08
Oct
(Beyond Pesticides, October 8, 2024) A comprehensive literature review in Endocrines, published in September, amasses hundreds of studies on endocrine-disrupting chemicals (EDCs) that showcase adverse effects on growth, development, reproduction, and metabolism. The authors, a team of scientists and academics from Brazil, shed light on the link between EDC use and thyroid dysfunction, leading to increasingly prevalent illnesses and deadly diseases. Â Â Â EDCs are any synthetic or natural compounds that hinder endocrine system functions and create harmful effects on organisms. These chemicals can impact the thyroid gland, which is vital in producing hormones and plays a role in several body functions. As the researchers state, âSeveral EDCs have been classified as thyroid disruptors, impairing thyroid hormone [TH] production, synthesis, metabolism, transport, and/or actions. Notably, thyroid disorders are the second most prevalent endocrine disease worldwide, with incidence increasing significantly in recent years.â The authors continue, â[S]tudies have correlated this rise in thyroid dysfunctions and cancers with increased exposure to EDCs. Although many EDCs are linked to thyroid dysfunction, this review focuses on the deleterious effects of plasticizers, organochlorine pesticides, and per- and poly-fluoroalkyl substances on thyroid function. These contaminants are commonly found in food, water, and everyday products.â This review helps […]
Posted in Atrazine, Birth defects, Cancer, carbamate, Carbamates, Children, Chlorpyrifos, DDT, Dieldrin, Endocrine Disruption, Endosulfan, Fipronil, mancozeb, organochlorines, organophosphate, Permethrin, PFAS, phthalates, Propiconazole, pyrethroids, Synthetic Pyrethroid, Thyroid Disease, Women's Health | No Comments »
14
Mar
 (Beyond Pesticides, March 14, 2024) A recent review in the New England Journal of Medicine (NEJM) highlights the urgent need to address the widespread chemical pollution stemming from the petrochemical industry, underscoring the dire implications for public health. Tracey Woodruff, PhD, author and professor at the University of California San Francisco (UCSF), emphatically states in an email comment to Beyond Pesticides, “We need to recognize the very real harm that petrochemicals are having on peopleâs health. Many of these fossil-fuel-based chemicals are endocrine disruptors, meaning they interfere with hormonal systems, and they are part of the disturbing rise in disease.” Beyond Pesticides echoes this concern, noting that endocrine disrupting chemicals (EDCs) include many pesticides and are linked to a plethora of health issues such as infertility, diabetes, cardiovascular diseases, obesity, early puberty, as well as attention deficit hyperactivity disorder (ADHD), Parkinsonâs, Alzheimerâs, and childhood and adult cancers. (See Beyond Pesticidesâ Disease database here and news coverage here). The review further calls on the clinical community to advocate for policy changes aimed at mitigating the health threats posed by petrochemical-derived EDCs and climate change. Beyond Pesticides urgently calls for the elimination of petrochemical pesticides and fertilizers and advocates for a systemic […]
Posted in Agriculture, Alternatives/Organics, Body Burden, Cancer, Chemicals, Climate, Climate Change, contamination, Dow Chemical, Drinking Water, DuPont, Endocrine Disruption, Farmworkers, Groundwater, Herbicides, Livestock, Lung Cancer, multi-generational effects, National Organic Standards Board/National Organic Program, Oceans, PFAS, phthalates, Plastic, Reproductive Health, soil health, Synthetic Fertilizer, Synthetic Turf, Uncategorized | 1 Comment »
12
Aug
(Beyond Pesticides, August 12, 2022) Gestational (during pregnancy) exposure to endocrine disrupting chemicals (EDCs) like pesticides, per- and polyfluoroalkyl substances (PFAS), among others, may increase pediatric (child) liver injury and non-alcoholic fatty liver disease (NAFLD) risk, according to a study published in Environmental Health. Past studies associate exposure to EDCs with increased susceptibility to adverse health effects during critical fetal and childhood developmental periods. The World Health Organization (WHO), European Union (EU), and endocrine disruptor expert (deceased) Theo Colborn, Ph.D., classify over 55 to 177 chemical compounds as endocrine disruptors, including various household products like detergents, disinfectants, plastics, and pesticides. Endocrine disruption can lead to several health problems, including hormone-related cancer development (i.e., thyroid, breast, ovarian, prostate, testicular), reproductive dysfunction, and diabetes/obesity that can span generations. Because EDCs are ubiquitous because they are found in many products, studies report that these toxic chemical compounds are detectable in infants, children, and pregnant women. Furthermore, pregnant women can readily transfer compounds to the developing fetus through the placenta. Therefore, it is essential to understand the mechanism behind how harmful chemical exposure induces endocrine disruption during critical developmental periods. Researchers note, âConsidering the lack of studies on endocrine disruption and pediatric NAFLD, research like this highlights the need to understand the underlying […]
Posted in Endocrine Disruption, Liver Damage, Liver failure, PFAS, phthalates, Uncategorized | 1 Comment »
30
Jun
(Beyond Pesticides, June 30, 2020) A review of scientific literature on the toxic effect of environmental contaminantsâincluding pesticidesâpublished in the journal Toxicological Science, âThe Impact of Environmental Chemicals on the Gut Microbiome,â associates these chemicals to changes in the gut microbiome and other adverse health implications. The review, by researchers at the University of Illinois, looks at how environmental contaminants adversely effects and reinforce chemical disruption of the gut microbiome. It highlights the importance of evaluating how environmental contaminants, like pesticides, impact body regulation by gut microbiota. The study has significant implications for considerations that should be, but are not currently, a part of pesticide review and registration by the U.S. Environmental Protection Agency (EPA). Gut microbiota plays a crucial role in lifelong digestion, immune, and central nervous system regulation, as wells as other bodily functions. Through the gut biome, pesticide exposure can enhance or exacerbate, the adverse effects of additional environmental toxicants on the body. Since the gut microbiome shapes metabolism, it can mediate some toxic effects of environmental chemicals. However, with prolonged exposure to various environmental contaminants, critical chemical-induced changes may occur in the gut microbes, influencing adverse health outcomes. Karen Chiu, Ph.D., a graduate research fellow at the […]
Posted in Alternatives/Organics, Atrazine, Chemicals, Chlorpyrifos, Disease/Health Effects, Endocrine Disruption, Glyphosate, Gut Dysbiosis, Microbiata, Microbiome, Obesity, Oxidative Stress, phthalates, Uncategorized | No Comments »
24
Oct
(Beyond Pesticides, October 24, 2018) Bottlenose dolphins found along Floridaâs west coast contain detectable levels of phthalates, chemicals used in plastics, cosmetics and as inert ingredients in pesticide products, research published in the journal GeoHealth last month indicates. The study, published by scientists from the College of Charleston, South Carolina, is the first to find detectable levels of these toxic industrial byproducts in dolphins. Given the transient nature of urinary detection, the findings indicate that dolphins and other marine mammals are at increased risk of health effects related to phthalate exposure. Scientists sampled a total of 17 dolphins found in Sarasota Bay, FL over the course of two years. Of the 17, phthalates were detected in 12 individuals, or 71% of dolphins. The type of phthalates discovered was indicative of the source of the contaminant. With researchers detecting monoâ(2âethylhexyl) phthalate (MEHP) and monoethyl phthalate (MEP) most frequently. While MEHP is associated with plastic pollution, MEP is a breakdown product of diethyl phthalate (DEP), a compound that has been used in pesticide products as an inert ingredient. “These chemicals can enter marine waters from urban runoff and agriculture or industrial emissions, but we also know that there is a lot of […]
Posted in Agriculture, contamination, Inerts, Lawns/Landscapes, phthalates, Uncategorized | No Comments »
