(Beyond Pesticides, Aug 2, 2010) A new report conducted by an Ann Arbor, Michigan based coalition of health and environmental groups estimates that children’s exposure to toxic chemicals, including pesticides, cost Michigan billions of dollars each year. The study examines the costs associated with four environmentally related childhood diseases: lead poisoning, asthma, pediatric cancer, and neurodevelopmental disorders. Treating these four disorders costs the state of Michigan an average of $5.85 billion annually. The study, “The Price of Pollution: Cost Estimates of Environment-Related Childhood Disease in Michigan” was released in time for the US House Energy and Commerce Committee hearings on the Toxic Chemicals Safety Act of 2010, an overhaul of the 1976 Toxic Substances Control Act (TSCA). Using conservative estimates researchers consider direct costs such as medical treatment, as well as less direct costs such as parent wage losses. The study also notes the substantial emotional costs to families dealing with these potentially life threatening or debilitating conditions which cannot be quantified. Lead poisoning is found to be the most costly of the diseases studied, costing on average $4.85 billion annually, followed by childhood asthma, pediatric cancer, and neurodevelopmental disorders. These four disorders alone cost the state of Michigan 1.5% […]

(Beyond Pesticides, July 23, 2010) A new study published in BioMed’s online journal, Environmental Health, links endocrine disrupting pesticides and other chemicals in household cleaning products to an elevated risk of breast cancer. Researchers at the Silent Spring Institute in Newton, MA and Boston University found that women who use household cleaners more often have double the risk of breast cancer, compared to women who use household cleaners less frequently. The study includes over 1,500 women selected from Cape Cod, MA and found a correlation between cases of breast cancer and the number of women who reported using household cleaners, particularly solid, slow-release air fresheners when used more than seven times a year, and mold removers when used more than once a week. The antimicrobials, phthalates and alkylphenolic surfactants often found in mold and mildew products are associated with various health and environmental issues. The antimicrobial triclosan for example, can cause skin irritation, allergy susceptibility, bacterial and compounded antibiotic resistance, and dioxin that jeopardizes fragile aquatic ecosystems. The study highlights methylene chloride (in some fabric cleaners), nitrobenzene (soaps, polishes), perfluorinated compounds (stainresistant, waterproof coatings), phthalates (surfactants), alkylphenols (solvents), parabens (preservatives), triclosan, and polycyclic musks (fragrance) as ingredients of concern. Past […]

(Beyond Pesticides, July 6, 2010) A review report published last Friday highlights that some research studies indicate that pesticide exposure either prior to conception, during pregnancy or during childhood appears to increase the risk of childhood cancer, with maternal pesticide exposure during pregnancy being most consistently associated with childhood cancer. Furthermore, the report notes that several studies indicate that farmers are at greater risk of developing certain cancers than the general population. In particular, several studies strongly suggest that pesticide exposures are associated with some cases of non-Hodgkin’s lymphoma (NHL), leukemia, prostate cancer and other hormone related cancers. The report, A Review of the Role Pesticides Play in Some Cancers: Children, farmers and pesticide users at risk?, is published by the United Kingdom organization CHEM (Chemicals, Health and Environment Monitoring) Trust. “Pesticide exposures may interact with other chemical exposures and genetic factors, to cause cancer. Research suggests that pregnant women, in particular, should avoid direct exposure to pesticides, if possible,” said Gwynne Lyons, Director of CHEM Trust and report co-author. “It is high time that the UK was more supportive of EU proposals to take a tougher approach to reducing exposure to potentially harmful chemicals. If the UK is to […]

(Beyond Pesticides, May 11, 2010) Even with the growing body of evidence linking environmental exposures to cancer in recent years, a report released May 6, 2010 by the President’s Cancer Panel finds that the true burden of environmentally-induced cancer is greatly underestimated. The Panel’s report, Reducing Environmental Cancer Risk: What We Can Do Now, concludes that while environmental exposure is not a new front on the war on cancer, the grievous harm from this group of carcinogens has not been addressed adequately by the nation’s cancer program. “There remains a great deal to be done to identify the many existing but unrecognized environmental carcinogens and eliminate those that are known from our daily lives — our workplaces, schools and homes,” said LaSalle D. Leffall, Jr., M.D., chair of the Panel. “The increasing number of known or suspected environmental carcinogens compels us to action, even though we may currently lack irrefutable proof of harm,” he added. Beyond Pesticides applauds the chairman’s precautionary approach and encourages President Obama to heed the panel’s call to “use the power of your office to remove the carcinogens and other toxins from our food, water, and air that needlessly increase health care costs, cripple our Nation’s […]

(Beyond Pesticides, April 12, 2010) Environmental, public health, labor and farmworker advocacy organizations from across the country have filed a petition asking the U.S. Environmental Protection Agency (EPA) to rescind the Bush administration era approval of the highly toxic fumigant pesticide methyl iodide in light of troubling new findings uncovered in California studies. The petition was submitted on the birthday of famed farmworker rights advocate Cesar Chavez, who drew national attention to pesticide misuse on grapes in the 1980s. “In 1988, Cesar Chavez again put his life on the line to draw attention to farmworker rights when he protested the use of pesticides with a 36-day, water-only fast,” said Jeannie Economos, Pesticide Safety and Environmental Health Project Coordinator at Farmworker Association of Florida. “Over 20 years later, we should not have to be fighting the same battles. Methyl iodide use takes us in the dead wrong direction for workers, public health and the future of agriculture.” The movement to ban methyl iodide follows the legacy of Cesar Chavez: the pesticide poses significant, direct risks to farmworkers, their families and neighboring communities. Methyl iodide is a water contaminant, nervous system poison, thyroid toxicant and is listed on California’s Proposition 65 list […]

(Beyond Pesticides, April 1, 2010) While most previous literature on melanoma has focused on host factors and sun exposure, new research shows a link between several pesticides and this deadly form of skin cancer. Epidemiologists from University of Iowa, the National Institute of Environmental Health Sciences and National Cancer Institute found that agricultural workers who apply certain pesticides to farm fields are twice as likely to contract melanoma, providing support for the hypotheses that agricultural chemicals may be another important source of skin cancer risk. The study, “Pesticide use and cutaneous melanoma in pesticide applicators in the Agricultural Heath Study” was published last month in the journal Environmental Health Perspectives. It examines cancer rates in 56,285 pesticide applicators in Iowa and North Carolina as part of the federal government’s Agricultural Health Study, a large, long-term study of pesticide applicators and their spouses. Researchers asked the pesticide applicators how often they were exposed to 50 pesticides and compared their cancer rates. Each person’s exposure was then approximated by adding up the total days that the workers had been exposed and using information from survey results on how the chemicals were applied and what protective equipment was being used. The pesticides that […]

(Beyond Pesticides, July 29, 2009) A new study by researchers at the Lombardi Comprehensive Cancer Center at Georgetown University finds a higher level of common household pesticides in the urine of children with acute lymphoblastic leukemia (ALL), a cancer that develops most commonly between three and seven years of age. The findings are published in the August issue of the journal Therapeutic Drug Monitoring. Researchers, in the study entitled, “Pediatric Acute Lymphoblastic Leukemia and Exposure to Pesticides,” caution that these findings, which do not establish a cause-and-effect relationship, suggest an association between pesticide exposure and development of childhood ALL. “In our study, we compared urine samples from children with ALL and their mothers with healthy children and their moms. We found elevated levels of common household pesticides more often in the mother-child pairs affected by cancer,” says the study’s lead investigator, Offie Soldin, Ph.D., an epidemiologist at Lombardi. Dr. Soldin cautions, “We shouldn’t assume that pesticides caused these cancers, but our findings certainly support the need for more robust research in this area.” Previous studies have found that exposures to certain pesticides increases the risk of developing certain cancers and degenerative diseases. The study was conducted between January 2005 and […]

(Beyond Pesticides, June 16, 2009) A study involving 678 individuals who apply pesticides, culled from a U.S. Agricultural Health Study of over 50,000 farmers, recently found that exposure to certain pesticides doubles one’s risk of developing an abnormal blood condition called MGUS (monoclonal gammopathy of undetermined significance) compared with individuals in the general population. The disorder, characterized by an abnormal level of a plasma protein, requires lifelong monitoring as it is a pre-cancerous condition that can lead to multiple myeloma, a painful cancer of the plasma cells in the bone marrow. The study will appear in the June 18 issue of Blood, the official journal of the American Society of Hematology. “Our study is the first to show an association between pesticide exposure and an excess prevalence of MGUS,” said lead author Ola Landgren, M.D., Ph.D., of the National Cancer Institute (NCI), which is part of the National Institutes of Health, U.S. Department of Health and Human Services. “This finding is particularly important given that we recently found in a large prospective cancer screening study that virtually all multiple myeloma patients experienced a MGUS state prior to developing myeloma.” “As several million Americans use pesticides, it’s important that the risks […]

(Beyond Pesticides, May 28, 2009) Two commonly used herbicides, pendimethalin and EPTC, show a statistically significant exposure-response association with pancreatic cancer. The new study, “Agricultural Pesticide Use And Pancreatic Cancer Risk In The Agricultural Health Study Cohort,” published earlier this month in the International Journal of Cancer, is a case-control study of pesticide applicators and their spouses in Iowa and North Carolina. After controlling for age, smoking and diabetes, the study finds a three-fold increased risk with lifetime pendimethalin use and a two-and-a-half-fold increased risk with lifetime use of EPTC when compared to those that never used the chemicals. Among the 24 pesticides examined, having ever used one of five pesticides (trifluralin, chlorimuron-ethyl, pendimethalin, EPTC or heptachlor) shows at least a 40 percent excess risk of pancreatic cancer. According to the U.S. EPA’s pesticide sales and usage statistics, pendimethalin is the third most commonly used home and garden (and other non-agricultural use) herbicide and the 7th most commonly used herbicide in agriculture, totaling 21-30 million pounds applied annually in the U.S. Pendimethalin is listed by the U.S. EPA as a Group C – Possible Human Carcinogen and is a suspected endocrine disruptor. Pendimethalin has been found to cause central nervous […]

(Beyond Pesticides, January 5, 2009) According to a new study published December 2008 in the online edition of Environmental Health Perspectives, hexavalent chromium (or chromium VI) found in the wood preservatives chromated copper arsenate (CCA) and acid copper chromate (ACC), is a human carcinogen following chronic oral exposure. Previous studies have shown that hexavalent chromium compounds can increase the risk of lung cancer via inhalation exposure. Chromium VI is the notorious chemical that caused cancer in the residents of Hinkley, CA and brought to light by the work of Erin Brockovich. The National Toxicology Program (NTP) conducted 2-year drinking water studies of chromium VI (as sodium dichromate dihydrate) in male and female F344/N rats and B6C3F1 mice. Exposure resulted in increased incidences of rare neoplasms of the squamous epithelium that lines the oral cavity (oral mucosa and tongue) in male and female rats, and of the epithelium lining the small intestine in male and female mice. The authors determined that chromium Vi is carcinogenic following administration in drinking water to male and female rats and mice. The International Agency for Research on Cancer (IARC), the U.S. Department of Health and Human Services, and the Environmental Protection Agency (EPA) each have […]

(Beyond Pesticides, November 13, 2008) The Canadian Cancer Society is holding a conference to look at the possibility of advocating for stricter farm pesticide laws. The Cancer Society has been a vocal advocate for the cosmetic pesticide restrictions that have passed in the provinces of Ontario and Quebec as well as many municipalities, but it has not yet taken a stance on the much larger use of agricultural pesticides. Health Canada, the Canadian entity responsible for pesticide regulation insists, as the U.S. Environmental Protection Agency does in the U.S., that registered pesticides do not pose a substantive health risk when used as directed, but mounting scientific evidence shows otherwise. Many of the same chemicals that Canadian provinces have banned for cosmetic use, such as the herbicide 2,4-D, are used in much higher volumes in agriculture than on lawns. Since the Cancer Society is a strong voice in favor of the cosmetic pesticide bans because of the dangers of pesticides, it is logical that they would also be concerned about agricultural pesticide use. In other words, “It’s very hard to argue that the cosmetic use of pesticides poses a public-health risk, including cancer risk, and not examine what is going on […]

(Beyond Pesticides, October 14, 2008) Exposure to glyphosate or MCPA can more than double one’s risk of developing non-Hodgkin lymphoma (NHL), according to a new epidemiological study published in the October issue of the International Journal of Cancer. The case-control study finds a 2.02 odds ratio (OR) for exposure (two times the chance of contracting the illness) to glyphosate, a 2.81 OR for exposure to MCPA, and a 1.72 OR for exposure to herbicides. According to EPA, glyphosate is the most commonly used pesticide in the U.S. with 103 to 113 million pounds used annually. MCPA is a phenoxyacetic acid pesticide, a family of pesticides that has previously been linked to cancer and includes 2,4-D and mecoprop (MCPP). NHL is a cancer of the immune system. There are several different types of NHL, which are differentiated by the type of immune cell that is cancerous, the characteristics of the cancerous cell, and different genetic mutations of the cancerous cells. Treatment for NHL varies depending on NHL type, patient age, and other existing medical conditions. The incidence of NHL has been increasing over the past several decades. The link between pesticides and cancer has long been a concern. While agriculture has […]

(Beyond Pesticides, October 10, 2008) A study published in the American Journal of Epidemiology [Vol. 167, No. 8] finds women who have used herbicides are twice as likely to have meningioma, a specific kind of brain tumor. The study, “Occupational exposure to pesticides and risk of adult brain tumors,” was conducted by the National Cancer Institute. The authors examined the risk of two types of brain cancer, glioma and meningioma, associated with occupational exposure to insecticides and herbicides in a hospital-based, case-control study of brain cancer. Cases were 462 glioma and 195 meningioma patients diagnosed between 1994 and 1998 in three U.S. hospitals. Controls were 765 patients admitted to the same hospitals for nonmalignant conditions. Occupational histories were collected during personal interviews. Exposure to pesticides was estimated by use of a questionnaire, combined with pesticide measurement data abstracted from published sources. The researchers found no overall link between brain cancer and on-the-job exposure to pesticides or herbicides. However, looking closer at the data, the researchers noticed that women who reported using herbicides had a more than doubled risk for meningioma compared with women who never used herbicides, and there were significant trends of increasing risk with increasing years of herbicide […]

(Beyond Pesticides, August 8, 2008) University of California Davis Cancer Center physicians recently released results of research showing that Vietnam War veterans exposed to Agent Orange have greatly increased risks of prostate cancer and even greater risks of getting the most aggressive form of the disease as compared to those who were not exposed. The findings, which appear online now and will be published in the September 15 issue of the journal Cancer, are the first to reliably link the herbicide with this form of cancer by studying a large population of men in their 60s and the prostate-specific antigen (PSA) test to screen for the disease. “While others have linked Agent Orange to cancers such as soft-tissue sarcomas, Hodgkin’s disease and non-Hodgkin’s lymphoma, there is limited evidence so far associating it with prostate cancer,” said Karim Chamie, lead author of the study and resident physician with the UC Davis Department of Urology and the VA Northern California Health Care System. “Here we report on the largest study to date of Vietnam War veterans exposed to Agent Orange and the incidence of prostate cancer.” Chamie also said that, unlike previous studies that were either too small or conducted on men […]

(Beyond Pesticides, February 13, 2008) The publication of a federal study undertaken by the Centers for Disease and Control (CDC) has been blocked for more than seven months because it contains “alarming information” of evidence of elevated infant mortality and cancer rates in the region surrounding the Great Lakes.The report entitled, Public Health Implications of Hazardous Substances in the Twenty-Six U.S. Great Lakes Areas of Concern, was commissioned by the International Joint Commission (IJC), an independent organization that advises the U.S. and Canadian governments on the use and quality of boundary waters between the two countries, and compiled by the CDC’s Agency for Toxic Substances and Disease Registry (ATSDR). The report outlines the “areas of concern” in which more than nine million people in major metropolitan areas as Chicago, Cleveland, Detroit, and Milwaukee, face higher health risks from exposure to dioxin, PCBs, pesticides, lead, mercury, or six other hazardous pollutants.Contributors to the report include senior experts from the Environmental Protection Agency, CDC, universities, as well as federal and state researchers. These experts have been reviewing data since 2004 and have found low birth weights, elevated rates of infant mortality and premature births, and elevated death rates from breast cancer, colon […]

(Beyond Pesticides, February 7, 2008) The U.S. Environmental Protection Agency (EPA) has awarded more than $500,000 in federal grant funds to several states and non-profit organizations to be used for programs to educate health care providers and women of childbearing age on environmental health risks.The grants were provided to five states and non-profit organizations in Ohio, Michigan, Oregon, Florida, and Texas, and are to focus on educating women, especially pregnant women, on the hazards of environmental contaminants and hazards to children. Health issues such as exposure to mercury, lead, environmental tobacco smoke, chemicals, pesticides, drinking water contaminants, and indoor and outdoor air contaminants have been especially targeted. These grants are estimated to benefit 3,000 health care providers and 10,000 women of childbearing age.“We’re giving pregnant women information on how to avoid exposure to certain environmental hazards to give children a healthy start to life,” said Dona Deleon, acting director, Office of Children’s Health Protection and Environmental Education. “These grants help the public health community reach women during this important time in their lives.”According to the EPA, pregnancy is a time for joy and celebration, but it is also a time to be especially careful about the environment in which one […]

(Beyond Pesticides, August 7, 2007) In a study that examines the influence of age of exposure on the magnitude of the association between DDT and breast cancer risk finds that women who were exposed to DDT before the age of 14 are five times more likely to develop breast cancer later in life. In contrast, the study finds exposure after adolescence does not increase risk. The data used in the study targets the age of a woman in 1945 as an indicator for the youngest possible age for a woman to be exposed to DDT, since DDT was first introduced to the U.S. for mosquito control in 1945. The researchers, from the Center for Research on Women’s and Children’s Health, Public Health Institute at Berkeley, California and the Mount Sinai School of Medicine, analyzed blood that had been collected from women between 1959 and 1967 – years during which the use of DDT was at its highest. “DDT and breast cancer in young women: New data on the significance of age at exposure,” published last week in the online edition of the journal Environmental Health Perspectives, is “the first study specifically designed, a priori, to consider whether age at exposure […]

(Beyond Pesticides, May 15, 2007) According to a study commissioned by Susan G. Komen for the Cure and the Silent Spring Institute, 216 chemicals, many found in urban air and everyday consumer products, cause breast cancer in animal tests. The study, “Environmental Factors in Breast Cancer,” the most comprehensive review to date of scientific research on environmental factors that may increase breast cancer risk, was published in the online version of the American Cancer Society’s journal Cancer on May 14, 2007. The state-of-the-science review collected and assessed existing scientific reports on potential links between specific environmental factors and breast cancer. The researchers synthesized national and international data sources and identified 216 chemicals that cause breast tumors in animals, including ten pesticides. They used the information to create a searchable online database featuring detailed information on the carcinogens. The database, accessible at www.komen.org/environment, is available free of charge. The database includes references to 900 studies, 460 of which are human breast cancer studies that were critically evaluated by the research team. The studies measure breast cancer risk related to body size, physical activity, environmental pollutants, and prospective studies of diet. For each study, bibliographic information, key methods and findings, and a […]

(Beyond Pesticides, January 30, 2007) Breast cancer groups across the country have a new issue to add to the repertoire of risk factors: Pesticide use. A study published online in the American Journal of Epidemiology has found a strong link between residential pesticide use and breast cancer risk in women. Responding to the study, Susan Teitelbaum, Ph.D., assistant professor in the department of community medicine at the Mount Sinai School of Medicine in New York, says the options are simple”” “Stop using pesticides.” The study, published December 13, is the first to examine the relation between breast cancer and pesticides through self-reported residential pesticide use. Using women from New York, the study looks not at one or two incidents of pesticide contact, but at the impact of lifelong pesticide use in the home, lawn and garden. Using a sample of 1,508 women who were diagnosed with breast cancer between 1996 and 1997, the study compares these women to 1,556 control subjects who were randomly selected. The results show that those women whose blood samples had higher levels of organochlorines are at an increased risk of breast cancer. Organochlorines are a broad class of chemicals, including DDT, dieldrin, and chlordane, and […]