(Beyond Pesticides, September 12, 2025) A team of Argentinian researchers conducted a study published in Environmental Toxicology and Pharmacology of the combined effects of the herbicide glyphosate and the pyrethroid insecticide cypermethrin. The researchers observed significantly higher apoptosis in cells exposed to the mixtures than to the individual pesticides—a synergistic response. Apoptosis, also known as programmed cell death, is a standard way that tissues handle damaged cells to remove threats to their function. The researchers sought to investigate the cellular toxicity of each chemical, individually and in combination, and assessed whether the effects of the mixture were additive or synergistic. Additive effects occur when two individual chemicals amplify the same sort of response, often because the chemicals have similar structures. Synergism can occur when chemicals have different mechanisms of action but work together to create more powerful effects. Mixtures of pesticides are the least-studied area of research conducted for regulatory purposes. While regulators provide instructions to applicators regarding which pesticides can be applied together and combined in tank mixtures, there is no control over how pesticides travel through the environment once applied, as they flow through the air as spray drift, lodge in soils and water, and are incorporated into […]

(Beyond Pesticides, August 21, 2025) The presence of Varroa mites in combination with the neonicotinoid insecticide imidacloprid increases the risk of bee mortality and disrupts the larval gut microbiome, according to a study of the synergy (a greater combined effect) between Varroa destructor, a parasitic mite that attacks and feeds on honey bees, and imidacloprid. The study in Pesticide Biochemistry and Physiology adds to the growing body of science on the severely declining bee population by investigating the toxic effects of both the parasites and pesticide stressors in honey bees (Apis mellifera). “Given that V. destructor may increase bees’ sensitivity to imidacloprid by compromising their physiological health and immunity, this study systematically assesses the effects of V. destructor infestation and imidacloprid exposure on honey bee survival, detoxification enzyme activity, and gut microbiota,” the authors explain. The intestinal tract and gut microbiome are crucial for digestion, metabolism, nutrient absorption, immune regulation, and pathogen defense. Within honey bees, the gut microbiome is “highly susceptible to external environmental stressors, such as pesticide exposure and parasitic infections [and] these disturbances can lead to microbial imbalances, ultimately affecting bee health.” (See studies here and here.) Previous research earlier this year, captured in Daily News Variability […]

(Beyond Pesticides, August 15, 2025) In analyzing the data present in an article in Data in Brief, concerning levels of pesticide biomarkers are present in the urine of adolescents and young adults that are linked to numerous health implications. The biomonitoring data, collected at two time points from participants in a longitudinal cohort study in the agricultural county of Pedro Moncayo, Ecuador, encompasses a total of 23 compounds used as herbicides, insecticides, and fungicides and their associated metabolites (breakdown products), which include organophosphates, pyrethroids, and neonicotinoids. The results highlight the disproportionate risks to a Latin American population that occur as a result of living in areas with heavy chemical-intensive agriculture. “This article presents urinary pesticide metabolite concentrations for 665 participants in the ‘Study of Secondary Exposure to Pesticides among Children, Adolescents, and Adults’ (ESPINA), which were collected during two follow-up assessments,” the authors describe. The first sampling period from July to October 2016, referred to as Follow-up Year [FUY]-8b, includes 529 of the participants, while the second sampling period from July to September 2022 (FUY-14a) includes 505 of the participants. All participants are within the agricultural community of Pedro Moncayo. As the authors note, “The ESPINA study aimed to include […]

(Beyond Pesticides, August 14, 2025) A review in Clinical and Experimental Obstetrics & Gynecology links various classes of environmental pollutants including pesticides and per- and polyfluoroalkyl substances (PFAS), both of which Beyond Pesticides has extensively covered, to adverse effects on the female reproductive system and common mechanisms of toxicity. These chemicals “disrupt the hypothalamic-pituitary-gonadal axis (HPG), impair ovarian function, and contribute to reproductive dysfunction through mechanisms such as oxidative stress, hormonal disruption, and epigenetic [gene expression or behavior] modifications,” the authors say. This leads to menstrual irregularities, infertility, and pregnancy complications, as well as increases in the risk of reproductive system disorders such as endometriosis, polycystic ovary syndrome (PCOS), and ovarian cancer, among others. “Additionally, transgenerational effects mediated by epigenetic modifications, germ cell damage, and placental transfer may adversely affect offspring health, increasing the risk of reproductive dysfunction, neurodevelopmental disorders, metabolic diseases, and cancer,” the researchers explain. This study, integrating recent epidemiological and experimental findings, provides an overview of major chemical classes that threaten women’s health and highlights the need for immediate action. As the authors point out, female reproductive health is important not only for those who choose to plan for a family but also for the overall well-being […]

(Beyond Pesticides, July 31, 2025) A study published in Environmental Advances finds that hundreds of honeybee hives across central and northern Italy are contaminated with various pesticides and their metabolites, including glyphosate and fosetyl.  “There was no significant difference in glyphosate presence between dead/dying and live bees, suggesting chronic exposure rather than acute toxicity. However, higher pesticide concentrations in dead/dying bees indicate potential sublethal effects contributing to colony distress,” according to the authors. This peer-reviewed study builds on the mounting evidence outlined in the literature connecting pesticide residues to nontarget harm to pollinators and other insects and animals that are critical to biodiversity. Background and Methodology “The primary objectives of this study were to develop and validate a reliable, sensitive method for analyzing polar pesticides [highly soluble in water] in honeybees and to investigate polar pesticides residue levels in honeybees across northern and central Italy,” say the researchers of this study, who conduct research at the Experimental Zooprophylactic Institute of Lombardy and Emilia Romagna “Bruno Ubertini”, Experimental Zooprophylactic Institute of Umbria and Marche “Togo Rosati”, and Experimental Zooprophylactic Institute of Lazio and Tuscany “M. Aleandri.” 314 honeybee samples were gathered voluntarily from local beekeepers in six regions of northern and […]

(Beyond Pesticides, July 17, 2025) The widespread use of pesticides year-after-year, decade-after-decade, has been found to lead to unintended consequences not only for public health but also for broader ecosystem stability and biodiversity. These impacts include potential nontarget harm through adverse developmental and reproductive effects on the vinegar fly, Drosophila melanogaster, the subject of a peer-reviewed study in Royal Society Open Science. The authors, who studied the organochlorine fungicide chlorothalonil, conclude, “Chlorothalonil exposure decreases larval survival, extends developmental duration and reduces fecundity.” “Even at the lowest tested concentration, chlorothalonil exposure resulted in reduced body weight, ovariole count and egg production compared with non-exposed individuals,” the researchers find. This study builds upon years of scientific research findings and critiques of existing federal pesticide law, as well as the U.S. Environmental Protection Agency’s (EPA) failure to fully assess the adverse impacts on biodiversity and ecosystem stability during the pesticide registration review process. Methodology and Background The goal of this study is to evaluate the health impacts on a nontarget insect species (Drosophila melanogaster) from chronic exposure to chlorothalonil. This specific fungicide was chosen for various reasons, including its wide use across cereals, vegetables, and fruits; evidence linked to adverse health effects on […]

(Beyond Pesticides, July 16, 2025) A study following a mass mortality event of approximately 200 monarch butterflies (Danaus plexippus plexippus) in Pacific Grove, California, highlights the role of pesticides, synthetic pyrethroids in particular, in causing lethal and sublethal effects to nontarget organisms. The research, published in Environmental Toxicology and Chemistry, detects residues of 15 pesticides and associated metabolites in the bodies of 10 deceased butterflies collected from the January 2024 event that occurred near an overwintering site frequented by monarchs. “On average, each monarch butterfly contained 7 pesticides,” the authors report. They continue, “Notably, three pyrethroid insecticides—bifenthrin, cypermethrin, and permethrin—were consistently detected at or near each chemical’s lethal dose (LD50).” LC50, or Lethal Concentration 50, values represent the concentrations of chemicals lethal to 50% of a test population. To assess pesticide residues within ten of the deceased butterflies, the researchers use liquid and gas chromatography with tandem mass spectrometry (LC-MS/MS and GC-MS/MS) and find “a total of 15 pesticides and associated metabolites in the butterflies, including 8 insecticides (plus 1 associated metabolite), 2 herbicides (plus 2 associated metabolites), and 2 fungicides.” The study “present[s] evidence that the mortality incident at the Pacific Grove Monarch overwintering site was likely caused by […]

(Beyond Pesticides, July 2, 2025) An article in The New Lede, entitled Seeking answers to a cancer crisis in Iowa, researchers question if agriculture is to blame, documents case studies of cancer diagnoses linked to chemical-intensive agriculture. Current national cancer rates, according to the American Cancer Society, show that two million new cancer cases are projected to occur during 2025 in the U.S. Additional research predicts 618,120 cancer deaths this year as well, highlighting a crisis of great concern. A wide body of science links increased cancer risks with exposure to agricultural chemicals, including petrochemical pesticides and synthetic fertilizers. Previous coverage from Beyond Pesticides showcases the disproportionate health risks to farmworkers and their families, as well as those living near agricultural fields, associated with exposure to harmful toxicants. Recent research ties pesticide use to cancer diagnoses among farmer populations through a literature review of clinical trials, as well as epidemiologic, case-control, and experimental studies, from not only the U.S. but Brazil, India, France, Egypt, Columbia, Ecuador, Mexico, Italy, and Spain. (See Daily News here.) Additional risks for children, as reported in a study in GeoHealth, are noted in Nebraska as exposure to agricultural mixtures show statistically significant positive associations with […]

(Beyond Pesticides, June 27, 2025) An article in The New York Times (NYT), entitled “A Killer Within Easy Reach,” highlights the use of the weed killer paraquat, a widely used herbicide in the U.S. and many other parts of the world despite being banned in over 70 countries, as the cause of numerous suicides. The article references the tiny nation of Suriname, located on the northeastern coast of South America, as they have “one of the highest suicide rates in the world,” with the majority of those deaths involving paraquat. Globally, paraquat is prevalently used in self-harm incidents. The chemical, when absorbed into the body, among other deadly effects, causes pulmonary fibrosis, making lung tissue brittle and causing respiratory failure. While this pesticide is intended and generally used for weed control, it is also highly lethal to humans in small amounts and is often easily accessible in many households. As the NYT article states, “Pesticides are among the leading means of suicide in agricultural areas of developing nations, implicated in more than 100,000 deaths annually.” Citing examples from around the world, the article states, “Sri Lanka’s crop yields had surged after the introduction of modern fertilizers and pesticides in the […]

(Beyond Pesticides, June 25, 2025) A United Kingdom (UK) study, published in May by the Women’s Environmental Network (Wen) and Pesticide Action Network (PAN) UK, is reporting levels of the herbicide glyphosate—a probable human carcinogen that is also linked to Parkinson’s disease—in tampons at concentrations 40 times higher than the legal drinking water limit. This finding highlights the serious public health threats that result from under-regulated period products, given that 1.8 billion people worldwide menstruate monthly, according to UNICEF.   The report raises fundamental concerns about the harm to women’s health associated with toxic chemical exposure. For tampon users, the vaginal route of exposure bypasses detoxification with a significantly higher absorption rate than skin. In addition, health concerns extend to ongoing chronic toxic chemical exposures to women worldwide working in cotton production and living in nearby communities. Methodology To investigate whether menstrual products contain harmful pesticide residues and whether current safety standards adequately control the risk of vaginal exposure, study researchers tested 15 boxes of tampons directly bought from UK supermarkets. These boxes were sent to an external laboratory for testing that looks for the presence of glyphosate and its breakdown product amionomethylphosphoric acid (AMPA) in the cotton material used to […]

(Beyond Pesticides, June 24, 2025) As changes in the executive branch of the federal government upend expectations among environmental stakeholders, the regulation of food safety in the United States is being revealed as a rickety structure built over a century with unpredictable and sometimes contradictory additions, extensions, remodels, and tear-downs. In the short term, clarity is unavailable, but there have been calls for revision and strengthening of regulatory processes—requiring lawmaker and regulator willingness to incorporate the vast body of evidence that pesticides do far more harm than good, and that organic regenerative agriculture is the surest path to human and ecological health. News reports out of Costa Rica in May brought public attention to drafted legislation to ban pesticides in the country that the World Health Organization (WHO) has defined as “extremely or highly hazardous, or those with evidence of causing cancer, genetic mutations, or affecting reproduction, according to the Globally Harmonized System (GHS).” The headline sparked a relook in this Daily News at the current and historical failure of U.S. policy, which allows cancer-causing pesticides in food production and land management, despite the booming success of a cost-effective and productive, certified organic sector for which petrochemical pesticides are not […]

(Beyond Pesticides, June 6, 2025) Published in Environmental Pollution, a study of commercial dry pet products finds dietary pesticide residues in dog and cat food, “highlighting the urgent need for improved regulatory frameworks to address the presence of non-approved pesticides in pet food.” Additionally, the researchers point out: “Current regulatory frameworks primarily assess the toxicity of individual pesticide compounds, yet real-world exposure involves complex mixtures that may lead to additive or synergistic effects. The presence of multiple residues in a single sample suggests that companion animals may be subjected to combined toxicological burdens that are not yet fully understood.” (See studies here, here, and here.) The researchers assess pesticide contamination, and their associated toxicological risks, in 83 total food products for dogs (43) and cats (40). Of the foods tested, the researchers found a total of 51 pesticides, many of which are banned in the European Union (EU), including 47% fungicides and 37% insecticides. “Pesticide residues in pet food pose potential risks to animal health, yet their occurrence and dietary exposure in companion animals remain largely unexplored,” the authors state. They continue: “To our knowledge, this is one of the first comprehensive investigations assessing both pesticide prevalence and potential dietary […]

(Beyond Pesticides, June 5, 2025) A study conducted in Pennsylvania and published in Environmental Entomology highlights threats to nontarget organisms from neonicotinoid insecticide exposure. Using species of ground beetles as an example, the study documents sublethal behavioral effects as well as decreased week-long survival. This research fills a notable gap in current research, with the authors explaining, “Predatory soil arthropods are under-represented in insecticide toxicity studies, severely limiting our understanding of how insecticides affect soil-invertebrate communities in agroecosystems.”   The researchers continue, “As a step toward addressing this issue, we conducted novel acute oral, topical, and soil-based toxicity assays on 9 ground beetle species (Coleoptera: Carabidae) in response to the neonicotinoid insecticides clothianidin, thiamethoxam, and imidacloprid.” The nine carabid beetle species, all common to agroecosystems in central Pennsylvania, were exposed to clothianidin, while additional assays with thiamethoxam and imidacloprid were conducted on the two most abundant species. A wide body of science exists that connects neonicotinoid exposure to health effects in a variety of nontarget organisms. Neonicotinoids, a class of neurotoxic insecticides, act as agonists of nicotinic acetylcholine receptors, “persist under field conditions, and are water soluble, enabling them to translocate into plants and provide systemic protection of seedlings,” the […]

(Beyond Pesticides, June 4, 2025) A new study published in Environmental Chemistry and Ecotoxicology finds that “higher pesticide exposure was significantly associated with elevated blood pressure and greater risks of hypertension.” More specifically, “[t]he results indicated that exposure to PNP [para-nitrophenol/parathion] and 2,4-D may contribute to an increased risk of hypertension.” According to data provided by the Centers for Disease Control and Prevention (CDC), roughly half of U.S. adults have hypertension, which can lead to increased risk for stroke and heart disease, two of the top causes of mortality in the nation. Amid worsening public health concerns, with young generations facing an increase in heart failure (see here for the Duke University School of Medicine analysis), advocates continue to call for the transformation of the food system, including increased access and production of whole-based organic food. Background Information and Methodology The authors of this community-based, case-control study are researchers at the Guangzhou Center for Disease Control and Prevention and the School of Public Health at Southern Medical University, both located in Guangzhou, China. The study included 360 participants, consisting of 180 hypertension cases and 180 non-cases (“normotensive individuals”) within China’s National Essential Public Health Services Program. All participants were over […]

(Beyond Pesticides, May 8, 2025) A study, published in Environmental Pollutants and Bioavailability, assesses the impacts on Nile tilapia (Oreochromis niloticus) with subacute and chronic exposure to thiamethoxam, a neonicotinoid insecticide, and finds genotoxicity, oxidative stress, and changes in tissue structure, among other threats to organ function and overall fish health. “The study focused on biochemical markers, genetic damage, pesticide residue levels in fish flesh, and histopathological changes in fish exposed to different concentrations of thiamethoxam,” the authors state. The threats do not end there; human health is also at risk from the consumption of these contaminated fish. “Unfortunately, neonicotinoids, rapidly washed into surface water from agricultural areas, pose a significant threat to environmental water quality and can harm non-target species, particularly aquatic organisms,” the researchers state. The accumulation of these chemicals leads to “ultimately harming both aquatic ecosystems and human health,” they say. In particular, the study highlights that prolonged exposure to high doses of thiamethoxam can cause “significant negative effects on fish health,” the authors note. They continue: “This exposure led to increased levels of urea and ALT [alanine aminotransferase] in the blood, indicating potential damage to the kidneys and liver. Additionally, thiamethoxam caused oxidative stress, as evidenced […]

(Beyond Pesticides, April 25, 2025) A novel study in Chemosphere finds impacts on male fertility in a bee species (Osmia bicornis) with exposure to sulfoxaflor, a systemic sulfoximine insecticide with similar mechanisms to neonicotinoids. “For the first time, we demonstrate that short-term chronic, field-realistic exposure to a common pesticide reduced pre-copulatory display (36%) and sounds (27%) [courtship behaviors], increased the number of copulations (+110%) and the mating duration (+166%), while finally reducing sperm quantity (25%) and mating success (43%),” the researchers report. They continue, “Our research raises considerable concern on the impact of field-realistic, low sublethal pesticide levels on the fertility and reproductive success of pollinators.” Mating behaviors and the ability to successfully reproduce determines the survival of species. As the authors state: “Mating disorders may therefore contribute to the recent decline in insect and pollinators’ health worldwide. While the impact of pesticides on pollinators is widely considered as a driving factor for reducing pollinators’ health, their effect on mating behaviour and male fertility remains widely overlooked.” The red mason bee (O. bicornis) can “provide essential pollination service for both crops and wild plants sustaining food production and biodiversity while serving as a bioindicator of environmental health.” The abundance and […]

(Beyond Pesticides, April 23, 2025) Recent reviews of scientific literature, in both Chemosphere and Reports in Public Health, associate Parkinson’s disease (PD), the second most prevalent neurodegenerative disease globally, with pesticide exposure. “Given the pervasive nature of pesticide residues in everyday food consumption and inadequate monitoring of their long-term toxicological impacts, the role of pesticide exposure as a modifiable risk factor for neurological disorders, including PD, warrants urgent attention,” the researchers state in the article in Chemosphere. In describing the history of Parkinson’s and previous research, the authors in Reports in Public Health note that while PD etiology is not fully understood, it is a multifactorial disease. “Hereditary factors are present in approximately 10% of diagnosed cases of Parkinson’s disease, presenting early onset; while the other 90% of cases are categorized as idiopathic or sporadic Parkinson’s disease, occurring in older individuals and may be associated with exposure to environmental agents,” the researchers say. This disease, first described by English physician James Parkinson, M.D. in 1817, involves neurochemical changes that present as “the appearance of cardinal motor symptoms, such as bradykinesia, rigidity, postural instability, and rest tremor, which are essential for the clinical diagnosis of the disease,” the researchers note. The […]

(Beyond Pesticides, April 16, 2025) Documented for the first time, 15 currently used pesticides (CUPs) and four metabolites (breakdown or transformation products—TP) were found in the marine atmosphere over the Atlantic Ocean. Three legacy (banned) pesticides were also discovered. According to a recent study published in Environmental Pollution, researchers found empirical evidence for pesticide drift over remarkably long distances to remote environments. The findings of this study build on existing research that pollution knows no borders or boundaries, emphasizing Beyond Pesticides’ mission to advocate for the value of the precautionary principle through the elimination of synthetic chemicals and replacement with organic systems that address the root causes of pest pressures–including systemic failure to feed soil microbial life.   Background and Methodology “In this study, 329 pesticides, including 282 CUPs and 36 transformation products, were [sampled for] in the atmosphere across a south-north transect on the Atlantic Ocean,” said the authors. They unpack the three main objectives to address the focus and major objectives of their research: “[T]he determination of pesticide concentrations in the atmosphere of the Atlantic Ocean, The investigation of the spatial distribution of pesticides across the Atlantic Ocean, and The elucidation of potential sources and factors influencing pesticide transport […]

(Beyond Pesticides, April 15, 2025) A study in Communications Earth & Environment, through field, greenhouse, and laboratory experiments involving three plant bug species, finds both species-specific and sex-specific sensitivity responses to neonicotinoid insecticide exposure—highlighting the threats to grassland insect communities that are disregarded in risk assessments. By assessing the effects of Mospilan®SG, with the active ingredient acetamiprid, the researchers determine that nontarget plant bug species are highly sensitive to neonicotinoids and face community-level harm with exposure. As systemic insecticides, neonicotinoids move through the vascular system of plants, expressing the poison through pollen, nectar, and guttation droplets. As persistent pesticides, these chemicals indiscriminately poison insects and organisms in the soil. “Although pesticides have been proposed as one of the main causes of insect decline, there are still few studies assessing their effects on non-target species under field conditions,” the authors state. They continue: “In this study, we address the existing research gap on insecticide exposure of non-target herbivorous insects, focusing on two main aspects: (1) realistic exposure scenarios, (2) community-level effects, i.e., differential sensitivity between closely related species and between sexes of the same species. We chose plant bugs (Heteroptera: Miridae) as a model group because they are one of the […]

(Beyond Pesticides, April 8, 2025) A comprehensive literature review in Environment & Health analyzes evidence from human biomonitoring, epidemiological studies, and toxicological studies that link adverse effects on women’s reproductive health, specifically impacting the ovary, to pesticide exposure. In examining the scientific literature, consisting of over 200 studies performed in the last 25 years, the authors find pesticide exposure threatens women’s health through ovarian dysfunction. “Epidemiological studies have shown that pesticide exposures are associated with early/delayed menarche [first occurrence of menstruation], menstrual cycle disorders, early menopause, long time to pregnancy, polycystic ovary syndrome, primary ovarian insufficiency, infertility, and implantation failure in women,” the researchers state. They continue, “Both in vivo [in animals] and in vitro [in cells] studies have shown that exposure to pesticides disrupts the estrous cycle, reduces the follicle pool, alters hormone levels, and impairs oocyte [egg] maturation.” These reproductive implications are noted with many different classes of pesticides, such as insecticides, including organochlorine pesticides (OCPs), organophosphates (OPs), pyrethroids, and neonicotinoids, as well as herbicides and fungicides. The authors, however, comment on present research gaps: “Much of the available epidemiological evidence focuses on legacy insecticides, such as OCPs, and a subset of insecticides that are still in use […]

(Beyond Pesticides, March 28, 2025) The Rhine Valley in southwestern Germany is renowned for the agricultural bounty it has provided for centuries. Today, the area is home to dense wine, vegetable, fruit, and cereal cultivation. However, a study shows that current regulation of pesticides, even in the relatively progressive European Union, is inadequate to protect humans and all the other organisms that produce the environment necessary for human life and civilization.  The study goal was to determine how far—and which—pesticides traveled beyond the croplands of vegetables, fruit orchards, and cereals, as well forested lands, into nontarget areas that should serve as refugia for plants, animals, and invertebrates not considered pests. Based at the Landau Institute for Environmental Sciences at the University of Kaiserslautern-Landau, the researchers used innovative methods to measure the types, concentrations, and distribution of pesticides. They took samples from three landscape categories—vegetation, topsoil, and surface water—at 78 sites distributed along six transects, each reaching from the valley floor to the tops of the mountains on either side. Samples were taken from grasses, shrub leaves, and topsoils along each transect, together with water samples from rivers, small streams, ponds, and puddles. They tested for 93 current-use pesticides (CUPs). There […]

(Beyond Pesticides, March 27, 2025) In Ecotoxicology, results of a study on Nile tilapia (Oreochromis niloticus) exposed to florpyrauxifen-benzyl (FPX) suggest the new herbicide causes oxidative stress (imbalances affecting the body’s detoxification abilities that lead to cell and tissue damage), with specific genotoxic (damage to genetic material) and hepatotoxic (damage to the liver) effects on nontarget species. The authors state: “According to the available literature, no data exist on the toxicity of FPX in fish. Therefore, this study aims to investigate, for the first time, the potential toxicity and associated mechanistic effects of the pyridine-carboxylic acid herbicide (FPX) on the non-target species, Nile tilapia.” According to the Wisconsin Department of Natural Resources, “Florpyrauxifen-benzyl is a systemic herbicide (i.e., it moves throughout the plant tissue). It is a WSSA Group 4 herbicide, meaning that the mechanism of action is by mimicking the plant growth hormone auxin and causing excessive elongation of plant cells, ultimately killing the plant.” The researchers, from Menoufia University, the Agricultural Research Center, and Cairo University in Egypt, focus on FPX as it is the active ingredient in Divixton 2.5% EC, a newly released herbicide used in rice fields and applied directly to freshwater aquatic bodies for emergent […]

(Beyond Pesticides, February 27, 2025) In analyzing current scientific literature and data on glyphosate-based herbicides (GBHs), a research article in Environmental Sciences Europe finds that glyphosate (GLY) persists in bones before reentering the bloodstream. The mechanisms in which GLY interacts with important cells for development, called hematopoietic stem cells (HSCs), and breaks and rearranges DNA offer a possible explanation for the heightened risk of cancer, specifically blood cancers like non-Hodgkin lymphoma (NHL), myeloma, and leukemia. “Existing data on GLY/GBH metabolism and genotoxicity provide critical insights into how exposures may be contributing to blood cancers,” according to the study’s author, Charles Benbrook, PhD. Dr. Benbrook continues: “A significant portion of GLY reaching blood moves quickly into bone marrow and then bone, where it can bioaccumulate and persist… Data reviewed herein suggest that a portion of the GLY excreted by most people on a daily basis can be traced to the shedding of calcium-GLY complexes in bone back into the blood supply.” This allows for near-constant contact between glyphosate molecules and hematopoietic stem cells, which are immature cells that can develop into any type of blood cell. Mutations in hematopoietic stem cells can cause blood cancers to emerge. Those at disproportionate risk […]