(Beyond Pesticides, June 6, 2008) A recent study by the National Institutes of Health (NIH), including the National Institute of Environmental Health Sciences (NIEHS) and the National Cancer Institute (NCI), finds pesticide applicators with regular exposure to pesticides to be at a greater risk of type-2 diabetes. Published in the American Journal of Epidemiology (DOI: 10.1093/aje/kwn028), the study shows specific pesticides produce between a 20 and 200 percent increase in risk. Researchers looked at data from 31,787 pesticide applicators in North Carolina and Iowa over a period of five years. In that period, 1,171, or 3.7 percent, had developed diabetes, particularly for applicators in the highest category of lifetime days of use of any pesticide. “The results suggest that pesticides may be a contributing factor for diabetes along with known risk factors such as diabetes, lack of exercise and having a family history of diabetes,” said Dale Sandler, PhD, chief of the Epidemiology Branch of NIEHS. “Although the amount of diabetes explained by pesticides is small, these new findings may extend beyond the pesticide applicators in the study.” Freya Kamel, PhD, of NIEHS noted that “all of the seven pesticides” associated with an increased risk of type 2 diabetes are […]

(Beyond Pesticides, May 30, 2008) A recent study has linked the common herbicide atrazine with endocrine disruption in both fish and human cells. Entitled “The Herbicide Atrazine Activates Endocrine Gene Networks via Non-Steroidal NR5A Nuclear Receptors in Fish and Mammalian Cells,” the University of Califonia, San Francisco (UCSF) research examines the reaction of zebrafish to environmentally relevant levels of atrazine, and mirrors the study in human placental cells. The zebrafish, which are particularly sensitive to endocrine disruptors,  are “feminized”  in greater proportion than the unexposed control group. Fish exposed to atrazine for 48 hours at levels found in agricultural runoff produced twice as many female fish as male. “These fish are very sensitive to endocrine disrupting chemicals, so one might think of them as ‘sentinels’ to potential developmental dangers in humans,” said senior author Holly Ingraham, PhD. “These atrazine-sensitive genes are central to normal reproduction and are found in steroid producing tissues. You have to wonder about the long-term effects of exposing the rapidly developing fetus to atrazine or other endocrine disruptors.” In human cell studies, the researchers found that atrazine activates genes involved in hormone signally and steroid synthesis. “Endocrine-related cell types with a capacity for steroid generation appear […]

(Beyond Pesticides, May 29, 2008) A study published in the May issue of Environmental Health Perspectives shows a link between prenatal exposure to the pesticide DDT and poor attention-related skills in early infancy. This study follows in a long line of recent studies associated with the negative health effects of DDT including: diabetes; non-Hodgkin lymphoma; breast cancer; and autism. Despite the fact that DDT was banned in the U.S. in 1972, concentrations of this toxic chemical’s major metabolite, DDE, have remained alarmingly high in many ecosystems, including the waters of Los Angeles County, the arctic, and even U.S. national parks. All studies documenting the health effects of DDT and chemicals in the same family, organochlorines, are particularly important not just for understanding the lingering effects of DDT from days past, but because many countries continue to employ DDT as a method in controlling mosquitoes that transmit malaria, despite its toxicity, weakening efficacy, and availability of safer alternatives. Other organochlorines are still registered for use in the U.S.The study looked at 788 mother-infant pairs who met several criteria, which included living in a town adjacent to a Superfund site in New Bedford, Massachusetts, a location with known organochlorine contamination. Cord blood […]

(Beyond Pesticides, May 28, 2008) Researchers have begun preliminary work to find suitable and safe alternatives to the widely used mosquito repellent DEET. Several possibilities have been identified, which repel mosquitoes for longer periods of time, but their safety for use on humans still needs to be investigated.Researchers, with funding from the Department of Defense, set out to determine what makes insect repellents work, and then to use that information in finding more effective ways to chase away disease-carrying insects. Insect repellents are used to repel biting insects such as mosquitoes and ticks that spread diseases such as encephalitis, Lyme disease, Rocky Mountain spotted fever, malaria and dengue fever. Ulrich R. Bernier, PhD, co-author of this study published online in the Proceedings of the National Academy of Sciences http://www.pnas.org/ and research chemist at the Agriculture Department’s mosquito and fly research unit in Gainesville, Fla., remarked that several of the new chemicals reviewed were “just phenomenal.” Using previous USDA data on hundreds of chemicals collected over 50 years, the researchers rated chemicals from “1” to “5” on ability to repel insects, and then focused on what the most effective ones ”” the 5s ”” had in common. They were able to […]

(Beyond Pesticides, May 27, 2008) A population-based study looking at how genes and environmental factors interact shows that pet shampoos containing insecticides may trigger autism spectrum disorders (ASD), reports New Scientist. The study findings, presented at the International Meeting for Autism Research, show that mothers of children with an ASD are twice as likely to have used an insecticidal pet shampoo during the prenatal and/or postnatal period when compared to mothers of healthy children. The strongest association was during the second trimester of pregnancy. According to the researchers, pet shampoos often contain pyrethrins and previous animal research has found that pyrethrins are designed to target the central nervous system in insects, rodents and other species and can cause death of neurons and compromise the blood-brain barrier in early life.Examining participants in the Childhood Autism Risks from Genetics and the Environment (CHARGE) study, researchers from the University of California, Davis looked at 333 children with ASD and 198 healthy children between the ages of two and five, and their families. In-depth questionnaires and blood and urine samples were collected. Isaac Pessah, Ph.D., a researcher involved in the study and professor in the Department of Molecular Biosciences, College of Veterinary Medicine at […]

(Beyond Pesticides, May 23, 2008) In the midst of dramatically declining bee populations, the German Office for Consumer Protection and Food Safety (BVD) has suspended the approval of eight toxic insecticides believed to be responsible for the fate of these important pollinators. The suspended products include pesticides containing imidacloprid and clothianidin, the majority of which are produced by Bayer Company and have been suspected for years of contributing to declining bee populations.France banned the use of imidacloprid on corn and sunflowers in 1999, and rejected Bayer’s application for clothianidin this year. Despite the call for prohibition of imidacloprid from German apiarists and environmental groups as early as 2004, a crisis in bee populations–a reported 50-60% loss, finally forced the government to take action. The U.S., where these products are still approved for use, has also been experiencing extremely alarming rates of bee colony collapse, while areas away from cropland have thriving bee populations. Imidacloprid and clothianidin are both neonicotinoids, meaning that they target nerve cells in a similar way to nicotine, acting as neurotoxins to sucking insects such as beetles and aphids. Clothianidin was approved for use in the U.S. in 2003 as a seed treatment for corn and canola, […]

(Beyond Pesticides, May 20, 2008) On May 19, 2008, scientists, Arctic tribal governments and Indigenous groups and environmental health advocates sent letters calling on the Environmental Protection Agency (EPA) to phase out the organochlorine pesticide endosulfan.“It is time to take this dangerous and antiquated pesticide off the market,” says Jennifer Sass, Ph.D., a senior scientist with the Natural Resources Defense Council. “The scientific evidence clearly shows that the continued use of this chemical puts the health of exposed farmworkers, communities and the environment at risk.” Dr. Sass is one of over 55 international scientists, medical doctors, nurses, and other health professionals urging EPA to take action on endosulfan in a letter to Administrator Stephen Johnson. Prominent scientists endorsing the letter include Philip Landrigan, M.D., M.Sc., a pediatrician and Director of the Center for Children’s Health and the Environment at the Mount Sinai School of Medicine and Ronald Herberman, M.D. and Devra Davis, Ph.D., M.P.H., researchers at the University of Pittsburgh Cancer Institute. Used in the U.S. on tomatoes, cotton and other crops, endosulfan harms the hormone system, and low levels of exposure in the womb have been linked to male reproductive harm, other birth defects and possibly autism. Acute poisoning […]

(Beyond Pesticides, May 19, 2008) A 20-year study by the National Oceanic and Atmospheric Administration (NOAA) shows that environmental laws enacted in the 1970s are having a positive effect on reducing overall contaminant levels in coastal waters of the U.S. However, the report points to continuing concerns with elevated levels of metals and organic contaminants found near urban and industrial areas of the coasts. The report, “NOAA National Status and Trends Mussel Watch Program: An Assessment of Two Decades of Contaminant Monitoring in the Nation’s Coastal Zone from 1986-2005,” findings are the result of monitoring efforts that analyze 140 different chemicals in U.S. coastal and estuarine areas, including the Great Lakes.“It’s interesting to note that pesticides, such as DDT, and industrial chemicals, such as PCBs, show significant decreasing trends around the nation, but similar trends were not found for trace metals,” said Gunnar Lauenstein, manager of the NOAA Mussel Watch program. “What is of concern is that there are contaminants that continue to be problematic, including oil-related compounds from motor vehicles and shipping activities.” Significant findings from this report include the following: Decreasing trends nationally of the pesticide DDT are documented with a majority of the sites monitored along the […]

(Beyond Pesticides, May 16, 2008) Pressured by environmental organizations to protect children’s health and water quality in the Great Lakes, the Michigan House of Representatives has approved restrictions on the use of lindane, a toxic organochlorine pesticide used as a prescription drug to treat lice and scabies.  Under the legislation (HB 4569), the use of lindane  would be  prohibited except “under the supervision of a physician in his or her office if the physician considers the use of that product necessary for the treatment of a patient’s lice or scabies.” The Michigan Senate has not yet voted on the bill. Lindane has long been known for its neurotoxic properties, causing seizures, damage to the nervous system, and weakening of the immune system. It is also a probable carcinogen and endocrine disruptor. When used on people, lindane is regulated by the Food and Drug Administration (FDA). Despite the fact that it has been banned in 52 countries and restricted in over 30 more, FDA continues to allow its use in the U.S., albeit with a Public Health Advisory issued in 2003 that states, “Lindane should be used with caution in infants, children, the elderly, patients with skin conditions, and patients with […]

(Beyond Pesticides, May 8, 2008) New research shows that melting Antarctic glaciers are releasing once frozen stores of persistent organic chemicals, now banned in many parts of the world. Marine biologist, Heidi Geisz, a Ph.D. student at the Virginia Institute of Marine Science studying the fate and effect of organic contaminants in the Antarctic, has found that DDT concentrations in penguins has remained at the same levels as they were 30 years ago, when DDT was widely used. Arctic animals such as whales, seals and birds have had a significant decline in their DDT levels during the past decades, while the more stationary Antarctic penguins have not. The study, “Melting Glaciers: A Probable Source of DDT to the Antarctic Marine Ecosystem,” published in Environmental Science and Technology (DOI: 10.1021/es702919n), identifies the melting snow and ice as the continued source of total DDT in this southern ecosystem. The release of DDT also means that other persistent organic pollutants (POPs), including PCBs and PBDEs — industrial chemicals that have been linked to health problems in humans, are also being released. “DDT is not the only chemical that these birds are ingesting and it is certainly not the worst,” Ms. Geisz says. Ms. […]

(Beyond Pesticides, May 6, 2008) Pregnant veterinarians who have occupational exposures to pesticides, anesthetic gases or radiation may have twice the risk of miscarriage, according to a new study published in the May 2008 issue of the journal Occupational and Environmental Medicine. The study, “Maternal occupational exposures and risk of spontaneous abortion in veterinary practice,” looked at the experiences of 1197 female veterinarians working in clinical practice, who graduated from Australian veterinary schools between 1960 and 2000, responding to a questionnaire-based survey. There was a twofold increase in the risk of miscarriage in women veterinarians who use pesticides at work. The researchers found that there was also a twofold increase for those exposed to anaesthetic gases for more than an hour a week without using equipment to remove the gas from the air, and an 80 percent greater risk of miscarriage in those who performed more than five x-ray examinations per week compared with those who performed five or less. Veterinarians are often unable to leave the room whilst performing an x-ray because they have to hold the animal being x-rayed in order to restrain it. Adeleh Shirangi, Ph.D., author of the research from the Department of Epidemiology and Public […]

(Beyond Pesticides, April 29, 2008) In the wake of provincial laws banning lawn chemicals, the Canadian division of Home Depot announced on April 22, 2008 that it will stop selling traditional pesticides in its stores across Canada by the end of 2008 and will increase its selection of environmentally friendly alternatives. Home Depot Canada is the first major home improvement retailer to stop selling pesticides nationwide.The decision coincides with legislation introduced on April 23, which bans the sale and cosmetic use of pesticides on lawns, gardens and parks in the Canadian province of Ontario. Quebec passed a similar ban in 2003. Additionally, there are currently over 55 municipalities in Canada where the residential use, but not sale, of pesticides is banned. Other garden supply and grocery stores have also stopped selling pesticides in Ontario and Quebec, but the Home Depot decision will affect stores nationwide. Environmental and public health activists believe the provincial bans and Home Depot phase-outs demonstrate that the country has reached a tipping point. “I would say that now that we have Quebec and Ontario, there is huge pressure on the other provinces. The next obvious one would be British Columbia.” Gideon Forman, executive director of the […]

(Beyond Pesticides, April 23, 2008) Ontario is moving to reduce exposure to toxic chemicals by banning the sale and cosmetic use of pesticides. Legislation to be introduced today would make Ontario’s pesticide rules among the toughest in North America. It would also replace a variety of municipal by-laws in place across the province.Studies by public health experts are showing growing evidence of the potential health risk of pesticides, particularly for children. The ban would likely take effect next spring. It would not affect pesticides used for farming or forestry. Golf courses would still be able to use pesticides, but must meet certain conditions to minimize environmental impacts. Pesticides would still be allowed for control of mosquitoes and other insects determined to represent a health threat. “Our generation is becoming more and more aware of the potential risks in our environment, not only to our health, but to our children’s health. That’s why we’re taking action on behalf of the next generation of Ontarians, and reducing their exposure to chemicals,” said Premier Dalton McGuinty. “Many municipalities have already shown leadership in banning or restricting cosmetic-use pesticides. We’re extending that protection to all families wherever they live,” said Environment Minister John Gerretsen. […]

(Beyond Pesticides, April 22, 2008) Earth Day, traditionally celebrated by the United Nations on the spring equinox, became a U.S. national holiday proclaimed by Senators Gaylord Nelson and John McConnell on April 22, 1970. It is a time to celebrate our planet, and all the life giving natural resources and beauty that the Earth provides and which we too often take for granted. Most memorable holiday traditions involve family, friends, and of course, food. Building on this idea, the folks at the Organic Valley Family of Farms Cooperative joined with environmental and sustainable agriculture organizations to develop the Earth Dinner celebration. In developing the Earth Dinner idea, the organizers wondered, “Why doesn’t Earth Day have a tradition?” The Earth deserves a celebration too, and it made sense that an Earth Day tradition should revolve around local, sustainable and organic cuisine, and especially meaningful discussion about the impact farming has on the environment. Buying foods grown and distributed locally supports the local farmers, allowing them and their families to stay on the land. Buying foods that were grown using sustainable agricultural practices protects the soil and environment in countless ways. Going organic ensures that you are feeding your loved ones foods […]

(Beyond Pesticides, April 15, 2008) Thanks to the organizing efforts of the local Environmental Action Task Force, the town of Greenwich, CT has banned the use of pesticides on all of its athletic fields. The first application of the year, which was set for April 14, 2008, was cancelled after the Board of Selectmen passed a resolution mandating the ban. “It’s very exciting,” Selectman Lin Lavery told Greenwich Time newspaper. “It shows the town’s commitment to being a leader on environmental issues.” According to the newspaper, the Environmental Action Task Force proposed the resolution in response to a state law banning the use of pesticides on all elementary and middle school grounds, that goes into effect next year. But the task force took the mandate a step further, banning pesticides on all town athletic fields and instituting it a year early. It seemed logical to move forward with a ban as quickly as possible once it was determined that these pesticides were toxic and potentially harmful to children, Lavery told Greenwich Time. Pesticides, such as Barricade- containing the active ingredient prodiamine, which is used on town fields, is a possible human carcinogen and suspected endocrine disruptor. Michael Franco, M.D., a […]

(Beyond Pesticides, April 11, 2008) The United States House of Representatives’ Committee on Oversight and Government Reform released a report last month on the Food and Drug Administration (FDA) failures that lead to the E.coli outbreak in spinach, which peaked in September 2006. When E.coli was discovered in package spinach, critics of organic agriculture and parts of the media were quick to target organic spinach as the source (starting something of a debunking “war”). NBC’s Today Show erroneously blamed organic agriculture (to which Beyond Pesticides responded here). However, the Congressional report lists a variety of failures on the part of FDA to ensure safe handling and packaging of spinach, citing a limited number of inspections and failure to enforce adequate sanitation and processing practices. The major faults found by the committee range from frequency and thorughness of inspections, to lack of enforcement, including: Packaged fresh spinach facilities were inspected only once every 2.4 years, less than half of FDA’s stated goals. FDA observed objectionable conditions during 47% of the packaged fresh spinach inspections [60% of which pertained to facility sanitation]. Despite observing objectionable conditions in packaged fresh spinach facilities, FDA took no meaningful enforcement action. FDA overlooked repeated violations. FDA […]

(Beyond Pesticides, April 10, 2008) Common frogs that live in suburban areas are more likely than their rural counterparts to develop reproductive abnormalities, according to David Skelly, PhD, professor of ecology at the Yale School of Forestry and Environmental Studies. This phenomenon becomes a serious concern as the frog’s mating season begins, leaving researchers to wonder: will frogs be clear on their role in the annual ritual? Research by Dr. Skelly, soon to be published, focuses on the common green frog, Rana clamitans, within the Connecticut River Valley. A total of 233 frogs were collected from various ponds and landscapes with the river valley and among them 13 percent have abnormalities occurring in their reproductive organs. In urban areas, 18 percent of the collected frogs are intersex, and in suburban areas 21 percent. Frogs collected from agricultural areas have the lowest rate of reproductive problems with just 7 percent classified as intersex. According to Dr. Skelly, the more suburban the land cover, the more likely the abnormalities. “This is the first evidence that I think anyone has provided that agriculture is doing anything but pushing those rates higher,” remarked Dr. Skelly of the intersex phenomena. In an attempt to explain […]

(Beyond Pesticides, April 8, 2008) A team of University of Michigan scientists discover interactions between genes and organophosphate exposure cause some forms of motor neuron disease (MND). The study, which appears in the March issue of the American Journal of Human Genetics, shows the mutations in one key gene (neuropathy target esterase, or NTE) that causes a previously unknown type of inherited MND. The scientists also find the mutations caused changes in a protein already known to be involved when people develop neurologic disorders as a result of exposure to toxic organophosphate chemicals commonly used in solvents and insecticides and also as “nerve gas” agents. Motor neuron disease is a rare, devastating illness in which nerve cells that carry brain signals to muscles gradually deteriorate. One form of it is Lou Gehrig’s disease or ALS (amyotrophic lateral sclerosis). For most MND patients, the cause is unknown. Figuring out why these people develop the disease, which causes muscles to weaken, atrophy and cease to function, is an important step in developing therapies to treat or prevent motor neuron disease. Motor neuron disease affects five per 100,000 people. “Our findings support the possibility that toxic organophosphates contribute to motor neuron disease in […]

(Beyond Pesticides, April 7, 2008) A coalition of farmworker advocates and environmental groups filed a lawsuit against the Environmental Protection Agency (EPA) to stop the continued use of four deadly organophosphate pesticides. These pesticides were derived from nerve gas developed during World War II. Some of these pesticides have been detected in California’s rural schoolyards and homes, Sequoia National Park, and Monterey Bay. The four organophosphates at issue in the case filed April 4 are methidathion, oxydemeton-methyl, methamidophos, and ethoprop. They are used primarily in California on a wide variety of fruit, vegetable, and nut crops. “These four pesticides put thousands of farmworkers and their families at risk of serious illness every year,” said Patti Goldman, an attorney for Earthjustice, the environmental law firm that represents the coalition. “It is inexcusable for EPA to allow use of pesticides that they know are harming people, especially children.” EPA has documented that children are especially susceptible to poisoning from organophosphates. Exposure can cause dizziness, vomiting, convulsions, numbness in the limbs, loss of intellectual functioning, and death. Some organophosphates also cause hormone disruption, birth defects, and cancer. “Farmworkers, and all people living in and near agricultural regions, especially children, are at great risk […]

(Beyond Pesticides, April 4, 2008) A study called “Long-term persistence of GM oilseed rape in the seedbank,” recently published in the journal Biology Letters, has found a genetically modified (GM) crop to persist in spite of a decade of efforts to remove it from a field. Researchers from Sweden’s Lund University and the Danish Technical University found GM oilseed rape (also known as canola) plants still growing ten years after seeds were planted. According to the study, the result contrasts previous trials: “In general, studies suggest that the majority of seeds disappear from the seedbank within two years.” The oilseed rape volunteer (rogue) plants were discovered by their resistance to the herbicide glufosinate. Researchers wrote, “This finding of volunteers, despite labour intensive control for 10 years [including intensive chemical spraying], supports previous suggestions that voulnteer oilseed rape needs to be carefully managed in order for non-GM crops to be planted after GM crops.” They added, “These results are important in relation to debating and regulating coexistence of GM and non-GM crops.” The study’s findings are consistent with previous research. A larger French study found similar survival of volunteer plants eight years after a GM trial. Swedish researcher Dr. Tina D’Hertefeldt […]

(Beyond Pesticides, April 3, 2008) Wines on sale in the European Union (EU), including wines made by world famous vineyards, contain residues of a number of pesticides, according to a new report by Pesticide Action Network Europe. The organization tested 40 bottles of wine purchased inside the EU from Australia, Austria, Chile, France, Italy, Germany, Portugal and South Africa, six of which were organic wines. Every bottle of conventional wine included in the analysis was found to contain pesticides, with one bottle containing 10 different pesticides. On average each wine sample contained over four pesticides. The analysis revealed 24 different pesticide contaminants, including five classified as being carcinogenic, mutagenic, toxic to the reproductive system or endocrine disrupting. The most widespread pesticide contaminant was pyrimethanil, a possible carcinogen, which was detected in 25 bottles of conventional wine — almost 75% of all conventional samples analyzed. While the majority of wines tested were selected from low cost affordable brands, three of the bottles are world famous Bordeaux wines and more expensive, according to PAN Europe. The discovery of pesticides in samples of wine follows the publication of a report by the French Ministry of Agriculture which identified 15 pesticides as being systematically […]

(Beyond Pesticides, April 2, 2008) A study that analyzed chemical contamination in clothes found that fabrics absorb high concentrations of moth repellents, and retain these concentrations even after prolonged airing. These contaminated fabrics then serve as secondary sources of indoor air pollution once the chemicals are released back into the air. Moth repellents, which contain naphthalene and/or p-dichlorobenzene, as well as camphor, have been recognized as major contributors to indoor air pollution. However, their persistence in the fabrics they are used to protect has been underestimated. The study entitled, “Domestic sampling: Exposure assessment to moth repellent products using ultrasonic extraction and capillary GC-MS,” published in Chemosphere, revealed that once cloths are exposed to moth repellents, whether directly or indirectly, high concentrations of p-dichlorobenzene, naphthalene and camphor are detected even after airing. A regular cotton shirt, for example, placed in a cabinet containing one tablet of moth repellent was found to contain up to 7, 3 and 7.5mg of p-dichlorobenzene, naphthalene and camphor respectively after airing for 1 hour. These concentrations are high when compared with the average exposure to p-dichlorobenzene at about 35 micrograms (μg), and the average indoor exposure from naphthalene at less than 1ppb. While airing did reduce […]

(Beyond Pesticides, April 1, 2008) On March 27, many distinguished environmental health and justice advocates in addition to political leaders gathered in Los Angeles, CA to express their gratitude & praised the efforts of the Los Angeles Unified School District, (2nd largest in the nation) for working cooperatively for a decade with California Safe Schools (CSS), a children’s environmental health organization in creating the most protective pesticide policy for schools in the country. California Safe Schools (CSS) was formed by Robina Suwol in 1998, following an incident with her then 6-year-old son Nicholas, a student at Sherman Oaks Elementary School. Unaware students were present, a school gardener in a hazardous materials suit sprayed the herbicide Princep, creating a cloud of pesticide mist students were forced to walk through in order to reach their classrooms. Later, Nicholas, whose asthma had previously been under control, experienced a life-threatening asthma attack. Ms. Suwol’s initial research on a web site sponsored by Cornell University revealed that a single exposure to Princep could be very dangerous to children, and may cause tremors, convulsions & paralysis, among other symptoms. Further investigation revealed that many chemical pesticides commonly used in schools carry significant risks to growing children […]