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Breakdown Products (Metabolites) from Pesticides May Be More Toxic than Parent Compound, Study Finds

Thursday, May 6th, 2021

(Beyond Pesticides, May 6, 2021) Nearly half of all breakdown products (transformation products) from four common-use environmental pesticides produce stronger endocrine (hormone) disrupting (ED) effects than the parent compound, according to new research published in Environment International. Over 300 environmental contaminants and their byproducts—from chemicals in plastics to cosmetic/personal care products—are commonly present in water bodies, food commodities, and human blood/urine samples. These toxicants can alter hormone metabolism, producing endocrine-disrupting effects that put the health of animals, humans, and the environment at risk. Many ecological and health risk assessments for pesticides focus on the effects of parent chemical compound products, overlooking the potential impacts of transformation products (TPs). Therefore, studies like these highlight the need to assess the implications of TPs to safeguard human, animal, and environmental health. The researchers note, “Since an increasing number of pesticide TPs have been detected in various environmental media, a more comprehensive understanding of the ecological risk of pesticide TPs is imperative for risk assessments more extensively and regulatory policy-making on pesticide restriction in the future.” Endocrine disruptors are xenobiotics (i.e., chemical substances like toxic pesticides foreign to an organism or ecosystem), including pesticides, bisphenols, phthalates, persistent organic pollutants (POPs), and heavy metals. Past research demonstrates exposure […]

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Grandmother’s Exposure to DDT Increases Granddaughters’ Breast Cancer and Cardiometabolic Disorder Risk

Thursday, April 22nd, 2021

(Beyond Pesticides, April 22, 2021) Past maternal exposure to the pesticide dichlorodiphenyltrichloroethane (DDT) during pregnancy can increase the risk of breast cancer and cardiometabolic disorders (e.g., heart disease, obesity, diabetes) up to three successive generations, according to a new study published in Cancer Epidemiology, Biomarkers & Prevention. Although previous studies highlight early life or in utero exposure to DDT increasing breast cancer risk later in life, this study is the first to note generational effects on grandchildren’s health. DDT continues to adversely affect the health of the U.S. population, nearly 50 years after its ban. However, this ban is not global, as many countries still use or manufacture the chemical compound. Furthermore, residues of DDT metabolite, DDE, continue to readily contaminate food and water worldwide. Therefore, studies like these highlight the need to investigate how first-generation pesticide exposure can impact future generational health in order to prevent adverse health outcomes, especially during sensitive developmental periods (i.e., in utero, infancy/childhood). The study researchers note, “Discovery of actionable biomarkers of response to ancestral environmental exposures in young women may provide opportunities for breast cancer prevention.” To assess the association between multi-generational health risks and chemical exposure, researchers used the Public Health Institute’s Child […]

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Study Finds Eagle Populations Experiencing Widespread Rodenticide Exposure

Wednesday, April 21st, 2021

(Beyond Pesticides, April 21, 2021) The vast majority of bald and golden eagles in the United States are contaminated with toxic anticoagulant rodenticides, according to research published in the journal PLOS One earlier this month. Although eagle populations have largely recovered from their lows in the 1960s and 70s, the study is a stark reminder that human activity continues to threaten these iconic species. “Although the exact pathways of exposure remain unclear, eagles are likely exposed through their predatory and scavenging activities,” said study author Mark Ruder, PhD, assistant professor at the University of Georgia to CNN. Eagle carcasses were retrieved from the University of Georgia’s ongoing Southeastern Cooperative Wildlife Disease Study. Eighteen state wildlife agencies and the U.S. Fish and Wildlife Service all sent in specimens from a period spanning 2014 to 2018. In total, 116 bald eagle and 17 golden eagle carcasses had their livers tested for the presence of anticoagulant rodenticides. Out of the 116 bald eagles tested, 96, or 83% had were exposed to toxic rodenticides. Forty of the eagles  (35%) were exposed to more than one rodenticide compound. Thirteen out of 17 golden eagles were contaminated was rodenticides, with four exposed to a single rodenticide […]

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Pesticides Are More Widespread in Both Conventional and Organic Agricultural Soils than Previously Thought

Thursday, April 1st, 2021

(Beyond Pesticides, April 1, 2021) A legacy of toxic pesticide use in agriculture is showing up as residues on organic farms, emphasizing the threat of a history of weak regulatory standards that has left farmland poisoned and the urgent need to transition to organic. A study, published in Environmental Science & Technology, documents the findings of pesticide residues on organic farmland and shows a decrease in residues after transition, with lingering effects for decades.  Some banned pesticides like organochlorines (e.g., DDT and chlordecone) are stable as research demonstrates these chemicals can bind to and linger in the dirt for years to decades. However, other current-use pesticides also pose a soil contamination risk due to drift, runoff, and leaching.  Widespread, increasing pesticide use in genetically engineered crops has implications for contamination of natural resources, including soils. Since pesticide residues can kill off beneficial soil life, impacting soil health and function, agricultural production may decline. Past studies examining pesticide residues rarely investigate residue’s presence in the soil where the chemical has never been used, like organic systems. Therefore, studies like these highlight the need to examine the effect potential pesticide contamination has on soil health, especially in organic where reliance on biological soil […]

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Over 100 Chemicals Detectable in Pregnant Women, Including 98 “New” or Unknown Compounds

Thursday, March 25th, 2021

(Beyond Pesticides, March 25, 2021) A new University of California San Francisco (UCSF) study, published in Environmental Science & Technology, finds over 100 chemicals present in U.S. pregnant women’s blood and umbilical cord samples. This discovery ignites concerns over prenatal exposure to chemicals from consumer and industrial products and sources. Furthermore, 89 percent of these chemical contaminants are unknown sources and uses, lacking adequate information, or are not previously detectable in humans. The National Health and Nutrition Examination Survey (NHANES) finds U.S. pregnant women experience frequent exposure to environmental pollutants that pose serious health risks to both mother and newborn. Many known environmental pollutants (i.e., heavy metals, polychlorinated biphenyl, and pesticides) are chemicals that can move from the mother to the developing fetus at higher exposure rates. Hence, prenatal exposure to these chemicals may increase the prevalence of birth-related health consequences like natal abnormalities and learning/developmental disabilities.  Current chemical biomonitoring methods only analyze a targeted few hundred chemicals—a small portion of the over 8000 chemicals the U.S. manufactures and imports. However, this study employs new technology that identifies a more comprehensive range of industrial chemicals. Therefore, research like this is essential for future technological development that can identify likely omnipresent chemical exposures for future health risks. UCSF scientists […]

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Ecosystem Health: Pesticide Use from Forest Management Practices Threatens Essential West Coast Marine Organisms

Thursday, March 11th, 2021

(Beyond Pesticides, March 11, 2021) A Portland State University (PSU) study finds that pesticides from the forestry industry threaten clams, mussels, oysters (bivalves) along the Oregon state coast. Bivalves are excellent indicator species, signaling environmental contamination through their sedimentary, filter-feeding diet. However, continuous pesticide inputs—from various forestry management regimes—into watersheds along Oregon’s coastal zone endanger these species in downstream rivers and estuaries (river mouths). Although research demonstrates many forestry practices (e.g.., road building, planting, clearcutting, thinning) have cumulative effects on the ecosystem, there is a lack of studies addressing the overall impact of multiple chemical mixtures and application on watersheds and subsequent aquatic transport. Like agriculture, conventional forest management across the U.S. depends on the use of toxic pesticides to control pest populations. However, pesticide residues from application drift, runoff, and contamination continuously jeopardize the health and fitness of various non-target species, including humans. Marine ecosystem pollution is difficult to track and measure, and forestry pesticide regulations can invoke variations in water quality requirements through discrepancies in buffer zones and application concentrations. Therefore, studies like this can help guide future forest management practices to reduce the number of chemicals entering aquatic ecosystems. Researchers in the study note, “These findings highlight the need to […]

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Implications for Human Health: Glyphosate-Related Soil Erosion Re-Releases Toxic Pesticides from Soil

Thursday, March 4th, 2021

(Beyond Pesticides, March 4, 2021) A new study finds glyphosate use stimulates soil erosion responsible for releasing banned, toxic pesticide chlordecone (Kepone), which was used in banana production. For years, an unknown pollution source continuously contaminated water surrounding islands in the French West Indies (Martinique and Guadeloupe). However, researchers from the University of Savoie Mont Blanc in France have found that chlordecone—extensively used on banana farms from 1972 to 1993—is the contamination culprit. Glyphosate is the most popular herbicide in the world, thus ubiquitous in the environment. Therefore, it is vital to understand the implication glyphosate use has on soil health and the potential re-release of soil-bound, toxic contaminants into the surrounding environment to safeguard human health. Researchers note, “[Chlordecone] fluxes drastically increased when glyphosate use began, leading to widespread ecosystem contamination. As glyphosate is used globally, ecotoxicological risk management strategies should consider how its application affects persistent pesticide storage in soils, transfer dynamics, and widespread contamination.” Conventional pesticide use contaminates soil and their respective Critical Zone (CZ) compartments. These CZ compartments interact between the four main spheres (i.e., hydrosphere, biosphere, lithosphere, and atmosphere) of the Earth to support life. Recent decades demonstrate an increase in soil erosion due to sediment changes […]

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Aggressive Cancer in Sea Lions Linked to Ocean Pollution and Herpesvirus Precursor, Implications for Human Health

Thursday, February 11th, 2021

(Beyond Pesticides, February 11, 2021) California sea lions (Zalophus californianus) are experiencing high rates of urogenital carcinoma (UGC) cancer incidences from the combined effect of toxic “legacy” pesticides like DDT and the viral infection Otarine herpesvirus-1 (OtHV1), according to a new study published in Frontiers in Marine Science. Previous research documents the role herpesvirus infection, genotype, and organochlorine pesticides play in sea lion cancer development. However, synergism (collaboration) between viral infection and toxic chemical exposure increases cancer development odds. Pollution of the oceans with toxic chemicals lacks adequate regulation, is widespread and only getting worse. More than 80 percent of ocean pollution comes from land-based, anthropological activities. A recent study published in Annals of Public Health finds toxic chemicals from pesticides, heavy metals, plastics, and other sources readily contaminate the ocean, especially near coastal regions where chemical inputs occur in higher concentrations. Globally, pollution has major disease implications, causing the deaths of over nine million people annually. Therefore, it is essential to understand the co-effects of ocean pollution and diseases to protect human health. Authors of the study state, “This study has implications for human health, as virally associated cancer occurs in humans, and likelihood of cancer development could similarly be increased by exposure to environmental […]

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Persistent Organic Pollutants like Organochlorine Pesticides Pose Health Risk to Rare Giant Panda Subspecies

Thursday, January 28th, 2021

(Beyond Pesticides, January 28, 2021) Persistent organic pollutants (POPs)—including banned pesticides—present a health risk to the endangered Qinling Panda (Ailuropoda melanoleuca qinlingensis), the rarest subspecies of giant pandas, according to a new Chinese study published in Environmental Pollution. Organochlorine compounds (OCs), such as organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs), are well-known persistent organic pollutants. They were banned by the Stockholm Convention treaty in 2001 and are primary pollutants of concern (UNEP, 2009) because of their persistence, toxicity, and adverse effects on environmental and biological health. These pollutants have a global distribution, with evaporation and precipitation facilitating long-range atmospheric transport, deposition, and bioaccumulation of hazardous chemicals in the environment. The U.S. was a signatory to the treaty, but U.S. Senate never ratified it, relegating U.S. officials to observer status. Although various studies demonstrate the volatile, toxic nature of POPs, much less research evaluates the impact POPs have on biodiversity over time. The globe is currently going through the Holocene Extinction, Earth’s 6th mass extinction, with one million species of plants and animals at risk. With the increasing rate of biodiversity loss, advocates say it is essential for government agencies to research how previous and ongoing use of POPs can impact present-day species. Likewise, collaborative, […]

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Stop EPA from Limiting State Pesticide Restrictions as Corporate Deception on Hazards Continues

Monday, December 21st, 2020

(Beyond Pesticides, December 21, 2020) The toxic herbicide dicamba is once again at the center of a larger story about states’ authority to regulate pesticides more stringently federal dictates and a response to corporate corruption in the marketing of pesticide products. The Trump EPA (U.S. Environmental Protection Agency) has just made it much harder for state regulations to be more protective than federal rules. It did so via a footnote embedded in dozens of pages of regulatory documents related to EPA’s registration of three new dicamba products.  Tell the Biden transition team that EPA must respect states’ rights to protect people and property in their states. Meanwhile, a report by the Midwest Center for Investigative Reporting found Monsanto and BASF, a German chemical company that worked with Monsanto to launch the system coupling dicamba with resistant crops, knew their dicamba herbicides would cause large-scale damage to fields across the U.S., but decided to push them on unsuspecting farmers anyway, in a bid to corner the soybean and cotton markets with their dicamba-resistant seeds. For nearly 30 years, state regulators have used Section 24 (“Special Local Needs” section) of FIFRA, the Federal, Insecticide, Fungicide and Rodenticide Act—the law that gives EPA […]

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Food For Thought: Eating Organic Reduces Risk of Type 2 Diabetes

Tuesday, November 24th, 2020

(Beyond Pesticides, November 24, 2020) Reinforcing a body of scientific evidence, a new study finds that eating organic food lowers one’s risk of developing type 2 diabetes. With 1 in 10 (34 million) Americans afflicted with type 2 diabetes, and 1 in 3 (88 million) with prediabetes, new strategies focused on prevention are urgently needed. The results of the study, published by a team of French and American researchers in the International Journal of Behavioral Nutrition and Physical Activity, reinforce the triple bottom line (profit, people, and the environment) benefits of organic food for public health, the environment, and the wider economy. Scientists used data from NutriNet-SantĂ©, a massive study including over 170,000 participants (averaging 52 years old) that regularly respond to questions concerning lifestyle, dietary intake, body type, physical activity, and health status. Roughly 33,000 NutriNet-SantĂ© participants completed food frequency questionnaire regarding how often they consumed organic food. After four years, 293 surveyed individuals had been diagnosed with type 2 diabetes. Researchers then looked at how organic food consumption affected the risk of developing the disease, adjusting for body mass index, gender, family history of diabetes, physical activity, education, economic status, occupation, smoking, and alcohol consumption. Higher organic food […]

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Parents Sue Manufacturer of Neurotoxic Insecticide Chlorpyrifos, Corteva (formerly Dow), for Causing Child’s Disabilities

Friday, October 23rd, 2020

(Beyond Pesticides, October 23, 2020) In central California, what promises to be a landmark series of lawsuits against Corteva (formerly DowAgroSciences), maker of the pesticide chlorpyrifos, is under way, spearheaded by the case Alba Luz Calderon de Cerda and Rafael Cerda Martinez v. Corteva Inc., et al. This first suit, brought by the parents of Rafael Cerda Calderon, Jr. on his behalf, charges that his lifelong disabilities were caused by chronic exposures to chlorpyrifos. The parents are suing for general damages, compensatory damages (due to Rafael, Jr.’s loss of earning capacity), medical care costs, and “punitive damages for the willful, reckless, and recklessly indifferent conduct of the Defendants” in intentionally hiding the dangers of their chlorpyrifos products from customers and the public. As with so many dangerous pesticides, absent effective federal regulation, states, cities, and other entities are taking action to protect people from this compound, and as in this case, individuals are seeking redress for harms suffered. Beyond Pesticides has long advocated for a ban on the use of chlorpyrifos because of the grave risks it poses. The case was filed in mid-September in California Superior Court, Kings County, and names not only Corteva, but also, the cities of Huron and Avenal, Woolf […]

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Primates, Both Wild and Captive, Are Being Exposed to Toxic Pesticides and Flame Retardants

Tuesday, September 15th, 2020

(Beyond Pesticides, September 15, 2020) Both wild and captive primates are being exposed to hazardous pesticides and flame retardants, according to research published this month in the journal Environmental Science and Technology. This is the first study to look at the threat anthropogenic (man-made) chemicals may present for this important order of animals. “We think a lot about habitat disturbance, logging, and hunting as threats to these species, while pollution has been overlooked,” study co-author Michael Wasserman, told Environmental Health News (EHN). Scientists conducted their research by first obtaining fecal samples from three distinct primate populations: captive baboons from an Indiana zoo, wild howler monkeys from a research station in Costa Rica, and wild chimpanzees, red-tailed monkeys, and red colobus monkeys from a Ugandan national park. Samples were then tested for a range of chemicals, including 50 pesticides, and nearly 70 flame retardants. Scientists discovered legacy pesticides (such as heptachlor, DDT, hexachlorohexane, chlordane, and related compounds) in every species tested, with the highest levels found in red colobus and red-tailed monkeys. In particular, DDT and its related compounds (DDD and DDE) were found to be widespread, with red colobus monkeys registering a median of 260 ppb DDE in its waste. […]

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Arctic Glaciers Entrap Pesticides and Other Environmental Pollutants from Global Drift and Release Hazardous Chemicals as They Melt from Global Warming

Thursday, August 20th, 2020

(Beyond Pesticides, August 20, 2020) Persistent organic pollutants (POPs), including banned and current-use pesticides are present in snow and ice on top of Arctic glaciers, according to the study, “Atmospheric Deposition of Organochlorine Pesticides and Industrial Compounds to Seasonal Surface Snow at Four Glacier Sites on Svalbard, 2013–2014,” published in Environmental Science & Technology. Past research finds that air contaminated with these environmentally bioaccumulative, toxic chemicals drift toward the poles, becoming entrapped in ice under the accumulating snowfall. As the global climate continues to rise and the climate crisis worsens, studies like this become significant, as glaciers encapsulating these toxic chemicals are melting. Upon melting, some chemicals can volatize back into the atmosphere releasing toxicants into air and aquatic systems, with the ensuing consequences. Although this research demonstrates that specific computer programs can track the trajectory of chemically contaminated air parcels with practical precision, it falls to global leaders to curtail the continued manufacturing of these chemical pollutants. [For related pieces, see Silent Snow: The unimaginable impact of toxic chemical use and DDT in Glacial Melt Puts Alaskan Communities at Risk.] Countless scientists consider Arctic environments to be “pristine,” void of direct chemical inputs from pesticides and other POPs. However, the Arctic has become a sink for […]

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28 Pesticides Linked to Mammary Gland Cancer, Inadequately Reviewed by EPA

Friday, August 7th, 2020

(Beyond Pesticides, August 7, 2020) Research out of the Silent Spring Institute identifies 28 registered pesticides linked with development of mammary gland tumors in animal studies. Study authors Bethsaida Cardona and Ruthann Rudel also report that many of the pesticides they investigated behave as endocrine disruptors; breast cancers in humans are significantly influenced by hormones generated by the endocrine system. The Environmental Protection Agency (EPA) acknowledges that nine of these 28 pesticide compounds cause mammary tumors, but dismisses the evidence of the other 19. The results of this research, published in the journal Molecular and Cellular Endocrinology, evince Beyond Pesticides’ long-standing argument that the risk assessment process used by EPA for its pesticide registration process is substantially inadequate to protect human health. The co-authors cite, as the catalyst for this research project, a Cape Cod resident’s outreach to the Silent Spring Institute several years ago, asking for information about the herbicide triclopyr because utility companies wanted to spray it on vegetation below local power lines. (The compound has also been used by the logging industry in the Pacific Northwest.) They reviewed more than 400 EPA pesticide documents on the health impacts of many registered pesticides for this research, conducted as part […]

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Pesticide Use Linked to Increased Risk of Lung Cancer

Thursday, July 23rd, 2020

(Beyond Pesticides, July 23, 2020) Chronic pesticide use, and subsequent exposure, elevate a person’s risk of developing lung cancer, according to a study published in F1000Research by researchers at the Nakhon Sawan Provincial Public Health Office and Naresuan University, Thailand. Globally, cancer is one of the leading causes of death, with over 8 million people succumbing to the disease every year. Notably, the International Agency for Cancer Research (IARC) predicts new cancer cases to rise 67.4% by 2030. Although there is a vast amalgamation of research linking cancer risk to genetic and external factors (i.e., cigarette smoke), there is increasing evidence that pesticide exposure augments the risk of developing lung cancer, as well. This study highlights the importance of understanding how pesticide use can increase the risk of latent diseases, which do not readily develop upon initial exposure.  Study researchers state, “To our knowledge, the association between lung cancer and pesticides has never been studied before among [Thai] people. The objective of this study was to investigate associations between pesticide exposure and lung cancer among people [living in Nakhon Sawan province, Thailand]. The results can be used for the prevention of lung cancer, and to support the global literature.” Lung cancer is one of the […]

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Take Action: Tell Public Officials to Stop Mosquito Spraying and Adopt a Safe, Effective Mosquito Management Plan

Monday, July 20th, 2020

(Beyond Pesticides, July 20, 2020) Does your community spray toxic pesticides for mosquitoes? In a well-intentioned but ill-informed attempt to prevent mosquito-borne illness such as West Nile virus, many communities spray insecticides (adulticides) designed to kill flying mosquitoes. If your community is one of these, then your public officials need to know that there is a better, more-effective, way to prevent mosquito breeding. Tell your public officials to stop spraying pesticides and adopt a mosquito management plan that protects public health and the environment. The problem with mosquito pesticides. Two classes of insecticides are favored by mosquito spray programs—organophosphates and synthetic pyrethroids. In order to better target flying mosquitoes, adulticides are generally applied as ultra-low-volume (ULV) formulations that will float in the air longer than usual.  Pesticides are toxic chemicals and can exacerbate respiratory illnesses like Covid-19.Organophosphates, which include malathion (Fyfanon), naled (Dibrom), and chlorpyrifos (Mosquitomist for public health uses only) are highly toxic pesticides that affect the central nervous, cardiovascular, and respiratory systems. Symptoms of poisoning in humans include numbness, tingling sensations, headache, dizziness, tremors, nausea, abdominal cramps, sweating, incoordination, blurred vision, difficulty breathing, slow heartbeat, loss of consciousness, incontinence, convulsions, and death. Some organophosphates have been linked to […]

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From Udder to Table: Toxic Pesticides Found in Conventional Milk, Not Organic Milk

Thursday, July 9th, 2020

(Beyond Pesticides, July 9, 2020) Conventional U.S. milk contains growth hormones, antibiotics, and low to elevated levels of pesticides not found in organic milk, according to a study published in the journal of Public Health Nutrition by Emory University researchers. Milk can bioaccumulate certain organic pollutants, making it a valuable medium to assess what chemical we might be ingesting daily. With milk being one of the most consumed beverages in the U.S., in addition to its use in other popular drinks (i.e., coffee and tea), this study discloses widespread contamination and highlights the need for improved regulation. Researchers in the study note, “To our knowledge, the present study is the first study to compare levels of pesticide in the U.S. milk supply by production method (conventional vs. organic). It is also the first in a decade to measure antibiotic and hormone levels and compare them by milk production type.”  The market for conventional milk, produced in chemical-intensive agriculture, is declining, but the demand for organic milk is increasing due to concerns over chemical contamination in consumer products from pesticides and other toxic chemicals. Although the U.S. Environmental Protection Agency (EPA) sets limits for pesticide residues in food products, the agency […]

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With 400,000 Malaria Deaths Worldwide, Insect Resistance to Mosquito Pesticides Calls for Urgent Need to Shift to Alternative Management Strategies

Wednesday, July 8th, 2020

(Beyond Pesticides, July 8, 2020) Efforts to control the transmission of malaria are encountering a big, though predictable, problem: the mosquitoes that transmit malaria are developing resistance to at least five of the insecticides that have been central to limiting transmission of the disease. A study released in late June reveals a dramatic increase in resistance to pyrethroid insecticides and DDT across sub-Saharan Africa. This signals the failure of a mainstay chemical approach to the spread of malarial mosquitoes; this same problem — resistance — is happening with chemical management of agricultural pests and weeds, and with antibiotics to treat human bacterial infections. This study underscores a point Beyond Pesticides has made repeatedly: resistance to pesticides (whether insecticides, herbicides, biocides, fungicides, or medical antibiotics) is nearly inevitable. The solution to containing the spread of malaria lies not in the use of more and different chemicals, but in nontoxic approaches that respect nature and ecological balance. Malaria is a sometimes deadly disease caused by female Anopheles mosquitoes infected with any of four varieties of the Plasmodium parasite. The disease kills roughly 400,000 people annually, with half that mortality in sub-Saharan Africa. The U.S. sees approximately 2,000 cases of malaria annually, primarily in […]

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Endocrine Disrupting Chemicals, Including Pesticides, Have a Multi-Generational Impact on Commercially Beneficial Inland Silverside Fish

Thursday, July 2nd, 2020

(Beyond Pesticides, July 2, 2020) Exposure to low levels of endocrine-disrupting chemicals commonly in waterways, including pesticides, can impact future generations of major commercial fish, despite no direct exposure to the chemicals, according to research published in the journal Frontiers in Marine Science by Oregon State University (OSU) researchers. Many studies assess the acute or chronic health implications associated with endocrine disruptors on a single generation but lack information on multi-generational impacts that can provide vital information on the fundamental survivability or fitness of many species. This study highlights the significance of understanding the implications of endocrine disruptors, even at low levels of exposure, as parental exposure can have adverse epigenetic consequences for future generations. Kaley Major, a Ph.D. fellow at Oregon State University (OSU) and lead research author, explains, “What t[his] gets at is something your grandparents may have come into contact within their environment can still be affecting the overall structure of your DNA in your life today.” Endocrine disruptors are xenobiotics (i.e., chemical substances like toxic pesticides foreign to an organism or ecosystem). Past research shows exposures to endocrine-disrupting chemicals can adversely impact human, animal—and thus environmental—health, by altering the natural hormones in the body responsible for […]

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Household Pesticide Exposure Associated with the Risk of Developing Depression Symptoms

Thursday, June 18th, 2020

(Beyond Pesticides, June 18, 2020) Residential exposure to household pesticide products increases the risk of developing symptoms associated with depression, according to a study published in Environmental Research by researchers at Medical College of Georgia—Augusta University, School of Medicine—Jinan University, and Guangzhou Center for Disease Control and Prevention (CDC), China. Research on pesticide-induced diseases commonly investigates pesticide exposure concerning the development of various physical illnesses, and previous studies show there are occupational risks of developing depression, especially in agriculture where pesticide use is rampant. However, there is a lack of information connecting pesticide exposure to the subsequent psychological (psychiatric) effects on the general population. Additionally, household pesticide exposure varies from occupational exposure via exposure frequency, duration, intensity, and type. This research highlights the significance of researching potential mental health effects resulting from pesticide exposure, especially as society tends to rank mental health risks second to physical health. The study’s scientists note, “Our results highlight the importance of the cautious use of household pesticides because the chronic effects of poisoning may contribute to an elevated risk of depression.”  According to the World Health Organization (WHO), depression affects 322 million people globally, with the number of diagnosed patients increasing by 18.4% from 2005 to 2015. Although the etiology of depression—and […]

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Dogs (Canis familiaris) – Research Tracks Dogs’ Exposure to Contaminants in the Home, Serves as Sentinel Species for Chemical-Induced Human Diseases

Thursday, June 11th, 2020

(Beyond Pesticides, June 11, 2020) Researchers at North Carolina State University (NC State) and Duke University found that dogs can potentially operate as a sentinel, or indicator, species for environmental contaminate exposure – and subsequent diseases – in humans using silicone monitoring devices (i.e., wristbands, collars, etc.), according to research published in Environmental Science & Technology. Although scientists commonly use silicone devices to gauge organic contaminant exposure levels in epidemiological studies, the identification of chronic human diseases from pollutants remains challenging. Anthropoid (human) diseases can take many years to develop, even after initial contaminant exposure. However, dogs can develop comparable anthropomorphic diseases from susceptibility to the same environmental contaminants, but at a much quicker pace. This research highlights the significance of researching disease identification methods, mutual amid multiple species, to mitigate challenges surrounding long disease latency periods. Matthew Breen, Ph.D., professor of comparative oncology genetics at NC State, asserts, “If we develop ways to correlate dog disease with their exposures over time, it may allow human-health professionals to mitigate these exposures for both species. This study reinforces the concept of One Health, demonstrating that in addition to being our closest animal companions, our dogs are truly a sentinel species for health.” As […]

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Occupational Exposure to Pesticides, and Other Environmental Chemicals Increase Risk of Developing ALS

Thursday, May 28th, 2020

(Beyond Pesticides, May 28, 2020) Exposure to agricultural and industrial pesticides, solvents (thinners), electromagnetic fields, and heavy metals predispose humans to amyotrophic lateral sclerosis (ALS), according to an Italian research study, “Environmental and Occupational Risk Factors of Amyotrophic Lateral Sclerosis: A Population-Based Case-Control Study,” published in the International Journal of Environmental Research and Public Health. Although research supports ALS’s genetic etiology, epidemiologic research associating ALS risks and to environmental, or work-related risk factors (i.e., pesticide use, pollutant exposure, heavy metal exposure, etc.) has been inconsistent and non-definitive. This research demonstrates the importance of assessing aggregate health risks associated with occupational pesticide exposure, especially when determining potential exposure routes in specific occupational sectors. In the study, researchers note, “In particular, having an occupation in the agricultural sector, especially with a long duration of the working activity as well as occupational exposure to some chemicals…might increase ALS risk.” While scientists extensively study the epidemiology of amyotrophic lateral sclerosis (ALS)—a rare, yet fatal neurodegenerative disease—occupational and environmental hazards inducing random (sporadic) or hereditary ALS diagnoses remain vague. With researchers predicting a global ALS incidence increase of 69% by 2040, identifying ALS’s causal factors are important to future research. In this research, Italian researchers conducted a case-control, […]

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