(Beyond Pesticides, April 10, 2026) An important study not previously covered in Daily News, “Use of Genetically Modified Organism (GMO)-Containing Food Products in Children,” raises serious concerns about children’s dietary exposure to pesticides, particularly the weed killer glyphosate, that are heavily used in the production of genetically engineered crops. Published in Pediatrics by the American Academy of Pediatrics, the lead authors Steven A. Abrams, MD, FAAP, Jaclyn Lewis Albin, MD, FAAP, and Philip J. Landrigan, MD, FAAP call attention to the widespread use of genetic engineering (GE) and GMOs in the U.S. food supply and the subsequent health risks for children and consumers. The authors, in collaboration with the Committee on Nutrition, Council on Environmental Health and Climate Change Executive Committee, and additional medical professionals and researchers, also maintain that pediatricians have the opportunity to provide education and “lead conversations with families about the health impact of certain foods, provide nutritional guidance, and help filter the overwhelming volume of information.” By supporting parents in making informed nutrition choices, pediatricians can help shape decisions that impact the long-term health of children and advocate for choosing organic certified products. As the authors state: “Although GMO technology could be used to increase the micronutrient […]

(Beyond Pesticides, March 27, 2026) In a study of birth outcomes in Arizona, published in the Journal of Exposure Science & Environmental Epidemiology, researchers find that preconception and prenatal exposure to certain carbamates, organophosphates, and pyrethroids increases the risk of lower Apgar scores, a metric used to assess neonatal health at one minute and five minutes after birth. The results reveal that exposure to “several pesticide active ingredients at any point during preconception and/or pregnancy were associated with increased odds of low Apgar scores: the carbamates carbaryl and formetanate hydrochloride; the organophosphates diazinon and tribufos; and the pyrethroid cypermethrin.” This multi-institutional study, led by the University of Arizona with researchers from Harvard Chan School of Public Health and UCLA Fielding School of Public Health, provides novel insights, as it incorporates pesticide exposure over a 15-year period both before conception and throughout pregnancy. “To analyze associations of preconception and prenatal exposures to carbamate, organophosphate, and pyrethroid pesticide classes and 25 individual active ingredients with newborn Apgar scores to evaluate the relationship between these exposures and neonatal health,” the authors explain. They continue: “We used pesticide use registry and birth certificate data from 2006 to 2020, linked as part of the Arizona […]

(Beyond Pesticides, March 3, 2026) Research published in Critical Reviews in Toxicology (CRT) and Proceedings of the National Academy of Sciences (PNAS) documents the genetic and epigenetic (changes to gene function without altering the DNA sequence) effects to pesticide-exposed groups through early-life exposure and from transgenerational inheritance (passed down through generations). These studies highlight the complex nature of mechanisms of toxicity, as well as the various pesticide exposure routes that begin even prior to conception. The analyses evaluate general and specific pesticide exposure as reported in observational and laboratory research. Through a systematic review and meta-analysis of studies on “DNA damage, cytogenetic damage, DNA methylation, or gene expression outcomes associated with prenatal and early childhood pesticide exposure,” the CRT authors link genotoxic mechanisms and epigenetic alterations to adverse health outcomes while the PNAS study shows pesticide-induced epigenetic alterations in mammals across 20 generations that “suggest the maternal and paternal lineages can both induce and inherit epigenetic alterations that influence disease (e.g., kidney, testis, ovary, prostate) incidence, reproductive health (e.g., parturition, infertility), and overall fitness generationally.” As the CRT study states: “One of the main ways pesticides can cause harm is through genotoxicity—their ability to damage genetic material. This damage can […]

(Beyond Pesticides, January 14, 2026) Adverse neurodevelopmental outcomes in children 4–6 years old occur with reported maternal occupational exposure during pregnancy, as published in a study in PLOS One, according to research from Muhimbili University of Health and Allied Sciences in Tanzania and the Centre for International Health at the University of Bergen in Norway. “Our results show that self-reported maternal exposure to pesticides through direct spraying during pregnancy was associated with lower scores in social-emotional and executive function domains among children,” the authors state. Additionally, the authors note that they found an association between social-emotion scores in children and weeding practices of their mothers during pregnancy, as well as reduced overall neurodevelopmental scores following direct maternal pesticide exposure. The study, conducted through self-reported pesticide exposure from the mothers of 432 mother–child pairs in three horticulture-intensive regions in Tanzania and development and learning assessments of their children, reflects the “concerns about maternal occupational exposure during pregnancy and its potential impact on child neurodevelopment,” the researchers describe. Current risk assessments fail to properly capture the disproportionate risks to farmers and farmworkers with various routes of exposure, “particularly in horticultural settings where women of reproductive age represent a substantial proportion of the […]

(Beyond Pesticides, December 2, 2025) Recently published in Reproductive Toxicology, researchers in Denmark and Iceland investigate the impacts of pesticides on sex hormones, finding that “prenatal exposure to [the insecticide] chlorpyrifos and [weed killer] 2,4-D may affect the reproductive hormones in girls, but not boys, during minipuberty, which may have long-term implications.” Based on their analysis of urinary maternal concentrations of the pesticides and their metabolites and hormone levels in infants, the authors report, “This study examined the association between maternal pesticide exposure and pituitary, gonadal, and adrenal hormones in offspring during infancy.” The sex-specific findings highlight a public health concern with potentially long-lasting transgenerational effects. “We recruited pregnant women from 2010 to 2012 in the Odense Child Cohort, including 489 mother-child pairs,” the authors state. They continue: “Maternal urinary concentrations of the generic pyrethroid metabolite 3-phenoxybenzoic acid (3-PBA), the chlorpyrifos metabolite 3,5,6-trichloro-2-pyridinol (TCPY), and the herbicide 2,4-D were measured at gestational week 28. Serum concentrations of luteinizing hormone (LH), follicle stimulating hormone (FSH), testosterone (T), estrone (E1), estradiol (E2), 17-hydroxyprogesterone (17-OHP), Androstenedione (Adione), and Dehydroepiandrosterone sulfate (DHEAS) were assessed in infancy.” The results of the analyses show that in girls, higher maternal urinary TCPY and 2,4-D concentrations are significantly […]

(Beyond Pesticides, July 8, 2025) A commentary published in Science of The Total Environment showcases the occupational and environmental exposure pathways of fossil-fuel-based pesticide and fertilizer products that children across the globe face, particularly in rural areas of low- and middle-income countries. The authors underscore “the urgent need for multi-level systemic change, resilient health systems, and active stakeholder engagement,” which includes “support for safer and more sustainable agricultural practices.” This includes specific asks for governments “to offer technical assistance to producers and encourage organic and agroecological practices to ensure both environmental justice and food security.” Organic food systems, and criteria for land management systems more broadly, are critical to addressing the triple crises of biodiversity loss, public health collapse, and climate emergency. Organic law, as defined in the Organic Foods Production Act (OFPA) of 1991, is designed as a participatory process with accountability and transparency integral to the statutory language. The law creates the National Organic Standards Board (NOSB), comprised of farmers, consumers, and conservation organizations, a scientific expert, an organic certifier, and a retailer with the statutory authority to adopt binding recommendations to the Secretary of Agriculture on the National List of Allowed and Prohibited Substances. Simultaneously, the public […]

(Beyond Pesticides, May 30, 2025) The Making America Healthy Again (MAHA) Commission report, Make Our Children Healthy Again: Assessment, published on May 23, drew criticism from the pesticide industry and agribusiness allies for pointing to independent science that identifies a range of pesticide-induced health hazards.* The Commission, chaired by Robert F. Kennedy, Jr., Secretary of the Department of Health and Human Services (HHS), is composed of the heads of numerous agencies of the federal government and the White House, from the U.S. Environmental Protection Agency (EPA), the U.S. Department of Agriculture (USDA), and the Office of Management and Budget (OMB), to the Assistant to the President and Deputy Chief of Staff for Policy Stephen Miller. The MAHA Commission was established by Executive Order 14212 on February 13, 2025. Despite extensive citations to the science on pesticide hazards, the report includes a section on “Crop Protection Tools,” in which there is a repetition of chemical industry talking points that pesticide residues in food comply with existing tolerances, thus implying that pesticides in food are safe. (See USDA Pesticide Data Program Continues to Mislead the Public on Pesticide Residue Exposure.) However, overall the report’s introduction sets a tone that seeks to catalogue […]

(Beyond Pesticides, March 4, 2025) A study in GeoHealth of pediatric cancers in Nebraska links exposure to agricultural mixtures with the occurrence of these diseases. The authors find statistically significant positive associations between pesticide usage rates and children with cancer, specifically brain and central nervous system (CNS) cancers and leukemia. “Our study is the first to estimate the effect of an agrichemical mixture on the pediatric cancer rate in Nebraska,” the study authors share. “One significant advantage of our study is that we identified the pesticide consistently applied over 22 years in Nebraska counties and then estimated the overall mixture effect of these pesticides on pediatric cancer.” The elevated effect of pesticide mixtures, a reality that is not evaluated in the U.S. Environmental Protection Agency’s (EPA) pesticide registration program, was reported in Oecologia (2008), documenting harm to amphibian populations even if the concentration of the individual chemicals is within limits considered acceptable. (See additional coverage here.) There is a wide body of science highlighting the disproportionate risk of adverse health effects in children with pesticide exposure. Their small size and developing organ systems, propensity to crawl and play near the ground, tendency for frequent hand-to-mouth motion, and greater intake of […]

(Beyond Pesticides, February 20, 2025) Researchers at the University of Oregon found that the rollout of genetically engineered corn in the early 2000s, followed by exponential increases in glyphosate-based herbicides, “caused previously undocumented and unequal health costs for rural U.S. communities over the last 20 years.” Their results “suggest the introduction of GM [genetically modified] seeds and glyphosate significantly reduced average birthweight and gestational length.” The conclusions of this study emerge as fossil fuel advocates, including President Donald Trump, are mobilizing to pioneer “energy dominance” despite the market movement toward renewable energy. Just as chemical-intensive farmers and land managers continue to spray synthetic fertilizers and pesticides, a successful rollout of alternatives must rely on feeding the soil rather than the plant. Advocates continue to demand that elected officials and regulators embody the precautionary principle and scientific integrity in decision-making. Given the hostile federal climate on anything relating to holistic solutions, communities are coming together to move beyond input-dependent land management systems and adopt organic criteria of allowed and prohibited substances, mandatory public comment process, independent third-party certification, and a federal advisory board (National Organic Standards Board) consisting of farmers, environmentalists, consumers, scientists, economists, researchers, and other stakeholders, with binding recommendations […]

(Beyond Pesticides, November 26, 2024) A study in Environment International finds that young children who exhibit higher levels of pesticide metabolites in their urine show more pronounced neurobehavioral problems at the age of ten. Researchers in China document how exposure during early childhood, especially during the sensitive window before the age of two, is linked to hyperactivity/inattention problems such as attention deficit hyperactivity disorder (ADHD). While adding to the body of science connecting pesticide exposure to learning and developmental disorders, this study offers a “novel perspective on characterizing the fluctuation in repeated measurements of multiple environmental chemicals and identifying the potential critical windows,” the authors share. (See previous Daily News coverage here, here, and here.) The researchers analyze data from questionnaires and urine samples through the ongoing Sheyang Mini Birth Cohort Study (SMBCS), which is a long-term prospective cohort study that associates environmental chemical exposure during pregnancy and childhood to negative health effects. This data addresses combined pesticide exposures in young children with neurobehavior analyses at the age of ten to determine any correlation. Within the SMBCS, a total of 1303 pregnant women are enrolled. When the children reached ages one, two, three, six, seven, eight, nine, and ten years […]

(Beyond Pesticides, October 8, 2024) A comprehensive literature review in Endocrines, published in September, amasses hundreds of studies on endocrine-disrupting chemicals (EDCs) that showcase adverse effects on growth, development, reproduction, and metabolism. The authors, a team of scientists and academics from Brazil, shed light on the link between EDC use and thyroid dysfunction, leading to increasingly prevalent illnesses and deadly diseases.     EDCs are any synthetic or natural compounds that hinder endocrine system functions and create harmful effects on organisms. These chemicals can impact the thyroid gland, which is vital in producing hormones and plays a role in several body functions. As the researchers state, “Several EDCs have been classified as thyroid disruptors, impairing thyroid hormone [TH] production, synthesis, metabolism, transport, and/or actions. Notably, thyroid disorders are the second most prevalent endocrine disease worldwide, with incidence increasing significantly in recent years.” The authors continue, “[S]tudies have correlated this rise in thyroid dysfunctions and cancers with increased exposure to EDCs. Although many EDCs are linked to thyroid dysfunction, this review focuses on the deleterious effects of plasticizers, organochlorine pesticides, and per- and poly-fluoroalkyl substances on thyroid function. These contaminants are commonly found in food, water, and everyday products.” This review helps […]

(Beyond Pesticides, October 3, 2024) The American Academy of Pediatrics published a technical report in September on antimicrobial resistance, which it calls a global public health threat, identifying the health implications of antibiotic use in animal agriculture. The lead authors, both medical doctors from the Department of Pediatrics at Vanderbilt University Medical Center, note the rise in antimicrobial-resistant infections that result in increased morbidity, mortality, and health care costs for not only adults, but infants and children as well. “[A]ll use of antimicrobial agents exerts selective pressure that increases the risk of development of resistance,” the authors state, highlighting the importance of limiting antimicrobial uses. “Antimicrobial resistance is an organism’s ability to survive exposure to an antimicrobial agent that was previously an effective treatment. Resistance traits can be acquired either through new mutations or through transfer of genetic material between organisms,” the authors report. Antimicrobial-resistant pathogens, such as bacteria and viruses, can be transmitted “through the food supply, direct contact with animals, environmental pathways, and contact with infected or colonized humans,” they continue. Use of antimicrobial agents, especially over extended periods of time or with repeated exposure, can cause resistance to not only that agent, but to multiple agents. As […]

(Beyond Pesticides, February 13, 2020) Congress unanimously passed the Food Quality Protection Act (FQPA) in 1996 to increase protections for children from pesticide exposure. Unfortunately, according to a new study published in Environmental Health, the law is not being employed by the Environmental Protection Agency (EPA) to its full capacity. For most of the 59 pesticides reviewed by the study, EPA did not apply an additional FQPA safety factor and thereby missed an opportunity to protect children’s health. In fact, FQPA solidified EPA’s reliance on risk assessment calculations and mitigation measures that consistently fall short of adequate levels of protection because of serious data gaps, a failure to consider exposure to mixtures and synergistic effects, and a bias against consideration of alternatives (alternatives assessment)  that show toxic pesticides to be unnecessary.  FQPA establishes a safety standard applied to all food commodities that considers specific risks for infants and children. The law requires EPA to assess the “aggregate risk” (considering exposure from multiple sources) and “cumulative exposure” to pesticides that have a “common mechanism of toxicity.” FQPA mandates “an additional tenfold margin of safety for the pesticide chemical residue and other sources of exposure shall be applied for infants and children […]