Archive for the 'Endocrine Disruption' Category
18
Nov
(Beyond Pesticides, November 18, 2021) A study published by King George’s Medical University, India, finds exposure to xenobiotic substances like pesticides during pregnancy increases risks associated with preterm birth, including a rise in cesarean section (C-section) deliveries and a decrease in fetal body weight. Preterm births occur when a fetus is born early or before 37 weeks of complete gestation. Premature births can result in chronic (long-term) illnesses among infants from lack of proper organ development and even death. Birth and reproductive complications are increasingly common among individuals exposed to environmental toxicants, like pesticides. The Center for Disease Control (CDC) reports the preterm birth rate is increasing annually. Therefore, studies like this can help government and health officials safeguard human health by assessing adverse effects following prevalent chemical exposure. The study notes, “To the best of our knowledge, this was a pioneering study, and it may help to increase our knowledge with regard to xenobiotic exposure in biological systems and the need for stringent guidelines for agricultural use of pesticides.” The study examines the association between the transfer of xenobiotics (foreign synthetic substances like pesticides) from mother to fetus. Transferal of these toxic substances can result in biological and chemical changes (i.e., genotoxicity […]
Posted in Birth defects, Children, organochlorines, Women's Health | No Comments »
21
Oct
(Beyond Pesticides, October 21, 2021) A study published in Environment International finds higher rates of various cancers among agricultural workers, with multiple myeloma (blood cancer) and melanoma (skin cancer) disproportionately impacting female farmers. Although research studies link cancer risk to genetic and external factors (e.g., cigarette smoke), there are increasing reports and scientific studies that pesticide exposure augments the risk of developing common cancers like melanoma and less common cancers like multiple myeloma. This study highlights the importance of understanding how pesticide use can increase the risk of latent diseases, which do not immediately develop upon initial exposure. The researchers note, “Given the large size of the agricultural population worldwide and the presence of various potential hazards in its working environment, such epidemiological data are important in improving occupational health measures and ensuring better workers’ health.” To investigate the cancer incidence patterns, researchers evaluated data from the AGRICOH database involving various international studies. The studies assessed pesticide exposure scenarios, which researchers use to determine the etiological (causal) agent of cancer incidences among farmers relative to the general population. Researchers analyzed data from eight different AGRICOH groups in various countries: France (AGRICAN), the U.S. (AHS, MESA), Norway (CNAP), Republic of Korea (KMCC), Denmark […]
Posted in Cancer, Chemicals, Farmworkers, Multiple Myeloma, Women's Health | No Comments »
16
Sep
(Beyond Pesticides, September 16, 2021) A study published in Chemosphere finds persistent organic pollutants (POPs), including organochlorine pesticides (OCPs), polychlorinated biphenyls (PCBs), and polybrominated diphenyl ethers (PBDEs), are present in the serum and placenta of pregnant mothers, as well as multiple fetal organs. Many studies indicate prenatal and early-life exposure to environmental toxicants increases susceptibility to diseases, from learning and developmental disabilities to cancer. However, this study is one of the first to demonstrate the presence of chemical toxicants in fetal tissue that are not present in maternal serum or placental samples. Prenatal development is one of the most vulnerable periods of exposure when the fetus is most susceptible to the harmful effects of chemical contaminants. Therefore, studies like these help government and health officials better identify fetal exposure contaminants and subsequent health concerns otherwise missed by current chemical monitoring methods. The researchers note, “These findings call for further evaluation of the current matrices used to estimate fetal exposure and establish a possible correction factor for a more accurate assessment of exposure in utero. We disclose the full data set on individual exposure concentrations to assist in building in silico models for prediction of human fetal exposure to chemicals.” Several studies associate early-life exposure to toxic chemicals […]
Posted in Birth defects, Children, contamination, organochlorines, Women's Health | No Comments »
10
Sep
(Beyond Pesticides, September 10, 2021) Research conducted in Thailand shows that exposures to pesticides, even at low levels, can impact the human endocrine system and distort thyroid function. The study looked specifically at interactions of genetics and environment: it investigated associations between variations in genes involved in pesticide metabolism and altered thyroid hormone concentrations in agricultural workers. This research underscores some of the complexity and difficulty of determining human vulnerability to impacts of pesticide exposures, given genetic variables. Beyond Pesticides believes that this very complexity is a cogent argument for anchoring regulation of pesticides in the Precautionary Principle. If exposure to a pesticide can cause damage to human (or environmental) health, it sometimes will do so. Thus, to protect people’s health, agriculture and other land management practices must transition from the use of synthetic pesticides to broad adoption of organic regenerative approaches that obviate the need for such chemicals. This research is part of a longitudinal study that seeks to evaluate sub-chronic impacts, on thyroid hormone levels, of repeated exposures to a variety of pesticides. The farmworkers studied in this phase comprise two groups: those working on organically managed farms (216 subjects), and those working on conventional farms that use pesticides […]
Posted in 2,4-D, Agriculture, Carbaryl, Chlorpyrifos, cypermethrin, Endocrine Disruption, Environmental Protection Agency (EPA), Glyphosate, Lindane, Thyroid Disease, Uncategorized | No Comments »
09
Sep
(Beyond Pesticides, September 9, 2021) A new study published in Toxicology Reports finds the same chemicals that disrupt the endocrine (hormone) system also disrupt the nervous system. Endocrine disruptors are xenobiotics (i.e., chemical substances like toxic pesticides foreign to an organism or ecosystem) present in nearly all organisms and ecosystems. The World Health Organization (WHO), European Union (EU), and endocrine disruptor expert (deceased) Theo Colborn, Ph.D., classify over 55 to 177 chemical compounds as endocrine disruptors, including various household products like detergents, disinfectants, plastics, and pesticides. Past research shows exposure to endocrine-disrupting pesticides adversely affects human health, from reproductive function to cancer development, and effects can span generations. However, this study is one of the few to evaluate associations between endocrine-disrupting chemicals and neurological function. Although the etiology (cause) of many sporadic (non-heritable) neurological diseases are unknown, scientists suggest exposure to environmental toxicants plays a role in disease development. Therefore, government and health officials have been urged to consider how exposure to endocrine-disrupting chemicals can impact bodily function and development apart from hormone disruption.  In the body, cells communicate through electrical or chemical signals transmitted within the nervous or endocrine system. Studies find exposure to endocrine-disrupting chemicals has a direct and indirect impact on hormone function and development. However, researchers investigated whether […]
Posted in Alzheimers's, Amyotrophic Lateral Sclerosis (ALS), Autism, Endocrine Disruption, Nervous System Effects, Parkinson's | No Comments »
01
Sep
(Beyond Pesticides, September 1, 2021) A study published in Environmental Pollution finds the risk of acute childhood leukemia (AL) increases with prenatal and newborn exposure to pesticides (i.e., insecticides and herbicides). The study results support the hypothesis that chronic environmental pesticide exposure increases childhood leukemia risk up to two times. Maternal exposure has a stronger association with leukemia than childhood exposure. Insecticides and herbicides are of particular significance in increasing leukemia risk, especially for acute lymphoblastic leukemia. Although medical advancements in disease survival are more prominent nowadays, childhood AL remains the secondary cause of child mortality following physical injury. Furthermore, childhood leukemia survivors can suffer from chronic or long-term health complications that may be life-threatening. Although the etiology or cause of childhood AL involves the interaction of multiple components like lifestyle and genetics, emerging evidence indicates that environmental contaminants like pesticides (e.g., occupational exposures, air pollution, pesticides, solvents, diet, etc.) play a role in disease etiology. Pesticide contamination is widespread in all ecosystems, and chemical compounds can accumulate in human tissues resulting in chronic health effects. Children are particularly vulnerable to the impacts of pesticide exposure as their developing bodies cannot adequately combat exposure effects. Already, studies find low levels of pesticide exposure during […]
Posted in Birth defects, Children, Herbicides, Leukemia, Women's Health | No Comments »
30
Aug
(Beyond Pesticides, August 30, 2021) As with other actions on pesticides, EPA’s chlorpyrifos decision is filled with exceptions that respond to vested interests seeking to ignore or deflect the science. EPA, since announcing its decision in 1999 to ban “residential” uses of chlorpyrifos, continues to allow the following uses: (i) Residential use of containerized baits; (ii) Indoor areas where children will not be exposed, including only ship holds, railroad boxcars, industrial plants, manufacturing plants, or food processing plants; (iii) Outdoor areas where children will not be exposed, including only: golf courses, road medians, Industrial plant sites; (iv) Non-structural wood treatments including: fenceposts, utility poles, railroad ties, landscape timers, logs, pallets, wooden containers, poles, posts, and processed wood products; (v) Public health uses: Fire ant mounds (drench and granular treatment); (vi) nurseries and greenhouses; and (vii) Mosquito control. These uses are unaffected by EPA’s announcement. We need to finish the chlorpyrifos job. Tell EPA to ban all uses of chlorpyrifos. The collective effort to remove this one chemical is a tremendous feat in eliminating one exposure to a hazardous material for children. Achieving the ban on food uses required an enormously resource-intensive effort at a time in history when we are […]
Posted in Agriculture, Cancer, Children, Chlorpyrifos, Corteva, Dow Chemical, Endocrine Disruption, Environmental Protection Agency (EPA), Golf, Nervous System Effects, Rights-of-Way, Uncategorized, Wood Preservatives | No Comments »
26
Aug
(Beyond Pesticides, August 26, 2021) A recent study published in Environmental Research demonstrates that exposure to the herbicide glyphosate and its breakdown product reduces pregnancy length, increasing the risk of preterm birth. Preterm births occur when a fetus is born early or before 37 weeks of complete gestation. Premature births can result in chronic (long-term) illnesses among infants from lack of proper organ development and even death. Birth and reproductive complications are very common among individuals exposed to environmental toxicants, like pesticides. Considering the Center for Disease Control (CDC) reports the preterm birth rate is increasing annually, studies like this can help government and health officials safeguard human health by assessing adverse health effects following prevalent chemical exposure. The study notes, “Given the prevalent and rising exposures to glyphosate and GBHs [glyphosate-based herbicides], confirmatory studies are needed to explore reproductive effects of glyphosate and GBHs to re-assess their safety on human health and to explore possible programming consequences to lifelong health.” GBHs are the most commonly used herbicides, readily contaminating soil, water, and food globally. Although GBHs’ ubiquitous nature has been linked to carcinogenic effects, specifically non-Hodgkin lymphoma, much less research considers exposure effects on reproductive health. The study’s scientists aimed to examine the relationship […]
Posted in Birth defects, Children, Glyphosate, Reproductive Health | 1 Comment »
16
Aug
(Beyond Pesticides, August 16, 2021) The failure of the U.S. Environmental Protection Agency (EPA) to meet its statutory responsibility to protect people and wildlife from the dire consequences of exposure to endocrine-disrupting chemicals must end. The Office of the Inspector General (OIG) for EPA has issued a damning report on the agency’s progress in protecting the population from potentially damaging endocrine disruption impacts of exposures to synthetic chemical pesticides (and other chemicals of concern) that shows the situation to be even worse than previously reported. The OIG’s summary statement says, “Without the required testing and an effective system of internal controls, the EPA cannot make measurable progress toward complying with statutory requirements or safeguarding human health and the environment against risks from endocrine-disrupting chemicals.” As a result, according to the OIG, “we have yet to see EPA use endocrine disruption findings in pesticide registration decisions.” Tell EPA that pesticide use cannot continue without findings of no endocrine disruption. Over recent decades, evidence has mounted showing that many pesticides interfere with hormones—and are therefore endocrine-disrupting chemicals (EDCs). In 1996, the promise of screening pesticides for endocrine disruption generated support from environmentalists and public health advocates for the Food Quality Protection Act […]
Posted in Agriculture, Endocrine Disruption, Environmental Protection Agency (EPA), Take Action, Uncategorized | No Comments »
28
Jul
(Beyond Pesticides, July 29, 2021) New research published in Environmental Health Perspectives finds nearly 300 different chemicals in pesticides, consumer products, and contaminated resources (i.e., food, water) increase breast cancer risks. Breast cancer is the most common cancer among women, causing the second most cancer-related deaths in the United States. Past studies suggest genetic inheritance factors influence breast cancer occurrence. However, genetic factors only play a minor role in breast cancer incidences, while exposure to external environmental factors (i.e., chemical exposure) may play a more notable role. There are grave concerns over exposure to endocrine (hormone) disrupting chemicals and pollutants that produce adverse health effects. Most types of breast cancers are hormonally responsive and thus dependent on the synthesis of either estrogen or progesterone. Hormones generated by the endocrine system greatly influence breast cancer incidents among humans. Several studies and reports, including U.S. Environmental Protection Agency (EPA) data, identify hundreds of chemicals as influential factors associated with breast cancer risk. Therefore, advocates point to the need for national policies to reassess hazards associated with disease development and diagnosis upon exposure to chemical pollutants. The study’s researchers note, “This study shows that a number of chemicals currently in use have the ability to manipulate hormones known to adversely […]
Posted in Breast Cancer, contamination, Cyfluthrin, Reproductive Health | No Comments »
29
Jun
(Beyond Pesticides, June 29, 2021) Maine Governor Janet Mills (D) last week vetoed legislation prohibiting the aerial use of glyphosate and other dangerous herbicides in forestry practices. LD125, An Act To Prohibit the Aerial Spraying of Glyphosate and Other Synthetic Herbicides for the Purpose of Silviculture, was supported by a wide range of health and conservation groups, and aimed to bring the state in line with best practices for public health and the environment. With Maine recently passing one of the strongest consumer bans on pollinator-toxic neonicotinoids, advocates are dismayed by the setback from the Governor’s office. In a statement to Maine Public Radio, Senate President Troy Jackson said that Governor Mills should stop referring to herself as an environmentalist. “The science across the country, across the world, says that this stuff kills people, kills wildlife,” Mr. Jackson says. “And all that it is, is a giveaway to the large landowners so they can maximize their profits off the lives of the people in Maine and the wildlife in Maine.” Senator Jackson’s words are stern yet factual. Glyphosate has been identified by the World Health Organization as a probable human carcinogen. Monsanto, now owned by Bayer, has been the subject […]
Posted in Bayer, Cancer, Drift, Endocrine Disruption, Environmental Protection Agency (EPA), Forestry, Glyphosate, Maine, Monsanto, Pollinators, Uncategorized | No Comments »
28
Jun
(Beyond Pesticides, June 28, 2021) The endocrine disrupting herbicide propazine (in the triazine family of frog-deforming endocrine disruptors) is set for cancellation by the U.S. Environmental Protection Agency (EPA). The move would eliminate use of the hazardous herbicide by the end of 2022. However, all pesticides in the triazine class, including atrazine and simazine, have similar properties and should be eliminated from use. Tell EPA to finish the job by banning all triazines. In November 2020, Beyond Pesticides and allied environmental groups launched a lawsuit against EPA for its intent to reregister the triazine family of chemicals. The agency’s interim approval of the herbicides, conducted under the Trump administration, eliminates important safeguards for children’s health and a monitoring programs intended to protect groundwater from contamination. As is typical with EPA, the agency merely proposed minor label changes in attempts to mitigate risks identified in its registration review. According to a release from EPA, it made the decision not out of concerns relating to human health and environmental protection, but in order to provide “regulatory certainty” for farmers and local officials. In March 2021, the Biden administration requested a stay on the atrazine lawsuit brought by environmental groups, as it indicated […]
Posted in Atrazine, Endocrine Disruption, Environmental Protection Agency (EPA), Propazine, Reproductive Health, Take Action, Triazines, Uncategorized, Wildlife/Endangered Sp. | 3 Comments »
15
Jun
(Beyond Pesticides, June 15, 2021) The endocrine disrupting herbicide propazine (in the triazine family of frog-deforming endocrine disruptors) is set for cancellation by the U.S. Environmental Protection Agency (EPA), according to a Federal Register notice published last week. The move would eliminate use of the hazardous herbicide by the end of 2022. While health and environmental advocates are pleased with the agency’s move, they say it is critical that all pesticides in the triazine class, including atrazine and simazine, also be eliminated from use. In November 2020, Beyond Pesticides and allied environmental groups launched a lawsuit against EPA for its intent to reregister the triazine family of chemicals. The agency’s interim approval of the herbicides, conducted under the Trump administration, eliminates important safeguards for children’s health and a monitoring programs intended to protect groundwater from contamination. As is typical with EPA, the agency merely proposed minor label changes in attempts to avert risks identified in its registration review. According to a release from EPA, it made the decision not out of concerns relating to human health and environmental protection, but in order to provide “regulatory certainty” for farmers and local officials. In March 2021, the Biden administration requested a stay […]
Posted in Agriculture, Endocrine Disruption, Environmental Protection Agency (EPA), Propazine, Uncategorized | No Comments »
14
Jun
(Beyond Pesticides, June 14, 2021) Beyond Pesticides reports regularly on new science showing how pesticides harm human health and ecosystems. This science is not factored into EPA decisions. Tell EPA that cutting-edge science must be considered. More than 50 pesticide active ingredients have been identified as endocrine disruptors that mimic the action of a naturally-produced hormone, such as estrogen or testosterone, thereby setting off similar chemical reactions in the body; block hormone receptors in cells, thereby preventing the action of normal hormones; or affect the synthesis, transport, metabolism and excretion of hormones, thus altering the concentrations of natural hormones. Endocrine disruptors have been linked to attention deficit hyperactivity disorder (ADHD), Parkinson’s and Alzheimer’s diseases, diabetes, cardiovascular disease, obesity, early puberty, infertility and other reproductive disorders, childhood and adult cancers, and other metabolic disorders. Similar effects are found in other species. In spite of legal requirements and the flood of research, EPA issues Proposed Interim Decisions (PIDs) on pesticide registrations making no human health or environmental safety findings associated with the potential for endocrine disruption, or identifying additional data needs to satisfy Endocrine Disruptor Screening Program requirements in the PIDs. EPA cannot make findings of no unreasonable adverse effects without findings […]
Posted in ADHD, Alzheimers's, Endocrine Disruption, Environmental Protection Agency (EPA), Parkinson's, Reproductive Health, Toxic Waste, Uncategorized | No Comments »
10
Jun
(Beyond Pesticides, June 10, 2021) Exposure to toxic chemicals decreases egg count and increases infertility risk among women, according to a study published in Environment International. Since 2014, U.S. fertility rates have been decreasing, with many attributing the decline to older age pregnancies. However, several findings demonstrate that exposure to environmental pollutants, like persistent organic pollutants (POPs) from the industrial and agriculture industry, contributes to a decline in fertility rates. Scientists and health officials already associate exposure to POPs, like pesticides, with adverse impacts on male fertility, including reduced sperm count, quality, and abnormal sperm development. Therefore, it is essential to understand how exposure to toxic chemicals in the environment affects reproductive success, especially among women who can transfer contaminants to the fetus via the umbilical cord. The researchers note that these findings should urge government and health officials to reexamine chemical safety concerning reproductive health, and “strongly encourage [them] to study mechanisms behind POP-associated infertility in women in more detail.” Researchers examined ovarian egg reserve size in pregnant women directly by examining the density of follicles and immature eggs in ovarian tissue and indirectly via serum anti-MĂĽllerian hormone (AMH). Using AMH serum samples, researchers assessed concentration levels of 31 POPs: nine organochlorine pesticides (OCPs), ten polychlorinated […]
Posted in DDT, hexachlorobenzene (HCB), Infertility, organochlorines, PFAS, Reproductive Health, Women's Health | No Comments »
08
Jun
(Beyond Pesticides, June 8, 2021) Biosolid-based fertilizer products like Milorganite, often sold to consumers as “organic,” are contaminated with dangerous PFAS chemicals, according to a study published by Sierra Club and Ecology Center. Biosolids, also known as sewage sludge, have been found in the past to contain residues of hazardous pesticides, heavy metals, antibiotics and other pharmaceuticals, personal care products, and a range of other toxicants. While the latest news may not be surprising for careful shoppers who have long avoided biosolid fertilizers, none of these risks are relayed to consumers on fertilizer packages. With fertilizer regulations failing the American consumer, it becomes more important than ever to seek out certified organic fertilizer products. Sierra Club and Ecology Center looked at nine fertilizer products, each produced from the sewage sludge of a particular American city. For instance, Milorganite, perhaps the most well-known biosolid sludge fertilizer, is derived from the Milwaukee, Wisconsin sewage treatment system. Other products were derived from locations including Sacramento, CA (Synagro); Tacoma, WA (TAGRO); Madison, GA (Pro Care); Las Vegas, NV (Ecoscraps); Eau Claire, WI (Menards Premium Natural Fertilizer); Jacksonville, FL (Greenedge); North Andover, MA (Earthlife); and Washington, DC (Cured Bloom). As the report notes, many of […]
Posted in Asthma, Biosolids, Cancer, Developmental Disorders, Environmental Protection Agency (EPA), Fertilizer, PFAS, Reproductive Health, Sewage Sludge, Uncategorized, US Department of Agriculture (USDA) | No Comments »
25
May
(Beyond Pesticides, May 25, 2021) High levels of glyphosate in urine later in a pregnancy is significantly associated with preterm birth, according to recent research conducted by scientists at the University of Michigan. While awareness of the strong connection between glyphosate and certain cancers is growing among the public, the chemical’s link to adverse pregnancy outcomes is beginning to receive more attention. “Since most people are exposed to some level of glyphosate and may not even know it, if our results reflect true associations, then the public health implications could be enormous,” said senior author John Meeker, ScD, professor at the University of Michigan School of Public Health. This latest study is part of a cohort dubbed PROTECT (Puerto Rico Testsite for Exploring Contamination Threats), focused on investigating environmental exposures leading to preterm birth in Puerto Rico. Previous research indicates that Puerto Rico has some of the highest rates of preterm births in the United States, roughly matching Mississippi. With America’s abysmal track record for maternal care, preterm birth rates in these locations also represent the highest in the world. In order to determine the association between glyphosate use and preterm pregnancy, pregnant women between the ages of 18 to […]
Posted in Bayer, Environmental Protection Agency (EPA), Glyphosate, Monsanto, Reproductive Health, Uncategorized | No Comments »
06
May
(Beyond Pesticides, May 6, 2021) Nearly half of all breakdown products (transformation products) from four common-use environmental pesticides produce stronger endocrine (hormone) disrupting (ED) effects than the parent compound, according to new research published in Environment International. Over 300 environmental contaminants and their byproducts—from chemicals in plastics to cosmetic/personal care products—are commonly present in water bodies, food commodities, and human blood/urine samples. These toxicants can alter hormone metabolism, producing endocrine-disrupting effects that put the health of animals, humans, and the environment at risk. Many ecological and health risk assessments for pesticides focus on the effects of parent chemical compound products, overlooking the potential impacts of transformation products (TPs). Therefore, studies like these highlight the need to assess the implications of TPs to safeguard human, animal, and environmental health. The researchers note, “Since an increasing number of pesticide TPs have been detected in various environmental media, a more comprehensive understanding of the ecological risk of pesticide TPs is imperative for risk assessments more extensively and regulatory policy-making on pesticide restriction in the future.” Endocrine disruptors are xenobiotics (i.e., chemical substances like toxic pesticides foreign to an organism or ecosystem), including pesticides, bisphenols, phthalates, persistent organic pollutants (POPs), and heavy metals. Past research demonstrates exposure […]
Posted in Chemicals, contamination, Endocrine Disruption, Metabolites | No Comments »
29
Apr
(Beyond Pesticides, April 29, 2021) Glyphosate-based herbicides (GBHs) are incompatible with sustainable agriculture goals, according to a recent scientific literature analysis by scientists at Tufts University, Massachusetts. Glyphosate is the most commonly used pesticide active ingredient worldwide, appearing in many herbicide formulas, including Bayer’s (formerly Monsanto) RoundupTM. The use of this chemical has been increasing since the inception of crops genetically modified to tolerate glyphosate. However, studies demonstrate glyphosate is the main contributor to human, biotic, and ecosystem harms as toxicities from herbicides are now double what it was in 2004. The National Academy of Sciences identifies four goals of sustainable agriculture—productivity, economics, environment, and social well-being for future generations. However, pesticides like glyphosate are ubiquitous in the environment, putting the health, economy, and food/resources for future generations at risk. Therefore, research like this is vital for understanding how chemical use can undermine sustainable agriculture goals to protect humans, animals, and environmental health. Researchers note, “[W]hether or not GBHs are viewed as essential or unessential to contemporary agriculture, and notwithstanding their role in non-tillage agriculture, this study shows that glyphosate-based herbicides do not reach the bar of agricultural sustainability, with respect to humans and the environment, making the system they are part of unsustainable.” Researchers thoroughly examined […]
Posted in Agriculture, Alternatives/Organics, Antibiotic Resistance, Antimicrobial, Birth defects, Brain Effects, Cancer, Disease/Health Effects, Glyphosate, Herbicides, Microbiata, Microbiome, Oxidative Stress, Pollinators, Resistance, Wildlife/Endangered Sp. | No Comments »
22
Apr
(Beyond Pesticides, April 22, 2021) Past maternal exposure to the pesticide dichlorodiphenyltrichloroethane (DDT) during pregnancy can increase the risk of breast cancer and cardiometabolic disorders (e.g., heart disease, obesity, diabetes) up to three successive generations, according to a new study published in Cancer Epidemiology, Biomarkers & Prevention. Although previous studies highlight early life or in utero exposure to DDT increasing breast cancer risk later in life, this study is the first to note generational effects on grandchildren’s health. DDT continues to adversely affect the health of the U.S. population, nearly 50 years after its ban. However, this ban is not global, as many countries still use or manufacture the chemical compound. Furthermore, residues of DDT metabolite, DDE, continue to readily contaminate food and water worldwide. Therefore, studies like these highlight the need to investigate how first-generation pesticide exposure can impact future generational health in order to prevent adverse health outcomes, especially during sensitive developmental periods (i.e., in utero, infancy/childhood). The study researchers note, “Discovery of actionable biomarkers of response to ancestral environmental exposures in young women may provide opportunities for breast cancer prevention.” To assess the association between multi-generational health risks and chemical exposure, researchers used the Public Health Institute’s Child […]
Posted in Biomonitoring, Breast Cancer, Children, contamination, DDT, Epigenetic, multi-generational effects, Pesticide Residues, Women's Health | No Comments »
15
Apr
(Beyond Pesticides, April 15, 2021) Gestational (during pregnancy) and childhood exposure to per- and polyfluoroalkyl substances (PFAS) increase cardiometabolic risk, or the risk of heart diseases and metabolic disorders, later in life, according to a Brown University study published in Environment International. Past studies associate exposure to chemical pollutants with increased susceptibility to adverse health effects during critical fetal and childhood developmental periods. Some of these health effects are cardiometabolic risk factors, including obesity, insulin issues, abnormal blood pressure, that increase the risk of developing cardiovascular disease (CVD) and metabolic disorders (e.g., type 2 diabetes). PFAS are of particular concern as these endocrine-disrupting chemicals are common in non-stick cookware, cleaning/personal care products, food packaging, and other consumer products. They are now being found in pesticide products. Because of their ubiquitous use in many products, studies report that PFAS compounds are detectable in infants, children, and pregnant women. Furthermore, pregnant women can readily transfer compounds to the developing fetus through the placenta. Cardiovascular disease and diabetes are among the leading causes of death globally. Additionally, heart conditions are one leading cause of disability in the U.S., as research demonstrates environmental pollutant exposure can increase the risk of developing cardiovascular disease, including stroke, heart attack, heart failure, atrial fibrillation, and cardiac […]
Posted in Cardiovascular Disease, Children, Diabetes, Obesity, PFAS, Uncategorized, Women's Health | No Comments »
05
Apr
(Beyond Pesticides, April 5, 2021) The failure of EPA to meet its statutory responsibility to protect people and wildlife from the dire consequences of exposure to endocrine disrupting chemicals must end. Over recent decades, evidence has mounted showing that many pesticides interfere with hormones—and are therefore endocrine-disrupting chemicals (EDCs). In 1996, the promise of screening pesticides for endocrine disruption generated support from environmentalists and public health advocates for the Food Quality Protection Act (FQPA), which traded the absolute prohibition of carcinogens in food of the Delaney Clause for a risk assessment standard that is subject to manipulation and an underestimation of real-life hazards. And now, 25 years later, we have yet to see EPA use endocrine disruption findings in pesticide registration decisions. >>Tell EPA that pesticide use cannot continue without findings of no endocrine disruption. The endocrine system consists of a set of glands (thyroid, gonads, adrenal and pituitary) and the hormones they produce (thyroxine, estrogen, testosterone and adrenaline), which help guide the development, growth, reproduction, and behavior of animals, including humans. Hormones are signaling molecules, which travel through the bloodstream and elicit responses in other parts of the body. More than 50 pesticide active ingredients have been identified as […]
Posted in Agriculture, Endocrine Disruption, Environmental Protection Agency (EPA), Take Action, Uncategorized, Wildlife/Endangered Sp. | No Comments »
25
Mar
(Beyond Pesticides, March 25, 2021) A new University of California San Francisco (UCSF) study, published in Environmental Science & Technology, finds over 100 chemicals present in U.S. pregnant women’s blood and umbilical cord samples. This discovery ignites concerns over prenatal exposure to chemicals from consumer and industrial products and sources. Furthermore, 89 percent of these chemical contaminants are unknown sources and uses, lacking adequate information, or are not previously detectable in humans. The National Health and Nutrition Examination Survey (NHANES) finds U.S. pregnant women experience frequent exposure to environmental pollutants that pose serious health risks to both mother and newborn. Many known environmental pollutants (i.e., heavy metals, polychlorinated biphenyl, and pesticides) are chemicals that can move from the mother to the developing fetus at higher exposure rates. Hence, prenatal exposure to these chemicals may increase the prevalence of birth-related health consequences like natal abnormalities and learning/developmental disabilities. Current chemical biomonitoring methods only analyze a targeted few hundred chemicals—a small portion of the over 8000 chemicals the U.S. manufactures and imports. However, this study employs new technology that identifies a more comprehensive range of industrial chemicals. Therefore, research like this is essential for future technological development that can identify likely omnipresent chemical exposures for future health risks. UCSF scientists […]
Posted in Biomonitoring, Birth defects, Cancer, Chemicals, Children, contamination, Developmental Disorders, Disease/Health Effects, Reproductive Health, Women's Health | No Comments »