(Beyond Pesticides, March 18, 2021) A new study published in Environmental Toxicology and Pharmacology finds chronic (long-term) organophosphate (OP) pesticide exposure increases adverse health and cancer risk for U.S. women relative to men. Organophosphorus pesticides have a wide range of biological uses—from insecticides to flame retardants—that make these chemicals ubiquitous, significantly contributing to ecosystem contamination. Furthermore, while organophosphates have less bioaccumulation potential, residues are consistently present in human and animal blood, urine, tissues, and milk. Although research demonstrates that OPs are highly toxic, there remains an inadequate understanding of how OP exposure impacts the nonagricultural population in the U.S., especially women. Therefore, it is essential to investigate the sex-specific health effects chemical contaminants can produce to mitigate exposure among vulnerable populations. Study researchers note, “Given the higher burden of OP exposure and their significantly higher overall health risk, including cancer, reducing OP exposure in U.S. women needs to be prioritized.” To examine the relationship between OP exposure and health risks, researchers investigated the presence of commonly detected OP metabolite concentrations in urine using participants from the U.S. National Health and Nutrition Examination Survey (NHANES). Urine samples measure OP metabolite as an indicator of OP exposure like previous agriculture-related population surveys. Study participants report health issues […]

(Beyond Pesticides, March, 16, 2021) Occupational and environmental exposure to pesticides and other contaminants in the environment increase the risk of developing a lung condition known as idiopathic pulmonary fibrosis (IPF), according to a meta-analysis published in the journal Nature Scientific Reports. IPF is a chronic, degenerative disease with no certain cause or cure. It is estimated to affect roughly 13 women and 20 men in 100,000 adults worldwide annually, with onset averaging age 66. With scientific literature continuously findings new connections between pesticide use and diseases that are all too common in today’s world, advocates say it’s critical for residents and officials at all levels to embrace safer, alternative organic methods of addressing weed and pest issues. To determine risk factors for IPF, researchers narrowed down relevant research in the available literature from thousands of studies to eight relevant for their meta-analysis. These eight studies looked at IPF risk factors for a number of different populations with different life histories. Overall, roughly 1,000 IPF patients, ranged in ages 50 to 75, were compared to a control group of approximately 2,500 non-IPF patients. The studies covered risk factors based on the environmental contaminant in question, as well as an individual’s […]

(Beyond Pesticides, March 9, 2021) Last week, the Environmental Protection Agency (EPA) announced an interim decision to cancel of one of the most hazardous pesticides still used in the United States, pentachlorophenol (penta). Although long overdue, health advocates are hailing the agency’s action, taken due to significant risks to human health, the availability of alternatives, and the uncertain future of penta production. Many advocates hope that EPA’s announcement is the start of a pivot to science-based decision-making in the best interest of health and the environment, not the pockets of pesticide industry executives. Cancellation of this toxic chemical will bring  the U.S. into conformance with the Stockholm Convention, an international treaty to ban persistent organic pollutants (POPs) joined by over 150 countries that was never ratified by the U.S. “This has been a long time coming,” said Jay Feldman, executive director of Beyond Pesticides. “After decades of scientific reports, lawsuits, regulatory comments, and an international ban, we’re glad EPA finally acknowledged the intrinsic dangers posed by continuing penta’s registration. We urge the agency expedite its slow cancellation timeline so that we can finally eliminate this unnecessary pollutant.” Produced for its ability to preserve wood through pressure treatment, penta has been […]

(Beyond Pesticides, March 4, 2021) A new study finds glyphosate use stimulates soil erosion responsible for releasing banned, toxic pesticide chlordecone (Kepone), which was used in banana production. For years, an unknown pollution source continuously contaminated water surrounding islands in the French West Indies (Martinique and Guadeloupe). However, researchers from the University of Savoie Mont Blanc in France have found that chlordecone—extensively used on banana farms from 1972 to 1993—is the contamination culprit. Glyphosate is the most popular herbicide in the world, thus ubiquitous in the environment. Therefore, it is vital to understand the implication glyphosate use has on soil health and the potential re-release of soil-bound, toxic contaminants into the surrounding environment to safeguard human health. Researchers note, “[Chlordecone] fluxes drastically increased when glyphosate use began, leading to widespread ecosystem contamination. As glyphosate is used globally, ecotoxicological risk management strategies should consider how its application affects persistent pesticide storage in soils, transfer dynamics, and widespread contamination.” Conventional pesticide use contaminates soil and their respective Critical Zone (CZ) compartments. These CZ compartments interact between the four main spheres (i.e., hydrosphere, biosphere, lithosphere, and atmosphere) of the Earth to support life. Recent decades demonstrate an increase in soil erosion due to sediment changes […]

(Beyond Pesticides, February 25, 2021) A University of Michigan study finds a link between elevated rates of breast cancer incidents and chemical exposure from pesticides among African American women. Breast cancer is the most common cancer among women, causing the second most cancer-related deaths in the United States. However, breast cancer outcomes differ significantly among women of various races/ethnicities, with African American women being 40 percent more likely to die from breast cancer than women of any other race. Furthermore, incidences of triple-negative breast cancer (TNBC)—an aggressive breast cancer subtype lacking remediation—is approximately three-fold higher in non-Hispanic Black women (NHBW) compared to non-Hispanic White women (NHWW). Although past studies suggest genetic and environmental factors interact to produce these differences in breast cancer outcomes, genetic factors only play a minor role while disparities (differences) in external factors (i.e., chemical exposure) may play a more notable role. This study highlights the significance of understanding how chemical exposure drives disease outcomes and increases disease risk, especially for more virulent diseases that disproportionately (unequally) impact specific communities. Prior research infers differences in chemical exposure may explain racial disparities for several illnesses, and growing evidence suggests common chemical exposure patterns influence the risk of breast cancer. […]

(Beyond Pesticides, February 18, 2021) New research published in the journal Toxicological Sciences finds extended inhalation of the common herbicide paraquat causes male mice to lose some sense of smell, even at low doses. This study highlights the significance of understanding how specific chemical exposure routes can influence disease development. Olfactory (relating to the sense of smell) impairment is a precursory feature of Parkinson’s disease (PD), and studies connect paraquat poisoning to PD risk. Hence, future pesticide management policies should assess specific disease risks with bodily chemical concentration from low-dose, chronic neurotoxic chemical exposure. The study’s researchers note, “These data support the importance of route of exposure in the determination of safety estimates for neurotoxic pesticides, such as [paraquat]. Accurate estimation of the relationship between exposure and internal dose is critical for risk assessment and public health protection.” Despite evidence demonstrating that olfactory  nerve cells transport toxic airborne particles and solutes to the brain upon inhalation, the possibility of olfactory impairment (damage) from paraquat inhalation lacks adequate assessment. To assess the impact paraquat has on olfactory function, researchers exposed a cohort of adult female and male mice to paraquat aerosols in an inhalation chamber for four hours a day, five days a week, for four weeks. Researchers investigated paraquat concentrations […]

(Santa Fe, New Mexico, February 11, 2021)—New Mexico State Senator Brenda McKenna  introduced the Public Schools Pesticide Management Act (PSPMA) (SB 326) in order to protect school children from exposure to toxic pesticides where they learn and play. The legislation advances ecological pest management, an environmentally healthy way to protect children and the public from weeds and pests, within all schools, classrooms, community parks, and playgrounds in the state. Under PSPMA, only organic and minimum risk pesticides, the least toxic, yet still-effective products on the market will be allowed. Toxic pesticide use will be permitted only under a defined public health emergency, as determined by a public health official. The law does not address the use of pesticides in farming or agriculture.  “All children in New Mexico have the right to a safe environment where they learn and play,” said State Senator Brenda McKenna. “This legislation embraces an environmentally healthy approach to pest management, so families do not have to worry about the use of toxic pesticides in schools and communities.” Pesticide exposure presents unique dangers to children’s health. Children’s developing organ systems are less able to detoxify harmful chemicals, and they often come into closer contact with pesticides than adults in […]

(Beyond Pesticides, February 11, 2021) California sea lions (Zalophus californianus) are experiencing high rates of urogenital carcinoma (UGC) cancer incidences from the combined effect of toxic “legacy” pesticides like DDT and the viral infection Otarine herpesvirus-1 (OtHV1), according to a new study published in Frontiers in Marine Science. Previous research documents the role herpesvirus infection, genotype, and organochlorine pesticides play in sea lion cancer development. However, synergism (collaboration) between viral infection and toxic chemical exposure increases cancer development odds. Pollution of the oceans with toxic chemicals lacks adequate regulation, is widespread and only getting worse. More than 80 percent of ocean pollution comes from land-based, anthropological activities. A recent study published in Annals of Public Health finds toxic chemicals from pesticides, heavy metals, plastics, and other sources readily contaminate the ocean, especially near coastal regions where chemical inputs occur in higher concentrations. Globally, pollution has major disease implications, causing the deaths of over nine million people annually. Therefore, it is essential to understand the co-effects of ocean pollution and diseases to protect human health. Authors of the study state, “This study has implications for human health, as virally associated cancer occurs in humans, and likelihood of cancer development could similarly be increased by exposure to environmental […]

(Beyond Pesticides, February 9, 2021) Multinational agrichemical corporation Bayer/Monsanto released a proposal last week to provide up to $200,000 per claimant in compensation to future victims of its Roundup weed killer, according to Reuters. The proposed settlement, agreed to with lawyers representing victims, continues Bayer/Monsanto’s attempts to limit the spiraling cost Roundup lawsuits, which have awarded individual victims millions of dollars in damages. The company appears to consider the proposal a good investment, as it has announced no plans to stop sale and production of its carcinogenic weed killer. However, under the current proposal, plaintiffs would not be forced to go through a compensation fund, and could seek additional punitive damages through a separate suit. As the attorney for Roundup victims, Elizabeth Casbraser, of Lieff Cabraser Heimann & Bernstein, told the Wall Street Journal, “It’s really about options, and it’s really about choice. I think it’s a great option that offers predictability and transparency for people who don’t want to wait, who want to be compensated.” To stop the surge of cancer victims – comprising roughly 125,000 lawsuits – from further damaging the company financially, Bayer/Monsanto last year proposed a $10.9 billion settlement with current litigants. Unresolved future claims were […]

(Beyond Pesticides, February 4, 2021) A review published in Food and Chemical Toxicology suggests organophosphorus pesticides (OPs) may increase the ability of SARS-CoV-2 to cause COVID-19, especially among vulnerable individuals with underlying medical conditions. Organophosphorus pesticides have a wide range of biological uses that makes these chemicals ubiquitous, significantly contaminating both terrestrial (land) and aquatic (water) environments. However, OPs are highly toxic, originating from the same compounds as World War II nerve agents. Moreover, OPs are one of the leading causes of poisoning globally. Therefore, it is vital to understand how OPs exposure will impact human health in conjunction with other immunologically compromising diseases like COVID-19. Considering COVID-19 and OP exposure act similarly on the respiratory system, exacerbating adverse inflammatory responses, reviews like these highlight the significance of evaluating synergism between diseases and toxic chemicals to safeguard human health. Researchers in the study note, “To curb SARS-CoV-2 infection, a healthy immune system is obligatory despite potent vaccine to alleviate morbidities in patients. But unintentional exposure to OP compounds from several sources can rupture the antiviral defense against SARS-CoV-2. Moreover, respiratory ailments may also be fueled by OP compounds. Hence, SARS-CoV-2 mediated morbidities and fatalities could be backed by unintentional exposure to OPs in […]

(Beyond Pesticides, January 22, 2021) After the past four devastating years, hopes and expectations of the Biden/Harris administration abound among the environmental and public health communities. The ears and eyes of many advocates, as well as those in the agricultural community, are attuned (among myriad candidates) to the fate of the pesticide aldicarb. Although Environmental Protection Agency (EPA) registration of this terribly toxic insecticide was cancelled in 2010, various limited-use reapprovals since then have meant that the compound has found its way to increasing levels of use. On January 12, as another parting shot of midnight rulemaking, Trump’s EPA approved expanded uses (see below). The $64,000 question is whether the new administration will use its authority under the Congressional Review Act — which enables Congress to pass a joint resolution (then signed by the President) to overturn a new federal agency rule and prevent its reissuance in the future — to get this pesticide retired for good. Beyond Pesticides urges President Biden’s EPA to do so. Notably, the Trump administration used the Congressional Review Act to destroy myriad environmental rules when it came into power. This permitting of expanded aldicarb uses fits the pattern. Environmental Health News notes that, as of early […]

(Beyond Pesticides, January 21, 2021) A new Swedish study in Environmental Health Perspectives demonstrates individuals with genetically weakened skin barrier protection experience higher rates of toxic chemicals (i.e., pesticides) absorption through the skin. Studies provide evidence that filaggrin genetic mutations can exacerbate the impacts of chemicals upon dermal (skin) exposure, causing various skin diseases like dermatitis and other chemical-related effects like asthma and cancer. Filaggrin is a protein that is critical to skin cell structure or epidermal homeostasis. Just as excessive exposure to UV light can cause skin discoloration and cancer, excessive dermal contact with these toxic chemicals can cause a range of adverse reactions, including dermatitis, allergic sensitization, and cancer. Dermal exposure is the most common pesticide exposure routes, compromising 95 percent of all pesticide exposure incidents. Furthermore, many pesticides contain chemicals that act as sensitizers (allergens). Therefore, it is essential to mitigate direct skin contact with these toxic chemicals and enforce proper application protocol. Dermal chemical exposure is an increasing concern for occupational (work-related) health. Likewise, people experience dermal exposure to chemicals from everyday products like cleaning supplies, personal care products, agricultural chemicals, fabrics, non-stick cookware, and general airborne pollution. Furthermore, skin disease risks can increase among those with less protection from chemical exposure due to genetics. The study’s […]

(Beyond Pesticide, January 14, 2021) Long-term exposure to permethrin and legacy organochlorine pesticides (aldrin, dieldrin, and lindane) increase the risk of developing monoclonal gammopathy of undetermined significance (MGUS), a blood disease that likely precedes multiple myeloma (MM)—a type of blood cancer, according to research in the journal Environmental Health Perspectives. Globally, cancer is one of the leading causes of death, with over eight million people succumbing to the disease every year. Notably, the International Agency for Cancer Research (IARC) predicts new cancer cases to rise by 67.4% in 2030. Although there is a vast amalgamation of research linking cancer risk to genetic and external factors (e.g., cigarette smoke), there is increasing evidence that pesticide exposure augments the risk of developing both common and rare cancers, including MM. This study highlights the importance of understanding how pesticide use can increase the risk of latent diseases, which do not readily develop upon initial exposure. Study researchers state, “Our findings provide important insights regarding exposures to specific pesticides that may contribute to the excess of MM among farmers… [T]he continued widespread residential and other use of permethrin and environmental exposure to organochlorine insecticides due to legacy contamination…could have important public health implications for exposed individuals in the general population.” […]

(Beyond Pesticides, December 22, 2020) Opening arguments and evidence were filed by a coalition of farmworkers, farmers, and conservationists last week in litigation challenging the U.S. Environmental Protection Agency’s (EPA) re-approval of glyphosate, best known as the active ingredient in Monsanto’s “Roundup” pesticides. The lawsuit charges that the Trump Administration unlawfully ignored cancer risks and ecological damage of glyphosate.  Represented by the Center for Food Safety (CFS), plaintiffs, including the Rural Coalition, Farmworker Association of Florida, Organización en California de Lideres Campesinas, and Beyond Pesticides, filed the federal lawsuit in the Ninth Circuit Court of Appeals in March. The groups seek to have the pesticide prohibited from use or sale because of its unlawful approval. “Farmworkers are on the frontlines of nearly every health and environmental crisis, from the COVID-19 pandemic to climate change, and are particularly at risk of health impacts from pesticide spraying,” said Amy van Saun, senior attorney at CFS. “EPA failed these essential workers. It rejected evidence that glyphosate causes cancer and entirely failed to assess the main way people are exposed at work, through their skin.” The court filing includes volumes of evidence showing how EPA ignored glyphosate’s health risks, including cancer risks, to farmworkers and farmers exposed during spraying. The evidence […]

(Beyond Pesticides, November 26, 2020) With the coronavirus pandemic raging across the United States, this Thanksgiving will be like no other in recent memory. Although many will spend dinner away from friends and family, and video calls don’t quite match time around the table, there is still so much to give thanks for. This year, we at Beyond Pesticides are honoring the essential, frontline workers that have helped us through this difficult year.   It is not enough to simply gives thanks to health care, transportation, retail, hospitality, custodial, teachers, farmworkers, landscapers, and other frontline workers putting themselves at risk. We must take action to improve their conditions – particularly when it comes to exposure to toxic chemicals that exacerbate underlying conditions and increase susceptibility to Covid-19. This 2020 Thanksgiving, give thanks but also show thanks by taking action. Give Thanks to Health Care Workers. Health care workers are past overstressed. Many are at the point of complete burnout. Already subject to multiple medical and personal demands, many health care workers continue to lack proper equipment, are understaffed, and at greatest risk of contracting Covid-19. Show Thanks: The best action to take to thank essential health care workers, oddly enough, […]

(Beyond Pesticides, November 25, 2020) New research from the Centre for Environment and Occupational Health Research at the University of Cape Town (UCT), South Africa, finds a link between pesticide exposure and adverse neurological symptoms among children and adolescents living in agricultural areas. Considering the etiology (cause) of many brain and neurological disorders are unknown, research like this is significant for understanding how pesticide exposure promotes disease development, especially among vulnerable populations. Researcher notes, “Children who indicate activities related to pesticide exposure may be at higher risk for developing headaches and lower cognitive performance in the domains of attention, memory and processing speed. […]Given [the] history and socio-economic divide to the farm laborers, […]future interventions should aim to reduce the health risks of these vulnerable populations, including their children.” The study demonstrates that there is a relationship between pesticide exposure from various farm-related and leisure activities and headaches and neurocognitive functioning (i.e., autism, attention deficit hyperactivity disorder (ADHD), lower intelligence (IQ), and harmful social behavior and behavioral regulation) in children and adolescents. To assess which farm-related/leisure activities concerning pesticide exposure cause cognitive symptoms, researchers administered a questionnaire addressing child pesticide handling, direct consumption of field crops, interaction with field adjacent water sources, […]

(Beyond Pesticides, November 24, 2020) Reinforcing a body of scientific evidence, a new study finds that eating organic food lowers one’s risk of developing type 2 diabetes. With 1 in 10 (34 million) Americans afflicted with type 2 diabetes, and 1 in 3 (88 million) with prediabetes, new strategies focused on prevention are urgently needed. The results of the study, published by a team of French and American researchers in the International Journal of Behavioral Nutrition and Physical Activity, reinforce the triple bottom line (profit, people, and the environment) benefits of organic food for public health, the environment, and the wider economy. Scientists used data from NutriNet-Santé, a massive study including over 170,000 participants (averaging 52 years old) that regularly respond to questions concerning lifestyle, dietary intake, body type, physical activity, and health status. Roughly 33,000 NutriNet-Santé participants completed food frequency questionnaire regarding how often they consumed organic food. After four years, 293 surveyed individuals had been diagnosed with type 2 diabetes. Researchers then looked at how organic food consumption affected the risk of developing the disease, adjusting for body mass index, gender, family history of diabetes, physical activity, education, economic status, occupation, smoking, and alcohol consumption. Higher organic food […]

(Beyond Pesticides, November 5, 2020) Research at the University of California San Francisco (UCSF) finds that pesticide exposure increases the risk of developing Parkinson’s disease (PD), regardless of whether disease onset is idiopathic (spontaneous) or genetic (GBA genetic risk variant). Although the exact etiology of PD remains unknown, epidemiological and toxicological research repeatedly identifies exposure to pesticides, as well as specific gene-pesticide interactions, as significant adverse risk factors that contribute to PD. Furthermore, this study, “Gene Variants May Affect PD Risk After Pesticide Exposure,” suggests that environmental triggers like occupational exposure to pesticides can prompt PD in individuals with or without the genetic precursor. This research demonstrates the importance of assessing disease etiology concerning occupational pesticide exposure, especially if disease triggers are overwhelmingly non-hereditary. Since not all individuals genetically predisposed to the disease develop PD, with only 10 to 15 percent of PD cases being genetic, government officials need to consider alternate etiological pathways that include environmental risk factors. Study researchers note, “‘Environmental exposures may have differential effects in different genotypes’ and may predispose people with PD to different symptom burden.”  Parkinson’s disease is the second most common neurodegenerative disease, with at least one million Americans living with PD and about […]

(Beyond Pesticides, October 22, 2020) Prolonged dermal (skin) exposure to hazardous disinfectants, via handling and/or residue on surfaces, can induce the risk of adverse skin reactions (i.e., inflammation, burns, necrosis), according to a novel review analysis published in Clinics in Dermatology. Researchers of the review, “Dermatologic reactions to disinfectant use during the COVID-19 pandemic,” examine skin reactions associated with dermal exposure to various disinfectants approved for use against COVID-19 by the European Chemical Agency (ECA) and the U.S. Environmental Protection Agency (EPA). The Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) classifies disinfectants as pesticides, so it is up to the states to delegate training, registration, and enforcement. Many states enforce pesticide training that allows professional applicators to learn how to handle, apply, and store pesticides properly. However, many of these same states do not have professional training for disinfectant use, especially wide-scale applications. Consequently, disinfectant applications are now more pervasive than ever, especially as school reopenings ensues. Considering failure to “Comply with Labeling and Permit Conditions” was the most common pesticide use violation of 2018, according to the California Department of Pesticide Regulations (DPR), advocates are urging global leaders to recognize the potential impacts that frivolous disinfectant use can have on […]

(Beyond Pesticides, October 15, 2020) A review of scientific literature on the correlation between respiratory diseases and pesticides exposure—published in the journal Annals of Agricultural and Environmental Medicine (AAEM), “Influence of pesticides on respiratory pathology—a literature review”—finds that exposure to pesticides increases incidents of respiratory pathologies (i.e., asthma, lung cancer, and chronic obstructive pulmonary disease [COPD]—or chronic bronchitis). The review by researchers at the Iuliu Hatieganu’ University of Medicine and Pharmacy Cluj-Napoca, Cluj-Napoca, Romania, looks at how pesticide exposure adversely propagates and reinforces respiratory diseases in humans. This review highlights the significance of evaluating how pesticide exposure impacts respiratory function, especially since contact with pesticides can happen at any point in the production, transportation preparation, or application treatment process. Researchers in the study note, “Knowing and recognizing these respiratory health problems of farmers and their families, and also of [pesticide] manipulators/retailers, are essential for early diagnosis, appropriate treatment, and preventive measures.” This study results are critically important at a time when exposure to respiratory toxicants increases vulnerability to Covid-19, which attacks the respiratory system, among other organic systems. The respiratory system is essential to human survival, regulating gas exchange (oxygen-carbon dioxide) in the body to balance acid and base tissue cells for normal […]

(Beyond Pesticides, October 14, 2020) Exposure to certain endocrine disrupting pesticides increases the risk men, and Hispanic men in particular, will contract testicular cancer, according to research presented at the American Association for Cancer Research Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved. The data show that living near the use of the insecticide acephate presents the greatest cancer risk. “Testicular cancer rates have been rising for decades and are rising especially quickly among Hispanics in the United States,” said Scott Swartz, an MD candidate in University of California Berkeley-UCSF Joint Medical Program, to Healio. “Given that Hispanics are disproportionately exposed to many endocrine-disrupting pesticides in California, we were interested in investigating the potential effects of nearby endocrine-disrupting pesticide application on testicular cancer among Hispanics in California.” Using public health databases, researchers assessed a group of 381 men diagnosed with testicular cancer while 15 to 19 years old, during the years 1997-2011. This cohort was compared to a control group of 762 otherwise healthy men of similar age, race and ethnicity during the same time. California’s Pesticide Use Report system was used to analyze agricultural pesticide applications within 1.8 miles of a study […]

(Beyond Pesticides, October 8, 2020) Research from the University of Wisconsin—Madison (UWM), suggests that fludioxonil—a commonly used agricultural fungicide—decreases the human body’s ability to defend itself against illnesses, like COVID-19, and promotes disease permanency. Tristan Brandhorst, a Ph.D. scientist at UWM, notes that a pesticide-induced reduction in the antioxidant glutathione could be responsible for this lack of bodily defense against disease. Although many studies examine how pesticides adversely affect the human body (i.e., cancer, respiratory issues, etc.), very few studies assess how pesticides reinforce chemical disruption patterns that reduce levels of vital chemicals needed for normal bodily function. The steady rise in U.S. pesticide use, including disinfectants, threatens animals and humans, as exposure to indiscriminate dispersal of pesticides cause a whirlwind of health risks. As the total U.S. COVID-19 cases rise above 7.5 million, global leaders need to understand extensive pesticide spraying is not a viable solution to prevent illness and causes more chronic harm from exposure in the long run. Dr. Brandhorst stresses the need for proper reevaluation of pesticide risks stating, “The issue needs more study, [and] might also warrant a reworking of how [the U.S. Environmental Protection Agency] evaluates pesticides.” Amidst the outbreak of SARS-CoV-2 (COVID-19), the global demand […]

(Beyond Pesticides, September 30, 2020) Low doses of neonicotinoid (neonic) insecticides are known to disrupt insect learning and behavior, but new science is providing a better understanding of how these effects manifest at a cellular level. Published in the Proceedings of the National Academy of Sciences, this study finds that the neonic imidacloprid binds to brain receptors, triggering oxidative stress, reducing energy levels, and causing neurodegeneration. “Although many studies have shown that low doses of insecticides can affect insect behavior, they have not uncovered whether insecticides trigger changes at the cellular and molecular levels,” said lead author Felipe Martelli, PhD, of Monash University in Melbourne, Australia. “The goal of this work was to have a better understanding of the effects of low doses of the common insecticide imidacloprid at the cellular, physiological and behavioral levels.” Researchers used the fruit fly Drosophilia melanogaster, a common experimental organism, as it contains a number of nicotinic acetylchloline receptors, the primary site of action for imidaclorpid. The neonic binds to these receptors, which regulate a number of physiological processes, such muscle contraction. Binding closes these channels, leading to the range of harm researchers observed through their study. Larval fuit flies were exposed to imidacloprid […]