(Beyond Pesticides, January 19, 2024) A study published in Environmental Health Perspective is one of the first to indicate a link between exposure to the herbicides 2,4-D and glyphosate and the impairment of behavioral performance (i.e., attention/inhibitory control, memory/learning, language, visuospatial processing, and social perception). These adverse effects associated with the neurotoxic impacts of pesticides on behavior have been previously documented. For example, a study in August 2023 finds oral intake (e.g., eating contaminated foods), inhalation, and dermal exposure to glyphosate lowered cognitive function scores, increased the likelihood of severe depressive symptoms, and impaired auditory (hearing) function. Although previous studies find neurotoxic effects from exposure to these herbicides, very few until now have evaluated how this neurotoxic exposure impacts neurotypical behavior among youth (children and teenagers). The ubiquitous use of glyphosate and 2,4-D use in agriculture—which leaves residues of the toxic chemicals in food and in public areas (e.g., parks and walkways) creates a creates a significant risk for exposure. Glyphosate is already implicated in or proven to lead to the development of numerous health anomalies, including cancer, while 2,4-D also has a range of potential hazards, including cancer. Therefore, studies like this help local and government officials make holistic decisions regarding the use […]

(Beyond Pesticides, January 9, 2024) A “landscape-level” study finds that typical risk assessment studies used by the U.S. Environmental Protection Agency (EPA) and European regulators fail to “safeguard bees and other pollinators that support agricultural production and wild plant pollination.” The study, published in Nature (November 2023), evaluates the health of bumble bees (Bombus terrestris) as a sentinel species placed in 106 agricultural landscapes across Europe. The authors’ conclusions challenge “the current assumption of pesticide regulation—that chemicals that individually pass laboratory tests and semifield trials are considered environmentally benign”—calling into question EPA’s persistent failure to adequately regulate mixtures of chemicals to which organisms are exposed in the real world. This study adds to the body of science on pesticide mixtures adversely affecting bee and pollinator health. See here, here, and here. The failure to capture real-world exposure to pesticide mixtures in its regulatory assessments extends to EPA’s systemic failure to evaluate a range of serious adverse impacts, as noted by the agency’s Office of Inspector General (OIG) report. And, aquatic environments also have documented mixtures of pesticides, with the U.S. Geological Survey finding 90 percent of water samples containing at least five or more different pesticides. “We can take no comfort […]

(Beyond Pesticides, January 3, 2024) A study published in Environmental Health Perspectives finds elevated, chronic exposure to glyphosate throughout one’s lifetime increases the risk of mosaic loss of chromosome Y (loss of chromosome Y occurs to many men in some cells due to aging [mLOY]) that impacts a noticeable fraction of cells. Although the loss of this sex chromosome does not cause cell death, like the loss of autosomal chromosomes, the risk of mLOY is a biomarker for genotoxicity (the damage of genetic information within a cell causing mutations from chemical exposure, which may lead to cancer) and expansion of cellular response to glyphosate, resulting in the precursor for hematological (blood) cancers. This study is one of the first to identify sex-specific chromosome degradation, with stark evidence demonstrating links to various cancers, including non-Hodgkin lymphoma. The International Agency for Research on Cancer (IARC) has classified the glyphosate as a probable carcinogen or cancer-causing chemical. However, the U.S. Environmental Protection Agency’s (EPA) allowance of widespread use of glyphosate allows for adverse impacts, especially among vulnerable individuals, like pregnant women, infants, children, and the elderly. Glyphosate exposure levels and resulting residues in urine has been documented with recent data showing that four out of five (81.6%) […]

(Beyond Pesticides, December 7, 2023) A new review published in Ecotoxicology reiterates what past studies have repeatedly stated: the herbicide paraquat (PQ) has profound adverse effects on wildlife at environmentally relevant concentrations. Moreover, these adverse effects span beyond the wilderness, as exposure to this highly toxic herbicide also impacts the health of people working with this chemical (e.g., pesticide applicators) or living adjacent to areas of chemical use. Current data gaps regarding the effects of environmentally relevant concentrations and exposure times, population- or ecosystem-level effects, and biomagnification potential contribute to the uncertainty of predicting risk from environmental PQ exposure. Furthermore, Beyond Pesticides has previously pointed out deficiencies in the U.S. Environmental Protection Agency’s (EPA) ecological risk assessments for paraquat, highlighting failures to perform complete evaluations of the impacts of pesticides on threatened and endangered species. All this occurs amid documented threats to biodiversity from the combined effects of pesticides and climate change.  The review investigated paraquat in the environment, the chemical’s toxicity to nontarget species, and significant data gaps. Overall, the long-term risks of environmental PQ contamination for human and ecological communities can be challenging since the potential chronic effects from extended use are nearly unstudied. Most concerning is that PQ is […]

(Beyond Pesticides, December 4, 2023) With a history of neglect of farmworker protection in the workplace, advocates are pointing to the need for ensuring stringent enforcement of regulations that are expected to take effect under the Pregnant Workers Fairness Act (PWFA) this month. In addition to weak laws and protections that typically exempt farmworkers, enforcement for farmworker protections that do exist has been lacking. A report on enforcement of wage and hour law under Wage and Hour Division of the U.S. Department of Labor (DOL) has documented diminished capacity to detect and enforce against violations. A report by the Economic Policy Institute (2020) shows the dramatic failures of DOL, which is underfunded and understaffed to enforce the law. As the agency charged with operationalizing the new law to protect farmworkers, the Equal Employment Opportunity Commission (EEOC) will be up against a federal pesticide law enforcement system that is dependent by agreements with state agencies, mostly departments of agriculture, that have a history of failing to enforce the limited protections provided for farmworkers. The EEOC is headquartered in Washington, D.C. and operates 53 field offices in every part of the country. Farmworkers have endured a long history of discrimination in the United […]

With the elevated adverse impacts associated with pesticides and reproductive health, the Pregnant Workers Fairness Act (PWFA) law may be used to improve protections for farmworkers and other high-risk employees.

(Beyond Pesticides, November 15, 2023) A study previously published in the Federation of American Societies for Experimental Biology (FASEB) is drawing renewed attention to the gut microbiome in the scientific community. The study, involving a team including Demetrio Sierra-Mercado, PhD, of the University of Puerto Rico School of Medicine, initially established a link between glyphosate exposure and increased anxiety and fear-related behavior in rats. Glyphosate, a widely-used herbicide, has been detected in trace amounts in fruits, vegetables, grains, and other food and beverages, according to the U.S. Environmental Protection Agency (EPA). Originally deemed safe for humans due to the way it interacts with the shikimic acid pathway—a metabolic route that is absent in humans—glyphosate’s indirect effects on human health are now under scrutiny as the research linking it to anxiety-like behavior grows.  Dr. Sierra-Mercado’s team is expanding on his previous research to take a closer look at the compound’s potential disruption of the gut microbiome, which plays a pivotal role in regulating both physical and mental health. His upcoming study, anticipated in August 2024, aims to delve into the intricate relationship between glyphosate exposure and the gut-brain axis, with a focus on how this may influence neurological and emotional health […]

(Beyond Pesticides, October 26, 2023) The increasing prevalence of neurodevelopmental disorders (NDDs) in the United States has raised concerns about the impact of toxic exposures on child development. A comprehensive review by Devon Payne-Sturges, PhD, and colleagues in Environmental Health Perspectives analyzes the literature about disparities in NDDs in vulnerable and marginalized populations. The review investigates over 200 studies and reveals that fewer than half of these studies actually examine disparities, and most fail to provide a rationale for their assessments. The authors also offer practical suggestions for improving future research, including better methods for characterizing race and socioeconomic status and interpreting effect modification in environmental epidemiologic studies of health disparities. Associate Professor Devon Payne-Sturges, PhD, at the University of Maryland’s School of Public Health, one of the lead authors of the study and a former policy specialist at the U.S. Environmental Protection Agency (EPA) said, “FDA and EPA can act now—not later—to protect families from neurotoxic chemicals in consumer products and in the environment.” Tanya Khemet Taiwo, PhD, the other lead author and assistant professor at Bastyr University in Seattle said, “We need more stringent environmental standards to address pollution that is disproportionately impacting low-income communities and communities of […]

(Beyond Pesticides, September 29, 2023) In unsurprising news, the Environmental Protection Agency (EPA) has reversed itself and decided not to ban a dangerous pesticide: tetrachlorovenphos (TCVP) used in pet flea collars and other flea products. This is despite its own earlier decision to ban TCVP in pet collars and scathing criticism of its methods and conclusions by the courts. First registered in 1966, TCVP belongs to the notoriously toxic organophosphate chemical family and is classified by the World Health Organization as “possibly carcinogenic to humans.” It was originally registered to Shell Chemical, then to E.I. duPont de Nemours, then to Hartz Mountain Corporation and Fermenta Animal Health Company.  Early on, it was registered for use on food crops and livestock, but the crop uses were voluntarily de-registered in 1987. It is still widely used on pets and farm animals. In 1995, EPA issued the opinion that “all uses of tetrachlorvinphos, with the exception of oral feed-through larvicide treatment to livestock intended for food use, will not cause unreasonable risk to humans or the environment.” Since then, the agency has contorted itself repeatedly to allow TCVP to remain on the market. There is little research available on TCVP’s human health effects; the […]

(Beyond Pesticides, September 25, 2023) It happens twice a year. The transparent process of a stakeholder board of farmers, consumers, environmentalists, a scientist, retailer, and certifier get together as members of the National Organic Standards Board (NOSB) and vote on allowable materials and standards in organic agriculture. This Congressionally mandated board has authorities not often given to people outside of government—authorities to determine what should be allowed in organic food production, under assessments of synthetic and natural substances. And the underlying law that makes this happen, the Organic Foods Production Act (OFPA), stipulates that the Secretary of Agriculture may not allow synthetic and prohibited natural materials unless they are recommended by the NOSB. The National Organic Standards Board (NOSB) is receiving written comments from the public, which must be submitted by September 28, 2023. The values and principles embedded in OFPA far exceed the standards of health and environmental protection of any other health and environmental laws, which establish risk mitigation measures to determine allowable harm, under a set of guiding standards that require the board to (i) protect health (from production of inputs to their disposal), (ii) ensure compatibility with organic systems (with determinations that inputs do not hurt […]

(Beyond Pesticides, September 6, 2023) In late August, the Office of the Inspector General (OIG) at the U.S. Environmental Protection Agency (EPA) released a report concluding that EPA “took a siloed approach” to the cumulative impacts of chemical exposures and the disproportionate nature of those exposures. This approach keeps different parts of the EPA from coordinating their efforts and hinders understanding of the breadth and depth of chemical exposures. OIG reached this disturbing finding despite the issuance of several executive orders by President Biden requiring EPA to develop policies and actions to assess cumulative impacts of chemical exposures across departments, laws, and environmental media (air, water, bodies, food etc.) and to pay more attention to environmental justice. Beyond Pesticides has stressed that the whole constellation of chemical exposures and effects should be considered when governments set public policies and regulations. Just last March, Daily News covered another OIG report castigating EPA for betraying its mission by failing to address the fact that very high levels of per- and polyfluoroalkyl compounds known as “forever chemicals” have been found in some common pesticides. OIG also berated EPA for succumbing to Donald Trump’s interference with setting toxicity values for the “forever chemical” perfluorobutane […]

(Beyond Pesticides, August 23, 2023) The use of pesticides on pets for fleas and ticks (parasiticides) has been traced to environmental contamination in a study that confirms earlier work both by the authors and internationally, according to researchers Rosemary Perkins, a veterinary surgeon, and David Goulson, PhD at the University of Sussex. The results are published in their recent study, “To flea or not to flea: survey of UK companion animal ectoparasiticide usage and activities affecting pathways to the environment,” which concludes that, “[T]he potential cumulative impact of parasiticide emissions [into the environment] from many millions of pets treated multiple times each year is of serious concern.” The UK provides an opportunity to pinpoint water contamination from pet use for ectoparasites (e.g., fleas and ticks) of hazardous pesticides since, unlike in the U.S., the country has banned outdoor use of those chemicals commonly detected—the insecticides fipronil and imidacloprid (the same neonicotinoid bug killer tied to devastating losses of bees and other organisms). These findings confirm the historical peer reviewed scientific literature and defy the assumption of regulators that home or veterinary use of pesticides do not reach levels of concern for environmental contamination, either through exposure from down-the-drain (DTD) contamination […]

(Beyond Pesticides, August 11, 2023) Reinforcing earlier findings, a systematic review published in Chemosphere finds the popular herbicide glyphosate and its formulations (glyphosate-based formulations-GBF) exhibit five out of the ten key characteristics (KC) of carcinogens (cancer-causing chemicals). Specifically, glyphosate exhibits strong evidence of genotoxicity, epigenetic alterations (heritable changes in gene expression), oxidative stress, chronic inflammation, endocrine disruption, and disturbs gut microbiota implicated in lymphomagenesis (growth and development of lymphoma). Although organizations like the International Agency for Research on Cancer (IARC) designate glyphosate as a probable human carcinogen, and scientific literature supports the findings on these adverse effects purported by glyphosate, the chemical remains on the U.S. market in various formulations. Glyphosate is the most commonly used active ingredient worldwide, appearing in many herbicide formulas, not just Bayer’s (formerly Monsanto) Roundup®. The use of this chemical has been increasing since the inception of crops genetically modified to tolerate glyphosate over two decades ago. The toxic herbicide readily contaminates the ecosystem with residues pervasive in food and water commodities. In addition to this study, literature proves time and time again that glyphosate has an association with cancer development, as well as human, biotic, and ecosystem harm. Therefore, advocates point to the need for national policies to reassess hazards associated with […]

(Beyond Pesticides, July 24, 2023) Sewage sludge, also known as biosolids, is a byproduct of sewage treatment and is used as a source of organic matter for amending soil in nonorganic agriculture and landscaping. EPA has published a list of 726 chemicals found in biosolids in the National Sewage Sludge Surveys. This list does not include the per- and polyfluoroalkyl substances (PFAS), which are emerging contaminants of biosolids. Tell your Governor and local officials to ban the use of biosolids in farms and parks, until there is adequate testing of toxic residues—which does not currently exist. In addition to PFAS (also referred to as “forever chemicals”), persistent toxic pollutants found in biosolids include: inorganic chemicals such as metals and trace elements; organic chemicals such as polychlorinated biphenyls or PCBs, dioxins, pharmaceuticals, and surfactants; and pathogens including bacteria, viruses, and parasites. Regulation of biosolids by the U.S. Environmental Protection Agency (EPA) has been found by the EPA Office of Inspector General (OIG), in its report EPA Unable to Assess the Impact of Hundreds of Unregulated Pollutants in Land-Applied Biosolids on Human Health and the Environment, to be inadequate. Lacking sufficient oversight at the federal level, action to protect health and the environment falls […]

The introduction of the Agricultural Labeling Uniformity Act in the U.S. House of Representatives, expected to be a part of the Farm Bill negotiations, is raising the specter (yet again) of undermining local and state authority to protect the health of their residents from pesticides—effectively overturning decades of Supreme Court precedent.

(Beyond Pesticides, May 18, 2023) A study published in Food and Chemical Toxicology finds pesticide residues in beehive products pose a safety risk from dietary consumption. Beehive products (i.e., bee bread, propolis, beeswax, and royal jelly) from beekeeping or apiculture are said to have nutraceutical (health and medicinal benefits) properties. However, a wide range of pesticide residues (i.e., tau-fluvalinate, coumaphos, chlorfenvinphos, chlorpyrifos, and amitraz), especially acaricides for killing ticks and mites in hives, may accumulate in beehive products up to concentrations that pose a potential health risk. Environmental contaminants like pesticides are ubiquitous in the environment, with 90 percent of Americans having at least one pesticide compound in their body. Many of these chemical compounds remain in soils, water (solid and liquid), and the surrounding air at levels exceeding U.S. Environmental Protection Agency (EPA) standards. Therefore, individuals still encounter pesticide compounds at varying concentrations, adding to the toxic body burden of those harmful chemicals currently in use. The research methodology includes a review of the scientific literature on pesticide contamination in hive products and a dietary risk assessment. The risk assessment calculation uses scientific studies to determine the recommended daily intake values and concentration data. Researchers compare exposure values in products to health-based guidance, determining the potential acute and […]

(Beyond Pesticides, April 7, 2023) A  petition to the U.S. Environmental Protection Agency (EPA) implores the agency to halt the practice of allowing pesticides banned in the U.S. to be exported to other countries without any consent from relevant governmental authorities in those nations. The two petitioners—the Center for Biological Diversity (CBD) and the Center for International Environmental Law (CIEL)—are focusing on a longstanding practice of U.S. pesticide manufacturers and brokers, who sell toxic pesticide products that fail to qualify for EPA registration domestically to entities nearly anywhere in the world (except where the products are specifically prohibited). As Beyond Pesticides has noted, this is a dangerous and environmentally unjust practice and has for decades urged Congress and EPA to forbid it. According to the CIEL press release on the matter, the petition was motivated by the reality that banned or voluntarily withdrawn pesticides “are routinely exported to countries that often have limited resources or capacity to assess and regulate chemical risks,” and that the “practice has directly fueled the influx of extremely hazardous pesticides to countries in the Global South, where they disproportionately harm Indigenous peoples and vulnerable and marginalized communities.” The organizations emphasize that, for example, more than four-fifths […]

(Beyond Pesticides, March 31, 2023) A report from the Office of the Inspector General (OIG) for the U.S. Environmental Protection Agency (EPA) identifies the most recent event in the very long chronicle of EPA dysfunction that — put charitably — constitutes failures to enact its mission, and more accurately, sometimes crosses the line into malfeasance. In the report, OIG concludes that EPA’s 2021 PFBS Toxicity Assessment failed to “uphold the agency’s commitments to scientific integrity and information quality,” and that the agency’s actions “left the public vulnerable to potential negative impacts on human health.” As reported by The Guardian, “Trump administration appointees at . . . EPA meddled in agency science to weaken the toxicity assessment of a dangerous chemical.” Last year, Beyond Pesticide concerns about the myriad risks and harms of pesticides intersected with those about the PFAS (Per- and Polyfluorinated Substances) family of chemical compounds, of which PFBS is a member, when a study found very high levels of PFAS in multiple pesticide products. The EPA OIG explains why it undertook the evaluation that led to this report: “to determine whether the EPA followed applicable policies and procedures to develop and publish the January 19, 2021 perfluorobutane sulfonic acid […]

(Beyond Pesticides, March 13, 2023) The United Nations has just announced on March 4, 2023, an agreement on a new high seas treaty. The treaty, which must be adopted by member states and then ratified by at least 60 countries to take effect could be a critical development for meeting the UN’s COP15 “30 by 30” goal of protecting 30% of the world’s land and sea by 2030 to slow and arrest global biodiversity losses. The treaty represents a step toward implementation of President Biden’s “America the Beautiful Initiative” set in 2021, proclaiming “the first-ever national conservation goal” established by a President –a goal of conserving at least 30 percent of U.S. lands and waters by 2030.” However, he U.S. has a poor track record on approval of UN environmental treaties; approval requires a two-thirds majority affirmative vote in the Senate, and failure on that would block a Presidential signature and ratification. Meanwhile, a report just reissued by an international coalition of scientists led by Boston College’s Global Public Health Program and Global Observatory on Planetary Health and the Centre Scientifique de Monaco documents the widespread and growing pollution of the ocean. The full report, “Human Health and Ocean Pollution,” is […]

(Beyond Pesticides, February 15, 2023) Areas designated to protect insects fail to do so for over 75 percent of global species, according to a study, “Three-quarters of insect species are insufficiently represented by protected areas,” published in the online journal One Earth. Protected Areas (PAs) act as a safeguard for biodiversity. However, PAs in North America, Eastern Europe, Southeast Asia, and Australia do not meet the minimum coverage requirements to safeguard global insect species assessed in the study. PAs are discussed in the 2020 Nature article, “Area-based conservation in the twenty-first century,” in which the authors state that, in view of the global biodiversity crisis, national governments must do much more to increase protected areas with “coverage across different elements of biodiversity (ecoregions, 12,056 threatened species, ‘Key Biodiversity Areas’ and wilderness areas) and ecosystem services (productive fisheries, and carbon services on land and seas).” The authors write, citing the UN Convention on Biological Diversity (to which the United States is not a signatory), “To be more successful after 2020, area-based conservation must contribute more effectively to meeting global biodiversity goals—ranging from preventing extinctions to retaining the most-intact ecosystems—and must better collaborate with the many Indigenous peoples, community groups and private initiatives […]

(Beyond Pesticides, February 7, 2023) U.S. Senator Cory Booker (D-N.J.) reintroduced legislation last week to increase protections against exposure to toxic pesticides. The Protect America’s Children from Toxic Pesticides Act of 2023 (PACTPA), S.269, addresses many of the controversial issues with the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), which governs the registration and use of pesticides in the U.S. This major reform legislation tackles some of the documented deficiencies in the regulation of pesticides and removes a number of loopholes in the law. The legislation, introduced with Senators Kirsten Gillibrand (D-NY), Bernie Sanders (D-VT), Elizabeth Warren (D-MA) and Brian Schatz (D-HI), also includes a ban on all organophosphate and neonicotinoid insecticides, as well as  the weed killer paraquat, which is known to cause Parkinson’s disease and lung fibrosis. Despite these reform provisions, the legislation does not touch the core of FIFRA’s pesticide registration process and chart a path for the systemic, transformative change that Beyond Pesticides says is essential to meet the existential challenges of current times—devastating health threats, biodiversity collapse, and the climate crisis. FIFRA, which is under the jurisdiction of the agriculture committees of Congress, has long been criticized for failing to protect the public and workers […]

(Beyond Pesticides, January 9, 2023) The Biden EPA still needs a new vision in order to meet the existential crises in public health, climate change, and biodiversity. The Trump Environmental Protection Agency (EPA) reversed in four years much of the progress made by the EPA in decades. Despite a broad new perspective embodied in President Biden’s Executive Memorandum (EM) Modernizing Regulatory Review issued on his first day in office, the Biden EPA has not adopted a new direction for regulating pesticides. Tell President Biden, EPA, and Congress to adopt a new direction for pesticide regulation. Immediately following his inauguration, President Joe Biden issued the EM, which directs the heads of all executive departments and agencies to produce recommendations for improving and modernizing regulatory review, with a goal of promoting public health and safety, economic growth, social welfare, racial justice, environmental stewardship, human dignity, equity, and the interests of future generations. This EM could reverse the historical trend of status-quo regulatory reviews required by the White House Office of Management and Budget (OMB) that typically support vested economic interests of polluters (e.g., petroleum-based pesticide and fertilizer manufacturers). The President’s EM sets the stage for the adoption of agency policy across government to […]

(Beyond Pesticides, January 6, 2023) Plaintiffs in a recent pesticide lawsuit against the U.S. Environmental Protection Agency (EPA) reprise, in their arguments, a critique proffered repeatedly by Beyond Pesticides: the agency has failed, for many years, to evaluate and regulate endocrine-disrupting pesticides adequately. The suit, according to Progressive Farmer, argues that the 1996 Food Quality Protection Act (FQPA) — legislation that mandated that EPA establish “tolerances” for pesticides in foods and regulate on those bases — required EPA to develop an endocrine disruptor screening program (EDSP) and to implement it by 1999. The litigation goes on to note that “more than twenty-five years after the passage of the FQPA, EPA has yet to implement the EDSP it created and further, has failed to even initiate endocrine testing for approximately 96% of registered pesticides.” Plaintiffs are asking the court, among other requests (see below) to order “EPA to complete all actions required under the FQPA at issue in this case as soon as reasonably practicable, according to a Court-ordered timeline.” Endocrine disruptors are chemicals that can, even at low exposure levels, disrupt normal hormonal (endocrine) function. Endocrine disruptors function by: (1) mimicking the action of a naturally produced hormone, such as estrogen […]