(Beyond Pesticides, April 29, 2009) The U.S. Environmental Protection Agency (EPA) announced earlier this month that it is finally ready to move forward with preliminary testing of 67 active and inert pesticide ingredients for possible endocrine disrupting effects. But, according to prominent researcher and author Theo Colborn, PhD, these tests are outdated, insensitive, crude, and narrowly limited, and will fail to detect many serious effects on human development. In an eye-opening opinion-editorial published in Environmental Health News, Dr. Colborn, founder and president of The Endocrine Disruption Exchange, and Co-author of Stolen Future, says that EPA’s testing protocol is “a pitiful skeleton” of what it needs to be. The tests to be used by EPA were first recommended in 1998. Since then the science has made progress and become more sophisticated. Current research is based on different assumptions than the toxicological assumptions that first drove the EPA test designs. However, EPA has not updated its protocol. Each of EPA’s tests and assays was designed under the surveillance of corporate lawyers who had bottom lines to protect and assorted toxicologists who were not trained in endocrinology and developmental biology. For over a decade, EPA ignored the vast wealth of information on endocrine […]

(Beyond Pesticides, April 17, 2009) Thirteen years after the Food Quality Protection Act (FQPA) ordered EPA to develop a screening process for endocrine disrupting chemicals, the Environmental Protection Agency (EPA) has released a final list of chemicals to be included in Tier 1 testing for endocrine disrupting effects of pesticides in use. While the list has been reduced from the 73 chemicals announced two years ago, trials will begin this summer to determine human risk from some of the chemicals to which we are most commonly exposed. “Endocrine disruptors can cause lifelong health problems, especially for children,” stated EPA Administrator Lisa Jackson. “Gathering this information will help us work with communities and industry to protect Americans from harmful exposure.” EPA’s recent announcement of these chemicals can be found on EPA’s Endocrine Disruptor Screening Program (EDSP) page. According to EPA, “The Agency deleted 6 chemicals from the draft list of 73 based upon recent information showing that the chemicals are no longer expected to be found in 3 exposure pathways.” To be included on the initial list, EPA established that chemicals need to be found in three of EPA’s four exposure pathways: food, drinking water, residential use, and occupational exposure. Azinphos-methyl […]

(Beyond Pesticides, February 19, 2009) The Endocrine Exchange (TEDX) has released a new database on the prenatal origins of endocrine disruption, called Critical Windows of Development. It compares human development in the womb with laboratory research showing where and when low-dose exposures to chemicals have effects. The timeline currently charts three chemicals: dioxin, bisphenol A (BPA), and phthalates. TEDX plans to expand the database to include PCBs, PBDEs, DDT, and other endocrine-disrupting pesticides. Examples of conclusions from the prenatal exposure research include: BPA affects development of the male and female reproductive systems, increases susceptibility to breast cancer and alters behavior in adult animals; Phthalates decrease sperm production and increase body weight; and, dioxin affects male reproduction and the immune system. Before a baby is born it is exposed to a myriad of endocrine disrupting chemicals (EDCs). EDCs interfere with the delicate system of vital hormones, glands and organs that control how a baby develops and functions throughout life. EDCs such as BPA, dioxin and phthalates can penetrate the womb and cause adverse effects at extremely low exposure levels. These chemicals are found in water bottles, food cans, dental resins, cleaning products, cosmetics, fragrances, packaging and construction material, cars, planes, recreational […]

(Beyond Pesticides, November 7, 2008) The European Parliament’s environment committee has passed new measures aimed at reducing use and toxicity of pesticides used on crops throughout the European Union (EU). If approved by Parliament at the end of the year, the EU will be on its way to reducing pesticide use by 85 percent by 2013. The measure faces significant backlash from the chemical industry and conventional farmers, but committee members (MEPs) remain firm that the restrictions are both important and possible to do. An official report published last month found record levels of pesticide residues on EU food, giving momentum to pesticide restrictions. One adopted regulation will cause a list of approved “active substances” to be drawn up, according to which pesticides will be registered at a national level. It also allows EU states to be stricter than the allowable list. One amendment says, “Member states may establish any pesticide-free zones they deem necessary in order to safeguard drinking water resources. Such pesticide-free zones may cover the entire Member State.” The second approved measure, passed on to Parliament by EU agricultural ministers in June, bans “certain highly toxic chemicals,” those being endocrine disrupting, genotoxic, carcinogenic or toxic to reproduction. […]

(Beyond Pesticides, November 3, 2008) A new study, Pyrethroid pesticides and their metabolites in vacuum cleaner dust collected from homes and day-care centers (doi:10.1016/j.envres.2008.07.022), by the U.S. Environmental Protection Agency’s (EPA) National Exposure Research Laboratory finds concentrations of 13 synthetic pyrethroids and their degradates in indoor dust collected from homes and childcare centers in North Carolina and Ohio. The study results show the extent to which hazardous pesticides are present in indoor environments and threaten the public’s health, especially the health of children. With 85 vacuum cleaner bags analyzed, permethrin was present in all 85 dust samples, at least one pyrethroid pesticide was found in 69 samples and phenothrin was found in 36 samples. According to the study findings published in the November issue of the journal Environmental Research, the median concentration of permethrin in the samples is 1454ng/g of dust. Excluding permethrin, pyrethroid conectrations are less than or equal to 100ng/g of dust. The majority of the metabolites are present in more than half of the dust samples. This is not the first time researchers have found pesticides in dust in homes. A study published in the International Journal of Hygiene and Environmental Health (208: 193-199) also found that […]

(Beyond Pesticides, October 20, 2008) Organophosphate (OP) pesticides are among a toxic soup of hazardous chemicals found in the bodies of pregnant women, according to an National Institutes of Environmental Health Sciences (NIEHS) led study doi:10.1016/j.envres.2008.07.014 published in the October issue of the journal Environmental Research. The population-based birth cohort study analyzed urine specimens of one hundred pregnant women. The study builds on the existing body of evidence that shows that low-level exposure to chemicals impact human health, especially pregnant women and their children. The research is part of the Generation R Study, which includes 9778 participants in the Netherlands and focuses on growth and physical development, behavioral and cognitive development, childhood diseases and health, and health care for pregnant women and children. The Generation R Study allows the researchers to follow-up with the study participants and “provides an opportunity to efficiently address questions regarding the reproductive and development effects of prenatal exposures.” Besides finding high levels of OP pesticides, the researchers find some suspected endocrine disrupting compounds including bisphenol A (BPA) and phthalates. Animal studies show that these chemicals can affect brain and reproductive development. According to the researchers, exposure to OP pesticides and some phthalates were significantly higher […]

(Beyond Pesticides, August 27, 2008) Citing the possibility of lower crop yields and higher food prices, government ministers in the United Kingdom are planning to step up pressure on the European Parliament in opposition to plans to ban the most hazardous pesticides, amounting to three quarters of the pesticides used by farmers in the European Union. Environmental campaigners, like the UK Pesticides Campaign, are adamant that a crackdown on the use of pesticides is needed to protect public health and believe that the new measures must not be watered down by industry lobbying. Officials from the U.K. Department of the Environment, Food and Rural Affairs (DEFRA) believe that the ban would remove important pesticides from the market. Those arguing against the proposal say it could prevent the use of certain fungicides and result in substantially lower wheat yields, postulating a 30 percent reduction from current levels. DEFRA officials claim that the ban would have “significant adverse impact on crop protection, but secure no significant health benefits for consumers.” British Farming Minister Lord Rooker is adamant that fungicides should not be banned before alternatives are approved and is urging other European countries to block the measure. The controversy centers on the […]

(Beyond Pesticides, July 17, 2008) In a new study published in Environmental Health Perspectives, researchers have found an increased occurrence of intersex toads in areas with greater agricultural land cover. This points to a link between certain pesticides and endocrine disruption, a change in the hormonal balance that can have sexual and reproductive effects. Such results implicate pesticides in the decline of amphibian populations, and suggests that these chemicals are also adversely affecting humans. The study, which was conducted in south Florida, looked at cane toads, Bufo marinus, at five sites with differing land use patterns ranging from suburban to nearly completely agricultural (primarily sugarcane and vegetables). Researchers examined physical characteristics such as coloration, sexual organs, and forelimb length, as well as hormone concentrations, and found a higher rate of feminization for toads in agricultural areas. In these areas, glyphosate (the active ingredient in Round Up herbicide) and atrazine (an herbicide) use is common. Tyrone Hayes, PhD, was one of the first to document the endocrine disrupting effects of atrazine on frogs in a laboratory setting. Countering any doubts of why this work is important, Dr. Hayes said, “People often say, ”˜It is just frogs, so who cares?’ Well it […]

(Beyond Pesticides, June 26, 2008) Over 7,500 acres of winter wheat in 15 Kansas counties were sprayed improperly with the fungicide Quilt, forcing the Kansas Department of Agriculture to put an embargo on harvestable wheat from these fields pending further tests. Farmers are legally required to wait 45 days between spraying Quilt and harvesting wheat, but this spring’s wet weather encouraged many to ignore the rules. The problem was discovered during a paperwork check of custom applicators, which revealed that some fields had been sprayed as recently as early June. Quilt, manufactured by Syngenta and registered with the Environmental Protection Agency (EPA) in 2003, is a combination of the two active ingredients azoxystrobin and propiconazole. Propinconazole is a fungicide and antimicrobial with registered uses on food and feed crops, turf and ornamentals, as well as wood and material preservation. It is estimated that 1.7 million acres of wheat alone is treated with propinconazole each year. Azoxystrobin was first conditionally registered with the EPA in 1997 for use on turf. Information on the usage of the combination of these two fungicides is unavailable because of the recent registrations. Unfortunately, the USDA has cut funding for pesticide reporting (see Daily News of […]

(Beyond Pesticides, June 3, 2008) The National Gardening Association’s (NGA) 2008 Environmental Lawn and Garden Survey finds that only one out of five U.S. homeowners chooses lawn and landscape practices classified as “green” by NGA —and the association’s standards were not even very high. To evaluate homeowner lawn care practices, NGA used its “Eco-Scorecard” to ask respondents which of 12 environmentally friendly lawn, garden, and landscape practices they will follow at home this year. Unfortunately, maintaining an organic lawn, didn’t even make the survey. Instead NGA, which partners with companies that manufacture and sell lawn chemicals, asked questions like, “Do you read and follow the label carefully when using pesticides and fertilizers?” 49% said “yes.” Beyond Pesticides has previously told the NGA that label compliance does not adequately protect people, pets and the environment because of deficiencies and limitations in EPA’s pesticide regulatory review process, which is focused on risk assessment calculations that, among other things, ignore the effect of chemical mixtures on lawns, low level exposure, endocrine disrupting effects, and the full range of impacts on children and pets. Beyond Pesticides has urged organizations like NGA to embrace the precautionary principle and the elimination of cosmetic or aesthetic uses […]

(Beyond Pesticides, May 30, 2008) A recent study has linked the common herbicide atrazine with endocrine disruption in both fish and human cells. Entitled “The Herbicide Atrazine Activates Endocrine Gene Networks via Non-Steroidal NR5A Nuclear Receptors in Fish and Mammalian Cells,” the University of Califonia, San Francisco (UCSF) research examines the reaction of zebrafish to environmentally relevant levels of atrazine, and mirrors the study in human placental cells. The zebrafish, which are particularly sensitive to endocrine disruptors,  are “feminized”  in greater proportion than the unexposed control group. Fish exposed to atrazine for 48 hours at levels found in agricultural runoff produced twice as many female fish as male. “These fish are very sensitive to endocrine disrupting chemicals, so one might think of them as ‘sentinels’ to potential developmental dangers in humans,” said senior author Holly Ingraham, PhD. “These atrazine-sensitive genes are central to normal reproduction and are found in steroid producing tissues. You have to wonder about the long-term effects of exposing the rapidly developing fetus to atrazine or other endocrine disruptors.” In human cell studies, the researchers found that atrazine activates genes involved in hormone signally and steroid synthesis. “Endocrine-related cell types with a capacity for steroid generation appear […]

(Beyond Pesticides, April 25, 2008)  The Environmental Protection Agency (EPA) Region 5 this week issued a “stop sale, use or removal” order against Scotts Miracle Gro Co. and three affiliates, all of Marysville, Ohio, for illegal, unregistered and misbranded weed and fertilizer products with a cancer causing and endocrine disrupting pesticide ingredient. EPA will also issue a stop sale order to Scotts Lawn Care Service.Scotts has agreed to recall two products from all retail locations across the United States and to set up a process for consumers to safely return any unregistered products they may have purchased. EPA ordered the companies, collectively an international producer and distributor of lawn care products, to immediately stop selling and distributing the products which can be identified by the invalid “EPA registration number” listed on the package. Invalid registration number 62355-4 is marketed under names including “Garden Weed Preventer + Plant Food” and “Miracle Gro Shake ‘n’ Feed All Purpose Plant Food Plus Weed Preventer.” The active ingredient of this product is trifluralin, an herbicide that is a possible carcinogen and probable endocrine disruptor, among its health effects. Invalid registration number 538-304 is used primarily by Scotts Lawn Service, a lawn care company. It […]

(Beyond Pesticides, April 10, 2008) Common frogs that live in suburban areas are more likely than their rural counterparts to develop reproductive abnormalities, according to David Skelly, PhD, professor of ecology at the Yale School of Forestry and Environmental Studies. This phenomenon becomes a serious concern as the frog’s mating season begins, leaving researchers to wonder: will frogs be clear on their role in the annual ritual? Research by Dr. Skelly, soon to be published, focuses on the common green frog, Rana clamitans, within the Connecticut River Valley. A total of 233 frogs were collected from various ponds and landscapes with the river valley and among them 13 percent have abnormalities occurring in their reproductive organs. In urban areas, 18 percent of the collected frogs are intersex, and in suburban areas 21 percent. Frogs collected from agricultural areas have the lowest rate of reproductive problems with just 7 percent classified as intersex. According to Dr. Skelly, the more suburban the land cover, the more likely the abnormalities. “This is the first evidence that I think anyone has provided that agriculture is doing anything but pushing those rates higher,” remarked Dr. Skelly of the intersex phenomena. In an attempt to explain […]

(Beyond Pesticides, April 7, 2008) A coalition of farmworker advocates and environmental groups filed a lawsuit against the Environmental Protection Agency (EPA) to stop the continued use of four deadly organophosphate pesticides. These pesticides were derived from nerve gas developed during World War II. Some of these pesticides have been detected in California’s rural schoolyards and homes, Sequoia National Park, and Monterey Bay. The four organophosphates at issue in the case filed April 4 are methidathion, oxydemeton-methyl, methamidophos, and ethoprop. They are used primarily in California on a wide variety of fruit, vegetable, and nut crops. “These four pesticides put thousands of farmworkers and their families at risk of serious illness every year,” said Patti Goldman, an attorney for Earthjustice, the environmental law firm that represents the coalition. “It is inexcusable for EPA to allow use of pesticides that they know are harming people, especially children.” EPA has documented that children are especially susceptible to poisoning from organophosphates. Exposure can cause dizziness, vomiting, convulsions, numbness in the limbs, loss of intellectual functioning, and death. Some organophosphates also cause hormone disruption, birth defects, and cancer. “Farmworkers, and all people living in and near agricultural regions, especially children, are at great risk […]

(Beyond Pesticides, March 24, 2008) Scientists at the U.S. Geological Survey (USGS) announced that they have identified ten contaminants, including pesticides, in the Potomac River, which flows through downtown Washington, DC, that could be responsible for the alarming discovery of “intersex fish,” male fish producing eggs. The suspected chemicals include: atrazine, a common herbicide used in agriculture and on lawns that is already linked to sexual abnormalities in frogs; insecticides chlorpyrifos and endosulfan; the herbicide metolachlor; and two chemicals used to add fragrance to perfumes, soaps and other products, tonalide and galaxolide. To collect the samples, USGS scientists suspended a device intended to serve as a facsimile fish in the Potomac River near the Washington, DC’s Blue Plains sewage plant. The device had a plastic-coated tube, which simulated a fish’s permeable skin, and a layer of simulated fat. According to the Washington Post, the tests on this fake fat revealed a range of potentially worrisome pollutants. Most have been found in other streams around the U.S. “The types of things we’re finding are the types of things that are associated with everyday life,” David Alvarez, a U.S. Geological Survey research chemist who analyzed samples from the Potomac told the Washington […]

(Beyond Pesticides, March 20, 2008) A 2000-2005 U.S. Geological Survey (USGS) study, Pesticide Occurrence and Distribution in the Lower Clackamas River Basin, Oregon, 2000-2005, finds a variety of pesticides in river and tributary samples, along with trace-level detections of pesticides in treated drinking-water samples collected from a drinking-water treatment plant that uses the Clackamas River as a raw-water source. While the federal government is quick to point out that detections in drinking water are below existing Environmental Protection Agency (EPA) drinking-water standards and most river samples are below the agency’s aquatic life benchmarks, studies show hazardous endocrine-disrupting and immunosuppressive effects at extremely low levels — far below EPA standards. A total of 63 pesticide compounds were detected in 119 water samples collected during storm and non-storm conditions using low-level detection methods. More pesticides were detected in the tributaries than in the Clackamas River mainstem. One or more of 15 pesticides were detected in nine of 15 samples of drinking water. Environmental and public health advocates are concerned that these results add to a pattern of contamination across the country. USGS data released in 2008, shows widespread pesticide contamination in the Chesapeake Bay watershed, and a 2004 USGS report of nationwide […]

(Beyond Pesticides, March 18, 2008) To kick off National Poison Prevention Week on March 17, the U.S. Environmental Protection Agency (EPA) is urging people to “lock up” their pesticides to protect children —stopping far short of advising the public on non-toxic methods of pest management. According to public health advocates, EPA, as a facilitator and apologist for the unnecessary use of highly toxic pesticides that it registers missed an important opportunity during National Poison Prevention Week to alert families with children about integrated management and organic methods that are effective but not reliant on hazardous methods. “With the wide availability of non-toxic methods and products, there is no reason for people to have poisonous pesticides in their homes and risk their children’s exposure,” said Jay Feldman, executive director of Beyond Pesticides. Despite numerous scientific studies that show children carrying a body burden of pesticides used in homes and elevated rates of childhood cancer in households that use pesticides, given children special vulnerability to pesticides, EPA chose to focus on pesticide poisoning of children associated with accidental ingestion. The agency launched the week with the headline “Play It Safe, Prevent Poisonings, Lock Up Pesticides” and the quote, “The U.S. Environmental Protection […]

(Beyond Pesticides, March 17, 2008) Not everything that goes down the drain can be removed by water treatment plants, which leaves some alarming contaminants in America’s drinking water. A five-month investigation by the Associated Press (AP) finds trace quantities of pharmaceuticals in the drinking water of 41 million Americans. Scientists fear that ingestion of these tiny amounts of drugs may pose health risks to the public, wildlife and aquatic organisms. The AP investigation surveyed the 50 largest cities in the country and a dozen other major water providers, as well as other small providers in each of the 50 states. A wide range of pharmaceuticals, whether administered to humans or to farm animals, are found in the water of 24 major metropolitan areas, and tests done in the watersheds of 35 major water providers shows 28 testing positive for pharmaceuticals. The levels of pharmaceuticals found in the water are at levels measured in the parts per billion or trillion, far below levels of medical use. The federal government has not set safety limits for drugs in drinking water. In fact, fewer than half of the 62 major water providers could say their water was tested. Water treatment plants are not […]

(Beyond Pesticides, February 19, 2008) Common household chemicals and widespread pollutants are changing male reproductive health and impacting sexual function, development and cancer rates of today’s generations and possibly their offspring, according to more than 15 years of research by a Colorado State University expert. For example, one study looking at sperm counts globally from 1940, when chemicals first began to be widely produced, to the 1990s, indicates a 1.15 percent per year decline in sperm counts. These declines may be linked to chemical exposure.Rao Veeramachaneni, BVSc, MScVet, PhD, a biomedical sciences professor in the College of Veterinary Medicine and Biomedical Sciences, has found that chemicals including pesticides, common pollutants in ground water, and chemicals in plastics, make-up and nail polish are on a growing list of culprits causing developmental abnormalities such as impaired sperm quality and impotence. Reproductive health can be compromised if males are exposed at various times in life spanning from in utero up to adulthood.Dr. Veeramachaneni’s findings span the globe and are across species lines, from humans to horses, wildlife to frogs. His research, coupled with the collective findings of other experts in the field, indicates a strong link related to pollutants, and incidence of such […]

(Beyond Pesticides, January 9, 2008) Triclocarban, an antibacterial compound widely used as an additive to a range of household and personal care products including bar soaps, detergents, body washes, cleansing lotions, and wipes, has been found to have an amplification effect on the activity of natural hormones, which in turn can lead to adverse reproductive and developmental effects. In the study, published online November 29, 2007 in Endocrinology, researchers from University of California- Davis and Yale University investigated the endocrine disrupting properties of triclocarban and other polychlorinated diphenyl urea compounds by exposing human cells and rats to levels similar to those found in people. Triclocarban was found to have a synergistic interaction with the sex hormone, testosterone- present in both males and females. This interaction produced a positive, amplified biological effect, which is likely to hyperstimulate native sex hormones. This amplification of sex hormone activity occurs at the target cell and can result in developmental defects or decreased reproductive function. Researchers further explained that ovulation and ovarian function in females can be disrupted, while sperm quality can be decreased in males. The researchers also point out that the results of their study create a new category for endocrine disruptive substances […]

(Beyond Pesticides, October 29, 2007) European Parliament members voted in favor of tighter pesticide legislation Tuesday, passing the first hurdle to enacting laws that would protect the EU’s most vulnerable communities, ensure high quality food, and prevent residues from accumulating in the environment. The European Commission’s proposal places a general ban on aerial spraying, heavily restricts the usage of pesticides in public areas, and plans to cut the use of “active substances of very high concern” by at least half by 2013. A majority of EU Member States need to approve the changes before the package can come into effect, and government representatives will meet on November 26 to debate the proposals.“This is something consumers want. They don’t want poison on their plates, they don’t want poison in their environment,” said German Green Party MEP Hiltrud Breyer. By targeting the most toxic chemicals and the areas that face the highest risk from pesticide exposure, the proposed measures would cut total usage by 5 or 6 percent in the EU, where 300,000 tons of pesticides are sold each year. The EU produces one quarter of the world’s supply of pesticides, 230,000 tons each year, despite it only accounting for 4 per […]

(Beyond Pesticides, September 24, 2007) Seven representatives wrote to the EPA last Thursday, urging the government agency to act promptly to identify and screen products for dangerous endocrine-disrupting chemicals. The letter asks EPA Administrator Stephen Johnson to provide definite deadlines in the testing and control of endocrine disruptors, which are substances that interfere with the normal functioning of the endocrine system, responsible for hormonal and developmental processes. EPA’s regulation of these substances that mimic or alter natural hormonal processes has been slow and lacks direction to meet set goals promptly, according to the U.S. Representatives. “To date, EPA’s efforts in this area have been characterized by missed deadlines, prolonged delays, and inadequate incorporation of public input,” according to the letter from the House Committee on Oversight and Government Reform, chaired by Rep. Henry Waxman (D-California). Ranking Minority Member on the Committee Tom Davis (R-Virginia); Representatives Elijah Cummings (D-Maryland), Chris Van Hollen (D-Maryland), Wayne Gilchrest (R-Maryland), and Jim Moran (D-Virginia); and Delegate Eleanor Holmes Norton (D-D.C.) also signed the letter to EPA. Advocates say that EPA’s lack of urgency on endocrine disruptors leaves the American population and future generations at risk for adverse health effects from exposure to these substances through […]

(Beyond Pesticides, June 29, 2007) On June 28, 2007, forty years after it received protection under the Endangered Species Act (ESA) and thirty-five years after the banning of DDT in the U.S., the bald eagle was removed from the ESA’s “threatened” list. Bald eagle populations declined dramatically in the last century, attributed mostly to the accumulation of the pesticide DDT in fish, a staple of the eagle’s diet. The pesticide gradually poisoned females, causing them to produce thinly-shelled eggs that broke easily, preventing the embryos from growing. Years of hunting, accidental poisoning and habitat loss took an additional toll. “The rescue of the bald eagle from the brink of extinction ranks among the greatest victories of American conservation.” said John Flicker, President of the National Audubon Society. “Like no other species, the bald eagle showed us all that environmental stewardship has priceless rewards. In every state, parents and grandparents can still point to the sky and share a moment of wonder as a bald eagle soars overhead.” The U.S. Fish and Wildlife Service (FWS) in 1967 listed the bald eagle as endangered, a designation that gave the bird legal protection from harmful human activities and in 1972, the U.S. Environmental […]