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Study Finds That Antibacterial Enhances Endocrine Disruption

Wednesday, January 9th, 2008

(Beyond Pesticides, January 9, 2008) Triclocarban, an antibacterial compound widely used as an additive to a range of household and personal care products including bar soaps, detergents, body washes, cleansing lotions, and wipes, has been found to have an amplification effect on the activity of natural hormones, which in turn can lead to adverse reproductive and developmental effects. In the study, published online November 29, 2007 in Endocrinology, researchers from University of California- Davis and Yale University investigated the endocrine disrupting properties of triclocarban and other polychlorinated diphenyl urea compounds by exposing human cells and rats to levels similar to those found in people. Triclocarban was found to have a synergistic interaction with the sex hormone, testosterone- present in both males and females. This interaction produced a positive, amplified biological effect, which is likely to hyperstimulate native sex hormones. This amplification of sex hormone activity occurs at the target cell and can result in developmental defects or decreased reproductive function. Researchers further explained that ovulation and ovarian function in females can be disrupted, while sperm quality can be decreased in males. The researchers also point out that the results of their study create a new category for endocrine disruptive substances […]

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Study Finds Triclosan Concentrations Highest Among the Wealthy

Friday, December 14th, 2007

(Beyond Pesticides, December 14, 2007) A study recently published in Environmental Health Perspectives has found concentrations of the antibacterial chemical triclosan in a high percentage of subjects tested. Used in common household products like plastics, personal care products, and textiles, exposure routes are becoming difficult to avoid. According to the report’s summary, “Concentrations differed by age and socioeconomic status but not by race/ethnicity and sex. Specifically, the concentrations of triclosan appeared to be highest during the third decade of life and among people with the highest household incomes.” The study analyzed urine samples from 2,517 individuals, age 6 and over. Annual household income ranged from less than $5,000 to $75,000, and three major self-reported racial/ethnic groups were non-Hispanic black, non-Hispanic white, and Mexican American. Of the 2,517 urine samples, 74.6 percent contained triclosan. However, “the frequency of detection of triclosan varied by income group (63.7% [$20,000-$45,000]; 78.7% [$45,000]).” The report discussed the high levels of detection: “We detected concentrations of free plusconjugated species of triclosan in urine in 74.6% of the samples examined. This high frequency of detection is most likely associated with daily use by the US general population of consumer products that contain triclosan, including at least one […]

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With Antibiotic-Resistant Bacteria on the Rise, Study Confirms Risks of Antibacterial Soaps

Friday, October 19th, 2007

(Beyond Pesticides, October 18, 2007) Antibacterial soaps show no health benefits over plain soaps and, in fact, may render some common antibiotics less effective, says University of Michigan public health professor Allison Aiello, Ph.D. The study, “Consumer Antibacterial Soaps: Effective or Just Risky?” appears in the August edition of Clinical Infectious Diseases. In the first known comprehensive analysis of whether antibacterial soaps containing triclosan work better than plain soaps, Dr. Aiello of the University of Michigan School of Public Health and her team found that washing hands with an antibacterial soap was no more effective in preventing infectious illness than plain soap. Moreover, antibacterial soaps at formulations sold to the public do not remove any more bacteria from the hands during washing than plain soaps. Because of the way triclosan, the main active ingredient in many antibacterial soaps, reacts in the cells, it may cause some bacteria to become resistant to commonly used drugs such as amoxicillin, the researchers say. These changes have not been detected at the population level, but e-coli bacteria bugs adapted in lab experiments showed resistance when exposed to as much as 0.1 percent weight/volume triclosan soap. “What we are saying is that these e-coli could […]

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Scientists Say Soap and Water Beat Antibacterials

Friday, January 26th, 2007

(Beyond Pesticides, January 26, 2007) With an annual introduction of 200 to 300 new anti-microbial products, scientists are saying that the most effective way to fight germs is the old fashioned way””soap and water. Amid a national trend of increasing germophobia, experts are saying soap and water are a better option than alcohol-based disinfectants and antibacterial soaps. In 2005, the U.S. Food and Drug Administration led a panel of experts and industry representatives to weigh and analyze different germ killing methods. The panel found “no firm scientific evidence that the flood of antimicrobial products we observe has any discernible benefit over the use of regular soap and water.“ Few people are aware that plain soap is an anti-microbial. It kills bacteria by making their cell membranes leak fluids. This coupled with the motion of scrubbing the hands together””which loosens microbes and makes them fall into the soapy solution and wash away””creates “one of the most critical control strategies” for germs, according to the U.S. Centers for Disease Control and Prevention. According to Mike Richardson, an industry analyst at the Freedonia Group in Cleveland, consumers spend more than $200 million on anti-microbial products every year. With sanitizers being used on shopping […]

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