[X] CLOSEMAIN MENU

  • Archives

  • Categories

    • air pollution (11)
    • Announcements (619)
    • Antibiotic Resistance (51)
    • Antimicrobial (25)
    • Aquaculture (32)
    • Aquatic Organisms (51)
    • Artificial Intelligence (1)
    • Bats (21)
    • Beneficials (85)
    • biofertilizers (2)
    • Biofuels (6)
    • Biological Control (37)
    • Biomonitoring (49)
    • Biostimulants (1)
    • Birds (34)
    • btomsfiolone (1)
    • Bug Bombs (2)
    • Cannabis (31)
    • Centers for Disease Control and Prevention (CDC) (15)
    • Chemical Mixtures (27)
    • Children (156)
    • Children/Schools (251)
    • cicadas (1)
    • Climate (50)
    • Climate Change (113)
    • Clouds (1)
    • Clover (1)
    • compost (9)
    • Congress (38)
    • contamination (175)
    • deethylatrazine (2)
    • diamides (1)
    • Disinfectants & Sanitizers (19)
    • Drift (32)
    • Drinking Water (25)
    • Ecosystem Services (49)
    • Emergency Exemption (3)
    • Environmental Justice (195)
    • Environmental Protection Agency (EPA) (635)
    • Events (96)
    • Farm Bill (31)
    • Farmworkers (232)
    • Forestry (6)
    • Fracking (4)
    • Fungal Resistance (8)
    • Generally Recognized As Safe (GRAS) (1)
    • Goats (3)
    • Golf (16)
    • Greenhouse (1)
    • Groundwater (24)
    • Health care (34)
    • Herbicides (66)
    • Holidays (51)
    • Household Use (10)
    • Indigenous People (13)
    • Indoor Air Quality (8)
    • Infectious Disease (4)
    • Integrated and Organic Pest Management (80)
    • Invasive Species (37)
    • Label Claims (57)
    • Lawns/Landscapes (261)
    • Litigation (362)
    • Livestock (16)
    • men’s health (10)
    • metabolic syndrome (3)
    • Metabolites (18)
    • Mexico (1)
    • Microbiata (27)
    • Microbiome (45)
    • molluscicide (1)
    • Nanosilver (2)
    • Nanotechnology (54)
    • National Environmental Policy Act (1)
    • National Politics (390)
    • Native Americans (8)
    • Occupational Health (30)
    • Oceans (13)
    • Office of Inspector General (5)
    • perennial crops (1)
    • Pesticide Drift (189)
    • Pesticide Efficacy (13)
    • Pesticide Mixtures (37)
    • Pesticide Residues (208)
    • Pets (40)
    • Plant Incorporated Protectants (3)
    • Plastic (14)
    • Poisoning (24)
    • President-elect Transition (3)
    • rainwater (1)
    • Reflection (7)
    • Repellent (5)
    • Resistance (129)
    • Rights-of-Way (1)
    • Rodenticide (37)
    • Seasonal (6)
    • Seeds (11)
    • soil health (54)
    • Superfund (5)
    • synergistic effects (50)
    • Synthetic Pyrethroids (20)
    • Synthetic Turf (4)
    • Take Action (654)
    • Textile/Apparel/Fashion Industry (1)
    • Toxic Waste (12)
    • U.S. Supreme Court (7)
    • Volatile Organic Compounds (2)
    • Women’s Health (42)
    • Wood Preservatives (36)
    • World Health Organization (13)
    • Year in Review (3)
  • Most Viewed Posts

Daily News Blog

Archive for the 'Endocrine Disruption' Category


15
Sep

With Global Disease Rates Rising, Do Pesticides Take Some of the Blame? Science Says, “Yes.”

(Beyond Pesticides, September 15, 2022) A review published in Scientific African finds pesticide exposure contributes to the increase in non-communicable diseases (NCDs) in Tanzania, reflecting implications for global health. There are four main NCDs, including cardiovascular diseases, cancers, respiratory diseases, and endocrine-disrupting diseases like diabetes. These diseases have no bacterial, viral, or fungal causes, but are chronic diseases with risk factors like genetics, tobacco/alcohol use, physical activity, and diet, thus lacking transmission between people. However, research is now investigating the role environmental factors play in NCD risks, such as outdoor and indoor air pollution, exposure to chemicals, radiation, and occupation. Regardless of whether working together or separately, these risk factors contribute to NCDs and subsequent health conditions. Non-communicable diseases are on the rise, and the World Health Organization (WHO) classifies non-communicable diseases as the number one cause of death globally, affecting 41 million individuals. Moreover, WHO estimates NCD death rates to increase by 17 percent in the next decade, significantly surpassing deaths from communicable, maternal, perinatal, and nutritional diseases combined. Therefore, the report notes, “This review is informative to the policy, practices, and intervention towards the existing situation of pesticides in Tanzania. In addition, it calls for further investigation of the absence of data […]

Share

01
Sep

Exposure to Synthetic Pyrethroids During Infancy Associated with Developmental Delays in Toddlers

(Beyond Pesticides, September 1, 2022) Low level exposure to synthetic pyrethroid insecticides at 6-8 months of age is associated with language development delays in two-year old toddlers, according to research published in Neurotoxicology this month. This is the latest study to link this class of chemicals to developmental delays in young children. Despite a steady drum of concerning research, the U.S. Environmental Protection Agency (EPA) in 2019 removed a crucial “safety factor” intended to protect children’s health from synthetic pyrethroids, allowing higher levels of the insecticides to be sprayed on food, in homes, and playing fields around the country.   To investigate the impact of synthetic pyrethroids on language development, scientists enrolled 327 expectant mothers in their third trimester. The mothers, all from rural areas of China, were selected if they had no history of significant pesticide exposure or family history of serious disease. Urine samples were taken from the women during pregnancy, and from infants 6-8 months after birth. Scientists analyzed samples for concentrations of three different synthetic pyrethroid breakdown products (metabolites), including 3-phenoxybenzoic acid (3PBA), 4-fluoro-3-phenoxybenzoic acid (4F3PBA), and cis-2,2dibromovinyl-2,2-dimethylcyclopropane-1-carboxylic acid (DBCA). While 3PBA is a metabolite of many synthetic pyrethroids, 4F3PBA a more specific metabolite of cypermethrin, […]

Share

12
Aug

Endocrine Disrupting Chemicals Contribute to Liver Injury, including Toxic PFAS and Pesticides

(Beyond Pesticides, August 12, 2022) Gestational (during pregnancy) exposure to endocrine disrupting chemicals (EDCs) like pesticides, per- and polyfluoroalkyl substances (PFAS), among others, may increase pediatric (child) liver injury and non-alcoholic fatty liver disease (NAFLD) risk, according to a study published in Environmental Health. Past studies associate exposure to EDCs with increased susceptibility to adverse health effects during critical fetal and childhood developmental periods. The World Health Organization (WHO), European Union (EU), and endocrine disruptor expert (deceased) Theo Colborn, Ph.D., classify over 55 to 177 chemical compounds as endocrine disruptors, including various household products like detergents, disinfectants, plastics, and pesticides. Endocrine disruption can lead to several health problems, including hormone-related cancer development (i.e., thyroid, breast, ovarian, prostate, testicular), reproductive dysfunction, and diabetes/obesity that can span generations. Because EDCs are ubiquitous because they are found in many products, studies report that these toxic chemical compounds are detectable in infants, children, and pregnant women. Furthermore, pregnant women can readily transfer compounds to the developing fetus through the placenta. Therefore, it is essential to understand the mechanism behind how harmful chemical exposure induces endocrine disruption during critical developmental periods. Researchers note, “Considering the lack of studies on endocrine disruption and pediatric NAFLD, research like this highlights the need to understand the underlying […]

Share

09
Aug

“Inert” Pesticide Ingredients and Failure to Regulate Raise Dangers for All U.S. Residents

(Beyond Pesticides, August 9, 2022) The most widely used pesticide chemicals in the United States are not listed on product labels, yet pose widespread environmental and public health hazards, according to commentary published this month in Environmental Health Perspectives by two veteran researchers. At issue are adjuvants and so-called “inert” (or “other”) ingredients, chemicals that are added to formulated pesticide products, but do not undergo the same safety reviews as the active ingredient in pesticide products. This donut hole of regulation has permitted, as the commentary shows, millions of pounds of chemicals to be applied in California and throughout the country without proper scientific evaluation of their human health or ecological impact. Researchers first draw a distinction between adjuvant products and inert ingredients in pesticide products. Adjuvants are materials specifically designed to improve the performance of a pesticide spray and are sold separately from formulated pesticide products. Adjuvants are “tank mixed” with a pesticide prior its application. Inert ingredients are any ingredient within a formulated pesticide product that is not designed to prevent, destroy, or repel a pest. Adjuvants and inert ingredients can be the same material – the difference lies in when they are added to a formulated pesticide […]

Share

03
Aug

Scientific Literature Review Again Connects Pesticides and Male Fertility Problems

(Beyond Pesticides, August 3, 2022) A systematic review of scientific studies on pesticides and fertility finds exposure associated with lower semen quality, DNA fragmentation, and chromosomal abnormalities. Published in the journal Andrology, the review is yet another warning from a long string of researchers sounding the alarm over the connection between global fertility and toxic chemical exposure. With data from the U.S. Centers for Disease Control and Prevention (CDC)  indicating roughly 1 in 5 couples are unable to conceive after a year of trying, and trends continuing to slope downwards, it is critical that contributing factors be identified so that protective changes can be made.   After screening over 1,300 studies, researchers narrowed their review down to 64 papers assessing semen parameters and DNA integrity after pesticide exposure. Each study is analyzed for its design, the pesticide investigated,  the population studied, controls, and reproductive effects determined. Pesticides are evaluated for their impacts to sperm quality and DNA integrity based on their chemical class. Organochlorine insecticides, which are all banned but still persistent in soil, air, water, and food in the United States, include a range of impacts to sperm quality. Higher levels of DDT or its breakdown metabolite DDE are […]

Share

21
Jul

Pesticide Exposure Driving Liver Disease through Hormone Disrupting Mechanisms

(Beyond Pesticides, July 21, 2022) Research published in Scientific Reports finds an association between the increasing emergence of nonalcoholic fatty liver disease (NAFLD) and exposure to endocrine (hormone) disrupting chemicals, like organochlorine pesticides (OCPs). It is well-known that traces of legacy (past-use) pesticides, like organochlorines, remain in the environment for decades—possibly centuries, post-final application, as OCPs have greater chemical stability and gradual attenuation. However, these chemicals have profound adverse impacts on human health, especially on the endocrine system. Obesity, insulin resistance, type 2 diabetes, and elevated liver enzyme resulting from endocrine disruption contribute to NAFLD and can lead to liver cirrhosis. Although some, but not all, manufacturing and use of specific OCPs have declined in the U.S., OCPs remain a global issue, as much of the developing world still reports usage. Considering the lack of studies on OCP-induced endocrine disruption and NAFLD, research like this highlights the need to understand the underlying mechanisms that contribute to growing endocrine disease incidents.   The study determined that there is an association between OCP exposure and NAFLD using the fatty liver index (FLI), a predictor of lipid (fat) accumulation in the liver. The researcher collected blood serum to measure the concentration of OCPs, specifically evaluating detectable […]

Share

18
Jul

Take Action: Male Fertility Harmed by Pesticides and EPA Dysfunction

(Beyond Pesticides, July 18, 2022) The failure of the U.S. Environmental Protection Agency (EPA) to meet its statutory responsibility to protect people and wildlife from the dire consequences of exposure to endocrine disrupting chemicals must end. A study published in Toxicology and Applied Pharmacology adds urgency to the need to eliminate endocrine-disrupting pesticides. The authors find that prepubescent exposure to endocrine-disrupting chemicals (EDCs), including pesticides, impairs male reproduction through the interruption of testicular homeostasis and development of reproductive Leydig cells, and can have multigenerational effects. This adds to the long list of scientific articles showing EPA neglect of the devastating effects of widely used pesticides. Tell EPA that pesticide use cannot continue without findings of no endocrine disruption. Tell Congress to ensure that EPA does its job. More than 50 pesticide active ingredients have been identified as endocrine disruptors that mimic the action of a naturally-produced hormone, such as estrogen or testosterone, thereby setting off similar chemical reactions in the body; block hormone receptors in cells, thereby preventing the action of normal hormones; or affect the synthesis, transport, metabolism and excretion of hormones, thus altering the concentrations of natural hormones. Endocrine disruptors have been linked to attention deficit hyperactivity disorder (ADHD), […]

Share

14
Jul

Endocrine-Disrupting Chemicals Impair Juvenile Male Fertility Development and Threatens Future Reproductive Health

(Beyond Pesticides, July 14, 2022) A study published in Toxicology and Applied Pharmacology finds prepubescent exposure to endocrine-disrupting chemicals (EDCs), including pesticides, impairs male reproduction through the interruption of testicular homeostasis and development of reproductive Leydig cells. Endocrine disruptors are xenobiotic (i.e., chemical substances like toxic pesticides foreign to an organism or ecosystem). Many reports demonstrate that exposure to endocrine-disrupting chemicals can adversely affect human, animal—and thus environmental—health by altering the natural hormones in the body responsible for conventional reproductive, physical, and mental development. Scientists and health officials already associate pesticide exposure with a decrease in male fertility, including reduced sperm count, quality, and abnormal sperm development. The presence of pesticides in the body has implications for human health, especially during vulnerable life stages, such as childhood, puberty, pregnancy, and old age. Therefore, it is essential to understand how exposure to toxic chemicals in the environment affects future reproductive success and health. The researchers note, “Recent studies revealed that exposures to EDCs during so-called critical windows of susceptibility (prenatal, prepubertal, pubertal, and aging periods) could disrupt healthy patterns of testes development and homeostasis, which can be demonstrated as an impaired testicular function later in life. However, much more work is needed to understand better the cellular […]

Share

16
Jun

Farmed Salmon Just as Toxic to Human Health as Junk Food

(Beyond Pesticides, June 16, 2022) Farmed salmon serves as an inferior food source, accumulating more toxic chemicals in fatty tissue with fewer healthy nutrient properties based on a study from the University of Bergen, Norway and Alternative Medicine Review. However, the issue of toxic chemical contamination in fish dates back decades with investigations demonstrating high levels of persistent organic pollutants (POPs), including polybrominated diphenyl ethers (PBDEs) flame retardants restricted or banned in the U.S. and U.K., polychlorinated biphenyl (PCBs), dioxin (a by-product of pesticide manufacturing), and ethoxyquin (a pesticide preservative in fish feed). The aquaculture industry (e.g., farmed seafood/fish) repeatedly faces sustainability issues, failing to adhere to environmental regulations and threatening marine health. Extensive use of pesticides in local marine ecosystems has induced coastal habitat loss and increased genetic and health risks to wild marine populations. Moreover, insecticides used to kill salmon parasites (e.g., fish lice) has led to widespread disease persistence and pest resistance. Marine species biodiversity is rapidly declining due to overfishing, global warming, pathogens, and pollution. Thus, further biodiversity loss can change aquatic and terrestrial ecosystem functions and reduce ecosystem services. Food analysis results find the consumption of farmed salmon fillets contributes to higher rates of metabolic disorders, including diabetes and obesity. These farmed salmon also contain levels […]

Share

28
Apr

Glyphosate Breakdown Product Associated with Oxidative Stress and DNA Damage Among Children

(Beyond Pesticides, April 28, 2022) A study in Environmental Research finds that glyphosate’s primary metabolite (breakdown product), aminomethylphosphonic acid (AMPA), induces DNA damage through oxidative stress among subpopulations of primary school children. Although pyrethroid and chlorpyrifos metabolites can induce oxidative stress, this study is the first to investigate AMPA’s association with adverse health effects, rather than solely the effects of the active ingredient, glyphosate, in Roundup and other formulations. Glyphosate is the most commonly used active ingredient worldwide, appearing in many herbicide formulations, readily contaminating soil, water, food, and other resources. Chemical use has been increasing since the inception of crops genetically modified to tolerate glyphosate. However, studies demonstrate glyphosate is among the most prevalent pesticide contributors to human, biotic, and ecosystem harm. According to research, herbicide toxicity to invertebrates has doubled since 2004. Although research links glyphosate exposure to cancer, specifically non-Hodgkin lymphoma, much less research considers the effects that metabolites have on children who are more vulnerable to chemical exposure. Ecological and health risk assessments primarily focus on active ingredients in pesticide products, overlooking the potential impacts of metabolites. Thus, studies like these highlight the need to assess the implications of metabolite exposure to protect human, animal, and environmental health. The study notes, “Our […]

Share

20
Apr

Mother’s Exposure to Pesticides during Pregnancy Results in Sleep-Related Problems among Daughters

(Beyond Pesticides, April 20, 2022) A University of Michigan study is the first to highlight that maternal pesticide exposure during pregnancy adversely affects sleeping patterns for offspring later in life, specifically for females. Prenatal development is one of the most vulnerable periods of exposure as the fetus is most susceptible to the harmful effects of chemical contaminants. Many studies indicate that prenatal and early-life exposure to environmental toxicants increases susceptibility to diseases, from learning and developmental disabilities to cancer. However, the toxicity of pesticide exposure ad its full impact on the nonagricultural population in the U.S., especially women. Given research links to sleep-related disorders and neurological and cognitive development, studies like this can help government and health officials identify how pesticides’ impact on the brain elevates health concerns. The authors note, “Overall, these results are of public health importance considering the continued widespread agricultural and possibly residential use of pyrethroids and chlorpyrifos [in Mexico]…Thus, our results underline the importance of additional research studies that include both larger samples and assessment of unregulated pesticides, as well as studies that consider the underlying mechanisms explaining sex differences.” Levels of inadequate sleep patterns are rising among children and adolescents. Reports find variability in sleep duration results in higher rates of depression, anxiety, and […]

Share

15
Apr

Beyond Pesticides Makes Science-based Case that It Is Imperative to Phase Out Pesticides in a Decade

The organic solutions to problems highlighted in the latest issue of Pesticides and You—based on the importance of healthy ecosystems and public health protection—are within reach, and the data creates an imperative for action now that phases out pesticides within a decade, while ensuring food productivity, resilient land management, and safe food, air, and water. (Beyond Pesticides, April 15, 2022) The current issue of Pesticides and You, RETROSPECTIVE 2021: A Call to Urgent Action, is a look at a year of science, policy, and advocacy that informs both the existential problems that the U.S. and the world are facing due to toxic pesticide dependency, and solutions that can be adopted now. The information in this issue captures the body of science that empowers action at the local, state, and federal level, and provides a framework for challenging toxic pesticide use and putting alternatives in place. The issue finds that 2021 was a pivotal year in both defining the problem and advancing the solution. This year in review is divided into nine sections that provide an accounting of scientific findings documenting serious pesticide-induced health and environmental effects, disproportionate risk to people of color and those with preexisting conditions, regulatory failures, at the same time […]

Share

03
Dec

Degenerative Lung Diseases Associated with Atrazine Exposure, Worsened in Combination with Common Cancer Treatment

(Beyond Pesticides, December 2, 2021) A study published in Cellular Physiology and Biochemistry finds atrazine (ATR) exposure worsens lung disease outcomes in individuals with idiopathic (spontaneous) pulmonary fibrosis (IPF), a group of incurable lung diseases involving damaged/scarred lung tissue. Furthermore, chemotherapeutic products used to treat lymphoma (immune system cell cancer) like bleomycin can induce pulmonary fibrosis complications exacerbated by pesticide exposure. However, pesticide-related pulmonary fibrosis can have implications for neurological health, such as motor function. Scientific literature already finds an association between pesticide exposure and respiratory illnesses such as asthma, lung cancer, and chronic obstructive pulmonary disease (chronic bronchitis). Although IPF impacts over 5 million people a year globally, the disease is difficult to predict, which is concerning as the death rate is 50 to 56 percent within the first few years. Therefore, studies like this highlight the significance of evaluating how pesticide exposure impacts respiratory function, especially when exposure to respiratory toxicants increases vulnerability to existing respiratory-fixated illnesses like Covid-19. Advocate have urged the U.S. Environmental Protection (EPA) to incorporate scientific findings that these—where chemical exposures exacerbate an existing medical condition—into its pesticide registration review program. Researchers note, “[O]ur data represent an addition to the complex information on ATR-induced pulmonary toxicity. In particular, in this […]

Share

01
Dec

Banned Pesticides Associated with Endometriosis

(Beyond Pesticides, December 1, 2021) Women exposed to metabolites of the banned insecticide chlordane are over three times more likely to develop endometriosis, finds research published in the journal Environment International. The study is the latest to find links between persistent organic pollutants (POPs), still lingering in our environment and in our bodies, and chronic disease. According to an economic analysis conducted in 2016, exposure to endocrine (hormone) disrupting chemicals, often implicated in considerable damage to the body’s reproductive system, results in billions of dollars of health care costs from female reproductive disorders. Researchers set out to integrate two methodologies into their evaluation, combining analysis of POP biomarkers in blood with an analysis of biomarkers in that body that correspond with cell functioning, inflammation, and stress. A total of 87 women were enrolled in the study, half of whom had deep endometriosis, a quarter of whom also had the disease and sought surgical intervention, and a remaining quarter without reproductive concerns acted as a control. Twenty polychlorinated biphenyls (PCBs) and 30 organochlorine pesticide compounds were analyzed, as were various biomarkers and inflammatory cytokines. The analysis revealed two compounds to be positively associated with endometriosis – trans-nonachlor, a breakdown product of […]

Share

18
Nov

Pesticide Exposure Contributes to Preterm Births and Low Birth Weight

(Beyond Pesticides, November 18, 2021) A study published by King George’s Medical University, India, finds exposure to xenobiotic substances like pesticides during pregnancy increases risks associated with preterm birth, including a rise in cesarean section (C-section) deliveries and a decrease in fetal body weight. Preterm births occur when a fetus is born early or before 37 weeks of complete gestation. Premature births can result in chronic (long-term) illnesses among infants from lack of proper organ development and even death. Birth and reproductive complications are increasingly common among individuals exposed to environmental toxicants, like pesticides. The Center for Disease Control (CDC) reports the preterm birth rate is increasing annually. Therefore, studies like this can help government and health officials safeguard human health by assessing adverse effects following prevalent chemical exposure. The study notes, “To the best of our knowledge, this was a pioneering study, and it may help to increase our knowledge with regard to xenobiotic exposure in biological systems and the need for stringent guidelines for agricultural use of pesticides.” The study examines the association between the transfer of xenobiotics (foreign synthetic substances like pesticides) from mother to fetus. Transferal of these toxic substances can result in biological and chemical changes (i.e., genotoxicity […]

Share

21
Oct

Women in Agricultural Work at Increased Risk for Skin and Blood Cancers from Pesticide Exposure

(Beyond Pesticides, October 21, 2021) A study published in Environment International finds higher rates of various cancers among agricultural workers, with multiple myeloma (blood cancer) and melanoma (skin cancer) disproportionately impacting female farmers. Although research studies link cancer risk to genetic and external factors (e.g., cigarette smoke), there are increasing reports and scientific studies that pesticide exposure augments the risk of developing common cancers like melanoma and less common cancers like multiple myeloma. This study highlights the importance of understanding how pesticide use can increase the risk of latent diseases, which do not immediately develop upon initial exposure. The researchers note, “Given the large size of the agricultural population worldwide and the presence of various potential hazards in its working environment, such epidemiological data are important in improving occupational health measures and ensuring better workers’ health.” To investigate the cancer incidence patterns, researchers evaluated data from the AGRICOH database involving various international studies. The studies assessed pesticide exposure scenarios, which researchers use to determine the etiological (causal) agent of cancer incidences among farmers relative to the general population. Researchers analyzed data from eight different AGRICOH groups in various countries: France (AGRICAN), the U.S. (AHS, MESA), Norway (CNAP), Republic of Korea (KMCC), Denmark […]

Share

16
Sep

Persistent Organic Pollutants, including Banned Pesticides, Remain Present in all Fetal Organs Regardless of Maternal Chemical Contamination

(Beyond Pesticides, September 16, 2021) A study published in Chemosphere finds persistent organic pollutants (POPs), including organochlorine pesticides (OCPs), polychlorinated biphenyls (PCBs), and polybrominated diphenyl ethers (PBDEs), are present in the serum and placenta of pregnant mothers, as well as multiple fetal organs. Many studies indicate prenatal and early-life exposure to environmental toxicants increases susceptibility to diseases, from learning and developmental disabilities to cancer. However, this study is one of the first to demonstrate the presence of chemical toxicants in fetal tissue that are not present in maternal serum or placental samples. Prenatal development is one of the most vulnerable periods of exposure when the fetus is most susceptible to the harmful effects of chemical contaminants. Therefore, studies like these help government and health officials better identify fetal exposure contaminants and subsequent health concerns otherwise missed by current chemical monitoring methods. The researchers note, “These findings call for further evaluation of the current matrices used to estimate fetal exposure and establish a possible correction factor for a more accurate assessment of exposure in utero. We disclose the full data set on individual exposure concentrations to assist in building in silico models for prediction of human fetal exposure to chemicals.” Several studies associate early-life exposure to toxic chemicals […]

Share

10
Sep

More Scientific Evidence that Endocrine-Disrupting Pesticides Disrupt Thyroid Function

(Beyond Pesticides, September 10, 2021) Research conducted in Thailand shows that exposures to pesticides, even at low levels, can impact the human endocrine system and distort thyroid function. The study looked specifically at interactions of genetics and environment: it investigated associations between variations in genes involved in pesticide metabolism and altered thyroid hormone concentrations in agricultural workers. This research underscores some of the complexity and difficulty of determining human vulnerability to impacts of pesticide exposures, given genetic variables. Beyond Pesticides believes that this very complexity is a cogent argument for anchoring regulation of pesticides in the Precautionary Principle. If exposure to a pesticide can cause damage to human (or environmental) health, it sometimes will do so. Thus, to protect people’s health, agriculture and other land management practices must transition from the use of synthetic pesticides to broad adoption of organic regenerative approaches that obviate the need for such chemicals. This research is part of a longitudinal study that seeks to evaluate sub-chronic impacts, on thyroid hormone levels, of repeated exposures to a variety of pesticides. The farmworkers studied in this phase comprise two groups: those working on organically managed farms (216 subjects), and those working on conventional farms that use pesticides […]

Share

09
Sep

Endocrine (Hormone) Disrupting Chemicals, Including Pesticides, Also Affect the Nervous System

(Beyond Pesticides, September 9, 2021) A new study published in Toxicology Reports finds the same chemicals that disrupt the endocrine (hormone) system also disrupt the nervous system. Endocrine disruptors are xenobiotics (i.e., chemical substances like toxic pesticides foreign to an organism or ecosystem) present in nearly all organisms and ecosystems. The World Health Organization (WHO), European Union (EU), and endocrine disruptor expert (deceased) Theo Colborn, Ph.D., classify over 55 to 177 chemical compounds as endocrine disruptors, including various household products like detergents, disinfectants, plastics, and pesticides. Past research shows exposure to endocrine-disrupting pesticides adversely affects human health, from reproductive function to cancer development, and effects can span generations. However, this study is one of the few to evaluate associations between endocrine-disrupting chemicals and neurological function. Although the etiology (cause) of many sporadic (non-heritable) neurological diseases are unknown, scientists suggest exposure to environmental toxicants plays a role in disease development. Therefore, government and health officials have been urged to consider how exposure to endocrine-disrupting chemicals can impact bodily function and development apart from hormone disruption.   In the body, cells communicate through electrical or chemical signals transmitted within the nervous or endocrine system. Studies find exposure to endocrine-disrupting chemicals has a direct and indirect impact on hormone function and development. However, researchers investigated whether […]

Share

01
Sep

In Utero and Childhood Pesticide Exposure Increases Childhood Cancer Risk

(Beyond Pesticides, September 1, 2021) A study published in Environmental Pollution finds the risk of acute childhood leukemia (AL) increases with prenatal and newborn exposure to pesticides (i.e., insecticides and herbicides). The study results support the hypothesis that chronic environmental pesticide exposure increases childhood leukemia risk up to two times. Maternal exposure has a stronger association with leukemia than childhood exposure. Insecticides and herbicides are of particular significance in increasing leukemia risk, especially for acute lymphoblastic leukemia. Although medical advancements in disease survival are more prominent nowadays, childhood AL remains the secondary cause of child mortality following physical injury. Furthermore, childhood leukemia survivors can suffer from chronic or long-term health complications that may be life-threatening. Although the etiology or cause of childhood AL involves the interaction of multiple components like lifestyle and genetics, emerging evidence indicates that environmental contaminants like pesticides (e.g., occupational exposures, air pollution, pesticides, solvents, diet, etc.) play a role in disease etiology. Pesticide contamination is widespread in all ecosystems, and chemical compounds can accumulate in human tissues resulting in chronic health effects. Children are particularly vulnerable to the impacts of pesticide exposure as their developing bodies cannot adequately combat exposure effects. Already, studies find low levels of pesticide exposure during […]

Share

30
Aug

Tell EPA to Ban ALL Uses of Chlorpyrifos

(Beyond Pesticides, August 30, 2021) As with other actions on pesticides, EPA’s chlorpyrifos decision is filled with exceptions that respond to vested interests seeking to ignore or deflect the science. EPA, since announcing its decision in 1999 to ban “residential” uses of chlorpyrifos, continues to allow the following uses: (i) Residential use of containerized baits; (ii) Indoor areas where children will not be exposed, including only ship holds, railroad boxcars, industrial plants, manufacturing plants, or food processing plants; (iii) Outdoor areas where children will not be exposed, including only: golf courses, road medians, Industrial plant sites; (iv) Non-structural wood treatments including: fenceposts, utility poles, railroad ties, landscape timers, logs, pallets, wooden containers, poles, posts, and processed wood products; (v) Public health uses: Fire ant mounds (drench and granular treatment); (vi) nurseries and greenhouses; and (vii) Mosquito control. These uses are unaffected by EPA’s announcement. We need to finish the chlorpyrifos job. Tell EPA to ban all uses of chlorpyrifos. The collective effort to remove this one chemical is a tremendous feat in eliminating one exposure to a hazardous material for children. Achieving the ban on food uses required an enormously resource-intensive effort at a time in history when we are […]

Share

26
Aug

Exposure to Common Herbicide Glyphosate Increases Spontaneous Preterm Birth Incidents

(Beyond Pesticides, August 26, 2021) A recent study published in Environmental Research demonstrates that exposure to the herbicide glyphosate and its breakdown product reduces pregnancy length, increasing the risk of preterm birth. Preterm births occur when a fetus is born early or before 37 weeks of complete gestation. Premature births can result in chronic (long-term) illnesses among infants from lack of proper organ development and even death. Birth and reproductive complications are very common among individuals exposed to environmental toxicants, like pesticides. Considering the Center for Disease Control (CDC) reports the preterm birth rate is increasing annually, studies like this can help government and health officials safeguard human health by assessing adverse health effects following prevalent chemical exposure. The study notes, “Given the prevalent and rising exposures to glyphosate and GBHs [glyphosate-based herbicides], confirmatory studies are needed to explore reproductive effects of glyphosate and GBHs to re-assess their safety on human health and to explore possible programming consequences to lifelong health.” GBHs are the most commonly used herbicides, readily contaminating soil, water, and food globally. Although GBHs’ ubiquitous nature has been linked to carcinogenic effects, specifically non-Hodgkin lymphoma, much less research considers exposure effects on reproductive health. The study’s scientists aimed to examine the relationship […]

Share

16
Aug

Tell EPA: It Must Ban Pesticides Unless Shown Not To Be Endocrine Disruptors

(Beyond Pesticides, August 16, 2021) The failure of the U.S. Environmental Protection Agency (EPA) to meet its statutory responsibility to protect people and wildlife from the dire consequences of exposure to endocrine-disrupting chemicals must end. The Office of the Inspector General (OIG) for EPA has issued a damning report on the agency’s progress in protecting the population from potentially damaging endocrine disruption impacts of exposures to synthetic chemical pesticides (and other chemicals of concern) that shows the situation to be even worse than previously reported. The OIG’s summary statement says, “Without the required testing and an effective system of internal controls, the EPA cannot make measurable progress toward complying with statutory requirements or safeguarding human health and the environment against risks from endocrine-disrupting chemicals.” As a result, according to the OIG, “we have yet to see EPA use endocrine disruption findings in pesticide registration decisions.” Tell EPA that pesticide use cannot continue without findings of no endocrine disruption. Over recent decades, evidence has mounted showing that many pesticides interfere with hormones—and are therefore endocrine-disrupting chemicals (EDCs). In 1996, the promise of screening pesticides for endocrine disruption generated support from environmentalists and public health advocates for the Food Quality Protection Act […]

Share