(Beyond Pesticides, July 29, 2016)  A study released earlier this week finds lower IQ (intelligence quotient) in children born to mothers who during their pregnancy were living in close proximity to chemical-intensive agricultural lands where organophosphate pesticides were used. This study adds to the body of scientific literature that links prenatal exposure to organophosphate pesticides with lower IQ’s in children. Organophosphate pesticides, a relatively older generation of highly neurotoxic pesticides still widely used on farms in California, have been associated with a  broad range of diseases  in both children and adults.  This  latest study  supports health and environmental advocates’ call to eliminate these toxic pesticides in agriculture and move toward safer, sustainable, and organic management practices. The study, titled  Prenatal Residential Proximity to Agricultural Pesticide Use and IQ in 7-Year-Old Children, looks at 283 women and children from the agricultural Salinas Valley who are enrolled in the long-term Center for the Health of Mothers and Children in Salinas (CHAMACOS) study. Specifically, researchers looked at pregnant women living within one kilometer of agricultural fields where organophosphate pesticides were used. They found that at age 7, the children of those women had declines of approximately two IQ points and three verbal reasoning […]

(Beyond Pesticides, December 11, 2015) Milk contaminated with the long-banned and toxic organochlorine pesticide heptachlor in Hawaii has been found  in the brains of men that were more likely to develop Parkinson’s disease, according to a new study. This study adds to a large body of evidence linking pesticide exposure to Parkinson’s disease. Researchers of the study, titled “Midlife milk consumption and substantia nigra neuron density at death” and published in the journal Neurology, collected milk intake data from 1965 to 1968 for 449 men aged 45-68 years withpostmortem examinations from 1992 to 2004. Neuron density was measured in an area of the brain called substantia nigra (SN). As Parkinson’s develops, cells are destroyed in certain parts of the brain stem, particularly in the SN, a crescent-shaped cell mass. Measurements of brain residues of heptachlor epoxide, a heptachlor metabolite that is persistent and more toxic than its parent chemical, were also taken. “Among those who drank the most milk, residues of heptachlor epoxide were found in 9 of 10 brains as compared to 63.4%…for those who consumed no milk,” the researchers wrote. Neuron density was lowest in subjects who consumed the highest amounts of milk. The researchers looked at milk […]

(Beyond Pesticides, December 8, 2015) Exposure to common agricultural pesticides in early life leads to a measurable decrease in children’s lung functioning, according to researchers from the University of California, Berkeley. Organophosphate pesticides, a relatively older generation of crop chemicals still widely used on farms in California, have been associated with a broad range of diseases in both children and adults. This latest study adds to calls from health and environmental advocates to eliminate these toxic pesticides in agriculture, and move towards safer, sustainable, and organic management practices. The higher the rate of organophosphate exposure, the smaller a child’s lung capacity would be, scientists found. The UC Berkeley study traces exposure by looking at pesticide metabolites in urine five  times over the course of childhood (6 months to 5 years). Participants were part of the Center for the Health Assessment of Mothers and Children of Salinas (CHAMACOS), a longitudinal birth cohort study investigating the effects of pesticides and other environmental chemicals on the growth, health, and development of children in California’s Salinas Valley. For every 10-fold increase in pesticide metabolites measured in a child’s urine, an average of approximately 8% air function within the lungs was lost. “Researchers have described […]

(Beyond Pesticides, November 3, 2015) The U.S. Environmental Protection Agency (EPA) is proposing to revoke all food tolerances for the organophosphate insecticide chlorpyrifos (also known as Dursban), a neurotoxic pesticide produced by Dow AgroSciences that poses particular risks to children and farmworkers. If EPA’s rule is finalized, chlorpyrifos would be effectively eliminated from use in agriculture 15 years after consumer uses were discontinued. However, other non-food uses, including golf courses, turf, green house and mosquito control are not affected by this decision and will remain. EPA’s proposed rule came on the day of a court-ordered deadline from the U.S. Court of Appeals Judge for the Ninth Circuit, M. Margaret McKeown. In August of this year, Judge McKeown ordered EPA to respond to a petition filed by Pesticide Action Network North America and the Natural Resources Defense Council nearly nine years ago. The lawsuit called on the agency to ban all uses of the insecticide in light of scientific evidence and public comments ignored by the agency after its cumulative risk assessment for organophosphate insecticides. In 2012, EPA imposed “no-spray” buffer zones around public spaces, including recreational areas, schools, and homes to reduce bystander exposure risks. Earlier this year, the agency […]

(Beyond Pesticides, October 9, 2015) Last week, the Environmental Protection Agency (EPA) released preliminary human health and ecological risk assessments for seven organophosphate pesticides (OPs) and announced the public open comment period for those chemicals. These risk assessments come as a result of the required periodic registration review, as required by  the Federal Insecticide, Fungicides, and Rodenticide Act. In general, OPs are highly toxic and many have been voluntarily removed from the market, considerably restricted, or denied reregistration. Unfortunately, EPA continues to rely on risk mitigation for individual OPs instead of phasing them out altogether. Seven OPs ­ ­—dimethoate, dictrotophos, chloyrophos-methyl, tribufos, terbufos, profenofors, and ethoprop—are among the first wave of chemicals whose preliminary risk assessments have been completed under the registration review program. Each of these was found by EPA to inhibit the enzyme acetylcholine esterase (AchE), which ultimately leads to neurotoxic  central nervous system effects. This information is not new, however. In 2012, University College London found long-term low-level exposure to OPs produces lasting damage to neurological and cognitive functions. In 2013, at least 25 children died after eating school lunches contaminated by OPs. One OP in particular, chlorpyrifos, chlorpyrifos (Dursban), is currently under petition for the same […]

(Beyond Pesticides, August 14, 2015) Sublethal exposure to the organophosphate pesticide phosmet results in significant alterations in personality in individual spiders, according to a study published in the July print edition of the journal Functional Ecology. The study, titled “Under the influence: sublethal exposure to an insecticide affects personality expression in a jumping spider,” examines whether sublethal exposure to an organophosphate insecticide affects the consistency of individual behavior and disrupt behavioral correlations in the jumping spider Eris militaris (Araneae: Salticidae). Researchers measured the behavior of jumping spider adults by scoring them according to an open-field and a prey-capture assay, each conducted both before and after exposure to the insecticide phosmet. Researchers then measured the changes in repeatability, a measure of the extent of personality differences, and behavioral correlations between exposed and unexposed groups. Although there are no discernible effects on the population’s average behaviors, exposed individuals showed an average of 23 percent lower repeatability and the correlation between activity and prey capture is more strongly collapsed in females. “Bronze jumping spiders play an important role in orchards and fields, especially at the beginning of the agricultural season, by eating many of the pests like the oblique-banded leafroller, a moth that […]

(Beyond Pesticides, August 13, 2015) On Monday, a federal appeals court judge mandated that the U.S. Environmental Protection Agency (EPA) respond to a petition filed nearly nine years ago that seeks  to force the agency to restrict  the dangerous insecticide  chlorpyrifos (an organophosphate also known as Dursban). U.S. Court of Appeals Judge for the Ninth Circuit, M. Margaret McKeown,  delivered her opinion on August 10, stating that federal agencies should never practice the “venerable tradition” of putting off statutory requirements  when it comes to human health. The court issued the opinion and order in a lawsuit brought by Earthjustice on behalf of Pesticide Action Network (PAN) and Natural Resources Defense Council (NRDC), and gives EPA until October 31 to finally respond to the petition requesting to ban chlorpyrifos. EPA took a tentative step towards further regulating chlorpyrifos in a July 2015 announcement to ban remaining agricultural uses by April 2016 date. Unhappy with the uncertainty that EPA delivered, the court felt that a mandated deadline would expedite the process. On June 8, 2000, EPA administrator Carol Browner announced a voluntary agreement between the agency and industry leaders, including Dow AgroSciences, to ban all home and garden uses of Dursban, which […]

(Beyond Pesticides, July 7, 2015) In a sleight of hand,  the U.S. Environmental Protection Agency (EPA) announced plans last week to cancel all remaining agricultural uses of the hazardous insecticide chlorpyrifos by April 2016, and then left the door open for negotiations with the chemical’s manufacturer, Dow AgroSciences, to adopt  risk mitigation measures that would avoid a ban. Environmental groups are reacting to EPA’s announcement with guarded optimism, encouraging the agency to move forward with its planned cancellation of a highly toxic chemical that has remained on the market for far long. In June 2000, EPA announced a negotiated voluntary cancellation  with Dow that removed residential uses of chlorpyrifos (Dursban) from the market because of the neurotoxic effects to children, but allowed most agricultural uses to continue. As early as January of this year, EPA released a revised human health risk assessment for chlorpyrifos, finding that the chemical poses risk to farmworkers, and the drinking water of small watersheds. The assessment was, in part, in response to a petition submitted by Natural Resources Defense Council (NRDC) and Pesticide Action Network (PAN) in 2007, which called on the agency to ban all uses of the insecticide. Since the the 2000 cancellation, […]

(Beyond Pesticides June 4, 2015) Another study has found links between a commonly used household pesticide and attention deficit hyperactivity disorder (ADHD) in children and young teens. Researchers at Cincinnati Children’s Hospital Medical Center found an association between pyrethroid pesticide exposure and ADHD, particularly in terms of hyperactivity and impulsivity. These results reinforce the findings of a study led by a research team at Rutgers University earlier this year that found links between the pesticide deltamethrin and ADHD. In 2001, over concerns about adverse health consequences, the U.S.  Environmental Protection Agency banned several commonly used organophosphate (organic compounds containing phosphorus) pesticides from residential use due to the chemicals neurotoxic properties. The ban led to the increased use of pyrethroid pesticides, which are now the most commonly used pesticides for residential pest control and public health purposes. Pyrethroids, like deltamethrin, are commonly used in the home,  office buildings,  and on vegetable crops, gardens, lawns and golf courses. This shift to predominantly using pyrethroids is troubling, as they have oft been promoted as a safer choice than banned organophosphates, despite the fact that they pose many real threats to human health. Many recent studies show significant concern with this class of chemicals, […]

(Beyond Pesticides, March 13, 2015) Exposure to endocrine (hormone) disrupting chemicals (EDC) results in approximately € 150 billion ($162 billion) in health care costs in the European Union each year, according to panels of scientists tasked by the EU Commission to study their impact. “The shocking thing is that the major component of that cost is related to the loss of brain function in the next generation,” Philippe Grandjean, M.D. of Harvard University, one of the report’s authors, told the Guardian. EDCs, contained in common household products such as detergents, disinfectants, furniture, plastics, and pesticides, interfere with the body’s hormone system either by mimicking naturally produced hormones, blocking hormone receptors in cells, or effecting the transport, synthesis, metabolism or excretion of hormones. These impacts can result in devastating effects on one’s health, including behavioral and learning disorders, such as Attention Deficit Hyperactivity Disorder (ADHD), birth defects, obesity, early puberty, infertility, cardiovascular disease, and childhood and adult cancers. Nearly 100 percent of people have detectable amounts of EDCs in their bodies, according to the introductory guide to EDCs published by the Endocrine Society and IPEN. “Our brains need particular hormones to develop normally —the thyroid hormone and sex hormones like testosterone […]

(Beyond Pesticides, February 06, 2015) People who eat an organic diet have lower levels of pesticides in their bodies than those who eat conventional fruits and vegetables grown with pesticides, according to a new study published yesterday.  The study, “Estimating Pesticide Exposure from Dietary Intake and Organic Food Choices: The Multi-Ethnic Study of Atherosclerosis (MESA),” published in the journal Environmental Health Perspectives, looks at adult exposure to organophosphate pesticides (OPs). Scientists studied nearly 4,500 people from six U.S. cities and examined long-term dietary exposure to 14 OPs. This study group  was restricted to those who reported rarely or never eating organic food (“conventional consumers”). Scientists looked for signs of organophosphate exposure via urinary dialkylphosphate (DAP) levels and compared these levels to those who reported organic produce consumption habits. The scientists found that people who reported eating organic fruits and veggies at least occasionally had significantly lower DAP, or organophosphate residue, levels in their urine when compared to people who almost always ate conventionally grown produce. OPs are the most commonly used insecticides on conventional fruits and veggies, thus making OP exposure extremely prevalent. In fact, metabolites of organophosphate metabolites have been found in the urine of over 75 percent of […]

(Beyond Pesticides, January 7, 2015) On Monday, the U.S. Environmental Protection Agency (EPA) released a revised human health assessment for the insecticide, chlorpyrifos, which finds risks to workers who mix, load and apply chlorpyrifos, and that the chemical has the potential to pose risks to drinking water in small watersheds. The assessment also notes that EPA will retain the 10X (10-fold) safety factor to protect children from all routes of exposures. EPA’s latest finding confirms long-standing scientific data that  has documented chlorpyrifos’ toxicity to humans and environmental contamination. However, despite these findings, EPA proposes to place additional restrictions on chlorpyrifos’ use, instead of a widespread ban. This latest assessment updates the June 2011 preliminary human health risk assessment, which was widely criticized by environmental and farmworker groups. EPA is releasing this assessment based on new information received since 2011, including public comments. The assessment is, in part, in response to a petition submitted by Natural Resources Defense Council (NRDC) and Pesticide Action Network (PAN) in 2007, which called on the agency to ban all uses of the insecticide. In 2000, EPA orchestrated a voluntary cancellation with the manufacturer Dow AgroSciences of  most residential uses of chlorpyrifos to limit children’s exposure, […]

(Beyond Pesticides, October 15, 2014) A new study published in Environmental Health Perspectives finds a strong relationship between the use of pesticides and depression in farmers. One specific class of pesticide, organochlorines, was associated with a 90% higher chance of being diagnosed with depression. For fumigants, the increased risk was up to 80 percent. This study echoes the conclusion from an earlier French study which also reported that farmers using pesticides face  a greater risk of developing depression. The study, Pesticide Exposure and Depression among Male Private Pesticide Applicators in the Agricultural Health Study, examines possible associations between pesticide exposure and depression among male private pesticide applicators in the Agricultural Health Study (AHS). Over 21,000 applicators who enrolled in the study in 1993—1997 were followed and examined. The applicators were asked about depression when enrolled in the study and then again around 2010. Previous work with this AHS sample found a higher prevalence of depression among male applicators who reported past pesticide poisoning or use of pesticides from several different classes. However, this study examines specific pesticides, and finds that two types of pesticides, fumigants and organochlorine insecticides are positively correlated with depression and cumulative days of use. Those exposed […]

(Beyond Pesticides, July 2, 2014) According to a new study, few obstetricians offer their pregnant  patients advice on how to avoid environmental toxins that might harm their babies, even though doctors recognize that exposure to chemicals like pesticides, bisphenol-A (BPA), and metals can affect  a pregnancy. The study recommends that the medical community improve medical education and training, develop recommendations for prevention and less toxic alternatives, as well as lend support to policy change. The first of its kind study of prenatal counselling, published in the journal  PLOS ONE, Counseling Patients on Preventing Prenatal Environmental Exposures – A Mixed-Methods Study of Obstetricians, found that U.S. obstetricians and gynaecologists feel they lack the medical education and training, and evidence-based guidelines and tools for communicating potential environmental risks to patients. Exposure to environmental toxins, the researchers from the University of California, San Francisco (UCSF) found, is rarely discussed with pregnant patients, even though a national survey shows that 80 percent of physicians agree they should play a part in reducing patients’ exposure to toxins. But, of the 2,500 respondents, only one in five routinely asked  their  patients about these exposures, and just one in 15 said they received training on the harmful […]

(Beyond Pesticides, June 24, 2014) Research from the University of California, Davis CHARGE (Childhood Autism Risks from Genetics and the Environment) study finds that pregnant women who lived within a mile of agricultural fields treated with insecticides are more likely to have their child develop autism. The results of the CHARGE study, published in Environmental Health Perspectives, strengthens calls from public health and environmental groups urging regulators take a precautionary approach to agricultural chemicals and institute increased protections for those who live, work, or go to school near pesticide-treated fields. The CHARGE study looked at pregnant women’s addresses to determine their location relative to fields treated with pesticides. For women who lived less than one mile from crops sprayed with organophosphate insecticides during their pregnancy, researchers found the likelihood of their child being diagnosed with autism increased 60%. Women in the second trimester living near fields treated with chlorpyrifos, a widely used organophosphate insecticide banned for household use in 2001, are 3.3 times more likely to have their children diagnosed with autism. In response to a legal petition, the U.S. Environmental Protection Agency (EPA) in 2012 instituted risk mitigation measures for chlorpyrifos, including reduced application rates and no-spray buffer zones […]

(Beyond Pesticides, June 9, 2014) A recent talk given by Donald Weston, PhD, a professor emeritus in UC Berkeley’s Department of Integrative Biology, to a community group in San Jose, California warned residents about the dangers that  lawn care insecticides present to  local aquatic life. The talk focused on the problems synthetic pyrethroids and fipronil can have on Hyalella azteca and Chironomus dilutes. Increasing levels of pesticide runoff in local stream systems have not only led to decreased populations of these aquatic crustaceans, but also populations that have become resistant to pesticides. Aquatic invertebrates are extremely sensitive to pesticide runoff and different states around the country have struggled with creating pesticide regulations that foster a healthy aquatic ecosystem. A good way to reduce pesticide runoff is to transition away from toxic land care methods and adopt organic practices. Hyalella crustaceans, a tiny shrimp-like animal, are hypersensitive to pyrethroids, which are a class of insecticides used by professional lawn care companies and found in common products like Raid and mixed with fertilizer products like Scotts Turf Builder under the name SummerGuard. Chironomus dilutes, a red worm-like invertebrate, is sensitive to fipronil, which is used to kill fleas on dogs and cats […]

(Beyond Pesticides, May 2, 2014) A recent review, published in the International Journal of Environmental Research and Public Health, examines the interaction between widely used agricultural herbicides, like glyphosate, the active ingredient of Roundup products, and the risk of developing non-Hodgkin’s lymphoma (NHL). The study represents one of the most comprehensive reviews on the topic of occupational exposure to pesticides in scientific literature, demonstrating their clear harm to human health. The study, “Non Hodgkin lymphoma and occupational exposure to agricultural pesticide chemical groups and active ingredients: A systematic review and meta-analysis,” reviews almost thirty years of epidemiological research, examining occupational exposure of farmers to 80 active ingredients, and 21 chemicals groups to clarify their role in the development of NHL. Analyzing 44 papers, the study opens its discussion by mentioning the ”˜striking increase’ in incidents of NHL over the past 30 years. The study attempts to reconcile apparent trends of low mortality but high incidents of cancer among farm workers, pointing out that exposure to agricultural pesticides are often associated with signficint sub-lethal impacts. Researchers Maria Leon Roux, PhD., and Leah Schinasi, PhD. at the International Agency for Research on Cancer in the Environment and Radiation section, said that the […]

(Beyond Pesticides, May 1, 2014) A recent study, Reduction in urinary organophosphate pesticide metabolites in adults after a week-long organic diet, led by Liza Oates found lower trances of organophosphate metabolites in consumers that ate organic food for a week compared to those who ate a conventional diet. The study  adds to the scientific literature that shows consuming organic food minimize consumers’ exposure to pesticides residue. Because organic agriculture is a healthier system for consumers it is important we protect strict organic standards. The study, published in the Journal of Environmental Research, found that participants who ate a diet that was at least 80 percent organic had 89 percent lower levels of dialkylphosphates (DAPs), non-selective organophosphate metabolites, in their urine. The study was conducted in Melbourne, Australia with non-smoking participates between the age of 18 and 65. Participants were asked to eat a diet of conventional food for a week than on the morning of day eight participants provided a urine sample to the researchers. This process was repeated with the same participants after they spent a week eating at least 80 percent organic food. The levels of DAPs found in participants during the week in which they ate conventional […]

(Beyond Pesticides, November 1, 2013) Insecticides commonly used in homes and schools are associated with behavioral problems in children, according to a recent study by Canadian researchers. The study investigates exposure to pyrethroid pesticides, used in more than 3,500 products, including flea and tick controls, cockroach sprays, and head lice controls. The study, Urinary metabolites of organophosphates and pyrethroid pesticides and behavioral problems in Canadian children, published in the journal Environmental Health Perspectives, raises serious concerns about the impact of pyrethroids, which are increasingly used as a replacement for organophosphates. This study uses data from the Canadian Health Measures Survey (2007-2009), a nationally representative survey, so researchers are able to apply these findings to the entire population of Canadian children. In a previous study among U.S. children, researchers at the National Health and Nutrition Examination Survey (NHANES) examined the metabolites of pyrethroids in children below the age of six. Similarly, they found pyrethroid insecticides in more than 70 percent of the samples, concluding that children had significantly higher metabolite concentrations than those of adolescents. Together these studies demonstrate that exposure is widespread, with real impacts to human health. In the recent study, researchers analyzed organophosphate and pyrethroid metabolites in the […]

(Beyond Pesticides, October 3, 2013) According to new research, residents are more highly exposed to organophosphate and pyrethroid pesticides in New York City (NYC) than in the U.S. overall.  Researchers from the city’s Department of Health and Mental Hygiene reviewed the 2004 NYC Health and Nutrition Examination Survey (NYC HANES) to compare its pesticide exposure patterns in an urban environment with the nation as a whole. The NYC HANES includes a biomonitoring component to evaluate pesticide exposures by measuring concentrations of organophosphate and pyrethroid metabolites in urine. According to the authors, the findings underscore the importance of considering pest and pesticide burdens on cities, where a dense population results in a single exposure source affecting many people at the same time when regulating pesticide use. Organophosphate metabolites were measured in the urine of 882 New Yorkers, while 1,452 residents were tested for pyrethroid metabolites. As the researchers explain, the building density and disrepair in parts of NYC likely increased the chances of a pest infestation, which in turn can lead to the reliance on indoor pesticide use. By the 1980’s, organophosphates were the most common class of insecticides in the U.S., and were used indoors until the early 2000’s when […]

(Beyond Pesticides, July 22, 2013) Organophosphate pesticide poisoning from contaminated school lunches is suspected as the cause of deaths for at least 25 children in India. The children, aged four to 12, became sick after eating a lunch provided to them by the school. Several reports suggest the rice or cooking oil used to prepare the food contained unsafe levels of organophosphates, a highly toxic class of pesticides that have the same mechanism of action as nerve gasses. In the U.S. most organophosphates pesticides were phased out of residential use; however, these neurological poisons are still widely used on agricultural crops and for mosquito control. The schoolchildren began fainting soon after eating the contaminated food, and within hours at least 25 children were pronounced dead. Authorities discovered a container of organophosphate pesticides next to the cooking oil, but were not able to determine if this was the source of the poisoning or if the food itself was tainted with organophosphates. The school cooks, who both had children at the school that either fell ill or died from eating the food, told authorities that the cooking oil appeared different than usual, but the principal told them to use it anyway. The […]

(Beyond Pesticides, July 9, 2013) A recent pesticide contamination incident in Great Britain’s Kennet River has decimated aquatic invertebrate populations on a ten mile stretch of river between the towns of  Marlborough and Hungerford. The contamination occurred after a spill of the toxic pesticide chlorpyrifos entered a Marlborough sewage system. The lack of aquatic invertebrates could lead to a dramatic decline of the river’s chalk trout population. A similar incident occurred in Great Britain on the Wey River in 2003, and in Sussex Ouse in 2001. This recent calamity helps to underscore the importance for the U.S. Environmental Protection Agency (EPA), across the Atlantic, to fully implement pesticide restrictions that U.S. conservation groups are seeking to enforce through court action. The damage to the U.K. river may have been caused by, according to an Express article, only two tablespoons of the neurotoxic insecticide chlorpyifos. Members of the public have been advised by Britain’s Environment Agency to avoid skin contact with the water and not to eat fish caught from the river.  The contamination has occurred at the height of fly-fishing season. Environmental organizations are afraid that a decline in the number of aquatic invertebrates could lead chalk trout and other […]

(Beyond Pesticides, June 26, 2013) Pesticide use has sharply reduced the regional biodiversity of stream invertebrates, such as mayflies and dragonflies, finds a study published in the Proceedings of the National Academy of Science. While previous research has shown similar decreases in individual streams, this new study analyzes the effects of pesticides over broad regions. This is one of several recent findings that show pesticides pose a long-term threat to important ecosystems. The study, entitled Pesticides reduce regional biodiversity of stream invertebrates, notes that losses of biodiversity caused by anthropogenic activities during the past 50 years are unprecedented in human history. A team of researchers sampled 23 streams in the central plains of Germany, 16 in the western plains of France, and 24 in southern Victoria, Australia. Researchers classified streams according to three different levels of pesticide contamination: uncontaminated, slightly contaminated, and highly contaminated. Utilizing a model-based approach to account for other environmental variables, the team observed that losses in taxonomic diversity were, to a large degree, determined by the loss of species specifically vulnerable to pesticides. Overall, they found that there were up to 42% fewer species in highly contaminated than in uncontaminated streams in Europe. Highly contaminated streams […]