25
Jun
(Beyond Pesticides, June 25, 2025) A United Kingdom (UK) study, published in May by the Womenâs Environmental Network (Wen) and Pesticide Action Network (PAN) UK, is reporting levels of the herbicide glyphosateâa probable human carcinogen that is also linked to Parkinsonâs diseaseâin tampons at concentrations 40 times higher than the legal drinking water limit. This finding highlights the serious public health threats that result from under-regulated period products, given that 1.8 billion people worldwide menstruate monthly, according to UNICEF.  The report raises fundamental concerns about the harm to womenâs health associated with toxic chemical exposure. For tampon users, the vaginal route of exposure bypasses detoxification with a significantly higher absorption rate than skin. In addition, health concerns extend to ongoing chronic toxic chemical exposures to women worldwide working in cotton production and living in nearby communities. Methodology To investigate whether menstrual products contain harmful pesticide residues and whether current safety standards adequately control the risk of vaginal exposure, study researchers tested 15 boxes of tampons directly bought from UK supermarkets. These boxes were sent to an external laboratory for testing that looks for the presence of glyphosate and its breakdown product amionomethylphosphoric acid (AMPA) in the cotton material used to […]
Posted in aminomethylphosphonic acid (AMPA), endometriosis, Glyphosate, Herbicides, Reproductive Health, Uncategorized | 1 Comment »
24
Jun
(Beyond Pesticides, June 24, 2025) As changes in the executive branch of the federal government upend expectations among environmental stakeholders, the regulation of food safety in the United States is being revealed as a rickety structure built over a century with unpredictable and sometimes contradictory additions, extensions, remodels, and tear-downs. In the short term, clarity is unavailable, but there have been calls for revision and strengthening of regulatory processesârequiring lawmaker and regulator willingness to incorporate the vast body of evidence that pesticides do far more harm than good, and that organic regenerative agriculture is the surest path to human and ecological health. News reports out of Costa Rica in May brought public attention to drafted legislation to ban pesticides in the country that the World Health Organization (WHO) has defined as âextremely or highly hazardous, or those with evidence of causing cancer, genetic mutations, or affecting reproduction, according to the Globally Harmonized System (GHS).â The headline sparked a relook in this Daily News at the current and historical failure of U.S. policy, which allows cancer-causing pesticides in food production and land management, despite the booming success of a cost-effective and productive, certified organic sector for which petrochemical pesticides are not […]
Posted in Agriculture, Alternatives/Organics, and Rodenticide Act (FIFRA), Breast Cancer, Cancer, Endocrine Disruption, Environmental Protection Agency (EPA), Immunotoxicity, multi-generational effects, non-Hodgkin's Lymphoma, Pesticide Mixtures, Pesticide Regulation, synergistic effects, Uncategorized, World Health Organization | No Comments »
13
Jun
(Beyond Pesticides, June 13, 2025) A report highlights the ongoing stress to the Chesapeake Bay Watershed from pollutants, particularly pesticides. The Chesapeake Bay is the largest estuary in the contiguous United States, with tributaries shared among six states and the District of Columbia. It receives runoff from nine major river systems traversing a wide mix of land uses, with significant agricultural and urban areas nearest the Bay and forest along the western boundary. Nearly 13 million people get their drinking water from the watershed. The watershed report by the Maryland Pesticide Education Network focuses primarily on the herbicide atrazine, the neonicotinoid insecticide thiamethoxam, and per- and polyfluorinated compounds (PFAS). Atrazine needs little introduction, being notorious for disrupting hormones, particularly estrogen, as demonstrated by the pioneering work of Tyrone Hayes and more recent research analyzed by Beyond Pesticides here, here and here. In male fish, it can trigger production of egg proteins, especially vitellogenin, and development of eggs in their testicles. These are manifestations of intersex, in which an organism shows forms of sexual differentiation of both sexes. The Chesapeake watershed report notes that atrazine and metolachlor (also an estrogen/androgen disruptor and suspected human carcinogen) occur together frequently in the Chesapeake […]
Posted in Atrazine, Cancer, Deleware, Endocrine Disruption, Environmental Protection Agency (EPA), Maryland, neonicotinoids, New York, Pennsylvania, PFAS, Uncategorized, Virginia, Washington D.C., West Virginia | 2 Comments »
17
Apr
(Beyond Pesticides, April 17, 2025) A literature review in Reproductive Sciences finds glyphosate (GLY) and glyphosate-based herbicides (GBH) impact womenâs reproductive health, adding to the long list of documented harm from this widely used weed killer. The authors note, âConsidering the widespread use of GLY, the controversy regarding its endocrine-disrupting potential and reproductive toxicity, and the innumerable lawsuits filed against Bayer and Monsanto by consumers for morbidities related to Roundup™ exposure, the purpose of this review is to summarize the current literature on the potential adverse effects of GLY and GBHs on the female reproductive tract and discuss possible clinical implications on reproductive health outcomes, including polycystic ovarian syndrome (PCOS), endometriosis, and female fertility.â Glyphosate and aminomethylphosphonic acid (AMPA), the primary metabolite (breakdown product) of GLY, are found throughout the environment in soil and water, as well as in samples of blood, urine, seminal plasma, and breast milk. Studies have detected residues in farmworkers, as well as “in the urine of 60â80% of the general public in the USA, including pregnant women and children.â (See studies here, here, and here.) The ubiquitous use of GLY and GBH, and subsequent persistence, threatens the health and well-being of all. Previous studies have […]
Posted in Agriculture, aminomethylphosphonic acid (AMPA), Bayer, DNA Damage, Endocrine Disruption, endometriosis, Glyphosate, Herbicides, Infertility, Monsanto, Oxidative Stress, Reproductive Health, Women's Health | No Comments »
02
Apr
(Beyond Pesticides, April 2, 2025) In examining prenatal residential proximity of documented pesticide spraying in California to the menstrual cycle characteristics of 273 Latina adolescents, researchers report in the American Journal of Epidemiology a positive association between exposure to the insecticide methomyl and heavy bleeding. Other pesticides appear to influence menstrual symptoms as well. âAdolescentsâ menstrual cycle characteristics can be âvital signsâ of health and impact quality of life,â the authors share. They continue, âTo our knowledge, this is the first study to examine the association between prenatal pesticide exposure and menstrual outcomes in adolescents of any demographic group.â Menstrual cycle characteristics, such as dysmenorrhea (painful or uncomfortable menstrual cramps), irregularity, and heavy menstrual bleeding, can also be indicators of underlying health conditions, including endometriosis, polycystic ovary syndrome (PCOS), thyroid dysfunction, and bleeding disorders. By associating the pesticide exposure of mothers during pregnancy to impacts on their children, the researchers highlight important health risks for women and young girls that are often disregarded. âThe prenatal period is a critical period of reproductive development that may be particularly sensitive to endocrine disruption,â the researchers share. As previously reported by Beyond Pesticides, endocrine-disrupting chemicals are any synthetic or natural compounds that hinder […]
Posted in Acephate, California, Children, Chlorpyrifos, Diazinon, Dimethoate, Endocrine Disruption, endometriosis, Environmental Protection Agency (EPA), Glyphosate, Imidacloprid, Malathion, mancozeb, Maneb, Methomyl, Oxidative Stress, Permethrin, Reproductive Health, Women's Health | No Comments »
25
Mar
(Beyond Pesticides, March 25, 2025) An editorial in Expert Review of Cardiovascular Therapy finds that triazole fungicides pose a significant risk of cardiotoxicity with âgrowing concerns regarding their safety for human health, especially in long-term exposure,â the authors share. After analyzing the known mechanisms of cardiotoxicity of triazole pesticides in mammals, they conclude that âthe most effective approach to mitigating triazole-induced cardiotoxicity lies in prevention.â Triazoles, a class of fungicides, target fungi by inhibiting the biosynthesis of ergosterol, an essential component of their cell membranes. As the researchers share, âCompounds such as tebuconazole, propiconazole, and difenoconazole are among the most used triazoles in agriculture.â Triazoles are utilized as antifungal medications, despite the rise of resistant infections, in addition to their use as systemic pesticides on many fruit and vegetable crops, including grapes, wheat, corn, and soybeans.  As Beyond Pesticidesâ previous coverage indicates, many triazole fungicides in the U.S. are registered for use despite evidence of endocrine disruption established over a decade ago in a U.S. Geological Survey report. These pesticides exhibit common mechanisms of toxicity often disregarded in U.S. Environmental Protection Agency (EPA) risk assessments, with a multitude of studies showcasing the myriads of health threats that the agency does […]
Posted in Cardiovascular Disease, difenoconazole, Endocrine Disruption, Fungicides, Oxidative Stress, Propiconazole, tebuconazole | No Comments »
11
Mar
(Beyond Pesticides, March 11, 2025) A study in Toxics analyzes ipconazole, a triazole fungicide often used as a coating on treated seeds and as a foliar treatment on the leaves of plants. âTriazole pesticides are widely used throughout the world, but their abuse causes toxic effects in non-targeted organisms,â the researchers state. In the current study, unintended reproductive effects are noted in male sheep (ram) and pigs (also known as porcine or swine). This research focuses on the impact of ipconazole exposure on spermatozoa (sperm) in two mammal species and finds spermiotoxicity through significantly reduced sperm viability, as well as alterations in enzyme and gene expression related to fertility. âTo our knowledge, this is the first study to evaluate the cytotoxic effect of the triazole ipconazole on mammalian spermatozoa,â the authors share. This analysis utilizes semen samples from the Reproductive Biotechnology Laboratory of the Major National University of San Marcos in Lima, Peru, the university where six of the nine researchers are Faculty of Veterinary Medicine.  âThe sperm were exposed to ipconazole concentrations of 1, 5, 10, 50 and 100 ÂľM, and to a control without ipconazole,â they say. Similar concentrations have been used in previous cytotoxicity studies with ipconazole. […]
Posted in difenoconazole, Endocrine Disruption, Epigenetic, Infertility, Ipconazole, Livestock, men's health, Oxidative Stress, Peru, Reproductive Health, tebuconazole | No Comments »
10
Mar
(Beyond Pesticides, March 10, 2025) Following International Womenâs Day, celebrated on March 8, 2025, the poignant findings on women, gender, and hazardous substances in a United Nations report raise critical issues of concern and cause for urgent action to phase out petrochemicals. The Report of the Special Rapporteur on the implications for human rights of the environmentally sound management and disposal of hazardous substances and wastes, by Marcos Orellana, was delivered to the 79th Session of the United Nations General Assembly in July 2024. Excerpts from the report follow: âWomen make up roughly 60 to 70 per cent of the agricultural labour force in developing countries where pesticides and pesticide handling are especially poorly regulated. In Zambia, for example, two thirds of the labour force is engaged in agriculture, and 78 per cent are women farmers and peasants. Women there play a significant role in pesticide application, often without any or adequate personal protective equipment, especially during activities such as weeding, harvesting, and washing pesticide-laden clothes.â âIn higher-income countries, women who do agricultural work are often poor and/or migrants; pesticides are one of many dimensions of marginalization and damage to their well-being. The European agriculture sector uses many seasonal and […]
Posted in Agriculture, Alternatives/Organics, Breast Cancer, Cancer, Endocrine Disruption, Environmental Justice, Environmental Protection Agency (EPA), Farmworkers, Take Action, Uncategorized | No Comments »
07
Mar
(Beyond Pesticides, March 7, 2025) In honor of International Womenâs Day on Saturday, March 8, 2025, Beyond Pesticides sheds light on the disproportionate risks to women from toxic chemicals that are often unaccounted for and even dismissed throughout pesticide regulatory review and the underlying statutes. In a roundup of Daily News coverage in 2024, as well as the most recent scientific studies in 2025, on the scientific links between pesticide exposure and adverse effects in women, this article highlights the growing inequities in pesticide threats to womenâs health. Women farmers and farmworkers are particularly excluded when assessing pesticide risks. As previously reported by Beyond Pesticides, a study published in Occupational and Environmental Medicine finds that pesticide exposure, especially during puberty, can play a role in ovarian cancer development among female farmers. Although there are many studies that evaluate the risk for cancers among farmers, very few scientific articles cover the risk of ovarian cancer from pesticide exposure. Additionally, this study suggests the role of hormones in ovarian cancer prognosis and development, highlighting an association with endocrine disruption. Endocrine disruption can lead to numerous health problems in multiple organ systems, including hormone-related cancer development (e.g., thyroid, breast, ovarian, prostate, testicular), reproductive […]
Posted in Breast Cancer, Cancer, Endocrine Disruption, Farmworkers, Holidays, Occupational Health, Reproductive Health, Women's Health | 1 Comment »
23
Jan
(Beyond Pesticides, January 23, 2025) According to reporting by Bangor Daily News, âStarting in 2025, the Miâkmaq Nation, [Upland Grassroots], [University of Virginia], the Connecticut Agricultural Experiment Station and Central Aroostook Soil and Water Conservation District will use a four-year, $1.6 million EPA grant to continue hemp planting at [the former] Loring [Air Force Base] and testing potential ways to extract PFAS [per- and polyfluoroalkyl substances] from harvested hemp.â This grant will support an existing initiative led by members of the Miâkmaq Nation to remediate this contaminated Superfund-designated land purchased from the U.S. government in 2009 based on interviews of the Nationâs Vice Chief Richard Silliboy. Â PFAS, colloquially known as âforever chemicals,â persist in various petrochemical-based pesticides, chemicals, and other consumer products. Beyond Pesticides, in coordination with national coalitions and local communities, continues to act against the proliferation of PFAS and PFAS-contaminated products through grassroots organizing and litigation. The use and associated public and environmental exposure to PFAS as pesticide active ingredients in pesticide products and a wide range of consumer products (including containers holding pesticides targeting mosquitoes and sewage sludge fertilizers) represent a grave threat as a result of their use in homes, emergency rooms, health care facilities, […]
Posted in Biosolids/Sewage Sludge, Indigenous People, Maine, PFAS, Sewage Sludge, soil health, State/Local, Uncategorized | No Comments »
16
Jan
(Beyond Pesticides, January 16, 2025) In Ecotoxicology and Environmental Safety, researchers highlight a multitude of studies on endocrine disrupting chemicals (EDCs) and endocrine disrupting pesticides (EDPs) showing epigenetic effects from exposure. These EDCs imitate the action of endocrine hormones and lead to gene damage and multigenerational adverse effects to health. âThese chemicals can interfere with the normal functioning of target tissues by altering their response to hormonal signals, thereby affecting various physiological processes including reproduction, development, the nervous system, the immune system, and even the process of carcinogenesis [causing cancer],â according to the authors from Hebei Agricultural University and Chinese Academy of Agricultural Sciences. Â In causing epigenetic modifications, the authors describe that EDCs can create changes âat the nuclear and mitochondrial DNA (nDNA and mtDNA) or RNA levels, without changing the underlying DNA sequence. These alterations modify the structure or conformation of DNA, influencing gene expression and, consequently, cellular function.â They continue, âThe mechanisms of epigenetics include changes in DNA methylation, chromatin modifications and the involvement of certain noncoding RNAs.â In reviewing over 80 studies on EDCs, predominantly fluorinated compounds such as per- and polyfluoroalkyl substances (PFAS), the researchers provide a summary of linkages between pesticide exposure and the […]
Posted in Body Burden, Cyfluthrin, DDT, Endocrine Disruption, Endosulfan, Epigenetic, Fipronil, Glyphosate, hexachlorobenzene (HCB), Imidacloprid, Metolachlor, PFAS, Sulfoxaflor, Trifluralin | No Comments »
09
Jan
(Beyond Pesticides, January 9, 2025) In a Frontiers in Public Health review article, researchers report on the wide body of science connecting adverse effects to female reproductive system, such as infertility, with exposure to endocrine-disrupting chemicals (EDCs). The authors call these effects a significant concern for public health, as there has been growing evidence of EDCs with risk factors for decreased fertility.  Infertility âaffects a substantial proportion of the worldâs population with approximately one in six people affected,â the researchers note. They continue: âOver the last 70 years, global fertility has been constantly in decline due to behavioral and societal changes… [E]merging evidence has shown that infertility incidence is linked to exposure to environmental factors such as tobacco, alcohol, and a wide range of endocrine-disrupting chemicals (EDCs) including pesticides (chlorpyrifos, glyphosate, dichlorodiphenyltrichloroethane [DDT] and methoxychlor), phthalates, polychlorinated biphenyls (PCB), dioxins, and bisphenols.â In this review, over 100 studies are summarized to showcase the link between EDC exposure and reproductive effects in women, including infertility and related diseases such as endometriosis, premature ovarian insufficiency (POI), and endocrine axis dysregulation. The studies included investigating the âmechanisms by which EDCs cause ovarian aging, folliculogenesis, decrease of oocyte quality, ovulation disorders, development and receptivity […]
Posted in Atrazine, Children, Chlorpyrifos, DDT, endometriosis, Endosulfan, Glyphosate, Infertility, Reproductive Health, Women's Health | No Comments »
17
Dec
(Beyond Pesticides, December 17, 2024) A systematic review of studies on pesticides as endocrine-disrupting chemicals (EDCs) on body weight, published in Biomedicines, evaluates 36 clinical and preclinical studies and links their agricultural use to obesity. The authors, with the lead researchers from the School of Medicine and Health Sciences at Catholic University of Valencia San Vincente, Valencia, Spain, assess studies on a range of pesticides, including organophosphates, pyrethroids, neonicotinoids, and others. In addition to concluding that the EDCs promote obesity, they report that the chemicals cause âother anthropometric changes by altering lipid and glucose metabolism, modifying genes, or altering hormone levels such as leptin.â Endocrine disruption and obesity are public health concerns, and there is a wide body of science linking pesticide exposure to these effects (see more here). âObesity is considered to be a worldwide pandemic that leads to an increase in medical costs and thus becomes a public health problem,â the researchers share. They continue, â[Obesity] is also associated with the increased production of environmental chemicals, also called environmental obesogens, used mainly in agriculture, as disease vector control, helping to prevent harmful effects caused by fungi, bacteria, or even pests, using pesticides, insecticides, and herbicides, or endocrine disruptors […]
Posted in 2,4-D, acetamiprid, Benomyl, Bifenthrin, Carbamates, Carbendazim, Chlorpyrifos, Clothianidin, cypermethrin, Dicamba, Diuron, Endocrine Disruption, Fenoxycarb, Fipronil, Fungicides, Glyphosate, Imidacloprid, Isoxafutole, Malathion, mancozeb, Maneb, neonicotinoids, Obesity, organophosphate, Permethrin, Synthetic Pyrethroid, Thiamethoxam | No Comments »
16
Dec
(Beyond Pesticides, December 16, 2024) The fact that three-quarters of all U.S. fruits and nuts and one-third of all U.S. vegetables are grown in California means that all U.S. food eaters have a stake in how food is grown there. California is proposing the continued use of the fumigant 1,3-dichloropropene (1,3-D, also known as Telone), which can cause deadly effects to farmworkers and endocrine disrupting effects to communities of people exposed through nontarget chemical drift from farmland. So, it is with deep concern that Beyond Pesticides is urging the state of California, where the chemical is undergoing review, to ban the toxicant. Endocrine disruption, an adverse effect for which the U.S. Environmental Protection Agency (EPA) has never completed a pesticide testing protocol, adversely affects the functioning of glands and hormones and is linked to major life-threatening diseases in most organ systems in the bodyâcontributing to attention deficit hyperactivity disorder (ADHD), Parkinsonâs, Alzheimerâs, diabetes, cardiovascular disease, obesity, early puberty, infertility and other reproductive disorders, and childhood and adult cancers. In a recently released draft regulation, the California Department of Pesticide Regulation (CDPR) will allow highly elevated exposure to 1,3-D, ignoring the scientific literature and advice of the stateâs own toxicologists at […]
Posted in 1, 3-dichloropropene, 1-3D, ADHD, Agriculture, Alzheimers's, Cancer, Diabetes, Endocrine Disruption, Obesity, Parkinson's, Telone, Uncategorized | 3 Comments »
13
Dec
(Beyond Pesticides, December 13, 2024) In October, the U.S. Environmental Protection Agency (EPA) approved the registration applications of BASF Corporation and Mitsui Chemicals Crop & Life Solutions, Inc. for the use of different formulations of the L-isomer of glufosinate (also known as âL-glufosinateâ and âglufosinate-Pâ) as new active herbicidal ingredients. This decision marks one of the first times that EPA has employed its new Herbicide  Strategy Framework to determine the level of mitigation necessary to protect listed species and critical habitat under the Endangered Species Act (ESA). Glufosinate is an organophosphate, with known neurotoxic, reproductive/developmental effects, toxic to aquatic life, and mobile in soils (see Beyond Pesticides Gateway). Scientists have found that formulated glufosinate is generally more toxic to aquatic and terrestrial animals than the technical grade active ingredient. Manufacturers are introducing newer glufosinate products as alternatives for glyphosate-based herbicides, like Bayer/Monsantoâs âRoundupâ and dicamba. The Center for Biological Diversity notes in comments submitted to EPA on this decision, âL-glufosinate has the potential to be used on tens of millions acres of land every year given the crops EPA has proposed to register it on. The scale of potential use is far above most new active ingredients.â This first significant application […]
Posted in Agriculture, BASF, Chemical Mixtures, Chemicals, Endangered Species Act (ESA), Environmental Protection Agency (EPA), glufosinate, Herbicides, Lawns/Landscapes, Pesticide Regulation, Uncategorized, Wildlife/Endangered Sp. | No Comments »
13
Nov
(Beyond Pesticides, November 13, 2024) A study in Chemosphere, conducted by researchers from the Institute of Biochemistry and Molecular Biology in Germany, reveals the varied lethal and sublethal effects of different glyphosate mixtures through tests on the South African clawed frog, Xenopus laevis (X. laevis). After exposing embryos to four glyphosate formulations, mortality, morphological defects, altered heartbeat rate, and impaired heart-specific gene expression are observed. Glyphosate, an herbicide and popular weed killer in many RoundupÂŽ products, is one of the most commonly detected pesticides in waterbodies worldwide, threatening aquatic organisms and overall biodiversity. This study investigates the effects of Glyphosat TF, Durano TF, Helosate 450 TF, and Kyleo, four formulations containing glyphosate, as compared to the effects of pure glyphosate on embryonic development in amphibians. The formulations consist of varying concentrations of the active ingredient glyphosate, as well as other active and inert ingredients. The authors share that, âGlyphosat TF contains 34% glyphosate and 10â20% d-glucopyranose, while Durano contains 39â44% glyphosate and 1â5% NâN-dimethyl-C12-C14-(even numbered)-alkyl-1-amines. In Helosate most of the ingredients are listed – 50â70% glyphosate, 1â10% isopropylamine, 1â3% lauryl dimethyl betaine, 0.25â1% dodecyl dimethylamine. Kyleo only lists the active ingredients glyphosate (27.9%) and 2,4-D (32%).â 2-cell stage embryos (early […]
Posted in 2,4-D, Aquatic Organisms, Biodiversity, Chemical Mixtures, Death, Developmental Disorders, DNA Damage, Endocrine Disruption, Environmental Protection Agency (EPA), Epigenetic, Glyphosate, Herbicides, Pesticide Mixtures, synergistic effects | No Comments »
04
Nov
(Beyond Pesticides, November 4, 2024) The U.S. Environmental Protection Agency (EPA) last week opened a public comment period on the regulation of endocrine-disrupting pesticides, a proposal that lays out a drawn-out 10-year process that is narrow in evaluating the underlying mechanism that causes endocrine disruption. The proposal, published in the Federal Register as a partial settlement agreement and consent decree, responds to a lawsuit filed by farmworker and health groups challenging the agency’s failure to test and regulate endocrine-disrupting pesticides. Earlier in the year, after over 25 years of delay following the 1996 Congressional mandate to determine whether pesticides disrupt the endocrine system of humans and other organisms, EPA issued a proposal for modifying its approach to the implementation of the Endocrine Disruptor Screening Program (EDSP). The National Institutes of Environmental Health Sciences explains endocrine disruptors this way: âEndocrine-disrupting chemicals (EDCs) are natural or human-made chemicals that may mimic, block, or interfere with the bodyâs hormones, which are part of the endocrine system. These chemicals are associated with a wide array of health issues. . . Endocrine glands, distributed throughout the body, produce the hormones that act as signaling molecules after release into the circulatory system. The human body is […]
Posted in Alternatives/Organics, Chemicals, Endocrine Disruption, Environmental Protection Agency (EPA), Litigation, Pesticide Regulation, Take Action, Uncategorized | No Comments »
08
Oct
(Beyond Pesticides, October 8, 2024) A comprehensive literature review in Endocrines, published in September, amasses hundreds of studies on endocrine-disrupting chemicals (EDCs) that showcase adverse effects on growth, development, reproduction, and metabolism. The authors, a team of scientists and academics from Brazil, shed light on the link between EDC use and thyroid dysfunction, leading to increasingly prevalent illnesses and deadly diseases. Â Â Â EDCs are any synthetic or natural compounds that hinder endocrine system functions and create harmful effects on organisms. These chemicals can impact the thyroid gland, which is vital in producing hormones and plays a role in several body functions. As the researchers state, âSeveral EDCs have been classified as thyroid disruptors, impairing thyroid hormone [TH] production, synthesis, metabolism, transport, and/or actions. Notably, thyroid disorders are the second most prevalent endocrine disease worldwide, with incidence increasing significantly in recent years.â The authors continue, â[S]tudies have correlated this rise in thyroid dysfunctions and cancers with increased exposure to EDCs. Although many EDCs are linked to thyroid dysfunction, this review focuses on the deleterious effects of plasticizers, organochlorine pesticides, and per- and poly-fluoroalkyl substances on thyroid function. These contaminants are commonly found in food, water, and everyday products.â This review helps […]
Posted in Atrazine, Birth defects, Cancer, carbamate, Carbamates, Children, Chlorpyrifos, DDT, Dieldrin, Endocrine Disruption, Endosulfan, Fipronil, mancozeb, organochlorines, organophosphate, Permethrin, PFAS, phthalates, Propiconazole, pyrethroids, Synthetic Pyrethroid, Thyroid Disease, Women's Health | No Comments »
14
Aug
(Beyond Pesticides, August 14, 2024) Pesticide exposure is linked to negative birth outcomes in a recent study in the American Journal of Epidemiology. This study adds to that body of science, but is novel research since, âEpidemiological studies of pesticide exposures and stillbirth in the United States have not been published in the past two decades, a time period that has seen dramatic changes in pesticide use compared to the 20th century,â the authors state. The study analyzes Arizona pesticide use records and birth certificates from 2006-2020. Researchers correlate mothers living within 500 meters of any pyrethroid, organophosphate (OP), or carbamate insecticide applications during specific windows before and during pregnancy with stillbirth. The authors focus on exposure during the prenatal period, as it is a susceptible time frame in which any contact with pesticides can negatively impact health. Numerous studies report several adverse birth and childhood outcomes with prenatal exposure. To link pesticide exposure and negative birth outcomes, Arizona records that encompass 1,237,750 births, 2,290 stillbirths, and 27 pesticides were analyzed. The authors âevaluate associations of pyrethroids, OPs, and carbamate insecticides with stillbirth by using data from the Arizona Pregnant womenâs Environment and Reproductive outcomes Study (Az-PEARS), a project that […]
Posted in Acephate, Arizona, carbamate, Carbaryl, Cyfluthrin, cypermethrin, dacthal, Dimethoate, Malathion, organophosphate, Permethrin, pyrethroids, Reproductive Health, Women's Health | No Comments »
08
Aug
(Beyond Pesticides, August 8, 2024) With the use of its emergency authorityânot used in nearly 40 years, the U.S. Environmental Protection Agency (EPA) on August 7 banned a pesticide (the weed killer Dacthal or DCPAâdimethyl tetrachloroterephthalate) under the âimminent hazardâ clause of the federal pesticide law. At the same time, the agency is exercising its authority to prohibit the continued use of Dacthalâs existing stocks, a provision that EPA rarely uses. EPA identified serious concerns about fetal hormone disruption and resulting âlow birth weight and irreversible and life-long impacts to children [impaired brain development, decreased IQ, and impaired motor skills] exposed in-uteroâ and finds that there are no âpracticable mitigation measuresâ to protect against these hazards. The last time EPA issued an emergency action like this was in 1979 when the agency acknowledged miscarriages associated with the forestry use of the herbicide 2,4,5-Tâone-half of the chemical weed killer Agent Orange, sprayed over people to defoliate the landscape of Vietnam in the war thereâwith the most potent form of dioxin, TCDD (2,3,7,8-Tetrachlorodibenzo-p-dioxin). While EPA has been congratulated for using its emergency authority, which it is obviously reluctant to use, and health and environmental activists say could be used broadly, the timeline […]
Posted in 2, 4, 5-T, Agriculture, Amvac, dacthal, Endocrine Disruption, Environmental Protection Agency (EPA), Miscarriage, Reproductive Health, Thyroid Disease, Uncategorized, US Department of Agriculture (USDA) | 2 Comments »
07
Aug
(Beyond Pesticides, August 7, 2024) Using mass spectrometry techniques, researchers in Luxemburg and France detect 69 biomarkers of pollutants and pesticidesâ12 of which are bannedâin hair samples from over 200 French children. This study, published in Environment International, is the first to target over 150 biomarkers in a single hair sample, which ârepresents the most comprehensive assessment of chemical exposome in humans,â the authors say. All children in the study were 3.5 years old and recruited from the Ătude Longitudinale Française depuis lâEnfance (ELFE) [French Longitudinal Study since Childhood] cohort in the country of France, a major pesticide consumer in Europe. The ELFE survey is a joint project between the French Institute for Demographic Studies (INED) and the National Institute of Health and Medical Research (INSERM), which provides the first comprehensive national scientific investigation of children in France by following them from birth to adulthood. Through analysis of hair samples from children in the ELFE cohort, this study evaluates pesticide exposure and compares it with prenatal exposure data from their mothers while also, according to the scientists, âinvestigat[ing] the roles of childrenâs biological sex and geographical differences as possible determinants of exposure.â Exposure to pesticides during early childhood poses significant […]
Posted in Azoxystrobin, Carbaryl, Children, Endosulfan, Fipronil, Heptachlor, hexachlorobenzene (HCB), International, Malathion, Metolachlor, organochlorines, Permethrin, Piperonyl butoxide (PBO), Synthetic Pyrethroid, tebuconazole | 1 Comment »
24
Jul
(Beyond Pesticides, July 24, 2024) The Center for Food Safetyâjoined by environmental, farm, and grassroots organizations including Beyond Pesticidesâsubmitted a groundbreaking petition yesterday to the U.S. Environmental Protection Agency (EPA), urging immediate action to address the presence of per- and polyfluoroalkyl substances (PFAS) in pesticides and pesticide containers. Numerous studiesâŻhave shown that the broad use of PFAS chemicals, and the resulting environmental contamination, has devastating impacts on public health, wildlife, and pollinators. Despite acknowledging PFAS as an urgent public health and environmental issue, EPA has upheld hundreds of registrations of pesticide ingredients that fall into the PFAS category. Furthermore, EPA has allowed the ongoing use of fluorinated pesticide storage containers, despite the agency itself finding that these containers leach PFAS chemicals into pesticide products.  PFAS, known as “forever chemicals” due to their ability to persist in the environment, are endocrine disruptors, which are linked to developmental issues, cancers, and organ damage. Crops can uptake PFAS from soil, resulting in dietary exposure for both the public and wildlife, while PFAS ingredients in pesticides can also leach into groundwater, contributing to widespread PFAS drinking water contamination. In recent years, EPA has acknowledged this critical issue and committed to addressing PFAS contamination outside […]
Posted in Announcements, contamination, Endocrine Disruption, Environmental Protection Agency (EPA), Pesticide Regulation, Uncategorized | 7 Comments »
04
Jun
(Beyond Pesticides, June 4, 2024) A study published in the most recent edition of the journal Ecotoxicology and Environmental Safety documents for the first time the presence of the herbicide glyphosate in human sperm. The study looked at 128 French men with an average age of 36 years who tested positive for glyphosate in their blood. Seventy-three out of the 128 men were found to also have glyphosate in their seminal plasma. Not only that, the amount of glyphosate in seminal plasma was nearly four times higher than what was detected in the blood.  Methods The study involved a population of 128 infertile French men from whom seminal and blood plasma samples were collected. The study was conducted at the “Pole SantĂŠ LĂŠonard de Vinci” medical center, located centrally near Tours, France. This region is recognized for its urban characteristics as well as being a major agricultural hub, particularly for grain and wine production. The study authors note, âThis area reflects the common herbicide exposure in Franceâ and the district ranks third highest in terms of pesticide purchases. While additional qualitative data was collected, only 47 of 128 participants fully completed a questionnaire about their profession, diet (organic or […]
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