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Ten Years Later, EPA to Begin Screening Endocrine Disrupting Pesticides

Tuesday, June 12th, 2007

(Beyond Pesticides, June 12, 2007) More than 10 years after being directed to do so by Congress, the Environmental Protection Agency (EPA) has announced that it will test 73 pesticides for their potential to damage the endocrine system and disrupt the normal functioning of hormones in the body, the agency announced in a press release yesterday. EPA is seeking comments on the draft list of 73 pesticides to be evaluated under the new screening regimen. The 1996 Food Quality Protection Act (FQPA) set a 1999 deadline for EPA to develop a battery of assays with which pesticide manufacturers will be required to screen their products as possible endocrine (hormonal) disrupters, similar to tests required to determine whether chemicals cause cancer, birth defects, genetic mutations, or other problems. EPA has repeatedly pushed back the deadline and despite claims to be “a leader in endocrine disruptor research,” EPA has yet to test a single chemical under the protocol. EPA draft list of 73 pesticide ingredients, including both active and inert ingredients, were chosen based on their relatively high potential for human exposure. According to the press release, priority was given “to pesticide active ingredients where there is the potential for human exposure […]

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More Evidence Links Endocrine Disruptors to Frog Sex Changes

Friday, March 9th, 2007

(Beyond Pesticides, March 9, 2007) New research shows that frogs are more sensitive to hormone-disturbing environmental pollutants than was previously thought. Male tadpoles that swim in water with environmentally relevant levels of such substances become females, according to the study that will be published in the scientific journal Environmental Toxicology and Chemistry (ET&C) in May (See University Press Release). The results may shed light on at least one reason that up to a third of frog species around the world are threatened with extinction, suggests the study. In a laboratory experiment by researchers in Sweden, two species of frogs, the European common frog (Rana temporaria) and the African clawed frog (Xenopus tropicalis), were exposed to levels of oestrogen (estrogen or chemicals mimicking the effect of estrogen) similar to those detected in natural bodies of water in Europe, the United States and Canada.The results were startling: whereas the percentage of females in two control groups was under 50 percent – not unusual among frogs – the sex ratio in the groups of tadpoles who matured in water dosed with different levels of oestrogen were significantly skewed. Even tadpoles exposed to the weakest concentration of the hormone were, in one of the […]

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Fetal Exposure to Common Chemicals Can Activate Obesity

Wednesday, February 21st, 2007

(Beyond Pesticides, Feb 21, 2007) Exposure to environmental chemicals found in everyday plastics and pesticides while in the womb may make a person more prone to obesity later in life, new research indicates. Frederick vom Saal, Ph.D, professor of biological sciences at University of Missouri-Columbia’s College of Arts and Science, has found that when fetuses are exposed to endocrine-disrupting chemicals, the way their genes function may be altered to make them more prone to obesity and disease. Dr. vom Saal presented his research last week at the annual meeting of the American Association for the Advancement of Science (AAAS) in San Francisco. “Perinatal Programming of Obesity: Interaction of Nutrition and Environmental Exposures” is the title of Dr. vom Saal’s AAAS presentation. “Certain environmental substances called endocrine-disrupting chemicals can change the functioning of a fetus’s genes, altering a baby’s metabolic system and predisposing him or her to obesity,” said Dr. vom Saal. “This individual could eat the same thing and exercise the same amount as someone with a normal metabolic system, but he or she would become obese, while the other person remained thin,” he said. Obesity puts people at risk for other problems, including cancer, diabetes, cardiovascular disease and hypertension. […]

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