(Beyond Pesticides, March 13, 2014) Part deux of a 2012 study finding that sperm counts in French men had decreased 30% over the past 16 years came to a second startling conclusion in a 2014 analysis: the cause for those dramatic decreases may be pesticides. 2012 Sperm-Count Study Published in the scientific journal Human Reproduction, the landmark 2012 study showed an alarming 30 percent decrease in sperm counts across France between 1989 and 2005. Because the data for the 2012 study were drawn from Fivnat ””a French assisted reproduction technology database”” researches made sure to limit analysis to 26,600 sperm samples from otherwise virile 35-year-old men whose partners’ fallopian tubes were either blocked or missing. This control was added to ensure that the each couple’s infertility was due to these latter problems and not a problem with the man’s sperm. Broken down, the 2012 studies identified a 1.9 percent continued annual dip in sperm concentration and also found that there was a significant 33.4% decrease in the percentage of normally formed sperm over the entire 16-year period. At the time of release, the 2012 study’s authors wrote: “To our knowledge, it is the first study concluding a severe and general […]

(Beyond Pesticides, March 10, 2014)  Virtually all lice in the U.S. have developed resistance to over-the-counter and prescription shampoos containing the toxic chemical permethrin. The U.S. Environmental Protection Agency’s Office of Pesticide Programs  considers permethrin, part of the synthetic pyrethroid class of chemicals, “likely to be carcinogenic.” However, when used as a lice shampoo the chemical is regulated by the Food and Drug Administration and allowed for use on infants over two months old. The latest study on lice resistance, published in the Journal of the Entomological Society of America, shows that harsh chemical treatments not only are not necessary given effective least-toxic alternatives, but also are not able to provide the lice control that manufacturers claim. “In the UK and Europe, they don’t even use pyrethroids anymore. Virtually everyone but the United States and Canada has given up using these over-the-counter products,” said Dr. John Clark, PhD, a professor of environmental toxicology and chemistry at the University of Massachusetts Amherst and co-author of the new study. In an interview with the Detroit Free Press,  Eric Ayers, MD of the Children’s Hospital of Michigan noted that lice that are not killed by the chemical treatment not only survive, but become […]

(Beyond Pesticides, February 25, 2014) During the Vietnam War, over 10 million pounds of the toxic herbicide Agent Orange were applied from military aircraft to defoliate forests and destroy civilian crops. Outfitted with spraying equipment, UC-123 transport planes played a major role in the American military’s campaign to eliminate forest cover for Vietcong fighters. After the war, these aircraft were returned to use in the United States for basic transport operations such as cargo shipping and medical evacuation missions. However, these planes never underwent any form of decontamination or testing before being repurposed for use back in the states. Although the U.S. Air Force and Department of Veteran Affairs have asserted that “dried residues” on these aircraft were not likely to pose a health threat to aircraft crew – a justification used to deny sickened veterans medical support, a new study from the journal Environmental Research finds strong evidence of health risks from residual exposure. The study, Post-Vietnam military herbicide exposures in UC-123 Agent Orange spray aircraft, modeled flight crew’s potential exposure to dioxin, a contaminant in Agent Orange and a  highly potent carcinogen. Scientists based their models on monitoring tests that found dioxin contamination in the mid-1990’s and late […]

(Beyond Pesticides, February 19, 2014) Over 30 environmental and consumer groups in New York are protesting new language in the state’s proposed budget that strips away the requirement that commercial pesticide applicators report where pesticides are used, what kind of pesticides they use and how much. The new reporting regulation will require that sales are recorded at the register, instead of where they are applied, eroding the public’s right-to-know. The law has allowed the public access to summary pesticide  use information at the zip code level, and granted researchers access to confidential pesticide use for analysis. However, the proposed rules, written into the state’s Executive Budget proposal, dramatically restructures the state’s Pesticide Sales and Use Reporting Law, stipulating that the annual pesticide reporting summary release detailed sales – not use – data by county. Opponents of the change say that where things are sold are not necessarily where they are used. The inability to  identify where pesticides are used in the state will undercut the ability to track  associated environmental and health effects. “It will impede the public’s ability to learn about toxic chemical uses where they work, live and play,” said Peter Iwanowicz, executive director of Environmental Advocates of […]

(Beyond Pesticides, February 5, 2014) According to a new study published in Environmental Health Perspectives, chemical contaminants in waterways that mimic estrogen -endocrine disruptors- target developing heart valves in fish and impair the growth of fish hearts. The study illustrates that these hormone-mimicking compounds, which include some pesticides, pharmaceuticals, and other household chemicals often found in sewage effluent and runoff that flows into waterways, are being linked to mounting science that show serious human and environmental adverse effects. Researchers from the Fish Health Branch of the U.S. Geological Survey (USGS) and the Carnegie Institution for Science exposed zebrafish embryos to water from 19 sites in the Susquehanna, Delaware, Allegheny and Shenandoah watersheds. Water from 16 of the sites triggered proteins in the fish that were estrogen receptors, indicating that the rivers contained endocrine disrupting chemicals. These receptors are attached to DNA, which turn genes on and off. While such activity is common in the liver, this is the first experiment to show estrogenic activity in heart valves. “This tells us that endocrine-disrupting chemicals could lead to improper heart development. We were quite surprised, since this is something that others hadn’t observed before,” said study co-author Luke Iwanowicz, PhD, and research […]

(Beyond Pesticides, January 31, 2014) Michael Skinner, Ph.D.,  author of the landmark study that links exposure to the insecticide DDT with multi-generational effects, ultimately contributing to obesity three generations down the line, is joining an impressive array of speakers at Beyond Pesticides’ 32nd National Pesticide Forum, April 11-12 in Portland, Oregon. Dr. Skinner’s groundbreaking research on transgenerational effects of pesticides has created quite a stir within the scientific community and backlash from the industry. A professor in the School of Biological Sciences at Washington State University, Dr. Skinner has published over 240 peer-reviewed publications and has given over 237 invited symposia, plenary lectures and university seminars. His  research focuses on the investigation of gonadal growth and differentiation, with emphasis in the area of reproductive biology. His current research has demonstrated the ability of environmental toxicants to promote the epigenetic transgenerational inheritance of disease phenotypes due to abnormal germ line epigenetic programming in gonadal development. Science Magazine has dubbed Dr. Skinner “The Epigenetics Heretic.” The article, published January 24, explores the controversy surrounding his recent findings, industry challenges to his research,  as well as the significance: “To those who don’t flatly dismiss Skinner’s findings, he has raised a tantalizing glimpse of […]

(Beyond Pesticides, January 29, 2014) People with high levels of exposure to the banned insecticide DDT are four times more likely to have Alzheimer’s disease than people with low levels, according to a new study of patients in Georgia and Texas. The research is among the first to report a connection between Alzheimer’s disease, which is the world’s most common neurodegenerative disease, and chemicals in the environment. The traces of the insecticide found in the study’s Alzheimer’s patients are comparable to the amounts found in most Americans today. Although it was banned more than 40 years ago in the U.S., DDT still persists in the environment worldwide and is still used today in developing countries for malaria abatement programs. “Our findings suggest that genetically susceptible individuals with higher levels of DDT exposure may be more at risk,” said Jason Richardson, PhD, a Rutgers University researcher who led the study. The case-control study consisting of existing samples from patients with Alzheimer’s disease and control participants from the Emory University Alzheimer’s Disease Research Center and the University of Texas Southwestern Medical School’s Alzheimer’s Disease Center measured serum levels of DDE in 79 control and 86 Alzheimer’s disease cases. Levels of DDE, a […]

(Beyond Pesticides, December 20, 2013) The European Food Safety Authority (EFSA) announced on Tuesday that pesticides linked to honey bee deaths worldwide may also damage human nervous systems ””in particular the brain, and recommended that the European Commission lower the guidance levels of acceptable exposure until more research is conducted. This new determination heightens the call to ban the use of these toxic chemicals in the U.S., following the lead of the European Union (EU). EFSA found that two commonly used chemicals “may adversely affect the development of neurons and brain structure associated with functions such as learning and memory” particularly of children. The recommendation focuses on two chemicals ””acetamiprid and imidacloprid”” in a relatively new class of insecticide called neonicotinoids. Three chemicals in this class were recently placed under a two-year ban in the European Union (EU) for uses on flowering crops known to attract honey bees. The move stems from a recent review of research on rats which found, “Neonicotinoids may adversely affect human health, especially the developing brain.” Researchers who exposed newborn rats to one of these chemicals ””imidacloprid”” found they suffered brain shrinkage, fewer nerve signals controlling movement, and weight loss. Another study on rats found […]

(Beyond Pesticides, December 12, 2013) Milk lovers everywhere may feel a little less guilty the next time they indulge in that usually taboo glass of creamy, whole milk ””as long as it is organic, that is. A new study, Organic Production Enhances Milk Nutritional Quality by Shifting Fatty Acid Composition: A United States—Wide, 18-Month Study, conducted by Charles M. Benbrook, Ph.D.  and other researchers from Washington State University found that organically produced milk provides significantly more heart-healthy omega-3 fatty acids than conventionally produced milk. The study looked at 384 samples of organic and conventional milk from across the country spanning an 18-month period of time (between 2011 and 2012) and examined the breakdown of omega-6 fatty acids as compared to omega-3 fatty acids within each sample. The results show that although the total amount of fat was almost the same, the organic milk contained 62 percent more omega-3 fatty acids and 25 percent fewer omega-6s. Omega-3 fatty acids are needed for healthy blood-clotting function and brain cell development and performance, among other essential bodily functions. Studies have linked omega-3 consumption to decreased risks of heart disease and other conditions, including cancers and Alzheimer’s. Omega-6 fatty acids are also necessary and […]

(Beyond Pesticides, December 10, 2013) A former steward for Australian-based Quantas airlines is suing the Australian government claiming that frequent insecticide use in airplane cabins resulted in his Parkinson’s disease diagnosis. Australia is among 49 countries that require pesticide spraying on some or all flights. Pesticide use on flights into the United States is not required, but is permitted under international law. (See here for a breakdown of pesticide use in American-based airlines, and here for information from the U.S. Department of Transportation on pesticide use in aircrafts.) Brett Vollus, former Quantas airline steward, worked for the company for 27 years until this past May when he was diagnosed with Parkinson’s and a malignant brain tumor. “He [my doctor] asked me what I did for living and when I told him he just nodded and said: ‘Another one, I am seeing a lot of you’,” Mr. Vollus said to The Australian. “This is a nightmare that has ruined my life. I am very keen to start a legal action and if it can help others I am happy to lead the way.” This case puts an international spotlight on growing evidence that pesticide use is linked to Parkinson’s disease. Parkinson’s […]

(Beyond Pesticides, December 6, 2013) In a new study exploring gene-environment interactions, researchers find that individuals with a genetic mutation linked to Parkinson’s disease are more likely to develop the neurodegenerative disease if they are exposed to pesticides. The study, Isogenic Human iPSC Parkinson’s Model Shows Nitrosative Stress-Induced Dysfunction in MEF 2-PGC1α Transcription, identifies the molecule that protects neurons from pesticides, ties genetic mutation to pesticide exposure, and demonstrates that low dose exposure can cause Parkinson’s disease. The study, conducted by researchers at the Massachusetts Institute of Technology and the Sanford-Burnham Medical Research Institute in La Jolla, CA, supports previous epidemiological and animal studies that demonstrate the link between pesticide exposure and neurological damage, using human stem cells as a model. “For the first time, we have used human stem cells derived from Parkinson’s disease patients to show that a genetic mutation combined with exposure to pesticides creates a ‘double hit’ scenario, producing free radicals in neurons that disable specific molecular pathways that cause nerve-cell death,” says lead author Stuart Lipton, M.D., Ph.D., professor and director at the Sanford-Burnham’s Medical Research Institute. Using skin cells from Parkinson’s patient who already possess the genetic mutation linked to the disease, researchers transformed […]

(Beyond Pesticides, November 20, 2013) Illinois public health officials say that more than 200 Illinois schools and day care centers have failed to comply with the most basic of the state’s pest management regulations, and for the first time could face fines if they do not comply. According to the Illinois Department of Public Health (IDPH), the state’s IPM regulations, including the requirements for reporting how pests are managed, are designed to protect children in day care centers and schools from unnecessary applications of pesticides. Last Friday, the Illinois Department of Public Health announced that it is ramping up its efforts to educate day care centers and schools about the rules aimed at reducing and managing pests in light of widespread non-compliance with pest management regulations in public schools and day care centers. State law requires public schools and licensed day care centers to file an Integrated Pest Management (IPM) form with the department to document how school officials plan to implement IPM. The state’s Structural Pest Control Act (Act), [225 ILCS 235] requires public schools and licensed day care centers to, when economically feasible, develop and implement an IPM program and resubmit their plans every 5 years. Additionally, all […]

(Beyond Pesticides, November 7, 2013) A study released this week established a strong connection between endometriosis and exposure to two dangerous pesticides: lindane and mirex. While the results are not surprising given past connections between these pesticides and their endocrine-disrupting effects, this new study, Organochlorine Pesticides and Risk of Endometriosis: Findings from a Population-Based Case-Control Study, is one of the first to examine the association between organochlorine pesticides (OCPs) and endometriosis, one of the most common gynecological diseases, in women in the general population. The study’s authors, Kristen Upson, Ph.D. et al,  explained to Environmental Health Perspectives, “Our study suggests that exposure from extensive past use of environmentally persistent OCPs in the United States, or present use in other countries may impact the health of the current generation of reproductive-age women with regard to a hormonally-mediated disease.” In conducting the study, researchers selected a group of women with surgically-confirmed cases of endometriosis from the greater Pacific Northwest area. This group of women was then divided into four groups, based on the level of pesticide in each woman’s blood. Women in the second-highest exposure group for beta-hexacyclochlorohexane (beta-HCH), a byproduct of lindane, had a 70 percent greater risk of endometriosis than […]

(Beyond Pesticides, November 1, 2013) Insecticides commonly used in homes and schools are associated with behavioral problems in children, according to a recent study by Canadian researchers. The study investigates exposure to pyrethroid pesticides, used in more than 3,500 products, including flea and tick controls, cockroach sprays, and head lice controls. The study, Urinary metabolites of organophosphates and pyrethroid pesticides and behavioral problems in Canadian children, published in the journal Environmental Health Perspectives, raises serious concerns about the impact of pyrethroids, which are increasingly used as a replacement for organophosphates. This study uses data from the Canadian Health Measures Survey (2007-2009), a nationally representative survey, so researchers are able to apply these findings to the entire population of Canadian children. In a previous study among U.S. children, researchers at the National Health and Nutrition Examination Survey (NHANES) examined the metabolites of pyrethroids in children below the age of six. Similarly, they found pyrethroid insecticides in more than 70 percent of the samples, concluding that children had significantly higher metabolite concentrations than those of adolescents. Together these studies demonstrate that exposure is widespread, with real impacts to human health. In the recent study, researchers analyzed organophosphate and pyrethroid metabolites in the […]

(Beyond Pesticides, October 29, 2013) Early-life exposure to the herbicide atrazine makes frogs more susceptible to death from chytrid (Batrachochytrium dendrobatidis), a fungal disease implicated in amphibian declines across the globe. The research, Early-life exposure to a herbicide has enduring effects on pathogen-induced mortality, published in the Proceedings of the Royal Society B and led by University of South Florida (USF) biologist Jason Rohr, Ph.D, provides critical information for scientists hoping to stem the global demise of amphibian populations. “Understanding how stressors cause enduring health effects is important because these stressors might then be avoided or mitigated during formative developmental stages to prevent lasting increases in disease susceptibility,” Dr. Rohr explains. Researchers exposed tadpoles to atrazine at levels found in the environment for a period of  six days during the animal’s development, in combination with exposure to chytrid fungus (linked to worldwide amphibian decline), resulted in increased mortality 46 days later. According to the study, “[E]arly-life exposure to atrazine altered growth and development, which resulted in exposure to chytrid at more susceptible developmental stages and sizes, and reduced tolerance of infection, elevating mortality risk at an equivalent fungal burden to frogs unexposed to atrazine. Moreover, there was no evidence of […]

(Beyond Pesticides, October 28, 2013) Scientists at Washington State University (WSU), in a laboratory study,  determined that exposure to the insecticide DDT ””banned in the U.S. since 1972, but still used today in developing countries for malaria abatement programs””impacts multiple generations, ultimately contributing to obesity three generations down the line. The study, published in the journal BMC Medicine, provides the scientific community with new information on multi-generational impacts of pesticide exposure. Lead researcher Michael Skinner, PhD., professor of biological sciences at WSU, and colleagues exposed pregnant rats to DDT to determine the long-term impacts to health across generations. The study, Ancestral dichlorodiphenyltrichloroethane (DDT) exposure promotes epigenetic transgenerational inheritance of obesity, finds that the first generation of rats’ offspring developed severe health problems, ranging from kidney disease, prostate disease, and ovary disease, to tumor development. Interestingly, by the third generation more than half of the rats have increased levels of weight gain and fat storage. In other words, the great grandchildren of the exposed rats are much more likely to be obese. “Therefore, your ancestors’ environmental exposures may influence your disease development even though you have never had a direct exposure,” the study finds. Previous studies have demonstrated that exposure to […]

(Beyond Pesticides, October 3, 2013) According to new research, residents are more highly exposed to organophosphate and pyrethroid pesticides in New York City (NYC) than in the U.S. overall.  Researchers from the city’s Department of Health and Mental Hygiene reviewed the 2004 NYC Health and Nutrition Examination Survey (NYC HANES) to compare its pesticide exposure patterns in an urban environment with the nation as a whole. The NYC HANES includes a biomonitoring component to evaluate pesticide exposures by measuring concentrations of organophosphate and pyrethroid metabolites in urine. According to the authors, the findings underscore the importance of considering pest and pesticide burdens on cities, where a dense population results in a single exposure source affecting many people at the same time when regulating pesticide use. Organophosphate metabolites were measured in the urine of 882 New Yorkers, while 1,452 residents were tested for pyrethroid metabolites. As the researchers explain, the building density and disrepair in parts of NYC likely increased the chances of a pest infestation, which in turn can lead to the reliance on indoor pesticide use. By the 1980’s, organophosphates were the most common class of insecticides in the U.S., and were used indoors until the early 2000’s when […]

(Beyond Pesticides, September 20, 2013) A study of women in Northern California farm towns finds that those living within three miles of strawberries fields treated with methyl bromide gave birth to smaller, lighter babies. Methyl bromides, a fumigant pesticide injected into soils to eliminate soil-borne pests, can volatize into the air exposing nearby neighborhoods. The U.S. and other developed countries have banned the use of methyl bromide under an international treaty that recognized the role of chemicals like methyl bromide to deplete the ozone layer. However, some farmers continue to use the fumigant on strawberries and other crops due to the “critical use exemption” (CUE) stipulation of the laws, which allows the chemical to continue to be used when there are no feasible alternatives. The study, published in Environmental Health Perspectives, examined the health of babies born to 442 pregnant women living in Salinas Valley, CA in 1999 and 2000, when methyl bromide was widely used.   Utilizing data from California’s Pesticide Use Reporting System, the study was able to identify residences that were within 5 kilometers of methyl bromide application. Researchers find that women exposed to the chemical during their second trimester have babies that are  four ounces lighter […]

(Beyond Pesticides, September 11, 2013) In a report released Monday, the Government Accountability Office (GAO) finds that the U.S. Environmental Protection Agency (EPA)’s use and oversight of conditional registrations is lacking and unreliable. Conditional registration allows pesticides onto the consumer market without all the required data to assess the chemical’s safety. This has created many serious human and environmental health problems, including bee decline, tree death and potential increases in human health risks. GAO recommends that EPA better track conditional registrations, however, Beyond Pesticides and other concerned groups urge the agency to cancel registrations until all relevant data is submitted and reviewed. According to the findings of the GAO’s report, EPA’s system for tracking pesticides with conditional registration is unreliable and thus, the total number of conditional registrations granted is unclear.   This lack of a reliable system for managing conditional registrations constitutes an ”˜internal control weakness’ because the agency lacks an effective mechanism for program oversight and decision making, according to federal internal control standards cited by GAO. The report states, “The extent to which EPA ensures that companies submit additional required data and EPA reviews these data is unknown. Specifically, EPA does not have a reliable system, such […]

(Beyond Pesticides, August 30, 2013) Months after Central American health ministries issued a  joint declaration citing kidney disease as a top public health priority, the World Bank just approved a new loan to expand sugar cane plantations in Nicaragua. The Bank’s loan represents renewed support for an industry whose workers have been devastated by the disease, which has increasingly been linked to pesticide exposure and exacerbated by heat stress. Kidney disease afflicts agricultural workers in sugar cane fields, killing thousands each year in Central America as well as in Sri Lanka and India. Scientists have yet to definitively uncover the cause of chronic kidney disease (CKD), although emerging research points to toxic heavy metals contained in pesticides as one of the primary culprits. CKD is a condition characterized by a gradual loss of kidney function and is often lethal for poor agricultural workers. As the kidneys begin to fail, wastes can build in the blood causing complications such as high blood pressure, anemia, weak bones, poor nutritional health and nerve damage. Several published studies demonstrate that exposure to certain  organochlorine pesticide products and their heavy metal contaminants used on sugar cane plantations are causally linked to CKD. The recent joint […]

(Beyond Pesticides, August, 2, 2013) A new study published in the American Journal of Epidemiology concludes that farmers using herbicides are nearly two and a half times as likely to be treated for depression as those who did not use herbicides. Furthermore, farmers who are exposed for greater periods of time are also afflicted with greater risk of developing depression, raising concerns of the harm chemicals can cause to mental health. Building on substantial research supporting the link between pesticide exposure and neurological damage, this study examines the role that pesticides play in the overall health of farmers, and gives further weight to the importance of choosing organic food. Researchers surveyed 567 farmers from France, questioning them on the frequency of their use of fungicides, insecticides, and herbicides, to determine how pesticide exposures were linked to the risk of developing clinical depression. Lead researchers and associate professor at the Harvard School of Public Health, Marc Weisskopf, PhD, said while the results are unclear, they “suggest we should not be ignoring herbicides just because they’re targeting plants.” Previous research has already suggested that pesticides, particularly organophosphates, cause a variety of serious neurological health problems, including Parkinson’s disease. This is not surprising, […]

(Beyond Pesticides, July 12, 2013) New research concludes that exposure to a combination of both arsenic and estrogen, at levels U.S. Environmental Protection Agency (EPA) considers “safe” for humans, can cause cancer at elevated levels in prostate cells. Texas Tech University researchers revealed that humans exposed to a combination of both toxicants were almost twice as likely to develop cancerous cells in their prostate. The study is published in the peer-reviewed journal The Prostate. While it is established that both arsenic and estrogen can cause cancer, the research raises concerns about the dangers of chemicals in combination, and the efficacy of regulations that are established by testing one chemical at a time. Kamaleshwar Singh, PhD., is an assistant professor at the Institute of Environmental and Human Health at Texas Tech. “The majority of cancers are caused by environmental influences,” Dr. Singh remarked to Texas Tech Today, “Only about 5 to 10 percent of cancers are due to genetic predisposition. Science has looked at these chemicals, such as arsenic, and tested them in a lab to find the amounts that may cause cancer. But that’s just a single chemical in a single test. In the real world, we are getting exposed […]

(Beyond Pesticides, June 28, 2013) The U.S. Environmental Protection Agency (EPA) released a draft “State of the Science” report last week acknowledging that low dose responses “do occur in biological systems” while defending its current risk assessment procedures as adequate for evaluating low dose effects. This report comes after EPA’s long running failure to fully implement a 1996 Congressionally mandated program to evaluate endocrine disruptors, and heavy criticism last year from prominent scientists who said EPA’s testing procedures are outdated. In 1999 the Natural Resources Defense Council (NRDC) filed a lawsuit against the EPA for failing to meet a statutory deadline for implementation of the Endocrine Disruptor Screening Program (EDSP) required under the 1996 Food Quality Protection Act, forcing the EPA to make a settlement agreement. As a result of  NRDC et al. v. EPA (No. C-99-03701 CAL) filed in the Northern District of California, EPA agreed to start requiring screening and testing of certain chemicals varying by date, using a tiered system. EPA’s two-tiered screening and testing system, requires that EPA will identify which chemicals are able to interact with the endocrine system in Tier 1. Tier 2 screening process was designed to go one step further, requiring EPA […]