(Beyond Pesticides, February 4, 2009) A new test for triclosan, developed by researchers at the U.S. Department of Agriculture’s Agricultural Research Service (ARS), could help to expedite environmental monitoring of this widely used antibacterial chemical which has been found at high concentrations in rivers and other water resources. Triclosan is linked to a range of health and environmental effects, from skin irritation, bacterial resistance and endocrine disruption, to dioxin contamination and adverse impacts on fragile aquatic ecosystems. The new test called “magnetic particle enzyme immunoassay,” can detect triclosan at a concentration of 20 parts per trillion (ppt)-the equivalent of 1 ounce in 31 million tons. The research team at ARS evaluated the test by using it to detect triclosan and its derivative, methyl-triclosan, in river water, tap water and sewage samples from three municipal plants. They were able to detect triclosan below 20 ppt (the detection limit), indicating very low levels of triclosan in the collected samples. ARS chemist, Weilin L. Shelver, at the ARS Animal Metabolism-Agricultural Chemicals Research Unit in Fargo, N.D., developed the new triclosan test in collaboration with Jennifer Church, Lisa Kamp and Fernando Rubio, a research team at Abraxis, Inc., of Warminster, Pa. Ms. Shelver says […]

(Beyond Pesticides, February 3, 2009) A corporate tomato grower faces an unprecedented penalty of more than $931,000 for misusing pesticides and jeopardizing the health and safety of workers in its New Jersey farm fields and packing houses, New Jersey Department of Environmental Protection (DEP) Acting Commissioner Mark N. Mauriello announced January 30, 2009. In its enforcement action, the DEP cites Ag-Mart Produce Inc., headquartered in Cedarville, Cumberland County, with hundreds of violations that include denying state environmental inspectors access to facilities, losing track of a highly toxic insecticide, failing to properly ventilate areas during pesticide use, failing to post important pesticide-safety information for workers, careless recordkeeping and using forbidden mixtures of pesticides. Ag-Mart Produce widely markets its tomatoes under the brand name “Santa Sweets,” and employs 700 people throughout 17 farm locations in New Jersey. Ag-Mart also owns and operates other produce farms in North Carolina, Florida and Mexico. “Ag-Mart has repeatedly shown a stunning disregard of laws and regulations intended to protect the workers who harvest their tomatoes, the people who consume them and New Jersey’s environment,” Commissioner Mauriello said. “Ag-Mart’s pesticide violations are the most serious DEP inspectors have ever uncovered. We have imposed a record-high penalty not […]

Beyond Pesticides will hold its 27th National Pesticide Forum, Bridge to an Organic Future: Opportunities for health and the environment, April 3-4, 2009 in Carrboro, NC (next to Chapel Hill and the University of North Carolina). This national environmental conference will include sessions on Pesticides and public health; Organic agriculture; Domestic fair trade; Organic lawns and landscapes; Healthy schools and daycare; Water contamination; and much more. Register online or call 202-543-5450 to register by phone. This national environmental conference, co-convened by Toxic Free North Carolina, is an important opportunity for community people nationwide to get together, share the latest information, meet with scientists and policy makers, and discuss local, statewide and national strategies on pest issues, pesticides, public health and the environment. As the home of the National Institute of Environmental Health Sciences (NIEHS) and recently named “America’s Foodiest Small Town,” the location is just the right place for participants to discuss fair, organic food and the impact of pesticides on public health. Keynote speakers for the conference include: Just added! Baldemar Velásquez, president of the Farm Labor Organizing Committee (FLOC), was raised as a migrant farmworker. Since his childhood, he has worked in the fields and orchards of many […]

(Beyond Pesticides, January 28, 2009) The U.S. Environmental Protection Agency’s (EPA) national sewage sludge survey identifies high concentrations of toxic contaminants with heavy metals, steroids and pharmaceuticals, including the antibacterials, triclocarban and triclosan. Despite the prevalence of these toxic chemicals in the environment and their potential adverse impacts to human health and the environment, EPA maintains that it is not appropriate to speculate on the significance of the results at this time. Under the Clean Water Act (CWA), Section 405(d) stipulates that EPA must identify and regulate toxic pollutants that may be present in biosolids (sewage sludge) at levels of concern for public health and the environment. The survey, “Targeted National Sewage Sludge Survey” (TNSSS), sampled 74 selected waste water treatment plants in 35 states during 2006 to 2007. The survey, like its three predecessors, is conducted to determine which chemicals are present in sewage sludge and develop national estimates of their concentrations in order to assess whether exposures may be occurring and whether concentrations found may be of concern. The agency conducted analysis of sewage sludge samples for 145 compounds, including four anions (nitrite/nitrate, fluoride, water-extractable phosphorus), 28 metals, four polycyclic aromatic hydrocarbons, two semi-volatiles, 11 flame retardants, 72 […]

Transforming Government’s Approach to Regulating Pesticides to Protect Public Health and the Environment is a document drafted by Beyond Pesticides and Pesticide Action Network North America that captures grassroots pesticide priorities for the Obama Administration. While we have already submitted these priorities to the Obama transition team, we ask for your support and suggestions because we will continue to use this document as we begin to work with the new administration. To sign on to the document, follow the link above and include your name, organization/company affiliation (if any), city and state in the comment field. The document identifies what the Obama administration can/should take on under existing authority/statutory responsibility, with a specific focus on the first 100 days. Most of the comments in our document focus on pending regulatory actions and pending petitions before the government, either because of ongoing chemical reviews, pending rulemaking, or petitions. While we incorporate big picture thinking, we are focused on specific actions that the relevant agencies could take now. We plan to meet and communicate with the Obama administration to put these suggested actions in place. Issues covered in the document include, but are not limited to: Promoting organic agriculture; Protecting sensitive species; […]

(Beyond Pesticides, January 26, 2009) University of California at Irvine researchers have discovered that sulfuryl fluoride, an insecticide widely used to fumigate termite-infested homes and buildings, stays in the atmosphere at least 30-40 years and perhaps as long as 100 years and is about 4,000 times more efficient than carbon dioxide at trapping heat, though much less of it exists in the atmosphere. This raises concerns as levels have nearly doubled in just the last six years. Prior studies estimated its atmospheric lifetime at as low as five years, grossly underestimating the global warming potential. “Sulfuryl fluoride has a long enough lifetime in the atmosphere that we cannot just close our eyes,” said Mads Sulbaek Andersen, a postdoctoral researcher in the Rowland-Blake laboratory and lead author of the study. “The level in the atmosphere is rising fast, and it doesn’t seem to disappear very quickly.” Its climate impact in California each year equals that of carbon dioxide emitted from about one million vehicles. About 60 percent of the world’s sulfuryl fluoride use occurs in California. The insecticide is pumped into a tent that covers a termite-infested structure. When the tent is removed, the compound escapes into the atmosphere. Sulfuryl fluoride […]

(Beyond Pesticides, January 23, 2009) A study by researchers at the UC Davis M.I.N.D. Institute has found that the seven- to eight-fold increase in the number children born in California with autism since 1990, a trend which shows no sign of abating, cannot be explained by either changes in how the condition is diagnosed or counted, and that environmental factors must be looked at more closely. Published in the January 2009 issue of the journal Epidemiology, the study is entitled “The Rise in Autism and the Role of Age at Diagnosis.” Results from the study suggest that research should shift from genetics to the host of chemicals and infectious microbes in the environment that are likely at the root of changes in the neurodevelopment of California’s children, including pesticides and household chemicals. “It’s time to start looking for the environmental culprits responsible for the remarkable increase in the rate of autism in California,” said UC Davis M.I.N.D. Institute researcher Irva Hertz-Picciotto, PhD, a professor of environmental and occupational health and epidemiology and an internationally respected autism researcher. Dr. Hertz-Picciotto said that many researchers, state officials and advocacy organizations have viewed the rise in autism’s incidence in California with skepticism. The […]

(Beyond Pesticides, January 22, 2009) A new English study has found that chemicals found in rivers and waste waters could be linked to male infertility. These chemicals, known as anti-androgens, block the action of the male sex-hormone testosterone and could impact the development of male reproductive organs in humans. The study entitled, “Statistical Modeling Suggests That Anti-Androgens in Wastewater Treatment Works Effluents Are Contributing Causes of Widespread Sexual Disruption in Fish Living in English Rivers,” and published in the journal Environmental Health and Perspectives identifies a group of river pollutants that cause testosterone to stop working. These chemicals, released from wastewater treatment operations into rivers and other surface waters are responsible for the feminization of male fish and abnormalities in male reproductive organs. Previous studies have attributed these problems in male fish to estrogenic compounds also found in surface waters. However, this study is the first to identify anti-androgens with the feminization of male fish. It also indicates that male feminization may be the result of a rather more complicated interaction taking place between different classes of pollutants, resulting in an endocrine disrupting chemical cocktail. “We have identified a new group of chemicals in our study on fish, but we […]

(Beyond Pesticides, January 21, 2009) Without federal legislation mandating schools adopt safer pest management strategies, around 75% of U.S. schools continue to use hazardous pesticides. As a result, a diverse group of school pest management stakeholders have developed a new document, Pest Management Strategic Plan for IPM in Schools, that they hope will help reinvigorate the adoption of Integrated Pest Management (IPM) programs, aiming for full implementation in all U.S. schools by 2015. The school IPM PSMP document is an in-depth look at the current status of school IPM, specific pest management strategies for schools to use, and actions and timelines for a coordinated effort to getting all schools adopt an IPM program. The strategic plan hinges on garnering leaders in school administration, school health, parents, teachers, custodians, food service staff, state agricultural extension staff, regulators, architects, IPM professionals and other interested individuals to help increase awareness and generate a commitment to school IPM. A group of more than 30 professionals, including Beyond Pesticides staff, have been involved in the development process for the school IPM PSMP, in cooperation with the U.S. Department of Agriculture (USDA) IPM Program, the four USDA Regional IPM Centers, and the US Environmental Protection Agency […]

(Beyond Pesticides, January 16, 2009) The first comprehensive look at toxic contamination throughout the Columbia River Basin has been released by the U.S. Environmental Protection Agency. Issued today, the Columbia River Basin State of the River Report for Toxics compiles currently available data about four widespread contaminants in the Basin and identifies the risks they pose to people, fish, and wildlife. The four contaminants are: * Mercury * Dichlorodiphenyltrichloroethane (DDT) and its breakdown products * Polychlorinated biphenyls (PCBs) * Polybrominated diphenyl ether (PBDE) flame retardants. According to Elin Miller, EPA Regional Administrator in Seattle, a team of more than 20 federal and state agencies, Tribes, local governments and organizations teamed-up to draw this latest portrait of the toxic threats faced by the Columbia River Basin, which drains nearly 260,000 square miles across seven U.S. states and a Canadian province. “This is troubling news,” said EPA’s Miller. “Today’s Report shows that toxics are found throughout the Basin at levels that could harm people, fish, and wildlife. Federal, tribal, state, and local efforts have reduced levels of some toxics such as PCBs and DDTs, but in many areas, they continue to pose an unacceptable risk. Tackling this problem will require a coordinated […]

(Beyond Pesticides, January 14, 2009) Two-headed bass found in the Noosa River are at the center of a controversy surrounding pesticide drift from neighboring farms in Queensland, Australia. The pesticides, endosulfan and carbendazim, have been implicated in the contamination of the river, which has yielded thousands of chronically deformed fish. Experts believe that the mutated fish, which survive only 48 hours after hatching, are the victims of pesticide drift from neighboring macadamia nut farms that routinely use endosulfan and the fungicide, carbendazim. Aquatic health expert and vice-president of the Australian College of Veterinarian Scientists’ Aquatic Animal Health Chapter, Matt Landos, PhD, has been investigating the phenomenon and concludes that there were no other probable causes to explain the fish and larval mortality. Dr. Landos documented evidence and completed a report which was sent to the state’s Department of Primary Industries and Fisheries last year. “The timing between the mist spraying and the affected larvae fits hand in glove,” Dr. Landos said. His report also found that chickens, sheep and horses raised at nearby fish hatcheries are also recording abnormally high levels of fetal deaths and birth defects. Gwen Gilson, who runs a Boreen Point fish hatchery, says she has observed […]

(Beyond Pesticides, January 9, 2009) Environmental Toxicology and Chemistry has published a study (Vol. 27(12):2496—2500) entitled “Effects of Malathion on Embryonic Development and Latent Susceptibility to Trematode Parasites in Ranid Tadpoles.” It shows that malathion used as an agricultural insecticide is responsible for interfering with the normal development of pickerel frog embryos, thus leaving them more susceptible to parasite invasion. Malathion is present in natural water sources that have been exposed to urban and agricultural runoff. This organophosphate pesticide can be applied by planes in mosquito control program, and as esult enters water from the air. Although direct lethal and sublethal effects of chemical contaminants have been documented, latent and long-term effects have been less well documented. Therefore, researchers sought to fill this knowledge gap and found, as suspected, that tadpole survival rates decreased and malformations and susceptibility to parasite encystment rates increased as a result of exposure to malathion concentrations mimicking those found in actual water sources. Tadpoles are being exposed to increasing numbers of parasites in waters that are warming as a result of global climate change, and the researchers who performed this study speculate that, as a consequence, those exposed to malathion will have weakened immune systems […]

(Beyond Pesticides, January 5, 2009) According to a new study published December 2008 in the online edition of Environmental Health Perspectives, hexavalent chromium (or chromium VI) found in the wood preservatives chromated copper arsenate (CCA) and acid copper chromate (ACC), is a human carcinogen following chronic oral exposure. Previous studies have shown that hexavalent chromium compounds can increase the risk of lung cancer via inhalation exposure. Chromium VI is the notorious chemical that caused cancer in the residents of Hinkley, CA and brought to light by the work of Erin Brockovich. The National Toxicology Program (NTP) conducted 2-year drinking water studies of chromium VI (as sodium dichromate dihydrate) in male and female F344/N rats and B6C3F1 mice. Exposure resulted in increased incidences of rare neoplasms of the squamous epithelium that lines the oral cavity (oral mucosa and tongue) in male and female rats, and of the epithelium lining the small intestine in male and female mice. The authors determined that chromium Vi is carcinogenic following administration in drinking water to male and female rats and mice. The International Agency for Research on Cancer (IARC), the U.S. Department of Health and Human Services, and the Environmental Protection Agency (EPA) each have […]

(Beyond Pesticides, December 22, 2008) The U.S. EPA has filed an administrative complaint, seeking a maximum penalty of only $4,550, against a pest control company that sprayed pesticides in a couple’s home, causing the wife to die shortly thereafter. It has been more than three years since the incident took place in Florence, Oregon. Swanson’s Pest Management of Eugene, Oregon sent an employee to a home on June 29, 2005 to apply Conquer Residential Insecticide Concentrate, active ingredient esfenvalerate, and ULD BP-100 Contact Insecticide, active ingredient pyrethrin. The couple returned to their home two and a half hours later and immediately fell to the ground due to the fumes. Paramedics were called in and they too experienced respiratory distress or became ill when they entered the treated home. According to The Oregonian, Florence Kolbeck was 76 years old and died of cardiac arrest as a result of the exposure. Her husband, Fred, was hospitalized for respiratory distress. The complaint was filed following a review of Swanson’s use of the two pesticides, finding that the company failed to properly ventilate the home prior to the occupants re-entering, and improperly applied Conquer as a “space spray” at nearly three times the allowable […]

(Beyond Pesticides, December 19, 2008) In resopnse to an Environmental Protection Agency (EPA) published final Reregistration Eligibility Decision (RED) document for triclosan (October 29, 2008), groups are citing a serious lack of health and environmental protection and the agency’s failure to meet its statutory duty. Formal comments will be submitted to the agency during a comment period that ends at the end of December 2008. Groups have been invited to sign a joint statement. Triclosan is a synthetic, broad-spectrum antimicrobial agent that in recent years has exploded onto the consumer market in a wide variety of antibacterial soaps, deodorants, toothpastes, cosmetics, fabrics, plastics, and other products. Studies link triclosan to a range of health and environmental effects, from skin irritation, allergy susceptibility, bacterial and compounded antibiotic resistant, and dioxin contamination to destruction of fragile aquatic ecosystems. Many of Beyond Pesticides comments that were submitted on July 7, 2008 were considered and amendments were made to the risk assessment. However, despite many lingering issues related to triclosan continued threat to human and environmental health, the agency concluded that triclosan was eligible for reregistration. This means that the continued and expanding use of this chlorinated, bioaccumulative pesticide, with the ability to produce […]

(Beyond Pesticides, December 18, 2008) The New Zealand’s Environmental Risk Management Authority (ERMA) has announced it will ban the controversial organochlorine pesticide endosulfan, effective January 16, 2009. Endosulfan, already banned in numerous countries including all the European Union countries, is an insecticide used on a wide range of fruits and vegetables and also on athletic fields in New Zealand. Illegal residues have been found in beef destined for South Korea, resulting in enormous costs for New Zealand exporters. Use of endosulfan for agriculture continues in the U.S., despite causing severe health and environmental problems. A coalition of groups, including the Pesticide Action Network Aotearoa New Zealand (PAN ANZ), Soil and Health Association and Safe Food Campaign, have long campaigned for the banning of endosulfan. Earlier this year, the three organizations carried out a number of residue tests on produce to draw attention to the extent of endosulfan residues, especially in tomatoes. “We are delighted that ERMA has overturned its earlier ”˜proposed’ decision to keep using this pesticide,” stated Meriel Watts, Ph.D., co-coordinator of PAN ANZ. “It would have been deeply embarrassing for New Zealand to continue its use when the pesticide has entered the process for a global ban under […]

(Beyond Pesticides, December 16, 2008) According to a new study, published in the December 2008 issue of Environmental Health Perspectives by researchers at Columbia University’s Mailman School of Public Health, pregnant women continue to be exposed to pesticides in the home. In fact, 75% of the sampled homes of pregnant women in inner-city New York are contaminated with piperonyl butoxide (PBO), a pesticide synergist linked to cancer and other health problems. Following the Environmental Protection Agency’s phase-out agreements with the manufacturers of organophosphate insecticides chlorpyrifos and diazinon in 2000 and 2001, the Columbia University researchers sought to determine the impact of the new regulations on pest infestation levels, pesticide use, and pesticides measured in indoor air samples. They enrolled 511 pregnant women from inner-city New York between 2000 and 2006. Permethrin, a pyrethroid insecticide; PBO, a pyrethroid synergist; chlorpyrifos; and diazinon were measured in 48-hr prenatal personal air samples. Data on pest infestation and pesticide use were collected via questionnaire. 88% of women report using pesticides during pregnancy and 55% report using higher-exposure pesticide applications (spray cans, pest bombs and/or professional pesticide applicators). Self-reported pest sightings and use of higher-exposure applications increased significantly after the regulations were implemented. PBO, cis-, […]

(Beyond Pesticides, December 12, 2008) A new study has found pesticides in surface waters around the United States. The U.S. Geological Survey (USGS) analyzed water from nine selected rivers, which are used as a source for public water systems and found that low levels of certain xynthetic chemicals remain in public water supplies after being treated in selected community water facilities. “Most of the man-made chemicals assessed in the USGS study are unregulated in drinking water and not required to be monitored or removed,” says Tom Jacobus, General Manager of the Washington Aqueduct. “These findings are not surprising and they will be important in helping regulators and assisting water utility managers arrive at decisions about future water treatment processes.” Scientists tested water samples for about 260 commonly used chemicals, including pesticides, solvents, gasoline hydrocarbons, personal care and household-use products, disinfection by-products, and manufacturing additives. This study did not look at pharmaceuticals or hormones. Low levels of about 130 of the synthetic chemicals are detected in streams and rivers before treatment at the public water facilities (source water). Nearly two-thirds of these chemicals are also detected after treatment. Most of the chemicals found are at levels equivalent to one thimble of […]

(Beyond Pesticides, December 11, 2008) In a recent study, researchers find that triclosan, the antibacterial agent found in many consumer products including soaps, toothpaste, cosmetics, counter tops and toys, alters thyroid function in male rats. These effects are observed at concentrations that may be used in consumer products and highlight the growing threat consumers face from this hazardous and ubiquitous chemical. The study, entitled, “The effects of triclosan on puberty and thyroid hormones in male wistar rats,” was reviewed by the National Health and Environmental Effects Research Laboratory, the U.S. Environmental Protection Agency (EPA) and approved for publication in Toxicological Sciences. Researchers measured blood concentrations of testosterone and several other types of hormones and weighed a variety of organs that are essential for rat development and puberty, including the pituitary gland, the testes, the prostate gland and the liver of male rat pups fed an oral dose of triclosan for 31 days. The purpose of the experiment was to determine what effects triclosan would have on concentrations of thyroid hormones and the onset of puberty. Results show a dramatic decrease in the thyroid hormone -thyroxine in rats exposed to increasing concentrations of triclosan, as well as significant increases in liver […]

(Beyond Pesticides, December 10, 2008) Most families don’t realize that they might be bringing more than holiday cheer into their homes this Christmas season. Families celebrating this holiday season with the time-honored tradition of a Christmas tree can choose to go green and avoid the toxic chemicals that are typically used to grow it. Beyond Pesticides recently launched a Christmas Trees and Pesticides web page to help inform consumers this holiday season. Of the pesticides that the Environmental Protection Agency (EPA) has registered for use on Christmas trees, most are linked to one or more adverse effects, including cancer, hormonal disruption, neurotoxicity, organ damage, reproductive/birth defects, asthma, environmental effects and more. Their use results in exposure to workers, wildlife, and waterways. Beyond Pesticides has compiled a list of 25 pesticides commonly used or recommended for use by state agricultural extension services, including: 2,4-D, bifenthrin, chlorpyrifos, diazinon, esfenvalerate, glyphosate, simazine and more. Oregon, North Carolina, Michigan, Pennsylvania, Wisconsin, Washington, New York, and Virginia are the nation’s top Christmas tree producing states, and together account for more than half of the trees grown in the U.S. The Cooperative Extension Service of North Carolina reports that glyphosate -a pesticide linked to increased risk […]

(Beyond Pesticides, December 8, 2008) A new study by a National Institute for Occupational Safety and Health (NIOSH) researcher finds the pesticide poisoning incidence rate among U.S. agricultural workers is thirty-nine times higher than the incidence rate found in all other industries combined. The study, “Acute Pesticide Poisoning Among Agricultural Workers in the United Sates, 1998-2005,” published in the December issue of the American Journal of Industrial Medicine, is believed to be the first detailed multi-state assessment of acute pesticide poisonings among agricultural workers. From 1998 to 2005, a total of 3,271 cases of acute occupational pesticide-related illness/injury among agricultural workers were identified in ten states. According to EPA, the Worker Protection Standards are designed to reduce the risk of injury or illness to agricultural field workers resulting from exposure to pesticides. Although the WPS was expanded in 1995 and in 2005 EPA developed a new WPS How to Comply (HTC) Manual, the NIOSH findings indicate that agricultural workers continue to have an elevated risk for acute pesticide poisoning. Furthermore, female agricultural workers experienced nearly twice the risk of pesticide poisoning of male agricultural workers. The most common factors that contributed to pesticide exposure included off-target drift, early reentry into […]

(Beyond Pesticides, December 5, 2009) On November 10, 2008, the Austrian government released a report of long term research showing genetically engineered (GE) corn fed to mice significantly reduced their fertility over three to four breeding cycles within one generation. Similar effects were found in mice fed GE corn and bred over four generations. The study, “Biological effects of transgenic maize NK603xMON810 fed in long term reproduction studies in mice,” was sponsored by the Austrian Ministry of Health, Families, and Youth, and led by Dr. Jürgen Zentek, Professor of Veterinary Medicine at the University of Vienna. Three series of experiments were done. The first was a multigeneration feeding trial in which the mice were fed and bred for four successive generations, beginning with the parents that were fed the diets from birth. The second was a multi-cycle breeding trial lasting 20 weeks in which breeding pairs of mice were fed beginning one week prior to co-habitation until the end of experiment, and allowed to go through four breeding cycles in the same generation. The third was a life-term trial involving feeding the mice without breeding from conception (via the pregnant mothers) to their eventual death. The researchers report that it […]

(Beyond Pesticides, December 2, 2008) Tributyltin (also known as TBT), a ubiquitous pollutant that has a potent effect on gene activity, could be promoting obesity, according to an article in the December issue of BioScience, the journal of the American Institute of Biological Sciences. The chemical is used in antifouling paints for boats, as a wood and textile preservative, and as a pesticide on high-value food crops, among many other applications. Tributyltin affects sensitive receptors in the cells of animals, from water fleas to humans, at very low concentrations–a thousand times lower than pollutants that are known to interfere with sexual development of wildlife species. Tributyltin and its relatives are highly toxic to mollusks, causing female snails to develop male sexual characteristics, and it bioaccumulates in fish and shellfish. Recent research has found it in deep-sea squids and octopods, and it has been banned for maritime use by an international treaty. The harmful effects of the chemical on the liver and the nervous and immune systems in mammals are well known, but its powerful effects on the cellular components known as retinoid X receptors (RXRs) in a range of species are a recent discovery. When activated, RXRs can migrate into […]