17
Apr
(Beyond Pesticides, April 17, 2025) A literature review in Reproductive Sciences finds glyphosate (GLY) and glyphosate-based herbicides (GBH) impact women’s reproductive health, adding to the long list of documented harm from this widely used weed killer. The authors note, “Considering the widespread use of GLY, the controversy regarding its endocrine-disrupting potential and reproductive toxicity, and the innumerable lawsuits filed against Bayer and Monsanto by consumers for morbidities related to Roundup™ exposure, the purpose of this review is to summarize the current literature on the potential adverse effects of GLY and GBHs on the female reproductive tract and discuss possible clinical implications on reproductive health outcomes, including polycystic ovarian syndrome (PCOS), endometriosis, and female fertility.” Glyphosate and aminomethylphosphonic acid (AMPA), the primary metabolite (breakdown product) of GLY, are found throughout the environment in soil and water, as well as in samples of blood, urine, seminal plasma, and breast milk. Studies have detected residues in farmworkers, as well as “in the urine of 60–80% of the general public in the USA, including pregnant women and children.” (See studies here, here, and here.) The ubiquitous use of GLY and GBH, and subsequent persistence, threatens the health and well-being of all. Previous studies have […]
Posted in Agriculture, aminomethylphosphonic acid (AMPA), Bayer, DNA Damage, Endocrine Disruption, endometriosis, Glyphosate, Herbicides, Infertility, Monsanto, Oxidative Stress, Reproductive Health, Women's Health | No Comments »
08
Apr
(Beyond Pesticides, April 8, 2025) A comprehensive literature review in Environment & Health analyzes evidence from human biomonitoring, epidemiological studies, and toxicological studies that link adverse effects on women’s reproductive health, specifically impacting the ovary, to pesticide exposure. In examining the scientific literature, consisting of over 200 studies performed in the last 25 years, the authors find pesticide exposure threatens women’s health through ovarian dysfunction. “Epidemiological studies have shown that pesticide exposures are associated with early/delayed menarche [first occurrence of menstruation], menstrual cycle disorders, early menopause, long time to pregnancy, polycystic ovary syndrome, primary ovarian insufficiency, infertility, and implantation failure in women,” the researchers state. They continue, “Both in vivo [in animals] and in vitro [in cells] studies have shown that exposure to pesticides disrupts the estrous cycle, reduces the follicle pool, alters hormone levels, and impairs oocyte [egg] maturation.” These reproductive implications are noted with many different classes of pesticides, such as insecticides, including organochlorine pesticides (OCPs), organophosphates (OPs), pyrethroids, and neonicotinoids, as well as herbicides and fungicides. The authors, however, comment on present research gaps: “Much of the available epidemiological evidence focuses on legacy insecticides, such as OCPs, and a subset of insecticides that are still in use […]
Posted in acetamiprid, Atrazine, Bifenthrin, Chlorpyrifos, cypermethrin, DDT, Deltamethrin, Diazinon, fenvalerate, Glyphosate, Imidacloprid, Infertility, lambda-cyhalothrin, Lindane, Malathion, mancozeb, Oxidative Stress, Permethrin, Reproductive Health, Thiamethoxam, vinclozolin, Women's Health | No Comments »
31
Jan
(Beyond Pesticides, January 31, 2025) A recent cross-sectional study in Heliyon highlights the link between sleep disorders in Thai farmers and pesticide exposure. The authors find pesticide exposure as an important risk factor for sleep disorders after surveying 27,334 farmers over the age of 20 who had work experience for at least five years. The importance of sleep health is reflected both physically and mentally, as studies find “sleep deficiency increase[s] mortality and various health complications, including hypertension, obesity and type 2 diabetes, cardiovascular diseases, mood disorders, and neurodegenerative disorder.” Additional studies find that these issues are compounded when sleep health is affected by environmental factors such as pesticide exposure. (See previous Beyond Pesticides’ coverage here and here.) The researchers report: “The study found a positive association of 19 individual pesticides (twelve insecticides, two herbicides, and five fungicides). Some associations demonstrated a dose-response pattern. Additionally, the study revealed that women are at a higher risk of sleep-related issues with pesticide exposure compared to males. These results not only substantiate existing literature but also unveil several new individual pesticides that may impact sleep health.” Focusing on study participants in Thailand, which is “characterized by heavy pesticide use and minimal protective measures, […]
Posted in Benomyl, Brain Effects, Carbaryl, Carbendazim, Carbofuran, Chlordane, Chlorpyrifos, copper sulfate, DDT, Diuron, Endosulfan, Farmworkers, Imidacloprid, Metalaxyl, Methamidophos, Methomyl, Mevinphos, Occupational Health, Paraquat, Sleep Disorders | No Comments »
21
Aug
(Beyond Pesticides, August 21, 2024) A literature review, published this month in the Journal of Agricultural and Food Chemistry, explores levels of pesticide residues found in samples of human urine with environmental exposure and dietary intake and confirms prior findings about the benefits of an organic diet. Similar to past findings, lower concentrations of chemicals are detected in the urine of participants who report eating an organic diet. By analyzing 72 scientific research studies published between 2001 to 2023, the review assesses routes of exposure and “explores urinary concentrations and detection frequency of metabolites of organophosphates and pyrethroids, as well as herbicides such as 2,4-D and glyphosate,” the authors say. While “exposure to pesticide residues is influenced by a variety of demographic factors, including occupation, agricultural practices, seasonal variations, residence, diet, age, and gender,” the authors say, the concentrations of pesticides and their metabolites in human urine highlights the disproportionate risk to certain groups as well as the overall threat to the health of humans and the environment. Pesticide exposure can occur from dermal/skin contact or inhalation, through residence or work, and with dietary intake. “Pesticides in urine can be detected as parent compounds, specific metabolites corresponding to a specific […]
Posted in 2,4-D, Alternatives/Organics, Chlorpyrifos, cypermethrin, Deltamethrin, Farmworkers, Glyphosate, Metabolites, Permethrin, Synthetic Pyrethroids | No Comments »
20
Jun
(Beyond Pesticides, June 18, 2024) As part of its update to the proposed U.S. Environmental Protection Agency (EPA) Endangered Species Act (ESA) Workplan, the agency held a public webinar on June 18, 2024, which provided an overview of the agency’s “Mitigation Menu Website” for “reducing pesticide exposure to nontarget species from agricultural crop uses.” [Check back to see webinar when posted by EPA.] After court decisions forced EPA to develop a strategy to meet its statutory responsibility to protect endangered species from pesticide use, the agency recognized that it is, in its own words, “unable to keep pace” with its legal obligations. Despite this acknowledgement, the agency said it would “provide flexibility to growers to choose mitigations that work best for their situation.” In this spirit, a range of people, including grower groups, gathered earlier in the year for a series of workshops in the Pacific Northwest to discuss possible mitigation measures. According to a report written by commercial beekeeper Steve Ellis (more background), concrete decisions were not reached at the workshops as participants recognized the complexities in crafting pesticide product label restrictions to protect endangered species. Mr. Ellis concluded: “If it’s so complex that it’s impossible, then no one […]
Posted in Agriculture, and Rodenticide Act (FIFRA), Endangered Species Act (ESA), Environmental Protection Agency (EPA), Herbicides, Pesticide Drift, Pesticide Regulation, Uncategorized, Wildlife/Endangered Sp. | No Comments »
24
Apr
(Beyond Pesticides, April 24, 2024) On April 16, 2024, the U.S. Environmental Protection Agency (EPA) posted an “update” to the Draft Herbicide Strategy Framework (Draft Herbicide Strategy Framework to Reduce Exposure of Federally Listed Endangered and Threatened Species and Designated Critical Habitats from the Use of Conventional Agricultural Herbicides) that was released last summer, weakening aspects of the agency’s efforts to “protect” endangered species from herbicide use. The update outlines three types of modifications to the Draft Strategy, including “simplifying” its approach, increasing growers’ “flexibility” when applying mitigation measures, and reducing the mitigation measures required in certain situations. By reducing the stringency of the Strategy, advocates are again questioning EPA’s commitment to fulfilling legal requirements under the Endangered Species Act (ESA) or protecting endangered species and their habitats in the midst of an unprecedented rate of global extinction. ESA is celebrated as one of the most far-reaching conservation laws globally, credited with preventing the extinction of 99 percent of those species the government targets for protection, according to the U.S. Fish and Wildlife Service (USFWS). ESA establishes a framework to categorize species as “endangered” or “threatened,” granting them specific protections. Under ESA, EPA is required to consult with relevant agencies […]
Posted in Agriculture, Alternatives/Organics, Announcements, Disease/Health Effects, Drift, Endangered Species Act (ESA), Environmental Justice, Environmental Protection Agency (EPA), Farmworkers, Fish and Wildlife Service (FWS), Habitat Protection, Herbicides, Increased Vulnerability to Diseases from Chemical Exposure, National Organic Standards Board/National Organic Program, Organic Foods Production Act OFPA, organophosphate, Parks for a Sustainable Future, Pesticide Efficacy, Pesticide Mixtures, Pesticide Regulation, Pollinators, U.S. Geological Survey, US Department of Agriculture (USDA), Wildlife/Endangered Sp. | No Comments »
05
Mar
(Beyond Pesticides, March 5, 2024) Buried in a court decision in February that determined that the U.S. Environmental Protection Agency (EPA) violated the law in allowing harm associated with the herbicide dicamba’s registration is language that permits the damages to continue through this year’s growing season. The judge’s ruling, deferring to EPA’s interpretation of the existing stock provision in the federal pesticide law, continues a pattern of “existing stock” allowances that permit hazards to continue well after a finding of harm or noncompliance. This process contrasts with the issuance of a product recall, which is typically done when pharmaceuticals are found to violate safety standards. Despite the finding of dicamba’s harm and EPA’s failure to comply with standards, the continued use of the weed killer through the 2024 growing season is effectively authorized in a decision of the U.S. District Court of Arizona, which vacates the EPA’s 2021 authorization of the use of three over-the-top (OTT) uses of dicamba-based herbicide products. In response, EPA issued an existing stocks order. EPA’s pattern of allowing the use of existing stocks has long been a concern for public health and environmental advocates, who have called for the discontinuance of use upon findings of […]
Posted in Dicamba, Drift, Environmental Protection Agency (EPA), Genetic Engineering, Herbicides, Litigation, Uncategorized | No Comments »
