(Beyond Pesticides, January 18, 2024) Research continues to raise alarms about the hazards associated with the use of plastic, including the microplastic particles that are distributed in alarming amounts throughout the environment and taken up by organisms, including humans. A study published by researchers at Columbia and Rutgers universities (see article in the Proceedings of the National Academy of Sciences, January 2024) reports that the average liter of three brands of bottled water in the U.S. contains almost a quarter of a million tiny plastic pieces, of which 90 percent are at the nanoscale. The other ten percent are slightly larger, at microscale. Last December, researchers at Norway’s MicroLEACH project published a study that analyzes the components of 50 items in common use—plastic bags, disposable cups, dishwashing gloves, car tire granules, children’s toys and balloons. (See summary.) The researchers found, like in previous studies, that many hazardous chemicals in the plastics as well as many that could not be identified because they were not listed in the major chemical substance databases. Only 30 percent of the chemical compounds identified in the study were present in two or more products. This suggests that most plastics contain many unidentified chemicals, far beyond […]

(Beyond Pesticides, January 16, 2024) The U.S. Environmental Protection Agency (EPA) has long been criticized for its failure to evaluate the effectiveness (or efficacy) of all the pesticides it registers. A petition, for which there is now an open public comment period (submit comments by January 22, 2024), challenges what advocates call a basic failure of the agency to evaluate the claimed benefits of pesticides. Because of this long-standing situation, those who purchase pesticides do not know that the pesticides they buy will meet expectations for control. For farmers, that means that EPA has not evaluated whether the pesticide’s use actually increases productivity of the treated crops and/or whether over time the target pest (weed, insect, fungus) will become resistant. For consumers, it also means that there is not an independent analysis of whether the pesticide products work. As EPA implements the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), not only is there no agency assessment of whether the pesticide’s use will achieve its intended purpose, there is not a determination as to whether there is a less toxic way of achieving the pest management goal. As Beyond Pesticides cited last year, a piece published in the Proceedings of the […]

(Beyond Pesticides, January 12, 2024) As we commemorate Dr. Martin Luther King Jr.—an inspiration for taking on the challenges of justice, equity, and safety as a central part of all our work for a sustainable future—through a day that stands for equality, justice, and the pursuit of a better world, it is crucial to reflect on issues that impact the health and well-being of communities. One such issue that echoes the spirit of Dr. King’s vision is the pervasive use of pesticides and the associated health risks. Drawing insights from prior articles on Beyond Pesticides’ Daily News, we delve into the intersection of environmental justice, public health, and the ongoing struggle for a safer and healthier world.  The Invisible Threat with Visible Consequence: Pesticides and Health.  Beyond Pesticides sheds light on the hidden dangers of pesticide exposure and the disproportionate impact it has on marginalized communities. Communities of color and economically disadvantaged areas bear a heavier burden of pesticide exposure, leading to higher rates of health issues, including respiratory problems, developmental disorders, and certain cancers.  From agricultural workers to residents of low-income neighborhoods, the adverse health effects of pesticides are not evenly distributed. The use of pesticides without adequate consideration […]

(Beyond Pesticides, January 9, 2024) A “landscape-level” study finds that typical risk assessment studies used by the U.S. Environmental Protection Agency (EPA) and European regulators fail to “safeguard bees and other pollinators that support agricultural production and wild plant pollination.” The study, published in Nature (November 2023), evaluates the health of bumble bees (Bombus terrestris) as a sentinel species placed in 106 agricultural landscapes across Europe. The authors’ conclusions challenge “the current assumption of pesticide regulation—that chemicals that individually pass laboratory tests and semifield trials are considered environmentally benign”—calling into question EPA’s persistent failure to adequately regulate mixtures of chemicals to which organisms are exposed in the real world. This study adds to the body of science on pesticide mixtures adversely affecting bee and pollinator health. See here, here, and here. The failure to capture real-world exposure to pesticide mixtures in its regulatory assessments extends to EPA’s systemic failure to evaluate a range of serious adverse impacts, as noted by the agency’s Office of Inspector General (OIG) report. And, aquatic environments also have documented mixtures of pesticides, with the U.S. Geological Survey finding 90 percent of water samples containing at least five or more different pesticides. “We can take no comfort […]

(Beyond Pesticides, January 3, 2024) A study published in Environmental Health Perspectives finds elevated, chronic exposure to glyphosate throughout one’s lifetime increases the risk of mosaic loss of chromosome Y (loss of chromosome Y occurs to many men in some cells due to aging [mLOY]) that impacts a noticeable fraction of cells. Although the loss of this sex chromosome does not cause cell death, like the loss of autosomal chromosomes, the risk of mLOY is a biomarker for genotoxicity (the damage of genetic information within a cell causing mutations from chemical exposure, which may lead to cancer) and expansion of cellular response to glyphosate, resulting in the precursor for hematological (blood) cancers. This study is one of the first to identify sex-specific chromosome degradation, with stark evidence demonstrating links to various cancers, including non-Hodgkin lymphoma. The International Agency for Research on Cancer (IARC) has classified the glyphosate as a probable carcinogen or cancer-causing chemical. However, the U.S. Environmental Protection Agency’s (EPA) allowance of widespread use of glyphosate allows for adverse impacts, especially among vulnerable individuals, like pregnant women, infants, children, and the elderly. Glyphosate exposure levels and resulting residues in urine has been documented with recent data showing that four out of five (81.6%) […]

(Beyond Pesticides, December 20, 2023) A federal district court decision last week (December 13) found illegal the U.S. Environmental Protection Agency’s (EPA) decision to register the antibiotic streptomycin for use in Florida citrus to control Huanglongbing (HLB), also known as “citrus greening,” a plant disease spread by the Asian citrus psyllid. This decision comes just as EPA may allow yet another controversial pesticide, aldicarb, whose registration faces similar issues of agency malfeasance. The streptomycin lawsuit, filed in 2021 by a coalition of farmworker and public interest groups including Beyond Pesticides, raises critical issues of antibiotic resistance, public health protection, and impacts on bees. The case was filed by: Natural Resources Defense Council and U.S. PIRG, represented by NRDC; Beyond Pesticides, Environmental Confederation of Southwest Florida (ECOSWF), Farmworker Association of Florida, Farmworker Justice, and Migrant Clinicians Network, represented by Earthjustice; and the Center for Biological Diversity, represented by in-house counsel. The Ninth Circuit Court of Appeals took EPA to task for its failure to conduct required analyses and issue findings to support the use of streptomycin for citrus greening. The court is particularly concerned about the agency’s failure to reach findings on the impacts on bees and the agency’s responsibility for […]

(Beyond Pesticides, December 19, 2023) Last week, farmworker organizations and Beyond Pesticides, represented by the Center for Food Safety, filed a petition with the U.S. Environmental Protection Agency (EPA) urging that the weed killer glyphosate be removed from the market. The petition cites 200 studies, which represent a fraction of the independent scientific literature on the hazards of glyphosate and formulation ingredients of glyphosate products. This action follows previous litigation in 2022 in which a federal court of appeals struck down EPA’s human health assessment, finding that the agency wrongfully dismissed glyphosate’s cancer risk. The farmworker groups petitioning include Farmworker Association of Florida, Organización en California de Lideres Campesinas, Alianza Nacional de Campesinas, and the Rural Coalition.   Meanwhile, verdicts against glyphosate’s manufacturer, Bayer, continue to pile up with a December jury verdict in Pennsylvania awarding $3.5 million and a November jury in Missouri ordering $1.56 billion to be paid to four plaintiffs. All link their cancer to use of the Roundup. Bayer has lost almost all of the cases filed against it for compensation and punitive damages associated with plaintiffs’ charge that its product (previously manufactured by Monsanto) caused them harm.  The petition summarizes its purpose and justification as […]

(Beyond Pesticides, December 15, 2023) Drawing on a recent gathering of international scientists, a group of 34 scientists published a call for much stricter scrutiny of researchers’ conflicts of interest by agencies that regulate and register chemicals, with recommendations for the newly formed Intergovernmental Science Policy Panel. Writing in Environmental Science & Technology, the authors, led by Andreas Schäffer of Aachen University in Germany and Martin Scheringer of Masaryk University in the Czech Republic, cite an abundance of examples of chemical companies and their trade associations manufacturing doubt via an array of techniques, resulting in agencies such as the U.S. Environmental Protection Agency (EPA) dropping certain provisions from rulemaking, ignoring scientific consensus, and keeping chemicals on the market—and in the environment—that many scientists say should be entirely banned. The authors produced the article in response to this webinar to discuss how to ensure that U.N. panels dealing with global crises get the most sound scientific advice conducted by the International Panel on Chemical Pollution. Over the last four decades or so, the notion that conflicts of interest affect the validity of scientific research and professional opinions has been steadily eroded. Regulators wallow in compromised research, hamstrung by political pressure and […]

(Beyond Pesticides, December 14, 2023) It has been reported that the U.S. Environmental Protection Agency (EPA) is again considering allowing the use of the highly neurotoxic, carbamate insecticide aldicarb for use in Florida citrus, 13 years after the agency and the chemical’s manufacturer, Bayer Crop Science, announced that it was being banned (technically voluntarily canceled). A version of the current EPA proposal and the resource-intensive review process in EPA’s Office of Pesticide Programs—all being done at taxpayers’ expense—was rebuffed, first by the Florida Department of Agriculture and Consumer Services (April 2021), then by a U.S. Court of Appeals (June 2021). Internal EPA emails, as reported in The New Lede (November 21, 2023), expose the extent to which the agency’s science and political staff have tried to downplay aldicarb’s adverse health and environmental outcomes in order to meet the EPA’s broad, and often described as loose, risk parameters.  This Daily News piece on aldicarb is part of an ongoing story of the politicization of science by political appointees to an agency that is charged with protecting public health and the environment. The degree to which agency scientific staff are complicit in advancing agency positions that are not supported by the scientific […]

(Beyond Pesticides, December 13, 2023) A study published in Environmental Health finds occupational (work-related) exposure to pesticides increases the risk of endometrial (uterine) cancer development. Endometrial cancer is the most common cancer of the female reproductive system and the fourth most common cancer among women, primarily affecting the uterine lining rather than the uterus itself, like uterine sarcoma. Despite data predicting the disease rate to increase, few studies evaluate the connection environmental contaminants have on endometrial cancer occurrence. Like most cancers, non-genetic factors account for a majority of endometrial cancer risk, including diabetes, age, contraceptive (birth-control) use, and hormone (endocrine) disruption. However, three percent of all cases are hereditary, primarily from Lynch syndrome. The study notes, “Identifying other modifiable risk factors may help develop strategies to reduce the expected increasing incidence of these neoplasms.” Many pesticides have a long history associated with endocrine-disrupting properties that induce various molecular changes, prompting disease development. The International Agency for Research on Cancer (IARC) classifies many of these chemicals as potent carcinogens in animal studies. Cancer development also depends on genetic susceptibility, as impaired genes responsible for xenobiotic detoxification (elimination) increase disease risk sensitivity. Adding to the science, a review published in Environmental Exposure, Biomonitoring, and Exposure […]

(Beyond Pesticides, December 8, 2023) Nine pesticides have been found in nearly 40% of nonorganic conventional baby foods tested, according to a study conducted by Environmental Working Group (EWG). The study found no residues of the pesticides studied in a sample of certified organic baby food. While the study finds no traces of the highly neurotoxic insecticide chlorpyrifos, associated with brain damage in children, the chemical has been allowed back on the agricultural market after being removed in 2021—raising an alarm for parents who purchase baby food with ingredients grown in chemical-intensive (“conventional”) agriculture. In November 2023, a three-judge panel of the Eighth Circuit Court of Appeals reversed a 2021 U.S. Environmental Protection Agency (EPA) decision to ban chlorpyrifos’ agricultural uses, which came after a 2021 Ninth Circuit Court of Appeals decision found that the agency’s inaction violated federal pesticide law. Because of its neurotoxic effects on children, EPA had in 2000 negotiated Dow Chemical’s voluntary cancellation of most residential uses of the chemical, but left virtually all of the chemical’s agricultural uses in place. While the EWG study focuses on pesticide residues in food and the hazards associated with ingestion of dangerous chemicals, raising alarms, purchasing baby food processed with nonorganic […]

(Beyond Pesticides, December 7, 2023) A new review published in Ecotoxicology reiterates what past studies have repeatedly stated: the herbicide paraquat (PQ) has profound adverse effects on wildlife at environmentally relevant concentrations. Moreover, these adverse effects span beyond the wilderness, as exposure to this highly toxic herbicide also impacts the health of people working with this chemical (e.g., pesticide applicators) or living adjacent to areas of chemical use. Current data gaps regarding the effects of environmentally relevant concentrations and exposure times, population- or ecosystem-level effects, and biomagnification potential contribute to the uncertainty of predicting risk from environmental PQ exposure. Furthermore, Beyond Pesticides has previously pointed out deficiencies in the U.S. Environmental Protection Agency’s (EPA) ecological risk assessments for paraquat, highlighting failures to perform complete evaluations of the impacts of pesticides on threatened and endangered species. All this occurs amid documented threats to biodiversity from the combined effects of pesticides and climate change.  The review investigated paraquat in the environment, the chemical’s toxicity to nontarget species, and significant data gaps. Overall, the long-term risks of environmental PQ contamination for human and ecological communities can be challenging since the potential chronic effects from extended use are nearly unstudied. Most concerning is that PQ is […]

Upcoming EPA Review of Nitrates in Waterways Raises Health and Environmental Questions About Synthetic Nitrogen Fertilizer Use. In  a quiet reversal of a 2018 Trump administration decision, EPA is resuming an evaluation of the health impacts of nitrate in water, reflecting the long-standing and mounting evidence of synthetic nitrogen’s adverse effects on human health and the environment, particularly in vulnerable communities.

(Beyond Pesticides, December 4, 2023) With a history of neglect of farmworker protection in the workplace, advocates are pointing to the need for ensuring stringent enforcement of regulations that are expected to take effect under the Pregnant Workers Fairness Act (PWFA) this month. In addition to weak laws and protections that typically exempt farmworkers, enforcement for farmworker protections that do exist has been lacking. A report on enforcement of wage and hour law under Wage and Hour Division of the U.S. Department of Labor (DOL) has documented diminished capacity to detect and enforce against violations. A report by the Economic Policy Institute (2020) shows the dramatic failures of DOL, which is underfunded and understaffed to enforce the law. As the agency charged with operationalizing the new law to protect farmworkers, the Equal Employment Opportunity Commission (EEOC) will be up against a federal pesticide law enforcement system that is dependent by agreements with state agencies, mostly departments of agriculture, that have a history of failing to enforce the limited protections provided for farmworkers. The EEOC is headquartered in Washington, D.C. and operates 53 field offices in every part of the country. Farmworkers have endured a long history of discrimination in the United […]

With the elevated adverse impacts associated with pesticides and reproductive health, the Pregnant Workers Fairness Act (PWFA) law may be used to improve protections for farmworkers and other high-risk employees.

(Beyond Pesticides, November 15, 2023) A study previously published in the Federation of American Societies for Experimental Biology (FASEB) is drawing renewed attention to the gut microbiome in the scientific community. The study, involving a team including Demetrio Sierra-Mercado, PhD, of the University of Puerto Rico School of Medicine, initially established a link between glyphosate exposure and increased anxiety and fear-related behavior in rats. Glyphosate, a widely-used herbicide, has been detected in trace amounts in fruits, vegetables, grains, and other food and beverages, according to the U.S. Environmental Protection Agency (EPA). Originally deemed safe for humans due to the way it interacts with the shikimic acid pathway—a metabolic route that is absent in humans—glyphosate’s indirect effects on human health are now under scrutiny as the research linking it to anxiety-like behavior grows.  Dr. Sierra-Mercado’s team is expanding on his previous research to take a closer look at the compound’s potential disruption of the gut microbiome, which plays a pivotal role in regulating both physical and mental health. His upcoming study, anticipated in August 2024, aims to delve into the intricate relationship between glyphosate exposure and the gut-brain axis, with a focus on how this may influence neurological and emotional health […]

(Beyond Pesticides, November 14, 2023) One of the Environmental Protection Agency’s (EPA) strongest tools for avoiding responsibility is delay—a tactic that kept cancellation of the neurotoxic pesticide chlorpyrifos at bay for 21 years—until May 2021, when a three-judge panel of the Ninth Circuit Court of Appeals, responded to a petition filed in 2007 by the Natural Resources Defense Council, Pesticide Action Network, and numerous other groups. The Ninth Circuit ordered the agency to quit lollygagging and acknowledge chlorpyrifos’s threat to human health, something the agency had acknowledged already. The Ninth Circuit instructed EPA to either revoke the “safe” tolerances the agency had set for chlorpyrifos’s residue in various foods or demonstrate that they are actually safe. Finally capitulating, EPA issued a final rule in August 2021 revoking all food tolerances for the neurotoxicant. Tell your governor and mayor to adopt policies that support organic land management.  This looked like progress until February 2022, when a different set of petitioners—pesticide companies, U.S. farmer groups, and other countries’ agricultural interests—filed an action in the Eighth Circuit Court of Appeals. On November 3 of this year, a three-judge panel of the Eighth Circuit reversed EPA’s decision, thereby neutralizing the Ninth Circuit’s opinion. Chlorpyrifos, […]

(Beyond Pesticides, November 7, 2023) Two decades after the introduction of genetically engineered, herbicide-resistant crops and the consequential exponential growth in weed killers, Brazil is seeing an increase in childhood cancer. This is the conclusion reached in a comprehensive study spanning 15 years (2004-2019), “Agriculture Intensification and Childhood Cancer in Brazil,” published in Proceedings of the National Academy of Sciences (PNAS) in October. For the past 20 years, soybean herbicides have been killing and sickening children in the Cerrado and Amazon regions–where soybean cultivation is concentrated. The study reveals a link between an increase in soy cultivation and a spike in cases of acute lymphoblastic leukemia (ALL), the most common cancer affecting children, among indirectly exposed populations. Researchers identify pesticide-contaminated drinking water as the driving force behind the increased cancer rates occurring downstream from soybean sites.  In 2003, Brazil legalized its first official genetically modified (GM) crop, welcoming the era of GM soybeans and sparking a radical transformation in its agricultural landscape–for better or worse. The introduction of Monsanto’s Roundup Ready soybean seed promised farmers an efficient and herbicide-resistant alternative to traditional crops. A significant shift occurred in the areas dedicated to soy cultivation in the Cerrado region, tripling from […]

(Beyond Pesticides, November 1, 2023) A study published in Environmental Health Perspective finds the risk of acute childhood leukemia (AL), specifically acute lymphoblastic leukemia (ALL), slightly increases with exposure to pesticides (i.e., insecticides and herbicides) from uses on vines, a crop subject to intensive pesticide use. Within 1 kilometer [km] of vineyards, the risk of ALL among children increases in areas with a higher density of vines. Although medical advancements in disease survival are more common nowadays, childhood AL remains the secondary cause of child mortality following physical injury. Furthermore, childhood leukemia survivors can suffer from chronic or long-term health complications that may be life-threatening. The etiology or cause of childhood AL involves the interaction of multiple components, including lifestyle and genetics; emerging evidence indicates that environmental contaminants (e.g., pesticides, air pollution, solvents, diet, etc.) play a role in disease. Pesticide contamination is widespread in all ecosystems, and chemical compounds can accumulate in human tissues, resulting in chronic health effects. Children are particularly vulnerable to the impacts of pesticide exposure as their developing bodies cannot adequately combat exposure effects. Already, studies find low levels of pesticide exposure during pregnancy or childhood cause adverse health effects, from metabolic disorders to mental and physical disabilities. Moreover, […]

(Beyond Pesticides, October 31, 2023) With cooler weather setting in and people heading indoors and closing windows, the issue of COVID-19 transmission escalates, as do concerns about toxic chemicals filling the indoor ambient air. As a recent segment of 60 Minutes (October 29, 2023) stresses, COVID-19 spreads elevated public concern and understanding about the importance of ventilation, filtration, and air exchange to indoor air quality. Unfortunately, the concerns about indoor air are not limited to COVID-19 as volatile organic compounds (VOCs) invade most spaces where people live and work. These invisible toxic substances can be found in common household products, furniture, mattresses, and more, including pesticides in and around the house. Recognizing the risks associated with VOCs and the potentially hazardous off-gassing process is crucial for protecting public health.  VOCs are a group of chemicals that can easily vaporize into the air at room temperature. These compounds are found in many everyday items, including furniture, cleaning products, pesticides, cosmetics, and even air fresheners. Some household products, particularly pesticides, can introduce their own set of risks in addition to the risks they pose due to their VOC content. VOCs can range from harmless to harmful, and their presence can have a […]

(Beyond Pesticides, October 30, 2023) TAKE ACTION. It is said that the definition of insanity is doing the same thing over and over again and expecting a different result. And so it goes with the U.S. Environmental Protection Agency’s (EPA) proposal to register a new genetically engineered pesticide for the Colorado Potato Beetle (CPB); this time with a pesticide that has not been fully evaluated for its adverse effects to people and the environment. [Submit a public comment before comment period ends today, October 30, 2023.] Chemical-intensive agriculture has failed to control CPB since resistance to DDT was identified in 1952 and has continued with every family of pesticides since then. CPB has been dubbed the billion-dollar-bug because of the investment in failed attempts of chemical manufacturers to control the insect, the profits generated by chemical companies despite this failure, and the resulting losses for chemical-intensive farmers—not to mention government expenditures for the registration of chemicals that have short efficacy, pollution costs associated with chemical production and use, and lost ecosystem services. But, EPA is at it again, registering a new novel pesticide active ingredient, Ledprona, which raises the stakes on potential harm. The only winners in this ongoing failure […]

(Beyond Pesticides, October 27, 2023) In a typical move, EPA proposes to greenlight a type of genetic engineering to solve a problem created by the industrial paradigm for pest control, i.e. vast acreages of monoculture treated with millions of tons of toxic pesticides leading to rapid resistance among crop pests. In this case EPA wants to approve using a nucleic acid—double-stranded RNA (dsRNA)–called “interfering RNA,” or RNAi—to silence a gene crucial to the survival of the Colorado Potato Beetle (CPB), the scourge of potato farmers around the world. But EPA has skipped over important steps in its decision-making process and rushed to judgment. Like chemical pesticides, genetically-based pesticides are regulated under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA). In 2020, Massachusetts-based GreenLight Biosciences applied for registration of its RNAi active ingredient, Ledprona, and its end-use product, Calantha. The company executive heading the effort is an alumnus of Monsanto and several other major chemical companies. Last May EPA granted GreenLight an Experimental Use Permit (EUP) authorizing field studies in states that produce tons of potatoes. A mere five months later, EPA announced its decision to approve the registration based almost entirely on incomplete EUP data and giving the public very […]

(Beyond Pesticides, October 26, 2023) The increasing prevalence of neurodevelopmental disorders (NDDs) in the United States has raised concerns about the impact of toxic exposures on child development. A comprehensive review by Devon Payne-Sturges, PhD, and colleagues in Environmental Health Perspectives analyzes the literature about disparities in NDDs in vulnerable and marginalized populations. The review investigates over 200 studies and reveals that fewer than half of these studies actually examine disparities, and most fail to provide a rationale for their assessments. The authors also offer practical suggestions for improving future research, including better methods for characterizing race and socioeconomic status and interpreting effect modification in environmental epidemiologic studies of health disparities. Associate Professor Devon Payne-Sturges, PhD, at the University of Maryland’s School of Public Health, one of the lead authors of the study and a former policy specialist at the U.S. Environmental Protection Agency (EPA) said, “FDA and EPA can act now—not later—to protect families from neurotoxic chemicals in consumer products and in the environment.” Tanya Khemet Taiwo, PhD, the other lead author and assistant professor at Bastyr University in Seattle said, “We need more stringent environmental standards to address pollution that is disproportionately impacting low-income communities and communities of […]