(Beyond Pesticides, July 14, 2025) With the rise in early onset cancer rates and mortality for breast, pancreatic, and gastric cancers, a wide and growing body of science linking pesticides to cancer, and associations between childhood cancer and pesticides, Beyond Pesticides is urging nationwide efforts to eliminate the use of cancer causing pesticides. Peter Hopewood, MD, FACS, writing in a bulletin in the American College of Surgeons says, “The coronavirus 2019 (COVID-19) pandemic has been in the healthcare spotlight since 2019, but the reality is that heart disease and cancer killed more people than COVID-19 in 2020 . . . and were our nation’s leading causes of death for decades before that. Among Americans younger than 85 years of age, cancer remains the leading cause of death.” Dr. Hopewood is convinced that “cancer has been an ongoing pandemic since life expectancy increased during the 20th century.”   In 1985, Imperial Chemical Industries and the American Cancer Society declared October “Breast Cancer Awareness Month” as part of a campaign to promote mammograms for the early detection of breast cancer. Unfortunately, most of us are all too aware of breast cancer. Detection and treatment of cancers do not solve the problem. A preventive approach is needed, not just awareness. Barbara Brenner, […]

(Beyond Pesticides, July 11, 2025) Pesticides and antibiotics are linked inextricably in the looming crisis of human and ecosystem health. Both started out as quasi-miraculous solutions to age-old human problems, yet it has been clear that the failures of each present severe challenges—and that they are synergistic because they trigger the same kinds of defensive mechanisms in their targets: insects, fungi, and weeds on the one hand, and microbes on the other. A review of contamination of waterways in India with pesticides and antibiotics, published in Environmental and Geochemical Health, recounts the many threats that arise when these chemicals mix and how their presence in water makes the problems much worse.    Globally, about five million people died in 2019 from infections with antibiotic-resistant microbes. By 2050, according to a World Bank estimate, antibiotic resistance could add $1 trillion to global health care costs and subtract $3.4 trillion from annual global gross domestic product. While the world slowly realizes the urgent need to counter antibiotic resistance, the role of pesticides in generating it has received less political and public attention. But there is no doubt that pesticides are strongly implicated. In fact, the resistance of microbes to antibiotics is no […]

(Beyond Pesticides, July 10, 2025) A study in People and Nature, with the goal of better understanding the social acceptability of introduced species management (ISM), often labeled “invasive species,” in the U.S., “conducted an online experiment with vignettes describing hypothetical but realistic ISM scenarios, varying targeted taxon (insect or plant), control method (mechanical, chemical and biological), risk severity (low and high) and type of non-target risk (to humans or native species).” This study highlights the debate on defining “invasive” species, as well as the low levels of acceptability by the general public for chemical controls such as pesticides. In addition, as pesticide hazards increase, the authors note that the responses show acceptance for only mechanical controls that incorporate manual removal of species, such as through pulling, cutting, clipping, or mowing. “Surprisingly, there was no significant difference in how respondents ranked risks to people and risks to native species,” the researchers report. This shows the values placed on both human health and biodiversity and “highlight[s] the need for evidence-guided ISM, which includes evidence of harmful impacts of introduced species, as well as risks and benefits of management activities, as one potential way to increase the social acceptability of non-native species management.” […]

(Beyond Pesticides, July 9, 2025) Policymakers in Tanzania are calling for increased investments in organic agriculture for the 2025/26 fiscal year budget, demonstrating the increase in political will to advance new systems of farming and land management after decades of relying on Green Revolution-style, or chemical-intensive, policies. On June 20, various ministers representing the national government presented speeches to Parliament on the national government’s plan and budget recommendations, as well as highlighting the previous fiscal year’s trends and use of funds.   Political and popular support for organic agricultural systems has gained momentum across the globe. Worldwide, organic farming practices quadrupled from 2000 to 2018, with over 180 countries supporting a global transition to organic agriculture. Newly published global survey data by the Research Institute of Organic Agriculture (FiBL) and International Federation of Organic Agriculture Movements – Organics International (IFOAM) reveal global organic agriculture to be at an all-time high, with 71.5 million hectares of farmland in production as of 2020. (See Daily News here). Farmer and agricultural cooperatives around the world, from Brazil to Madagascar and Togo, leverage organic systems to develop competitive business models in regional, national, and international markets. (See Daily News here.) The European Union, with […]

(Beyond Pesticides, July 2, 2025) An article in The New Lede, entitled Seeking answers to a cancer crisis in Iowa, researchers question if agriculture is to blame, documents case studies of cancer diagnoses linked to chemical-intensive agriculture. Current national cancer rates, according to the American Cancer Society, show that two million new cancer cases are projected to occur during 2025 in the U.S. Additional research predicts 618,120 cancer deaths this year as well, highlighting a crisis of great concern. A wide body of science links increased cancer risks with exposure to agricultural chemicals, including petrochemical pesticides and synthetic fertilizers. Previous coverage from Beyond Pesticides showcases the disproportionate health risks to farmworkers and their families, as well as those living near agricultural fields, associated with exposure to harmful toxicants. Recent research ties pesticide use to cancer diagnoses among farmer populations through a literature review of clinical trials, as well as epidemiologic, case-control, and experimental studies, from not only the U.S. but Brazil, India, France, Egypt, Columbia, Ecuador, Mexico, Italy, and Spain. (See Daily News here.) Additional risks for children, as reported in a study in GeoHealth, are noted in Nebraska as exposure to agricultural mixtures show statistically significant positive associations with […]

(Beyond Pesticides, July 1, 2025) Published in Water Research, a study highlights the various routes for pesticide contamination, with the results identifying the presence of over 80 substances in streams without adjacent agricultural land use. “Our findings underscore the necessity of further investigating the non-agricultural entry pathways of pesticides and biocides to effectively mitigate their impacts on streams in non-agricultural catchments,” the authors state. They continue, “These streams often serve as critical refuge habitats and sources of recolonization, making their protection essential for biodiversity conservation.” In analyzing nonagricultural streams, the researchers find pesticide contamination that, while lower than levels found in streams directly next to agricultural land, can occur through various routes and threatens biodiversity in essential ecosystems. As the authors describe: “Although pesticide concentrations were lower than in agricultural streams, the potential toxicity of pesticides was associated with a significant reduction in sensitive insect populations, as indicated by the SPEARpesticides index. Notably, 40% of the studied streams did not achieve a good status according to the pesticide specific SPEARpesticides indicator.” The SPEARpesticides indicator is used “to identify pesticide effects on the aquatic invertebrate community. It measures the abundance of pesticide-sensitive species (“species at risk”) in relation to the abundance […]

(Beyond Pesticides, June 30, 2025) Temperatures are hot—and getting hotter. Climate change is one of multiple crises that are compounding one another. Environmental disasters, including fires, floods, and severe weather events, are brought on or exacerbated by widespread reliance on disruptive chemicals, which played a role in a delayed start to the southern California rainy season, hurricane-force winds, and low humidity levels—all elevated by climate change. While climate change may be most apparent—record heat in much of the U.S. this month, 128°F in Death Valley last year, and extreme heat globally, last year’s earliest Category 5 hurricane on record, another volatile wildfire season, etc.—as crises are escalating in human disease and biodiversity collapse.  Extreme heat is the deadliest weather disaster—killing hundreds of thousands of people every year. Heat makes the health effects of pesticides and other pollutants more serious. Climate change is intensifying the impacts of habitat destruction and toxic chemicals on biodiversity. As the problems grow,  false claims of climate change mitigation require scrutiny. In this context, as an example, regenerative agriculture fails to require the elimination of petrochemical pesticides and fertilizers—major contributors to the climate crisis—while certified organic agriculture does. As organic is increasingly understood to be a climate solution, OrganicClimateNet last year launched an aggressive effort to build the base of organic farmers in the European Union (EU). As the […]

(Beyond Pesticides, June 26, 2025) A review article in Nature Reviews Earth & Environment highlights how the pesticides used in global crop production pose risks to ecosystems and human health through multiple pathways. As the authors note, “Once applied to crops, pesticides are transported through surface and groundwater flows, atmospheric dispersion and wildlife migration.” Residues in food products, such as fruits and vegetables, as well as bioaccumulation within animals that are consumed as food, also threaten consumers around the world, particularly those relying on international trade. The researchers note: “In this Review, we summarize the pathways through which synthetic pesticides transcend boundaries, focusing on the impacts of their use in food production… First, we explain how environmental flows contribute to transporting pesticides to regions far from their original source. Next, we examine the role of international food trade in causing transboundary exposure and impact of pesticide use.” As a result, the study calls for prioritizing biodiversity and human health through sustainable methods while maintaining yield to support the growing population. The use of pesticides in chemical-intensive agriculture has exponentially increased since their first synthesis in the late 1930s. “Globally, pesticides were applied on agricultural land at an average rate of […]

(Beyond Pesticides, June 24, 2025) As changes in the executive branch of the federal government upend expectations among environmental stakeholders, the regulation of food safety in the United States is being revealed as a rickety structure built over a century with unpredictable and sometimes contradictory additions, extensions, remodels, and tear-downs. In the short term, clarity is unavailable, but there have been calls for revision and strengthening of regulatory processes—requiring lawmaker and regulator willingness to incorporate the vast body of evidence that pesticides do far more harm than good, and that organic regenerative agriculture is the surest path to human and ecological health. News reports out of Costa Rica in May brought public attention to drafted legislation to ban pesticides in the country that the World Health Organization (WHO) has defined as “extremely or highly hazardous, or those with evidence of causing cancer, genetic mutations, or affecting reproduction, according to the Globally Harmonized System (GHS).” The headline sparked a relook in this Daily News at the current and historical failure of U.S. policy, which allows cancer-causing pesticides in food production and land management, despite the booming success of a cost-effective and productive, certified organic sector for which petrochemical pesticides are not […]

Image: Art Page submission from Sara Grantham, “Pollen Song.” (Beyond Pesticides, June 20, 2025) A study in Conservation Genetics, entitled “Organic farming fosters arthropod diversity of specific insect guilds – evidence from metabarcoding,” showcases the negative effect of chemical-intensive, conventional farm management on insect populations when compared to organically managed meadows. The researchers find that the diversity and biomass of flying insects are higher with organic land management by 11% and 75%, respectively. “We report a higher diversity on organic meadows in comparison with conventional ones, all over the diversity of flying insects and not only based solely on a few species-poor groups as in previous studies,” the authors state. They continue: “We found significant richness differences between management types and increased functionality on organic meadows. Our results imply the superiority of organic farming in comparison to conventional farming in the conservation of insect diversity.” The topic of insect biodiversity and the decline of insect populations over the last few decades, also referred to as the insect apocalypse, has been extensively covered by Beyond Pesticides. As previously reported in the Daily News, “Continued Decline in Insect Species Biodiversity with Agricultural Pesticide Use Documented,” insects provide many important services, such as […]

(Beyond Pesticides, June 17, 2025) Funding cuts in the current budget bill include drastic cuts in research essential to protect farmers, farmworkers, and their families. There are many federal agencies funding research, but among the most important of those funding research affecting farmers, farmworkers, and their families are the U.S. Environmental Protection Agency (EPA) and the National Institute for Occupational Safety and Health (NIOSH).   >> Tell Congress to restore funding that protects the health of farmers, farmworkers, and their families. EPA funding for the Bioecological Center for Research on Children’s Health (BeRCH) project was cut after almost two years. This project had the potential to address farmworker children’s health. Farmworker children can face many challenges–including poverty, language barriers, inadequate housing, discrimination, fear of family separation, exposure to agricultural chemicals, food insecurity, and migration. BeRCH was designed to identify, understand, and address the cumulative impacts on the health, development, and growth of farmworker children. The project goals were to examine farmworker children’s exposures to environmental toxins (pesticides, heavy metals, particulate matter) and non-chemical psychosocial stressors (poverty, food insecurity, trauma, discrimination, etc). Working in collaboration with the Florida State University (FSU) health clinic in Immokalee, the project would have examined threats, implemented strategies to improve health outcomes for farmworker children, and collaboratively established […]

(Beyond Pesticides, June 3, 2025) Chemical contaminants in wastewater have long been of concern, especially given the significant costs of upgrading wastewater treatment facilities to remove existing and emerging chemicals. In advancing chemical safety, one of the many regulatory determinations that Beyond Pesticides advocates for, prior to the allowance of any toxic chemical use, is the establishment of a realistic cleanup or disposal strategy. Yet, a plethora of petrochemical pesticides flood the market and contaminate the air, soil, water, and crops before poisoning humans and wildlife. A study in the Journal of Environmental Chemical Engineering uses the detectable levels of metabolites (breakdown products) of pesticides in wastewater to gauge exposure to populations living near flower bulb fields throughout the Netherlands. Wastewater samples were collected from five wastewater treatment plants (WWTPs) located in different parts of the Netherlands, with two of the locations (Tollebeek and Lisse) located near flower bulb fields and the other three representing control areas. The study finds that higher levels of chemicals correlate with proximity to agricultural fields and present a heightened health risk. The authors describe wastewater-based surveillance (WBS) as a complementary approach to human biomonitoring that they use “to assess the spatial differences in human […]

(Beyond Pesticides, May 29, 2025) A study, published in Environmental Toxicology and Pharmacology, “investigates genotoxic effects on farmers in Paraíba, Brazil, analyzing buccal mucosa cells [cells from inside the cheek] for DNA and cellular damage,” the authors write. In comparing data from 33 pesticide-exposed agricultural workers to 29 unexposed people in a control group, the researchers report that the “findings revealed significantly higher frequencies of cellular alterations and DNA damage among exposed farmers relative to the control group, with no significant impact from factors such as smoking, alcohol consumption, or family cancer history.” They continue, “These results underscore the genotoxic risks linked to prolonged pesticide exposure and highlight the necessity for stricter regulatory measures.” As Beyond Pesticides documents in Disproportionate Pesticide Hazards to Farmworkers and People of Color Documented… Again, farmworkers have been excluded from labor and occupational safety protection laws since their inception. The Occupational Safety and Health Administration (OSHA) defers all policy on pesticide protections to the U.S. Environmental Protection Agency (EPA), which has been widely criticized for providing inadequate worker protection standards. This study focuses on workers in Brazil, but represents issues that impact communities worldwide. “The agricultural sector plays a pivotal role in Brazil’s economy, encompassing […]

(Beyond Pesticides, May 28, 2025) A study in Birth Defects Research bolsters existing evidence that agricultural workers, and specifically Hispanic workers in California, are disproportionately bearing the burden of pesticide exposure. Caroline Cox, formerly of the Center for Environmental Health in Oakland, and Jonathan K. London, PhD of the University of California, Davis, examine how currently-used agricultural pesticides unequally affect communities along racial and ethnic gradients. Ms. Cox is a member of Beyond Pesticides’ board. Using 2022 data from the California Department of Pesticide Regulation (CDPR) and the U.S. Census Bureau, the researchers analyzed county, census tract, and school district data for the percentage of non-Hispanic White population in each population unit and determined the total agricultural use of commercial formulations of pesticides in the same units. CDPR reporting system’s granular data, including application locations at a resolution of one square mile, and the specific products, dates, and amounts of pesticides used, allows comparison of the data with demographic records. The results show that Hispanics’ exposure status is robust, independent of current or past data or “individual pesticides of public health concern.” Pesticides that harm reproductive health were strikingly concentrated among Hispanic populations. There is abundant evidence of racial and ethnic […]

(Beyond Pesticides, May 13, 2025) A study in Environmental Pollution examines ecological and health risks in farmland soil with pesticide contamination. “Although agricultural soil pesticide residues have long threatened the environment, a relatively complete system for evaluating their health and ecological risks has not yet been developed,” the authors state. In addressing this research gap, the study finds that “more than ten pesticides were detected in 98.62% of the soil samples, which changed the soil environment” and threatens the health of the soil microbiome. The authors continue, “This study investigated the correlation between pesticide residue risks and soil ecological security and human health, revealed the response characteristics of soil microbial communities under pesticide stress, and identified microbes strongly related to pesticide ecological risks.” Pesticides, as the authors emphasize, “inevitably pollute agricultural soil, affect the ecological environment, and pose a threat to human health.” (See studies here, here, and here.) With this in mind, they assess 50 selected pesticides in 145 soil samples from agricultural land in Zhejiang Province, China and calculate the associated risks to ecosystems and public health. In describing the importance of this research, the authors explain: “Pesticides are prone to leakage and drift in environmental media, turning […]

(Beyond Pesticides, May 12, 2025) A growing body of evidence demonstrates the environmental, health, climate, and economic benefits of organic agriculture. With the weakening of pesticide regulation, public health and environmental advocates say that the organic alternative takes on more importance. In this context, Beyond Pesticides and allies are calling on Members of Congress to support a bipartisan wave of legislation aimed at improving the U.S. food system and, specifically, a series of bills that support organic agriculture, including the Organic Science and Research Investment Act (OSRI), S.1385, the New Producer Economic Security Act, S.1237, (previously Increasing Land, Security, and Opportunities Act (LASO), H.R.3955, in 2023-24), the newly-introduced Organic Imports Verification Act (OIVA), S.1398, and the newly-reintroduced Agriculture Resilience Act (ARA) [bill number not assigned at the time of publication].  In April, Senators John Fetterman (PA-D) and Sen. Adam Schiff (CA-D), reintroduced OSRI, S.1385, to ensure “organics research is prioritized at the U.S. Department of Agriculture (USDA) and [increased] funding for research agencies and universities, [as well as ] provid[ing] much needed support to the organic farming industry.” The bill is cosponsored by Senators Kirsten Gillibrand (D-NY), Cory Booker (D-NJ), Jeff Merkley (D-OR), Tammy Baldwin (D-WI), Tina Smith (D-MN), Peter Welch (D-VT), Alex Padilla (D-CA), Ron Wyden (D-OR), and Angus King (I-ME).  The New […]

(Beyond Pesticides, May 9, 2025) Research in Advances in Modern Agriculture showcases how pesticide residues can threaten the health of soil nematodes and cause phytotoxic effects in cucumber plants. In assessing both the sprayed vegetables and the organisms within the soil, the authors find a negative correlation between pesticide exposure and soil nematode populations that is proportional to the application rates of the chemicals, as well as alterations in plant development. These impacts highlight potential wider effects on crop productivity, biodiversity, and human health. “Nematodes, which are microscopic worms inhabiting the soil, are vital contributors to soil vitality and the cycling of nutrients,” the authors share. “Nonetheless, the non-selective and widespread application of pesticides can negatively impact these organisms, leading to potential detriments in soil quality and plant vitality.” “Pesticide residues have the propensity to be absorbed and progressively accumulate as they traverse from soil to plants and subsequently to humans,” the researchers state. They continue, “The specific characteristics of the pesticide and its interactions with the body across different levels dictate whether it will be excreted without causing significant harm or if it will accumulate, potentially leading to enduring subclinical and clinical ramifications.” The impacts vary widely between organisms […]

(Beyond Pesticides, May 1, 2025) Pesticides by themselves are a grave threat to global health. As is global warming. As is antibiotic resistance. Each of these problems has to be analyzed in its own silo to reveal the mechanisms driving its dynamics. But eventually, it must be acknowledged that they actually converge. A common soil arthropod has clearly illustrated how this convergence creates synergistic effects: warming increases pesticide toxicity; pesticide toxicity triggers antibiotic resistance; antibiotic resistance spreads through horizontal gene transfer (movement through the environment to people) and predation. The consequences, not yet fully understood, are nevertheless emerging from accumulating research. A study published in the Journal of Hazardous Materials by scientists at six Chinese universities and research centers examines the convergence in springtails (Folsomia candida)—tiny insect-like animals that live in soils worldwide and are commonly used as laboratory subjects. The researchers exposed springtails to the neonicotinoid insecticide imidacloprid at three concentrations and three temperatures. In addition to measuring the springtails’ direct mortality, the researchers also investigated the microbes in the animals’ guts, checking for expression of genes involved in antibiotic resistance. The evidence is unequivocal: imidacloprid exposure at a soil temperature consistent with current and expected warming (30°C, or […]

(Beyond Pesticides, April 28, 2025) Despite the rising number of households without adequate access to food (18 million or 13.5% of households, or over 45 million people in 2023, including children, according to the U.S. Department of Agriculture’s Economic Research Service), government programs to support local food systems are being dismantled by the Trump Administration. For several years, farmers, schools, and food distributors have been working together to provide fresh, local food in schools and food pantries across the nation, thanks to two programs at USDA—the Local Food for Schools (LFS) Cooperative Agreement Program and the Local Food Purchase Assistance (LFPA) Cooperative Agreement Program.  >> Tell your U.S. Representative and Senators to make the Local Food for Schools (LFS) Cooperative Agreement Program and the Local Food Purchase Assistance (LFPA) Cooperative Agreement Program permanent through the Farm Bill. USDA has canceled the two programs that gave states, tribal governments, schools, and food banks money to buy local food from farmers. The LFS program awards money to states to buy local foods for schools and childcare institutions, and the LFPA program provides funding for state, tribal, and territorial governments to buy food produced within the state or within 400 miles of delivery destinations.  Hunger is […]

(Beyond Pesticides, April 18, 2025) A recent study published in Foods assesses the ability of the fungicide azoxystrobin (AZX) and naturally occurring toxins produced by certain fungi, known as mycotoxins, to display effects of cytotoxicity (cell damage). These effects were evaluated using three common mycotoxins found in food, including ochratoxin A (OTA), deoxynivalenol (DON), and T-2 toxin as mixtures with AZX within human hepatocarcinoma (HepG2) cell cultures. In analyzing combinations of these compounds at sublethal concentrations, the authors find modified toxicological behavior and synergistic effects that highlight the complexities of chemical mixtures, and potential threats to liver health through dietary exposure to both toxicants and toxins, that are not adequately regulated for their interactions. While fungicides, like azoxystrobin, are intended to prevent or control fungal diseases, resistance to these pesticides can increase the presence of fungi, and subsequent mycotoxins, on crops. This scenario allows for co-exposure of fungicides and mycotoxins within food products that present a risk to consumers. These chemicals can threaten human health individually, as the researchers confirm in their study, but present a greater threat in combination. The mixture of AZX with all three mycotoxins exhibits the highest toxicity, with synergistic effects at all tested concentration levels. […]

(Beyond Pesticides, April 17, 2025) A literature review in Reproductive Sciences finds glyphosate (GLY) and glyphosate-based herbicides (GBH) impact women’s reproductive health, adding to the long list of documented harm from this widely used weed killer. The authors note, “Considering the widespread use of GLY, the controversy regarding its endocrine-disrupting potential and reproductive toxicity, and the innumerable lawsuits filed against Bayer and Monsanto by consumers for morbidities related to Roundup™ exposure, the purpose of this review is to summarize the current literature on the potential adverse effects of GLY and GBHs on the female reproductive tract and discuss possible clinical implications on reproductive health outcomes, including polycystic ovarian syndrome (PCOS), endometriosis, and female fertility.”  Glyphosate and aminomethylphosphonic acid (AMPA), the primary metabolite (breakdown product) of GLY, are found throughout the environment in soil and water, as well as in samples of blood, urine, seminal plasma, and breast milk. Studies have detected residues in farmworkers, as well as “in the urine of 60–80% of the general public in the USA, including pregnant women and children.” (See studies here, here, and here.) The ubiquitous use of GLY and GBH, and subsequent persistence, threatens the health and well-being of all.  Previous studies have […]

(Beyond Pesticides, April 15, 2025) A study in Communications Earth & Environment, through field, greenhouse, and laboratory experiments involving three plant bug species, finds both species-specific and sex-specific sensitivity responses to neonicotinoid insecticide exposure—highlighting the threats to grassland insect communities that are disregarded in risk assessments. By assessing the effects of Mospilan®SG, with the active ingredient acetamiprid, the researchers determine that nontarget plant bug species are highly sensitive to neonicotinoids and face community-level harm with exposure. As systemic insecticides, neonicotinoids move through the vascular system of plants, expressing the poison through pollen, nectar, and guttation droplets. As persistent pesticides, these chemicals indiscriminately poison insects and organisms in the soil. “Although pesticides have been proposed as one of the main causes of insect decline, there are still few studies assessing their effects on non-target species under field conditions,” the authors state. They continue: “In this study, we address the existing research gap on insecticide exposure of non-target herbivorous insects, focusing on two main aspects: (1) realistic exposure scenarios, (2) community-level effects, i.e., differential sensitivity between closely related species and between sexes of the same species. We chose plant bugs (Heteroptera: Miridae) as a model group because they are one of the […]

(Beyond Pesticides, April 3, 2025) As highlighted by Beyond Pesticides in recent comments to the U.S. Environmental Protection Agency (EPA), chlorpyrifos (CPF) has been under scrutiny for decades due to associated adverse health effects, noted particularly in the extensive and consistent scientific evidence of neurotoxic dangers to children’s health. The latest research on CPF, published in Environmental Toxicology and Genes & Diseases, reveals additional threats to the immune system and male reproduction that are not captured in current EPA risk assessments of chlorpyrifos and raises serious health questions, given that residues are found throughout the food supply. CPF, a widely used organophosphate insecticide in agriculture, is a cholinesterase inhibitor that binds irreversibly to the active site of an essential enzyme for normal nerve impulse transmission, acetylcholine esterase (AChE), inactivating the enzyme. Many insecticides, including organophosphates and carbamates, target AChE, causing them to be highly toxic to both insects and mammals that have this enzyme as a crucial part of their nervous systems. The history of chlorpyrifos exemplifies the failure of pesticide law and policy, as this chemical, among many others, not only has direct adverse health effects but is contributing to the climate crisis, biodiversity collapse, and disproportionate levels of […]