaningful Progress

Thursday, February 13th, 2025

(Beyond Pesticides, February 13, 2025) After months of deliberations and a public comment period, the California State Board of Food and Agriculture (SBFA) on January 10, 2025, formalized a definition of “regenerative agriculture” that is being widely criticized as undermining the transition of agriculture to certified organic practices that eliminate petrochemical pesticides and fertilizers. The call for the urgent and widespread adoption of organic land management is advanced by those who see organic practices—with its focus on soil health management, a national list of allowed and prohibited substances, an enforcement system, and a prohibition on genetically engineered seeds and plants, synthetic fertility and biosolids—as the only way to effectively address the current health, biodiversity, and climate crises. Nonetheless, the Board’s recommendation, accepted by the California Department of Food and Agriculture (CDFA), loosely defines regenerative agriculture as “an integrated approach to farming and ranching rooted in principles of soil health, biodiversity, and ecosystem resiliency.” The  15-member SBFA advisory board, appointed by the governor, unanimously finalized a recommendation formally defining “regenerative agriculture,” concluding two years’ worth of workgroups and stakeholder engagement. The proposal, addressed to Secretary Karen Ross, fulfills a Board project outlined in California’s Ag Vision for the Next Decade. It […]

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Beyond Pesticides Calls for Public Comment To Stop Prohibitions on State Pesticide Hazard Warnings

Monday, February 10th, 2025

(Beyond Pesticides, February 10, 2025) With the shutting down of key federal government programs, Beyond Pesticides is urging the public to speak out, especially on issues that preserve state and local authority to protect public health and safety in the absence of adequate federal standards. In this context, the U.S. Environmental Protection Agency (EPA) is considering a petition with a proposed policy that would, if adopted, prohibit states from issuing warnings of pesticide hazards, like cancer, on product labels. EPA is taking public comment through February 20, 2025, on the petition, filed by the Republican attorneys general (AGs) of 11* states.  The petition asks EPA to prohibit “any state labeling requirements inconsistent with EPA findings and conclusions from its human health risk assessment on human health effects, such as a pesticide’s likelihood to cause cancer, birth defects, or reproductive harm.” [*The 11 states filing the petition include: Alabama, Arkansas, Georgia, Indiana, Iowa, Louisiana, Montana, Nebraska, North Dakota, South Carolina, and South Dakota.] According to Beyond Pesticides: “The only conclusion that can be derived from this petition is that the AGs do not care if the people, including farmers, of their states are harmed by pesticides, and they should not be able […]

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Study Demonstrates Health Benefits of Organic Diet Over That Consumed with Toxic Pesticides

Tuesday, February 4th, 2025

(Beyond Pesticides, February 4, 2025) Adopting a fully organic diet can reduce pesticide levels in urine within just two weeks “by an average of 98.6%” and facilitate faster DNA damage repair relative to a diet of food grown with chemical-intensive practices, according to findings from a randomized clinical trial published in Nutrire. The authors explain that their finding “is likely due to two main factors: the presence of compounds characteristic of [an organic] diet, which may have high levels of antioxidants that can protect DNA and also induce DNA repair [], and the absence or decrease in the incidence of pesticides in this type of diet, which are recognized for their genotoxic effects and have the ability to affect the genetic repair system of organisms [].” Public health professionals and affected families continue to sound the alarm on the unprecedented rates of chronic illnesses, many linked to pesticide exposure, as well as the urgency in developing solutions that acknowledge the connection to policies governing agriculture, nutrition policies, and public health. Background and Methodology The purpose of this study is to identify any relationships in health effects of chemical-intensive versus organic diets in a two week-period. More specifically, the authors say […]

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Sleep Disorders in Farmers and Farmworkers Linked to Pesticide Exposure in Study Supporting Similar Findings

Friday, January 31st, 2025

(Beyond Pesticides, January 31, 2025) A recent cross-sectional study in Heliyon highlights the link between sleep disorders in Thai farmers and pesticide exposure. The authors find pesticide exposure as an important risk factor for sleep disorders after surveying 27,334 farmers over the age of 20 who had work experience for at least five years. The importance of sleep health is reflected both physically and mentally, as studies find “sleep deficiency increase[s] mortality and various health complications, including hypertension, obesity and type 2 diabetes, cardiovascular diseases, mood disorders, and neurodegenerative disorder.” Additional studies find that these issues are compounded when sleep health is affected by environmental factors such as pesticide exposure. (See previous Beyond Pesticides’ coverage here and here.) The researchers report: “The study found a positive association of 19 individual pesticides (twelve insecticides, two herbicides, and five fungicides). Some associations demonstrated a dose-response pattern. Additionally, the study revealed that women are at a higher risk of sleep-related issues with pesticide exposure compared to males. These results not only substantiate existing literature but also unveil several new individual pesticides that may impact sleep health.” Focusing on study participants in Thailand, which is “characterized by heavy pesticide use and minimal protective measures, […]

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Multitude of Studies Find Epigenetic Effects from PFAS and Other Endocrine Disrupting Pesticides

Thursday, January 16th, 2025

(Beyond Pesticides, January 16, 2025) In Ecotoxicology and Environmental Safety, researchers highlight a multitude of studies on endocrine disrupting chemicals (EDCs) and endocrine disrupting pesticides (EDPs) showing epigenetic effects from exposure. These EDCs imitate the action of endocrine hormones and lead to gene damage and multigenerational adverse effects to health. “These chemicals can interfere with the normal functioning of target tissues by altering their response to hormonal signals, thereby affecting various physiological processes including reproduction, development, the nervous system, the immune system, and even the process of carcinogenesis [causing cancer],” according to the authors from Hebei Agricultural University and Chinese Academy of Agricultural Sciences.   In causing epigenetic modifications, the authors describe that EDCs can create changes “at the nuclear and mitochondrial DNA (nDNA and mtDNA) or RNA levels, without changing the underlying DNA sequence. These alterations modify the structure or conformation of DNA, influencing gene expression and, consequently, cellular function.” They continue, “The mechanisms of epigenetics include changes in DNA methylation, chromatin modifications and the involvement of certain noncoding RNAs.” In reviewing over 80 studies on EDCs, predominantly fluorinated compounds such as per- and polyfluoroalkyl substances (PFAS), the researchers provide a summary of linkages between pesticide exposure and the […]

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Lit Review Shows Depth of Research Linking Pesticide-Induced Effects on Immune System, Leading to Disease Outcomes

Wednesday, January 15th, 2025

(Beyond Pesticides, January 15, 2025) There is robust scientific literature that unpacks the adverse human health effects of pesticide exposure, however immunological impacts do not receive adequate attention in regulatory review processes, according to an in-depth literature review. In a piece published in Frontiers in Immunology (2024) critiquing recent peer-reviewed scientific studies, as well as unpublished research produced by the Institute of Biology and Experimental Medicine in partnership with the National Scientific and Technical Research Council in Argentina, researchers assess immune system effects of pesticide exposure, which creates the conditions for deadly health conditions including various forms of cancer. The focus of this study, according to the authors, is “to critically review fundamental aspects of toxicological studies conducted on PPPs [Plant Protection Products] to provide a clearer understanding of the risks associated with exposure to these compounds on human health.” PPPs are pesticide products that contain more than one active ingredient, and can include synergistic ingredients that supercharge them alongside inert ingredients that pesticide companies are not legally required to disclose under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), but are often manipulated biologically and chemically active. Most studies analyze the toxicological impacts of active ingredients in isolation rather […]

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