(Beyond Pesticides, October 3, 2024) The American Academy of Pediatrics published a technical report in September on antimicrobial resistance, which it calls a global public health threat, identifying the health implications of antibiotic use in animal agriculture. The lead authors, both medical doctors from the Department of Pediatrics at Vanderbilt University Medical Center, note the rise in antimicrobial-resistant infections that result in increased morbidity, mortality, and health care costs for not only adults, but infants and children as well. “[A]ll use of antimicrobial agents exerts selective pressure that increases the risk of development of resistance,” the authors state, highlighting the importance of limiting antimicrobial uses. “Antimicrobial resistance is an organism’s ability to survive exposure to an antimicrobial agent that was previously an effective treatment. Resistance traits can be acquired either through new mutations or through transfer of genetic material between organisms,” the authors report. Antimicrobial-resistant pathogens, such as bacteria and viruses, can be transmitted “through the food supply, direct contact with animals, environmental pathways, and contact with infected or colonized humans,” they continue. Use of antimicrobial agents, especially over extended periods of time or with repeated exposure, can cause resistance to not only that agent, but to multiple agents. As […]

(Beyond Pesticides, August 30, 2024) There is no more compelling reason to embrace a precautionary pesticide poisoning standard this Labor Day than the need to protect workers. In fact, the Occupational Safety and Health Administration (OSHA) says on its website, Transitioning to Safer Chemicals, that the best way to protect workers is to  “eliminate or reduce hazardous chemicals at the source.” While some try to employ product substitution with “safer” chemicals, Beyond Pesticides urges decision makers to embrace alternative systems, such as organic management systems, that embrace management techniques to meet disease and infestation management goals and use only organic compatible substances. According to OSHA: “In chemical management, [the industrial hygiene principle, known as the hierarchy of controls] guides employers and workers to eliminate or reduce hazardous chemicals at the source by substituting them with safer alternatives. Unlike traditional engineering controls, administrative controls, work practice controls, or personal protective equipment, these strategies can completely eliminate exposure to hazardous chemicals, reduce the potential for chemical accidents, reduce disposal costs, and remove concerns regarding worker compliance and equipment maintenance.” A look through the state and federal databases that track occupational pesticide poisoning for both acute (immediate short-term) and chronic (long-term) pesticide effects […]

(Beyond Pesticides, August 13, 2024) With novel methods to provide a big-picture view of the overlap between high pesticide use and cancer incidence across the U.S, a new study has again linked pesticide exposure to a range of cancers. The study by Jacob Gerkin, D.O. and colleagues, “Comprehensive assessment of pesticide use patterns and increased cancer risk,” published in Frontiers in Cancer Control and Society, examines the association between high-pesticide use and cancer diagnoses along with smoking incidence data and the Social Vulnerability Index, a measure used by the Centers for Disease Control and Prevention (CDC) that includes variables such as poverty, poor housing, and exposures to natural disasters and chemical spills. The researchers consider 69 pesticides used in agriculture that are monitored by the U.S. Department of Agriculture. They use U.S. Geological Survey data to map areas of similar crops and pesticide use patterns and incorporate public health data from the CDC to develop their final picture. In terms of threats to health, cancer remains top of mind for most people. Globally, about ten million people die of cancer each year. And while treatments for cancer and survival times have burgeoned over the years, many cancers—particularly colorectal and breast […]

(Beyond Pesticides, July 16, 2024) Yet another study in the August 2024 journal Ecotoxicology and Environmental Safety has found that exposure to organophosphorus pesticides (OPPs) is correlated with increased suicidal thoughts in some people. This study is just the latest in a long line of studies from around the world that have linked pesticide exposure to mental health conditions, including sleep disorders, depression, and suicidal ideation (SI). As the rate of suicide increased by 30% between 2000 and 2020, there is an urgent public health need to investigate and address all potential contributing factors. A 2019 study, covered in Daily News, found that teens and adolescents living in agricultural areas and exposed to organophosphate (OP) insecticides are at higher risk of depression, In July and January this year, other studies link farmer psychiatric episodes to pesticide exposure, adding to the body of science. Exposure to household pesticides is also linked to depression in a 2020 study.   Study and Methodology  The study entitled “Association between exposure to organophosphorus pesticide and suicidal ideation among U.S. adults: A population-based study,” analyzes information on the mental and physical health of over 5,000 individuals aged 20 and up in the United States. The study aims […]

(Beyond Pesticides, January 11, 2024) In a move to safeguard public and animal health, the U.S. Food and Drug Administration (FDA) warned nine manufacturers and distributors in December last year to stop selling unapproved and misbranded antimicrobial animal drugs, with the director of FDA’s Center for Veterinary Medicine, Tracey Forfa, explaining to the public that “inappropriate use of medically important antimicrobials contributes to the development of antimicrobial resistance, which affects both human and animal health.”  This action and announcement exhibit a higher degree of concern about antimicrobial resistance—understood as a growing worldwide pandemic—than the history and ongoing inaction by the U.S. Environmental Protection Agency (EPA)—resulting in the allowance of widespread nonmedical uses of antibiotics in agriculture and on synthetic (or artificial) turf. Contrary to broad scientific understanding, EPA told a federal appeals court last year that, “There is no data that antibiotic use in agriculture leads to the presence of antibiotic resistance in bacteria of human health concern,” and that “[a]t the present time, there is little evidence for or against the presence of microbes of human health concern in the plant agricultural environment.” The issue of resistance discussed in the scientific literature concerns reduced susceptibility to clinically important antimicrobials, […]

(Beyond Pesticides, January 20, 2023) In late December 2022, the University of California San Francisco made a public apology for the unethical actions of two School of Medicine faculty members who conducted experiments in the 1960s and 1970s on some 2,600 prisoners held at the California Medical Facility at Vacaville. The connection to the work of Beyond Pesticides? The experiments involved exposing male prisoners, by dermal application and via injection, to insecticides and herbicides; this continued until 1977, when the State of California banned all human subject research at state prisons. The investigation and apology — which arose through the work of the UCSF Program for Historical Reconciliation — surface multiple issues surrounding scientific research on human subjects, including ethics and regulations related to consent and to risk of harm. Beyond Pesticides has assiduously chronicled the huge variety of health harms that pesticide use can cause, has reported on many studies evidencing the presence of pesticide residues in human bodies, and in the mid-2000s weighed in on the then-vociferous ethics and regulations controversies surrounding research practices (see more below). UCSF investigated the case of two dermatology professors who, the university learned, had failed to secure consent from the prisoners — […]

(Beyond Pesticides, September 14, 2022) The U.S. Environmental Protection Agency (EPA) is confirming that PFAS (per and polyfluorinated alykyl substances) forever chemicals leach into pesticides from their storage containers, and is taking steps to remove 12 “inert” PFAS ingredients that are currently allowed to be added to pesticide products. The agency’s move is a step toward some measure of health protections from chemicals that may have been widely sprayed throughout many American communities, and have been linked to cancer, liver damage, birth and developmental problems, reduced fertility, and asthma. However, many advocates indicate EPA’s actions on PFAS inerts do not go far enough, and the agency’s findings regarding leaching storage containers are accompanied by no meaningful restrictions on their use. Following reports and preliminary testing conducted in 2020 showing that PFAS chemicals are present in a widely used mosquito adulticide, EPA began investigating the source of this contamination. Testing on the product Anvil 10+10, produced by the company Clarke, resulted in detection of nine different PFAS chemicals. Early indications indicate that the high-density polyethylene (HDPE) containers used to store pesticides contained PFAS substances on their walls, and that those chemicals are leaching into the liquid pesticides stored in contaminated barrels. These […]

(Beyond Pesticides, August 3, 2022) A systematic review of scientific studies on pesticides and fertility finds exposure associated with lower semen quality, DNA fragmentation, and chromosomal abnormalities. Published in the journal Andrology, the review is yet another warning from a long string of researchers sounding the alarm over the connection between global fertility and toxic chemical exposure. With data from the U.S. Centers for Disease Control and Prevention (CDC)  indicating roughly 1 in 5 couples are unable to conceive after a year of trying, and trends continuing to slope downwards, it is critical that contributing factors be identified so that protective changes can be made.   After screening over 1,300 studies, researchers narrowed their review down to 64 papers assessing semen parameters and DNA integrity after pesticide exposure. Each study is analyzed for its design, the pesticide investigated,  the population studied, controls, and reproductive effects determined. Pesticides are evaluated for their impacts to sperm quality and DNA integrity based on their chemical class. Organochlorine insecticides, which are all banned but still persistent in soil, air, water, and food in the United States, include a range of impacts to sperm quality. Higher levels of DDT or its breakdown metabolite DDE are […]

(Beyond Pesticides, April 6, 2022) Conventional apples sold at market and sprayed with synthetic fungicides may not only contain drug-resistant fungi, but function as a transmission reservoir and route to spread these dangerous pathogens, finds research published in mBio late last month by a team of researchers from India and Canada. As reports of fungal resistance rise, particularly in hospitals and among the immunocompromised, there is an urgent need to understand and address the root causes of these emerging disease threats. “When we look at human pathogens, we tend to look at what’s immediate to us,” said study coauthor Jianping Xu, PhD. “But we have to look at it more broadly. Everything is connected, the whole system. Fruit is just 1 example.”   Researchers set out their research with the suspicion that stored fruits sprayed with synthetic fungicides were acting as a source and route of transmission for the deadly fungi Candida auris. This yeast is considered an “emerging fungal pathogen” by the U.S. Centers for Disease Control and Prevention (CDC), and has increased its rate of infection significantly since its initial identification in the mid 1990s. The fungi has been found in every continent save Antarctica. It has proven to […]

(Beyond Pesticides, May 18, 2021) Organic meat is far less likely to be adulterated with multi-drug resistant bacteria (MDRB) than conventional meat, according a study published earlier this month in Environmental Health Perspectives. The research by experts at John Hopkins Bloomberg School of Public Health is the latest news on the health and safety benefits of choosing organic, which prohibits the regular use of risky antibiotics, for one’s food purchases. Scientists indicate that contaminated foods pose serious dangers for consumers, public health, and the economy at large. “The presence of pathogenic bacteria is worrisome in and of itself, considering the possible increased risk of contracting foodborne illness,” senior author Meghan Davis, PhD, associate professor at the Bloomberg School said. “If infections turn out to be multidrug resistant, they can be more deadly and more costly to treat.” To determine the level of contamination in various packaged meats, scientists turned to the National Antimicrobial Resistance Monitoring System (NARMS), a collaborative program between the U.S. Centers for Disease Control and Prevention, the U.S. Food and Drug Administration (FDA), and the U.S. Department of Agriculture. For a five year period spanning 2012-2017, NARMS collected meat products (chicken breast, ground beef, ground turkey, and […]

(Beyond Pesticides, November 24, 2020) Reinforcing a body of scientific evidence, a new study finds that eating organic food lowers one’s risk of developing type 2 diabetes. With 1 in 10 (34 million) Americans afflicted with type 2 diabetes, and 1 in 3 (88 million) with prediabetes, new strategies focused on prevention are urgently needed. The results of the study, published by a team of French and American researchers in the International Journal of Behavioral Nutrition and Physical Activity, reinforce the triple bottom line (profit, people, and the environment) benefits of organic food for public health, the environment, and the wider economy. Scientists used data from NutriNet-Santé, a massive study including over 170,000 participants (averaging 52 years old) that regularly respond to questions concerning lifestyle, dietary intake, body type, physical activity, and health status. Roughly 33,000 NutriNet-Santé participants completed food frequency questionnaire regarding how often they consumed organic food. After four years, 293 surveyed individuals had been diagnosed with type 2 diabetes. Researchers then looked at how organic food consumption affected the risk of developing the disease, adjusting for body mass index, gender, family history of diabetes, physical activity, education, economic status, occupation, smoking, and alcohol consumption. Higher organic food […]

(Beyond Pesticides, August 28, 2020) The Environmental Protection Agency (EPA) has granted “emergency” permission to the State of Texas to allow the use of SurfaceWise®2, an unregistered pesticide, as an anti-viral surface coating. The manufacturer, Allied Bioscience, says the compound can kill coronaviruses (including SARS-CoV-2) starting at two hours post application and for up to seven days, but it is not included on EPA’s List N, of disinfectants effective against SARS-CoV-2. EPA has permitted this use via the authority of Section 18 of the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), which allows for “emergency” use of non-registered pesticides, typically to deal with extreme threats to agricultural activities. It is rarely used for public health emergencies. Beyond Pesticides recognizes the need for protection from transmission of the novel coronavirus, and maintains that it ought to and can be done without exposing people to toxic synthetic pesticides that have not undergone evaluation for safety. See Beyond Pesticides’ guidance on effective and safe precautions against the novel coronavirus. The Texas Department of Agriculture secured the EPA exemption, making the state the first to do so; Allied BioScience is pursuing this emergency waiver across all 50 states. The exemption grants American Airlines and two health […]

(Beyond Pesticides, April 24, 2020) The Centers for Disease Control and Prevent (CDC) has released a study showing a sharp increase—62% in some cases—in calls to poison hotlines about exposures to toxic household cleaners and disinfectants. This poisoning comes with the advent of the novel Coronavirus pandemic, as public health and government officials, and many media outlets have sensibly recommended that people regularly disinfect “high touch” surfaces and objects in their homes and other surroundings, but have not issued warnings on toxic effects nor the availability of lower toxicity or least-toxic products. Compliance with cleaning (sanitizers) and disinfection recommendations is an important public and personal health undertaking, but in this Covid-19 rigor lies a poison problem: the toxicity, as Beyond Pesticides has explained, of some cleaning and disinfecting products that are permitted by the Environmental Protection Agency (EPA) for sale and use. There are safer ways to disinfect those light switches, TV remotes, doorknobs, faucets, etc. First, a basic distinction between cleaning (also called sanitizing)and disinfecting: EPA offers definitions of the differences. “Cleaning is done with water, a cleaning product, and scrubbing. Cleaning does not kill bacteria, viruses, or fungi, which are generally referred to as ‘germs.’ Cleaning products are used […]

(Beyond Pesticides, March 16, 2020) As the number of people infected with Novel Coronavirus Disease 2019 (COVID-19) increases, many people are looking for sound advice about how to protect themselves and their families. There is much uncertainty. “It’s fair to say that as the trajectory of the outbreak continues, many people in the United States will at some point in time either this year or next be exposed to this virus, and there’s a good chance many will become sick,” said Nancy Messonnier, M.D., director of the Centers for Disease Control and Prevention’s (CDC’s) National Center for Immunization and Respiratory Diseases. “But … based on what we know about this virus, we do not expect most people to develop serious illness.” Tell EPA not to recommend toxic chemicals for disease prevention. While people are seeking answers, EPA’s published list, Registered Antimicrobial Products for Use Against Novel Coronavirus SARS-CoV-2, the Cause of COVID-19, does not offer helpful advice. The list contains products containing toxic chemicals such as chlorine bleach, peroxyacetic acid, alkyl dimethyl benzyl ammonium chlorides, didecyl dimethyl ammonium chloride, and other “quats,” sodium dichloro-s-triazinetrione, and hydrochloric acid. In addition to their outright toxicity, some of these can also trigger asthmatic attacks. On the other hand, CDC’s website makes it […]

(Beyond Pesticides, April 25, 2019) As reported by Mother Jones, the New York Times (NYT) published, on April 6, a distressing report about a deadly fungus that has been advancing steadily across the world during the past five years. Candida auris is an emerging fungal pathogen that threatens those with compromised or immature immune systems, such as infants, the elderly, people taking steroids for autoimmune disorders, diabetics, those undergoing chemotherapy, and even smokers. Nearly half of those who contract a C. auris infection die within 90 days. One of the factors making this fungus so deadly is that it has developed resistance to existing antifungal medicines, with 90% of infections resistant to one drug, and 30% to two or more. As is true for resistant bacteria, culprits in C. auris’s development of resistance may be the overuse of antifungal medications in health care and overreliance on fungicides in agriculture. The Centers for Disease Control and Prevention (CDC) has added C. auris to its list of pathogens considered “urgent threats.” It is an “emerging fungal pathogen,” meaning that the incidence of infection has been increasing across multiple countries since it was first recognized in 2009 in Japan (although a different strain had […]