(Beyond Pesticides, June 19, 2015) A new study directly links exposure to dichlorodiphenyltrichloroethane (DDT) in utero to the development of breast cancer later in life. Published in the Journal of Clinical Endocrinology and Metabolism, the study looked at data that were taken from a California program that  evaluated  samples from women during 1960s, when DDT use was popular. DDT is known to be an endocrine disruptor, and is linked to serious health effects. Although DDT has been banned for many years, residues still linger in certain areas of the U.S. and continue to cause environmental and health hazards. The recent study, titled DDT Exposure in Utero and Breast Cancer,  focuses on 118 mothers who were members of Kaiser Foundation Health Plan from 1959-1967 and had daughters that were diagnosed with breast cancer by their 50s. Stored blood samples from these mothers gave researchers an idea of how much DDT they were exposed to during pregnancy or soon after giving birth. They found that elevated levels of DDT in the mother’s blood led to a four-fold increase in the daughter’s risk of developing breast cancer. Among those with cancer, 83% had a form of cancer called estrogen positive breast cancer, which […]

(Beyond Pesticides, June 16, 2015) France’s Ecology Minister Segolene Royal announced Sunday a  call to  stop  the sale of the popular Monsanto herbicide Roundup (glyphosate) from garden centers. The announcement comes just a couple of  months after the active ingredient, glyphosate, was classified in March as “probably carcinogenic to humans” by the United Nation’s International Agency for Research on Cancer (IARC). “France must be on the offensive with regards to the banning of pesticides,” Royal said on French television. “I have asked garden centers to stop putting Monsanto’s Roundup on sale” in self-service aisles, she added. The announcement comes after a request by French consumer association CLCV (Consumption, Housing and Environment – Consommation, Logement et Cadre de vie)  to French and European officials to stop selling glyphosate-based products to amateur gardeners. Royal also announced last week that from January 2018 onwards, phytosanitary products —used to control plant diseases— would only be available to amateur gardeners “through an intermediary or a certified vendor.” Glyphosate is touted as a “low toxicity” chemical and “safer” than other chemicals by EPA and industry and is widely used in food production and on lawns, gardens, parks, and children’s playing fields. However, IARC’s new classification of […]

(Beyond Pesticides, May 28, 2015) The same day that trade representatives from United States met with Secretary-General Catherine Day of the European Commission (EC), she sent a letter to the EC’s Environment Director-General Karl Falkenberg telling him to scrap draft criteria that could have led to a ban on over 30 endocrine (hormone) disrupting chemical (EDCs) in the European Union (EU). As reported by The Guardian, with resources obtained by Pesticide Action Network- Europe (PAN-Europe), the U.S. Chambers of Commerce and European-based chemical manufacturers (including Dupont, Bayer, and BASF) pushed to change the EC’s criteria for evaluating EDCs because they fear it would impede EU-US negotiations on  the Transatlantic Trade and Investment Partnership (TTIP). Two regulations, one concerning “plant pest protectants” (EU 1107), and another on biocidal products (EU 528), should prohibit from use chemicals categorized as having endocrine disrupting properties that may cause adverse effects in humans. However, last year, when the EC released a roadmap for evaluating EDCs, recommendations fell far short of what health advocates assert that EU regulations require. Earlier this year, the Guardian reported that a scientific paper that would have adequately established ways to identify problematic EDCs was suppressed by EU officials at the […]

(Beyond Pesticides, May 7, 2015) The Pennsylvania Fish and Boat Commission (PFBC) has confirmed that a rare malignant tumor was found on a smallmouth bass caught in the Susquehanna River by an angler late last summer. The finding was confirmed by two independent laboratory tests, including the U.S. Fish and Wildlife Service (FWS) and the Aquatic Animal Health Laboratory at Michigan State University.  Although it only represents one individual fish from the overall population, it provides additional evidence —which includes the prevalence of intersex fish discovered last summer”” that the health of the fish community residing in the river is being compromised, according to PFBC executive director John Arway. Though the findings do not point to a specific cause for the cancer found on the smallmouth bass (SMB), agricultural pesticides, particularly endocrine disrupting chemicals, that have been found in the watershed, likely play a part in the rampant disease issues in SMB in the Susquehanna River. “As we continue to study the river, we find young-of-year and now adult bass with sores, lesions and more recently a cancerous tumor, all of which continue to negatively impact population levels and recreational fishing,” Mr. Arway said. “The weight-of-evidence continues to build a […]

(Beyond Pesticides, April 27, 2015) Last week, the United States Department of Agriculture (USDA) announced initiatives and energy programs to reduce greenhouse gas emissions, increase carbon sequestration, and expand renewable energy production in the agricultural and forestry sectors, but failed to stress the importance of moving away from chemical-intensive  agriculture toward organic methods. While the announcement doesn’t specifically mention “organic,” the meaning is still clear: chemical-based agricultural practices have contributed to climate change through heavy use of fossil fuels —both directly on the farm and in the manufacturing of pesticides and fertilizers— and through degradation of the soil, which releases carbon. Now, USDA is suggesting the use of conservation tilling, or no-till practices, along with cover cropping and natural management of organic inputs to the soil — in other words, organic agriculture. USDA outlined ten “building blocks” that aim to lead us away from climate change. The first two of these ten could, if interpreted from an organic practice perspective,  address the necessity to change  chemical-intensive agricultural practices. The first “building block” is soil health. The stated goal is to improve soil resilience, therefore increasing productivity, by promoting conservation tillage or no-till farming. The initiative suggests planting cover crops, planting […]

(Beyond Pesticides, March 13, 2015) Exposure to endocrine (hormone) disrupting chemicals (EDC) results in approximately € 150 billion ($162 billion) in health care costs in the European Union each year, according to panels of scientists tasked by the EU Commission to study their impact. “The shocking thing is that the major component of that cost is related to the loss of brain function in the next generation,” Philippe Grandjean, M.D. of Harvard University, one of the report’s authors, told the Guardian. EDCs, contained in common household products such as detergents, disinfectants, furniture, plastics, and pesticides, interfere with the body’s hormone system either by mimicking naturally produced hormones, blocking hormone receptors in cells, or effecting the transport, synthesis, metabolism or excretion of hormones. These impacts can result in devastating effects on one’s health, including behavioral and learning disorders, such as Attention Deficit Hyperactivity Disorder (ADHD), birth defects, obesity, early puberty, infertility, cardiovascular disease, and childhood and adult cancers. Nearly 100 percent of people have detectable amounts of EDCs in their bodies, according to the introductory guide to EDCs published by the Endocrine Society and IPEN. “Our brains need particular hormones to develop normally —the thyroid hormone and sex hormones like testosterone […]

(Beyond Pesticides, February 5, 2015) A brewing  battle in the European Union (EU) over removing from the market  Endocrine Disrupting Chemicals (EDC)s has  heated up. An investigative report in  The Guardian  reveals that a European Union (EU) scientific paper, prepared to assist in the development of new mandatory EDC risk assessment standards, was never made public. According to the report, EU Commission sources say the release of the paper was quashed as a result of chemical industry pressure and political influence. At the core of the debate lies two EU regulations, one concerning biocidal products (EU 528/2012) and the second on “plant pest protectants” (EU 1107/2009). Both of these regulations required the EU Commission to produce draft measures concerning specific scientific criteria for the determination of endocrine disrupting properties by December 14, 2013. Under the regulations, chemicals within the biocidal and plant pest protectant categories that are  categorized as having endocrine disrupting properties that may cause adverse effects in humans would be prohibited from use in the market place. As noted in the purpose and subject matter of the biocidal regulations, “The purpose of [the] Regulation is to improve the functioning of the internal market through the harmonization of the […]

(Beyond Pesticides, January 30, 2015) Extensive exposure to common chemicals may be linked to an earlier start of menopause, according to a new study out of Washington University School of Medicine in St. Louis. Researchers of the study found that women whose bodies have high levels of these chemicals, including three pesticides, experience menopause two to four years earlier than women with lower levels of the chemicals. The pesticides found to have a significant correlation with an early start in menopause were p,p’-DDE (a metabolite of DDT), β-hexachlorocyclohexane (a byproduct of the production of lindane), and mirex. All three pesticides are organochlorine insecticides or their breakdown products that have been banned for use  in the U.S., but continue to persist in the environment and in the food chain. The study, Persistent Organic Pollutants and Early Menopause in U.S. Women, published this week in the journal PLoS ONE, investigates the link between levels in blood and urine of 111 endocrine-disrupting chemicals (EDCs), or chemicals that interfere with the body’s hormonal activity, and focused on known reproductive toxicants or persistent environmental contaminants. The findings suggest a significant association between 15 chemicals —nine polychlorinated biphenyls (PCBs, which are industrial products), three pesticides, two […]

(Beyond Pesticides, December 16, 2014) Beyond Pesticides is sad to say goodbye to a dear friend and colleague, Theo Colborn, who at the age of 87, passed away on Sunday, December 14 at home surrounded by her family. Dr. Colborn is author of the groundbreaking book Our Stolen Future, president of The Endocrine Disruption Exchange (TEDX) and Professor Emeritus at the University of Florida, Gainesville. She is the author of numerous scientific publications about compounds that interfere with hormones and other chemical messengers that control development in wildlife and humans. Her incisive research has demonstrated that endocrine disrupting chemicals alter development of the fetus in the womb by interfering with the natural hormonal signals directing fetal growth. Her work has prompted the enactment of new laws around the world. Dr. Colborn was presented with Beyond Pesticides’ highest honor, its Dragonfly Award, at the organization’s 25th Anniversary Gala in 2006, “For tireless dedication advancing knowledge and action to protect health and the environment.” Upon accepting the award, she said to those who chose her as the recipient that she would do her best not to let them down, and she hasn’t. One year later, she was honored by Time magazine as […]

(Beyond Pesticides, August 19, 2014) Newly released documents from the U.S. Food and Drug Administration (FDA) reveals that regulators expressed concerns over the safety of triclosan in Colgate Total toothpaste during the product’s registration in the mid-1990s. This information was provided to the public by FDA after a Freedom of Information Act request by the Natural Resources Defense Council (NRDC), and was posted on the agency’s website after inquiries from Bloomberg News. In addition to health effects previously identified by Beyond Pesticides, these documents raise concerns about the use of triclosan as an anti-gingivitis agent in toothpaste; a use which is not currently under scrutiny as FDA conducts its long-awaited health review of the chemical. Although FDA is requiring manufacturers of triclosan-containing soaps to prove that their products are not hazardous to humans and more effective than regular soap and water, triclosan formulated in toothpaste was not subject to a similar requirement as FDA had indicated that the chemical is effective as an anti-gingivitis agent. Colgate Total is the only brand of toothpaste on the market that still contains triclosan; GlaxoSmithKline, producer of Aquafresh and Sensodyne, removed triclosan from its toothpaste in 2009. And a focus on safer products seems […]

(Beyond Pesticides, August 12, 2014) The presence of triclosan in soaps and consumer products ranging from cutting boards to pencils means constant exposure to a chemical linked to a wide range of adverse health effects. New data to be presented at the 248th National Meeting and Exposition of the American Chemical Society, the world’s largest scientific society, reveals that 100% of pregnant women in a multiethnic urban population in Brooklyn, New York tested positive for triclosan in their urine. In half of the pregnant women tested, the chemical also showed up in umbilical cord blood. “We looked at the exposure of pregnant women and their fetuses to triclosan and triclocarban, two of the most commonly used germ-killers in soaps and other everyday products,” says study co-author Benny Pycke, Ph.D at Arizona State University. “We found triclosan in all of the urine samples from the pregnant women that we screened. We also detected it in about half of the umbilical cord blood samples we took, which means it transfers to fetuses.” In 2004, Beyond Pesticides published The Ubiquitous Triclosan, sounding the alarm on the rising use of an antibacterial chemical never adequately evaluated for adverse effects by the U.S. Food and […]

(Beyond Pesticides, July 29, 2014) A recent rise in drug resistant human pathogenic fungi may be fueled by the use of fungicides (pesticides that kill fungi) on agricultural fields, according to research led by Manchester University in the United Kingdom. Aspergillus, the genus of common soil-dwelling fungi analyzed by researchers, include an incredibly diverse group of mold species. Although some provide important commercial uses (such as in the production of citric acid, for instance), many species are pathogenic in humans, and can result in life-threatening lung infections. The rise of cross-resistant fungi is a serious concern for sensitive individuals with weakened immune systems, such as transplant patients, asthmatics, and those with leukemia. In the study, Occurrence of azole-resistant species of Aspergillus in the UK environment, UK scientists collected hundreds of samples across the country. Although no resistant strains were found in inner city locations, 1.7% of samples from rural agricultural areas had markers for drug resistance. However, previous research conducted in India in 2012 found resistant isolates in a number of urban and agricultural sites, including the soil beneath cotton trees and rice paddy fields, but also in air samples from hospital wards and even in the soil from flower […]

(Beyond Pesticides, July 15, 2014) More nutritional antioxidants, far fewer toxic pesticides; those are the results of a comprehensive meta-analysis on organic foods published yesterday in the British Journal of Nutrition.  Led by Carlo Leifort, Ph.D, at England’s Newcastle University, the analysis is a scientific rebuttal to a previous Stanford University review published in 2012, which found that there was little difference between the nutritional content of organic food over conventionally grown produce. Both studies found there to be fewer pesticides in organic products. While Stanford University’s review only looked at 200 studies, Dr. Leifert and his team of researchers expanded the scope of their meta-analysis to 343 studies, and also employed more robust analytic tools by analyzing the standardized mean differences of the data from the various studies. It shows very clearly how you grow your food has an impact,” said Dr. Leifert to The New York Times. “If you buy organic fruits and vegetables, you can be sure you have, on average, a higher amount of antioxidants at the same calorie level.” Antioxidants, compounds such as phenolic acids, flavanones, stilbenes, flavones, flavonols and anthocyanin, have been linked to lower risks of cancer and other diseases. For many, news […]

(Beyond Pesticides, July 7, 2014) A study led by the U.S. Geological Service (USGS) finds intersex fish in three watersheds of Pennsylvania and shows strong connections between these occurrences and increased pollution in waterways from endocrine-disrupting chemicals. The study, Reproductive Health Indicators of Fish from Pennsylvania Watersheds: Associations with Chemicals of Emerging Concern, examined three species of fish in three separate watersheds of Pennsylvania to assess whether characteristics caused by hormones and hormone-mimicking compounds, such as immature eggs in male fish, were present. In aquatic environments, the presence of these intersex characteristics is widely used as a biomarker for assessing exposure to estrogenic chemicals, as well as anti-androgenic chemicals which inhibit development of male characteristics. Male smallmouth bass from all sites sampled had immature eggs in their testes; prevalence was lowest in the Ohio drainage, intermediate in the Delaware and highest in the Susquehanna. While these findings were disturbing in and of themselves, the study was also able to draw a connection to the increased presence of intersex characteristics and areas of high agricultural use. “The prevalence and severity of the immature eggs in smallmouth bass corresponded with the percent of agricultural land use in the watershed above the collection […]

(Beyond Pesticides, July 2, 2014) According to a new study, few obstetricians offer their pregnant  patients advice on how to avoid environmental toxins that might harm their babies, even though doctors recognize that exposure to chemicals like pesticides, bisphenol-A (BPA), and metals can affect  a pregnancy. The study recommends that the medical community improve medical education and training, develop recommendations for prevention and less toxic alternatives, as well as lend support to policy change. The first of its kind study of prenatal counselling, published in the journal  PLOS ONE, Counseling Patients on Preventing Prenatal Environmental Exposures – A Mixed-Methods Study of Obstetricians, found that U.S. obstetricians and gynaecologists feel they lack the medical education and training, and evidence-based guidelines and tools for communicating potential environmental risks to patients. Exposure to environmental toxins, the researchers from the University of California, San Francisco (UCSF) found, is rarely discussed with pregnant patients, even though a national survey shows that 80 percent of physicians agree they should play a part in reducing patients’ exposure to toxins. But, of the 2,500 respondents, only one in five routinely asked  their  patients about these exposures, and just one in 15 said they received training on the harmful […]

(Beyond Pesticides, April, 29, 2014) According to a recent study published in the American Chemical Society’s (ACS) journal Chemical Research in Toxicology, the chemicals triclosan and octylphenol are linked to the growth of breast cancer cells. Triclosan is an antibacterial and antifungal agent found in numerous commonly known household products. Octylphenol is a commercial solvent that can be found in paints and plastics, and is often used as an inert ingredient in pesticide formulations. Researchers investigated whether these two endocrine-disrupting chemicals (ECDs) contributed to the growth of cancer cells. In their study, Progression of Breast Cancer Cells Was Enhanced by Endocrine-Disrupting Chemicals, Triclosan and Octylphenol, via an Estrogen Receptor-Dependent Signaling Pathway in Cellular and Mouse Xenograft Models, scientists performed both in vitro tests on human breast cancer cells in petri dishes, and in vivo tests via tissue grafts on mice. “Although the doses of EDCs were somewhat high, we did this to simulate their effects of daily exposure, as well as body accumulation due to long-term exposure, simultaneously in animal experiments,” said Kyung-Chul Choi, PhD, co-author of the research. Results of the study established that both triclosan and octylphenol interfered with the genes involved in breast cancer growth. In human […]

(Beyond Pesticides, April 22, 2014) As we reflect on the beauty and wonder of the natural world this Earth Day and seek to restore  and preserve  the intricate web of life on the planet, we face an urgent need to stop ongoing toxic chemical contamination.  The hard truth of our time is that the natural world on which life depends  is under grave threat from numerous toxic insults resulting from mechanized and industrial human activity. Massive die-offs of beneficial organisms, increased rates of autoimmune diseases, endocrine disrupting and transgenerational chemical effects, and widespread pollution of our air and waterways —all linked to pesticides and other toxic chemicals, establish the critical  need  to adopt organic standards in sync with ecosystems. This Earth Day we ask you to spread awareness of toxic chemicals that pollute the environment. Get active to safeguard your community and the surrounding environment from toxic insults: teach your neighbors how to maintain their land without toxic pesticides, protect honeybees from neonicotinoids insecticides, aquatic species from endocrine disrupting chemicals, and the streams, lakes, and rivers we all depend on from the widespread use of harmful synthetic pesticides and fertilizers. Beyond Pesticides has the tools needed to increase environmental awareness […]

(Beyond Pesticides, March 21, 2014) Banned pesticides and flame retardants may be the cause of higher autistic behaviors for children who were exposed in utero, according to new research published last week in the journal Environmental Health Perspectives. Previous research has demonstrated that organochlorine chemicals are linked to learning problems, such as attention-deficit hyperactivity disorder (ADHD), especially in boys. This research is one of the first studies to evaluate their contribution to autistic behaviors. According to the study, Gestational Exposure to Endocrine-Disrupting Chemicals and Reciprocal Social, Repetitive, and Stereotypic Behaviors in 4- and 5-Year Old Children, children who were exposed to higher levels of brominated flame retardant PBDE-28 and trans-nonachlor, a component of the banned pesticide chlordane, scored higher in terms of autistic behavioral patterns as ranked by their mothers. In the study, researchers conducted a case-cohort study recruiting 175 pregnant women from seven prenatal clinics within the greater Cincinnati, Ohio region who provided urine and blood samples during pregnancy to measure the concentration of endocrine disrupting chemicals. On average, pregnant women had 44 suspected hormone disrupting chemicals. Five years later, when children had turned four or five, mothers were asked to rank their children’s behavior based on a series […]

(Beyond Pesticides, March 13, 2014) Part deux of a 2012 study finding that sperm counts in French men had decreased 30% over the past 16 years came to a second startling conclusion in a 2014 analysis: the cause for those dramatic decreases may be pesticides. 2012 Sperm-Count Study Published in the scientific journal Human Reproduction, the landmark 2012 study showed an alarming 30 percent decrease in sperm counts across France between 1989 and 2005. Because the data for the 2012 study were drawn from Fivnat ””a French assisted reproduction technology database”” researches made sure to limit analysis to 26,600 sperm samples from otherwise virile 35-year-old men whose partners’ fallopian tubes were either blocked or missing. This control was added to ensure that the each couple’s infertility was due to these latter problems and not a problem with the man’s sperm. Broken down, the 2012 studies identified a 1.9 percent continued annual dip in sperm concentration and also found that there was a significant 33.4% decrease in the percentage of normally formed sperm over the entire 16-year period. At the time of release, the 2012 study’s authors wrote: “To our knowledge, it is the first study concluding a severe and general […]

(Beyond Pesticides, February 5, 2014) According to a new study published in Environmental Health Perspectives, chemical contaminants in waterways that mimic estrogen -endocrine disruptors- target developing heart valves in fish and impair the growth of fish hearts. The study illustrates that these hormone-mimicking compounds, which include some pesticides, pharmaceuticals, and other household chemicals often found in sewage effluent and runoff that flows into waterways, are being linked to mounting science that show serious human and environmental adverse effects. Researchers from the Fish Health Branch of the U.S. Geological Survey (USGS) and the Carnegie Institution for Science exposed zebrafish embryos to water from 19 sites in the Susquehanna, Delaware, Allegheny and Shenandoah watersheds. Water from 16 of the sites triggered proteins in the fish that were estrogen receptors, indicating that the rivers contained endocrine disrupting chemicals. These receptors are attached to DNA, which turn genes on and off. While such activity is common in the liver, this is the first experiment to show estrogenic activity in heart valves. “This tells us that endocrine-disrupting chemicals could lead to improper heart development. We were quite surprised, since this is something that others hadn’t observed before,” said study co-author Luke Iwanowicz, PhD, and research […]

(Beyond Pesticides, December 17, 2013) A new rule proposed by the U.S. Food and Drug Administration (FDA) requires manufacturers of antibacterial hand soaps, body washes, and other consumer goods to prove that their products are both safe for long-term use and more effective than regular bar soap in order to remain on the market. This announcement, though long-delayed, represents a positive step towards reining in the unnecessary use of antibacterial chemicals at a time when top-level government scientists at the U.S. Centers for Disease Control and Prevention (CDC) have asserted that we’ve reached “the end of antibiotics.”  With the publication of its article The Ubiquitous Triclosan: A common antibacterial agent exposed  in 2004, Beyond Pesticides began a campaign to ban triclosan because of it cross resistance with antibiotics, endocrine disrupting effects, and lack of benefits. “Numerous studies have shown that antibacterial soaps cause more harm than any of their perceived benefits,” said Nichelle Harriott, staff scientist  at Beyond Pesticides. “For the protection of human health and the environment, we urge the FDA to move quickly to get these products off of the market.” FDA’s new rule, announced Monday, will be open for public comment for 180 days and manufacturers will […]

(Beyond Pesticides, November 7, 2013) A study released this week established a strong connection between endometriosis and exposure to two dangerous pesticides: lindane and mirex. While the results are not surprising given past connections between these pesticides and their endocrine-disrupting effects, this new study, Organochlorine Pesticides and Risk of Endometriosis: Findings from a Population-Based Case-Control Study, is one of the first to examine the association between organochlorine pesticides (OCPs) and endometriosis, one of the most common gynecological diseases, in women in the general population. The study’s authors, Kristen Upson, Ph.D. et al,  explained to Environmental Health Perspectives, “Our study suggests that exposure from extensive past use of environmentally persistent OCPs in the United States, or present use in other countries may impact the health of the current generation of reproductive-age women with regard to a hormonally-mediated disease.” In conducting the study, researchers selected a group of women with surgically-confirmed cases of endometriosis from the greater Pacific Northwest area. This group of women was then divided into four groups, based on the level of pesticide in each woman’s blood. Women in the second-highest exposure group for beta-hexacyclochlorohexane (beta-HCH), a byproduct of lindane, had a 70 percent greater risk of endometriosis than […]

(Beyond Pesticides, June 28, 2013) The U.S. Environmental Protection Agency (EPA) released a draft “State of the Science” report last week acknowledging that low dose responses “do occur in biological systems” while defending its current risk assessment procedures as adequate for evaluating low dose effects. This report comes after EPA’s long running failure to fully implement a 1996 Congressionally mandated program to evaluate endocrine disruptors, and heavy criticism last year from prominent scientists who said EPA’s testing procedures are outdated. In 1999 the Natural Resources Defense Council (NRDC) filed a lawsuit against the EPA for failing to meet a statutory deadline for implementation of the Endocrine Disruptor Screening Program (EDSP) required under the 1996 Food Quality Protection Act, forcing the EPA to make a settlement agreement. As a result of  NRDC et al. v. EPA (No. C-99-03701 CAL) filed in the Northern District of California, EPA agreed to start requiring screening and testing of certain chemicals varying by date, using a tiered system. EPA’s two-tiered screening and testing system, requires that EPA will identify which chemicals are able to interact with the endocrine system in Tier 1. Tier 2 screening process was designed to go one step further, requiring EPA […]