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Pesticide Exposure Driving Liver Disease through Hormone Disrupting Mechanisms

Thursday, July 21st, 2022

(Beyond Pesticides, July 21, 2022) Research published in Scientific Reports finds an association between the increasing emergence of nonalcoholic fatty liver disease (NAFLD) and exposure to endocrine (hormone) disrupting chemicals, like organochlorine pesticides (OCPs). It is well-known that traces of legacy (past-use) pesticides, like organochlorines, remain in the environment for decades—possibly centuries, post-final application, as OCPs have greater chemical stability and gradual attenuation. However, these chemicals have profound adverse impacts on human health, especially on the endocrine system. Obesity, insulin resistance, type 2 diabetes, and elevated liver enzyme resulting from endocrine disruption contribute to NAFLD and can lead to liver cirrhosis. Although some, but not all, manufacturing and use of specific OCPs have declined in the U.S., OCPs remain a global issue, as much of the developing world still reports usage. Considering the lack of studies on OCP-induced endocrine disruption and NAFLD, research like this highlights the need to understand the underlying mechanisms that contribute to growing endocrine disease incidents.   The study determined that there is an association between OCP exposure and NAFLD using the fatty liver index (FLI), a predictor of lipid (fat) accumulation in the liver. The researcher collected blood serum to measure the concentration of OCPs, specifically evaluating detectable […]

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Take Action: Male Fertility Harmed by Pesticides and EPA Dysfunction

Monday, July 18th, 2022

(Beyond Pesticides, July 18, 2022) The failure of the U.S. Environmental Protection Agency (EPA) to meet its statutory responsibility to protect people and wildlife from the dire consequences of exposure to endocrine disrupting chemicals must end. A study published in Toxicology and Applied Pharmacology adds urgency to the need to eliminate endocrine-disrupting pesticides. The authors find that prepubescent exposure to endocrine-disrupting chemicals (EDCs), including pesticides, impairs male reproduction through the interruption of testicular homeostasis and development of reproductive Leydig cells, and can have multigenerational effects. This adds to the long list of scientific articles showing EPA neglect of the devastating effects of widely used pesticides. Tell EPA that pesticide use cannot continue without findings of no endocrine disruption. Tell Congress to ensure that EPA does its job. More than 50 pesticide active ingredients have been identified as endocrine disruptors that mimic the action of a naturally-produced hormone, such as estrogen or testosterone, thereby setting off similar chemical reactions in the body; block hormone receptors in cells, thereby preventing the action of normal hormones; or affect the synthesis, transport, metabolism and excretion of hormones, thus altering the concentrations of natural hormones. Endocrine disruptors have been linked to attention deficit hyperactivity disorder (ADHD), […]

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Endocrine-Disrupting Chemicals Impair Juvenile Male Fertility Development and Threatens Future Reproductive Health

Thursday, July 14th, 2022

(Beyond Pesticides, July 14, 2022) A study published in Toxicology and Applied Pharmacology finds prepubescent exposure to endocrine-disrupting chemicals (EDCs), including pesticides, impairs male reproduction through the interruption of testicular homeostasis and development of reproductive Leydig cells. Endocrine disruptors are xenobiotic (i.e., chemical substances like toxic pesticides foreign to an organism or ecosystem). Many reports demonstrate that exposure to endocrine-disrupting chemicals can adversely affect human, animal—and thus environmental—health by altering the natural hormones in the body responsible for conventional reproductive, physical, and mental development. Scientists and health officials already associate pesticide exposure with a decrease in male fertility, including reduced sperm count, quality, and abnormal sperm development. The presence of pesticides in the body has implications for human health, especially during vulnerable life stages, such as childhood, puberty, pregnancy, and old age. Therefore, it is essential to understand how exposure to toxic chemicals in the environment affects future reproductive success and health. The researchers note, “Recent studies revealed that exposures to EDCs during so-called critical windows of susceptibility (prenatal, prepubertal, pubertal, and aging periods) could disrupt healthy patterns of testes development and homeostasis, which can be demonstrated as an impaired testicular function later in life. However, much more work is needed to understand better the cellular […]

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First Report of Environmental Pollutant Risk Among Tropical Mammals Across the Globe

Thursday, May 5th, 2022

(Beyond Pesticides, May 5, 2022) A report published in Biological Conservation finds environmental pollutants, including pesticides, pharmaceuticals, plastics, and particulate matter, adversely affect tropical terrestrial wildlife. Specifically, these contaminants can interact with one another, altering the chemical landscape of the ecosystem, and causing changes in the endocrine and microbiome systems of mammals. Since the publication of Rachel Carson’s Silent Spring (1962), global attention to the danger of pesticides has increased, with environmental agencies banning the use of legacy pesticides like organochlorines for their devastating toxic—sometimes lethal—effects. However, these chemicals can remain in the environment for decades and interact with various current-use pesticides, including organophosphates, neonicotinoids, and pyrethroids. Although many studies demonstrate that environmental pollution plays a significant role in premature deaths among humans, there is a lack of research on how environmental pollution directly affects tropical species mortality. Considering human and wildlife habitats tend to overlap, and chemical pollutants can drift from chemically treated areas, wildlife populations are more likely to experience similar health effects. With the number of chemicals in the ecosystem growing, studies like these highlight the need for pesticide policies that protect human health in addition to the integrity of the chemical landscapes accommodating wildlife. The researchers note, “Using […]

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Plastic Sports Bottles Leach Thousands of Chemicals, including a Common Insect Repellent

Thursday, February 17th, 2022

(Beyond Pesticides, February 17, 2022) Reusable plastic sports bottles can leach hundreds of different chemical substances into water, including a range of plasticizers, endocrine disruptors and surprisingly, an insect repellent. Researchers at University of Copenhagen, Denmark recently published their findings in the Journal of Hazardous Materials, calling for caution in the use of these products. “We were taken aback by the large amount of chemical substances we found in water after 24 hours in the bottles. There were hundreds of substances in the water – including substances never before found in plastic, as well as substances that are potentially harmful to health. After a dishwasher cycle, there were several thousand,” says Jan H. Christensen, PhD, Professor of Environmental Analytical Chemistry at the University of Copenhagen’s Department of Plant and Environmental Sciences. Scientists used three types of reusable plastic sports bottles, split between newly purchased and bottles that had been in regular use before the experiment. Glass bottles were used as a control. First a migration experiment was conducted. Newly purchased bottles were rinsed with tap water (which was then disposed), and then refilled with tap water and stored for 24 hours. A second experiment placed all the bottles in the […]

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USDA Food Pesticide Residue Survey Raises Alarm, while Pesticide Industry and EPA Mislead Public

Friday, February 4th, 2022

(Beyond Pesticides, February 4, 2022) In January, the U.S. Department of Agriculture (USDA) issued its 30th Pesticide Data Program (PDP) Annual Summary report (which evaluates each year the presence of pesticide residues on produce) and misleads the public on the safety of food and agricultural practices. This 2020 report concludes that more than 99% of the produce samples tested showed residues below established U.S. Environmental Protection Agency (EPA) benchmark levels. At first blush, this sounds very reassuring, but Beyond Pesticides maintains that there is (always) more to the “safety” story, not least of which are serious deficiencies in EPA’s establishment of those “tolerances.” Those flaws include a lack of risk assessment for vulnerable sub-populations, such as farmworkers, people with compromised health, children, and perhaps, cultural/ethnic and regional sub-groups of the general population, and a failure to fully assess serious health outcomes such as disruption of the endocrine system (which contributes to numerous serious diseases). For everyone, Beyond Pesticides recommends choosing organic produce whenever possible — the vast majority of which does not contain synthetic pesticide residues. The PDP report asserts that “the data . . . illustrate that residues found in agricultural products sampled are at levels that do not pose […]

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Dr. Martin Luther King, Jr.’s Words, “All life is interrelated,” and His Legacy Are Honored on MLK Day, Monday, Jan. 17

Friday, January 14th, 2022

(Beyond Pesticides, January 14, 2022) On the annual celebration of the life and work of Dr. Martin Luther King, Jr.— MLK Day, Monday, January 17 — Beyond Pesticides honors his legacy by calling out ongoing environmental inequities, and calling on all of us to advance environmental justice. In his 1967 Christmas sermon, Dr. King famously noted, “It really boils down to this: that all life is interrelated. We are all caught in an inescapable network of mutuality, tied into a single garment of destiny. Whatever affects one directly, affects all indirectly.” There may be no better description of what is at stake in environmental justice work — righting environmental wrongs that have disproportionate impacts on some groups of people. In its attention to the multitude of ways in which BIPOC (Black, Indigenous, and People of Color) populations face disproportionate risks and impacts, Beyond Pesticides works to ensure that all people are afforded circumstances that support their safety, health, and well-being. Rather than excavate the very long historical record of environmental injustice in the U.S., today’s Daily News Blog recalls several examples from the past year. It is impossible to begin that chronicle without first acknowledging that the ongoing Covid-19 pandemic has […]

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Degenerative Lung Diseases Associated with Atrazine Exposure, Worsened in Combination with Common Cancer Treatment

Friday, December 3rd, 2021

(Beyond Pesticides, December 2, 2021) A study published in Cellular Physiology and Biochemistry finds atrazine (ATR) exposure worsens lung disease outcomes in individuals with idiopathic (spontaneous) pulmonary fibrosis (IPF), a group of incurable lung diseases involving damaged/scarred lung tissue. Furthermore, chemotherapeutic products used to treat lymphoma (immune system cell cancer) like bleomycin can induce pulmonary fibrosis complications exacerbated by pesticide exposure. However, pesticide-related pulmonary fibrosis can have implications for neurological health, such as motor function. Scientific literature already finds an association between pesticide exposure and respiratory illnesses such as asthma, lung cancer, and chronic obstructive pulmonary disease (chronic bronchitis). Although IPF impacts over 5 million people a year globally, the disease is difficult to predict, which is concerning as the death rate is 50 to 56 percent within the first few years. Therefore, studies like this highlight the significance of evaluating how pesticide exposure impacts respiratory function, especially when exposure to respiratory toxicants increases vulnerability to existing respiratory-fixated illnesses like Covid-19. Advocate have urged the U.S. Environmental Protection (EPA) to incorporate scientific findings that these—where chemical exposures exacerbate an existing medical condition—into its pesticide registration review program. Researchers note, “[O]ur data represent an addition to the complex information on ATR-induced pulmonary toxicity. In particular, in this […]

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Banned Pesticides Associated with Endometriosis

Wednesday, December 1st, 2021

(Beyond Pesticides, December 1, 2021) Women exposed to metabolites of the banned insecticide chlordane are over three times more likely to develop endometriosis, finds research published in the journal Environment International. The study is the latest to find links between persistent organic pollutants (POPs), still lingering in our environment and in our bodies, and chronic disease. According to an economic analysis conducted in 2016, exposure to endocrine (hormone) disrupting chemicals, often implicated in considerable damage to the body’s reproductive system, results in billions of dollars of health care costs from female reproductive disorders. Researchers set out to integrate two methodologies into their evaluation, combining analysis of POP biomarkers in blood with an analysis of biomarkers in that body that correspond with cell functioning, inflammation, and stress. A total of 87 women were enrolled in the study, half of whom had deep endometriosis, a quarter of whom also had the disease and sought surgical intervention, and a remaining quarter without reproductive concerns acted as a control. Twenty polychlorinated biphenyls (PCBs) and 30 organochlorine pesticide compounds were analyzed, as were various biomarkers and inflammatory cytokines. The analysis revealed two compounds to be positively associated with endometriosis – trans-nonachlor, a breakdown product of […]

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Joining Together to Give Thanks As We Confront the Challenges Ahead

Wednesday, November 24th, 2021

  (Beyond Pesticides, November 24, 2021) On Thanksgiving, thank you for being a part of Beyond Pesticides and sharing and contributing to the vision necessary to protect the web and fragility of life. We believe that there is no time like Thanksgiving to think about how we can more effectively join together as families and communities across divisions and different points of view to find a common purpose in protecting the health of the environment and all that inhabit it. Unfortunately, there are a host of pesticides, genetically engineered materials, and others in conventional Thanksgiving foods that not only impact human health, but threaten the environment. With far too many adverse health and ecological effects associated with toxic chemicals, organic practices are viable solutions to mitigate pesticide contamination and subsequent exposure. Read on as we consider the range of challenges we must confront, and the solutions that can bring us all together. The Climate As climate impacts grow, an increase in uses of synthetic pesticides in agriculture is likely — because of waning efficacy (pesticide resistance) of these compounds, and mounting pest pressure (i.e., increasing insect population and metabolism). Production of pesticides contributes to greenhouse gas emissions gas (e.g., nitrous […]

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EPA and Congress Must Act to Correct a Failed Pesticide Program

Monday, November 1st, 2021

(Beyond Pesticides, November 1, 2021) Join with 37 environmental and health groups, farm organizations, and beekeeper councils, who have delivered a letter to the Environmental Protection Agency (EPA) leaders seeking major reforms in the Office of Pesticide Programs (OPP). They provided a comprehensive list of OPP’s major failures as the lead federal office for pesticide regulation and management, including: Allowing chlorpyrifos to stay registered for more than 14 years after health experts and affected farmworkers petitioned for its removal based on its known neurological danger, Allowing unlimited use of Roundup (glyphosate) long after it was shown to contribute to deadly non-Hodgkin’s lymphoma in heavy users and it devastated the treasured monarch butterfly, now driven to near extinction in North America, Approving hundreds of neonicotinoid systemic insecticides, now the most widespread insecticide in the country where they are decimating honey and native bees and other key pollinators and beneficial species; and Registering dicamba in a highly volatile herbicide, a shocking blunder later overruled by a federal court ruling that stated OPP “not only substantially understated the risks …. It also entirely failed to acknowledge other risks, including those it was statutorily required to consider.” Take action: Tell EPA and Congress that the […]

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Groups Tell EPA’s Pesticide Program It’s a Failure, Call for Immediate Reforms

Tuesday, October 26th, 2021

(Beyond Pesticides, October 26, 2021) The Office of Pesticides Programs within the U.S. Environmental Protection Agency has become so captured by industry that it has lost sight of its health and environmental mission, according to a scathing critique issued today by 37 environmental, public health, and sustainable agriculture groups, including beekeeper councils. Led by Public Employees for Environmental Responsibility (PEER) and Beyond Pesticides, the groups are urging the Biden administration to adopt reforms within OPP to ensure pesticide approval and use decisions are science-based. EPA’s OPP has registered more than 18,000 separate pesticide products — far more than any other country — and more than 2 billion pounds of pesticides are sold annually in the U.S. They are used annually over roughly 250 million acres of farmland, across millions of acres of urban and suburban lands, and inside millions of homes, schools, and other buildings.  The coalition letter points to employee reports that managers within  OPP – Push through “Yes packages” of pesticide approvals greased by industry lobbying; Suppress toxicological and other concerns raised by professional staff; and Engage in outrageous waivers of vital toxicity study requirements, instead relying on “conditional” registrations to allow pesticide uses, despite missing key data. Seeing […]

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More Scientific Evidence that Endocrine-Disrupting Pesticides Disrupt Thyroid Function

Friday, September 10th, 2021

(Beyond Pesticides, September 10, 2021) Research conducted in Thailand shows that exposures to pesticides, even at low levels, can impact the human endocrine system and distort thyroid function. The study looked specifically at interactions of genetics and environment: it investigated associations between variations in genes involved in pesticide metabolism and altered thyroid hormone concentrations in agricultural workers. This research underscores some of the complexity and difficulty of determining human vulnerability to impacts of pesticide exposures, given genetic variables. Beyond Pesticides believes that this very complexity is a cogent argument for anchoring regulation of pesticides in the Precautionary Principle. If exposure to a pesticide can cause damage to human (or environmental) health, it sometimes will do so. Thus, to protect people’s health, agriculture and other land management practices must transition from the use of synthetic pesticides to broad adoption of organic regenerative approaches that obviate the need for such chemicals. This research is part of a longitudinal study that seeks to evaluate sub-chronic impacts, on thyroid hormone levels, of repeated exposures to a variety of pesticides. The farmworkers studied in this phase comprise two groups: those working on organically managed farms (216 subjects), and those working on conventional farms that use pesticides […]

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Endocrine (Hormone) Disrupting Chemicals, Including Pesticides, Also Affect the Nervous System

Thursday, September 9th, 2021

(Beyond Pesticides, September 9, 2021) A new study published in Toxicology Reports finds the same chemicals that disrupt the endocrine (hormone) system also disrupt the nervous system. Endocrine disruptors are xenobiotics (i.e., chemical substances like toxic pesticides foreign to an organism or ecosystem) present in nearly all organisms and ecosystems. The World Health Organization (WHO), European Union (EU), and endocrine disruptor expert (deceased) Theo Colborn, Ph.D., classify over 55 to 177 chemical compounds as endocrine disruptors, including various household products like detergents, disinfectants, plastics, and pesticides. Past research shows exposure to endocrine-disrupting pesticides adversely affects human health, from reproductive function to cancer development, and effects can span generations. However, this study is one of the few to evaluate associations between endocrine-disrupting chemicals and neurological function. Although the etiology (cause) of many sporadic (non-heritable) neurological diseases are unknown, scientists suggest exposure to environmental toxicants plays a role in disease development. Therefore, government and health officials have been urged to consider how exposure to endocrine-disrupting chemicals can impact bodily function and development apart from hormone disruption.   In the body, cells communicate through electrical or chemical signals transmitted within the nervous or endocrine system. Studies find exposure to endocrine-disrupting chemicals has a direct and indirect impact on hormone function and development. However, researchers investigated whether […]

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Study Finds Recently Banned, Common Insecticide Promotes Obesity Development, and Related Illnesses

Thursday, September 2nd, 2021

(Beyond Pesticides, September 2, 2021) A McMaster University (Canada) study demonstrates exposure to the recently banned, commonly used insecticide chlorpyrifos promotes obesity development, even at low doses. Obesity generally occurs following a caloric imbalance between food intake, absorption, and energy expenditure. Although various factors can promote obesity, researchers suggest environmental toxicants like chlorpyrifos play a role in obesity development through protein/enzyme suppression. According to the Center for Disease Control, 42 percent of the U.S. population is obese and at risk for type two diabetes, cardiovascular (heart) disease, stroke, several cancers, and other critical health issues. Therefore, research like this highlights the significance of investigating how toxic chemical exposure can impact health to prevent adverse disease outcomes. Researchers note, “These studies suggest that the effects of environmental toxicants on the development of obesity may have been underestimated as all studies to date have been conducted in mice housed at RT [room temperature]. Future studies examining the mechanisms driving reductions in β-AR [beta adrenergic receptors] signaling and whether there are associations between BAT [brown adipose tissue] metabolic activity and CPF [chlorpyrifos] in humans will be important.” Several environmental pollutants have links to obesity development via the effects on gut health, endocrine (hormone) and metabolic system, […]

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In Utero and Childhood Pesticide Exposure Increases Childhood Cancer Risk

Wednesday, September 1st, 2021

(Beyond Pesticides, September 1, 2021) A study published in Environmental Pollution finds the risk of acute childhood leukemia (AL) increases with prenatal and newborn exposure to pesticides (i.e., insecticides and herbicides). The study results support the hypothesis that chronic environmental pesticide exposure increases childhood leukemia risk up to two times. Maternal exposure has a stronger association with leukemia than childhood exposure. Insecticides and herbicides are of particular significance in increasing leukemia risk, especially for acute lymphoblastic leukemia. Although medical advancements in disease survival are more prominent nowadays, childhood AL remains the secondary cause of child mortality following physical injury. Furthermore, childhood leukemia survivors can suffer from chronic or long-term health complications that may be life-threatening. Although the etiology or cause of childhood AL involves the interaction of multiple components like lifestyle and genetics, emerging evidence indicates that environmental contaminants like pesticides (e.g., occupational exposures, air pollution, pesticides, solvents, diet, etc.) play a role in disease etiology. Pesticide contamination is widespread in all ecosystems, and chemical compounds can accumulate in human tissues resulting in chronic health effects. Children are particularly vulnerable to the impacts of pesticide exposure as their developing bodies cannot adequately combat exposure effects. Already, studies find low levels of pesticide exposure during […]

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Inspector General Rips EPA for Failure to Test Pesticides for Endocrine Disruption

Friday, August 20th, 2021

(Beyond Pesticides, August 20, 2021) The Office of the Inspector General (OIG) for the U.S. Environmental Protection Agency (EPA) has issued a damning report on the agency’s progress in protecting the population from potentially damaging endocrine disruption impacts of exposures to synthetic chemical pesticides (and other chemicals of concern). The report’s summary statement says, “Without the required testing and an effective system of internal controls, the EPA cannot make measurable progress toward complying with statutory requirements or safeguarding human health and the environment against risks from endocrine-disrupting chemicals.” This OIG report identifies and details the failings that Beyond Pesticides covered in an April 2021 Daily News Blog article, and many more — the net of which is that “we have yet to see EPA use endocrine disruption findings in pesticide registration decisions.” The OIG report chronicles a litany of failures. It finds that EPA’s Office of Chemical Safety and Pollution Prevention (OCSPP), which is responsible for testing all pesticide chemicals for endocrine disrupting activity in humans, has failed to do so. Specifically, it has not implemented a section of the Federal Food, Drug, and Cosmetic Act (FFDCA), as amended by the 1996 Food Quality Protection Act — the legislation that […]

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Tell EPA: It Must Ban Pesticides Unless Shown Not To Be Endocrine Disruptors

Monday, August 16th, 2021

(Beyond Pesticides, August 16, 2021) The failure of the U.S. Environmental Protection Agency (EPA) to meet its statutory responsibility to protect people and wildlife from the dire consequences of exposure to endocrine-disrupting chemicals must end. The Office of the Inspector General (OIG) for EPA has issued a damning report on the agency’s progress in protecting the population from potentially damaging endocrine disruption impacts of exposures to synthetic chemical pesticides (and other chemicals of concern) that shows the situation to be even worse than previously reported. The OIG’s summary statement says, “Without the required testing and an effective system of internal controls, the EPA cannot make measurable progress toward complying with statutory requirements or safeguarding human health and the environment against risks from endocrine-disrupting chemicals.” As a result, according to the OIG, “we have yet to see EPA use endocrine disruption findings in pesticide registration decisions.” Tell EPA that pesticide use cannot continue without findings of no endocrine disruption. Over recent decades, evidence has mounted showing that many pesticides interfere with hormones—and are therefore endocrine-disrupting chemicals (EDCs). In 1996, the promise of screening pesticides for endocrine disruption generated support from environmentalists and public health advocates for the Food Quality Protection Act […]

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296 Chemicals in Consumer Products Increase Breast Cancer Risk Through Hormone (Endocrine) Disruption

Wednesday, July 28th, 2021

(Beyond Pesticides, July 29, 2021) New research published in Environmental Health Perspectives finds nearly 300 different chemicals in pesticides, consumer products, and contaminated resources (i.e., food, water) increase breast cancer risks. Breast cancer is the most common cancer among women, causing the second most cancer-related deaths in the United States. Past studies suggest genetic inheritance factors influence breast cancer occurrence. However, genetic factors only play a minor role in breast cancer incidences, while exposure to external environmental factors (i.e., chemical exposure) may play a more notable role. There are grave concerns over exposure to endocrine (hormone) disrupting chemicals and pollutants that produce adverse health effects. Most types of breast cancers are hormonally responsive and thus dependent on the synthesis of either estrogen or progesterone. Hormones generated by the endocrine system greatly influence breast cancer incidents among humans. Several studies and reports, including U.S. Environmental Protection Agency (EPA) data, identify hundreds of chemicals as influential factors associated with breast cancer risk. Therefore, advocates point to the need for national policies to reassess hazards associated with disease development and diagnosis upon exposure to chemical pollutants. The study’s researchers note, “This study shows that a number of chemicals currently in use have the ability to manipulate hormones known to adversely […]

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Take Action: Tell EPA to Ban ALL Triazine Herbicides

Monday, June 28th, 2021

(Beyond Pesticides, June 28, 2021) The endocrine disrupting herbicide propazine (in the triazine family of frog-deforming endocrine disruptors) is set for cancellation by the U.S. Environmental Protection Agency (EPA). The move would eliminate use of the hazardous herbicide by the end of 2022. However, all pesticides in the triazine class, including atrazine and simazine, have similar properties and should be eliminated from use. Tell EPA to finish the job by banning all triazines. In November 2020, Beyond Pesticides and allied environmental groups launched a lawsuit against EPA for its intent to reregister the triazine family of chemicals. The agency’s interim approval of the herbicides, conducted under the Trump administration, eliminates important safeguards for children’s health and a monitoring programs intended to protect groundwater from contamination. As is typical with EPA, the agency merely proposed minor label changes in attempts to mitigate risks identified in its registration review. According to a release from EPA, it made the decision not out of concerns relating to human health and environmental protection, but in order to provide “regulatory certainty” for farmers and local officials. In March 2021, the Biden administration requested a stay on the atrazine lawsuit brought by environmental groups, as it indicated […]

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Propazine Cancelled by EPA—Advocates Urge Agency to Finish the Job by Banning Atrazine and Simazine

Tuesday, June 15th, 2021

(Beyond Pesticides, June 15, 2021) The endocrine disrupting herbicide propazine (in the triazine family of frog-deforming endocrine disruptors) is set for cancellation by the U.S. Environmental Protection Agency (EPA), according to a Federal Register notice published last week. The move would eliminate use of the hazardous herbicide by the end of 2022. While health and environmental advocates are pleased with the agency’s move, they say it is critical that all pesticides in the triazine class, including atrazine and simazine, also be eliminated from use. In November 2020, Beyond Pesticides and allied environmental groups launched a lawsuit against EPA for its intent to reregister the triazine family of chemicals. The agency’s interim approval of the herbicides, conducted under the Trump administration, eliminates important safeguards for children’s health and a monitoring programs intended to protect groundwater from contamination. As is typical with EPA, the agency merely proposed minor label changes in attempts to avert risks identified in its registration review. According to a release from EPA, it made the decision not out of concerns relating to human health and environmental protection, but in order to provide “regulatory certainty” for farmers and local officials. In March 2021, the Biden administration requested a stay […]

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Cutting Edge Science Must be Considered…See Science and Policy at the National Pesticide Forum 

Monday, June 14th, 2021

(Beyond Pesticides, June 14, 2021) Beyond Pesticides reports regularly on new science showing how pesticides harm human health and ecosystems. This science is not factored into EPA decisions. Tell EPA that cutting-edge science must be considered. More than 50 pesticide active ingredients have been identified as endocrine disruptors that mimic the action of a naturally-produced hormone, such as estrogen or testosterone, thereby setting off similar chemical reactions in the body; block hormone receptors in cells, thereby preventing the action of normal hormones; or affect the synthesis, transport, metabolism and excretion of hormones, thus altering the concentrations of natural hormones. Endocrine disruptors have been linked to attention deficit hyperactivity disorder (ADHD), Parkinson’s and Alzheimer’s diseases, diabetes, cardiovascular disease, obesity, early puberty, infertility and other reproductive disorders, childhood and adult cancers, and other metabolic disorders. Similar effects are found in other species. In spite of legal requirements and the flood of research, EPA issues Proposed Interim Decisions (PIDs) on pesticide registrations making no human health or environmental safety findings associated with the potential for endocrine disruption, or identifying additional data needs to satisfy Endocrine Disruptor Screening Program requirements in the PIDs. EPA cannot make findings of no unreasonable adverse effects without findings […]

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Exposure to Certain Pesticides Increase the Risk of Thyroid Cancer

Thursday, May 27th, 2021

(Beyond Pesticides, May 27, 2021) Research by the U.S. National Institutes of Health (NIH) finds exposure to lindane and metalaxyl pesticides heightens thyroid cancer risk. Both incidents of non-aggressive thyroid tumors and advanced-stage thyroid cancer are on the rise. However, researchers speculate that environmental pollutants, such as pesticides, may contribute to this increase, especially considering the pervasiveness of pesticide exposure among the general population. Globally, cancer is one of the leading causes of death, with over 8 million people succumbing to the disease every year. Notably, the International Agency for Cancer Research (IARC) predicts new cancer cases to rise 67.4% by 2030. Various environmental pollutants like pesticides have endocrine (hormone) disruption effects that promote higher instances of thyroid and reproductive cancers. Therefore, studies like these highlight the importance of understanding how pesticide use can increase the risk of latent diseases (e.g., cancers), which do not readily develop upon initial exposure. The researchers state, “More work is needed to understand the potential role of these chemicals in thyroid carcinogenesis.” The European Union and endocrine disruptor expert (deceased) Theo Colborn, Ph.D., classify more than 55 pesticide active ingredients as endocrine disruptors (EDs), including chemicals in household products like detergents, disinfectants, plastics, and pesticides. Endocrine disruptors are xenobiotics (i.e., toxic chemical substances foreign […]

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