(Beyond Pesticides, September 21, 2012) A new French study reports that rats fed a diet of Roundup-tolerant genetically modified (GM) corn had an increased risk of developing tumors, suffering organ damage and dying prematurely. The study is the first animal feeding trial studying the lifetime effects of exposure to Roundup tolerant GM corn and has prompted the European Food Safety Authority to look into the study’s results. However, it is also being criticized by some other scientists who said the methodology was flawed and that other research had not found similar problems. The study, “Long term toxicity of a Roundup herbicide and a Roundup-tolerant genetically modified maize,” which is being published in the peer-reviewed journal Food and Chemical Toxicology, was led by Gilles-Eric Séralini, PhD, at the University of Caen in France. The study followed 200 rats for two years, the life-span of the rat, but far longer than the typical 90-day feeding studies used in regulatory assessments and subsequent approval of GM crops. The rats were fed different amounts of NK603 corn developed by Monsanto to be resistant to the herbicide Roundup. In some cases, the corn had been sprayed in the field with Roundup. Other rats were given […]

(Beyond Pesticides, September 20, 2012) Raising questions about the adequacy of pesticide regulation, historically and ongoing, Consumer Reports published a new study yesterday that finds “worrisome” levels of inorganic arsenic in rice products. Arsenic is a known human carcinogen. This new report follows its earlier one that finds high levels of arsenic in apple and grape juice. The report finds elevated arsenic levels across organic and conventional products, raising serious questions about widespread environmental and soil contamination from past and continuing arsenical pesticide use. Although organic arsenic occurs naturally in the environment, it is synthetic inorganic arsenic that poses the biggest health hazards to humans and animals. So, humans are exposed to two kinds of the carcinogen in air, water, soil, and food sources. But unlike organic arsenic, which is found naturally in the environment, inorganic arsenic is present in our food as a result of pesticide application and animal feed. Arsenic is added to chicken feed as a supplement to control intestinal parasites and promote growth. It is consequently transferred into the meat of the animals and turns up in chicken manure. Arsenic is also widely used in the treatment of utility poles and in the arsenical herbicide MSMA […]

(Beyond Pesticides, November 15, 2011) Research published in the online edition of Environmental Health Perspectives finds that exposure to certain pesticides elevates the risk of non-Hodgkin’s Lymphoma (NHL). The study, “A Prospective Study of Organochlorines in Adipose Tissue and Risk of non-Hodgkin’s Lymphoma,” finds a positive correlation between levels of the organochlorine pesticides DDT, cis-nonachlor, chlordane, and their breakdown products in human fat tissue and the often deadly form of cancer. The researchers from the Danish Cancer Society’s Institute of Cancer Epidemiology conducted a case-cohort study using a prospective Danish cohort of 57,053 persons enrolled between 1993 and 1997. Within the cohort they identified 256 persons diagnosed with NHL in the population-based nationwide Danish Cancer Registry and randomly selected 256 sub-cohort persons. The research team measured concentrations of eight pesticides and ten polychlorinated biphenyl congeners (PCBs) in fat tissue collected upon enrollment. The results indicate a higher risk of NHL in association with higher fat tissue levels of DDT, cis-nonachlor and oxychlordane, but shows no association with PCBs. Because the tissue samples were taken up to 15 years prior to the cancer diagnosis, the research suggests that exposure to these organochlorines increases the risk of NHL later in life and […]

(Beyond Pesticides, August 30, 2011) A new study finds that older men living in California’s Central Valley are more likely to develop prostate cancer if they were exposed to certain agricultural pesticides than those who were not exposed. The study examines exposure via drift rather than occupational exposure, although similar results have been noted in farmworker populations. Exposure to methyl bromide or various organochlorine pesticides increased the risk of cancer by about one and a half times. The study, “Prostate cancer and ambient pesticide exposure in agriculturally intensive areas in California,” was published in the June 2011 issue of the American Journal of Epidemiology. The researchers from the University of Southern California’s Keck School of Medicine recruited 173 men between the ages of 60 to 74 from 670 identified by the California Cancer Registry as being diagnosed with prostate cancer between August 2005 and July 2006 in California’s Central Valley. The authors used calendars and questionnaires to determine where they lived and worked between 1974 and 1999, and compared this to historical data of the corresponding area’s agricultural pesticide use from state pesticide use reports and land use records. In comparison with unexposed persons, increased risks of prostate cancer were […]

(Beyond Pesticides, May 10, 2011) In three new studies published in the May issue of the journal Health Affairs (Vol. 30, No. 5), Mount Sinai School of Medicine researchers reveal the staggering economic impact of toxic chemicals and air pollutants in the environment, and propose new legislation to mandate testing of new chemicals and also those already on the market. The studies, “Environmental Disease in Kids Cost $76.6 Billion in 2008,” “Children’s Vulnerability to Toxic Chemicals,” and “Pollutants and Respiratory Illness in Infants,” are available on the Health Affairs website. Leonardo Trasande, MD, Associate Professor of Preventive Medicine and Pediatrics at Mount Sinai School of Medicine, analyzed the costs of conditions — including lead poisoning, childhood cancer, asthma, autism, and attention deficit hyperactivity disorder (ADHD) — associated with exposure to toxic chemicals. Dr. Trasande and his team calculated the annual cost for direct medical care and the indirect costs, such as parents’ lost work days, and lost economic productivity caring for their children, of these diseases in children. The researchers found the annual cost in the United States to be an estimated $76.6 billion, representing 3.5 percent of all U.S. health care costs in 2008. The breakdown includes: lead poisoning […]

(Beyond Pesticides, January 4, 2011) A report released by the Environmental Working Group (EWG) finds that drinking water in 31 cities across the country is contaminated with hexavalent chromium, or chromium-6, a carcinogenic chemical contaminant with numerous sources including treated wood utility poles that line streets and backyards across the the United States. Wood treated with chromated copper arsenate (CCA), such as playgrounds, decks, and railroad ties, in addition to utility poles, can leach the chemicals into soils and groundwater, creating serious risks to public health. Other common sources of chromium-6 pollution include discharge from steel and pulp mills as well as metal-plating and leather-tanning facilities. It can also pollute water through erosion of natural deposits. The use of CCA in the treatment of utility poles is notable not only because of the presence of poles in numerous communities throughout the country, but also because utility companies often donate or sell decommissioned poles, which are then used by homeowners to line walkways and gardens or create structures around the yard, unknowingly contributing to the proliferation of these toxic substances. Beyond Pesticides has worked on the issue of wood treatments, including CCA, since the mid-1980s and has advocated for the adoption […]

(Beyond Pesticides, October 5, 2010) A new report by the Breast Cancer Fund, a national organization working to eliminate the environmental causes of breast cancer, presents a summary of the scientific data on the environmental causes of the disease. The report catalogs the growing evidence linking breast cancer to, among other factors: synthetic hormones in pharmaceuticals, cosmetics and meat; pesticides in food; solvents in household cleaning products; BPA in food containers; flame retardants in furniture; and radiation from medical treatments. The report also highlights impacts on the most vulnerable populations (including infants, pregnant women, African-American women and workers), and outlines the policy initiatives required to develop a national breast cancer prevention plan. The report, State of the Evidence: The Connection Between Breast Cancer and the Environment, is the sixth edition published by the Breast Cancer Fund. “With each new edition of the report, the growing scientific evidence compels us to act to prevent breast cancer,” said Jeanne Rizzo, RN, president of the Breast Cancer Fund. “This Breast Cancer Awareness Month, our message is clear: we must move beyond awareness to prevention.” The report states that a woman’s lifetime risk of breast cancer is 1 in 8””representing a dramatic increase since […]

(Beyond Pesticides, Aug 2, 2010) A new report conducted by an Ann Arbor, Michigan based coalition of health and environmental groups estimates that children’s exposure to toxic chemicals, including pesticides, cost Michigan billions of dollars each year. The study examines the costs associated with four environmentally related childhood diseases: lead poisoning, asthma, pediatric cancer, and neurodevelopmental disorders. Treating these four disorders costs the state of Michigan an average of $5.85 billion annually. The study, “The Price of Pollution: Cost Estimates of Environment-Related Childhood Disease in Michigan” was released in time for the US House Energy and Commerce Committee hearings on the Toxic Chemicals Safety Act of 2010, an overhaul of the 1976 Toxic Substances Control Act (TSCA). Using conservative estimates researchers consider direct costs such as medical treatment, as well as less direct costs such as parent wage losses. The study also notes the substantial emotional costs to families dealing with these potentially life threatening or debilitating conditions which cannot be quantified. Lead poisoning is found to be the most costly of the diseases studied, costing on average $4.85 billion annually, followed by childhood asthma, pediatric cancer, and neurodevelopmental disorders. These four disorders alone cost the state of Michigan 1.5% […]

(Beyond Pesticides, July 23, 2010) A new study published in BioMed’s online journal, Environmental Health, links endocrine disrupting pesticides and other chemicals in household cleaning products to an elevated risk of breast cancer. Researchers at the Silent Spring Institute in Newton, MA and Boston University found that women who use household cleaners more often have double the risk of breast cancer, compared to women who use household cleaners less frequently. The study includes over 1,500 women selected from Cape Cod, MA and found a correlation between cases of breast cancer and the number of women who reported using household cleaners, particularly solid, slow-release air fresheners when used more than seven times a year, and mold removers when used more than once a week. The antimicrobials, phthalates and alkylphenolic surfactants often found in mold and mildew products are associated with various health and environmental issues. The antimicrobial triclosan for example, can cause skin irritation, allergy susceptibility, bacterial and compounded antibiotic resistance, and dioxin that jeopardizes fragile aquatic ecosystems. The study highlights methylene chloride (in some fabric cleaners), nitrobenzene (soaps, polishes), perfluorinated compounds (stainresistant, waterproof coatings), phthalates (surfactants), alkylphenols (solvents), parabens (preservatives), triclosan, and polycyclic musks (fragrance) as ingredients of concern. Past […]

(Beyond Pesticides, July 6, 2010) A review report published last Friday highlights that some research studies indicate that pesticide exposure either prior to conception, during pregnancy or during childhood appears to increase the risk of childhood cancer, with maternal pesticide exposure during pregnancy being most consistently associated with childhood cancer. Furthermore, the report notes that several studies indicate that farmers are at greater risk of developing certain cancers than the general population. In particular, several studies strongly suggest that pesticide exposures are associated with some cases of non-Hodgkin’s lymphoma (NHL), leukemia, prostate cancer and other hormone related cancers. The report, A Review of the Role Pesticides Play in Some Cancers: Children, farmers and pesticide users at risk?, is published by the United Kingdom organization CHEM (Chemicals, Health and Environment Monitoring) Trust. “Pesticide exposures may interact with other chemical exposures and genetic factors, to cause cancer. Research suggests that pregnant women, in particular, should avoid direct exposure to pesticides, if possible,” said Gwynne Lyons, Director of CHEM Trust and report co-author. “It is high time that the UK was more supportive of EU proposals to take a tougher approach to reducing exposure to potentially harmful chemicals. If the UK is to […]

(Beyond Pesticides, May 11, 2010) Even with the growing body of evidence linking environmental exposures to cancer in recent years, a report released May 6, 2010 by the President’s Cancer Panel finds that the true burden of environmentally-induced cancer is greatly underestimated. The Panel’s report, Reducing Environmental Cancer Risk: What We Can Do Now, concludes that while environmental exposure is not a new front on the war on cancer, the grievous harm from this group of carcinogens has not been addressed adequately by the nation’s cancer program. “There remains a great deal to be done to identify the many existing but unrecognized environmental carcinogens and eliminate those that are known from our daily lives — our workplaces, schools and homes,” said LaSalle D. Leffall, Jr., M.D., chair of the Panel. “The increasing number of known or suspected environmental carcinogens compels us to action, even though we may currently lack irrefutable proof of harm,” he added. Beyond Pesticides applauds the chairman’s precautionary approach and encourages President Obama to heed the panel’s call to “use the power of your office to remove the carcinogens and other toxins from our food, water, and air that needlessly increase health care costs, cripple our Nation’s […]

(Beyond Pesticides, April 12, 2010) Environmental, public health, labor and farmworker advocacy organizations from across the country have filed a petition asking the U.S. Environmental Protection Agency (EPA) to rescind the Bush administration era approval of the highly toxic fumigant pesticide methyl iodide in light of troubling new findings uncovered in California studies. The petition was submitted on the birthday of famed farmworker rights advocate Cesar Chavez, who drew national attention to pesticide misuse on grapes in the 1980s. “In 1988, Cesar Chavez again put his life on the line to draw attention to farmworker rights when he protested the use of pesticides with a 36-day, water-only fast,” said Jeannie Economos, Pesticide Safety and Environmental Health Project Coordinator at Farmworker Association of Florida. “Over 20 years later, we should not have to be fighting the same battles. Methyl iodide use takes us in the dead wrong direction for workers, public health and the future of agriculture.” The movement to ban methyl iodide follows the legacy of Cesar Chavez: the pesticide poses significant, direct risks to farmworkers, their families and neighboring communities. Methyl iodide is a water contaminant, nervous system poison, thyroid toxicant and is listed on California’s Proposition 65 list […]

(Beyond Pesticides, April 1, 2010) While most previous literature on melanoma has focused on host factors and sun exposure, new research shows a link between several pesticides and this deadly form of skin cancer. Epidemiologists from University of Iowa, the National Institute of Environmental Health Sciences and National Cancer Institute found that agricultural workers who apply certain pesticides to farm fields are twice as likely to contract melanoma, providing support for the hypotheses that agricultural chemicals may be another important source of skin cancer risk. The study, “Pesticide use and cutaneous melanoma in pesticide applicators in the Agricultural Heath Study” was published last month in the journal Environmental Health Perspectives. It examines cancer rates in 56,285 pesticide applicators in Iowa and North Carolina as part of the federal government’s Agricultural Health Study, a large, long-term study of pesticide applicators and their spouses. Researchers asked the pesticide applicators how often they were exposed to 50 pesticides and compared their cancer rates. Each person’s exposure was then approximated by adding up the total days that the workers had been exposed and using information from survey results on how the chemicals were applied and what protective equipment was being used. The pesticides that […]

(Beyond Pesticides, July 29, 2009) A new study by researchers at the Lombardi Comprehensive Cancer Center at Georgetown University finds a higher level of common household pesticides in the urine of children with acute lymphoblastic leukemia (ALL), a cancer that develops most commonly between three and seven years of age. The findings are published in the August issue of the journal Therapeutic Drug Monitoring. Researchers, in the study entitled, “Pediatric Acute Lymphoblastic Leukemia and Exposure to Pesticides,” caution that these findings, which do not establish a cause-and-effect relationship, suggest an association between pesticide exposure and development of childhood ALL. “In our study, we compared urine samples from children with ALL and their mothers with healthy children and their moms. We found elevated levels of common household pesticides more often in the mother-child pairs affected by cancer,” says the study’s lead investigator, Offie Soldin, Ph.D., an epidemiologist at Lombardi. Dr. Soldin cautions, “We shouldn’t assume that pesticides caused these cancers, but our findings certainly support the need for more robust research in this area.” Previous studies have found that exposures to certain pesticides increases the risk of developing certain cancers and degenerative diseases. The study was conducted between January 2005 and […]

(Beyond Pesticides, June 16, 2009) A study involving 678 individuals who apply pesticides, culled from a U.S. Agricultural Health Study of over 50,000 farmers, recently found that exposure to certain pesticides doubles one’s risk of developing an abnormal blood condition called MGUS (monoclonal gammopathy of undetermined significance) compared with individuals in the general population. The disorder, characterized by an abnormal level of a plasma protein, requires lifelong monitoring as it is a pre-cancerous condition that can lead to multiple myeloma, a painful cancer of the plasma cells in the bone marrow. The study will appear in the June 18 issue of Blood, the official journal of the American Society of Hematology. “Our study is the first to show an association between pesticide exposure and an excess prevalence of MGUS,” said lead author Ola Landgren, M.D., Ph.D., of the National Cancer Institute (NCI), which is part of the National Institutes of Health, U.S. Department of Health and Human Services. “This finding is particularly important given that we recently found in a large prospective cancer screening study that virtually all multiple myeloma patients experienced a MGUS state prior to developing myeloma.” “As several million Americans use pesticides, it’s important that the risks […]

(Beyond Pesticides, May 28, 2009) Two commonly used herbicides, pendimethalin and EPTC, show a statistically significant exposure-response association with pancreatic cancer. The new study, “Agricultural Pesticide Use And Pancreatic Cancer Risk In The Agricultural Health Study Cohort,” published earlier this month in the International Journal of Cancer, is a case-control study of pesticide applicators and their spouses in Iowa and North Carolina. After controlling for age, smoking and diabetes, the study finds a three-fold increased risk with lifetime pendimethalin use and a two-and-a-half-fold increased risk with lifetime use of EPTC when compared to those that never used the chemicals. Among the 24 pesticides examined, having ever used one of five pesticides (trifluralin, chlorimuron-ethyl, pendimethalin, EPTC or heptachlor) shows at least a 40 percent excess risk of pancreatic cancer. According to the U.S. EPA’s pesticide sales and usage statistics, pendimethalin is the third most commonly used home and garden (and other non-agricultural use) herbicide and the 7th most commonly used herbicide in agriculture, totaling 21-30 million pounds applied annually in the U.S. Pendimethalin is listed by the U.S. EPA as a Group C – Possible Human Carcinogen and is a suspected endocrine disruptor. Pendimethalin has been found to cause central nervous […]

(Beyond Pesticides, January 5, 2009) According to a new study published December 2008 in the online edition of Environmental Health Perspectives, hexavalent chromium (or chromium VI) found in the wood preservatives chromated copper arsenate (CCA) and acid copper chromate (ACC), is a human carcinogen following chronic oral exposure. Previous studies have shown that hexavalent chromium compounds can increase the risk of lung cancer via inhalation exposure. Chromium VI is the notorious chemical that caused cancer in the residents of Hinkley, CA and brought to light by the work of Erin Brockovich. The National Toxicology Program (NTP) conducted 2-year drinking water studies of chromium VI (as sodium dichromate dihydrate) in male and female F344/N rats and B6C3F1 mice. Exposure resulted in increased incidences of rare neoplasms of the squamous epithelium that lines the oral cavity (oral mucosa and tongue) in male and female rats, and of the epithelium lining the small intestine in male and female mice. The authors determined that chromium Vi is carcinogenic following administration in drinking water to male and female rats and mice. The International Agency for Research on Cancer (IARC), the U.S. Department of Health and Human Services, and the Environmental Protection Agency (EPA) each have […]

(Beyond Pesticides, November 13, 2008) The Canadian Cancer Society is holding a conference to look at the possibility of advocating for stricter farm pesticide laws. The Cancer Society has been a vocal advocate for the cosmetic pesticide restrictions that have passed in the provinces of Ontario and Quebec as well as many municipalities, but it has not yet taken a stance on the much larger use of agricultural pesticides. Health Canada, the Canadian entity responsible for pesticide regulation insists, as the U.S. Environmental Protection Agency does in the U.S., that registered pesticides do not pose a substantive health risk when used as directed, but mounting scientific evidence shows otherwise. Many of the same chemicals that Canadian provinces have banned for cosmetic use, such as the herbicide 2,4-D, are used in much higher volumes in agriculture than on lawns. Since the Cancer Society is a strong voice in favor of the cosmetic pesticide bans because of the dangers of pesticides, it is logical that they would also be concerned about agricultural pesticide use. In other words, “It’s very hard to argue that the cosmetic use of pesticides poses a public-health risk, including cancer risk, and not examine what is going on […]

(Beyond Pesticides, October 14, 2008) Exposure to glyphosate or MCPA can more than double one’s risk of developing non-Hodgkin lymphoma (NHL), according to a new epidemiological study published in the October issue of the International Journal of Cancer. The case-control study finds a 2.02 odds ratio (OR) for exposure (two times the chance of contracting the illness) to glyphosate, a 2.81 OR for exposure to MCPA, and a 1.72 OR for exposure to herbicides. According to EPA, glyphosate is the most commonly used pesticide in the U.S. with 103 to 113 million pounds used annually. MCPA is a phenoxyacetic acid pesticide, a family of pesticides that has previously been linked to cancer and includes 2,4-D and mecoprop (MCPP). NHL is a cancer of the immune system. There are several different types of NHL, which are differentiated by the type of immune cell that is cancerous, the characteristics of the cancerous cell, and different genetic mutations of the cancerous cells. Treatment for NHL varies depending on NHL type, patient age, and other existing medical conditions. The incidence of NHL has been increasing over the past several decades. The link between pesticides and cancer has long been a concern. While agriculture has […]

(Beyond Pesticides, October 10, 2008) A study published in the American Journal of Epidemiology [Vol. 167, No. 8] finds women who have used herbicides are twice as likely to have meningioma, a specific kind of brain tumor. The study, “Occupational exposure to pesticides and risk of adult brain tumors,” was conducted by the National Cancer Institute. The authors examined the risk of two types of brain cancer, glioma and meningioma, associated with occupational exposure to insecticides and herbicides in a hospital-based, case-control study of brain cancer. Cases were 462 glioma and 195 meningioma patients diagnosed between 1994 and 1998 in three U.S. hospitals. Controls were 765 patients admitted to the same hospitals for nonmalignant conditions. Occupational histories were collected during personal interviews. Exposure to pesticides was estimated by use of a questionnaire, combined with pesticide measurement data abstracted from published sources. The researchers found no overall link between brain cancer and on-the-job exposure to pesticides or herbicides. However, looking closer at the data, the researchers noticed that women who reported using herbicides had a more than doubled risk for meningioma compared with women who never used herbicides, and there were significant trends of increasing risk with increasing years of herbicide […]

(Beyond Pesticides, August 8, 2008) University of California Davis Cancer Center physicians recently released results of research showing that Vietnam War veterans exposed to Agent Orange have greatly increased risks of prostate cancer and even greater risks of getting the most aggressive form of the disease as compared to those who were not exposed. The findings, which appear online now and will be published in the September 15 issue of the journal Cancer, are the first to reliably link the herbicide with this form of cancer by studying a large population of men in their 60s and the prostate-specific antigen (PSA) test to screen for the disease. “While others have linked Agent Orange to cancers such as soft-tissue sarcomas, Hodgkin’s disease and non-Hodgkin’s lymphoma, there is limited evidence so far associating it with prostate cancer,” said Karim Chamie, lead author of the study and resident physician with the UC Davis Department of Urology and the VA Northern California Health Care System. “Here we report on the largest study to date of Vietnam War veterans exposed to Agent Orange and the incidence of prostate cancer.” Chamie also said that, unlike previous studies that were either too small or conducted on men […]

(Beyond Pesticides, February 13, 2008) The publication of a federal study undertaken by the Centers for Disease and Control (CDC) has been blocked for more than seven months because it contains “alarming information” of evidence of elevated infant mortality and cancer rates in the region surrounding the Great Lakes.The report entitled, Public Health Implications of Hazardous Substances in the Twenty-Six U.S. Great Lakes Areas of Concern, was commissioned by the International Joint Commission (IJC), an independent organization that advises the U.S. and Canadian governments on the use and quality of boundary waters between the two countries, and compiled by the CDC’s Agency for Toxic Substances and Disease Registry (ATSDR). The report outlines the “areas of concern” in which more than nine million people in major metropolitan areas as Chicago, Cleveland, Detroit, and Milwaukee, face higher health risks from exposure to dioxin, PCBs, pesticides, lead, mercury, or six other hazardous pollutants.Contributors to the report include senior experts from the Environmental Protection Agency, CDC, universities, as well as federal and state researchers. These experts have been reviewing data since 2004 and have found low birth weights, elevated rates of infant mortality and premature births, and elevated death rates from breast cancer, colon […]

(Beyond Pesticides, February 7, 2008) The U.S. Environmental Protection Agency (EPA) has awarded more than $500,000 in federal grant funds to several states and non-profit organizations to be used for programs to educate health care providers and women of childbearing age on environmental health risks.The grants were provided to five states and non-profit organizations in Ohio, Michigan, Oregon, Florida, and Texas, and are to focus on educating women, especially pregnant women, on the hazards of environmental contaminants and hazards to children. Health issues such as exposure to mercury, lead, environmental tobacco smoke, chemicals, pesticides, drinking water contaminants, and indoor and outdoor air contaminants have been especially targeted. These grants are estimated to benefit 3,000 health care providers and 10,000 women of childbearing age.“We’re giving pregnant women information on how to avoid exposure to certain environmental hazards to give children a healthy start to life,” said Dona Deleon, acting director, Office of Children’s Health Protection and Environmental Education. “These grants help the public health community reach women during this important time in their lives.”According to the EPA, pregnancy is a time for joy and celebration, but it is also a time to be especially careful about the environment in which one […]