25
Mar
(Beyond Pesticides, March 25, 2025) An editorial in Expert Review of Cardiovascular Therapy finds that triazole fungicides pose a significant risk of cardiotoxicity with “growing concerns regarding their safety for human health, especially in long-term exposure,” the authors share. After analyzing the known mechanisms of cardiotoxicity of triazole pesticides in mammals, they conclude that “the most effective approach to mitigating triazole-induced cardiotoxicity lies in prevention.” Triazoles, a class of fungicides, target fungi by inhibiting the biosynthesis of ergosterol, an essential component of their cell membranes. As the researchers share, “Compounds such as tebuconazole, propiconazole, and difenoconazole are among the most used triazoles in agriculture.” Triazoles are utilized as antifungal medications, despite the rise of resistant infections, in addition to their use as systemic pesticides on many fruit and vegetable crops, including grapes, wheat, corn, and soybeans.  As Beyond Pesticides’ previous coverage indicates, many triazole fungicides in the U.S. are registered for use despite evidence of endocrine disruption established over a decade ago in a U.S. Geological Survey report. These pesticides exhibit common mechanisms of toxicity often disregarded in U.S. Environmental Protection Agency (EPA) risk assessments, with a multitude of studies showcasing the myriads of health threats that the agency does […]
Posted in Cardiovascular Disease, difenoconazole, Endocrine Disruption, Fungicides, Oxidative Stress, Propiconazole, tebuconazole | No Comments »
14
Feb
(Beyond Pesticides, February 14, 2025) A study in the European Journal of Preventive Cardiology finds that organic food consumption lowers the risk of developing atherosclerotic cardiovascular disease (ASCVD). Heart health is important not just on Valentine’s Day, but every day. While celebrating with friends and family, consider spreading love in ways that promote long-term health and wellness with an organic meal paired with organic flowers and chocolates. Eliminating exposure to petrochemical pesticides and synthetic fertilizers, such as with an organic diet, mitigates disease risks including brain and nervous system disorders, cancer, endocrine disruption, and cardiovascular disease (CVD). In this latest study, the scientists and doctors analyze registered diagnoses of ASCVD from the Danish National Patient Register in comparison with the diets of a cohort of middle-aged women and men from the Danish Diet, Cancer and Health study. The eligible study participants, including 41,407 men and women of which 5,365 developed ASCVD, filled in a detailed 192-item food frequency questionnaire and a lifestyle questionnaire on their consumption of organic vegetables, fruit, dairy products, eggs, meat, and bread and cereal products. The authors report that the results show overall organic food consumption is associated with a 6% lower incidence rate of ASCVD. […]
Posted in Alternatives/Organics, Cardiovascular Disease, Holidays, men's health, Oxidative Stress, Pesticide Residues, Women's Health | No Comments »
04
Feb
(Beyond Pesticides, February 4, 2025) Adopting a fully organic diet can reduce pesticide levels in urine within just two weeks “by an average of 98.6%” and facilitate faster DNA damage repair relative to a diet of food grown with chemical-intensive practices, according to findings from a randomized clinical trial published in Nutrire. The authors explain that their finding “is likely due to two main factors: the presence of compounds characteristic of [an organic] diet, which may have high levels of antioxidants that can protect DNA and also induce DNA repair [], and the absence or decrease in the incidence of pesticides in this type of diet, which are recognized for their genotoxic effects and have the ability to affect the genetic repair system of organisms [].” Public health professionals and affected families continue to sound the alarm on the unprecedented rates of chronic illnesses, many linked to pesticide exposure, as well as the urgency in developing solutions that acknowledge the connection to policies governing agriculture, nutrition policies, and public health. Background and Methodology The purpose of this study is to identify any relationships in health effects of chemical-intensive versus organic diets in a two week-period. More specifically, the authors say […]
Posted in Alternatives/Organics, Children, Children/Schools, Disease/Health Effects, Environmental Protection Agency (EPA), Uncategorized | No Comments »
28
Oct
(Beyond Pesticides, October 28, 2024) STARTS WEDNESDAY—NATIONAL FORUM: IMPERATIVES FOR A SUSTAINABLE FUTURE. As scientific articles and regulatory reviews by the U.S. Environmental Protection Agency (EPA) focus on individual pesticides or families of pesticides and specific health outcomes associated with exposure, legislation introduced by U.S. Senator Cory Booker (D-NJ), S. 5084, Safe School Meals Act (SSMA), proposes a holistic response to the protection of children by banning pesticides in school lunches. While focused on the elimination of certain individual pesticides and other chemicals of known concern, the bill unilaterally allows children to be served food from certified organic farms. The overwhelmingly large body of scientific findings on the adverse effects of pesticides in the food that children eat in schools and generally. For example, last week Beyond Pesticides commented on EPA’s Draft Human Health and/or Ecological Risk Assessments for Several Pesticides, citing scientific findings that, “Neonicotinoids . . .have been found to affect mammalian nicotinic acetylcholine receptors (nAChRs) [which] are of critical importance to human brain function, especially during development and for memory, cognition, and behavior.” (See more here.) This month, Jennifer Sass, PhD, et al., in Frontiers in Toxicology, published a review of  unpublished rodent developmental neurotoxicity (DNT) studies […]
Posted in Alternatives/Organics, Children, Children/Schools, Disease/Health Effects, neonicotinoids, Take Action, Uncategorized | 1 Comment »
21
Aug
(Beyond Pesticides, August 21, 2024) A literature review, published this month in the Journal of Agricultural and Food Chemistry, explores levels of pesticide residues found in samples of human urine with environmental exposure and dietary intake and confirms prior findings about the benefits of an organic diet. Similar to past findings, lower concentrations of chemicals are detected in the urine of participants who report eating an organic diet. By analyzing 72 scientific research studies published between 2001 to 2023, the review assesses routes of exposure and “explores urinary concentrations and detection frequency of metabolites of organophosphates and pyrethroids, as well as herbicides such as 2,4-D and glyphosate,” the authors say. While “exposure to pesticide residues is influenced by a variety of demographic factors, including occupation, agricultural practices, seasonal variations, residence, diet, age, and gender,” the authors say, the concentrations of pesticides and their metabolites in human urine highlights the disproportionate risk to certain groups as well as the overall threat to the health of humans and the environment. Pesticide exposure can occur from dermal/skin contact or inhalation, through residence or work, and with dietary intake. “Pesticides in urine can be detected as parent compounds, specific metabolites corresponding to a specific […]
Posted in 2,4-D, Alternatives/Organics, Chlorpyrifos, cypermethrin, Deltamethrin, Farmworkers, Glyphosate, Metabolites, Permethrin, Synthetic Pyrethroids | No Comments »
