(Beyond Pesticides, October 3, 2024) The American Academy of Pediatrics published a technical report in September on antimicrobial resistance, which it calls a global public health threat, identifying the health implications of antibiotic use in animal agriculture. The lead authors, both medical doctors from the Department of Pediatrics at Vanderbilt University Medical Center, note the rise in antimicrobial-resistant infections that result in increased morbidity, mortality, and health care costs for not only adults, but infants and children as well. “[A]ll use of antimicrobial agents exerts selective pressure that increases the risk of development of resistance,” the authors state, highlighting the importance of limiting antimicrobial uses. “Antimicrobial resistance is an organism’s ability to survive exposure to an antimicrobial agent that was previously an effective treatment. Resistance traits can be acquired either through new mutations or through transfer of genetic material between organisms,” the authors report. Antimicrobial-resistant pathogens, such as bacteria and viruses, can be transmitted “through the food supply, direct contact with animals, environmental pathways, and contact with infected or colonized humans,” they continue. Use of antimicrobial agents, especially over extended periods of time or with repeated exposure, can cause resistance to not only that agent, but to multiple agents. As […]

(Beyond Pesticides, October 2, 2024) A comprehensive literature review in Ecotoxicology and Environmental Safety links a heightened risk of spontaneous abortion (SAB) with pesticide exposure. “The strengths of our study include being the first systematic review and meta-analysis to explore the association between exposure to pesticides and the risk of SAB,” the authors say. This novel approach includes analyzing 18 studies, totaling 439,097 pregnant participants, that allows the researchers to highlight an important public health issue and raise concerns for maternal contact with the harmful chemicals in pesticide products. SAB, also known as spontaneous miscarriage, is defined as the loss of pregnancy occurring prior to 20 weeks of gestation. “It has been observed that approximately 10–15% of pregnancies end up terminating spontaneously,” the researchers report. According to the authors, these negative birth outcomes can be attributed to many factors such as advanced maternal age, anatomical, immunological, and endocrinological disorders, infections, tobacco use, alcohol intake, abnormalities of the placenta, and exposure to heavy metals, radiation, and pesticides. To connect SAB specifically to pesticide exposure in mothers, a literature search was conducted for peer-reviewed studies that include pregnant study participants, ages 16 and above, who report “exposure to one or more pesticides […]

(Beyond Pesticides, September 30, 2024) Public Comment Period on Issues of Organic Integrity Closes Today. Farming is a notoriously risky enterprise, and organic farming presents further challenges along with its multiple benefits. Generally, organic has made great strides over the last several years and is strongly supported by American consumers, findings in the latest U.S. Department of Agriculture (USDA) Census. Even late this year, there is the prospect of several more important changes that will improve the organic certification process and some issues that will take more policy changes to resolve in the future. As a part of this process to ensure the integrity of the USDA organic label and the permitted production practices, Beyond Pesticides urges that the public submit comments TODAY (the last day for the comment period) on issues currently before the National Organic Standards Board (NOSB). See two sets of comments on key issues that can be submitted with one click each. Click here on issues related to use of plastic, nonorganic ingredients in processed food, and seeds and plant starts. Click here on inert ingredients, contaminants in compost, and drugs in livestock production. U.S. agriculture overall has remained fairly robust between the USDA Census in […]

(Beyond Pesticides, September 26, 2024) DNA damage is significantly higher in Latinx children from rural, farmworker families than children in urban, non-farmworker families, according to a recent study published by French and American authors in the journal Exposure and Health. Not only do farmworker children test positive for organophosphate pesticides more frequently than non-farmworker children, but the study finds that farmworker children also experience an increased frequency of DNA damage associated with the presence of organophosphate exposure. These results highlight the disparities in exposures and outcomes for children from vulnerable immigrant communities. Advocates note that as long as pesticides remain in use, farmworkers and their families will continue to shoulder a disproportionate share of the toxic effects of these chemicals (see here, here, and here); another in a long line of reasons to shift away from toxic synthetic pesticide use to the adoption of proven organic, regenerative agricultural practices. (See here, here, and here). Methodology The study assesses pesticide exposure and DNA damage in 45 Latinx children ages 10 to 12 from rural, farmworker families (30) and urban, non-farmworker families (15). Participants were selected from a larger study, Preventing Agricultural Chemical Exposure (PACE5)—a community-based research project by the North Carolina […]

(Beyond Pesticides, September 25, 2024) In a semiannual report released in August 2024, EPA’s Office of Inspector General (OIG) identifies a number of “unresolved” issues that strike the core of the agency’s failure to carry out its responsibilities to protect health and the environment. One of the issues identified is EPA’s failure to conduct an adequate and independent assessment of the cancer effects of the fumigant, 1,3-Dichloropropene (1,3-D or Telone). OIG’s original report, The EPA Needs to Improve the Transparency of Its Cancer-Assessment Process for Pesticides, was issued in 2022 and concluded that EPA’s Office of Pesticide Programs (OPP) engages in secret meetings with industry, elevates unqualified individuals to decision-making roles, uses an untested scientific approach, fails to conduct a simple literature review, and neglects public transparency. Other pesticide issues that OIG identified in its report include: The EPA Needs to Determine Whether Seresto Pet Collars Pose an Unreasonable Risk to Pet Health The EPA Has Not Verified that Its Laboratories Comply with Hazardous Waste Requirements EPA Needs an Agencywide Strategic Action Plan to Address Harmful Algal Blooms EPA’s Endocrine Disruptor Screening Program Has Made Limited Progress in Assessing Pesticides EPA Needs to Evaluate the Impact of the Revised Agricultural Worker […]

(Beyond Pesticides, September 24, 2024) Recent commentary in Frontiers in Toxicology by two researchers, Maricel Maffini, PhD and Laura Vandenberg, PhD, highlights the pitfalls in the current regulatory systems in the United States (U.S.) for chemicals that threaten human health. Despite many advancements in science over the past few decades, and the wealth of studies that tie chemical exposure to negative health effects, risk assessments, and subsequent risk management, remain “static” and “outdated,” according to the authors. “There is increasing concern amongst public health professionals, environmental health scientists, and medical organizations about exposures to synthetic chemicals,” the researchers say. “These organizations’ concerns are based on the overwhelming evidence showing associations between chemical exposures and adverse health outcomes in human populations.” Such concerns have sparked a debate on current regulatory methods for chemicals that are present in highly used products, such as pesticides, plastic containers, and food.    The authors continue, “There are now thousands of studies showing associations between these chemicals and adverse health effects in humans including neurological disorders and learning disabilities, metabolic outcomes, infertility, thyroid dysfunction, and cancers.” Additional health effects can be seen in the Pesticide-Induced Diseases Database. Of the many harmful chemicals, per- and polyfluoroalkyl substances […]

(Beyond Pesticides, September 20, 2024) As the California State Assembly wrapped up the 2024 legislative session, what was once a proposed ban of the deadly weed killer paraquat (in both agricultural and nonagricultural contexts) was amended and passed as a requirement for California Department of Pesticide Regulation to complete an “expedited review” by January 1, 2029. Paraquat exposure has been linked to Parkinson’s disease. According to reporting by Los Angeles Times, Assemblymember Laura Friedman (D-Burbank) (the original sponsor of the bill) spoke candidly about the prospects for this legislation, “We never thought we’d get a full ban through the Legislature. But we had to push as hard as we could.” Assemblymember Friedman is chair of the bicameral Environmental Caucus and a self-described “steadfast advocate for the environment [and] sustainable communities.” Environmental advocates, public health professionals, and many who have been affected by Parkinson’s disease are calling for the emergency suspension of paraquat, applying the same standard used by the U.S. Environmental Protection Agency (EPA) to ban the herbicide Dacthal/DCPA last month. (See Daily News here.) Context The original legislation responds to significant scientific documentation of the pesticide’s hazards, and an unresponsive regulatory process, as well as previous legislation efforts. In […]

(Beyond Pesticides, September 19, 2024) An article published in the journal Science of the Total Environment finds that the European Union’s (EU) risk assessment process, required for registration, fails to accurately or reliably predict pesticide exposure rates, sometimes by several orders of magnitude. Pesticide registration in the EU leverages the Agricultural Operator Exposure Model (AOEM)—a predictive model developed in 2014 to estimate expected non-dietary pesticide exposure levels for operators [pest control operators in the U.S.] based on a very limited set of data generated by the pesticide industry. Models that predict real-world exposure and underestimate field data raise critical questions about the efficacy of risk assessment reviews that determine product labels and allowed level of harm. By comparing the dermal exposure measured during a field study conducted in a nonagricultural area with the corresponding values estimated by AOEM, researchers in France add to the body of scientific literature indicating that the fossil fuel and petrochemical pesticide industry data cannot be relied upon as a benchmark to ensure public health and safety. The study describes the difficulty and complexity of calculating the ability of protective equipment to provide protection. According to the authors, “[AOEM] underestimated hand exposure by 42 times and […]

(Beyond Pesticides, September 18, 2024) A literature review in Trends in Analytical Chemistry analyzes scientific articles from the last ten years from around the globe that identify more than 300 pesticides in bee pollen. Bee pollen, often used as an edible dietary supplement, is not regulated for pesticide residues, which sparks concern for human exposure due to contamination with pesticides, heavy metals, metalloids, and mycotoxins. “Bee pollen is a food supplement that is receiving increasing attention for its nutraceutical and therapeutic properties. However, several uncertainties on the safety of this beekeeping product still exist. The present work addressed this issue through the critical evaluation of 61 studies, published over the 2014–2024 period,” the Spanish authors state. Bee pollen is produced by honey bees. After they forage on flowers and gather pollen on their hind legs (in pollen baskets or corbiculae) to transport back to the hive, it is moistened with nectar and salivary secretions to create bee pollen in the form of pellets. While the composition of bee pollen can vary between geographical locations with different flowers, the studies reviewed all utilize mass spectrometry to pinpoint pesticides, as well as mycotoxins (created by naturally occurring mold spores), that threaten human […]

(Beyond Pesticides, September 17, 2024) Today, International Microorganism Day, is a prime moment to focus on the complexity of billions of living beings that establish the foundation of land management and food production. Organic advocates, community members, and farmers identify the protection and enhancement of biological diversity in the soil as a key goal, especially in light of mounting concerns over rising microbial resistance to chemical-intensive practices. A recent article in British Journal of Environmental Sciences points to several microbial populations adversely affected by pesticide-contaminated soil on various farmland plots in Nigeria. There are significant variations in bacteria presence between pesticide-treated and control plots, with a lab analysis finding “[s]eventy-five percent (75%) of pesticide residue was detected in the soil samples,” which includes paraquat dichloride, endosulfan, diazinon, and N-(phosponomethyl)glycine [glyphosate]. This report builds on years of research from higher education institutions worldwide, including participatory research centering applied experiments on farmland, demonstrating the consequences of relying on pesticide-intensive agriculture and land management. The main goal of this report is to “determine the influence of pesticide contamination on the microbial population, physiochemical parameters and pesticide residue of soil of selected farmlands in Otuoke, Bayelsa State, Nigeria.” Researchers document the presence of eleven […]

(Beyond Pesticides, September 16, 2024) After the release of a hard-hitting study last week published in Science that pinpoints the cycle of increasing pesticide use with ecosystem and bat decline, resulting in higher infant mortality, Beyond Pesticides is calling for state and local action to transition public land to organic practices. Without a healthy ecosystem, the study documents increased pesticide use with dramatic adverse health effects. To take corrective action, Beyond Pesticides’ action asks governors and mayors to do the following: Eliminate the use of pesticides that imperil bats by adopting biodiversity conservation goals including— (1) ecological mosquito management with measures that recognize the benefit of preventive strategies, establish source reduction programs to manage breeding sites on public lands, educate on the management of private lands, employ programs for larval management with biological controls, and eliminate the use of toxic pesticides; (2) prohibition of systemic insecticides and treated seeds, including neonicotinoids; and (3) land management on public lands—including hospitals, higher education institutions, schools, and parks—using regenerative organic principles and organic certified practices and products, to transition to a viable organic system that prioritizes long-term health of the public, ecology, and economy. The new research connects declines in bat populations with increased […]

(Beyond Pesticides, September 13, 2024) While chemical companies persist in pushing simplistic solutions to complex problems, there is a large amount of evidence that organic farming presents effective solutions to many of those problems. Now there is new evidence that organic agriculture prevents the untold harms of pesticide-driven monoculture. In a new study, German researchers compared 16 agricultural landscapes in Lower Saxony and northern Hesse that had different combinations of semi-natural habitat, organic practices, and annual and perennial flower strips. Overall, the researchers find that organic farming provides the highest benefit to the bees, along with the presence of diverse flowering plants in and near monoculture fields. The study compares the effects of three honey bee conservation methods on the prevalence of the parasitic mite Varroa destructor and the 11 parasites Varroa transfers to bees, and the impact of these destructive organisms on bee colony growth. The findings were reported in the June issue of the Journal of Applied Ecology. Organic practices lead directly to lower parasite load and higher colony growth—essentially, the more organic crops, the more bees, and the more parasites, the fewer bees. Pesticides plus monoculture doubles the damage: Pesticides increase mortality, damage bees’ immune systems, and […]

(Beyond Pesticides, September 11, 2024) A literature review in Environments, written by researchers from South Korea and Ghana, highlights the threat to nontarget species and the biodiversity of insects that occur as a result of agricultural pesticide use. “Insects have experienced a greater species abundance decline than birds, plants, and other organisms, which could pose a significant challenge to global ecosystem management. Although other factors such as urbanisation, deforestation, monoculture, and industrialisation may have contributed to the decline in insect species, the extensive application of agro-chemicals appears to cause the most serious threat,” the authors state. The so-called “insect apocalypse” has been reported with one-quarter of the global insect population lost since 1990.  The authors, seeking to summarize the decline in insect species richness and abundance, link reliance on petrochemical pesticides and synthetic fertilizers to cascading negative impacts. Insects provide many important services, such as maintaining healthy soil, recycling nutrients, pollinating flowers and crops, and controlling pests. These nontarget and beneficial species are at risk through pesticide exposure, both directly and indirectly, which then affects these essential functions.   “Extensive and indiscriminate pesticide application on a commercial scale affects insect species abundance and non-target organisms by interfering with their growth, […]

(Beyond Pesticides, September 10, 2024) Results from a natural experiment, published in Science, shows ecosystem disruption of bat populations with cascading impacts on human health. Eyal Frank, PhD, an assistant professor of the Harris School of Public Policy at the University of Chicago, links increased insecticide use in croplands in the absence of bat species to a rise in infant mortality. As Dr. Frank says in an article in Science Daily, “[B]ats do add value to society in their role as natural pesticides, and this study shows that their decline can be harmful to humans.”  Many farmers rely on bats as alternatives to pesticides to protect their crops from insects, but White-Nose Syndrome (WNS) has greatly impacted bat populations since 2006. With the collapse of many bat populations in counties in North America, these farmers turn to toxic chemicals to replace the ecosystem services bats usually provide. These chemicals, however, lead to ripples through the ecosystem and endanger human health.  WNS is an invasive fungus (Pseudogymnoascus destructans) found in caves that affects bats during hibernation. As highlighted in an article in the New York Times, three species of bats in North America have been decimated by this syndrome, and bats […]

(Beyond Pesticides, September 9, 2024)  Comments are due by 11:59 PM EDT on September 30, 2024. With the opening of the public comment period on organic standards that determine the integrity, strength, and growth of the organic agricultural sector, a study was released last week that shows degradation of the ecosystem linked to increased infant mortality associated with higher pesticide use by chemical-intensive farmers compensating for losses in bat populations. It is well known that bats, among other wildlife including birds and bees, provide important ecosystem services to farmers by helping to manage pest populations and increase plant resilience and productivity. While degradation of ecosystems is attributable to many factors, pesticide use accounts for an important element in harm to bats and biodiversity. The study, “The economic impacts of ecosystem disruptions: Costs from substituting biological pest control,” published in Science, concludes with a finding  that “insect-eating bat population levels induce farmers to substitute with insecticides, consequently resulting in a negative health shock to infant mortality.” Daily News will cover this study in depth in an upcoming edition. According to research published in the Journal of the Association of Environmental and Resource Economists (2022), bat population declines cost American farmers as much as […]

(Beyond Pesticides, September 6, 2024) A literature review in the Internal Journal of Molecular Sciences provides promising insights into biofungicides as a “sustainable and economically viable alternative” to synthetic fungicides in expanding organic agriculture. The authors note that organic “… is the most sustainable response to current crises of all kinds, as it can better anticipate and prepare for crises and create long-term equity and resilience in food systems.” The authors point out that fungal infections in crops are estimated to account for 20-40% of failures annually, and understanding how to control such agricultural diseases will be crucial to meeting the needs of a growing global population. Organic farmers and land managers note that biological tools can be integrated into practices that work with the ecosystem, rather than be utilized as “substitute” products or controls with practices that ignore soil health and beneficial organisms that enhance biodiversity and provide ecosystem services (see here and here). Conducted by researchers in Mexico, the review examines data on biosynthesis (how plants create their own fungicide, known as secondary metabolites or SMs); the mechanisms of action of secondary metabolites against phytopathogenic (plant-killing) fungi; extraction techniques and biofungicide formulations; the biological activity of plant extracts on phytopathogenic fungi; and […]

(Beyond Pesticides, September 5, 2024) As insect-borne diseases like EEE (eastern equine encephalitis) become a focus of mosquito managers, there is a continuing pattern of mosquito resistance to synthetic pyrethroid insecticides, which are the primary tools in conventional mosquito control programs—a strategy more focused on attempting to kill adult mosquitoes than the management of breeding sites. A study published in PLOS One documents Aedes aegypti mosquito resistance to synthetic pyrethroids permethrin, lambda-cyhalothrin, and deltamethrin in study sites in Córdoba, Colombia. Aedes aegypti is a common mosquito species that can carry the EEE virus and others. There is significant scientific literature highlighting the prevalence of pesticide resistance in mosquito, fly, and other insect populations. Pesticide resistance is an inherent problem with pesticide dependency generally, creating a complex fabric of threats from insect resistance to plant incorporated protectants (PIPs), weed resistance in genetically engineered crop production dependent on chemical-intensive weed control, to antibiotic resistance to medically important drugs, exacerbated by agricultural use and horizontal gene transfer. As the frequency of deadly mosquito vector diseases is expected to increase with rising temperatures and greater precipitation—which raises the number of breeding sites—advocates, physicians, beekeepers, and community leaders are calling on elected officials to prioritize ecological […]

(Beyond Pesticides, September 4, 2024) A study in the Journal of Environmental Science and Public Health adds to the body of science that highlights the ecological decline threatening all species as a result of hazardous chemicals in the environment. “When environmental changes undermine a species’ or population’s ability to survive, it is said to be in an ecological crisis,” the authors state. They continue, “Pesticides, particularly persistent organic pollutants (POPs), are among the top ten chemicals and hazardous compounds that the WHO [World Health Organization] has recognized as being a concern for global health. The overuse and improper handling of agrochemicals is the primary driver of the ecological disaster.”   The researchers, from the Post Graduate Institute of Medical Education and Research in India, conducted a literature review to look broadly and comprehensively at the range of factors that contribute to adverse health effects (from breast cancer to genotoxic effects, chronic kidney disease, neurotoxicity, and more). They searched PubMed and Google Scholar for studies between 2004-2024 for relevant information on soil health, sustainable agriculture, food security, soil security, and the associations with human health. Their scientific findings lead the authors to conclude that the building of healthy soils will eliminate the need […]

(Beyond Pesticides, September 3, 2024) A piercing investigative article in the August 14 New York Times by journalist Greg Donahue reveals the abandonment of a group of brain disease patients in an area of Canada with forestry management for paper products, agriculture, and large amounts of pesticide use, including glyphosate. It illustrates the tension in the relationship between government authorities, regulated industries, and neurologist (physician) on the front lines. The article details the manner in which health officials appeared to manipulate their own investigation of a disease cluster to make it less disruptive to the economy of the Canadian province of New Brunswick. (This Beyond Pesticides analysis, where not otherwise indicated, draws on Mr. Donahue’s article.) New Brunswick has one major town, Moncton, and a large rural area characterized by agriculture and forestry. The province’s agriculture industry is dominated by blueberry production, which occupies the fourth largest amount of agricultural land in New Brunswick. About half the province is forested, with increasing amounts of land devoted to tree plantations intended for paper production. Glyphosate is hands-down the most heavily used pesticide in New Brunswick forestry, and New Brunswick is second only to Ontario in Canada’s total area of glyphosate-treated forest. […]

(Beyond Pesticides, August 28, 2024) The U.S. Environmental Protection Agency’s (EPA) pesticide labeling requirements fail to adequately communicate acute toxicity levels to the public, as evidenced in a recent study of consumers published last month in the journal Nature. After evaluating whether the current three “signal” words (CAUTION, WARNING, DANGER) on pesticide products adequately convey pesticide toxicity, the authors conclude that current labeling may result in “unintended adverse effects” because it does not “effectively communicate toxicity risks to consumers.” The signal words on pesticide labels, based on laboratory animal testing for determining lethal doses, are intended to protect users of the product from exposure that can kill through inhalation, skin absorption, and ingestion of the pesticide. However, the signal words do not warn about long-effects like cancer, neurological diseases, reproductive harm, as well as other adverse effects associated with pesticide exposure. (See Pesticide-Induced Diseases Database.)   The study tests two prototype labels to evaluate the effectiveness of visual elements in communicating toxicity information, citing research in cognitive psychology that indicates visual elements, like images and graphics, are more effective for conveying information than text alone. This is particularly crucial for pesticide labels, where complex toxicity details need to be communicated quickly […]

(Beyond Pesticides, August 26, 2024) In July, the U.S. Environmental Protection Agency (EPA) announced it was raising the allowable levels of the highly toxic weed killer atrazine in the nation’s waterways from the 2016 level of 3.4 to 9.7 micrograms per liter (µg/L), which scientists and environmental advocates say is a serious threat to aquatic plants, fish, invertebrates, and amphibians, in addition to people who recreate in waterways or eat food from them. With EPA’s August 7 decision to ban the weed killer Dacthal (or DCPA–dimethyl tetrachloroterephthalate), Beyond Pesticides is rallying public support for the removal of atrazine from the market under the same standards of harm, inability to mitigate hazards, and the availability of alternatives. As Beyond Pesticides points out in its 2022 atrazine comments (2020 and 2016 comments included) to EPA, the agency in November 2021 released the final Biological Evaluation (BE) assessing risks to listed species from labeled uses of atrazine (in the triazine chemical family). The agency made “likely to adversely affect (LAA) determinations” for 1,013 species and 328 critical habitats, which it is now rejecting, while using a “community-equivalent level of concern (CE-LOC)” measure that is filled with uncertainty and lacks any sense of precaution with […]

Image: Art Page submission from Sara Grantham, “Sunflower Pollinators”  (Beyond Pesticides, August 23, 2024) A study in Science of The Total Environment calculates and compares pesticide risk in 594 wild bee species associated with crops in North America. Current pesticide risk assessments that analyze effects on bees primarily focus on a limited subset of species and do not provide comprehensive protection of all wild bees. “Species commonly proposed as models for pesticide risk assessments may not accurately represent risk for those bee species facing the highest potential risk in agricultural contexts,” the authors postulate. The researchers continue, “This study presents a novel approach to characterize and compare the relative potential pesticide risk among wild bee species of their association with crops in North America using suites of intrinsic bee traits to quantify species’ vulnerability and extrinsic factors based on the toxic load of crops for bees and the strength of each species’ association with those crops.” In considering multiple factors that vary by species and determining potential harm to each from pesticide exposure, this study highlights the inadequacies of the current risk assessment process used by the U.S. Environmental Protection Agency (EPA).    The system for risk assessment for pesticides that […]

(Beyond Pesticides, August 22, 2024) A screening and analysis of 36 pesticides finds traces of these chemicals in patients with “unexplained chronic kidney disease” from agricultural communities in the Indian province of Uttar Pradesh. Researchers conducting this study, published in the Journal of Toxicology and Environmental Health Sciences, identify organophosphates, organochlorines, and pyrethroids as the main culprits, building on years of existing research pointing to adverse health impacts originating from bioaccumulation of pesticides after acute and chronic exposure. Chronic kidney disease (CKD) is a condition that afflicts one in ten adults internationally, based on a peer-reviewed analysis from The Lancet. The Centers for Disease Control and Prevention (CDC) estimate that one in seven U.S. adults (or roughly 35.5 million people) have CKD, with as many as nine in ten adults with the disease undiagnosed, based on 2023 data. The correlation between high rates of CKD and multigenerational use of and reliance on pesticides for food production, lawn care, and general land management reinforces the calls of advocates, farmers, and health professionals to adopt a new approach rooted in organic principles. Methodology This study was conducted by a group of researchers from the Department of Chemistry at Babu Banarasi Das University […]