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Daily News Blog

Archive for the 'Azoxystrobin' Category


19
Nov

Study Highlights Correlation Between Pesticide Exposure and Prostate Cancer in Men in the U.S.

(Beyond Pesticides, November 19, 2024) Researchers at Stanford University recently published a study in Cancer, an international interdisciplinary journal of the American Cancer Society (ACS), that reveals a correlation for numerous pesticides with increased prostate cancer occurrence and associated death. The study finds that exposure to 22 pesticides is positively associated with prostate cancer. The 22 pesticides include 2,4‐D, acephate, azoxystrobin, bifenthrin, carbaryl, chloropicrin, cloransulam‐methyl, cyhalothrin‐lambda, diflufenzopyr, diuron, glyphosate, hexazinone, linuron, methyl parathion, pendimethalin, propiconazole, sulfosate, thiamethoxam, thifensulfuron, tribenuron methyl, trifloxystrobin, and trifluralin. (See more on 2,4-D and cancer prevalence here and here.) As prostate cancer is a leading national health concern, the authors investigate agricultural pesticide exposure and compared it to prostate cancer incidence and mortality across counties in the contiguous U.S. “The geographic variation in prostate cancer incidence and mortality suggests that regional environmental factors, such as pesticide exposure, may contribute to the development of prostate cancer,” the researchers postulate. In comparing county‐level associations of 295 pesticides and prostate cancer reports, the authors were able to conduct an environment‐wide association study (EWAS) to determine any statistically significant links. “We acquired annual estimated total usage data (kg per county) for all pesticides reported and applied to agricultural crops grown […]

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22
Oct

Flooding Transports Pesticides from Streams to Soil and Plants, Threatens Terrestrial Food Webs

(Beyond Pesticides, October 22, 2024) A recent study, published through the American Chemical Society, analyzes pesticide contamination in riparian soil and plants as a result of flooding from streams in Germany. The authors hypothesize, and then prove, that frequently flooded sites have higher levels of pesticides present due to the pesticides in surface waters contaminating the soil. Results show that the plant vegetation in the contaminated soil then takes up the pesticides, which bioaccumulate and lead to higher contamination that can further cascade throughout the ecosystem and affect terrestrial food webs. “[O]ur study provides evidence from the field that nontarget plant species typical for riparian stream sites receive considerable pesticide exposure via flooding events,” the authors share. This exposure, and subsequent bioaccumulation in plants, threatens the food web, as many riparian plants are a vital food source for insects. According to the authors, flooding events, and their impact on pesticide contamination within soil and plants, are rarely investigated. This study, “measur[ing] 98 pesticides and metabolites in plants and root-zone soils sampled at five streams situated in an area in Southwest Germany characterized by intensive agricultural land use,” highlights the differences in contamination between frequently flooded and rarely flooded areas and […]

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07
Aug

Over 60 Biomarkers of Pollutants and Pesticides Found in Hair Analyses of French Children

(Beyond Pesticides, August 7, 2024) Using mass spectrometry techniques, researchers in Luxemburg and France detect 69 biomarkers of pollutants and pesticides—12 of which are banned—in hair samples from over 200 French children. This study, published in Environment International, is the first to target over 150 biomarkers in a single hair sample, which “represents the most comprehensive assessment of chemical exposome in humans,” the authors say. All children in the study were 3.5 years old and recruited from the Étude Longitudinale Française depuis l’Enfance (ELFE) [French Longitudinal Study since Childhood] cohort in the country of France, a major pesticide consumer in Europe. The ELFE survey is a joint project between the French Institute for Demographic Studies (INED) and the National Institute of Health and Medical Research (INSERM), which provides the first comprehensive national scientific investigation of children in France by following them from birth to adulthood. Through analysis of hair samples from children in the ELFE cohort, this study evaluates pesticide exposure and compares it with prenatal exposure data from their mothers while also, according to the scientists, “investigat[ing] the roles of children’s biological sex and geographical differences as possible determinants of exposure.” Exposure to pesticides during early childhood poses significant […]

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24
May

Study Finds Chemical Industry’s “Bee-Safe” Claim for Its Pesticides To Be False

(Beyond Pesticides, May 24, 2024) Even allegedly “low-toxicity” pesticides such as flupyradifurone (insecticide), azoxystrobin, and difenoconazole (fungicides) pose adverse health effects to solitary ground-nesting squash bees (Xenoglossa pruinose), according to a study published in Biological Sciences. Fungicide exposure led to less pollen collected per flower, while exposure to flupyradifurone (FPF) produced larger offspring (which make it more challenging for them to fly). Simultaneous exposure to the three pesticides “induced hyperactivity in female squash bees relative to both the control and single pesticide exposure, and reduced the number of emerging offspring per nest compared to individual pesticide treatments.” With United Nations Food and Agriculture Organizations-sponsored World Bee Day earlier this week, now more than ever advocates are calling for the elimination of toxic insecticide classes, such as neonicotinoids and butanolides, and their wholesale replacement with organic land management principles. This study was written by Sabrina Rondeau, PhD, postdoctoral Fellow in the Department of Biology at the University of Ottawa, and Nigel E. Raine, PhD, professor at University of Guelph’s School of Environmental Science. Published on March 20, 2024, the researchers delve into the individual and co-exposure impacts of two fungicides and one insecticide, which is important, given the documented synergistic effects […]

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27
Jun

Study Elevates the Connection Between Pesticides, the Gut-Brain Axis, and Disease

(Beyond Pesticides, June 27, 2023) Pesticides interfere with biological processes. This is their purpose. Unfortunately, they nearly always have unintended consequences, many of which have been ignored by their manufacturers. A new review article by Irish and Dutch researchers in the ISME Journal adds to the emerging scientific literature examining how pesticides affect the relationship between the human gut and the human brain (the “gut-brain axis”). Often called the “second brain” because it houses nerve cells and produces neurotransmitters, the gut-brain axis may be the most important locus where microbes and pesticides meet. The human gut plays host to a variety of microorganisms, ranging from bacteria and archaea to fungi, viruses and yeasts.[1] In a healthy person these microbes remain in balance and often cooperate both with each other and with human cells. The gut and the brain are deeply integrated through the vagus nerve and the neuroendocrine system. The vagus nerve is a treelike bundle of fibers extending from the lower part of the brain to nearly every body organ, but particularly the heart, lungs and digestive tract. The neuroendocrine system comprises specialized cells inhabiting nearly all the organs of the body that respond to signals from the brain […]

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26
Jan

Common Fungicide Adds to Growing List of Pesticides Linked to Gastrointestinal and Microbiome Damage

(Beyond Pesticides, January 26, 2023) A study published in Food Safety and Toxicology finds that the widely used fungicide azoxystrobin (AZO), used in food production and turf management, can disrupt the function of the intestinal (colonic) barrier responsible for the absorption of nutrients and defense against harmful substances. This and other similar data are important because the U.S. Environmental Protection Agency (EPA), with its required pesticide testing protocol, says that the chemical has “low acute and chronic toxicity to humans, birds, mammals, and bees,” and speaks to the need for the agency to modernize its registration requirements. [The agency does note that AZO is “is highly toxic to freshwater fish, freshwater invertebrates, and estuarine/marine fish, and very highly toxic to estuarine/marine invertebrates.] AZO is a broad-spectrum chemical used in wheat, barley, oats, rye, soya, cotton, rice, strawberry, peas, beans, onions, and a long list of other vegetables, as well as on lawns and golf courses, on a range of fungal diseases. The intestinal (colonic) barrier prevents the internal environment from damage caused by exogenous toxins to ensure internal homeostasis, impeding incidences of systemic inflammatory response syndrome (SIRS), sepsis, and multiple organ dysfunction syndrome (MODS). The intestines host a group of microorganisms that form […]

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16
Aug

Toxic Pesticide Residues on Over Half of U.S. Food, 1 in 10 Samples Violate Legal Limits, Says FDA

(Beyond Pesticides, August 16, 2022) Over half of all food samples tested by the U.S. Food and Drug Administration (FDA) contain the residues of at least one pesticide, and one in ten samples have levels that violate legal limits established by the U.S. Environmental Protection Agency (EPA). These findings, published by FDA this month in its 2020 Pesticide Residue Monitoring Report, are simply par for the course for government regulators, as FDA indicates the 2020 results “were consistent with recent years.” However, while reporting on the dangerous pesticides present in U.S. food has become routine for FDA, more and more Americans are rejecting regular exposure to unnecessary toxics in their food by going organic with their food choices, planting their own pesticide-free gardens, and encouraging their elected officials to embrace safer, sustainable land care policies.   FDA has conducted a review of pesticide residues on food on an annual basis since 1987, evaluating both domestic and imported foodstuffs into the US market. While EPA sets “pesticide tolerances,” also known as “maximum residue levels,” of allowed pesticide residues on certain foods, FDA (and USDA, for some specific items like meat, poultry, and eggs) is tasked with enforcing these provisions. Pesticide tolerances, […]

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01
Oct

Common Fungicides’ Use Leads to Algae Blooms

(Beyond Pesticides, October 1, 2019) Commonly used fungicides induce trophic cascades that can lead to the overgrowth of algae, according to research published in the journal Chemosphere. While the current process for regulating pesticides in the U.S. focuses on the acute toxicity of pesticides, and may consider some chronic impacts, real world complexities as described in the current study are not reviewed. This gap in our assessment can lead to significant adverse effects not just on individual species, but entire ecosystems. Researchers investigated how fungal parasites known as chytrids control the growth of phytoplankton. While some strains of chytrids are notorious for their impact to frog species, some do in fact provide important stopgaps within ecosystems. “By infecting cyanobacteria, parasitic fungi limit their growth and thus reduce the occurrence and intensity of toxic algal blooms,” says IGB researcher Ramsy Agha, PhD, co-author the study. “Whereas we usually perceive disease as a negative phenomenon, parasites are very important for the normal functioning of aquatic ecosystems and can — as in this case — also have positive effects. Pollution by fungicides can interfere with this natural process,” the researcher adds. The agricultural fungicides tebuconazole and azoxystrobin were tested on chytrid-infected toxic bloom-forming […]

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27
Sep

EPA Fines Syngenta $1.2 Million for Multiple Safety Violations under Settlement

(Beyond Pesticides, September 27, 2016)  Multinational pesticide manufacturer Syngenta Crop Protection was handed a  $1.2 million fine last week for multiple violations of federal pesticide law, according a settlement reached with the U.S. Environmental Protection Agency (EPA). EPA charged Syngenta with three major violations of the Federal Insecticide Fungicide and Rodenticide Act (FIFRA), including: (1) Failure to have repackaging agreement and/or maintain records on registered pesticides; (2) Distributing misbranded pesticides, and; (3) Failure to maintain data submitted for pesticide registration. However, under the consent agreement reached with EPA, the company neither admits nor denies the allegations. The settlement comes at a time of increased scrutiny of Syngenta, as the company is in the process of reregistering the herbicide atrazine, and Chinese National Chemical Corporation (ChemChina) continues its attempts to complete a $43 billion merger. While the plan appears to have cleared U.S. regulatory hurdles, European lawmakers have yet to sign off on the deal. “The repackaging, sale and distribution of unregistered and misbranded pesticides is illegal and puts people and the environment at risk. Users rely on accurate, up-to-date information about ingredients, directions for use, hazards and safety precautions,” said Anne Heard, Acting Regional Administrator for the Southeast in an […]

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04
Aug

Investigative Report Uncovers Dangerous Pesticide Misuse on Golf Courses in New York

(Beyond Pesticides, August 4, 2016) Complaints about a green residue that appeared on golfers’ shoes at Rye Golf Club in New York last spring prompted an investigative report by The Journal News/lohud.com, that  revealed what reporters are describing a region-wide “environmental toxic time bomb” caused by the over and misuse of pesticides throughout the state. The investigation uncovered (i) gaps in the oversight of millions of pound of toxic pesticides applied throughout the Lower Hudson Valley, (ii) heightened health risks in Westchester and Rockland counties where pesticides are used the most, (iii) significant flaws in pesticide data collected in the state of New York, and (iv) the failure of authorities to catch the illegal sale and use of unregistered pesticides. Rye Golf Club, which turned into a “field of dustbowls” within weeks of the green residue appearing on golfer’s shoes, had to close 18 putting greens, leading members to demand thousands of dollars in refunds and city leaders to address the severely damaged city-owned golf course. The cause of the mysterious green residue was later revealed to be the result of an application of a contaminated batch of the fungicide ArmorTech ALT 70, whose active ingredient is azoxystrobin. Rye Golf […]

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26
Jun

Wheat Embargo in Kansas Raises Concerns About Pesticide Residues

(Beyond Pesticides, June 26, 2008) Over 7,500 acres of winter wheat in 15 Kansas counties were sprayed improperly with the fungicide Quilt, forcing the Kansas Department of Agriculture to put an embargo on harvestable wheat from these fields pending further tests. Farmers are legally required to wait 45 days between spraying Quilt and harvesting wheat, but this spring’s wet weather encouraged many to ignore the rules. The problem was discovered during a paperwork check of custom applicators, which revealed that some fields had been sprayed as recently as early June. Quilt, manufactured by Syngenta and registered with the Environmental Protection Agency (EPA) in 2003, is a combination of the two active ingredients azoxystrobin and propiconazole. Propinconazole is a fungicide and antimicrobial with registered uses on food and feed crops, turf and ornamentals, as well as wood and material preservation. It is estimated that 1.7 million acres of wheat alone is treated with propinconazole each year. Azoxystrobin was first conditionally registered with the EPA in 1997 for use on turf. Information on the usage of the combination of these two fungicides is unavailable because of the recent registrations. Unfortunately, the USDA has cut funding for pesticide reporting (see Daily News of […]

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