(Beyond Pesticides, August 14, 2024) Pesticide exposure is linked to negative birth outcomes in a recent study in the American Journal of Epidemiology. This study adds to that body of science, but is novel research since, “Epidemiological studies of pesticide exposures and stillbirth in the United States have not been published in the past two decades, a time period that has seen dramatic changes in pesticide use compared to the 20th century,” the authors state. The study analyzes Arizona pesticide use records and birth certificates from 2006-2020. Researchers correlate mothers living within 500 meters of any pyrethroid, organophosphate (OP), or carbamate insecticide applications during specific windows before and during pregnancy with stillbirth. The authors focus on exposure during the prenatal period, as it is a susceptible time frame in which any contact with pesticides can negatively impact health. Numerous studies report several adverse birth and childhood outcomes with prenatal exposure. To link pesticide exposure and negative birth outcomes, Arizona records that encompass 1,237,750 births, 2,290 stillbirths, and 27 pesticides were analyzed. The authors “evaluate associations of pyrethroids, OPs, and carbamate insecticides with stillbirth by using data from the Arizona Pregnant women’s Environment and Reproductive outcomes Study (Az-PEARS), a project that […]

(Beyond Pesticides, May 18, 2023) A study published in Food and Chemical Toxicology finds pesticide residues in beehive products pose a safety risk from dietary consumption. Beehive products (i.e., bee bread, propolis, beeswax, and royal jelly) from beekeeping or apiculture are said to have nutraceutical (health and medicinal benefits) properties. However, a wide range of pesticide residues (i.e., tau-fluvalinate, coumaphos, chlorfenvinphos, chlorpyrifos, and amitraz), especially acaricides for killing ticks and mites in hives, may accumulate in beehive products up to concentrations that pose a potential health risk. Environmental contaminants like pesticides are ubiquitous in the environment, with 90 percent of Americans having at least one pesticide compound in their body. Many of these chemical compounds remain in soils, water (solid and liquid), and the surrounding air at levels exceeding U.S. Environmental Protection Agency (EPA) standards. Therefore, individuals still encounter pesticide compounds at varying concentrations, adding to the toxic body burden of those harmful chemicals currently in use. The research methodology includes a review of the scientific literature on pesticide contamination in hive products and a dietary risk assessment. The risk assessment calculation uses scientific studies to determine the recommended daily intake values and concentration data. Researchers compare exposure values in products to health-based guidance, determining the potential acute and […]

(Beyond Pesticides, September 21, 2022) Strawberry plants pollinated by wild bees exposed to neonicotinoid insecticides produce smaller berries than those pollinated by unexposed bees, finds research published in the journal PLOS One. The findings are yet another piece of evidence pointing to the need for major reforms in the way pesticides are evaluated and pollinators are protected in the United States. As decades of evidence have piled up on the dangers posed by long-lived, systemic, neonicotinoid insecticides, the U.S. Environmental Protection Agency (EPA) has done little to address the damage to pollinator populations, while needed legislation, the Saving America’s Pollinators Act, has languished in Congress without a hearing or a vote, despite having over 75 cosponsors. This new study describes a novel consideration for how neonicotinoids may harm pollinators and impact the food supply. “Previous studies have shown that clothianidin affects wild bees negatively in terms of foraging speed, development and reproduction. Our results indicate that it can also impair the bees’ ability to pollinate strawberry flowers,” says study coauthor Lina Herbertsson, PhD. Scientists established 12 outdoor cages each with 10 strawberry plants and 11 canola plants. For half of the cages, the canola plants were grown with seeds coated […]

(Beyond Pesticides, July 29, 2021) New research published in Environmental Health Perspectives finds nearly 300 different chemicals in pesticides, consumer products, and contaminated resources (i.e., food, water) increase breast cancer risks. Breast cancer is the most common cancer among women, causing the second most cancer-related deaths in the United States. Past studies suggest genetic inheritance factors influence breast cancer occurrence. However, genetic factors only play a minor role in breast cancer incidences, while exposure to external environmental factors (i.e., chemical exposure) may play a more notable role. There are grave concerns over exposure to endocrine (hormone) disrupting chemicals and pollutants that produce adverse health effects. Most types of breast cancers are hormonally responsive and thus dependent on the synthesis of either estrogen or progesterone. Hormones generated by the endocrine system greatly influence breast cancer incidents among humans. Several studies and reports, including U.S. Environmental Protection Agency (EPA) data, identify hundreds of chemicals as influential factors associated with breast cancer risk. Therefore, advocates point to the need for national policies to reassess hazards associated with disease development and diagnosis upon exposure to chemical pollutants. The study’s researchers note, “This study shows that a number of chemicals currently in use have the ability to manipulate hormones known to adversely […]

(Beyond Pesticides, April 23, 2020) Pesticide spray drift from adjacent farmlands expose butterfly larvae to lethal pesticide concentrations, according to research published in Environmental Toxicology and Chemistry by Iowa State University (ISU). Lack of previous experimental pesticide toxicity data makes it unclear as to what degree insecticides impact monarch butterfly (Danaus plexippus) productivity in milkweed (Asclepias spp.) habitats near pesticide-treated pasture. This study adds weight to the idea that pesticides are playing a role in the ongoing decline of this iconic butterfly, as researchers find insecticide drift from adjacent fields to be strongly associated with larval mortality. Future monarch butterfly conservation efforts should consider risks stemming from pesticide exposure when developing butterfly rehabilitation efforts, according to advocates. As co-author Niranjana Krishnan (ISU graduate student) states, “In order to make the best decisions about how and where to plant milkweed, we first need to find basic toxicity and exposure data.”  ISU researchers established monarch butterfly colonies by collecting larvae from roadside milkweeds, which they then reared in the laboratory for incubation. To analyze the relative toxicity of various insecticides on monarch butterflies, researchers applied normal field-application rates of each pesticide at different larval development stages. Scientists used a bioassay to measure the […]

(Beyond Pesticides, July 7, 2017) The active ingredients in commonly used bug sprays such as RAID leave significant residues that persist for over a year in the home, according to a study published by Brazilian researchers in the journal Environmental Toxicology and Chemistry. The pesticides tested, synthetic pyrethroids, have been linked to a range of health effects, most notably in children. The results of this study add to calls for homeowners to rethink a chemical-based approach to home pest control, in favor of simple, non-toxic practices. In the recent study, researchers compared the breakdown time of two synthetic pyrethroids, cypermethrin and beta-cyfluthrin, between laboratory conditions and those in an average home. Under lab conditions, with temperature controlled and without sunlight or ventilation, both active ingredients broke down little within the 112 day test period observed. However, the test house, where insecticides were applied according to indoor label conditions, displayed breakdown times similar to the lab results during the first 112 days. Researchers continued their observation of pyrethroids in the home for up to a year, finding after that period 44% of beta-cyfluthrin and 70% cypermethrin remained in household dust samples from the singular, original application. A 2014 study published by […]

(Beyond Pesticides, March 7, 2017) Another study, published by a team of French scientists in the journal Occupational and Environmental Medicine, links childhood behavioral problems to pyrethroid insecticide exposure. Synthetic pyrethroids are a class of insecticides that have increased in use over the past decade due to assumptions that they pose fewer risks to human health than older pesticide chemistries, such as organophosphates. However, this latest study is part of a growing body of research showing that pyrethroids share similar neurocognitive health concerns as these older pesticides. .   In this research, scientists investigate the interplay between pyrethroid exposure and behavioral problems through a longitudinal cohort study, which tracks levels of pyrethroid metabolites, or breakdown products, in the urine of mothers beginning between six and 19 gestational weeks and then in their children up through six years of age. Children’s behavior is measured through a screening questionnaire known as the Strengths and Difficulties Questionnaire (SDQ). SDQ measures how social a child is (altruism), whether the child has difficulty sharing problems or asking for help (internalizing disorders), as well as how defiant or disruptive a child is (externalizing disorders). The study controlled for a number of confounding factors, such as weight, education, location (rural or […]

(Beyond Pesticides, January 12, 2017) Yesterday marked a monumental event in the fight against pollinator declines, as the rusty patched bumblebee became the first bee species to officially be declared endangered by the U.S. Fish and Wildlife Service (FWS). According to FWS, endangered species designations are made when a species is “in danger of becoming extinct throughout all or a portion of their range.” Tom Melius, Service Midwest Regional Director for FWS, stated in a press release that, when it comes to this determination, “[FWS’s] top priority is to act quickly to prevent extinction of the rusty patched bumble bee. Listing the bee as endangered will help [the agency] mobilize partners and focus resources on finding ways right now to stop the decline.” Listed yesterday in the Federal Register, the ruling will go into effect February 10, 2017. This is a victory for environmental groups who have fought to protect the rusty patched bumble bee from widespread threats, such as habitat loss and pesticide use. According to FWS, the rusty patched bumble bee was once widespread across the United States and parts of Canada, but declined dramatically in the 1990s.  Since then, their populations have dwindled and their overall decline is estimated at 91 […]

(Beyond Pesticides, April 24, 2015) Two new studies reporting on the adverse effects of neonicotinoids on bees were published Wednesday in the journal Nature, adding to a growing body of scientific literature linking the controversial class of pesticides to the global decline in bee populations. The conclusions reached by the two studies find that not only does neonicotinoid exposure result in reduced bee density, nesting, colony growth, and reproduction, but also that bees in fact prefer foods containing neonicotinoid pesticides despite their adverse effects. Neonicotinoids affect the central nervous system of insects, resulting in paralysis and eventual death. These pesticides have consistently been implicated as a key issue in pollinator declines, not only through immediate bee deaths, but also through sublethal exposure that causes  changes in bee reproduction, navigation, and foraging. The science has become increasingly clear that pesticides, either working individually or synergistically, play a critical role in the ongoing decline of honey bees. Pesticide exposure can impair both detoxification mechanisms and immune responses, rendering bees more susceptible to viruses, parasites, and other diseases, and leading to devastating bee losses. In one study, “Seed coating with a neonicotinoid insecticide negatively affects wild bees,” Swedish scientists report that wild bees […]

(Beyond Pesticides, November 1, 2013) Insecticides commonly used in homes and schools are associated with behavioral problems in children, according to a recent study by Canadian researchers. The study investigates exposure to pyrethroid pesticides, used in more than 3,500 products, including flea and tick controls, cockroach sprays, and head lice controls. The study, Urinary metabolites of organophosphates and pyrethroid pesticides and behavioral problems in Canadian children, published in the journal Environmental Health Perspectives, raises serious concerns about the impact of pyrethroids, which are increasingly used as a replacement for organophosphates. This study uses data from the Canadian Health Measures Survey (2007-2009), a nationally representative survey, so researchers are able to apply these findings to the entire population of Canadian children. In a previous study among U.S. children, researchers at the National Health and Nutrition Examination Survey (NHANES) examined the metabolites of pyrethroids in children below the age of six. Similarly, they found pyrethroid insecticides in more than 70 percent of the samples, concluding that children had significantly higher metabolite concentrations than those of adolescents. Together these studies demonstrate that exposure is widespread, with real impacts to human health. In the recent study, researchers analyzed organophosphate and pyrethroid metabolites in the […]

(Beyond Pesticides, March 26, 2013) Scientists are learning more about the mechanisms bed bugs have developed to increase their resistance to the increasingly common class of pyrethriod pesticides. The study, published in the journal Scientific Reports in early March, adds further weight to calls from consumer health and environmental groups to adopt proven, non-toxic strategies to manage bed bugs and other household pest problems. After all, if alternatives exist, why put your family at risk with unsustainable, ineffective control methods? This latest research reveals something scientists had not suspected. Bed bugs are developing most of their resistance-associated genes on the outer layer of their shell. These genes either neutralize the insecticides before they can take effect, or slow down the toxins’ move towards the insects’ nerve cells. In addition, bed bugs in the study also show resistance developing within their nerve cells, the target site for the pesticides. This multilayered resistance is unique, scientists say, but, as Beyond Pesticides has long documented, pest resistance to pesticides is not. A 2011 study from Ohio State University reveals bed bugs’ ability to evolve hereditary changes in their production of certain enzymes, allowing them to excrete the toxins without being harmed. A study […]

(Beyond Pesticides, November 16, 2011) On November 9, 2011, the U.S. Environmental Protection Agency (EPA) issued its cumulative risk assessment for the pyrethroid class of insecticides, concluding that these pesticides “do not pose risk concerns for children or adults,” ignoring a wealth of independent data that links this class of chemicals to certain cancers, respiratory and reproductive problems, and the onset of insect resistance. The agency went as far to state that its cumulative assessment supports consideration of registering additional new uses of these pesticides, potentially opening the flood gates for manufacturers to bombard the market with more pyrethroid pesticides, endangering the health of the public. EPA issued the final pyrethins/pyrethroid cumulative risk assessment in the Federal Register and is requesting comment until January 9, 2011, including information that may be used to further refine the assessment. Pyrethroids are a widely used class of insecticides used for mosquito control and various insects in residential and agricultural settings. However pyrethroids are highly neurotoxic and have been linked to cancer, endocrine disruption, suppression of the immune system, and various reproductive effects. This class of chemicals includes permethrin, bifenthrin, resmethrin, cyfluthrin and scores of others. Read Beyond Pesticides’ factsheet “Syntethic Pyrethroids.” Once the […]

(Beyond Pesticides, August 11, 2011) A combination of eleven different kinds of commonly used pyrethroids were tested on mice in a new study which found that, at real-world exposure levels, the insecticides can produce heightened toxicity that is equal to the sum of each insecticide’s individual effect. The mixture of similar-acting insecticides works by over-stimulating electronic channels in the mouse’s brain cells and eventually causing death. This study adds to the growing body of research on the toxicity of pesticide combinations in nature and showcases the need for policy change because the current risk assessment approach to regulating pesticides fails to look at chemical mixtures and synergistic effects. The U.S. Environmental Protection Agency (EPA) currently regulates on a chemical-by-chemical basis, but as this study demonstrates, interacting chemicals can have synergistic effects at very low levels, where a “chemical cocktail” of multiple interacting chemicals combine to have greater effects than expected. Pesticides can also have a cumulative “toxic loading” effect both in the immediate and long term. Researchers exposed mice brain cells to eleven different food-use pyrethroid insecticides either singly or in a mixture in the study entitled ”Additivity of pyrethroid actions on sodium influx in cerebrocortical neurons in primary culture.” […]

(Beyond Pesticides, August 1, 2011) After sighting three Japanese beetles in the vicinity of Greenback Lane and Fair Oaks Boulevard in Sacramento County, California, state officials are scheduled to spray pesticides linked to cancer, reproductive and neurological effects. On August 2, the California Department of Food and Agriculture (CDFA) is scheduled to begin ground applications of carbaryl on fruit-bearing trees, and cyfluthrin on non-fruit-bearing trees and landscape plants in attempts to stave of attacks from the voracious Japanese beetle. Japanese beetles, a threat to turf grass as well as ornamental plants such as roses and cut flowers, have been detected in the Fair Oaks area, state officials said, but the ”˜infestation’ appears to be localized. To keep the ”˜infestation’ from spreading countywide, Juli Jensen, Acting Agricultural Commissioner, is urging residents in the area not to move plants or plant parts. The initial treatments will be directed at adult beetles and begins August 2 with applications of carbaryl on fruit-bearing trees, and cyfluthrin on non-fruit-bearing trees and landscape plants. Two weeks later, a second treatment will be applied and augmented by a granular imidacloprid to target grubs. The applications, to occur on approximately 100 properties, will be carried out by the […]