(Beyond Pesticides, April 5, 2024) Exposure to chemical toxicants, molds, and algae contributes to autism and attention disorders in children, according to research that bolsters earlier findings. The exposures may be most relevant, not in the children, but one generation back—in the parents. The study, “Assessing Chemical Intolerance in Parents Predicts the Risk of Autism and ADHD in Their Children,” was published in the March issue of the Journal of Xenobiotics. Led by Claudia S. Miller, MD, an immunologist at the University of Texas at San Antonio noted for her work on chemical intolerance (CI), the authors build on previous work published in 2015 establishing parental CI as a risk factor for autism and ADHD. Dr. Miller participated in Beyond Pesticides’ 2022 Forum Series. Recordings of her presentation are available on YouTube here and here. In 1996, Dr. Miller concluded that CI is induced by Toxicant-Induced Loss of Tolerance (TILT). For further details, see Beyond Pesticides’ Daily News Blog. Three years later Dr. Miller developed the Quick Environmental Exposure and Sensitivity Inventory (QEESI), a questionnaire for individuals tracing their toxicant exposures and symptom histories. QEESI was first developed with groups exposed to organophosphate pesticides, volatile organic compounds in reconstruction and […]

(Beyond Pesticides, February 5, 2024) Public Comment Period Ends February 26, 2024. The U.S. Environmental Protection Agency (EPA) never completed protocol for testing pesticides that disrupt the fundamental functioning of organisms, including humans, causing a range of chronic adverse health effects that defy the common misconception that dose makes the poison (“a little bit won’t hurt you”)—when, in fact, minuscule doses (exposure) wreak havoc with biological systems. After a nearly two decade defiance of a federal mandate to institute pesticide registration requirements for endocrine disruptors, EPA has now opened a public comment period ending February 26, 2024 and advocates are criticizing the agency’s proposed evaluation as too narrow. A detailed examination of EPA’s proposal can be found in draft comments by Beyond Pesticides.  Endocrine disruption as a phenomenon affecting humans and other species has been critically reviewed by many authors. Endocrine disruptors are chemicals that can, even at extremely low exposure levels, disrupt normal hormonal (endocrine) function. Such endocrine disrupting compounds (EDC) include many pesticides, exposures to which have been linked to infertility and other reproductive disorders, diabetes, cardiovascular disease, obesity, and early puberty, as well as attention deficit hyperactivity disorder (ADHD), Parkinson’s, Alzheimer’s, and childhood and adult cancers. EPA […]

With the elevated adverse impacts associated with pesticides and reproductive health, the Pregnant Workers Fairness Act (PWFA) law may be used to improve protections for farmworkers and other high-risk employees.

(Beyond Pesticide, December 20, 2022) A meta-analysis published in Chemosphere finds prenatal pesticide exposure, or pesticide exposure during pregnancy has a positive association with autism spectrum disorder (ASD) and attention deficit/hyperactive disorder (ADHD). Particularly, exposure to chemical classes organophosphate (OP) and pyrethroid (PYR) insecticides, in addition to the mother’s age during pregnancy (≥30 years old), increased the risk factor of ASD. ADHD risk increases among offspring whose mothers encounter organochlorine pesticides (OCPs) during gestation. The etiology or cause of ASD and ADHD involves the interaction of multiple components, including lifestyle and genetics. However, emerging evidence indicates that environmental contaminants like pesticides (e.g., occupational exposures, air pollution, solvents, dietary residues, etc.) play a role in disease etiology. Pesticide contamination is widespread in all ecosystems, and chemical compounds can accumulate in human tissues resulting in chronic health effects.  ADHD is estimated to affect 8-12% of school-age children worldwide. While it is a complex disease, and genetics may play a role, no specific genes have been identified, and there is increasing evidence that environmental factors like pesticide exposure facilitate the development of the condition. Additionally, U.S. Centers for Disease Control and Prevention (CDC) estimates that 1 in 54 children have been diagnosed with an autism spectrum […]

(Beyond Pesticides, October 5, 2022) Exposure to widely used synthetic pyrethroids, present in many mosquito adulticides and household insecticides like RAID, is associated with a diagnosis of rheumatoid arthritis, according to research published in Environmental Science and Pollution Research. This is the latest pesticide-induced disease associated with this dangerous class of chemicals – a harm to individual Americans that the U.S. Environmental Protection Agency (EPA) is not considering when it registers pesticides. To remedy the major deficiencies in EPA’s reviews, and protect residents from chronic disease, more and more communities are transitioning to safer, organic pest management practices that do not require pyrethroids and other toxic synthetic pesticides. Rheumatoid arthritis (RA) is an autoimmune disease that causes systemic inflammation throughout the body, resulting in progressive damage to an individual’s joints. In the United States, roughly 1.3 million adults suffer from RA, accounting for nearly 1% of the adult population. Health care costs associated with the disease reach nearly $20 billion annually. To better understand the etiology behind the disease, an international team of researchers from China, Illinois, and Missouri analyzed data from the 2007-2014 National Health and Nutrition Examination Survey (NHANES), a long-running program that began in the early 1960s […]

(Beyond Pesticides, September 2, 2022) Revelations of toxic risks to pregnant people seem to emerge with alarming frequency. In late August a peer-reviewed study published in Chemosphere finds that the compound melamine, its primary byproduct (cyanuric acid), and four aromatic amines were detected in the urine of nearly all pregnant research participants. These chemicals are associated with increased risks of cancer, kidney toxicity, and/or developmental harm to the resultant child. Beyond Pesticides has covered a variety of pregnancy risks from pesticides and other toxic chemicals, including these in just the last three years: pesticides and children’s sleep disorders; prenatal exposures to a multitude of chemicals; insecticides and childhood leukemia; insecticides and Attention Deficit/Hyperactivity Disorder. Those of a certain age may hear “Melamine” and think of the nearly indestructible plastic dinnerware from the mid-20th century, but “melamine” is an organic chemical compound that, when combined with formaldehyde, forms a durable plastic. Others may remember the 2007–2008 incident in China of contamination of infant formula with melamine, which resulted in six deaths, and kidney and urinary tract harms (ranging from development of kidney stones to acute renal failure) in some 300,000 babies. [A small sidebar explainer: melamine was actually intentionally added to the formula […]

(Beyond Pesticides, September 1, 2022) Low level exposure to synthetic pyrethroid insecticides at 6-8 months of age is associated with language development delays in two-year old toddlers, according to research published in Neurotoxicology this month. This is the latest study to link this class of chemicals to developmental delays in young children. Despite a steady drum of concerning research, the U.S. Environmental Protection Agency (EPA) in 2019 removed a crucial “safety factor” intended to protect children’s health from synthetic pyrethroids, allowing higher levels of the insecticides to be sprayed on food, in homes, and playing fields around the country.   To investigate the impact of synthetic pyrethroids on language development, scientists enrolled 327 expectant mothers in their third trimester. The mothers, all from rural areas of China, were selected if they had no history of significant pesticide exposure or family history of serious disease. Urine samples were taken from the women during pregnancy, and from infants 6-8 months after birth. Scientists analyzed samples for concentrations of three different synthetic pyrethroid breakdown products (metabolites), including 3-phenoxybenzoic acid (3PBA), 4-fluoro-3-phenoxybenzoic acid (4F3PBA), and cis-2,2dibromovinyl-2,2-dimethylcyclopropane-1-carboxylic acid (DBCA). While 3PBA is a metabolite of many synthetic pyrethroids, 4F3PBA a more specific metabolite of cypermethrin, […]

(Beyond Pesticides, June 14, 2021) Beyond Pesticides reports regularly on new science showing how pesticides harm human health and ecosystems. This science is not factored into EPA decisions. Tell EPA that cutting-edge science must be considered. More than 50 pesticide active ingredients have been identified as endocrine disruptors that mimic the action of a naturally-produced hormone, such as estrogen or testosterone, thereby setting off similar chemical reactions in the body; block hormone receptors in cells, thereby preventing the action of normal hormones; or affect the synthesis, transport, metabolism and excretion of hormones, thus altering the concentrations of natural hormones. Endocrine disruptors have been linked to attention deficit hyperactivity disorder (ADHD), Parkinson’s and Alzheimer’s diseases, diabetes, cardiovascular disease, obesity, early puberty, infertility and other reproductive disorders, childhood and adult cancers, and other metabolic disorders. Similar effects are found in other species. In spite of legal requirements and the flood of research, EPA issues Proposed Interim Decisions (PIDs) on pesticide registrations making no human health or environmental safety findings associated with the potential for endocrine disruption, or identifying additional data needs to satisfy Endocrine Disruptor Screening Program requirements in the PIDs. EPA cannot make findings of no unreasonable adverse effects without findings […]

(Santa Fe, New Mexico, February 11, 2021)—New Mexico State Senator Brenda McKenna  introduced the Public Schools Pesticide Management Act (PSPMA) (SB 326) in order to protect school children from exposure to toxic pesticides where they learn and play. The legislation advances ecological pest management, an environmentally healthy way to protect children and the public from weeds and pests, within all schools, classrooms, community parks, and playgrounds in the state. Under PSPMA, only organic and minimum risk pesticides, the least toxic, yet still-effective products on the market will be allowed. Toxic pesticide use will be permitted only under a defined public health emergency, as determined by a public health official. The law does not address the use of pesticides in farming or agriculture.  “All children in New Mexico have the right to a safe environment where they learn and play,” said State Senator Brenda McKenna. “This legislation embraces an environmentally healthy approach to pest management, so families do not have to worry about the use of toxic pesticides in schools and communities.” Pesticide exposure presents unique dangers to children’s health. Children’s developing organ systems are less able to detoxify harmful chemicals, and they often come into closer contact with pesticides than adults in […]

(Beyond Pesticides, July 11, 2019) Pregnant mothers with higher concentrations of pesticide metabolites (breakdown products) in their urine are more likely to have children who develop symptoms of Attention Deficit/Hyperactivity Disorder (ADHD), according to research conducted by the University of Southern Denmark and Odense University Hospital. The results of this study are consistent with past findings from Rutgers University and Cincinnati Children’s Medical Center, indicating a need for researchers to determine causality, and pesticide regulators to rein in toxic insecticide use. The pesticides investigated by researchers were breakdown products of the organophosphate chlorpyrifos, and the synthetic pyrethroid class of insecticides. The residue of these chemicals are frequently detected on conventional, industrially farmed food products. Although chlorpyrifos is banned from residential use in the U.S., most household bug sprays such as RAID contain high amounts of synthetic pyrethroids. Among the 948 pregnant Danish women tested, 90% had some level of chlorpyrifos metabolites (3,5,6-trichloro-2-pyridinol) detected in their urine, and 94% were positive for the generic pyrethroid metabolite (3-phenoxybenzoic acid). Scientists continued to follow up with pregnant women’s children through the first five years of life. A child behavioral check list was completed to determine the relative level of ADHD symptoms. Concentrations of […]

(Beyond Pesticides, April 24, 2019) On April 19, the U.S. Court of Appeals for the 9th Circuit ordered the U.S. Environmental Protection Agency (EPA) to provide a justification for why chlorpyrifos, a neurotoxic insecticide commonly used in agriculture, should remain in the U.S. market. The EPA has 90 days to comply. Chlorpyrifos has been linked to damaging and often irreversible health outcomes in workers, pregnant women, and children. Low levels of exposure early in life can lead to increased risk of learning disabilities including lowered IQ, developmental delay, and attention deficit/hyperactivity disorder (ADHD). Farmworkers and their children are disproportionately affected by the use of this chemical because they are exposed at work, home, and even at school. “While we are moving forward, the tragedy is that children are being exposed to chlorpyrifos, a pesticide science has long shown is unsafe,” said Earthjustice Attorney Patti Goldman in a statement. “We hope Trump’s EPA finally decides to protect the future of countless children and the health of millions of farmworkers.” The battle against chlorpyrifos has been long and drawn out, though there has been significant movement in the last few months. Beyond Pesticides has put together a brief timeline of events: A […]

(Beyond Pesticides, May 3, 2018) Hawaii’s bill to ban the dangerous, neurotoxic pesticide, chlorpyrifos, passed its final hurdle this week in the state legislature. Governor David Ige is expected to readily sign SB3095 into law, in light of the unanimous support it received from lawmakers on both sides of the aisle. The statewide prohibition of chlorpyrifos will take effect beginning in January 2019. This legislative action marks the first time that any state in the country has passed an outright ban on the highly toxic organophosphate pesticide. While multiple scientific studies have determined that chlorpyrifos damages fetal brains and produces cognitive and behavioral dysfunctions, particularly in utero and in children, states have been slow to institute a complete prohibition, due to its widespread use in agriculture. Lawmakers in New Jersey and Maryland have recently tried unsuccessfully to pass similar bans. Hawaii’s bill contains a caveat that allows the state’s Department of Agriculture (DOA) to grant special permits for companies that argue that they need more time to phase-out chlorpyrifos, but that exemption will end at the close of 2022. The new law also requires restricted use pesticide (RUP) users to report to the Hawaii’s DOA which ones they are applying on […]

(Beyond Pesticides, February 20, 2018) The U.S. Centers for Disease Control and Prevention (CDC) finds that the U.S. Environmental Protection Agency (EPA) label restrictions on total release foggers, otherwise known as “bug bombs,” are a public health failure. Bug bombs pose a significant risk of acute illness to individuals even when they attempt to follow new label instructions. Beyond Pesticides has long called for bug bombs to be banned, as there are a myriad of non-toxic alternative strategies to successfully manage household pests. Urge your Governor to ban bug bombs in your state! Bug bombs are small cans primarily comprised of an insecticide, often a synthetic pyrethroid, a synergist such as piperonyl butoxide (PBO), and an aerosol propellant. In addition to the explosion/fire risk if the aerosol product is used in an unattended home near a pilot light or other spark-producing appliance, both synthetic pyrethroids and PBO pose acute and chronic human health risks. PBO is added to pesticide formulations to increase the toxicity of synthetic pyrethroids, and has been linked to childhood cough. Peer-reviewed research associates synthetic pyrethroids with behavioral disorders, ADHD, and delayed cognitive and motor development, and premature puberty in boys. Not only can bug bombs acutely poison, […]

(Beyond Pesticides, March 7, 2017) Another study, published by a team of French scientists in the journal Occupational and Environmental Medicine, links childhood behavioral problems to pyrethroid insecticide exposure. Synthetic pyrethroids are a class of insecticides that have increased in use over the past decade due to assumptions that they pose fewer risks to human health than older pesticide chemistries, such as organophosphates. However, this latest study is part of a growing body of research showing that pyrethroids share similar neurocognitive health concerns as these older pesticides. .   In this research, scientists investigate the interplay between pyrethroid exposure and behavioral problems through a longitudinal cohort study, which tracks levels of pyrethroid metabolites, or breakdown products, in the urine of mothers beginning between six and 19 gestational weeks and then in their children up through six years of age. Children’s behavior is measured through a screening questionnaire known as the Strengths and Difficulties Questionnaire (SDQ). SDQ measures how social a child is (altruism), whether the child has difficulty sharing problems or asking for help (internalizing disorders), as well as how defiant or disruptive a child is (externalizing disorders). The study controlled for a number of confounding factors, such as weight, education, location (rural or […]

(Beyond Pesticides, August 25, 2016) The County of Miami-Dade announced Tuesday that it will no longer conduct aerial sprayings on weekdays, to avoid exposing children and teachers. In an effort to control the spread of Zika, the county is consulting with the Centers for Disease Control and Prevention (CDC) and the Florida Department of Health (FDOH), to spray a neighborhood in the county, Wynwood, with Bacillus thuringiensis israelensis (Bti) and Naled. Mosquito officials were conducting the spraying during the early hours of the morning, when fewer people were around, the first day of the school year in Miami-Dade started this week, putting teachers and students at risk of exposure at bus stops. The county’s move is encouraging, because as research has continuously shown, children and pesticides don’t mix.  Studies show children’s developing organs create “early windows of great vulnerability” during which exposure to pesticides can cause great damage. Childhood pesticide exposure has been linked to a range of adverse health endpoints, including cancer, asthma, impaired sexual development, ADHD and other learning disabilities. “We have adjusted our spraying schedule to avoid any inconvenience to our local school system, and the children, families, and teachers in our community,” the office of Mayor […]

(Beyond Pesticides, August 16, 2016) Young children are disproportionately poisoned by toxic pesticides used indoors, according to a study published in the Australian and New Zealand Journal of Public Health. Data analyzed from the Queensland, Australia Poisons Information Centre (QPIC) finds that 49% of 743 insecticide-related calls in 2014 concerned young children. Given that children are more sensitive to pesticide exposure than adults because they take in more of a chemical relative to their body size and have developing organ systems, this data underscores the importance of educating the general public about alternatives to the use of toxic pesticides in and around the home. A significant share of childhood pesticide poisonings occurred in very young children. “Children in the one-year age group were at greatest risk — as they’re at that stage where they spend a lot of the time on the floor and put things in their mouth,” said Karin English, PhD candidate at the University of Queensland. As a result of children’s propensity for hand to mouth motion, cockroach baits and ant liquid were found to be the most common source of insecticide exposure for kids under five, covering 39% of calls. However, Ms. English notes that enclosing […]

(Beyond Pesticides June 4, 2015) Another study has found links between a commonly used household pesticide and attention deficit hyperactivity disorder (ADHD) in children and young teens. Researchers at Cincinnati Children’s Hospital Medical Center found an association between pyrethroid pesticide exposure and ADHD, particularly in terms of hyperactivity and impulsivity. These results reinforce the findings of a study led by a research team at Rutgers University earlier this year that found links between the pesticide deltamethrin and ADHD. In 2001, over concerns about adverse health consequences, the U.S.  Environmental Protection Agency banned several commonly used organophosphate (organic compounds containing phosphorus) pesticides from residential use due to the chemicals neurotoxic properties. The ban led to the increased use of pyrethroid pesticides, which are now the most commonly used pesticides for residential pest control and public health purposes. Pyrethroids, like deltamethrin, are commonly used in the home,  office buildings,  and on vegetable crops, gardens, lawns and golf courses. This shift to predominantly using pyrethroids is troubling, as they have oft been promoted as a safer choice than banned organophosphates, despite the fact that they pose many real threats to human health. Many recent studies show significant concern with this class of chemicals, […]

(Beyond Pesticides, March 13, 2015) Exposure to endocrine (hormone) disrupting chemicals (EDC) results in approximately € 150 billion ($162 billion) in health care costs in the European Union each year, according to panels of scientists tasked by the EU Commission to study their impact. “The shocking thing is that the major component of that cost is related to the loss of brain function in the next generation,” Philippe Grandjean, M.D. of Harvard University, one of the report’s authors, told the Guardian. EDCs, contained in common household products such as detergents, disinfectants, furniture, plastics, and pesticides, interfere with the body’s hormone system either by mimicking naturally produced hormones, blocking hormone receptors in cells, or effecting the transport, synthesis, metabolism or excretion of hormones. These impacts can result in devastating effects on one’s health, including behavioral and learning disorders, such as Attention Deficit Hyperactivity Disorder (ADHD), birth defects, obesity, early puberty, infertility, cardiovascular disease, and childhood and adult cancers. Nearly 100 percent of people have detectable amounts of EDCs in their bodies, according to the introductory guide to EDCs published by the Endocrine Society and IPEN. “Our brains need particular hormones to develop normally —the thyroid hormone and sex hormones like testosterone […]

(Beyond Pesticides, February 2, 2015) A study led by a Rutgers University research team finds that the commonly used pesticide deltamethrin increases the risk of attention deficit hyperactivity disorder (ADHD) in children, adding to a mounting body of scientific research linking pesticide exposure to the disorder. Rutgers scientists, along with colleagues from Emory University, the University of Rochester Medical Center, and Wake Forest University discovered that mice exposed to the pyrethroid insecticide deltamethrin in utero and through lactation exhibit several features of ADHD, including dysfunctional dopamine signaling in the brain, hyperactivity, working memory, attention deficits and impulsive-like behavior. The study, Developmental pesticide exposure reproduces features of attention deficit hyperactivity disorder, was published Wednesday in the Journal of the Federation of American Societies for Experimental Biology (FASEB). ADHD is estimated to affect 8—12% of school-age children worldwide. ADHD is a complex disorder, and though is strong scientific evidence that genetics play a role in susceptibility to the disorder, no specific gene has been found that causes ADHD and scientists believe that environmental factors, such as pesticide exposure, may contribute to the development of the behavioral condition. “Although we can’t change genetic susceptibility to ADHD, there may be modifiable environmental factors, including […]

(Beyond Pesticides, October 15, 2014) A new study published in Environmental Health Perspectives finds a strong relationship between the use of pesticides and depression in farmers. One specific class of pesticide, organochlorines, was associated with a 90% higher chance of being diagnosed with depression. For fumigants, the increased risk was up to 80 percent. This study echoes the conclusion from an earlier French study which also reported that farmers using pesticides face  a greater risk of developing depression. The study, Pesticide Exposure and Depression among Male Private Pesticide Applicators in the Agricultural Health Study, examines possible associations between pesticide exposure and depression among male private pesticide applicators in the Agricultural Health Study (AHS). Over 21,000 applicators who enrolled in the study in 1993—1997 were followed and examined. The applicators were asked about depression when enrolled in the study and then again around 2010. Previous work with this AHS sample found a higher prevalence of depression among male applicators who reported past pesticide poisoning or use of pesticides from several different classes. However, this study examines specific pesticides, and finds that two types of pesticides, fumigants and organochlorine insecticides are positively correlated with depression and cumulative days of use. Those exposed […]

(Beyond Pesticides, June 24, 2014) Research from the University of California, Davis CHARGE (Childhood Autism Risks from Genetics and the Environment) study finds that pregnant women who lived within a mile of agricultural fields treated with insecticides are more likely to have their child develop autism. The results of the CHARGE study, published in Environmental Health Perspectives, strengthens calls from public health and environmental groups urging regulators take a precautionary approach to agricultural chemicals and institute increased protections for those who live, work, or go to school near pesticide-treated fields. The CHARGE study looked at pregnant women’s addresses to determine their location relative to fields treated with pesticides. For women who lived less than one mile from crops sprayed with organophosphate insecticides during their pregnancy, researchers found the likelihood of their child being diagnosed with autism increased 60%. Women in the second trimester living near fields treated with chlorpyrifos, a widely used organophosphate insecticide banned for household use in 2001, are 3.3 times more likely to have their children diagnosed with autism. In response to a legal petition, the U.S. Environmental Protection Agency (EPA) in 2012 instituted risk mitigation measures for chlorpyrifos, including reduced application rates and no-spray buffer zones […]

(Beyond Pesticides, November 20, 2013) Illinois public health officials say that more than 200 Illinois schools and day care centers have failed to comply with the most basic of the state’s pest management regulations, and for the first time could face fines if they do not comply. According to the Illinois Department of Public Health (IDPH), the state’s IPM regulations, including the requirements for reporting how pests are managed, are designed to protect children in day care centers and schools from unnecessary applications of pesticides. Last Friday, the Illinois Department of Public Health announced that it is ramping up its efforts to educate day care centers and schools about the rules aimed at reducing and managing pests in light of widespread non-compliance with pest management regulations in public schools and day care centers. State law requires public schools and licensed day care centers to file an Integrated Pest Management (IPM) form with the department to document how school officials plan to implement IPM. The state’s Structural Pest Control Act (Act), [225 ILCS 235] requires public schools and licensed day care centers to, when economically feasible, develop and implement an IPM program and resubmit their plans every 5 years. Additionally, all […]

(Beyond Pesticides, November 1, 2013) Insecticides commonly used in homes and schools are associated with behavioral problems in children, according to a recent study by Canadian researchers. The study investigates exposure to pyrethroid pesticides, used in more than 3,500 products, including flea and tick controls, cockroach sprays, and head lice controls. The study, Urinary metabolites of organophosphates and pyrethroid pesticides and behavioral problems in Canadian children, published in the journal Environmental Health Perspectives, raises serious concerns about the impact of pyrethroids, which are increasingly used as a replacement for organophosphates. This study uses data from the Canadian Health Measures Survey (2007-2009), a nationally representative survey, so researchers are able to apply these findings to the entire population of Canadian children. In a previous study among U.S. children, researchers at the National Health and Nutrition Examination Survey (NHANES) examined the metabolites of pyrethroids in children below the age of six. Similarly, they found pyrethroid insecticides in more than 70 percent of the samples, concluding that children had significantly higher metabolite concentrations than those of adolescents. Together these studies demonstrate that exposure is widespread, with real impacts to human health. In the recent study, researchers analyzed organophosphate and pyrethroid metabolites in the […]