(Beyond Pesticides, August 7, 2020) Research out of the Silent Spring Institute identifies 28 registered pesticides linked with development of mammary gland tumors in animal studies. Study authors Bethsaida Cardona and Ruthann Rudel also report that many of the pesticides they investigated behave as endocrine disruptors; breast cancers in humans are significantly influenced by hormones generated by the endocrine system. The Environmental Protection Agency (EPA) acknowledges that nine of these 28 pesticide compounds cause mammary tumors, but dismisses the evidence of the other 19. The results of this research, published in the journal Molecular and Cellular Endocrinology, evince Beyond Pesticides’ long-standing argument that the risk assessment process used by EPA for its pesticide registration process is substantially inadequate to protect human health. The co-authors cite, as the catalyst for this research project, a Cape Cod resident’s outreach to the Silent Spring Institute several years ago, asking for information about the herbicide triclopyr because utility companies wanted to spray it on vegetation below local power lines. (The compound has also been used by the logging industry in the Pacific Northwest.) They reviewed more than 400 EPA pesticide documents on the health impacts of many registered pesticides for this research, conducted as part […]

(Beyond Pesticides, July 2, 2020) Exposure to low levels of endocrine-disrupting chemicals commonly in waterways, including pesticides, can impact future generations of major commercial fish, despite no direct exposure to the chemicals, according to research published in the journal Frontiers in Marine Science by Oregon State University (OSU) researchers. Many studies assess the acute or chronic health implications associated with endocrine disruptors on a single generation but lack information on multi-generational impacts that can provide vital information on the fundamental survivability or fitness of many species. This study highlights the significance of understanding the implications of endocrine disruptors, even at low levels of exposure, as parental exposure can have adverse epigenetic consequences for future generations. Kaley Major, a Ph.D. fellow at Oregon State University (OSU) and lead research author, explains, “What t[his] gets at is something your grandparents may have come into contact within their environment can still be affecting the overall structure of your DNA in your life today.” Endocrine disruptors are xenobiotics (i.e., chemical substances like toxic pesticides foreign to an organism or ecosystem). Past research shows exposures to endocrine-disrupting chemicals can adversely impact human, animal—and thus environmental—health, by altering the natural hormones in the body responsible for […]

(Beyond Pesticides, June 30, 2020) A review of scientific literature on the toxic effect of environmental contaminants—including pesticides—published in the journal Toxicological Science, “The Impact of Environmental Chemicals on the Gut Microbiome,” associates these chemicals to changes in the gut microbiome and other adverse health implications. The review, by researchers at the University of Illinois, looks at how environmental contaminants adversely effects and reinforce chemical disruption of the gut microbiome. It highlights the importance of evaluating how environmental contaminants, like pesticides, impact body regulation by gut microbiota. The study has significant implications for considerations that should be, but are not currently, a part of pesticide review and registration by the U.S. Environmental Protection Agency (EPA). Gut microbiota plays a crucial role in lifelong digestion, immune, and central nervous system regulation, as wells as other bodily functions. Through the gut biome, pesticide exposure can enhance or exacerbate, the adverse effects of additional environmental toxicants on the body. Since the gut microbiome shapes metabolism, it can mediate some toxic effects of environmental chemicals. However, with prolonged exposure to various environmental contaminants, critical chemical-induced changes may occur in the gut microbes, influencing adverse health outcomes. Karen Chiu, Ph.D., a graduate research fellow at the […]

(Beyond Pesticides, June 18, 2020) Residential exposure to household pesticide products increases the risk of developing symptoms associated with depression, according to a study published in Environmental Research by researchers at Medical College of Georgia—Augusta University, School of Medicine—Jinan University, and Guangzhou Center for Disease Control and Prevention (CDC), China. Research on pesticide-induced diseases commonly investigates pesticide exposure concerning the development of various physical illnesses, and previous studies show there are occupational risks of developing depression, especially in agriculture where pesticide use is rampant. However, there is a lack of information connecting pesticide exposure to the subsequent psychological (psychiatric) effects on the general population. Additionally, household pesticide exposure varies from occupational exposure via exposure frequency, duration, intensity, and type. This research highlights the significance of researching potential mental health effects resulting from pesticide exposure, especially as society tends to rank mental health risks second to physical health. The study’s scientists note, “Our results highlight the importance of the cautious use of household pesticides because the chronic effects of poisoning may contribute to an elevated risk of depression.”  According to the World Health Organization (WHO), depression affects 322 million people globally, with the number of diagnosed patients increasing by 18.4% from 2005 to 2015. Although the etiology of depression—and […]

(Beyond Pesticides, June 11, 2020) Researchers at North Carolina State University (NC State) and Duke University found that dogs can potentially operate as a sentinel, or indicator, species for environmental contaminate exposure – and subsequent diseases – in humans using silicone monitoring devices (i.e., wristbands, collars, etc.), according to research published in Environmental Science & Technology. Although scientists commonly use silicone devices to gauge organic contaminant exposure levels in epidemiological studies, the identification of chronic human diseases from pollutants remains challenging. Anthropoid (human) diseases can take many years to develop, even after initial contaminant exposure. However, dogs can develop comparable anthropomorphic diseases from susceptibility to the same environmental contaminants, but at a much quicker pace. This research highlights the significance of researching disease identification methods, mutual amid multiple species, to mitigate challenges surrounding long disease latency periods. Matthew Breen, Ph.D., professor of comparative oncology genetics at NC State, asserts, “If we develop ways to correlate dog disease with their exposures over time, it may allow human-health professionals to mitigate these exposures for both species. This study reinforces the concept of One Health, demonstrating that in addition to being our closest animal companions, our dogs are truly a sentinel species for health.” As […]

(Beyond Pesticides, June 2, 2020) During the April meeting of the National Organic Standards Board (NOSB), there was near-unanimous sentiment expressed by NOSB members and stakeholders that the failure of the National Organic Program at USDA to act on NOSB recommendations regarding so-called “inert” ingredients hurts organic producers and consumers and the environment. The NOSB has only one alternative left to force USDA action—denying relisting at the Fall meeting. Tell the National Organic Program and USDA Secretary Sonny Perdue to initiate action to begin NOSB review of “inerts” now. Dr. Asa Bradman, who summarized the issue for the NOSB at the Spring 2020 meeting, is an expert in environmental health, and as part of his day job, leads studies focusing on pesticides, flame retardants, metals, emerging pollutants, VOCs, indoor air quality and other contaminants. As he said at the meeting, “These are often active ingredients.” In fact, the ingredients not listed on a label of a pesticide product—which are not fully reviewed for their adverse effects—may be the most toxic chemicals in the formulation. Recent research, Toxicity of formulants and heavy metals in glyphosate-based herbicides and other pesticides (Toxicology Reports 5, 2018), by Defarge, de Vendômois, and Séralini demonstrates the need to […]

(Beyond Pesticides, April 20, 2020) As USDA takes public comments on its updated dietary guidelines, it important that sustainable, regenerative organic food production practices are an integral part. Since 1990, Congress has required an every-five-years review of its Dietary Guidelines — recommendations intended to promote public health and prevent chronic diseases. The next review and a draft updated version, the 2020–2025 Dietary Guidelines for Americans, is currently underway. USDA says that the dietary guidelines provide “information that helps Americans make healthy choices for themselves and their families.” In order to make healthy food choices, the guidelines must go beyond the traditional parameters to include how the food is produced. How food is produced affects the health of Americans not only as a result of the nutritional quality of the food, but also due to environmental contamination. Sign the petition to USDA and send a letter to Congress. Tell them that organic food must be emphasized in new dietary guidelines. Although research on the nutritional density of organic produce is equivocal, showing some higher levels of antioxidants, results are decidedly clear for animal products. Pastured organic animal products—including beef, lamb, pork, dairy, poultry, and eggs—have been shown to be superior to that of products of […]

(Beyond Pesticides, March 2, 2020) Deadline today! Tell EPA to Ban Atrazine; Protect Children and Frogs from this Endocrine Disrupting Pesticide. Atrazine, the second most-used herbicide in the U.S., is an insidious poison. Atrazine is known for producing developmental abnormalities in frogs. It also affects the endocrine system and reproductive biology of humans. In addition to its agricultural uses on corn, sorghum, and sugar cane, atrazine is also used on home lawns, school grounds, and parks, where exposure to children is common. Nontoxic alternatives are available for all of these uses. Act today, March 2. Sign the petition demanding that EPA ban atrazine and its cousins simazine and propazine. Act today! Beyond Pesticides will submit comments: Docket: EPA-HQ-OPP-2017-0750 (FRL-10002-92) Petition to EPA’s Office of Pesticide Programs: We have serious concerns with the proposed interim decisions on reregistration of three triazine pesticides: atrazine, simazine, and propazine. These triazines are highly mobile and persistent in the environment and have been linked to numerous adverse health and environmental effects which have motivated numerous public interest campaigns to ban their use in the U.S. as well as in Europe. The Draft Ecological Risk Assessments for the Registration Review of Atrazine, Simazine, and Propazine dated October 5, 2016 […]

(Beyond Pesticides, February 27, 2020) A new report finds that as birds and pollinators continue to decline, and chronic diseases remain on the rise, the global agrichemical industry is raking in billions of dollars from hazardous pesticides that contribute to these crises. A joint investigation from Unearthed and Public Eye finds that 35% of pesticide sales from the largest agrichemical corporations are made from the most toxic pesticides on the market. Pesticide production was a $57.6 billion market in 2018, according to the report. While the profits of the industry are privatized, the public health and environmental effects are broad. Studies conducted over the last decade show that the impacts of hazardous pesticide use dwarf the market for these chemicals. The impact of pesticides on public health results in a drag on the economy. Earlier this year, research from the New York University Grossman School of Medicine found that children’s exposure to organophosphate insecticides was estimated to result in over 26 million lost IQ points and over 110,000 cases of intellectual disability, totaling roughly $735 billion in economic costs each year. A 2019 study from the same scientists determined that endocrine disrupting chemicals, including organophosphates and organochlorine pesticides, were attributable […]

(Beyond Pesticides, February 11, 2020) A new study, published in the journal Cell Host & Microbe, homes in on the impact of the toxic herbicide atrazine on wasp gut microbiology and pesticide resistance. Intriguingly, researchers found that exposure to atrazine changed the composition of gut bacteria in individual wasps and shifts in gut flora were heritable. This study not only represents one of the first evolutionary studies on symbiont-mediated pesticide resistance, it also provides fodder for future research regarding the implications of exposure to xenobiotics (i.e., chemical substances like toxic pesticides foreign to an organism or ecosystem) for other gut bacteria hosts – such as honey bees and humans. Researchers utilized the hymenopteran insect model Nasonia vitripennis to analyze the effect of subtoxic exposure to atrazine across 36 generations. They reestablished a baseline of toxicity by experimenting with concentrations of atrazine to find the level at which 50% of the population died (LC50). During initial trials, some of the wasps were kept in a germ-free (GF) environment. The authors observed a higher mortality rate among the germ-free population, indicating that gut microbes assist with detoxification.   Early generations of wasps in the study received a field-realistic dose of atrazine (300 […]

(Beyond Pesticides, January 29, 2020) A study of male breast cancer (MBC) in Scotland reports an alarming, increasing trend of this rare disease – especially in agricultural areas. While only accounting for 1% of diagnosed breast cancer, MBC forms in the breast tissue of men and is often fatal because of delayed diagnosis and lack of research on male-specific treatment. The authors point to risk factors that include increased exposure to endocrine-disrupting chemicals, such as pesticides, and a need for further study. Researchers analyzed data from the Information Services Scotland database spanning from 1992-2017. Results showed that incidence of breast cancer in men rose with age, and that the total number and age-adjusted incidence of MBC increased in the last 25 years. Overall, the incidence rose by 38.5%. There was a total of 558 diagnoses in Scotland in the entire period. The trend is clearest in certain regions, including the North of Scotland and some rural areas. “Within the confines of this observational study, reasons for these regional differences are difficult to reconcile, but potential explanations are offered,” the authors write, “Exposure to environmental compounds that mimic oestrogens (so-called Endocrine-Disrupting Chemicals; (EDCs)) might be exacerbated in areas of higher agricultural […]

(Beyond Pesticides, January 16, 2020) Exposure to environmental chemicals in the U.S. since the turn of the century has resulted in millions of lost IQ points, hundreds of thousands of cases of intellectual disability, and trillions of dollars of lost economic activity. This is according to a study led by a team of scientists at the New York University Grossman School of Medicine, published in the journal Molecular and Cellular Endocrinology. “Although people argue against costly regulations, unrestricted use of these chemicals is far more expensive in the long run, with American children bearing the largest burden,” says senior study author Leonardo Trasande, MD, MPP in a press release. Exposure to environmental chemicals can result in neurotoxic effects. Prenatal exposure represents a critical window when these effects can be particularly pronounced and result in lasting damage to a child. Researchers focused their study on contact with mercury, lead, organophosphate pesticides, and flame retardants in the womb. Biomonitoring data from a long-running Centers for Disease Control and Prevention study on environmental chemicals was used to determine exposure levels. Because each chemical results in differing levels of intellectual damage, each was assigned an IQ impact based on past research. For example, scientists indicated […]

(Beyond Pesticides, January 15, 2019) A study published in the journal Environment International, Association of urinary metabolites of organophosphate and pyrethroid insecticides, and phenoxy herbicides with endometriosis, is the first of its kind. Researchers considered the endocrine-disrupting properties of pesticides (such as reduced sperm counts) and investigated whether there might be a relationship between pesticide exposure and endometriosis. Endometriosis is an estrogen-dependent gynecologic disease that affects about 176 million women globally. It can cause extreme pain and infertility as well as increased risk for cancer and cardiovascular diseases. This study finds a positive correlation between some pesticide metabolites and endometriosis, though authors encourage further study to corroborate the findings. Researchers examined exposure to 11 “universal pesticides” and their metabolites and its relationship to endometriosis in 492 reproductive-age women recruited from 14 surgical centers in Utah and California from 2007-2009. The women at these clinics were scheduled for laparoscopy or laparotomy—the “gold standard” for identifying endometriosis is through these surgeries. The study compares results from the clinical cohort to a group of women in the same age bracket from areas surrounding the participating clinics. 619 urine samples were analyzed from the operative and population cohorts. This study detected six of the […]

(Beyond Pesticides, December 24, 2019) The staff and board of Beyond Pesticides wish our members and network all the best for the holiday season and new year. We look forward to working with you in the new year to meet the serious environmental and public health challenges with truly organic solutions. Our accomplishments are your victories. We are seeing the outcomes in communities across the country—the adoption of organic land management policies and practices that eliminate toxic pesticides, protect children and families, and protect the local ecology. Beyond Pesticides’ program responds to the urgent need to address the public health and environmental crises of our times—climate crisis, insect apocalypse, pesticide-induced illness, and the dramatic decline in biodiversity. With on-the-ground practices and local policies, we replace fossil fuel-based, toxic, synthetic pesticides and fertilizers with organic management strategies. TAKING A STAND Beyond Pesticides’ program supports a clear message: End toxic pesticide use and embrace organic practices and policies that respect the power of nature to heal— in the face of devastating and destructive toxic chemical-dependency. This past year has again elevated important public discourse on the threats that pesticides pose to health and the environment. We see in the mainstream culture increased […]

(Beyond Pesticides, November 20, 2019) Continuing its marathon of deregulation to benefit the chemical industry, the Trump administration’s Environmental Protection Agency (EPA) released a memo announcing its proposal to increase the amount of the weed killer atrazine allowed in U.S. waterways by 50% during the chemical’s registration review—a stark reversal of previous proposals to significantly reduce atrazine levels in the environment. The proposal comes after agrichemical giant Syngenta and the National Corn Growers Association requested that EPA dismiss independent research regarding the adverse impact of atrazine.  Atrazine, a broadleaf herbicide, is linked to endocrine disruption, neuropathy, and cancer. It disrupts the sexual development of frogs at levels far below the current allowed concentrations by EPA. Studies by Tyrone Hayes, Ph.D., University of California, Berkeley, and others have shown that concentrations as low as 0.1ppb interfere with mammary gland development in the breast of mammals. In 2009, a study linked birth defects like gastroschisis and choanal atresia to time of conception and the relative concentrations of atrazine and other pesticides in drinking water. The current Concentration Equivalent Level of Concern (CELOC), a measure in place to protect aquatic organisms, for atrazine is a 60-day average concentration of 10 ppb. EPA’s proposal […]

(Beyond Pesticides, October 2, 2019) New data gleaned from the Kuakini Honolulu Heart Program — a longitudinal study of men of Japanese descent living on Oahu — demonstrate that occupational exposure to high levels of pesticides can increase risks for cardiovascular disease (CVD) in the forms of coronary heart disease (CHD) or stroke (CVA, or cerebrovascular accident). Further, researchers determined both that workers who experience high-level exposures may not experience such effects for years afterward, and that the maximum subsequent effects were seen within a decade of exposure. The study’s conclusion highlights the importance of pesticide applicator use of protective gear when handling toxic pesticides. These risks and harms could be eliminated through a transition to non-chemical means for pest control in agriculture, land management, and home and personal practices. The Kuakini Honolulu Heart Program, after enrolling more than 8,000 Japanese-American men, 45–68 years old and living on Oahu, Hawaii between 1965 and 1968, has continued to examine and interview these subjects, and document morbidity and mortality among them. This study, which performed statistical analyses on 7,557 of the subjects, is the longest longitudinal study of cardiovascular disease and any association with chronic occupational pesticide exposure, taking into account epidemiologic risk […]

(Beyond Pesticides, August 30, 2019) The indictment of organophosphate pesticides gained more traction with the publication, in the Proceedings of the National Academy of Sciences, of a new research study out of the University of California, Berkeley. The research, among the first to use advanced brain imaging to assess cortical activation, shows altered brain activity, during tasks that call on executive function, in teenagers from California’s Salinas Valley (the site of significant organophosphate use) whose mothers were exposed prenatally. The UC Berkeley study underscores the slow-motion calamity of the Trump administration Environmental Protection Agency’s (EPA’s) failure to ban the use of this class of pesticides, and of chlorpyrifos in particular, which compounds carry extreme risks for children. The effects of this prenatal exposure continue to unfold during children’s critical developmental periods. Researchers used fNIRS (functional near-infrared spectroscopy) imaging to monitor blood flow in the brains of the teens, 15–17, born and raised in the Salinas Valley. They used data from the California Pesticide Use Reporting program (which documents locations and times of pesticide spraying) to estimate the subjects’ mothers’ proximity to organophosphate (OP) applications during pregnancy. The subject adolescents — estimated to have relatively high levels of prenatal exposure to organophosphates — […]

(Beyond Pesticides, July 3, 2019) A disturbing association between urinary triclosan concentrations and osteoporosis has been identified in an epidemiological study. Drawing from the National Health and Nutrition Examination Survey (NHANES) results for 1,848 U.S. adult women, the authors conclude that higher concentrations of urinary triclosan are associated with lower bone mass density and higher prevalence of osteoporosis among U.S. adult women. The study, published in the Journal of Clinical Endocrinology and Metabolism, adds weight to previous laboratory results, which showed that endocrine-disrupting chemicals such as triclosan can interfere with bone metabolism. Triclosan and its byproducts are known endocrine disruptors and have been shown in laboratory studies to interfere with collagen and bone structure. Taken together with previous findings, the new epidemiological results demonstrate that the ubiquitous endocrine disruptor triclosan “could lead to lower BMD [benchmark dose] and increased prevalence of osteoporosis in U.S. adult women.” Triclosan is used as an antimicrobial agent in products regulated by both the Environmental Protection Agency (EPA) and the Food and Drug Administration (FDA), and cumulative exposure to triclosan registered by both agencies pose unacceptable risks to human health and the environment. Triclosan exposure has become so common that it has shown up in […]

(Beyond Pesticides, July 1, 2019) France made a decision in May to ban a widely-used fungicide because it damages the endocrine system. In contrast, there has been a stark failure to protect health in the U.S. Despite a Congressional mandate, EPA is not acting on endocrine disruptors linked to infertility and other reproductive disorders, diabetes, cardiovascular disease, obesity, and early puberty, as well as attention deficit hyperactivity disorder (ADHD), Parkinson’s, Alzheimer’s, and childhood and adult cancers. This is a tragedy. Ask your elected members of Congress to demand that EPA tests and acts on regulatory endocrine disruptors as required by law. In 1998, following a mandate in the Food Quality Protection Act (FQPA) of 1996, EPA established a program to screen and test pesticides and other widespread chemical substances for endocrine disrupting effects. Despite operating for 21 years, the Endocrine Disruptor Screening Program (EDSP) has made little progress in reviewing and regulating endocrine-disrupting pesticides.  As of 2019, the program has stalled entirely. To ensure appropriate follow-through, Congress gave EPA a timeline to: develop a peer-reviewed screening and testing plan with public input not later than two years after enactment (August 1998); implement screening and testing not later than three years after […]

(Beyond Pesticides, June 7, 2019) Fruit orchards and vineyards endure some of the most intensive chemical management in all of agriculture. What has not been investigated — until now — is how pesticide drift from such agricultural sites may be affecting nearby public spaces. A recent, first-of-its-kind study out of northern Italy tested 71 public playgrounds near to apple orchards and vineyards in four valleys of the North Tyrol, and finds that 45% are contaminated with a single pesticide, and 24% by more than one. Study authors note that the playground contamination will likely grow worse over the course of the growing season. This would likely amplify the impacts of such chemical trespass on nearby public spaces, never mind the varieties of harm to the sites themselves and the food produced on them. Organic agriculture, of course, remedies all these concerns. The study randomly chose 71 public playgrounds in the four South Tyrolean regions, and analyzed grass samples for potential contamination by 315 different pesticides. Because pesticides applied to agricultural fields, orchards, and vineyards are easily volatized, carried aloft by wind, and/or washed by rain off of the target site, the study also evaluated the impacts of those (and other) factors […]

(Beyond Pesticides, May 23, 2019) On Monday in the conclusion of a lawsuit, the U.S. Environmental Protection Agency (EPA) announced the final notices of cancellation on the registration of twelve neonicotinoid pesticide products in the Federal Register, each of which contains chlothianidin or thiamathoxam as an active ingredient. The decision to pull these products from the market was required as part of a legal settlement under the Endangered Species Act (ESA) in December 2018 of a successful case, Ellis v. EPA, brought by beekeeper Steve Ellis and a coalition of other beekeepers and environmental groups, including Beyond Pesticides. The case establishes a legal precedent in which the court required action to address the bee-toxic effects of pesticides; however, the effect of the settlement and its impact on overall neonicotinoid and other systemic insecticide use is limited. For all but two of the twelve canceled products, a nearly identical surrogate remains actively registered. Furthermore, the fact remains that there are hundreds more products containing the active ingredients targeted by the lawsuit that have not been removed in any capacity – 106 products containing clothianidin and 95 containing thiamethoxam remain untouched on the market. Breaking down the impacts of the EPA ruling even […]

(Beyond Pesticides, May 2, 2019) Researchers have documented an increase in food and drinking water residues of neonicotinoids, insecticides linked to breast cancer. Using the Pesticide Data Program (PDP), 1999-2015, of the U.S. Department of Agriculture, the researchers identified near-peak detection frequencies in 2015, after a decline from 2008-2013. Imidacloprid remains the most common neonicotinoid detected across imported commodities, while the neonicotinoids clothianidin, thiamethoxam, acetamiprid, and flonicamid are replacing imidacloprid in domestic production. Authors note that these newer neonicotinoids are potentially more toxic than imidacloprid, raising concerns for understudied human health and environmental impacts. The study, Trends in neonicotinoid pesticide residues in food and water in the United States, 1999–2015, published in the journal Environmental Health, finds the highest detection frequencies for neonicotinoids in drinking water, with 30% of treated drinking water turning out positive for imidacloprid in 2011. Certain fruits and vegetables are also frequently contaminated by neonicotinoids, with detection frequencies ranging from 20% to as high as 57% in the case of imidacloprid on cauliflower. While the study points to specific fruits and vegetables as posing higher risk, the main message reaches beyond individual commodity or individual neonicotinoid results. Authors uncover a systematic increase in detection of neonicotinoid […]

(Beyond Pesticides, April 26, 2019) Research by the youth participatory action team of the CHAMACOS of the Salinas Evaluating Chemicals in Homes and Agriculture (COSECHA) reveals that teenagers in the Salinas Valley, California are routinely exposed to concerning levels of multiple toxic pesticides, several of them known endocrine disruptors. In an interview with Kion News, COSECHA research director Kimberly Parra remarked that the study is especially important because teenagers are in a stage of rapid reproductive development. As the study authors emphasize, it is their developmental stage that makes teenagers more vulnerable to the effects of endocrine disrupting pesticides, with potentially devastating consequences for lifelong health. The COSECHA study quantifies exposure to 72 pesticides, captured through volatile-trapping silicone wristbands, across 97 teenage girls living in various areas of the Salinas Valley region. Of the 72 pesticides analyzed, authors report that subjects are exposed to as many as 20 and an average of 8 pesticides over one week of routine indoor and outdoor activity. Given the well-documented dangers of pesticide co-exposures, these multiple-exposure findings are particularly concerning. Ranking the highest for prevalence among the studied pesticides is fipronil sulfide, a breakdown product of the insecticide fipronil, detected in 86.6% of the analyzed wristbands. […]