(Beyond Pesticides, July 10, 2020) A study published in June 2020 in Environmental Health journal is especially concerning for people who become, or plan to become, pregnant. It concludes that personal, agricultural, and household exposures to pesticides may increase the risk of a relatively rare fetal disorder called “holoprosencephaly.” The study finds that pre-conception and the first few weeks of pregnancy are the most vulnerable periods during which exposure can increase risk of this disorder, in which the embryo’s forebrain fails to develop into two distinct hemispheres. The study’s results reinforce Beyond Pesticide’s long-standing warnings of the dangers of pesticides to children and the necessity of shifting to a precautionary approach to the introduction and use of synthetic pesticides (and other chemicals) across all sectors. The importance of this shift is perhaps no more poignantly illustrated than in the impacts that pesticide exposure can have on new life. The study, conducted from 2016 through 2019 by researchers from NIH (the U.S. National Institutes of Health) and the University of Wisconsin–Madison, is a case-control study — one that compares subjects who have a disease or disorder with “controls” who do not have the disorder, comparing the frequency of exposure to a particular risk […]

(Beyond Pesticides, July 8, 2020) Efforts to control the transmission of malaria are encountering a big, though predictable, problem: the mosquitoes that transmit malaria are developing resistance to at least five of the insecticides that have been central to limiting transmission of the disease. A study released in late June reveals a dramatic increase in resistance to pyrethroid insecticides and DDT across sub-Saharan Africa. This signals the failure of a mainstay chemical approach to the spread of malarial mosquitoes; this same problem — resistance — is happening with chemical management of agricultural pests and weeds, and with antibiotics to treat human bacterial infections. This study underscores a point Beyond Pesticides has made repeatedly: resistance to pesticides (whether insecticides, herbicides, biocides, fungicides, or medical antibiotics) is nearly inevitable. The solution to containing the spread of malaria lies not in the use of more and different chemicals, but in nontoxic approaches that respect nature and ecological balance. Malaria is a sometimes deadly disease caused by female Anopheles mosquitoes infected with any of four varieties of the Plasmodium parasite. The disease kills roughly 400,000 people annually, with half that mortality in sub-Saharan Africa. The U.S. sees approximately 2,000 cases of malaria annually, primarily in […]

(Beyond Pesticides, May 8, 2020) At the height of Covid-19 impacts in the Northeast U.S., Massachusetts Governor Charlie Baker (R) and Lieutenant Governor Karyn Polito (R) filed emergency legislation at the Boston State House that would, according to their April 16 press release, “help the Commonwealth more effectively combat diseases transmitted by mosquitoes, including arboviruses like Eastern Equine Encephalitis (EEE) and West Nile Virus (WNV), by authorizing a coordinated, proactive, statewide approach to mosquito control activities.” Protecting the public from such diseases is an important public health mission. However, the Governor’s bill, H.4650, represents an alarming “over-reach” that would give unitary authority to the State Reclamation and Mosquito Control Board (SRMCB) to conduct mosquito control activities, including ineffective and toxic spraying, with virtually no effective oversight or transparency. Beyond Pesticides opposes this bill, whose passage would enable use of pesticides that can have respiratory and immune impacts — increasing health risks for everyone, but especially for the many people already at higher risk from Covid-19, despite the availability of ecological management approaches that eliminate the need for toxic chemicals. H.4650, An Act to mitigate arbovirus in the Commonwealth — was promulgated in response to a Massachusetts Department of Public Health […]

(Beyond Pesticides, April 23, 2020) Pesticide spray drift from adjacent farmlands expose butterfly larvae to lethal pesticide concentrations, according to research published in Environmental Toxicology and Chemistry by Iowa State University (ISU). Lack of previous experimental pesticide toxicity data makes it unclear as to what degree insecticides impact monarch butterfly (Danaus plexippus) productivity in milkweed (Asclepias spp.) habitats near pesticide-treated pasture. This study adds weight to the idea that pesticides are playing a role in the ongoing decline of this iconic butterfly, as researchers find insecticide drift from adjacent fields to be strongly associated with larval mortality. Future monarch butterfly conservation efforts should consider risks stemming from pesticide exposure when developing butterfly rehabilitation efforts, according to advocates. As co-author Niranjana Krishnan (ISU graduate student) states, “In order to make the best decisions about how and where to plant milkweed, we first need to find basic toxicity and exposure data.”  ISU researchers established monarch butterfly colonies by collecting larvae from roadside milkweeds, which they then reared in the laboratory for incubation. To analyze the relative toxicity of various insecticides on monarch butterflies, researchers applied normal field-application rates of each pesticide at different larval development stages. Scientists used a bioassay to measure the […]

(Beyond Pesticides, January 10, 2020) A new study by researchers out of the University of Iowa College of Public Health, published in JAMA (the Journal of the American Medical Association) Internal Medicine, demonstrates that greater exposure to pyrethroid insecticides is associated with higher risks of death from all causes and from cardiovascular disease. These compounds can be inhaled, ingested, or absorbed through the skin; they are highly neurotoxic, and have also been linked to certain cancers, endocrine disruption, and suppression of the immune system, as well as respiratory and reproductive impacts. The researchers gathered data, for 2,116 adults aged 20 or older, from the National Health and Nutrition Examination Survey. Each of those subjects had contributed a urine sample at some point between 1999 and 2002. Urine samples reflect levels of a pyrethroid metabolite (3-phenoxybenzoic acid) present, which in turn offer information about pyrethroid exposure. The researchers followed the participants until 2015; the research analysis was performed in the summer of 2019. Data were adjusted to accommodate multiple factors (age, sex, ethnicity, socioeconomic status, diet and lifestyle, smoking status, body mass index, and urinary creatinine levels). The co-authors report that subjects with the highest levels of metabolites had a 56% […]

(Beyond Pesticides, August 15, 2019) An article in the journal Plos One, “An assessment of acute insecticide toxicity loading (AITL) of chemical pesticides used on agricultural land in the United States,” shows that recent shifts in insecticide use—from organophosphates and carbamates to synthetic pyrethroids and neonicotinoids—have made a large contribution to the ongoing insect apocalypse. This shift to insecticides that target insects based on both selective toxicity and delivery method occurs within a context of shrinking habitat and biodiversity. The study, by Michael DiBartolomeis, PhD, Susan Kegley, PhD, Pierre Mineau, PhD, Rosemarie Radford, and Kendra Klein, PhD, presents a measure of acute insecticide toxicity loading that incorporates acute toxicity, quantity used, and the rate at which the insecticide degrades. Goulson et al. applied a similar measure in Great Britain that did not incorporate the rate of degradation. Both studies use the median lethal dose (LD50) to honey bees as a measure of acute toxicity and calculate the potential number of bee deaths based on the number of lethal doses of various insecticides applied in the field. In both cases, researchers used toxicity estimates for honey bees because they are widely available. Other insects may be more or less sensitive. The […]

(Beyond Pesticides, August 12, 2019) Once again, the Environmental Protection Agency (EPA) has rejected the evidence provided by independent scientists and sided with the pesticide industry promoting its products; this time, removing a safety for factor for children on some of the most widely used insecticides, synthetic pyrethroids. When EPA cannot do its job, it is time for Congress to step in. Tell Congress: To Protect Children, EPA Must Consider the Independent Peer-Reviewed Science, Not Bend to Industry Lobbying. In a move that challenges the preponderance of independent peer-reviewed scientific findings on children’s health, EPA recently stripped away protections that limit children’s exposure to class of chemicals associated with childhood cancer, autism other learning disorders, and asthma. The result of the agency’s actions will be a dramatic increase in the use of synthetic pyrethroids, insecticides found in indoor and outdoor bug sprays, bug bombs, and often used on conventionally grown fruits and vegetables. EPA, under the leadership of former fossil fuel lobbyist Andrew Wheeler, is embracing the positions of the pesticide industry while ignoring independent science and health and environmental groups. In 2017, the agrichemical industry trade group, Croplife America, submitted comments to EPA during its review of synthetic pyrethroids. The organization urged EPA to rely on a […]

(Beyond Pesticides, July 11, 2019) Pregnant mothers with higher concentrations of pesticide metabolites (breakdown products) in their urine are more likely to have children who develop symptoms of Attention Deficit/Hyperactivity Disorder (ADHD), according to research conducted by the University of Southern Denmark and Odense University Hospital. The results of this study are consistent with past findings from Rutgers University and Cincinnati Children’s Medical Center, indicating a need for researchers to determine causality, and pesticide regulators to rein in toxic insecticide use. The pesticides investigated by researchers were breakdown products of the organophosphate chlorpyrifos, and the synthetic pyrethroid class of insecticides. The residue of these chemicals are frequently detected on conventional, industrially farmed food products. Although chlorpyrifos is banned from residential use in the U.S., most household bug sprays such as RAID contain high amounts of synthetic pyrethroids. Among the 948 pregnant Danish women tested, 90% had some level of chlorpyrifos metabolites (3,5,6-trichloro-2-pyridinol) detected in their urine, and 94% were positive for the generic pyrethroid metabolite (3-phenoxybenzoic acid). Scientists continued to follow up with pregnant women’s children through the first five years of life. A child behavioral check list was completed to determine the relative level of ADHD symptoms. Concentrations of […]

(Beyond Pesticides, March 26, 2019) In a study investigating the carcinogenic effects of pesticide exposure by analyzing data on 316,270 farmers and farmworkers in the U.S., Norway, and France, researchers have identified elevated risk for non Hodgkin lymphoma (NHL) and some subtypes, linking glyphosate and large B-cell lymphoma. Other pesticides linked to the disease include the pyrethroid deltamethrin and chronic lymphocytic leukemia/small lymphocytic lymphoma; and terbufos and NHL overall. Researchers also found “inverse associations of NHL overall with the broader groups of organochlorine insecticides and phenoxy herbicides, after adjusting for exposure to other pesticides”; such inverse associations were not found with active ingredients within these groups. The research underscores how complex the science of pesticide impacts on human health, and on cancer incidence, can be. To wit: in evaluating 14 different pesticide categories and 33 individual, active chemical ingredients, Maria E. Leon, et al., conclude that associations of pesticides with the development of NHL appear to be (NHL) subtype- and chemical-specific. Published in the International Journal of Epidemiology in mid-March, the study, “Pesticide use and risk of non-Hodgkin lymphoid malignancies in agricultural cohorts from France, Norway and the USA: a pooled analysis from the AGRICOH consortium,” uses data from three large cohort […]

(Beyond Pesticides, February 15, 2019) A study, published in January 2019 in the journal Environmental Health, demonstrates that consumption of organic foods reduces significantly the levels of synthetic pesticide residues in the bodies of U.S. children and adults. Pesticide residues are found four times as frequently in conventionally grown food as in organically produced foodstuffs. Although the number of subjects in this study was relatively small, the results point to the importance of organics, and add to the evidence that organic food production and consumption are key to protecting human health. Study subjects comprised members of racially diverse families — from Oakland, Minneapolis, Baltimore, and Atlanta — who did not typically consume an organic diet. Study participants, ages 4 to 52, ate their typical diet of conventionally grown foods for five days; for the following six days, they switched to a certified organic diet (provided by researchers) for consumption at home, work, school, or daycare, including all foods and beverages other than water. Urine samples were gathered prior to the “organic” days, and first thing on the morning after those six days. Fourteen different pesticides and metabolites were present in all participants’ urine in the “pre-organic” analysis; following the organic diet […]

(Beyond Pesticides, October 18, 2018) Pesticide residue doesn’t announce itself –it isn’t colored, it doesn’t glow or reflect light, and after an initial application doesn’t put out a discernible odor – but it is likely ubiquitous in rural U.S. homes, according to a study published by Cornell University researchers late last month. The study is a warning specifically to households with young children, who are at increased risk of health effects from even minute levels of pesticide exposure. “Numerous health problems occur from exposure to pesticides, such as cancer, birth defects, leukemia and ocular [vision-related] toxicity, among a number of other health issues,” said Joseph Laquatra, PhD, coauthor of the research. “Households with crawling toddlers should be concerned, as toddlers will accumulate pesticide residues on their hands and then ingest them due to hand-to-mouth behaviors.” Researchers focused in on 132 households in rural counties of New York State that agreed to test for pesticide residue inside their home. Wipe samples were collected from both carpeted and non-carpeted areas, and tested for pesticides used commonly as part of agricultural production in the region. The pesticides analyzed included 15 compounds ranging from organophosphates like chlorpyrifos and malathion, to synthetic pyrethroids like resmethrin, […]

(Beyond Pesticides, June 22, 2018) Mosquito misters pose a threat to human health. They also harm bees and other flying pollinators and are the least effective way to deal with biting mosquitoes. These devices are typically placed outdoors and spray insecticides –mostly in an attempt to control mosquitoes.  In May, the Connecticut state legislature voted to ban the use of residential pesticide misting systems. Urge your Governor and state legislators to ban pesticide misters. In addition to the threat to people’s health, misters harm pollinators who may be foraging in an area where the devices are used. Studies find that sublethal concentrations of synthetic pyrethroids significantly reduce bee fecundity and decrease the rate at which bees develop to adulthood and reproduce. Field and laboratory studies using pyrethroids have consistently documented decreases in foraging activity and activity at the hive entrance after exposure. While pesticides are regulated by the U.S. Environmental Protection Agency (EPA), pesticide misters and other application devices are not subject to EPA oversight, leaving states with the authority to control their use. Connecticut appears to be the first state to restrict pesticide misting machines through legislation. The state of New York took an administrative approach to regulating these devices, as the commissioner of the […]

(Beyond Pesticides, May 23, 2018) Earlier this month, the Connecticut state legislature voted to ban the use of residential pesticide misting systems. (These are devices that are typically placed outdoors and spray insecticides –mostly in an attempt to control mosquitoes.) This is the latest move from a state legislature that has also recently banned the use of bee-toxic neonicotinoids and stopped the use of hazardous lawn care pesticides on public playgrounds. The vote was unanimous in the state Senate, and won by a count of 132-17 in the state House. The bill is set to become law on May 24, unless Governor Malloy vetoes the legislation, which is not expected. Pesticide misters are machines primarily used to spray mosquito adulticides. Many health advocates have expressed concern that these products, able to spray toxic pesticides on a timer at regular intervals, pose a significant risk to pets and children who can be directly in the path of a mister’s spray. The chemicals employed in these machines are often synthetic pyrethroids, which have been linked to a range of human health effects, from early puberty in boys, to behavioral disorders, learning problems, ADHD, and certain cancers. Neighbors who do not want to be […]

(Beyond Pesticides, February 20, 2018) The U.S. Centers for Disease Control and Prevention (CDC) finds that the U.S. Environmental Protection Agency (EPA) label restrictions on total release foggers, otherwise known as “bug bombs,” are a public health failure. Bug bombs pose a significant risk of acute illness to individuals even when they attempt to follow new label instructions. Beyond Pesticides has long called for bug bombs to be banned, as there are a myriad of non-toxic alternative strategies to successfully manage household pests. Urge your Governor to ban bug bombs in your state! Bug bombs are small cans primarily comprised of an insecticide, often a synthetic pyrethroid, a synergist such as piperonyl butoxide (PBO), and an aerosol propellant. In addition to the explosion/fire risk if the aerosol product is used in an unattended home near a pilot light or other spark-producing appliance, both synthetic pyrethroids and PBO pose acute and chronic human health risks. PBO is added to pesticide formulations to increase the toxicity of synthetic pyrethroids, and has been linked to childhood cough. Peer-reviewed research associates synthetic pyrethroids with behavioral disorders, ADHD, and delayed cognitive and motor development, and premature puberty in boys. Not only can bug bombs acutely poison, […]