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Federal Legislation Introduced to Protect Children from Toxic Pesticide Use at Schools; New Study Documents State Progress in the Adoption of Safer School Pest Management Policies

Wednesday, December 2nd, 2009

(Beyond Pesticides, December 2, 2009) Cancer causing pesticides ”¦ endocrine disruptors ”¦ pesticides linked to neurological and immune system problems ”¦ asthma and learning disabilities. Federal legislation, the School Environment Protection Act of 2009, was introduced yesterday in Congress to protect children from toxic pesticides and pest problems with safer alternatives. The sponsors seek to end unnecessary toxic pesticide use in the nation’s schools, replacing it with safe management techniques and products. When children attend school, it is assumed that they are going to a safe environment, free of toxic chemicals that could harm them. New legislation seeks to make this assumption a reality. With the introduction of the School Environment Protection Act of 2009 (SEPA), H.R. 4159, members of Congress and public health, school employee, children’s health and environmental groups are saying that it is time to stop the unnecessary use of dangerous chemicals and assist schools in the adoption of safer strategies to prevent and manage pest problems. U.S. Representative Rush Holt and 14 of his colleagues put the legislation forward with the foundation of more than a decade of state and local school pest management and pesticide use policies and on-the-ground experience from across the country. SEPA […]

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White House Orders EPA to Move on Endocrine Disrupting Pesticides without Data; EPA Seeks Approval of Guidelines

Wednesday, October 21st, 2009

(Beyond Pesticides, October 21, 2009) The U.S. Environmental Protection Agency (EPA) is making available the battery of scientific assays and test guidelines for conducting the assays for each of 67 chemicals included for Tier 1 testing for endocrine disrupting effects during the next three months. This comes after the Office of Management and Budget (OMB) instructed EPA to use existing toxicity data rather than require companies to conduct new tests to determine whether chemicals can damage the human endocrine system. With the availability of the assays and test guidelines, EPA will move forward with issuing test orders to manufacturers to compel the generation of the needed data. However, acquisition of new, relevant data may be limited. This is because after EPA submitted the request for additional information for OMB approval, the Office issued a directive that approved EPA’s request to collect additional data for the 67 chemicals but warned the agency that it should “to the greatest extent possible” accept existing data to satisfy test requirements. The OMB directive, which observers say contains unusually strong language, is being hailed by industry groups that had been concerned about the prospects for expensive testing mandates. But many environmental groups and scientists say […]

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Groups Petition to Suspend Sewage Sludge Distribution

Wednesday, September 30th, 2009

(Beyond Pesticides, September 30, 2009) The Center the Food Safety and the Resource Institute for Low Entropy Systems have petitioned the City of San Francisco and the San Francisco Public Utilities Commission (SFPUC) to immediately suspend the SFPUC’s Compost Giveaway program because the compost is made with sewage sludge which contains toxic chemicals and hazardous materials. The petition, submitted last Wednesday, cites that the distribution of contaminated compost will spread toxic sludge to homeowners’ backyards, increasing the risk of health problems to children and the community. The SFPUC’s compost giveaway program distributes free compost as part of the commission’s recycling efforts to community gardens, school gardens and local residents. The compost is made of sewage sludge, derived as a by-product of wastewater and sewage treatment, and contains heavy metals, pathogens, pharmaceuticals, PCB’s, flame retardants and endocrine disruptors, such as the antibacterial triclosan. “San Franciscans may think they’re getting a gift from the city, but this is no gift. City residents could be at serious risk of poisoning from the application of sewage sludge to local crops and gardens,” said Paige Tomaselli, staff attorney for the Center for Food Safety. “With this petition, we’re strongly urging the Mayor to put an […]

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Children Living Near Agricultural Pesticide Use Have Higher Cancer Rate

Tuesday, September 29th, 2009

(Beyond Pesticides, September 29, 2009) A new study reveals that children exposed to agricultural pesticides applied near their home have up to twice the risk of developing the most common form of childhood leukemia, according to the Northern California Cancer Center (NCCC). The study, “Residential proximity to agricultural pesticide applications and childhood acute lymphoblastic leukemia,” published in the October issue of Environmental Research, used a unique California database to reveal an elevated risk in acute lymphoblastic leukemia (ALL) among children living near applications of certain categories of pesticides used in agriculture. The study, led by Rudolph Rull, Ph.D., shows an elevated risk of ALL associated with moderate exposure, but not high exposure, to pesticides classified as organophosphates (odds ratio (OR) 1.6), chlorophenoxy herbicides (OR 2.0), and triazines (OR 1.9), and with agricultural pesticides used as insecticides (OR 1.5) or fumigants (OR 1.7). California is one of the few states in the country that requires active reporting of pesticide applications, including time, place, and the type and amount of pesticide used. For this study, researchers were able to link children’s entire residential histories from birth to the time of case diagnosis to this pesticide-use reporting database and identify agricultural pesticides that […]

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U.S. Geological Survey Identifies Intersex Fish Nationwide

Friday, September 18th, 2009

(Beyond Pesticides, September 18, 2009) Previously documented in the Potomac River, which flows through downtown Washington, DC, the occurrence of “intersex” fish is now found to be nationwide. U.S. Geological Survey (USGS) researchers published their study, “Widespread occurrence of intersex in black basses from U.S. rivers” in the online edition of Aquatic Toxicology. USGS researchers examined 16 different species of fish across the U.S. between 1995 and 2004. The condition of intersex fish, male fish producing eggs, is most commonly found in smallmouth and largemouth bass. One third of male smallmouth bass and one fifth of the male largemouth bass are intersex. Scientists tested sites in the Apalachicola, Colorado, Columbia, Mobile, Mississippi, Pee Dee, Rio Grande, Savannah, and Yukon River basins. Research shows intersex fish in approximately one-third of all examined sites. The only site where researchers found no intersex fish is the Yukon River basin. While the study did not look for the causes for intersex fish, scientists believe endocrine disruptors, chemicals that interfere with the body’s hormonal systems, are certainly to blame. “We know that endocrine-active compounds have been associated with intersex in fish, but we lack information on which fish species are most sensitive to such compounds, […]

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Report Finds Inadequate EPA Regulation of Pesticides in Water

Wednesday, August 26th, 2009

(Beyond Pesticides, August 26, 2009) The commonly used herbicide atrazine can spike at extremely high levels which go undetected by regular monitoring, according to new report by the Natural Resources Defense Council (NRDC), Poisoning the Well. Currently, the U.S. Environmental Protection Agency (EPA) considers an annual average atrazine level of below 3 parts per billion to be acceptable for human consumption, although studies have shown adverse health impacts below EPA’s “safe” levels. The analysis by NRDC discovered that in the 139 municipal water systems from which EPA collected data on a biweekly basis in 2003 and 2004, atrazine is found 90% of the time. Furthermore, 54 of these water systems have at least one spike above 3 parts per billion. “The data shows that EPA is unable to adequately regulate atrazine and protect the public from this hazardous herbicide in our drinking water,” said Jay Feldman, executive director of Beyond Pesticides. “With studies showing hormonal and other adverse effects at extremely low levels, any level of atrazine in our drinking water is dangerous and spikes above EPA’s 3 ppb threshold are completely unacceptable. EPA must put public health first and ban this toxic chemical.” Under the federal Safe Drinking Water […]

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Report Implicates Pesticides in Chesapeake Bay’s Decline

Friday, July 31st, 2009

(Beyond Pesticides, July 31, 2009) A group of advocates and experts is warning that pesticide pollution from farm fields and households is contributing to the Chesapeake Bay’s decline, and may well be linked to declines in frogs across the region and intersex fish seen in the Potomac River. In a report released yesterday, the group calls on federal, state and local government to accelerate research into what threats pesticide contamination may pose to the bay, and to step up efforts to reduce such toxic pollution. “The thing that alarms us the most are the endocrine disruptors and the findings that have come out about intersex fish and frogs with reproductive problems,” said Robert SanGeorge, director of the Pesticides and the Chesapeake Bay Watershed Project. Endocrine disruptors are chemicals that mimic the natural hormones in humans or animals and can disrupt their growth and reproduction. The project is a partnership between the Maryland Pesticides Network and the Johns Hopkins Center for a Livable Future. The group’s warning and recommendations are the product of a two-year study, in consultation with scientists, public health experts, government officials, watermen, environmentalists, farmers and pest management industries. The report comes as federal and state governments attempt […]

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Urban Insecticide Use Linked to Decline of Delta Ecosystem

Friday, July 17th, 2009

(Beyond Pesticides, July 17, 2009) High levels of pyrethroid pesticides in the Sacramento-San Joaquin River Delta, the number one river system on America’s Most Endangered Rivers List of 2009, has been linked to heavy urbanization in the region. Leading a study to understand the collapse of the delta’s ecosystem, University of California-Berkeley toxicologist Donald Weston, Ph.D. found that these pesticides most likely reached the river from urban storm drains, collecting household pesticide disposal and runoff from lawns of 1.4 million residents in the Sacramento region. Five years ago, a study by Dr. Weston and his colleague Michael J. Lydy, Ph.D of Southern Illinois University in Carbondale found that synthetic phyrethroids were collecting in river and creek sediments at levels that are toxic to bottom dwelling fish. Current research holds that there are enough pyrethroids to kill tiny shrimp, which are said to be the first link in the aquatic food chain. Pyrethroids are synthetic versions of pyrethrin, a natural insecticide found in certain species of chrysanthemum. It initially came on the market as a ”˜safer’ alternative to the heavily regulated and highly toxic organophosphates, such as diazinon and chlorypyrifos. Despite the fact that there are plenty of effective pest control […]

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Lawsuit to Challenge EPA for Pesticide Impacts on Polar Bears

Friday, July 10th, 2009

(Beyond Pesticides, July 10, 2009) The Center for Biological Diversity notified the U.S. Environmental Protection Agency (EPA) earlier this week of its intent to file suit against the agency for failing to consider impacts to the polar bear and its Arctic habitat from toxic contamination resulting from pesticide use in the U.S. Pesticides registered by EPA for use in the U.S. are known to be transported to the Arctic via various atmospheric, oceanic, and biotic pathways. Such pesticides are biomagnified with each step higher in the food web, reaching some of their greatest concentrations in polar bears, the apex predators of the Arctic. A body of literature demonstrates the far-reaching effects of commonly used pesticides that are suspected endocrine disruptors and persistent organic pollutants, such as atrazine, 2,4-D, lindane, endosulfan, and permethrin, on global ecosystems. These pesticides, among others, and related contaminants have been linked to suppressed immune function, endocrine disruption, abnormalities in reproductive organs, hermaphroditism, and increased cub mortality in polar bears. Human subsistence hunters in the Arctic, who share the top spot on the food web with the polar bear, also face increased risks from exposure to these contaminants. “The poisoning of the Arctic is a silent crisis […]

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EPA Proposes Pesticides Restrictions in Endangered Species Settlement

Monday, July 6th, 2009

(Beyond Pesticides, July 6, 2009) Last week, the U.S. Environmental Protection Agency (EPA) proposed to formally evaluate the harmful effects of 74 pesticides on 11 endangered and threatened species in the San Francisco Bay Area over the next five years, and to impose interim restrictions on use of these pesticides in and adjacent to endangered species habitats. The proposal stems from a settlement agreement with the Center for Biological Diversity, which sued EPA in 2007 for violating the Endangered Species Act by registering and allowing the use of toxic pesticides in Bay Area endangered species habitats without determining whether the chemicals jeopardize those species’ existence. “Tens of millions of pounds of toxic and poisonous chemicals, known to be deadly to endangered species and harmful to human health, including proven carcinogens and endocrine disruptors, are applied in the Bay Area each year, and many of those find their way through runoff or drift into our soil, creeks and rivers, San Francisco Bay, and sensitive wildlife habitats,” said Jeff Miller, conservation advocate with the Center. “The toxic stew of pesticides in the Bay-Delta has played a major role in the collapse of native fish populations, and pesticides are a leading cause of […]

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Two States Pass Bills on Lawn Pesticides Use at Day Care Centers

Thursday, May 21st, 2009

(Beyond Pesticides, May 21, 2009) The Connecticut and Illinois legislatures have passed bills increase the protection of children at day care centers from toxic lawn chemicals. While providing different degrees of protection, both bills, which build on their existing state school pesticide laws, passed with overwhelming support in both chambers of their General Assembly. The bills passed both legislatures on unanimous votes with the exceptiion of five dissenting votes in the Connecticut House of Representatives. Connecticut State Representative Terrie Wood said, “We know that contact with pesticides and chemicals are not compatible with healthy living. It is time to err on the side of caution and ban these pesticides from use any place our children and grandchildren learn and play.” The Connecticut bill, Pesticide Applications at Child Day Care Centers and Schools, extends the states’ existing law that prohibits the application of pesticides on kindergarten through 8th grade schools’ grounds to include day care center grounds as well. In addition, the bill requires only licensed pest control operators apply pesticides in day care center facilities or on their grounds. There is an exemption that allows general use pesticides to be used in an emergency situation when a pest, such as […]

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Noted Scientist Says EPA Tests for Endocrine Disruption Outdated

Wednesday, April 29th, 2009

(Beyond Pesticides, April 29, 2009) The U.S. Environmental Protection Agency (EPA) announced earlier this month that it is finally ready to move forward with preliminary testing of 67 active and inert pesticide ingredients for possible endocrine disrupting effects. But, according to prominent researcher and author Theo Colborn, PhD, these tests are outdated, insensitive, crude, and narrowly limited, and will fail to detect many serious effects on human development. In an eye-opening opinion-editorial published in Environmental Health News, Dr. Colborn, founder and president of The Endocrine Disruption Exchange, and Co-author of Stolen Future, says that EPA’s testing protocol is “a pitiful skeleton” of what it needs to be. The tests to be used by EPA were first recommended in 1998. Since then the science has made progress and become more sophisticated. Current research is based on different assumptions than the toxicological assumptions that first drove the EPA test designs. However, EPA has not updated its protocol. Each of EPA’s tests and assays was designed under the surveillance of corporate lawyers who had bottom lines to protect and assorted toxicologists who were not trained in endocrinology and developmental biology. For over a decade, EPA ignored the vast wealth of information on endocrine […]

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Celebrate National Healthy Schools Day, Stop Hazardous Pesticide Use at Schools

Monday, April 27th, 2009

(Beyond Pesticides, April 27, 2009) Spurred by widespread concerns about children’s environmental health in schools, an array of government entities and child health advocates are celebrating National Healthy Schools Day today with nearly forty activities planned in twenty-one states and Canada. National Healthy Schools Day, coordinated by the Healthy Schools Network, is a day to promote and celebrate healthy school environments that are conducive to learning and protect occupant health. Beyond Pesticides, a co-sponsor of National Healthy Schools Day, asks schools to immediately stop using hazardous pesticides in school buildings and on school grounds and use alternative, non-toxic methods for preventing and managing pests. “We’re proud to join so many dedicated partners in sponsoring National Healthy Schools Day,” said Lisa Jackson, U.S. EPA Administrator. “EPA’s mission is to protect the American public where they live, work and play — and that certainly includes protecting children where they learn. Our nation’s children, parents, and educators deserve to know that their schools provide a safe and healthy environment. We encourage everyone concerned about healthy schools to use National Healthy Schools Day as a spring board to improve our school environment both indoors and out.” The vulnerability of infants and children to the […]

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EPA Identifies Pesticides To Be Sceened for Endocrine Disruption

Friday, April 17th, 2009

(Beyond Pesticides, April 17, 2009) Thirteen years after the Food Quality Protection Act (FQPA) ordered EPA to develop a screening process for endocrine disrupting chemicals, the Environmental Protection Agency (EPA) has released a final list of chemicals to be included in Tier 1 testing for endocrine disrupting effects of pesticides in use. While the list has been reduced from the 73 chemicals announced two years ago, trials will begin this summer to determine human risk from some of the chemicals to which we are most commonly exposed. “Endocrine disruptors can cause lifelong health problems, especially for children,” stated EPA Administrator Lisa Jackson. “Gathering this information will help us work with communities and industry to protect Americans from harmful exposure.” EPA’s recent announcement of these chemicals can be found on EPA’s Endocrine Disruptor Screening Program (EDSP) page. According to EPA, “The Agency deleted 6 chemicals from the draft list of 73 based upon recent information showing that the chemicals are no longer expected to be found in 3 exposure pathways.” To be included on the initial list, EPA established that chemicals need to be found in three of EPA’s four exposure pathways: food, drinking water, residential use, and occupational exposure. Azinphos-methyl […]

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European Union Completes 16-Year Review of Pesticides

Friday, March 20th, 2009

(Beyond Pesticides, March 20, 2009) On March 12, the European Commission said it made an important step forward in its efforts to ensure improved protection of human health and the environment, as it completed the review of existing pesticides that were on the market before 1993. This program concerned about 1,000 substances contained in tens of thousands of products that were on the market in 1993. All reviewed pesticides have undergone a detailed risk evaluation with respect to their effects on humans and on the environment. The review is a joint effort by the Commission, the European Food Safety Authority (EFSA) and the EU Member States. EU Health Commissioner Androulla Vassiliou said: “Today represents a milestone in our effort to ensure improved protection of human health and the environment. The review of existing pesticides has lead to the removal from the market of more than two thirds of these substances. I can now say with confidence that our food has become greener.” Council Directive 91/414/EEC lays down a comprehensive risk assessment and authorization procedure for active substances and products containing these substances. Each active substance was evaluated as to whether it could be used safely with respect to human health […]

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Virginia Legislature Passes Voluntary School Pest Management Bill

Monday, March 9th, 2009

(Beyond Pesticides, March 9, 2009) In the waning days of the 2009 legislative session, the Virginia General Assembly unanimously passed a weakened school Integrated Pest Management (IPM) bill that creates a statewide, voluntary school pest management program. While the law will increase public awareness of the antiquated practice of routine pesticide applications at school facilities, it does not mandate a change in practices. The legislation provides information to school districts on IPM that “minimizes the use of pesticides and the risk to human health and the environment associated with pesticide applications.” Beyond Pesticides advocates pesticide use reduction and elimination strategies and only the use of “least-toxic” pesticides as a last resort. Experience shows that school pest management must emphasize pest prevention and management strategies that exclude pests from the school facility through habitat modification, entry way closures, structural repairs, sanitation practices, natural organic management of playing fields and landscapes, other non-chemical, mechanical and biological methods, and the use of the least-toxic pesticides only as a last resort. School is a place where children need a healthy body and a clear head in order to learn. Children are especially sensitive to pesticide exposures as they take in more pesticides relative to […]

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Transforming Pesticide Policy: Sign-on to Priorities for Obama Administration

Tuesday, January 27th, 2009

Transforming Government’s Approach to Regulating Pesticides to Protect Public Health and the Environment is a document drafted by Beyond Pesticides and Pesticide Action Network North America that captures grassroots pesticide priorities for the Obama Administration. While we have already submitted these priorities to the Obama transition team, we ask for your support and suggestions because we will continue to use this document as we begin to work with the new administration. To sign on to the document, follow the link above and include your name, organization/company affiliation (if any), city and state in the comment field. The document identifies what the Obama administration can/should take on under existing authority/statutory responsibility, with a specific focus on the first 100 days. Most of the comments in our document focus on pending regulatory actions and pending petitions before the government, either because of ongoing chemical reviews, pending rulemaking, or petitions. While we incorporate big picture thinking, we are focused on specific actions that the relevant agencies could take now. We plan to meet and communicate with the Obama administration to put these suggested actions in place. Issues covered in the document include, but are not limited to: Promoting organic agriculture; Protecting sensitive species; […]

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Pyrethroid Pesticides Found in Homes and Daycare Centers

Monday, November 3rd, 2008

(Beyond Pesticides, November 3, 2008) A new study, Pyrethroid pesticides and their metabolites in vacuum cleaner dust collected from homes and day-care centers (doi:10.1016/j.envres.2008.07.022), by the U.S. Environmental Protection Agency’s (EPA) National Exposure Research Laboratory finds concentrations of 13 synthetic pyrethroids and their degradates in indoor dust collected from homes and childcare centers in North Carolina and Ohio. The study results show the extent to which hazardous pesticides are present in indoor environments and threaten the public’s health, especially the health of children. With 85 vacuum cleaner bags analyzed, permethrin was present in all 85 dust samples, at least one pyrethroid pesticide was found in 69 samples and phenothrin was found in 36 samples. According to the study findings published in the November issue of the journal Environmental Research, the median concentration of permethrin in the samples is 1454ng/g of dust. Excluding permethrin, pyrethroid conectrations are less than or equal to 100ng/g of dust. The majority of the metabolites are present in more than half of the dust samples. This is not the first time researchers have found pesticides in dust in homes. A study published in the International Journal of Hygiene and Environmental Health (208: 193-199) also found that […]

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Maryland Health and Elder Care Facilities Lead Way In Cutting Toxic Chemical Use

Friday, October 24th, 2008

(Beyond Pesticides, October 24, 2008) A report to be released October 27 by public health groups and leading Maryland health and elder care facilities documents new practices and policies to eliminate toxic pesticide use. The changes reflect a heightened awareness of the need to protect particularly vulnerable populations from serious health risks associated with toxic chemical exposure. A growing body of scientific research links pesticides to Parkinson’s disease, asthma, cancer and other illnesses. “The Maryland health care institutions in the report are to be commended for showing national leadership in adopting non-toxic pest management techniques that protect the health of patients, visitors and staff,” said Jay Feldman, the report’s co-author and executive director of Beyond Pesticides. The report, “Taking Toxics out of Maryland’s Health Care Sector: Transition to Green Pest Management Practices to Protect Health and the Environment,” was co-written by the Maryland Pesticide Network, a statewide coalition advocating safe pest management practices, and Beyond Pesticides, a national environmental and public health group, under their joint “Integrated Pest Management (IPM) in Health Care Facilities Project,” and in collaboration with Maryland Hospitals for a Healthy Environment at the University of Maryland School of Nursing. IPM is an approach to pest management […]

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Proposed European Pesticide Ban Under Attack

Wednesday, August 27th, 2008

(Beyond Pesticides, August 27, 2008) Citing the possibility of lower crop yields and higher food prices, government ministers in the United Kingdom are planning to step up pressure on the European Parliament in opposition to plans to ban the most hazardous pesticides, amounting to three quarters of the pesticides used by farmers in the European Union. Environmental campaigners, like the UK Pesticides Campaign, are adamant that a crackdown on the use of pesticides is needed to protect public health and believe that the new measures must not be watered down by industry lobbying. Officials from the U.K. Department of the Environment, Food and Rural Affairs (DEFRA) believe that the ban would remove important pesticides from the market. Those arguing against the proposal say it could prevent the use of certain fungicides and result in substantially lower wheat yields, postulating a 30 percent reduction from current levels. DEFRA officials claim that the ban would have “significant adverse impact on crop protection, but secure no significant health benefits for consumers.” British Farming Minister Lord Rooker is adamant that fungicides should not be banned before alternatives are approved and is urging other European countries to block the measure. The controversy centers on the […]

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Congress Agrees to Ban Toxic Chemicals in Children’s Toys

Wednesday, July 30th, 2008

(Beyond Pesticides, July 29, 2008) After repeated calls from parents, consumer groups and health experts to protect children from toxic chemicals, congressional lawmakers have agreed on statutory language that would prohibit the use of a family of toxic chemicals found in many children’s products, according to the Washington Post. Legislators are proposing to include this language to the Consumer Product Safety Commission Reform Act (HR 4040 and S.2663). This new ban, set to take effect in six months, will have far reaching implications on the long-debated overhaul of U.S. consumer safety standards. On Monday, House and Senate lawmakers agreed to prohibit three types of phthalates from children’s toys and to outlaw three other phthalates from products pending an extensive study of their health effects in children and pregnant women. This measure aims to improve product safety and is part of popular legislation to reform the Consumer Product Safety Commission, which oversees more than 15,000 types of products. Phthalates are used to soften plastic and are found in homes across the U.S. in a wide range of products including shower curtains, shampoos, perfumes, toys and pesticides, to name a few. They are associated with adverse developmental and reproductive health effects, including […]

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In Agricultural Areas, Male Toads Feminized

Thursday, July 17th, 2008

(Beyond Pesticides, July 17, 2008) In a new study published in Environmental Health Perspectives, researchers have found an increased occurrence of intersex toads in areas with greater agricultural land cover. This points to a link between certain pesticides and endocrine disruption, a change in the hormonal balance that can have sexual and reproductive effects. Such results implicate pesticides in the decline of amphibian populations, and suggests that these chemicals are also adversely affecting humans. The study, which was conducted in south Florida, looked at cane toads, Bufo marinus, at five sites with differing land use patterns ranging from suburban to nearly completely agricultural (primarily sugarcane and vegetables). Researchers examined physical characteristics such as coloration, sexual organs, and forelimb length, as well as hormone concentrations, and found a higher rate of feminization for toads in agricultural areas. In these areas, glyphosate (the active ingredient in Round Up herbicide) and atrazine (an herbicide) use is common. Tyrone Hayes, PhD, was one of the first to document the endocrine disrupting effects of atrazine on frogs in a laboratory setting. Countering any doubts of why this work is important, Dr. Hayes said, “People often say, ”˜It is just frogs, so who cares?’ Well it […]

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Study Finds Atrazine Disrupts Human Hormone Activity

Friday, May 30th, 2008

(Beyond Pesticides, May 30, 2008) A recent study has linked the common herbicide atrazine with endocrine disruption in both fish and human cells. Entitled “The Herbicide Atrazine Activates Endocrine Gene Networks via Non-Steroidal NR5A Nuclear Receptors in Fish and Mammalian Cells,” the University of Califonia, San Francisco (UCSF) research examines the reaction of zebrafish to environmentally relevant levels of atrazine, and mirrors the study in human placental cells. The zebrafish, which are particularly sensitive to endocrine disruptors,  are “feminized”  in greater proportion than the unexposed control group. Fish exposed to atrazine for 48 hours at levels found in agricultural runoff produced twice as many female fish as male. “These fish are very sensitive to endocrine disrupting chemicals, so one might think of them as ‘sentinels’ to potential developmental dangers in humans,” said senior author Holly Ingraham, PhD. “These atrazine-sensitive genes are central to normal reproduction and are found in steroid producing tissues. You have to wonder about the long-term effects of exposing the rapidly developing fetus to atrazine or other endocrine disruptors.” In human cell studies, the researchers found that atrazine activates genes involved in hormone signally and steroid synthesis. “Endocrine-related cell types with a capacity for steroid generation appear […]

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