(Beyond Pesticides, November 5, 2024) Published in the journal Frontiers in Toxicology, a recent study uncovers serious flaws in the pesticide registration process at the U.S. Environmental Protection Agency (EPA) with an in-depth evaluation of the agency’s failure to protect the public from the harmful effects of five neonicotinoid (neonic) insecticides—as mandated by the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) and amendments, including Food Quality Protection Act (FQPA) of 1996. This coincides with EPA’s ongoing review to renew their approval for the next 15 years (set to be announced in 2025). The report is based on the first comprehensive assessment of unpublished rodent-based Developmental Neurotoxicity (DNT) studies, conducted between 2000-2003 and submitted by pesticide manufacturers as part of the registration process. All five neonicotinoids evaluated—acetamiprid, clothianidin, imidacloprid, thiacloprid, and thiamethoxam—are associated with significant shrinkage of brain tissue at the highest dosage, according to EPA data reports (see acetamiprid, clothianidin, imidacloprid, thiacloprid, and thiamethoxam). However, with little or no data regarding the chemicals’ impacts at low and mid-level dosages, EPA has either failed to find a “No Observed Adverse Effect Level” (NOAEL) or, seemingly at random, set the NOAEL at the mid-level dosage. The evaluation suggests that perinatal exposure to […]

(Beyond Pesticides, July 23, 2024) In analyzing the interactions between neonicotinoid pesticides (NNPs) and microplastics (MPs), a recent study in The Science of The Total Environment finds that neonicotinoids such as thiacloprid (THI) become more bioavailable in soils containing traditional and biodegradable plastics. Increased bioavailability, which quantifies the extent to which organisms are exposed to chemicals in soil or sediment, puts soil microbiota at risk and leaves all consumers susceptible to adverse effects in contaminated food crops. This study raises a grave deficiency, among others, in the pesticide registration and regulatory review process, which currently ignores interactions of pesticides with other contaminants, like microplastics, in the environment when conducting health and ecological effects assessments.   The researchers, from China University of Geosciences, Beijing Academy of Agriculture & Forestry Sciences, Chinese Academy of Agricultural Sciences, and University of Swat in Pakistan, chose to study thiacloprid as an example of NNPs to explore “the adsorption-desorption process and mechanism of NNPs on MPs,” as well as the main factors affecting adsorption, since these are two contaminants of concern in agricultural environments.  Adsorption [clinging to the surface] and desorption [releasing after adsorption] of thiacloprid by both traditional and biodegradable MPs, and the impact of MPs […]

(Beyond Pesticides, June 21, 2024) A recent review of the scientific literature, published in Science of The Total Environment, analyzes multiple species of bees on a molecular level to better understand the poisoning mechanisms that could, as the authors see it, inform chemical risk assessments with more precision. The mechanisms “implicated in the tolerance of bees to specific pesticides, and thus as determinants of insecticide sensitivity, … include metabolic detoxification, insecticide target proteins, the insect cuticle and bee gut microbiota,” the authors write. This review references more than 90 studies performed over the last 30+ years, with most being published in the last 5-10 years, as the understanding and importance of molecular determinants of bee sensitivity has emerged. Pollinators, such as bees, provide crucial ecosystem services by pollinating both wild plants and essential crops. The exposure these insects are subjected to threatens their existence, which occurs through pesticide contamination that can lead to impacts on growth and development or even colony collapse.    “While bees have only been exposed to human-made pesticides over the recent past (last 80 years) they have co-evolved with plants and fungi which produce a range of xenobiotics, including plant allelochemicals and mycotoxins,” the authors state. […]

(Beyond Pesticides, September 19, 2023) Farmworkers in Paarl, South Africa took to the streets on Friday, September 8, demanding an end to the indiscriminate importation and use of pesticides, herbicides, and fungicides containing substances prohibited by the European Union (EU). This protest is part of a broader global trend of outcry against systemic issues of environmental racism that disproportionately burden communities with environmental and health risks.   Organized by the Women on Farms Project, the protesters marched to the headquarters of Bayer. The German pharmaceutical, biotechnology, and pesticide company, responsible for producing and exporting agrochemicals known to be toxic to ecosystem and human health, has previously faced multiple lawsuits, including a multimillion-dollar one linking their glyphosate weed killer products (Roundup®) to non-Hodgkin Lymphoma. At the Bayer office, the protesters presented a memorandum demanding an end to the importation and use of EU-prohibited substances.    Protesters sought to expose the hypocritical tactics European agrochemical companies use to sell products in developing nations, even when those products are deemed unsafe in their home countries. Numerous farmworkers, like victim-turned-activist Antie Dina, spoke out about their health issues from petrochemical exposure. In her talk, Dina emphasizes that, “… enough is enough, we do not want any […]

(Beyond Pesticides, January 11, 2022) Neonicotinoid insecticides can have detrimental effects on liver health, according to research published in the Journal of Hazardous Materials. While this is the first study to investigate how these chemicals harm the liver, there is increasing evidence that neonicotinoids, otherwise notorious for their effects on pollinators and aquatic life, can cause direct harm to human health. As the U.S. Environmental Protection Agency (EPA) continues to protect the pesticide industry from any measure of meaningful regulation around these hazardous products, the job falls to advocates to place pressure on elected officials to make the changes necessary to safeguard long-term health and well-being. Scientists postulated that neonicotinoids are neither metabolized by the liver nor excreted by urine. To test that hypothesis, 201 individuals from a hospital in China were enrolled into a study. Of the enrolled,  81 were cancer patients, and 120 were not. These individuals underwent a procedure called endoscopic retrograde cholangiopancreatography whereby samples of their bile, a fluid produced in the liver, were retrieved and analyzed. Researchers also performed a series of blood tests, measuring a range of biomarkers, including cholesterol, bilirubin, bile acids, white blood cells, platelets, and others. Lastly, scientists determined the amount […]

(Beyond Pesticides, January 17, 2020) In Brussels, the European Commission (EC) has just decided not to renew approval of the neonicotinoid pesticide thiacloprid, citing both environmental and health concerns related to use of and exposure to the pesticide. The decision was approved by a majority of European Union (EU) governments last fall, after the EC had made the proposal to them. The EC based that proposal on findings of the European Food Safety Authority (EFSA) published in January 2019, which highlighted concerns about toxicity to humans and high concentrations in groundwater. European Commissioner for Health and Food Safety Stella Kyriakides commented, “There are environmental concerns related to the use of this pesticide, particularly its impact on groundwater, but also related to human health, in reproductive toxicity.” The current EU use approval for thiacloprid products expires on April 30, 2020. The EC decision — functionally, a ban — means that farmers will need to turn to other means to deal with the primary thiacloprid targets in agriculture, aphids and whiteflies. Beyond Pesticides and many organic agricultural resources advocate for widespread adoption of organic, regenerative systems and practices. Such systems may include management features such as mechanical and biological controls, trap crops, natural […]

(Beyond Pesticides, March 7, 2019) A publication in the journal Environmental Health Perspectives highlights findings from a recent study showing that environmental concentrations of the neonicotinoid insecticides thiacloprid and imidacloprid increase expression of a gene linked to hormone-dependent breast cancer. Authors of the featured study uncovered a pathway through which neonicotinoids stimulate excess estrogen production, known to occur during the development of progressive hormone-dependent breast cancer. In the words of the authors, “Our findings highlight the need for further research to assess the potential impacts of low-dose and chronic exposure to neonicotinoids on endocrine processes affecting women’s health.” The study, published in Environmental Health Perspectives in April 2018 by researchers at the University of Quebec, is not the first to point to a potential link between neonicotinoid exposure and breast cancer. A 2015 study by the same research group revealed that the neonicotinoids thiacloprid and thiamethoxam, along with the herbicide atrazine, induce similar effects in breast cancer cells. In both studies, exposure to neonicotinoids alter promoter activity to induce heightened production of the enzyme aromatase, which is known to stimulate estrogen production and thereby cancer cell proliferation. The recently published study, authored by Silke Schmidt, PhD, brings greater urgency to […]

(Beyond Pesticides March 18, 2015) Fifty-two members of Congress penned a letter to the White House, calling for the protection of the Monarch butterfly, which has declined by 90 percent in the last 20 years, and for listing as a ”˜threatened’ species under the Endangered Species Act (ESA). This comes on the heels of a formal  notice  of intent to sue submitted to the U.S. Environmental Protection Agency (EPA) for failing to protect threatened and endangered species, including butterflies, amphibians and birds, from flupyradifurone, a newly approved systemic insecticide. The letter sent to President Obama on Tuesday was spearheaded by Representative Chellie Pingree (D-ME), a long-time advocate for protecting monarch butterflies. In her press release, Rep. Pingree notes that the annual migration of monarchs from North America to Mexico has plummeted because of the use of herbicides on genetically engineered (GE) crops in the U.S.   The herbicides have wiped out milkweed, the main food for monarchs.  According to the letter, efforts by farmers, local, state and federal agencies to boost habitat are laudable, but without changes in how the federal government addresses the use of herbicides, especially as applied to herbicide-resistant crops, vital monarch habitats will simply continue to […]

(Beyond Pesticides, March 16, 2015) Last week, a judge in Duesseldorf Regional Court ruled that the German branch of Friends of the Earth (BUND) has a right to speak out against chemical company giant Bayer CropScience’s neonicotinoid pesticide, thiacloprid, regarding its potential danger to bees. The court considered the allegations put forth by BUND to be a form of free speech, a protected right. Neonicotinoids, a class of insecticides, affect the central nervous system of insects, resulting in paralysis and eventual death. These pesticides have consistently been implicated as a key issue in pollinator declines, not only through immediate bee deaths, but also through sub-lethal exposure causing changes in bee reproduction, navigation and foraging. The science has become increasingly clear that pesticides, either working individually or synergistically, play a critical role in the ongoing decline of honey bees. Pesticide exposure can impair both detoxification mechanisms and immune responses, rendering bees more susceptible to viruses, parasites and other diseases, leading to devastating bee losses. Thiacloprid is one of the seven most commonly used neonicotinoids. It is used to control sucking and biting insects in cotton, rice, vegetables, pome fruit, sugar beet, potatoes and ornamentals. Low doses of neonicotinoids are considered highly […]

(Beyond Pesticides, November 5, 2014) New research from Pennsylvania State University reports that pesticides cause large changes in the expression of genes involved in detoxification, immunity and nutrition-sensing in bees, adding to previous research that has found that pesticides compromise bee immune function. This research also finds that bees with a diet of natural, high quality pollen exhibit greater resistance to pesticides’ deleterious effects than bees on an artificial diet. The new study, “Genomic analysis of the interaction between pesticide exposure and nutrition in honey bees (Apis mellifera),” finds that pesticide exposure can impact the expression of genes that are sensitive to diet and nutrition. The researchers, upon feeding honey bees either the miticidal pesticides, coumaphos or fluvalinate, for a period of seven days, noticed significant changes in 1,118 transcripts – or strands of RNA – in the experimental group. The transcripts include genes involved in detoxification, immunity, and nutrition. The authors report that there is substantial overlap in responses to pesticides and pollen-containing diets at the genetic level. Subsequent analyses demonstrate that pollen-based diets reduce the honey bees’ susceptibility to pesticide stress verses an artificial diet – e.g. a soy protein or no protein diet. Thus, the researchers note […]

(Beyond Pesticides, October 31, 2014) Without any mention of the role of pesticides in bee decline, or emphasis on organic practices to help pollinators, Agriculture Secretary Tom Vilsack announced Wednesday that more than $4 million in technical and financial assistance will be provided to help farmers and ranchers in the Midwest improve the health of honey bees. The announcement renews and expands on a $3 million pilot investment last spring to create pollinator-friendly habitat in five Midwestern states. The effort responds to the Presidential Memorandum, which directs USDA to expand the acreage and forage value in its conservation programs. The Memorandum, issued at the close of National Pollinator Week 2014, directed federal agencies to establish a Pollinator Health Task Force, and tasked agency leads at the U.S. Department of Agriculture (USDA) and U.S. Environmental Protection Agency (EPA) to develop a pollinator health strategy within 180 days that supports and fosters pollinator habitat. “The future of America’s food supply depends on honey bees, and this effort is one way USDA is helping improve the health of honey bee populations,” Vilsack said. “Significant progress has been made in understanding the factors that are associated with Colony Collapse Disorder and the overall health […]

(Beyond Pesticides, September 10, 2014) As bee and other pollinator populations continue to decline around the world, with clear evidence pointing to neonicotinoid pesticides as a prime cause, Emory University announced last week that it will be eliminating the use of this controversial class of chemicals from its campus, joining institutions and  communities like University of Vermont Law School, Spokane  (Washington),  Eugene (Oregon), and Shorewood (Minnesota). Neonicotinoids are a class of insecticides that share a common mode of action that affects the central nervous system of insects,  affecting the organisms’ ability to function. These systemic pesticides, which move through the plant’s vascular system and express themselves through pollen and nectar, include imidacloprid, acetamiprid, clothianidin, dinotefuran, nithiazine, thiacloprid and thiamethoxam. A continually growing body of science has implicated neonicotinoids, which are applied to or incorporated into seeds for agricultural, ornamental and garden plants, as a key factor in recent global bee die-offs. Beekeepers across the country reported losses of 40 to 90 percent of their bees last winter. The implications of this loss are staggering —one in every three bites of food is reliant on bee pollination, and pollinators make possible  $20-30 billion of annual U.S. agricultural production. Last week, Emory […]

(Beyond Pesticides, August 14, 2014) Pesticides are not the first thing to pop into mind when peering into a hot mug of steaming, pale green or murky black tea first thing in the morning. A recent report published by Greenpeace India announced the results of an investigation that tested for pesticide residues in branded tea. The verdict? Nearly 94% of the tea samples tested contained at least one of 34 different pesticides, while over half contained a toxic cocktail of more than 10 different pesticides. The residues found include DDT, which was banned for use in agriculture in India since 1989, and endosulfan, which was banned in 2011 by the Indian Supreme Court. Over half of the 49 samples contained illegal pesticides — either those that are not approved for use in tea cultivation or exceeded recommended limits. These pesticides include ones that have been long banned from agriculture and use in tea cultivation (DDT and triazophos), suspected mutagens and neurotoxicants (monocrotophos), and insecticides associated with the global decline in bee populations (neonicotinoids like thiacloprid and thiamethoxam). The most frequently detected pesticides include thiamethoxam (78%), cypermethrin (73%), acetamiprid (67%), thiacloprid (67%), DDT (67%), deltamethrin (67%), dicofol (61%), imidacloprid (61%), and […]

(Beyond Pesticides, August 11, 2014) Vermont Law School announced Friday that its campus is going neonicotinoid pesticide-free, making it the first higher-education campus in the country to earn official recognition from the  BEE Protective Campaign, led by Beyond Pesticides and Center for Food Safety. The university joins an expanding list of communities across the country to take action to protect pollinators in the absence of federal regulation, including Eugene, OR,   Spokane, WA, and most recently, Shorewood, Minnesota. “We are very pleased that Vermont Law School has taken the lead on going neonic-free, and hope other universities and communities will follow suit,” said Nichelle Harriott, Senior Staff Scientist at Beyond Pesticides. Neonicotinoids are a class of insecticides that share a common mode of action that affect the central nervous system of insects, resulting in paralysis and death. These systemic pesticides, which  move through the plant’s vascular system and express themselves through pollen and nectar,  include imidacloprid, acetamiprid, clothianidin, dinotefuran, nithiazine, thiacloprid and thiamethoxam. A growing body of science has implicated neonicotinoids, which are applied to or  incorporated into seeds for agricultural, ornamental  and garden plants, as a key factor in recent global bee die-offs. Beekeepers across the country reported losses […]

(Beyond Pesticides, July 25, 2014) A new U.S. Geological Survey (USGS) study published yesterday found neonicotinoid pesticides persistent and prevalent in streams throughout the Midwestern United States. The study is the first to investigate the presence of neonicotinoids on a wide-scale level in the Midwest. While neonicotinoid use has increased throughout the country, the Midwest in particular has seen a dramatic increase over the last decade. The use of clothianidin, one of the chemicals studied, on corn in Iowa alone has approximately doubled in just two years, from 2011 and 2013. Neonicotinoids are chemically similar to nicotine and are pesticides that are toxic to a broad range of insect pests. They are also known as systemic pesticides, which are pesticides that spread throughout the entire plant structure, making everything from roots to pollen toxic to organisms that come in contact with it. As a result, neonicotinoids have been linked to the global disappearance of honey bees and other nontarget organisms, such as earthworms, birds, and aquatic invertebrates. USGS scientist Kathryn Kuivila, Ph.D., stated, “Neonicotinoid insecticides are receiving increased attention by scientists as we explore the possible links between pesticides, nutrition, infectious disease, and other stress factors in the environment possibly […]

(Beyond Pesticides, June 19, 2014) The city of Spokane, Washington is inching ever closer to a ban on neonicotinoid pesticides, a class of chemicals that has been linked to the global disappearance of honey bee populations. If the ban passes, Spokane will soon be part of a growing movement to protect pollinators. The Spokane City Council will be voting on the neonicotinoid ordinance this Monday, June 23. The ban will halt both the purchase and use by the city of products that contain neonicotinoids. The ordinance specifically names six types of neonicotinoids used on crops, imidacloprid, clothianidin, thiamethoxam, dinotefuran, acetamiprid, and thiacloprid, and explains that the majority of these chemicals “are highly toxic to bees, can reduced [sic] fecundity, depress the bees immune system, and increase susceptibility to biological infections, and, depending on the amount of exposure, can be lethal/ sub-lethal to the honey bees.” You can read more about the exact wording of this proposed ordinance here. Council President Ben Stuckart, who introduced the ordinance, wants the city to stop using the chemicals on its properties. The ban would be part of an undertaking to implement environmentally sustainable initiatives at City Hall. The ordinance would affect all city departments […]

(Beyond Pesticides, June 17, 2014) Given that plant starts in many garden centers across the country are grown from seeds coated with bee-harming neonicotinoid pesticides, or drenched with them, Beyond Pesticides has launched the Pollinator-Friendly Seed Directory, a comprehensive list of companies that sell organic seeds to the general public. Included in this directory are seeds for vegetables, flowers, and herbs. As bees suffer serious declines in their populations, we urge people and communities to plant habitat that supports pollinator populations, and have provided information to facilitate this in our BEE Protective Habitat Guide, as well as our how-to guide on managing landscapes with pollinators in mind. Unfortunately, plants are too often grown with hazardous pesticides that either harm pollinators in their cultivation or threaten bees as they pollinate or forage on treated plants. Last summer, a groundbreaking report revealed that many bee-friendly garden plants sold at Home Depot and Lowe’s contain neonicotinoid pesticides with no warning to consumers. Neonicotinoid residues were detected in seven out of thirteen samples (54 percent) of commercial nursery plants. In response to this report, Beyond Pesticides, along with Friends of the Earth and other allies, launched a campaign to tell major retailers to stop […]

(Beyond Pesticides, August 16, 2013) Beyond Pesticides just helped release a new report with Friends of the Earth and other allies, revealing that the world’s most popular pesticide, neonicotinoids, implicated as a key factor in global bee die-offs, may be lurking in our own gardens. As we celebrate National Honey Bee Day this weekend, join in asking Lowe’s, Home Depot and other leading garden centers to take action and stop the sale of neonicotinoids and plants treated with these bee-killing chemicals. Take Action: Bee Protective! Tell Home Depot, Lowe’s and others to stop selling bee-killing products. There are now dozens of insecticides on retail shelves that contain neonicotinoids. Product labels show the active ingredients of these products, including: imidacloprid,  acetamiprid, clothianidin, dinotefuran, nithiazine, thiacloprid and thiamethoxam. While neonicotinoids is a relatively new class of insecticide that affects the central nervous system of insects, a growing body of science has demonstrated neonicotinoids (neonics) are a key factor in bee decline nationwide, with beekeepers recording losses of up to 90 percent of their bees this winter. Recently, 50,000 bumblebees, likely representing over 300 colonies, were found dead or dying in a shopping mall parking lot in Wilsonville, Oregon. Authorities confirmed that this […]

(Beyond Pesticides, August 15, 2013) Many “bee friendly” home garden plants sold at Home Depot (NYSE: HD), Lowe’s (NYSE: LOW) and other leading garden centers have been treated with pesticides shown to harm and kill bees, according to a pilot study released yesterday by   Friends of the Earth-US, Beyond Pesticides,  and others.  Supporting organizations sent a  letter  yesterday —along with petitions signed by more than 175,000 people— to Lowe’s, Home Depot, Target and other top garden retailers, asking the stores to stop selling neonicotinoids and plants treated with the pesticides. A majority of the UK’s largest garden retailers, including Homebase, B&Q and Wickes, have already stopped selling neonicotinoids. The pilot study, co-authored by the Pesticide Research Institute, found that 7 of 13 samples of garden plants purchased at top retailers in Washington DC, the San Francisco Bay Area and Minneapolis contain neurotoxic pesticides known as neonicotinoids that studies show harm or kill bees and other pollinators. Neonicotinoids are a relatively new class of insecticides that share a common mode of action that affect the central nervous system of insects, resulting in paralysis and death. These systemic pesticides, which  move through the plant’s vascular system and express themselves through pollen […]