(Beyond Pesticides, June 8, 2023) A study published in Nature Communications finds that climate-induced thawing of permafrost (a ground that remains completely frozen for two or more years) threatens approximately 4,500 industrial sites in regions of the Arctic. These thousands of industrial sites used to store hazardous substances have an estimated 13,000 to 20,000 contaminated locations. Not only do these regions pose a grave ecological risk to the Arctic, but they threaten the entire globe. Many studies warn that thawing permafrost in the Arctic region can prompt the reemergence of greenhouse gases (e.g., methane and carbon dioxide), microbes, and hazardous chemicals (e.g., banned pesticides like DDT, heavy metals, etc.). Gases, microbes, and chemicals can drift near the poles, becoming entrapped in ice under the accumulating snowfall. As the global climate continues to rise and the climate crisis worsens, studies like this heed warning of potential adverse effects as ice encapsulating these toxic chemicals melt. Upon melting, some chemicals can volatilize back into the atmosphere, releasing toxicants into the air and aquatic systems, with the ensuing consequences. Microbes frozen for thousands to millions of years can also emerge from thawing permafrost, with unknown implications on human, animal, and ecosystem health. The melting permafrost is already […]

(Beyond Pesticides, June 7, 2023) A systematic review of scientific literature published in Environmental Research on the development of mood disorders among pesticide applicators (farmers, landscapers, etc.) finds an increased risk of depression symptoms over the last decade. The evidence in the review highlights the presence of pesticide-specific biomarkers and biomarkers of depression that determine the positive association between pesticide exposure and the development of depressive symptoms. With more high-quality longitudinal studies to control sociocultural variables, researchers can directly pinpoint risks of developing depression, especially among agricultural workers and landscapers who use pesticides. Research on pesticide-induced diseases commonly investigates pesticide exposure concerning the development of various physical illnesses. However, previous studies show that occupational (work-related) risks of developing depression are high in agriculture, where pesticide use is rampant. Acute exposure to chemicals, including organophosphate, organochlorine, triazine, and carbamate pesticides, tends to put farmers at greater risk of suicide than the general population. There is a lack of information connecting pesticide exposure to the subsequent psychological (psychiatric) effects on the general population. Additionally, household pesticide exposure varies from occupational exposure via exposure frequency, duration, intensity, and type.   According to the World Health Organization (WHO), depression affects 322 million people globally, with the number of diagnosed patients increasing by 18.4% from 2005 to […]

Eco-Friendly Parks for All (EFPA)*, a coalition of environmental, public health and political action organizations, has teamed up with Beyond Pesticides, New York City Parks and Recreation Department, and Stonyfield Organic Yogurt to celebrate the success of pilot organic land management programs at eight sites across the five boroughs. 

(Beyond Pesticides, April 28, 2023) A study published in Science of The Total Environment finds agricultural communities encounter chronic and measurable pesticide exposure regardless of seasonal pesticide applications. Several biomonitoring studies demonstrate people living adjacent to or within agricultural areas often experience elevated levels of organophosphate (OP) insecticides, even while not working directly with OPs. Six dialkyl phosphate (DAP) metabolites (breakdown products) of OPs persist in urine during the spraying and non-spraying seasons. Despite 75 percent of OPs metabolizing into one or more of the six DAPs and excreting within six to 24 hours after exposure, the consistent levels of DAPs in urine highlight continuous exposure beyond regular seasonal pesticide applications. OP compounds have a global distribution, with evaporation and precipitation facilitating long-range atmospheric transport, deposition, and bioaccumulation of hazardous chemicals in the environment. OPs are highly toxic and, as this study shows, residues are consistently present in human and animal urine, as well as blood, tissues, and milk. Considering 90 percent of Americans have at least one pesticide compound in their body, primarily stemming from dietary exposure, including food and drinking water, advocates maintain that current restrictions on their use must adequately detect and assess total chemical contaminants. The study notes, “We suggest that among agricultural communities that experience […]

(Beyond Pesticides, April 27, 2023) The Nevada Assembly, by unanimous vote, took the state one step closer to banning the use of neonicotinoid insecticides used on plants, with a waiver for commercial agricultural purposes. Despite dramatic declines in bee populations linked to neonicotinoid pesticides and other toxic pesticides, the U.S. Environmental Protection (EPA) and state regulatory authorities have for the most part ignored beekeepers and the independent scientific literature by allowing widespread toxic pesticide use—forcing elected officials to take protective action. Portions of the bill would take effect upon passage or no later than January 1, 2024. Maine and New Jersey have adopted similar legislation. The failure to adequately regulate pesticides under federal law, the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), and EPA inaction is viewed by environmentalists as the shocking disregard for the importance of biodiversity to sustaining life. The inadequate restriction of pesticides and slower than necessary transition to organic land management practices are viewed as major contributors to the “insect apocalypse.” The legislation (A.B. 162), led by Assemblywoman Michelle Gorelow and a group of nine other Assemblymembers, illustrates a growing trend of local and state legislative bodies asserting their authority to protect against health, biodiversity, and […]

(Beyond Pesticides, April 14, 2023) In March, scientists at the National Marine Fisheries Service (NMFS) issued a draft Biological Opinion (BiOp) stating that carbaryl and methomyl — two commonly used carbamate insecticides — cause significant harm to dozens of already-endangered fish species in the Pacific Northwest’s Columbia, Willamette, and Snake rivers. The BiOp indicates that these toxic compounds, in wide use on orchards and field vegetables throughout the Willamette Valley, the Columbia River Gorge, and southeastern Washington, will likely threaten scores of species on the Endangered Species list: 37 species at risk from carbaryl and 30 from methomyl. In addition, the BiOp says, “both are likely to harm or destroy many areas designated as critical habitat for endangered species.” The mitigation measures proposed by NMFS and the U.S. Environmental Protection Agency (EPA), in light of this BiOp, are likely to be inadequate to the problem, given that both compounds can drift through air and/or migrate into groundwater and generate toxic runoff. These two neurotoxic insecticides, carbaryl and methomyl, are very toxic to bees, birds, fish, and other aquatic organisms. In addition, carbaryl is a likely human carcinogen and an endocrine disruptor, and has harmful impacts on multiple bodily systems. Methomyl is […]

(Beyond Pesticides, April 12, 2023) Spring represents a period of increased water, soil, and general ecosystem pollution, correlated with increased pesticide use and increased rainfall. Thus, April showers bring May flowers, and often pesticides. We offer this overview to share with friends, family, and your community in an effort to elevate the urgent need to eliminate pesticides and make the shift to organic land management. Pesticides are pervasive in the environment, affecting all ecosystems, including air, water, and soil. Like clean air and water, healthy soils are integral to ecosystem function, interacting between Earth’s four main spheres (i.e., hydrosphere, biosphere, lithosphere, and atmosphere) to support life. Pesticide use results in pervasive contamination of treated and nontarget sites. Even organic farmers and gardeners globally suffer from the widespread movement of pesticides through the air, water, and runoff from land. Attempts to protect property and ecosystems from pesticide use are a difficult, some say impossible, challenge. Efforts to prevent contamination become a large burden, with attempts to curtail pesticide drift with buffer zone areas and eliminate fertilizers or soil supplements with pesticide residues (e.g., manure and compost). Furthermore, the effects of climate change only exacerbate threats to ecosystem health, as studies show a […]

(Beyond Pesticides, April 6, 2023) A study published in Global Change Biology adds to research demonstrating that climate change can exacerbate the adverse impacts of pesticide exposure on managed and wild bees. Temperature can alter the sublethal effect pesticides, particularly the neonicotinoid (neonic) imidacloprid and the sulfoximine sulfoxaflor, have on bumble bee behavior tied to fitness and pollination services. Both an increase and decrease in temperature can cause diverging thermal responses in bumble bee behavior. However, increasing temperature bares more severe behavior abnormalities than cooler temperatures. The pervasiveness of pesticide exposure combined with climate change threatens global species biodiversity. As has been widely reported, pollinators (such as bees, monarch butterflies, and bats) are a bellwether for environmental stress as individuals and as colonies. Pesticides intensify pollinators’ vulnerability to health risks (such as pathogens and parasites), with pesticide-contaminated conditions limiting colony productivity, growth, and survival. Now more than ever, people are changing their sentiment toward sustainability, with two-thirds of consumers stating the importance of limiting climate change impacts and 88 percent supporting greater pollution reduction. The globe is currently going through the Holocene Extinction, Earth’s 6th mass extinction, with one million species of plants and animals at risk. With the increasing rate of biodiversity loss, advocates say it is essential for […]

(Beyond Pesticides, March 30, 2023) A study published in Ecotoxicology and Environmental Safety finds that the commonly used herbicide, atrazine, promotes breast cancer development through suppression of immune cell stimulation, and thus function, and upregulation of enzymes mediating tumor development. According to the Centers for Disease Control and Prevention (CDC), breast cancer is a disease that causes breast cells to grow out of control, with the type of breast cancer depending on the cells themselves. Several studies and reports, including U.S. Environmental Protection Agency (EPA) data, identify hundreds of chemicals as influential factors associated with breast cancer risk. Breast cancer is the most common cancer among women, causing the second most cancer-related deaths in the United States. Past studies suggest genetic inheritance factors influence breast cancer occurrence. However, genetic factors only play a minor role in the incidence of breast cancer, while exposure to external environmental factors (i.e., chemical exposure) appears to play a more notable role. One in ten women will receive a breast cancer diagnosis, and genetics can only account for five to ten percent of cases. There are grave concerns over exposure to endocrine (hormone) disrupting chemicals and pollutants that cause adverse health effects. Therefore, advocates point to the need for national […]

(Beyond Pesticides, March 10, 2023) Following years of discussions and negotiations, 193 United Nations member countries have just approved — for the first time — a draft treaty for protection of the globe’s “high seas” and their denizens. The March 4 adoption of the draft marks the achievement of a potential legal framework for such protections, but is also the beginning of “a long journey to ensure the world’s oceans are adequately protected for future generations,” according to coverage by NewScientist. As research out of Boston College identifies, our oceans are badly polluted by multiple substances — including pesticides and other agricultural runoff; industrial and petrochemical waste; and the synthetic chemicals embedded in plastics — that threaten human health. The treaty, which must be adopted by member states and then ratified by at least 60 countries to take effect could be a critical development for meeting the COP15 “30 by 30” goal of protecting 30% of the world’s land and sea by 2030 to slow and arrest global biodiversity losses. Beyond Pesticides has long covered the ecological harms of ocean pollution.  The treaty represents a step toward implementation of President Biden’s 2021 “America the Beautiful Initiative,” proclaiming “the first-ever national conservation goal” established […]

(Beyond Pesticides, March 6, 2023) After the Trump EPA was blocked from weakening the application exclusion zone (AEZ) provisions for protecting farmworkers, the rules reverted to the Obama era rules. Now, EPA proposes to reaffirm part of that rule, while accepting some of the weakening amendments from the Trump administration. Tell EPA to strengthen pesticide rules to protect farmworkers. Tell President Biden to sign the International Convention on the Protection of the Rights of All Migrant Workers and Members of Their Families.    EPA’s Worker Protection Standards (WPS) are rules that govern labor safety standards within federal pesticide law (the Federal Insecticide Fungicide and Rodenticide Act, or FIFRA). Farmworkers are not covered for toxic chemical exposure by the U.S. Department of Labor’s Occupational Safety and Health Administration (OSHA), and WPS have long been criticized by farmworker, labor, and health advocates for providing insufficient protections for farmworkers, their children and communities. Under the WPS, AEZs are buffer zones where people are not allowed to enter during the course of a pesticide application. Like all buffer zones, they are designed to allow application of toxic pesticides while providing a nominal degree of protection. Pesticides drift long distances when being applied and they […]

(Beyond Pesticides, March 2, 2023) On February 22, a group of 65 nonprofit organizations (including Beyond Pesticides) filed a citizen petition with the U.S. Environmental Protection Agency (EPA) that asks the agency to close a gaping — and well exploited — regulatory loophole by revoking a 1984 regulation that waived efficacy data requirements in pesticide evaluations. This means that EPA has, for 39 years, registered pesticides without demonstrated proof of efficacy and benefits. The petition is aimed primarily at the widespread use of neonicotinoid insecticides (neonics), which are so harmful to hundreds of species — and to bees, other pollinators, and birds, in particular — that many advocates have insisted they should be banned altogether. Beyond Pesticides has advocated for a neonics ban because of their extensive harms to pollinators, multiple other organisms (including humans), ecosystems, and natural resources. The Center for Food Safety, Pesticide Action Network North America, Center for Biological Diversity, Beyond Pesticides, and other advocates have filed lawsuits in recent years to get EPA to act protectively on neonics and other pesticides. The coalition of groups in the subject case seeks to rein in a plethora of harmful impacts of neonics, given EPA’s overall lack of protective action. (For […]

(Beyond Pesticides, February 27, 2023) California’s Department of Pesticide Regulation (DPR) is asking for comments on its “Sustainable Pest Management (SPM) Roadmap” by 5 pm (PST) March 13, 2023. While recognizing problems inherent in traditional integrated pest management (IPM), DPR’s roadmap is directing us to a destination that includes another generation of exposure to the worst of the worst pesticides—while failing to embrace the elimination of farm inputs harmful to ecosystems and the capacity of soil biology to cycle nutrients and draw down the maximum amount of atmospheric carbon. The Roadmap’s off-handed rejection of organic practices, rather than building on organic systems, creates a lost opportunity for adopting a holistic and serious solution to the current crises of health threats from pesticides, biodiversity collapse, and the climate emergency. Tell DPR to revise its destination to immediately eliminate the worst pesticides and implement wide scale transition to organic practices. DPR’s Roadmap states these goals: By 2050, eliminate the use of Priority Pesticides by transitioning to SPM. By 2050, SPM will be adopted as the de facto pest management system in California. DPR says “The criteria for classifying pesticides as “Priority Pesticides” include, but are not limited to, hazard and risk classifications, […]

(Beyond Pesticides, February 21, 2023) The recent train derailment in East Palestine, Ohio, should be a reminder to all of us that problems with our reliance on toxic chemicals go beyond broadcasting them on fields. In order to get pesticides to their point of use, toxic precursors and ingredients must be transported. Toxic waste products are also delivered to a location where they may be burned or deposited in a landfill. In weighing the hazards of toxic pesticides, these ancillary hazards should also be considered. Tell EPA and Congress that all impacts of toxic chemicals—from cradle to grave—must be considered before allowing their use.      The freight train that derailed February 3, 2023 in East Palestine was carrying a number of toxic chemicals. EPA notified the railroad, “EPA has spent, or is considering spending, public funds to investigate and control releases of hazardous substances or potential releases of hazardous substances at the Site. Based on information presently available to EPA, EPA has determined that Norfolk Southern Railway Company (Norfolk Southern or “you”) may be responsible under CERCLA [Comprehensive Environmental Response, Compensation, and Liability Act–Superfund] for cleanup of the Site or costs EPA has incurred in cleaning up the Site.” But […]

(Beyond Pesticides, February 17, 2023) The February 3 derailment of a Norfolk Southern train in Ohio has been huge news. Less well known perhaps is that 20 of the 50 cars involved were carrying hazardous materials, defined by the National Transportation Safety Board as “cargo that could pose any kind of danger ‘including flammables, combustibles, or environmental risks.’” The incident resulted in a huge fire, evacuations, and worries about explosions and discharge of toxic chemical gases; on February 6, officials conducted “controlled releases” of some of the chemicals. Some of the toxic chemicals involved are precursors to production of synthetic pesticides. [Eds. Note: We are deeply concerned for the victims of this terrible crisis who are asking legitimate questions about contaminated drinking water and the effects of both the initial acute exposure after the derailment, resulting in the release of toxic chemicals, and long-term exposure to low levels of toxic residues in homes and the environment.] Among the compounds on board those 20 cars were “inert” pesticide ingredients (vinyl chloride, ethylhexyl acrylate, and isobutylene), an antimicrobial compound (ethylene glycol monobutyl ether [EGBE]), benzene (a carcinogenic solvent), and butyl acrylate. This event brings into high relief the cradle-to-grave issues that travel […]

(Beyond Pesticides, February 7, 2023) U.S. Senator Cory Booker (D-N.J.) reintroduced legislation last week to increase protections against exposure to toxic pesticides. The Protect America’s Children from Toxic Pesticides Act of 2023 (PACTPA), S.269, addresses many of the controversial issues with the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), which governs the registration and use of pesticides in the U.S. This major reform legislation tackles some of the documented deficiencies in the regulation of pesticides and removes a number of loopholes in the law. The legislation, introduced with Senators Kirsten Gillibrand (D-NY), Bernie Sanders (D-VT), Elizabeth Warren (D-MA) and Brian Schatz (D-HI), also includes a ban on all organophosphate and neonicotinoid insecticides, as well as  the weed killer paraquat, which is known to cause Parkinson’s disease and lung fibrosis. Despite these reform provisions, the legislation does not touch the core of FIFRA’s pesticide registration process and chart a path for the systemic, transformative change that Beyond Pesticides says is essential to meet the existential challenges of current times—devastating health threats, biodiversity collapse, and the climate crisis. FIFRA, which is under the jurisdiction of the agriculture committees of Congress, has long been criticized for failing to protect the public and workers […]

(Beyond Pesticides, February 6, 2023) During Black History Month, it is of note that on January 10, the Biden-Harris Environmental Protection Agency (EPA) announced funding of approximately $100 million for “projects that advance environmental justice in underserved and overburdened communities across the country” through its Environmental Justice Government-to-Government (EJG2G) program. While viewed as assistance for those communities “disproportionately impacted by pollution and climate change,” it is important to recognize that the same communities are also disproportionately impacted by activities that produce pollution and climate change. Tell EPA, Governors (Mayor in DC), and Congress to support environmental justice by eliminating activities leading to pollution and climate change. EPA must reverse its historical bias against preventive action to ensure the protection of those disproportionately poisoned by toxic chemicals. While critically important to clean up contaminated communities, EPA must stop the flow of toxic pesticides at the front end because of the disproportionate poisoning effects of use, handling, transportation, and disposal. We live in an age of practices and products that make toxic pesticides unnecessary and their use unconscionable. Yet, EPA insists on the acceptability of harm (which it calls risk), despite its failure to (i) recognize comorbidities and preexisting health conditions, (ii) […]

(Beyond Pesticides, February 1, 2023) Honey bee declines in the United States are “primarily related” to pesticide exposure, parasitic mites, and extreme weather conditions, research published by Penn State scientists have determined. Publishing the results in Scientific Reports, the researchers aim to provide a national overview of the range of factors harming bee colonies. “Some previous studies have explored several potential stressors related to colony loss in a detailed way but are limited to narrow, regional areas,” said study co-author Luca Insolia, PhD. “The one study that we know of at the national level in the United States explored only a single potential stressor. For this study, we integrated many large datasets at different spatial and temporal resolutions and used new, sophisticated statistical methods to assess several potential stressors associated with colony collapse across the U.S.” The results reinforce calls from bee health advocates in the U.S. and around the world: eliminate toxic pesticide use, the lowest hanging fruit contributing to pollinator declines. In order to create a more comprehensive national overview, geographers, entomologists, and statisticians all participated in the study, reviewing publicly available data on colony health, land use, weather, and other environmental factors over a five-year period from […]

(Beyond Pesticides, January 26, 2023) A study published in Food Safety and Toxicology finds that the widely used fungicide azoxystrobin (AZO), used in food production and turf management, can disrupt the function of the intestinal (colonic) barrier responsible for the absorption of nutrients and defense against harmful substances. This and other similar data are important because the U.S. Environmental Protection Agency (EPA), with its required pesticide testing protocol, says that the chemical has “low acute and chronic toxicity to humans, birds, mammals, and bees,” and speaks to the need for the agency to modernize its registration requirements. [The agency does note that AZO is “is highly toxic to freshwater fish, freshwater invertebrates, and estuarine/marine fish, and very highly toxic to estuarine/marine invertebrates.] AZO is a broad-spectrum chemical used in wheat, barley, oats, rye, soya, cotton, rice, strawberry, peas, beans, onions, and a long list of other vegetables, as well as on lawns and golf courses, on a range of fungal diseases. The intestinal (colonic) barrier prevents the internal environment from damage caused by exogenous toxins to ensure internal homeostasis, impeding incidences of systemic inflammatory response syndrome (SIRS), sepsis, and multiple organ dysfunction syndrome (MODS). The intestines host a group of microorganisms that form […]

(Beyond Pesticides, January 24, 2023) Oral arguments begin this week in a lawsuit challenging the U.S. Environmental Protection Agency’s (EPA) approval of the antibiotic streptomycin as a pesticide on citrus crops. Brought forth by a coalition of farmworker, health, and environmental groups, the lawsuit aims to stop the use of a critical medical treatment for agricultural purposes. “Humanity’s dwindling supply of medically effective antibiotics is not worth sacrificing for an industry that has safer alternatives available,” said Drew Toher, community resource and policy director at Beyond Pesticides. “Despite the challenges, we know from the elimination of this material in organic production that we don’t need antibiotics in order to produce a glass of orange juice.”  In 2020, the Lancet published an article that identifies several of the multiple and interacting crises the U.S. and world face, with a focus on another “looming potential pandemic . . . [a] rise in multidrug-resistant bacterial infections that are undetected, undiagnosed, and increasingly untreatable, [whose rise] threatens the health of people in the USA and globally.” It calls on leaders in the U.S. and beyond, asking that even as they address the current coronavirus pandemic, they also attend to the antimicrobial resistance (AMR) problem, […]

(Beyond Pesticides, January 19, 2023) Research published in Environmental Health Perspectives finds the presence of nine various neonicotinoids (neonics) and six neonic metabolites within human cerebrospinal fluid (CSF). CSF is an essential part of the central nervous system (CNS), especially for CNS development. Specific chemical biomarkers (measurable indicators of biological state), like pesticides, found in CSF are useful for diagnosing and evaluating numerous neurological diseases. The nervous system is an integral part of the human body and includes the brain, spinal cord, a vast network of nerves and neurons, all of which are responsible for many of our bodily functions—from sensed to movement. However, mounting evidence over the past years shows that chronic exposure to sublethal (low) levels of pesticides can cause neurotoxic effects or exacerbate preexisting chemical damage to the nervous system. The impacts of pesticides on the nervous system, including the brain, are hazardous, especially for chronically exposed individuals (e.g., farmworkers) or during critical windows of vulnerability and development (e.g., childhood, pregnancy). Researchers identify the role agricultural chemicals play in CNS impacts causing neurological diseases, like amyotrophic lateral sclerosis (ALS) and Parkinson’s disease, dementia-like diseases such as Alzheimer’s, and other effects on cognitive function. Over 300 environmental contaminants and their byproducts, including pesticides, are chemicals commonly present in human blood […]

(Beyond Pesticides, January 16, 2023) Martin Luther King, Jr. spoke about individual greatness on February 4, 1968 to his congregation at Ebenezer Baptist Church in Atlanta two months before he was assassinated. We take this day—Monday, January 16— to commemorate the life and work of Martin Luther King, Jr. as an inspiration for taking on the challenges of justice, equity, and safety as a central part of all our work for a sustainable future. It will take the recognition of the greatness that all individuals have within to raise our voices in our communities to stop the toxic petrochemical assault and advance viable solutions that effect a transformation to organic practices and products. In so doing, we will address those who suffer the most harm from petrochemicals—in their production, transportation, use, and disposal. Whether determining our community’s management of public lands, playing fields, and parks, or choosing food grown without toxic chemicals, or creating habitat for biodiversity, we as individuals and collectively are the instruments for effecting meaningful change. This is true whether focused on an individual chemical exposure or in taking on the existential health, biodiversity, and climate crises of our day. Dr. King’s complete quote from which the […]

(Beyond Pesticides, January 12, 2023) Exposure to certain pesticides among individuals diagnosed with Parkinson’s disease (PD) can increase the risk of symptom progression. According to a study published in Science of the Total Environment, nearly 20 percent of pesticides associated with the onset of PD also increase the risk of faster decline in motor and non-motor function. Several studies find exposure to chemical toxicants, like pesticides, has neurotoxic effects or exacerbates preexisting chemical damage to the nervous system. Past studies suggest neurological damage from oxidative stress, cell dysfunction, and synapse impairment, among others, can increase the incidence of PD following pesticide exposure. Despite the association between PD onset via pesticide exposure patterns, few epidemiologic studies examine the influence pesticides have on worsening motor and non-motor symptoms in PD. Parkinson’s disease is the second most common neurodegenerative disease, with at least one million Americans living with PD and about 50,000 new diagnoses annually. The disease affects 50 percent more men than women, and individuals with PD have a variety of symptoms, including loss of muscle control and trembling, anxiety and depression, constipation and urinary difficulties, dementia, and sleep disturbances. Over time, symptoms intensify, but there is no current cure for this fatal disease. While […]