(Beyond Pesticides, April 2, 2025) In examining prenatal residential proximity of documented pesticide spraying in California to the menstrual cycle characteristics of 273 Latina adolescents, researchers report in the American Journal of Epidemiology a positive association between exposure to the insecticide methomyl and heavy bleeding. Other pesticides appear to influence menstrual symptoms as well. “Adolescents’ menstrual cycle characteristics can be ‘vital signs’ of health and impact quality of life,” the authors share. They continue, “To our knowledge, this is the first study to examine the association between prenatal pesticide exposure and menstrual outcomes in adolescents of any demographic group.” Menstrual cycle characteristics, such as dysmenorrhea (painful or uncomfortable menstrual cramps), irregularity, and heavy menstrual bleeding, can also be indicators of underlying health conditions, including endometriosis, polycystic ovary syndrome (PCOS), thyroid dysfunction, and bleeding disorders. By associating the pesticide exposure of mothers during pregnancy to impacts on their children, the researchers highlight important health risks for women and young girls that are often disregarded. “The prenatal period is a critical period of reproductive development that may be particularly sensitive to endocrine disruption,” the researchers share. As previously reported by Beyond Pesticides, endocrine-disrupting chemicals are any synthetic or natural compounds that hinder […]

(Beyond Pesticides, March 7, 2025) In honor of International Women’s Day on Saturday, March 8, 2025, Beyond Pesticides sheds light on the disproportionate risks to women from toxic chemicals that are often unaccounted for and even dismissed throughout pesticide regulatory review and the underlying statutes. In a roundup of Daily News coverage in 2024, as well as the most recent scientific studies in 2025, on the scientific links between pesticide exposure and adverse effects in women, this article highlights the growing inequities in pesticide threats to women’s health.  Women farmers and farmworkers are particularly excluded when assessing pesticide risks. As previously reported by Beyond Pesticides, a study published in Occupational and Environmental Medicine finds that pesticide exposure, especially during puberty, can play a role in ovarian cancer development among female farmers. Although there are many studies that evaluate the risk for cancers among farmers, very few scientific articles cover the risk of ovarian cancer from pesticide exposure.  Additionally, this study suggests the role of hormones in ovarian cancer prognosis and development, highlighting an association with endocrine disruption. Endocrine disruption can lead to numerous health problems in multiple organ systems, including hormone-related cancer development (e.g., thyroid, breast, ovarian, prostate, testicular), reproductive […]

(Beyond Pesticides, March 4, 2025) A study in GeoHealth of pediatric cancers in Nebraska links exposure to agricultural mixtures with the occurrence of these diseases. The authors find statistically significant positive associations between pesticide usage rates and children with cancer, specifically brain and central nervous system (CNS) cancers and leukemia. “Our study is the first to estimate the effect of an agrichemical mixture on the pediatric cancer rate in Nebraska,” the study authors share. “One significant advantage of our study is that we identified the pesticide consistently applied over 22 years in Nebraska counties and then estimated the overall mixture effect of these pesticides on pediatric cancer.” The elevated effect of pesticide mixtures, a reality that is not evaluated in the U.S. Environmental Protection Agency’s (EPA) pesticide registration program, was reported in Oecologia (2008), documenting harm to amphibian populations even if the concentration of the individual chemicals is within limits considered acceptable. (See additional coverage here.) There is a wide body of science highlighting the disproportionate risk of adverse health effects in children with pesticide exposure. Their small size and developing organ systems, propensity to crawl and play near the ground, tendency for frequent hand-to-mouth motion, and greater intake of […]

(Beyond Pesticides, February 27, 2025) In analyzing current scientific literature and data on glyphosate-based herbicides (GBHs), a research article in Environmental Sciences Europe finds that glyphosate (GLY) persists in bones before reentering the bloodstream. The mechanisms in which GLY interacts with important cells for development, called hematopoietic stem cells (HSCs), and breaks and rearranges DNA offer a possible explanation for the heightened risk of cancer, specifically blood cancers like non-Hodgkin lymphoma (NHL), myeloma, and leukemia. “Existing data on GLY/GBH metabolism and genotoxicity provide critical insights into how exposures may be contributing to blood cancers,” according to the study’s author, Charles Benbrook, PhD. Dr. Benbrook continues: “A significant portion of GLY reaching blood moves quickly into bone marrow and then bone, where it can bioaccumulate and persist… Data reviewed herein suggest that a portion of the GLY excreted by most people on a daily basis can be traced to the shedding of calcium-GLY complexes in bone back into the blood supply.” This allows for near-constant contact between glyphosate molecules and hematopoietic stem cells, which are immature cells that can develop into any type of blood cell. Mutations in hematopoietic stem cells can cause blood cancers to emerge. Those at disproportionate risk […]

(Beyond Pesticides, January 31, 2025) A recent cross-sectional study in Heliyon highlights the link between sleep disorders in Thai farmers and pesticide exposure. The authors find pesticide exposure as an important risk factor for sleep disorders after surveying 27,334 farmers over the age of 20 who had work experience for at least five years. The importance of sleep health is reflected both physically and mentally, as studies find “sleep deficiency increase[s] mortality and various health complications, including hypertension, obesity and type 2 diabetes, cardiovascular diseases, mood disorders, and neurodegenerative disorder.” Additional studies find that these issues are compounded when sleep health is affected by environmental factors such as pesticide exposure. (See previous Beyond Pesticides’ coverage here and here.) The researchers report: “The study found a positive association of 19 individual pesticides (twelve insecticides, two herbicides, and five fungicides). Some associations demonstrated a dose-response pattern. Additionally, the study revealed that women are at a higher risk of sleep-related issues with pesticide exposure compared to males. These results not only substantiate existing literature but also unveil several new individual pesticides that may impact sleep health.” Focusing on study participants in Thailand, which is “characterized by heavy pesticide use and minimal protective measures, […]

(Beyond Pesticides, January 9, 2025) In a Frontiers in Public Health review article, researchers report on the wide body of science connecting adverse effects to female reproductive system, such as infertility, with exposure to endocrine-disrupting chemicals (EDCs). The authors call these effects a significant concern for public health, as there has been growing evidence of EDCs with risk factors for decreased fertility.   Infertility “affects a substantial proportion of the world’s population with approximately one in six people affected,” the researchers note. They continue: “Over the last 70 years, global fertility has been constantly in decline due to behavioral and societal changes… [E]merging evidence has shown that infertility incidence is linked to exposure to environmental factors such as tobacco, alcohol, and a wide range of endocrine-disrupting chemicals (EDCs) including pesticides (chlorpyrifos, glyphosate, dichlorodiphenyltrichloroethane [DDT] and methoxychlor), phthalates, polychlorinated biphenyls (PCB), dioxins, and bisphenols.”  In this review, over 100 studies are summarized to showcase the link between EDC exposure and reproductive effects in women, including infertility and related diseases such as endometriosis, premature ovarian insufficiency (POI), and endocrine axis dysregulation. The studies included investigating the “mechanisms by which EDCs cause ovarian aging, folliculogenesis, decrease of oocyte quality, ovulation disorders, development and receptivity […]

(Beyond Pesticides, December 16, 2024) The fact that three-quarters of all U.S. fruits and nuts and one-third of all U.S. vegetables are grown in California means that all U.S. food eaters have a stake in how food is grown there. California is proposing the continued use of the fumigant 1,3-dichloropropene (1,3-D, also known as Telone), which can cause deadly effects to farmworkers and endocrine disrupting effects to communities of people exposed through nontarget chemical drift from farmland. So, it is with deep concern that Beyond Pesticides is urging the state of California, where the chemical is undergoing review, to ban the toxicant. Endocrine disruption, an adverse effect for which the U.S. Environmental Protection Agency (EPA) has never completed a pesticide testing protocol, adversely affects the functioning of glands and hormones and is linked to major life-threatening diseases in most organ systems in the body—contributing to attention deficit hyperactivity disorder (ADHD), Parkinson’s, Alzheimer’s, diabetes, cardiovascular disease, obesity, early puberty, infertility and other reproductive disorders, and childhood and adult cancers. In a recently released draft regulation, the California Department of Pesticide Regulation (CDPR) will allow highly elevated exposure to 1,3-D, ignoring the scientific literature and advice of the state’s own toxicologists at […]

(Beyond Pesticides, December 12, 2024) A literature review of 161 articles in Discover Toxicology finds that pesticides with different mechanisms of action cause memory and learning impairments. These effects are noted in nontarget species including humans. Pesticide “[e]xposure during development, as well as chronic environmental and occupational exposure, can contribute to decreased cognitive performance,” the researchers say. With a focus on organophosphate pesticides, synthetic pyrethroids, and neonicotinoid insecticides, the authors highlight neurological impacts. Both learning and memory are crucial for the survival of many species. “Considering the importance of learning and memory for human and non-human animal behavior and the growing association between pesticide exposure and cognitive impairment, the aim of this review was to describe the studies showing the impact of pesticide exposure on memory and learning abilities in nontarget species, providing evidence of the impact of pesticides in central nervous system function,” the researchers state. The 161 articles included in the review were identified through database searches in PubMed/Medline and Scielo. The authors note, “Inclusion criteria for article selection included all articles published in English between 2015 and 2024 containing original studies in animals or humans with single or multiple pesticides exposure.” The articles consist of 132 preclinical […]

(Beyond Pesticides, November 26, 2024) A study in Environment International finds that young children who exhibit higher levels of pesticide metabolites in their urine show more pronounced neurobehavioral problems at the age of ten. Researchers in China document how exposure during early childhood, especially during the sensitive window before the age of two, is linked to hyperactivity/inattention problems such as attention deficit hyperactivity disorder (ADHD). While adding to the body of science connecting pesticide exposure to learning and developmental disorders, this study offers a “novel perspective on characterizing the fluctuation in repeated measurements of multiple environmental chemicals and identifying the potential critical windows,” the authors share. (See previous Daily News coverage here, here, and here.) The researchers analyze data from questionnaires and urine samples through the ongoing Sheyang Mini Birth Cohort Study (SMBCS), which is a long-term prospective cohort study that associates environmental chemical exposure during pregnancy and childhood to negative health effects. This data addresses combined pesticide exposures in young children with neurobehavior analyses at the age of ten to determine any correlation. Within the SMBCS, a total of 1303 pregnant women are enrolled. When the children reached ages one, two, three, six, seven, eight, nine, and ten years […]

(Beyond Pesticides, November 8-11, 2024) On Veterans Day 2024 we honor those who have served the country and allies. In the 117th (2021-2022) U.S. Congress, legislators enacted The Sergeant First Class Heath Robinson Honoring Our Promise to Address Comprehensive Toxics Act of 2022 (PACT Act). Since the law passed just over two years ago, there has been just under 1.3 million total approved claims marking a roughly 75% approval rate for PACT Act related claims, according to Department of Veteran Affairs (VA) accounting of progress between August 10, 2022, and October 12, 2024 through its dedicated bimonthly VA PACT Act Performance Dashboard. The legacy of toxic burn pits (open air areas where the military has burned toxic waste) and other avenues for toxic exposure in military bases oversees, as well as within the United States in Hawai’i (See coverage on asbestos exposure continuously impacting veterans, as reported on by Honolulu Civil Beat) and Puerto Rico (See peer-reviewed literature review here on toxic heavy metals in International Journal of Environmental Research and Public Health), among other areas, comes at a time when the country assesses the ongoing impacts of a history that has been characterized by critics as colonial or imperialist. […]

(Beyond Pesticides, October 15, 2024) In Environmental Epidemiology, researchers from Columbia University and the University of Southern California, along with representatives from the nonprofit Comite Civico del Valle in Brawley, California, report the heightened risk of wheezing for five- to twelve-year-olds in the rural communities of California’s Imperial Valley. Through a school-based survey, the authors find associations between living near pesticide applications and more wheeze symptoms among the children. According to the authors, residents of the Imperial Valley, which is located near the border between the United States (U.S.) and Mexico, “are primarily Latino, 1 in 3 children live in poverty, and there is a 20% unemployment rate. The county faces poor air quality and excess particulate matter levels. Further, one in five children is diagnosed with asthma and the rate of asthma-related pediatric emergency room visits and hospitalizations is two times the CA state average.” This highlights the disproportionate risk for residents in this area regarding environmental exposure to harmful chemicals. Children are already more susceptible to health complications following pesticide exposure, as they take in greater amounts of toxic chemicals relative to their body weight and have still-developing organ systems. Young children in environments with higher levels of […]

(Beyond Pesticides, September 24, 2024) Recent commentary in Frontiers in Toxicology by two researchers, Maricel Maffini, PhD and Laura Vandenberg, PhD, highlights the pitfalls in the current regulatory systems in the United States (U.S.) for chemicals that threaten human health. Despite many advancements in science over the past few decades, and the wealth of studies that tie chemical exposure to negative health effects, risk assessments, and subsequent risk management, remain “static” and “outdated,” according to the authors. “There is increasing concern amongst public health professionals, environmental health scientists, and medical organizations about exposures to synthetic chemicals,” the researchers say. “These organizations’ concerns are based on the overwhelming evidence showing associations between chemical exposures and adverse health outcomes in human populations.” Such concerns have sparked a debate on current regulatory methods for chemicals that are present in highly used products, such as pesticides, plastic containers, and food.    The authors continue, “There are now thousands of studies showing associations between these chemicals and adverse health effects in humans including neurological disorders and learning disabilities, metabolic outcomes, infertility, thyroid dysfunction, and cancers.” Additional health effects can be seen in the Pesticide-Induced Diseases Database. Of the many harmful chemicals, per- and polyfluoroalkyl substances […]

(Beyond Pesticides, August 21, 2024) A literature review, published this month in the Journal of Agricultural and Food Chemistry, explores levels of pesticide residues found in samples of human urine with environmental exposure and dietary intake and confirms prior findings about the benefits of an organic diet. Similar to past findings, lower concentrations of chemicals are detected in the urine of participants who report eating an organic diet. By analyzing 72 scientific research studies published between 2001 to 2023, the review assesses routes of exposure and “explores urinary concentrations and detection frequency of metabolites of organophosphates and pyrethroids, as well as herbicides such as 2,4-D and glyphosate,” the authors say. While “exposure to pesticide residues is influenced by a variety of demographic factors, including occupation, agricultural practices, seasonal variations, residence, diet, age, and gender,” the authors say, the concentrations of pesticides and their metabolites in human urine highlights the disproportionate risk to certain groups as well as the overall threat to the health of humans and the environment. Pesticide exposure can occur from dermal/skin contact or inhalation, through residence or work, and with dietary intake. “Pesticides in urine can be detected as parent compounds, specific metabolites corresponding to a specific […]

(Beyond Pesticides, July 2, 2024) Men’s Mental Health Awareness Month, which took place last month, evokes concern about the growing body of science linking pesticide exposure to neurological effects linked to depression. Recent studies reveal elevated rates of psychiatric disorders, including suicide, among farmers, with problems more common for males.  Through systematic reviews, meta-analyses, surveys and interviews, and blood sampling, these three studies add to the growing body of science linking pesticide exposure to neurological impacts. First, in the Journal of Agromedicine, researchers from Greece and the United Kingdom review eight studies and find a significant positive association between pesticide poisoning and depression in agricultural populations.1 Second, a study in Toxicology shows a link between depression in Brazilian farmers and pesticide exposure, most notably with glyphosate usage.2 Third, the latest study in Environmental Toxicology and Pharmacology focuses on work by researchers from Spain in identifying farmers exposed to chlorpyrifos, mancozeb, and malathion that have higher rates of depressive symptoms and suicide attempts.3  Through a meta-analysis of published research, the authors of the Agromedicine journal article identify pesticide poisoning as a risk factor of depression. With depression affecting more than 264 million individuals worldwide, this is a field of interest with […]

Calls for Holistic Environmental Justice and a Shift Away from Societal Dependence on Petrochemical Pesticides and Fertilizers (Beyond Pesticides, June 18-19, 2024) Juneteenth (June 19) commemorates the date in 1865 when the enslavement of Black Americans ended in the westernmost Confederate state of Texas, over two and a half years after the Emancipation Proclamation of 1863 and the defeat of the Confederacy on April 9, 1865. On June 19, 1865, Union Major General Gordon Granger brought federal troops to Galveston, Texas and finally, and belatedly, implemented the Emancipation Proclamation, which proclaimed on January 1, 1863 freedom from slavery across the nation. Carl Mack, PhD, a historian and former President of the Seattle-King County NAACP, reminds us that there were still 225,000 enslaved Black Americans in Kentucky and Delaware after June 19, 1865 and the end of the Civil War until December 6, 1865 when Georgia became the 27th state to ratify the 13th amendment. “That is the day in which Georgia ratified the 13th amendment,” Dr. Mack goes on to discuss the remaining three former border states on their progress in adopting the 13th amendment. “As it applies to Delaware and Kentucky, Delaware did not ratify the 13th amendment until […]

(Beyond Pesticides, April 9, 2024) The United States Court of Appeals for the Fifth Circuit, in an opinion authored by Circuit Judge Cory T. Wilson, has vacated an action by the U.S. Environmental Protection  Agency (EPA) that had ordered the Texas-based manufacturer Inhance Technologies, L.L.C. to stop producing plastic containers that leach toxic per- and polyfluoroalkyl substances (PFAS) into pesticides, household cleaners, condiments, and additional products. EPA has taken action after the agency determined that the PFAS created during the fluorination process “are highly toxic and present unreasonable risks that cannot be prevented other than through prohibition of manufacture.” While the court is not challenging EPA’s authority to determine the hazards associated with PFAS exposure to be unacceptable, on a technicality, it is finding that the agency used the wrong section of the Toxic Substances Control Act (TSCA), Section 5, which the court says is focused on new uses. According to the Court, “The EPA is just not allowed to skirt the framework set by Congress by arbitrarily deeming Inhance’s decades-old fluorination process a “significant new use,” even though EPA’s awareness of the PFAS contamination was “new” to the agency and not disclosed by the manufacturer. Even if EPA were […]

(Beyond Pesticides, February 28, 2024) The U.S. Environmental Protection Agency (EPA) is putting on hold its Vulnerable Species Project (VSP) after vociferous comments from the petrochemical pesticide industry to instead, “create a narrow, tailored policy rather than a sweeping, burdensome one,” according to a recent op-ed in the Wall Street Journal. Upon heavy pushback from the petrochemical pesticide industry and agribusiness, EPA is hosting a variety of workshops and openings for the public to provide feedback not just on VSP, but the Endangered Species Act (ESA) Workplan the Biden Administration originally introduced in 2021 in its entirety. Advocates are calling for the strengthening of pesticide regulation given the impending decisions that may shape the fate of ESA-FIFRA (Federal Insecticide, Fungicide, and Rodenticide Act) compliance for years to come. As EPA continues through its pesticide registration program to advance continued dependency on pesticides through its interpretation of FIFRA, despite the availability of nontoxic alternatives, endangered species extinction and biodiversity collapse has never been a high priority. While EPA has initiated efforts to address a significant backlog of pesticide evaluations, Civil Eats has reported that the agency faces a task so extensive that it may require several additional decades to fully catch up. EPA officials stated, “Even if EPA completed […]

(Beyond Pesticides, January 16, 2024) The U.S. Environmental Protection Agency (EPA) has long been criticized for its failure to evaluate the effectiveness (or efficacy) of all the pesticides it registers. A petition, for which there is now an open public comment period (submit comments by January 22, 2024), challenges what advocates call a basic failure of the agency to evaluate the claimed benefits of pesticides. Because of this long-standing situation, those who purchase pesticides do not know that the pesticides they buy will meet expectations for control. For farmers, that means that EPA has not evaluated whether the pesticide’s use actually increases productivity of the treated crops and/or whether over time the target pest (weed, insect, fungus) will become resistant. For consumers, it also means that there is not an independent analysis of whether the pesticide products work. As EPA implements the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), not only is there no agency assessment of whether the pesticide’s use will achieve its intended purpose, there is not a determination as to whether there is a less toxic way of achieving the pest management goal. As Beyond Pesticides cited last year, a piece published in the Proceedings of the […]

(Beyond Pesticides, October 19, 2023) The second session of the 40th National Forum, Forging a Future with Nature, will focus on environmental justice and offer a unique conversation with the United Nations Rapporteur on Toxics and Human Rights and an environmental justice history professional. Both celebrated speakers have studied and written about the long-standing social, economic, and health problems related to pesticides and disproportionate harm to people of color. The Forum will take place at 2:00 pm EDT on Tuesday, October 24, 2023. (See free registration information HERE.)   Beyond Pesticides brings together this Forum session with the inspiration of the words of Dr. Martin Luther King, Jr., who wrote in Letter from a Birmingham Jail (1963), “Injustice anywhere is a threat to justice everywhere. We are caught in an inescapable network of mutuality, tied in a single garment of destiny. Whatever affects one directly, affects all indirectly.” Sixty years later, people of color—in the U.S. and around the world—still struggle with those same inequities that impose disproportionate risks interwoven in the fabric of economic and social systems in the United States and worldwide. The Forum takes place in the context of widespread toxic chemical exposure throughout communities and all strata […]

(Beyond Pesticides, September 22, 2023) Beyond Pesticides today announced the second session of the National Forum, Forging a Future with Nature: The existential challenge to end petrochemical pesticide and fertilizer use, scheduled for October 24, 2:00pm EDT. The hard-hitting talks of Dave Goulson, PhD, and André Leu, DSc. are now available as recordings on the Beyond Pesticides website.  Beyond Pesticides introduces the Forum: A future supported by the natural environment depends on our effective involvement in decisions in our homes, communities, states, and at the federal level to ensure that we are taking the steps necessary to protect against existential threats to health, biodiversity, and climate. The Forum is an important opportunity to hear from those working as scientists, advocates, land managers (from gardens, parks, play fields to farms), and public decisionmakers about steps being taken and action needed to prevent catastrophic collapse of the natural systems that sustain life. A key part of this conversation, according to Beyond Pesticides, is addressing inequities associated with elevated rates of poisoning, contamination, and diseases in people of color communities. In introducing the importance of environmental justice and addressing the disproportionate risk from toxic pollution to people of color communities as a key […]

(Beyond Pesticides, September 6, 2023) In late August, the Office of the Inspector General (OIG) at the U.S. Environmental Protection Agency (EPA) released a report concluding that EPA “took a siloed approach” to the cumulative impacts of chemical exposures and the disproportionate nature of those exposures. This approach keeps different parts of the EPA from coordinating their efforts and hinders understanding of the breadth and depth of chemical exposures. OIG reached this disturbing finding despite the issuance of several executive orders by President Biden requiring EPA to develop policies and actions to assess cumulative impacts of chemical exposures across departments, laws, and environmental media (air, water, bodies, food etc.) and to pay more attention to environmental justice. Beyond Pesticides has stressed that the whole constellation of chemical exposures and effects should be considered when governments set public policies and regulations. Just last March, Daily News covered another OIG report castigating EPA for betraying its mission by failing to address the fact that very high levels of per- and polyfluoroalkyl compounds known as “forever chemicals” have been found in some common pesticides. OIG also berated EPA for succumbing to Donald Trump’s interference with setting toxicity values for the “forever chemical” perfluorobutane […]