Research Shows Commonly Used Pesticides Produce Greater Toxic Effect When Mixed
Thursday, August 11th, 2011(Beyond Pesticides, August 11, 2011) A combination of eleven different kinds of commonly used pyrethroids were tested on mice in a new study which found that, at real-world exposure levels, the insecticides can produce heightened toxicity that is equal to the sum of each insecticide’s individual effect. The mixture of similar-acting insecticides works by over-stimulating electronic channels in the mouse’s brain cells and eventually causing death. This study adds to the growing body of research on the toxicity of pesticide combinations in nature and showcases the need for policy change because the current risk assessment approach to regulating pesticides fails to look at chemical mixtures and synergistic effects. The U.S. Environmental Protection Agency (EPA) currently regulates on a chemical-by-chemical basis, but as this study demonstrates, interacting chemicals can have synergistic effects at very low levels, where a “chemical cocktail” of multiple interacting chemicals combine to have greater effects than expected. Pesticides can also have a cumulative “toxic loading” effect both in the immediate and long term. Researchers exposed mice brain cells to eleven different food-use pyrethroid insecticides either singly or in a mixture in the study entitled ”Additivity of pyrethroid actions on sodium influx in cerebrocortical neurons in primary culture.” […]
