(Beyond Pesticides, August 25, 2022) A study published in World Journal of Pediatrics finds an association between antibiotic and neonicotinoid (neonic) exposure and onset of pediatric (childhood) type 1 diabetes (T1D) through effects on the gut microbiome. Individuals with type 1 diabetes are at higher risk of other autoimmune disorders, including thyroid and celiac disease. Ample evidence demonstrates environmental contaminants like pesticides and antibiotics negatively affect human mouth and gut microbes. Through the gut biome, pesticide exposure can enhance or exacerbate the adverse effects of additional environmental toxicants on the body. Moreover, studies find low levels of pesticide exposure during pregnancy or childhood cause adverse health effects from metabolic/immune disorders to mental and physical disabilities. Children are particularly vulnerable to the impacts of pesticide exposure as their developing bodies cannot adequately combat exposure effects. Although studies show how chemical exposures affect overall human health, more research is now questioning how these toxic chemicals influence gut health and subsequent occurrence of diseases. In children, gut microbiome disruption, or gut dysbiosis, has significant associations with type 1 diabetes development, and disruption of gut microbiota plays a role in type 2 diabetes development. Over 11 percent (>37 million) of individuals in the U.S. have diabetes, and cases are growing by millions annually. With increasing rates of type 1 and […]

(Beyond Pesticides, August 12, 2022) Gestational (during pregnancy) exposure to endocrine disrupting chemicals (EDCs) like pesticides, per- and polyfluoroalkyl substances (PFAS), among others, may increase pediatric (child) liver injury and non-alcoholic fatty liver disease (NAFLD) risk, according to a study published in Environmental Health. Past studies associate exposure to EDCs with increased susceptibility to adverse health effects during critical fetal and childhood developmental periods. The World Health Organization (WHO), European Union (EU), and endocrine disruptor expert (deceased) Theo Colborn, Ph.D., classify over 55 to 177 chemical compounds as endocrine disruptors, including various household products like detergents, disinfectants, plastics, and pesticides. Endocrine disruption can lead to several health problems, including hormone-related cancer development (i.e., thyroid, breast, ovarian, prostate, testicular), reproductive dysfunction, and diabetes/obesity that can span generations. Because EDCs are ubiquitous because they are found in many products, studies report that these toxic chemical compounds are detectable in infants, children, and pregnant women. Furthermore, pregnant women can readily transfer compounds to the developing fetus through the placenta. Therefore, it is essential to understand the mechanism behind how harmful chemical exposure induces endocrine disruption during critical developmental periods. Researchers note, “Considering the lack of studies on endocrine disruption and pediatric NAFLD, research like this highlights the need to understand the underlying […]

(Beyond Pesticides, August 9, 2022) The most widely used pesticide chemicals in the United States are not listed on product labels, yet pose widespread environmental and public health hazards, according to commentary published this month in Environmental Health Perspectives by two veteran researchers. At issue are adjuvants and so-called “inert” (or “other”) ingredients, chemicals that are added to formulated pesticide products, but do not undergo the same safety reviews as the active ingredient in pesticide products. This donut hole of regulation has permitted, as the commentary shows, millions of pounds of chemicals to be applied in California and throughout the country without proper scientific evaluation of their human health or ecological impact. Researchers first draw a distinction between adjuvant products and inert ingredients in pesticide products. Adjuvants are materials specifically designed to improve the performance of a pesticide spray and are sold separately from formulated pesticide products. Adjuvants are “tank mixed” with a pesticide prior its application. Inert ingredients are any ingredient within a formulated pesticide product that is not designed to prevent, destroy, or repel a pest. Adjuvants and inert ingredients can be the same material – the difference lies in when they are added to a formulated pesticide […]

(Beyond Pesticides, July 21, 2022) Research published in Scientific Reports finds an association between the increasing emergence of nonalcoholic fatty liver disease (NAFLD) and exposure to endocrine (hormone) disrupting chemicals, like organochlorine pesticides (OCPs). It is well-known that traces of legacy (past-use) pesticides, like organochlorines, remain in the environment for decades—possibly centuries, post-final application, as OCPs have greater chemical stability and gradual attenuation. However, these chemicals have profound adverse impacts on human health, especially on the endocrine system. Obesity, insulin resistance, type 2 diabetes, and elevated liver enzyme resulting from endocrine disruption contribute to NAFLD and can lead to liver cirrhosis. Although some, but not all, manufacturing and use of specific OCPs have declined in the U.S., OCPs remain a global issue, as much of the developing world still reports usage. Considering the lack of studies on OCP-induced endocrine disruption and NAFLD, research like this highlights the need to understand the underlying mechanisms that contribute to growing endocrine disease incidents.   The study determined that there is an association between OCP exposure and NAFLD using the fatty liver index (FLI), a predictor of lipid (fat) accumulation in the liver. The researcher collected blood serum to measure the concentration of OCPs, specifically evaluating detectable […]

(Beyond Pesticides, July 18, 2022) The failure of the U.S. Environmental Protection Agency (EPA) to meet its statutory responsibility to protect people and wildlife from the dire consequences of exposure to endocrine disrupting chemicals must end. A study published in Toxicology and Applied Pharmacology adds urgency to the need to eliminate endocrine-disrupting pesticides. The authors find that prepubescent exposure to endocrine-disrupting chemicals (EDCs), including pesticides, impairs male reproduction through the interruption of testicular homeostasis and development of reproductive Leydig cells, and can have multigenerational effects. This adds to the long list of scientific articles showing EPA neglect of the devastating effects of widely used pesticides. Tell EPA that pesticide use cannot continue without findings of no endocrine disruption. Tell Congress to ensure that EPA does its job. More than 50 pesticide active ingredients have been identified as endocrine disruptors that mimic the action of a naturally-produced hormone, such as estrogen or testosterone, thereby setting off similar chemical reactions in the body; block hormone receptors in cells, thereby preventing the action of normal hormones; or affect the synthesis, transport, metabolism and excretion of hormones, thus altering the concentrations of natural hormones. Endocrine disruptors have been linked to attention deficit hyperactivity disorder (ADHD), […]

(Beyond Pesticides, July 14, 2022) A study published in Toxicology and Applied Pharmacology finds prepubescent exposure to endocrine-disrupting chemicals (EDCs), including pesticides, impairs male reproduction through the interruption of testicular homeostasis and development of reproductive Leydig cells. Endocrine disruptors are xenobiotic (i.e., chemical substances like toxic pesticides foreign to an organism or ecosystem). Many reports demonstrate that exposure to endocrine-disrupting chemicals can adversely affect human, animal—and thus environmental—health by altering the natural hormones in the body responsible for conventional reproductive, physical, and mental development. Scientists and health officials already associate pesticide exposure with a decrease in male fertility, including reduced sperm count, quality, and abnormal sperm development. The presence of pesticides in the body has implications for human health, especially during vulnerable life stages, such as childhood, puberty, pregnancy, and old age. Therefore, it is essential to understand how exposure to toxic chemicals in the environment affects future reproductive success and health. The researchers note, “Recent studies revealed that exposures to EDCs during so-called critical windows of susceptibility (prenatal, prepubertal, pubertal, and aging periods) could disrupt healthy patterns of testes development and homeostasis, which can be demonstrated as an impaired testicular function later in life. However, much more work is needed to understand better the cellular […]

(Beyond Pesticides, July 12, 2022) More than four out of five U.S. children and adults over the age of six have detectable levels of glyphosate in their bodies, according to data recently published by the Centers for Disease Control and Prevention (CDC). With strong evidence implicating this chemical as a carcinogen, and emerging data associating it with adverse birth outcomes, the findings raise broad concerns for public health. As the U.S. Environmental Protection Agency (EPA) continues to permit widespread public exposure to toxic chemicals based on obscure economic arguments over the claimed benefits of pesticides, advocates say it is time for a change that embraces health and the environment over the profits of pesticide manufacturers. CDC’s testing data was developed as part of its National Health and Nutrition Examination Survey (NHANES), a long-running program that began in the early 1960s and has since become a continuous program focused on American health and nutrition measurements. Data from this program are subsequently analyzed to help inform the prevalence of disease in the U.S. population and are used to develop public health policies. A total of 2,310 urine samples retained from studies conducted in 2013-2014 were analyzed by NHANES researchers for the presence […]

(Beyond Pesticides, May 5, 2022) A report published in Biological Conservation finds environmental pollutants, including pesticides, pharmaceuticals, plastics, and particulate matter, adversely affect tropical terrestrial wildlife. Specifically, these contaminants can interact with one another, altering the chemical landscape of the ecosystem, and causing changes in the endocrine and microbiome systems of mammals. Since the publication of Rachel Carson’s Silent Spring (1962), global attention to the danger of pesticides has increased, with environmental agencies banning the use of legacy pesticides like organochlorines for their devastating toxic—sometimes lethal—effects. However, these chemicals can remain in the environment for decades and interact with various current-use pesticides, including organophosphates, neonicotinoids, and pyrethroids. Although many studies demonstrate that environmental pollution plays a significant role in premature deaths among humans, there is a lack of research on how environmental pollution directly affects tropical species mortality. Considering human and wildlife habitats tend to overlap, and chemical pollutants can drift from chemically treated areas, wildlife populations are more likely to experience similar health effects. With the number of chemicals in the ecosystem growing, studies like these highlight the need for pesticide policies that protect human health in addition to the integrity of the chemical landscapes accommodating wildlife. The researchers note, “Using […]

(Beyond Pesticides, April 5, 2022) A meta-analysis by the Federal University of Technology – Paraná finds the herbicide 2,4-D causes indiscriminate harm, increasing the mortality rate among exposed animals. The severity of chemical exposure relies on species sensitivity, exposure rate, and lifecycle stage. However, commercial formulations of 2,4-D, commonly used in the environment, prompt a higher species mortality rate than technical (pure) 2,4-D alone. Like many other common herbicides such as glyphosate, 2,4-D has global uses that allow the chemical to accumulate in the environment, including soils, waterways, and tissues of non-target species. Therefore, meta-analyses like this help local and government officials make holistic decisions regarding environmental contaminants that incorporate conclusions from various studies. Using the Web of Science and Scopus databases, researchers compiled various studies (or meta-analyses) on the lethality of 2,4-D in different animal species (e.g., vertebrates, invertebrates). Researchers evaluated each study regarding the mortality rate of control and experimental groups, animal sensitivity to chemical exposure during a specific life stage, chemical formulation (e.g., commercial or technical), and exposure routes causing mortality. The analysis demonstrates that vertebrates experience higher mortality rates from 2,4-D exposure, with fish and birds presenting the highest mortality rate. Regarding life stages, larval and adult […]

(Beyond Pesticides, February 10, 2022) A National Institute of Environmental Health Sciences (NIEHS)-funded study finds that patterns of pesticide exposure among farmers have geographical and temporal significance. Specific use of and exposure to organophosphate and carbamate chemicals decrease enzyme activity within the body, resulting in greater health anomalies among farmers, especially during agricultural seasons. The use of xenobiotic (foreign chemical compounds) substances like pesticides and fertilizers in agriculture are increasing. Thus, those working with and around these toxicants must have protection. Considering that agricultural workers often experience pesticide exposure at higher rates due to occupation, long-term research must identify potential health concerns surrounding common pesticides. The study author, Dana Barr, Ph.D., states, “The majority of farmers in this study reported that they had at least one health symptom associated with pesticide intoxication. This investigation can be used to promote safer use of pesticides among farmers and mitigate exposure among residents living near a rice field. The findings will be critical for establishing and launching several preventive programs in the future.” Researchers evaluated the health effects of pesticide exposure among a cohort of farmers in Thailand during inactive and active rice farming periods. Using geographic information system (GIS) mapping, researchers compared […]

(Beyond Pesticides, February 4, 2022) In January, the U.S. Department of Agriculture (USDA) issued its 30th Pesticide Data Program (PDP) Annual Summary report (which evaluates each year the presence of pesticide residues on produce) and misleads the public on the safety of food and agricultural practices. This 2020 report concludes that more than 99% of the produce samples tested showed residues below established U.S. Environmental Protection Agency (EPA) benchmark levels. At first blush, this sounds very reassuring, but Beyond Pesticides maintains that there is (always) more to the “safety” story, not least of which are serious deficiencies in EPA’s establishment of those “tolerances.” Those flaws include a lack of risk assessment for vulnerable sub-populations, such as farmworkers, people with compromised health, children, and perhaps, cultural/ethnic and regional sub-groups of the general population, and a failure to fully assess serious health outcomes such as disruption of the endocrine system (which contributes to numerous serious diseases). For everyone, Beyond Pesticides recommends choosing organic produce whenever possible — the vast majority of which does not contain synthetic pesticide residues. The PDP report asserts that “the data . . . illustrate that residues found in agricultural products sampled are at levels that do not pose […]

(Beyond Pesticides, January 25, 2022) Research at the University of North Carolina at Chapel Hill identifies how triclosan (TCS), an antimicrobial agent used in many household products, impacts the microbial communities in the gut, causing inflammation. According to the study published in Nature Communications, triclosan worsens the effects of ulcerative colitis, an inflammatory bowel disease (IBD), through the retention of harmful bacteria. Ample evidence demonstrates environmental contaminants, including pesticides like triclosan, negatively affect microbes in the human mouth and gut. Although studies show how triclosan exposure affects human health, more research is now questioning how exposure to these toxic chemical influences gut health. Therefore, studies like these highlight the importance of evaluating how chemical contaminant deregulates normal bodily function through microbiome changes. Furthermore, the study has significant implications for considerations that should be, but are not currently, a part of pesticide review and registration by the U.S. Environmental Protection Agency (EPA). The researchers note, “Together, our results define a mechanism by which intestinal microbes contribute to the metabolic activation and gut toxicity of TCS, and highlight the importance of considering the contributions of the gut microbiota in evaluating the toxic potential of environmental chemicals.” Instances of intestinal bowel disease (IBD)—involving the chronic inflammation […]

(Beyond Pesticides, January 3, 2022) Environmentalists and public health advocates are calling for an aggressive program of policy change in 2022—change they say is critical to addressing existential crises of public health threats, biodiversity collapse, and severe climate disruption that is not being taken seriously by policy makers. On November 23, 2021, Senator Cory Booker introduced legislation to eliminate many of the current problems with the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), which regulates the registration and use of pesticides in the U.S. It corrects some of the worst mistakes in registering pesticides and removes some of the worst loopholes in the law. However, in order to prevent future pesticide problems, we need reform that goes deeper. Urge your Senators to co-sponsor legislation to reform the toxic core of federal pesticide law. Specifically, the bill, the Protect America’s Children from Toxic Pesticides Act of 2021 (PACTPA), would provide some desperately-needed improvements to FIFRA to better protect people and the environment, including: Bans some of the most damaging pesticides scientifically known to cause significant harm to people and the environment: Organophosphate insecticides, which are designed to target the neurological system and have been linked to neurodevelopmental damage in children; Neonicotinoid insecticides, which […]

(Beyond Pesticides, December 9, 2021) The cost to maintain crops using conventional pesticides outweighs the economic benefits from crop production and yield, according to a report, Pesticides ‘cost double the amount they yield,’ by the French-based organization Bureau for the Appraisal of Social Impacts for Citizen Information (BASIC). Moreover, the annual cost of increasing organic farms three-fold by 2030 is less than the cost of pesticides to society (i.e., adverse health and ecological effects from pesticide use and contamination). However, the price to pay from pesticide use encompasses much more than the products themselves. Researchers point to the need for government and health officials to consider the billion-dollar costs associated with adverse health effects from pesticide use, especially as studies confirm that pesticides cause cancer, Parkinson’s, and other diseases that are increasing. Thus, this report adds to the growing body of research demonstrating the unsustainability of conventional, chemical-intensive agricultural practices. The National Academy of Sciences identifies four goals of sustainable agriculture—productivity, economics, environment, and social well-being for future generations. However, current chemical pesticide use threatens sustainable agriculture. Although the primary concerns about pesticide usage centers on health and ecological concerns, including food security, this report provides an economic assessment that offers an […]

(Beyond Pesticides, December 2, 2021) A study published in Cellular Physiology and Biochemistry finds atrazine (ATR) exposure worsens lung disease outcomes in individuals with idiopathic (spontaneous) pulmonary fibrosis (IPF), a group of incurable lung diseases involving damaged/scarred lung tissue. Furthermore, chemotherapeutic products used to treat lymphoma (immune system cell cancer) like bleomycin can induce pulmonary fibrosis complications exacerbated by pesticide exposure. However, pesticide-related pulmonary fibrosis can have implications for neurological health, such as motor function. Scientific literature already finds an association between pesticide exposure and respiratory illnesses such as asthma, lung cancer, and chronic obstructive pulmonary disease (chronic bronchitis). Although IPF impacts over 5 million people a year globally, the disease is difficult to predict, which is concerning as the death rate is 50 to 56 percent within the first few years. Therefore, studies like this highlight the significance of evaluating how pesticide exposure impacts respiratory function, especially when exposure to respiratory toxicants increases vulnerability to existing respiratory-fixated illnesses like Covid-19. Advocate have urged the U.S. Environmental Protection (EPA) to incorporate scientific findings that these—where chemical exposures exacerbate an existing medical condition—into its pesticide registration review program. Researchers note, “[O]ur data represent an addition to the complex information on ATR-induced pulmonary toxicity. In particular, in this […]

(Beyond Pesticides, December 2, 2021) Thousands of residents in Houston, Texas are suing Union Pacific Railroad Company for contaminating their properties with highly hazardous creosote wood preservatives. One of these lawsuits comes from Latonya Payne, legal guardian of Corinthian Giles, a 13-year-old boy who died of leukemia after a five year battle with the disease. A recent report found that the community is in the midst of a childhood leukemia cancer cluster, with disease rates five times the national average. Late last month, U.S. Environmental Protection Agency (EPA) Administrator Michael Regan toured the area as part of his Journey to Justice tour. However, while Administrator Regan vows federal assistance with the cleanup of these long-lived chemicals, EPA is currently in the process of reauthorizing creosote use for another 15 years with the knowledge that it is virtually impossible to produce and use without causing contamination and poisoning. Some environmental advocates are suggesting that Administrator Regan take a tour of EPA’s pesticide registration program and stop the unnecessary poisoning that disproportionately affects people of color and those with vulnerabilities or preexisting medical conditions that increase their vulnerability to toxic chemical exposure. While advocates say that cleaning up EPA’s mess in communities […]

(Beyond Pesticides, December 1, 2021) Women exposed to metabolites of the banned insecticide chlordane are over three times more likely to develop endometriosis, finds research published in the journal Environment International. The study is the latest to find links between persistent organic pollutants (POPs), still lingering in our environment and in our bodies, and chronic disease. According to an economic analysis conducted in 2016, exposure to endocrine (hormone) disrupting chemicals, often implicated in considerable damage to the body’s reproductive system, results in billions of dollars of health care costs from female reproductive disorders. Researchers set out to integrate two methodologies into their evaluation, combining analysis of POP biomarkers in blood with an analysis of biomarkers in that body that correspond with cell functioning, inflammation, and stress. A total of 87 women were enrolled in the study, half of whom had deep endometriosis, a quarter of whom also had the disease and sought surgical intervention, and a remaining quarter without reproductive concerns acted as a control. Twenty polychlorinated biphenyls (PCBs) and 30 organochlorine pesticide compounds were analyzed, as were various biomarkers and inflammatory cytokines. The analysis revealed two compounds to be positively associated with endometriosis – trans-nonachlor, a breakdown product of […]

  (Beyond Pesticides, November 24, 2021) On Thanksgiving, thank you for being a part of Beyond Pesticides and sharing and contributing to the vision necessary to protect the web and fragility of life. We believe that there is no time like Thanksgiving to think about how we can more effectively join together as families and communities across divisions and different points of view to find a common purpose in protecting the health of the environment and all that inhabit it. Unfortunately, there are a host of pesticides, genetically engineered materials, and others in conventional Thanksgiving foods that not only impact human health, but threaten the environment. With far too many adverse health and ecological effects associated with toxic chemicals, organic practices are viable solutions to mitigate pesticide contamination and subsequent exposure. Read on as we consider the range of challenges we must confront, and the solutions that can bring us all together. The Climate As climate impacts grow, an increase in uses of synthetic pesticides in agriculture is likely — because of waning efficacy (pesticide resistance) of these compounds, and mounting pest pressure (i.e., increasing insect population and metabolism). Production of pesticides contributes to greenhouse gas emissions gas (e.g., nitrous […]

(Beyond Pesticides, November 1, 2021) Join with 37 environmental and health groups, farm organizations, and beekeeper councils, who have delivered a letter to the Environmental Protection Agency (EPA) leaders seeking major reforms in the Office of Pesticide Programs (OPP). They provided a comprehensive list of OPP’s major failures as the lead federal office for pesticide regulation and management, including: Allowing chlorpyrifos to stay registered for more than 14 years after health experts and affected farmworkers petitioned for its removal based on its known neurological danger, Allowing unlimited use of Roundup (glyphosate) long after it was shown to contribute to deadly non-Hodgkin’s lymphoma in heavy users and it devastated the treasured monarch butterfly, now driven to near extinction in North America, Approving hundreds of neonicotinoid systemic insecticides, now the most widespread insecticide in the country where they are decimating honey and native bees and other key pollinators and beneficial species; and Registering dicamba in a highly volatile herbicide, a shocking blunder later overruled by a federal court ruling that stated OPP “not only substantially understated the risks …. It also entirely failed to acknowledge other risks, including those it was statutorily required to consider.” Take action: Tell EPA and Congress that the […]

(Beyond Pesticides, October 28, 2021) A study published in Frontiers in Environmental Science finds the popular herbicide glyphosate negatively affects microbial communities, indirectly influencing plant, animal, and human health. Exposure to sublethal concentrations of glyphosate shifts microbial community composition, destroying beneficial microorganisms while preserving pathogenic organisms. Glyphosate is the most commonly used active ingredient worldwide, appearing in many herbicide formulas, including Bayer’s (formerly Monsanto) Roundup®. The use of this chemical has been increasing since the inception of crops genetically modified to tolerate glyphosate over two decades ago. The toxic herbicide readily contaminates the ecosystem with residues pervasive in both food and water commodities. In addition to this study, the scientific literature commonly associates glyphosate with human, biotic, and ecosystem harm, as a doubling of toxic effects on invertebrates, like pollinators, has been recorded since 2004. The authors caution, “[O]utbreaks of several animal and plant diseases have been related to glyphosate accumulation in the environment. Long-term glyphosate effects have been underreported, and new standards will be needed for residues in plant and animal products and the environment.” With an increasing number of reports on the relationship between glyphosate and human health, including potential effects on the human gut microbiome, advocates are calling on global leaders to eliminate chemical […]

(Beyond Pesticides, October 26, 2021) The Office of Pesticides Programs within the U.S. Environmental Protection Agency has become so captured by industry that it has lost sight of its health and environmental mission, according to a scathing critique issued today by 37 environmental, public health, and sustainable agriculture groups, including beekeeper councils. Led by Public Employees for Environmental Responsibility (PEER) and Beyond Pesticides, the groups are urging the Biden administration to adopt reforms within OPP to ensure pesticide approval and use decisions are science-based. EPA’s OPP has registered more than 18,000 separate pesticide products — far more than any other country — and more than 2 billion pounds of pesticides are sold annually in the U.S. They are used annually over roughly 250 million acres of farmland, across millions of acres of urban and suburban lands, and inside millions of homes, schools, and other buildings.  The coalition letter points to employee reports that managers within  OPP – Push through “Yes packages” of pesticide approvals greased by industry lobbying; Suppress toxicological and other concerns raised by professional staff; and Engage in outrageous waivers of vital toxicity study requirements, instead relying on “conditional” registrations to allow pesticide uses, despite missing key data. Seeing […]

(Beyond Pesticides, October 21, 2021) A study published in Environment International finds higher rates of various cancers among agricultural workers, with multiple myeloma (blood cancer) and melanoma (skin cancer) disproportionately impacting female farmers. Although research studies link cancer risk to genetic and external factors (e.g., cigarette smoke), there are increasing reports and scientific studies that pesticide exposure augments the risk of developing common cancers like melanoma and less common cancers like multiple myeloma. This study highlights the importance of understanding how pesticide use can increase the risk of latent diseases, which do not immediately develop upon initial exposure. The researchers note, “Given the large size of the agricultural population worldwide and the presence of various potential hazards in its working environment, such epidemiological data are important in improving occupational health measures and ensuring better workers’ health.” To investigate the cancer incidence patterns, researchers evaluated data from the AGRICOH database involving various international studies. The studies assessed pesticide exposure scenarios, which researchers use to determine the etiological (causal) agent of cancer incidences among farmers relative to the general population. Researchers analyzed data from eight different AGRICOH groups in various countries: France (AGRICAN), the U.S. (AHS, MESA), Norway (CNAP), Republic of Korea (KMCC), Denmark […]

(Beyond Pesticides, September 10, 2021) Research conducted in Thailand shows that exposures to pesticides, even at low levels, can impact the human endocrine system and distort thyroid function. The study looked specifically at interactions of genetics and environment: it investigated associations between variations in genes involved in pesticide metabolism and altered thyroid hormone concentrations in agricultural workers. This research underscores some of the complexity and difficulty of determining human vulnerability to impacts of pesticide exposures, given genetic variables. Beyond Pesticides believes that this very complexity is a cogent argument for anchoring regulation of pesticides in the Precautionary Principle. If exposure to a pesticide can cause damage to human (or environmental) health, it sometimes will do so. Thus, to protect people’s health, agriculture and other land management practices must transition from the use of synthetic pesticides to broad adoption of organic regenerative approaches that obviate the need for such chemicals. This research is part of a longitudinal study that seeks to evaluate sub-chronic impacts, on thyroid hormone levels, of repeated exposures to a variety of pesticides. The farmworkers studied in this phase comprise two groups: those working on organically managed farms (216 subjects), and those working on conventional farms that use pesticides […]