(Beyond Pesticides, December 11, 2008) In a recent study, researchers find that triclosan, the antibacterial agent found in many consumer products including soaps, toothpaste, cosmetics, counter tops and toys, alters thyroid function in male rats. These effects are observed at concentrations that may be used in consumer products and highlight the growing threat consumers face from this hazardous and ubiquitous chemical. The study, entitled, “The effects of triclosan on puberty and thyroid hormones in male wistar rats,” was reviewed by the National Health and Environmental Effects Research Laboratory, the U.S. Environmental Protection Agency (EPA) and approved for publication in Toxicological Sciences. Researchers measured blood concentrations of testosterone and several other types of hormones and weighed a variety of organs that are essential for rat development and puberty, including the pituitary gland, the testes, the prostate gland and the liver of male rat pups fed an oral dose of triclosan for 31 days. The purpose of the experiment was to determine what effects triclosan would have on concentrations of thyroid hormones and the onset of puberty. Results show a dramatic decrease in the thyroid hormone -thyroxine in rats exposed to increasing concentrations of triclosan, as well as significant increases in liver […]

(Beyond Pesticides, November 17, 2008) A toxic soup of the most commonly used pesticides frequently detected in nature can adversely affect the environment and decimate amphibian populations even if the concentration of the individual chemicals are within limits considered safe, according to University of Pittsburgh research published in the online edition of Oecologia. The results of this study build on a nine-year effort to understand potential links between the global decline in amphibians, routine pesticide use, and the possible threat to humans in the future. Amphibians are considered an environmental indicator species because of their unique sensitivity to pollutants. Their demise from pesticide exposure could foreshadow the fate of less sensitive animals, according to study author Dr. Rick Relyea, Ph.D., an associate professor of biological sciences in the University of Pittsburgh’s School of Arts and Sciences. Leopard frogs, in particular, are vulnerable to contamination; once plentiful across North America, their population has declined in recent years as pollution and deforestation has increased. Dr. Relyea exposed gray tree frog and leopard frog tadpoles to small amounts of the ten pesticides that are widely used throughout the world. Dr. Relyea selected five insecticides: carbaryl, chlorpyrifos, diazinon, endosulfan, and malathion; and five herbicides: […]

(Beyond Pesticides, November 11, 2008) Researchers at the Duke University School of Medicine have linked organophosphate pesticides to the epidemics of obesity and type 2 diabetes. The researchers specifically link neonatal low-dose parathion exposure in rats to disruption of glucose and fat homeostasis. The study, “Exposure of Neonatal Rats to Parathion Elicits Sex-Selective Reprogramming of Metabolism and Alters the Response to a High-Fat Diet in Adulthood,” was published in the November 2008 issue of Environmental Health Perspectives. It follows research by the National Institutes of Health (NIH) that links pesticide exposure to type 2 diabetes using epidemiological data from the Agricultural Health Study. Although most studies of organophosphates focus on their neurotoxicity, there is increasing evidence that these agents may also have a lasting impact on metabolic function. According to authors, obesity and consequent type II diabetes are rising at epidemic rates in the U.S. and many other countries around the world. Two of three U.S. adults are now classified as overweight. There are epidemiologic links between pesticide exposure and diabetes, and the same subpopulations that have the highest rates of obesity””inner-city, low-socioeconomic-status, agricultural populations””are also those that have greater exposure to organophosphates and other pesticides. The researchers chose parathion […]

(Beyond Pesticides, October 6, 2008) University of Pittsburgh researchers have found that the commonly used insecticide malathion can decimate tadpole populations by altering their food chain. The study, published in the October 1 edition of Ecological Applications, finds that gradual amounts of malathion that were too small to directly kill developing leopard frog tadpoles instead sparked a biological chain of events that deprived them of their primary food source. As a result, nearly half the tadpoles in the experiment did not reach maturity and would have died in nature. The results build on a nine-year effort to investigate whether there is a link between pesticides and the global decline in amphibians, which are considered an environmental indicator species because of their sensitivity to pollutants. According to the researchers, their deaths may foreshadow the poisoning of other less environmentally-sensitivespecies, including humans. According to the U.S. Environmental Protection Agency (EPA), malathion is the most commonly used insecticide in U.S. agriculture and the third most commonly used insecticide in the U.S. home and garden sector. It has been detected in the wetlands where frogs and other amphibians live. The researchers created simulated ponds from 300-gallon outdoor tanks containing wood frog and leopard frog […]

(Beyond Pesticides, September 22, 2008) A study published in the September issue of Environmental Health Perspectives finds that low-dose, short-term exposure to esfenvalerate, a synthetic pyrethroid pesticide, delays the onset of puberty in rats at doses two times lower than U.S. EPA’s stated no observable effect level (NOEL) of 2.0 mg/kg/day. Synthetic pyrethroids are used for everything from lawn care and household insecticides, to mosquito control and agriculture. There are currently 348 pesticide products registered by the U.S. EPA. The researchers conclude: “Although the exact mechanism of action is unknown at this time, we observed the effects at dosage levels below the NOEL established through chronic dietary exposure studies in rats. The U.S. EPA (1998) http://www.epa.gov/fedrgstr/EPA-PEST/1998/April/Day-29/p11372.htm stated that ”˜There is no evidence of additional sensitivity to young rats or rabbits following pre- or postnatal exposure to esfenvalerate.’ The present study shows that immature female rats exposed to 1.0 mg/kg/day are sensitive to this pesticide, as evidenced by their delay in the onset of puberty. Delayed pubertal onset in humans has been associated with low bone mass density (Ho and Kung 2005), and estrogen is necessary for bone mineral acquisition in both girls and boys (Yilmaz et al. 2005). Importantly, a […]

(Beyond Pesticides, July 17, 2008) In a new study published in Environmental Health Perspectives, researchers have found an increased occurrence of intersex toads in areas with greater agricultural land cover. This points to a link between certain pesticides and endocrine disruption, a change in the hormonal balance that can have sexual and reproductive effects. Such results implicate pesticides in the decline of amphibian populations, and suggests that these chemicals are also adversely affecting humans. The study, which was conducted in south Florida, looked at cane toads, Bufo marinus, at five sites with differing land use patterns ranging from suburban to nearly completely agricultural (primarily sugarcane and vegetables). Researchers examined physical characteristics such as coloration, sexual organs, and forelimb length, as well as hormone concentrations, and found a higher rate of feminization for toads in agricultural areas. In these areas, glyphosate (the active ingredient in Round Up herbicide) and atrazine (an herbicide) use is common. Tyrone Hayes, PhD, was one of the first to document the endocrine disrupting effects of atrazine on frogs in a laboratory setting. Countering any doubts of why this work is important, Dr. Hayes said, “People often say, ”˜It is just frogs, so who cares?’ Well it […]

*July 14, 2008 Update: Officials have reported that the cause for poisoning of these Maryland residents was jimsonweed, not pesticides. Jimsonweed was found in the garden of the home where the stew had been prepared. Symptoms are similar to organophosphate pesticide poisonings. (Source: NBC4) (Beyond Pesticides, July 10, 2008) Showing just how toxic common pesticides can be, six people in Gaithersburg, Maryland who ate potentially contaminated stew have been hospitalized with probable pesticide poisoning. Reports say that mint leaves from a backyard garden that were in a potato stew are suspected to have contained organophosphate pesticide residues. Unfortunately, the media is reporting this as a case of failing to wash produce properly, which does not address the root of the pesticide poisoning problem””that pesticides are hazardous and their uses cause harm. In fact, when EPA registers pesticides for use in food production, whether in the garden or commercial agriculture, it does not disclose or warn the public about pesticide residues or require the washing of treated food commodities, and it does not point to the availability of nontoxic alternatives. The Washington Post reports, “In a textbook illustration of the importance of thoroughly washing plants and vegetables before eating them, authorities […]

(Beyond Pesticides, June 30, 2008) The European Union’s (EU) agricultural ministers have agreed to revise pesticide restrictions across the 27-member state. The draft proposals ban pesticides that are known to cause cancer, endocrine disruption, or reproductive harm in humans, affecting up to 15 percent of currently used products. However, in “exceptional cases, when available products do not offer sufficiently effective plant protection, other hazardous substances may be used, but only under strictly regulated conditions.” The agreement’s next step is parliamentary approval, where lawmakers could make the final rule even stricter.The proposal would push farmers and chemical companies to replace the most toxic products with alternatives, remove provisional licenses for pesticides not yet registered with the EU, restrict the use of crop-dusters, and ban pesticides near sensitive areas.“One of the main aims of the proposal is to maintain a high level of protection for humans, animals and the environment. This is essential for our citizens,” said EU Health Commissioner Androulla Vassiliou, who advocated for this ban in May. “We will not authorize what is known to be harmful for public health.” Hungary, the Irish Republic, Romania, and the UK abstained from voting, citing risk of crop yields and lack of research […]

(Beyond Pesticides, June 13, 2008) A recent study by Newcastle University, published in the Journal of Science of Food and Agriculture, finds that organic farmers who let their cows graze as nature intended are producing better quality milk. The Nafferton Ecological Farming Group study finds that grazing cows on organic farms in the UK produce milk which contains significantly higher beneficial fatty acids, antioxidants and vitamins than their conventional ”˜high input’ counterparts. During the summer months, one of the beneficial fats in particular — conjugated linoleic acid, or CLA9 — is found to be 60% higher.”We have known for some time that what cows are fed has a big influence on milk quality,” explained Gillian Butler, livestock project manager for the Nafferton Ecological Farming Group at Newcastle University, who led the study. “What is different about this research is it clearly shows that on organic farms, letting cows graze naturally, using forage-based diet, is the most important reason for the differences in the composition between organic and conventional milk.“We’ve shown that significant seasonal differences exist, with nutritionally desirable fatty acids and antioxidants being highest during the summer, when the cows are eating fresh grass and clover.” “As a result, our […]

(Beyond Pesticides, June 4, 2008) On May 29, 2008, the U.S. Environmental Protection Agency (EPA) released its final risk mitigation decision for ten rodenticides, which outlines new measures it says will help protect children and the public from accidental poisonings as well as to decrease exposures to pets and wildlife from rodent-control products. However, because the decision omits key uses, allows continued applicator use of dangerous formulations, and recognizes a lack of product efficacy without a fully integrated program (yet does not require it on the label), environmentalists feel the final risk mitigation decision falls short of adequately protecting the health of people, wildlife and the environment.EPA is requiring that ten rodenticides used in bait products marketed to consumers be enclosed in bait stations, making the pesticide inaccessible to children and pets, and is also prohibiting the sale of loose bait, such as pellets, for use in homes. These ten rodenticides are: ”¢ Brodifacoum ”¢ Bromadiolone ”¢ Bromethalin ”¢ Chlorophacinone ”¢ Cholecalciferol ”¢ Difenacoum ”¢ Difethialone ”¢ Diphacinone ”¢ Warfarin ”¢ Zinc phosphide Exposure to children is also a major concern for these chemicals. According to the 2006 Annual Report of the American Association Poison Control Centers’ National Poison Data […]

(Beyond Pesticides, May 30, 2008) A recent study has linked the common herbicide atrazine with endocrine disruption in both fish and human cells. Entitled “The Herbicide Atrazine Activates Endocrine Gene Networks via Non-Steroidal NR5A Nuclear Receptors in Fish and Mammalian Cells,” the University of Califonia, San Francisco (UCSF) research examines the reaction of zebrafish to environmentally relevant levels of atrazine, and mirrors the study in human placental cells. The zebrafish, which are particularly sensitive to endocrine disruptors,  are “feminized”  in greater proportion than the unexposed control group. Fish exposed to atrazine for 48 hours at levels found in agricultural runoff produced twice as many female fish as male. “These fish are very sensitive to endocrine disrupting chemicals, so one might think of them as ‘sentinels’ to potential developmental dangers in humans,” said senior author Holly Ingraham, PhD. “These atrazine-sensitive genes are central to normal reproduction and are found in steroid producing tissues. You have to wonder about the long-term effects of exposing the rapidly developing fetus to atrazine or other endocrine disruptors.” In human cell studies, the researchers found that atrazine activates genes involved in hormone signally and steroid synthesis. “Endocrine-related cell types with a capacity for steroid generation appear […]

(Beyond Pesticides, April 3, 2008) Wines on sale in the European Union (EU), including wines made by world famous vineyards, contain residues of a number of pesticides, according to a new report by Pesticide Action Network Europe. The organization tested 40 bottles of wine purchased inside the EU from Australia, Austria, Chile, France, Italy, Germany, Portugal and South Africa, six of which were organic wines. Every bottle of conventional wine included in the analysis was found to contain pesticides, with one bottle containing 10 different pesticides. On average each wine sample contained over four pesticides. The analysis revealed 24 different pesticide contaminants, including five classified as being carcinogenic, mutagenic, toxic to the reproductive system or endocrine disrupting. The most widespread pesticide contaminant was pyrimethanil, a possible carcinogen, which was detected in 25 bottles of conventional wine — almost 75% of all conventional samples analyzed. While the majority of wines tested were selected from low cost affordable brands, three of the bottles are world famous Bordeaux wines and more expensive, according to PAN Europe. The discovery of pesticides in samples of wine follows the publication of a report by the French Ministry of Agriculture which identified 15 pesticides as being systematically […]

(Beyond Pesticides, March 20, 2008) A 2000-2005 U.S. Geological Survey (USGS) study, Pesticide Occurrence and Distribution in the Lower Clackamas River Basin, Oregon, 2000-2005, finds a variety of pesticides in river and tributary samples, along with trace-level detections of pesticides in treated drinking-water samples collected from a drinking-water treatment plant that uses the Clackamas River as a raw-water source. While the federal government is quick to point out that detections in drinking water are below existing Environmental Protection Agency (EPA) drinking-water standards and most river samples are below the agency’s aquatic life benchmarks, studies show hazardous endocrine-disrupting and immunosuppressive effects at extremely low levels — far below EPA standards. A total of 63 pesticide compounds were detected in 119 water samples collected during storm and non-storm conditions using low-level detection methods. More pesticides were detected in the tributaries than in the Clackamas River mainstem. One or more of 15 pesticides were detected in nine of 15 samples of drinking water. Environmental and public health advocates are concerned that these results add to a pattern of contamination across the country. USGS data released in 2008, shows widespread pesticide contamination in the Chesapeake Bay watershed, and a 2004 USGS report of nationwide […]

(Beyond Pesticides, March 4, 2008) Concern about environmental health and justice has exploded in our communities and around the world as a political and moral issue. One of the central threats, toxic pesticides, is directly linked to adverse health effects, particularly in children, and poisoning of the environment. We have learned enough in the last several decades since the publication of Silent Spring to make dramatic shifts away from toxic chemical dependency — as science increasingly links exposure to disease; insect, plant and bacteria resistance to chemicals multiplies; the energy and carbon footprint associated with pesticide use is documented; and the viability of sound and safe practices is realized. While the shift away from pesticide dependency has begun to take hold in communities around the world, conventional chemical intensive practices in agriculture and residential and institutional management continue to pose unjustifiable and unwarranted hazards. Regulatory standards and underlying laws accept unnecessary risks for workers that handle and work around pesticides and children who eat treated food, breathe contaminated air, or touch toxic surfaces. Studies link pesticides to cancer and immune, reproductive and nervous system damage. Subtle low level exposure effects that cause learning disabilities or impede brain function defy classical […]

(Beyond Pesticides, February 19, 2008) Common household chemicals and widespread pollutants are changing male reproductive health and impacting sexual function, development and cancer rates of today’s generations and possibly their offspring, according to more than 15 years of research by a Colorado State University expert. For example, one study looking at sperm counts globally from 1940, when chemicals first began to be widely produced, to the 1990s, indicates a 1.15 percent per year decline in sperm counts. These declines may be linked to chemical exposure.Rao Veeramachaneni, BVSc, MScVet, PhD, a biomedical sciences professor in the College of Veterinary Medicine and Biomedical Sciences, has found that chemicals including pesticides, common pollutants in ground water, and chemicals in plastics, make-up and nail polish are on a growing list of culprits causing developmental abnormalities such as impaired sperm quality and impotence. Reproductive health can be compromised if males are exposed at various times in life spanning from in utero up to adulthood.Dr. Veeramachaneni’s findings span the globe and are across species lines, from humans to horses, wildlife to frogs. His research, coupled with the collective findings of other experts in the field, indicates a strong link related to pollutants, and incidence of such […]

(Beyond Pesticides, January 22, 2008) Triclosan, a very common antibacterial chemical, is present in the plasma and breast milk of nursing mothers, according to a study by Swedish researchers. Every one of the 36 mothers tested positive for triclosan levels in their bodies, and the concentrations were clearly and significantly higher in the exposed group (i.e., those that use triclosan-containing products) than in the control group. This does not come as a surprise since triclosan is widely used in personal care products””including soaps, deodorants, and toothpaste””as well as plastics and textiles. Although there was high variability within groups, even members of the control group had triclosan present in their plasma, indicating that there are other significant sources of exposure outside of hygiene products. Triclosan is not removed from wastewater by conventional treatment processes and has been found in both wastewater effluent and sewage sludge. The authors of Triclosan in plasma and milk from Swedish nursing mothers and their exposure via personal care products say that the significance of the presence of triclosan in plasma and breast milk of nursing mothers is not easily deduced and that the health effects, especially the long-term effects of chronic exposure, of triclosan are not […]

(Beyond Pesticides, October 18, 2007) In a scholarly review written by Theo Colborn, Ph.D. and Lynn Carroll, Ph.D., the authors point to the multigenerational effects of some pesticides that they say demand improved regulation to protect human and environmental health. The review, “Pesticides, Sexual Development, Reproduction, and Fertility: Current Perspective and Future Direction,” appears in the international journal Human and Ecological Risk Assessment (13:5, 1078 — 1110), September, 2007. The study points out a major deficiency in the U.S. Environmental Protection Agency’s regulation of pesticides under current health reviews and risk assessments. The authors call EPA’s pesticide registration system “outmoded” and one that has “almost completely missed the low-dose and endocrine system-mediated effects of pesticides.” The study reviews both epidemiological and laboratory data. In the abstract, the authors state the following: Improvements in chemical analytical technology and non-invasive sampling protocols have made it easier to detect pesticides and their metabolites at very low concentrations in human tissues. Monitoring has revealed that pesticides penetrate both maternal and paternal reproductive tissues and organs, thus providing a pathway for initiating harm to their offspring starting before fertilization throughout gestation and lactation. This article explores the literature that addresses the parental pathway of exposure […]

(Beyond Pesticides, October 9, 2007) Two state agencies and the U.S. EPA are close to completing an investigation of the poisoning of over 100 farmworkers in Nevada two weeks ago. Chloropicrin, an agricultural fumigant, drifted to a worker-occupied field, sending 121 laborers to Saint Lyon Medical Center (SLMC) for treatment on the morning of September 26. Upon arrival, the workers were showing symptoms including difficulty breathing, nausea, watery eyes and sore throat. SLMC Administrator Joan Hall said that only 12 of the 121 people required emergency room care, and most returned to work the same afternoon. Normally, chloropicrin’s off-gas dissipates, but because of a weather inversion the fumigant stayed lower to the ground and drifted more than a half-mile away from its application area to the worker-occupied field. Speaking on behalf of local farming operation Peri & Sons Farms, media contact Tim Cummings said both the Nevada Department of Agriculture and Occupational Safety and Health Administration have concluded their portion of the report, with the remaining piece due from the EPA. Peri & Sons owns both fields, which are located just over a half-mile apart, far enough apart from each other for such applications, according to state regulations and the […]

(Beyond Pesticides, September 28, 2007) EPA is due to make a decision on methyl iodide, a highly reactive and carcinogenic chemical, for use in crop production as a soil fumigant. Scientists across the country are alarmed by the prospect of registering methyl iodide as a pesticide, and fifty-four chemists and physicians from across the country issued a letter to EPA Administrator Stephen Johnson Monday urging the Agency not to sanction the broad use of methyl iodide now or at any time.“[W]e are concerned that pregnant women and the fetus, children, the elderly, farm workers, and other people living near application sites would be at serious risk if methyl iodide is permitted for use in agriculture,” said the group in the letter. In the chemical community methyl iodide is a well-known cancer hazard due to its ability to mutate DNA, and the scientists are fearful that methyl iodide’s high volatility and water solubility will expose many people to harm if the chemical is used in agriculture. Methyl iodide and methyl bromide are injected into the soil at rates of 100-400 pounds per acre to kill soil-borne pests. Because of the high application rates and gaseous nature of these chemicals, they drift […]

(Beyond Pesticides, September 24, 2007) Seven representatives wrote to the EPA last Thursday, urging the government agency to act promptly to identify and screen products for dangerous endocrine-disrupting chemicals. The letter asks EPA Administrator Stephen Johnson to provide definite deadlines in the testing and control of endocrine disruptors, which are substances that interfere with the normal functioning of the endocrine system, responsible for hormonal and developmental processes. EPA’s regulation of these substances that mimic or alter natural hormonal processes has been slow and lacks direction to meet set goals promptly, according to the U.S. Representatives. “To date, EPA’s efforts in this area have been characterized by missed deadlines, prolonged delays, and inadequate incorporation of public input,” according to the letter from the House Committee on Oversight and Government Reform, chaired by Rep. Henry Waxman (D-California). Ranking Minority Member on the Committee Tom Davis (R-Virginia); Representatives Elijah Cummings (D-Maryland), Chris Van Hollen (D-Maryland), Wayne Gilchrest (R-Maryland), and Jim Moran (D-Virginia); and Delegate Eleanor Holmes Norton (D-D.C.) also signed the letter to EPA. Advocates say that EPA’s lack of urgency on endocrine disruptors leaves the American population and future generations at risk for adverse health effects from exposure to these substances through […]

(Beyond Pesticides, August 2, 2007) According to the Associated Press (AP), a new study finds frogs in Vermont living near farms are more than twice as likely as those living elsewhere to have deformities like missing legs. Yale University ecologist David Skelly, Ph.D., told the AP he decided to look at Vermont frogs because the state has been a hot spot during the last 10 years for deformed frogs. “We went to all these wetlands and cataloged where the deformities were found, and what kind of landscapes seemed to pose higher risks, if any,” Dr. Skelly said. “The answer was, frogs growing up in proximity to agriculture were more than two times as likely to have deformities. This doesn’t say it is chemical pesticides, but you can’t credibly consider this problem of the frogs without at least evaluating whether pesticides are involved.” Richard Levey, a biologist with the Vermont Agency of Natural Resources, said two common farm chemicals, atrazine and metolachlor, had been found in trace amounts in water from wetlands where deformed frogs had been found. But he told the AP that the concentrations were far below those thought to have any effect on aquatic life. Research by Tyrone […]

(Beyond Pesticides, July 23, 2007) New research finds several species of freshwater fish have lower temperature tolerances when exposed to the widely used pesticides endosulfan and chlorpyrifos. The discovery reveals another key pesticides issue in the global warming debate. The study, “The Effects of Three Organic Chemicals on the Upper Thermal Tolerances of Four Freshwater Fishes” (Environmental Toxicology and Chemistry, July 2007), is the work of Ronald Patra of Australia’s Department of Environment and Conservation and colleagues. The study establishes the upper temperature tolerances of both unexposed and exposed silver perch, eastern rainbowfish, western carp gudgeon and rainbow trout. Exposed fish were given sublethal doses of endosulfan, chlorpyrifos or phenol. The results show exposure to endosulfan cause a decrease of temperature tolerance in silver perch by 2.8 °C, eastern rainbowfish 4.1 °C, western carp gudgeon 3.1 °C, and rainbow trout 4.8 °C. Chlorpyrifos decreases temperature tolerance in silver perch by 3.8 °C, eastern rainbowfish 2.5 °C, western carp gudgeon 4.3 °C, and rainbow trout 5.9 °C. Phenol is not shown to cause a significant decrease in tolerance. The authors conclude, “The reduction in thermal tolerance of fish in the presence of endosulfan and chlorpyrifos suggest that, not only does temperature […]

(Beyond Pesticides, June 19, 2007) Scientists investigating a mysterious die-off of many of the nation’s honeybees are concentrating on pesticides and microorganisms as possible causes of the disorder, and some beekeepers are refusing to place their hives near chemically treated fields out of fear that pesticides may be contributing to the die-off. Scientists from Penn State University and the U.S. Department of Agriculture are leading the research into the disease, which has killed tens of thousands of bee colonies in at least 35 states. The die-off has threatened the livelihood of commercial beekeepers and strained fruit growers and other farmers who rely on bees to pollinate more than 90 flowering crops, including apples, nuts and citrus trees. After months of study, researchers cannot tie the ailment to any single factor. But scientists have zeroed in on a new, unnamed pathogen found in the dead bees, and on the role of pesticides, said Maryann Frazier, a senior extension associate in the university’s entomology department. David Hackenberg was the first beekeeper to report the disorder to Penn State last fall after losing nearly 75 percent of his 3,200 colonies. He has since rebuilt his business to 2,400 colonies, but now asks growers […]