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Daily News Blog

30
Jun

Study Associates Exposure to Pesticide Mixtures with an Increase in Alzheimer’s Disease Prevalence

(Beyond Pesticides, June 30, 2026) A peer-reviewed article, published in Scientific Reports, focuses on the link between exposure to pesticide mixtures and Alzheimer’s Disease (AD) prevalence at the county-level across the United States. Alzheimer’s, a type of dementia that affects memory, thinking, and behavior, accounts for 60-80% of dementia cases. In conducting a novel cross-sectional analysis of data on pesticide application intensity and disease prevalence, the researchers, from the Medical University of South Carolina, are able to identify exposure clusters with significant associations to the occurrence of AD. The strongest positive associations, where AD prevalence increases as pesticide exposure increases, are “observed for a soil fumigation/nematicide system, an herbicide-dominant vegetation control regime, and a neuroactive insecticide system,” the authors note. These findings link pesticide mixtures to increased AD rates. (See the full PDF of the study here.) Study Importance and Background AD is a condition that gradually damages and destroys neurons in the brain, with disproportionate risks across the U.S. in certain geographical areas. (See here and here.) “These spatial patterns suggest that contextual and environmental determinants may contribute to disparities in dementia burden beyond established individual-level risk factors,” the researchers state. They continue, “Although AD dementia is the leading […]

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19
Apr

Research Links Parkinson’s and Lewy Body Disease with Chemical Effects on Brain and Gut

(Beyond Pesticides, April 19, 2024) Parkinson’s disease (PD) and certain forms of dementia have been associated with exposure to pesticides, industrial chemicals, and air pollution for decades. But the mechanisms of disease progression have been unclear, and U.S. regulators have been reluctant to recognize the risks. Now neurologist E. Ray Dorsey, MD of the University of Rochester and researchers from the University of Alabama at Birmingham and Aarhus University in Denmark propose a new research paradigm based on tracking how toxicants cause neurodegeneration through inhalation and ingestion pathways. The paradigm, the authors believe, can be used to gain insight into how PD and a form of dementia known as Lewy body disease (LBD) are initiated as many as 50 years before the onset of symptoms. Dorsey and colleagues build on a recent theory that PD and LBD may be two versions of the same basic disease, both involving Lewy bodies in the nervous system. The group’s proposal was published in the Journal of Parkinson’s Disease in April. If its recommended research agenda produces the anticipated empirical support, the new paradigm will demand integration of many interdisciplinary lines of evidence showing that environmental exposures to synthetic chemicals may be the primary cause […]

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