(Beyond Pesticides, October 18, 2007) In a scholarly review written by Theo Colborn, Ph.D. and Lynn Carroll, Ph.D., the authors point to the multigenerational effects of some pesticides that they say demand improved regulation to protect human and environmental health. The review, “Pesticides, Sexual Development, Reproduction, and Fertility: Current Perspective and Future Direction,” appears in the international journal Human and Ecological Risk Assessment (13:5, 1078 — 1110), September, 2007. The study points out a major deficiency in the U.S. Environmental Protection Agency’s regulation of pesticides under current health reviews and risk assessments. The authors call EPA’s pesticide registration system “outmoded” and one that has “almost completely missed the low-dose and endocrine system-mediated effects of pesticides.” The study reviews both epidemiological and laboratory data. In the abstract, the authors state the following: Improvements in chemical analytical technology and non-invasive sampling protocols have made it easier to detect pesticides and their metabolites at very low concentrations in human tissues. Monitoring has revealed that pesticides penetrate both maternal and paternal reproductive tissues and organs, thus providing a pathway for initiating harm to their offspring starting before fertilization throughout gestation and lactation. This article explores the literature that addresses the parental pathway of exposure […]

(Beyond Pesticides, September 24, 2007) Seven representatives wrote to the EPA last Thursday, urging the government agency to act promptly to identify and screen products for dangerous endocrine-disrupting chemicals. The letter asks EPA Administrator Stephen Johnson to provide definite deadlines in the testing and control of endocrine disruptors, which are substances that interfere with the normal functioning of the endocrine system, responsible for hormonal and developmental processes. EPA’s regulation of these substances that mimic or alter natural hormonal processes has been slow and lacks direction to meet set goals promptly, according to the U.S. Representatives. “To date, EPA’s efforts in this area have been characterized by missed deadlines, prolonged delays, and inadequate incorporation of public input,” according to the letter from the House Committee on Oversight and Government Reform, chaired by Rep. Henry Waxman (D-California). Ranking Minority Member on the Committee Tom Davis (R-Virginia); Representatives Elijah Cummings (D-Maryland), Chris Van Hollen (D-Maryland), Wayne Gilchrest (R-Maryland), and Jim Moran (D-Virginia); and Delegate Eleanor Holmes Norton (D-D.C.) also signed the letter to EPA. Advocates say that EPA’s lack of urgency on endocrine disruptors leaves the American population and future generations at risk for adverse health effects from exposure to these substances through […]

(Beyond Pesticides, September 18, 2007) On September 16, 2007, researchers from the National Institute of Environmental Health Sciences presented findings to the European Respiratory Society Annual Congress in Stockholm showing that exposure to several commonly used pesticides increases the risk of asthma in farmers. Pesticide exposure is a “potential risk factor for asthma and respiratory symptoms among farmers,” lead author Dr. Jane A. Hoppin told Reuters Health. “Because grains and animals are more common exposures in agricultural settings, pesticides may be overlooked. Better education and training of farmers and pesticide handlers may help to reduce asthma risk.”The study consisted of 19,704 farmers, 441 of which had asthma. Farmers who have experienced high pesticide exposure were twice as likely to have asthma. Sixteen of the pesticides studied were associated with asthma. Coumaphos, EPTC, lindane, parathion, heptachlor, 2,4,5-TP, DDT, malathion, and phorate had the strongest effect. “This is the first study with sufficient power to evaluate individual pesticides and adult asthma among individuals who routinely apply pesticides,” Dr. Hoppin said. Asthma is a serious chronic disorder of the lungs characterized by recurrent attacks of bronchial constriction, which cause breathlessness, wheezing, and coughing. Asthma is a dangerous, and in some cases life-threatening disease. […]

(Beyond Pesticides, September 4, 2007) Scientists identified an important biochemical piece in the passage of malaria from mosquitoes to humans. If this link in the chain can be broken at its source””the mosquito””then the spread of malaria could be stopped without the use of harmful pesticides or costly drugs. “Mosquito Heparan Sulfate and Its Potential Role in Malaria Infection and Transmission,” published in the August 31 issue of the Journal of Biological Chemistry, contains the findings of the interdisciplinary team led by researchers from Rensselaer Polytechnic Institute. The research group found that humans and the mosquitoes that carry the malaria parasite Plasmodium share the same complex carbohydrate, heparan sulfate. In both humans and mosquitoes, heparan sulfate is a receptor for the Plasmodium, binding to the parasite and giving it quick and easy transport through the body. Robert J. Linhardt, Ph.D., professor of Biocatalysis and Metabolic Engineering at Rensselaer, led the team. “The discovery allows us to think differently about preventing the disease. If we can stop heparan sulfate from binding to the parasite in mosquitoes, we will not just be treating the disease, we will be stopping its spread completely,” Dr. Linhardt said. Malaria parasites are specific to their host, […]

(Beyond Pesticides, August 20, 2007) Environmental groups launched a public campaign last Wednesday to urge state officials to stop applying toxic herbicides for vegetation control along state roadways. Members of the Massachusetts Coalition for Pesticide Reduction maintain that herbicides, which the state resumed using in 2003, are harmful to people and the environment. Sylvia Broude, community organizer for Toxics Action Center, said toxic chemicals such as the ones the Highway Department uses can harm more than just the intended target. The chemicals can run off highways, pollute drinking water and eventually lead to health problems in humans, ranging from eye problems and learning disabilities to some forms of cancer, she said. The group is asking the state to use organic herbicides or manual means, such as weed whackers or lawnmowers, which the state used exclusively in the early 2000s. But state officials say affected areas are in small, controlled environments. The Highway Department says that it removes unwanted bushes and weeds manually or mechanically on the vast majority of the 48,200 acres it maintains but needs the herbicides for about 188 acres, less than half of 1 percent of the total. Spokesman John Lamontagne said removing weeds mechanically in some […]

(Beyond Pesticides, August 17, 2007) The widespread presence of pesticides and other agricultural runoff has been confirmed in the world’s largest coral reef system. Degradation of the system threatens not only a natural treasure but also the region’s economy. Australia’s Great Barrier Reef is the subject of a recent report by the Great Barrier Reef Marine Park Authority. Entitled the “Annual Marine Monitoring Report 2006,” the study confirms extensive contamination in eight of the ten major tributaries into the marine park, much of which is fertilizer and pesticide runoff from the area’s farmland. Local environmental groups are calling for government protection of the reef from these pollutants, and tourism interests worry that damage to the reef will reduce the number of visitors to Australia. According to World Wildlife Foundation-Australia program leader Nick Heath, “Reducing pollution load is possible and will help us save the Reef, as well as the 60,000 tourism jobs based around the Reef.” According to the report, “Water quality in the Great Barrier Reef is principally affected by land-based activities in its adjacent catchments, including vegetation modification, grazing, agriculture, urban development, industrial development and aquaculture. Nutrients, sediments and pesticides are the pollutants of most concern for the […]

(Beyond Pesticides, August 9, 2007) China reports it is cracking down on the use of recently banned pesticides and is taking additional actions in an effort to counter concerns about the country’s food safety. The major exporter has been the subject of frequent reports of contaminated products, including several foods imported by the U.S. Reuters reports that according to a new poll, U.S. consumers are extremely wary of products made in China, and nearly two-thirds said they would support a boycott of Chinese goods. In reaction to the potential loss of export markets and the upcoming Beijing Olympics, China says it will spend more than $1 billion improving food and drug safety over the next three years. The Chinese government will specifically launch a campaign to crack down on the use of banned pesticides that are still being manufactured and remain in use. The campaign is in response to news reports that “a dozen or so” pesticide producers were still making highly poisonous pesticides such as methylamine and phosphamidon. Prior to the recent ban, 1,500 pesticide manufacturers, approximately half of the industry, produced the chemicals. However, pesticides that are still approved for use in China are also raising concerns as […]

(Beyond Pesticides, August 7, 2007) In a study that examines the influence of age of exposure on the magnitude of the association between DDT and breast cancer risk finds that women who were exposed to DDT before the age of 14 are five times more likely to develop breast cancer later in life. In contrast, the study finds exposure after adolescence does not increase risk. The data used in the study targets the age of a woman in 1945 as an indicator for the youngest possible age for a woman to be exposed to DDT, since DDT was first introduced to the U.S. for mosquito control in 1945. The researchers, from the Center for Research on Women’s and Children’s Health, Public Health Institute at Berkeley, California and the Mount Sinai School of Medicine, analyzed blood that had been collected from women between 1959 and 1967 – years during which the use of DDT was at its highest. “DDT and breast cancer in young women: New data on the significance of age at exposure,” published last week in the online edition of the journal Environmental Health Perspectives, is “the first study specifically designed, a priori, to consider whether age at exposure […]

(Beyond Pesticides, July 31, 2007) Preliminary research into birth records and pesticide data reveal that mothers who were within 500 meters of fields sprayed with organochlorine pesticides during their first trimester of pregnancy were six times higher to have children with autism compared to mothers who did not live near the fields. Scientists from the California Department of Public Health conducted the study, which is available online in Environmental Health and Perspectives, entitled, “Maternal Residence Near Agricultural Pesticide Applications and Autism Spectrum Disorders Among Children in the California Central Valley.” The study, initiated to “systemically explore the general hypothesis that residential proximity to agricultural pesticide applications during pregnancy could be associated with autism spectrum disorders in offspring,” found that 28% of the mothers studied who lived near fields in Central Valley, which were sprayed with organochlorines, such as endosulfan and dicofol, have children with autism. However, officials are quick to point out that their findings are preliminary. “We want to emphasize that this is exploratory research,” says Dr. Mark Horton, M.D., director of the California Department of Health. “We have found very preliminary data that there may be an association. We are in no way concluding that there is a […]

(Beyond Pesticides, June 29, 2007) On June 28, 2007, forty years after it received protection under the Endangered Species Act (ESA) and thirty-five years after the banning of DDT in the U.S., the bald eagle was removed from the ESA’s “threatened” list. Bald eagle populations declined dramatically in the last century, attributed mostly to the accumulation of the pesticide DDT in fish, a staple of the eagle’s diet. The pesticide gradually poisoned females, causing them to produce thinly-shelled eggs that broke easily, preventing the embryos from growing. Years of hunting, accidental poisoning and habitat loss took an additional toll. “The rescue of the bald eagle from the brink of extinction ranks among the greatest victories of American conservation.” said John Flicker, President of the National Audubon Society. “Like no other species, the bald eagle showed us all that environmental stewardship has priceless rewards. In every state, parents and grandparents can still point to the sky and share a moment of wonder as a bald eagle soars overhead.” The U.S. Fish and Wildlife Service (FWS) in 1967 listed the bald eagle as endangered, a designation that gave the bird legal protection from harmful human activities and in 1972, the U.S. Environmental […]

(Beyond Pesticides, June 8, 2007) New research shows that pesticides can reduce the efficiency of nitrogen-fixing plants, impacting soil fertility and ultimately reducing crop yields. The insecticides methyl parathion, DDT and pentachlorophenol were among the chemicals found to inhibit or delay the symbiotic relationship between the legume alfalfa and rhizobia bacteria, which is crucial to nitrogen fixation. Legume crops are often cultivated to help replenish the vital soil nutrient nitrogen (N), but legumes cannot achieve this on their own — Rhizobium bacteria interacts with legumes to convert atmospheric N to nutrient compounds utilizable by plants. Legumes like alfalfa and soybeans are often included in crop rotations due to this beneficial relationship. Nitrogen fixation resulting from the symbiotic relationship between leguminous plants and species of Rhizobium bacteria is an ecological service estimated to be equivalent to $10 billion worth of synthetic N fertilizer annually. Symbiotic nitrogen fixation (SNF) reduces the need for synthetic fertilizers, which cause environmental problems such as impaired water quality. Acknowledging that SNF is both initiated and maintained by chemical signals between the host plant and the beneficial bacteria, the research team postulated that natural and synthetic chemicals could disrupt these signals. The study shows “previously undescribed in […]

(Beyond Pesticides, May 25, 2007) Rachel Carson, a timely and key voice responsible for warning the public about the dangers of chemical pesticides, would be turning 100 this weekend. Despite succumbing to breast cancer in 1964, her legacy lives on – Rachel Carson’s fight continues today, as her work is more relevant than ever. Rachel Carson authored the seminal book of the modern environmental movement, Silent Spring, published in 1962. The book detailed detrimental effects of pesticides on the environment, focusing on bird decline and DDT use. Her message had and continues to have a profound effect, calling on people to think beyond wilderness conservation efforts when protecting the environment – to think about what is happening in every ecosystem, including our own backyards. Silent Spring was instrumental in setting off a chain of events, including Earth Day and the formation of the U.S. Environmental Protection Agency, which subsequently banned almost all DDT use in 1972. Despite all of the honors, awards and praise that have been given in the memory of Rachel Carson, her cause continues to be controversial, especially regarding the dangers of DDT. The latest row has surfaced over claims that the decline in DDT use internationally […]

(Beyond Pesticides, May 22, 2007) In a study published in the latest issue of Environmental Toxicology and Chemistry, scientists found that seafood products from southern China contain high concentrations of DDT and hexachlorocylohexane (HCH). While banned in China since 1983, humans are being exposed to organochlorine pesticides (OCP) at rates high enough to pose health threats. The study responded to high rates of DDT and HCH found in sediment, water and biota in the Pearl River delta and neighboring coast, where land is being rapidly industrialized, urbanized, and transferred from agriculture to commercial development. Researchers tested 212 seafood products, including shrimp, crabs, and mollusks, from 11 coastal cities for 21 OCPs, including DDT, HCH, heptachlor, dieldrin, and endosulfan. The highest concentrations of DDT were found in four species of shellfish, although concentrations varied widely depending on sampling location. The study reported, “These results suggest that bioaccumulation of DDTs in seafood products was highly species-specific, probably due to different feeding habits and habitats.” By taking a large sample of one indicator species, it also concluded “the coastal region of southern China is probably one of the most DDT-polluted areas in the world.” Researchers also found HCH to be more widely prevalent […]

(Beyond Pesticides, April 25, 2007) Public health and environmental activists call on the world community today to respect life, protect children, stop hazardous pesticide use, including DDT, and adopt what they call “sustainable programs that attack poverty and the conditions that give rise to insect-borne diseases such as malaria.” Africa Malaria Day is commemorated on April 25, a day set aside by African governments committed to rolling back malaria and meeting the United Nations malaria-related Millennium Development Goals. Last September, the World Health Organization came under heavy criticism from public health and environmental groups when it announced its new policy to promote the use of DDT for malaria control in developing countries. Environmental and public health advocates warn that good intentions are in this case misguided. According to the Washington, DC-based non-profit organization Beyond Pesticides, advocating a reliance on pesticides, especially DDT, as a silver bullet solution for malaria protection is extremely dangerous. When the underlying causes of pest problems are not adequately addressed, then a sustained dependence on toxic pesticides like DDT causes greater long-term problems than those that are being addressed in the short-term. “The WHO is misleading the world on DDT, which is a known cancer causing […]

(Beyond Pesticides, April 20, 2007) As we celebrate Earth Day this weekend, Beyond Pesticides would like to take this moment to reflect on exactly where pesticides fit into the current environmental picture, including victories of the past and victories needed for a healthy future. Over the last year, the organic movement has seen many successes, with school pesticide reduction victories in North Carolina, Utah, Virginia, and California; new organic parks in New Jersey; increasing numbers of sustainable vegetable and cotton growers; and even hospitals and schools purchasing organic food. As we celebrate these victories, we look ahead to ways we can continue this trend toward organics, and opportunities for connecting with other environmental causes. Global climate change is the major focus of Earth Day this year, as well as a major focus of the environmental movement as a whole. But rather than being a separate issue from pesticides, the two are actually very much related. In fact, the Rodale Institute has figured organic farming requires 63% less energy (fossil fuels) than “conventional” methods. Top this off with the fact that industrial agricultural methods also reduce the amount of carbon that can be sequestered in soil, and the organic connection becomes […]

(Beyond Pesticides, April 10, 2007) Scientists have reported several environmental estrogens can affect the immune system, promoting allergic diseases such as asthma. Researchers have observed this response using pesticides and other environmental contaminants. Focusing on six environmental estrogens (xenoestrogens), researchers were able to reveal how these contaminants affect the immune system. Using doses representative of present human exposures, these estrogen-mimics were tested on human and mouse cells. The observed effect of exposure was both an increase in speed and intensity of immune reactions. Three of the environmental estrogens tested were organochlorine pesticides or metabolites: endosulfan, dieldrin and DDE (DDT metabolite). The other contaminants included nonylphenol, a by-product of plastics manufacturing, and two PCBs. The study reveals that the accelerated and increased level of degranulation of mast cells is the mechanism that causes more severe allergic reactions than would otherwise take place. According to Environmental Health News, mast cells play a vital role in allergic reactions because they are primed by past experience with allergens to release inflammatory agents into the body, which causes an allergic reaction. If the mast cell has been primed to react to a specific allergen, it will degranulate, releasing molecules such as histamine. The more intense […]

(Beyond Pesticides, March 30, 2007) A committee of experts advising the United Nations Environment Programme and the Food and Agriculture Organization (FAO) has recommended adding endosulfan and tributyl tin compounds (TBT) to a list of substances that are considered so harmful they can only be traded in special circumstances. On March 27, 2007, the United Nations said that the toxic chemicals would only be allowed to be exported to countries that have explicitly chosen to permit them, a measure aimed at protecting humans and the environment in developing countries. Endosulfan, a chemical sprayed onto food crops and cotton, and TBT, used in “antifouling paint” for ships’ hulls, are already banned in many countries. However, they may be traded freely in countries lacking tight environmental regulations. According to David Santillo who works at the research center for Greenpeace at Britain’s Exeter University, “It’s great that these two have been added to the list so countries have the choice whether to import them or not.” Endosulfan has been linked with testicular cancer, prostate cancer, breast cancer, and defects in male sex organs. According to a recent study conducted in Costa Rica’s mountain forests, findings show that surprisingly high concentrations of pesticides are […]

(Beyond Pesticides, March 2, 2007) The United States Department of Agriculture’s (USDA) Pesticide Data Program (PDP) recently released its latest annual summary detailing pesticide residues in the U.S. food supply. The data, from 2005, reveals approximately two-thirds of sampled foods contained one or more pesticides at detectable levels. For the 2005 report, PDP sampled fresh and processed fruit and vegetables, soybeans, wheat, milk, heavy cream, pork, bottled water and drinking water. A total of 14,749 samples were tested for various insecticides, herbicides, fungicides and growth regulators. Twelve states reported data to comprise the report: California, Colorado, Florida, Maryland, Michigan, Minnesota, Montana, New York, Ohio, Texas, Washington and Wisconsin. Excluding drinking water, 84 percent of samples originated within the United States. Foods most likely to be consumed by infants and children are analyzed to provide data that is used in the implementation of the Food Quality Protection Act. The data is used in this context to assess dietary exposure to pesticide residues by the Environmental Protection Agency (EPA). Overall results show that, excluding drinking water samples, 36 percent of samples had more than one detectable pesticide, 30 percent had one detectable pesticide, and 34 percent did not have detectable levels of […]

(Beyond Pesticides, February 1, 2007) Thirty-five years after the banning of DDT, extremely high concentrations of the pesticide are being found in fish caught in California’s Los Angeles county waters. According to a newly released federal survey by the National Oceanic and Atmospheric Administration (NOAA) and Environmental Protection Agency (EPA), the fish caught in the area contain the world’s highest-known DDT concentrations. The survey was conducted in order to update health advisories on which fish are unsafe to eat and to help EPA decide whether to attempt a costly operation to reduce continued contamination from a deposit of DDT on the ocean floor. The findings contradict the belief held by some scientists that DDT on the ocean floor has been breaking down into less-toxic compounds and would soon disappear from marine life. The contamination, most severe in the middle of San Redondo Bay, stems from a 100-ton deposit of DDT released by the Montrose Chemical Co. beginning in the late 1940s, which still covers several square miles of the ocean floor. The pesticide manufacturer had a plant near Torrance, California, from 1947 to 1971, releasing about 2,000 tons of DDT into county sewers that subsequently emptied into the ocean. The […]

(Beyond Pesticides, January 30, 2007) Breast cancer groups across the country have a new issue to add to the repertoire of risk factors: Pesticide use. A study published online in the American Journal of Epidemiology has found a strong link between residential pesticide use and breast cancer risk in women. Responding to the study, Susan Teitelbaum, Ph.D., assistant professor in the department of community medicine at the Mount Sinai School of Medicine in New York, says the options are simple”” “Stop using pesticides.” The study, published December 13, is the first to examine the relation between breast cancer and pesticides through self-reported residential pesticide use. Using women from New York, the study looks not at one or two incidents of pesticide contact, but at the impact of lifelong pesticide use in the home, lawn and garden. Using a sample of 1,508 women who were diagnosed with breast cancer between 1996 and 1997, the study compares these women to 1,556 control subjects who were randomly selected. The results show that those women whose blood samples had higher levels of organochlorines are at an increased risk of breast cancer. Organochlorines are a broad class of chemicals, including DDT, dieldrin, and chlordane, and […]