(Beyond Pesticides, June 22, 2022) Bad news is piling up for Bayer (Monsanto) and its carcinogenic flagship weed killer, glyphosate (Roundup). Last week, the Court of Appeals for the Ninth Circuit handed down a ruling that held the U.S. Environmental Protection Agency’s (EPA) 2020 approval of its notorious weed killer glyphosate unlawful. Then, yesterday, the U.S. Supreme Court declined to consider (deny certiorari) Bayer’s “Hail Mary” petition attempt to save the company from being held accountable to those diagnosed with cancer after using Roundup (glyphosate) herbicides. In both cases, the courts are acting as a check on a company, while EPA regulators charged with stopping this behavior continue to rubber stamp the agrichemical industry’s dangerous decisions. This is not the first time that the Supreme Court has upheld the rights of victims of the pesticide industry. In 2004, Bates v. Dow Agrosciences (U.S. Supreme Court, No. 03-388), the court found: “The long history of tort litigation against manufacturers of poisonous substances adds force to the basic presump­tion against pre-emption. If Congress had intended to deprive injured parties of a long available form of compen­sation, it surely would have expressed that intent more clearly. See Silkwood v. Kerr-McGee Corp., 464 U. […]

(Beyond Pesticides, June 16, 2022) Farmed salmon serves as an inferior food source, accumulating more toxic chemicals in fatty tissue with fewer healthy nutrient properties based on a study from the University of Bergen, Norway and Alternative Medicine Review. However, the issue of toxic chemical contamination in fish dates back decades with investigations demonstrating high levels of persistent organic pollutants (POPs), including polybrominated diphenyl ethers (PBDEs) flame retardants restricted or banned in the U.S. and U.K., polychlorinated biphenyl (PCBs), dioxin (a by-product of pesticide manufacturing), and ethoxyquin (a pesticide preservative in fish feed). The aquaculture industry (e.g., farmed seafood/fish) repeatedly faces sustainability issues, failing to adhere to environmental regulations and threatening marine health. Extensive use of pesticides in local marine ecosystems has induced coastal habitat loss and increased genetic and health risks to wild marine populations. Moreover, insecticides used to kill salmon parasites (e.g., fish lice) has led to widespread disease persistence and pest resistance. Marine species biodiversity is rapidly declining due to overfishing, global warming, pathogens, and pollution. Thus, further biodiversity loss can change aquatic and terrestrial ecosystem functions and reduce ecosystem services. Food analysis results find the consumption of farmed salmon fillets contributes to higher rates of metabolic disorders, including diabetes and obesity. These farmed salmon also contain levels […]

(Beyond Pesticides, June 14, 2022) The ringleader of a pesticide smuggling operation conducted across the United States border with Mexico has been sentenced to eight months in prison by a U.S. District Court Judge. According to a press release by the U.S. Attorney’s Office for the Southern District of California, Sofia Mancera Morales used individuals recruited over social media Bovitraz and Taktic, pesticide products banned in the US that pose hazards to pollinators and cancer risks to humans. “In exchange for ill-begotten profits, this cavalier smuggling operation was more than willing to risk the public’s health and the honeybee industry, which is critical to pollinating our food supply,” said U.S. Attorney Randy Grossman. While the Department of Justice deserves praise for this enforcement action, health and environmental advocates say that more must be done to stop illegal pesticide sales. A quick search for the two pesticide products in question brings up webpages, including well-known sites like Etsy.com, where the same illegal pesticides cited in this case are currently being sold to U.S. consumers. Over Facebook, Ms. Morales offered to pay individuals between $40-150 per package of pesticide products they delivered across the border. Those recruited were instructed to open a […]

(Beyond Pesticides, June 7, 2022) Bumblebee colonies exposed to low levels of the weed killer glyphosate are unable to adequately regulate nest temperature, imperiling the next generation of bumblebees and long-term colony growth and survival. This latest finding, published this month in the journal Science, is a stark reminder that a pesticide does not have to kill an animal outright in order to create effects that ultimately result in death and population declines. “Sublethal effects, i.e. effects on organisms that are not lethal but can be seen, for example, in the animals’ physiology or behaviour, can have a significant negative impact and should be taken into account when pesticides are approved in future,” said Anja Weidenmüller, PhD, of the University of Konstanz, Germany. With regulators at the U.S. Environmental Protection Agency (EPA) refusing to adequately account for sublethal impacts, and myopically focused on the acute effects of pesticide exposure, bumblebee populations in the United States are in free fall and require urgent protective action. To better understand how glyphosate exposure affects bumblebee colony growth and brood (young larval bee) development, researchers first split colonies in two. One side of the colony was fed sugar water containing 5mg/liter of glyphosate, while […]

(Beyond Pesticides, June 2, 2022) A California judge ordered state-run pesticide spraying to cease on public, agricultural, wild lands, and private properties. The judge states that government officials fail to consider and minimize the potential health and environmental risk associated with pesticide use. Moreover, officials failed to notify the public on the risks of pesticide spraying. The suit was brought by the Environmental Working Group (EWG), the City of Berkeley and ten other public health, conservation and food safety organizations, including Beyond Pesticides. Board member of the California Environmental Health Initiative Nan Wishner states, “The court made the right decision to throw out CDFA’s plan to cement into place for the indefinite future the agency’s ‘spray now, ask questions later approach to pest management, which would have perpetuated the existing situation, in which Californians learn their yards or neighborhoods are to be sprayed only when the treatments are about to happen and have little or no recourse to stop the use of pesticides.”  On May 19, 2022, the Superior Court of California – County of Sacramento ruled to remove an environmental impact report allowing California’s Department of Food and Agriculture (CDFA) to spray pesticides at any time and any place. Removal […]

(Beyond Pesticides, May 31, 2022) Fifty years after the banning of DDT, the notorious insecticide is still harming iconic birds of prey along the California coastline. According to research published in Environmental Science and Technology, California condors and marine mammals along California’s coast are contaminated with several dozen different halogenated organic compounds (hazardous, often-chlorinated chemicals) related to DDT, chlordane, and other now-banned legacy chemicals. The findings highlight the incredible importance of addressing these original “forever chemicals,” and making certain that we do not continue to repeat the mistakes of the past with new and different, yet equally dangerous, chemistries. Between 1947 and 1971, the Montrose Chemical Corporation of California, the largest historical producer of DDT, released over 1,700 tons of DDT into the LA sewer system, which eventually made its way into the Pacific Ocean. During this time, several other companies discharged PCBs, leading to further chemical contamination of land and sediment. As recent as April 2021, scientists discovered 25,000 barrels likely containing DDT near Catalina Island along the southern California coast. These releases have resulted in serious environmental and health problems throughout the coastal food chain. Yet, as the present study shows, scientists are only beginning to understand the […]

(Beyond Pesticides, May 27, 2022) In a U.S. Environmental Protection Agency (EPA) court document filed on May 16, the agency signaled potential changes to the labeling it requires for “over the top” (OTT, or post-emergent) herbicides containing dicamba, a very problematic pesticide. The filing — in U.S. District Court for the District of Arizona, where EPA currently faces litigation about its 2020 dicamba registrations — comes as a result of Bayer, Inc.’s March 2022 proposed amendments to EPA registration for its XtendiMax herbicide, which contains dicamba and glyphosate. Beyond Pesticides has covered the dicamba saga for years, including the EPA Office of the Inspector General’s critical 2021 report citing an abandonment of science and assault on agency integrity for EPA’s dicamba decisions during the Trump years. Dicamba has been linked to cancer, reproductive effects, neurotoxicity, birth defects, and kidney and liver damage. It is toxic to birds, fish, and other aquatic organisms, and is known to leach into waterways after application. Dicamba also causes serious damage to non-GE (genetically engineered), non-target plants, damaging habitat and food sources for various organisms, especially for birds and insects. According to Progressive Farmer, EPA is currently considering some dicamba use restrictions after Bayer submitted them to […]

(Beyond Pesticides, May 26, 2022) A study published in The International Journal of Biochemistry & Cell Biology finds environmental exposure to neurotoxic pesticides increases Parkinson’s Disease (PD) risk through gastrointestinal (GI) disruption. Research finds exposure to chemical toxicants, like pesticides, can cause neurotoxic effects or exacerbate preexisting chemical damage to the nervous system. Although the mechanism by which pesticides induce disease development remains unclear, this study suggests environmental pesticide exposure disrupts GI cells responsible for supporting the autonomic nervous system. Enteric glial cells (EGCs) are GI cells that play a critical role in the functional changes that accompany GI dysfunction, as this dysfunction is one of the earliest symptoms indicating the onset of PD. Parkinson’s disease is the second most common neurodegenerative disease, with at least one million Americans living with PD and about 50,000 new diagnoses each year. The disease affects 50% more men than women, and individuals with PD have a variety of symptoms, including loss of muscle control and trembling, anxiety and depression, constipation and urinary difficulties, dementia, and sleep disturbances. Identifying early biomarkers of PD, such as pesticide-mediated toxicity on GI cells, is crucially important as symptoms intensify overtime, with no current cure for this fatal disease. While only […]

(Beyond Pesticides, May 24, 2022) New research is providing strong causal evidence that Gulf War Illness (GWI) is the result of exposure to sarin gas, an organophosphate nerve agent used by Saddam Hussein as a chemical weapon during the Gulf War. The findings, published earlier this month in Environmental Health Perspectives, have important implications for the hundreds of thousands of American service members suffering from a constellation of chronic symptoms without a true understanding of how they became sick. “Quite simply, our findings prove that Gulf War illness was caused by sarin, which was released when we bombed Iraqi chemical weapons storage and production facilities,” said Robert Haley, MD, lead author of the study and epidemiologist at University of Texas Southwestern. “There are still more than 100,000 Gulf War veterans who are not getting help for this illness and our hope is that these findings will accelerate the search for better treatment.” Sarin was first synthesized in the late 1930s by Nazi chemists working for IG Farben (a consortium that included Bayer) in an attempt to create stronger and more powerful insecticides. Sarin is a G-series organophosphate (named after the scientists that created them), characterized by high acute toxicity and […]

(Beyond Pesticides, May 23, 2022)  The climate change-induced increase in wildfire frequency and intensity has lent new urgency to efforts to manage so-called “invasive” plants. Unfortunately, the herbicide-based approach favored by many is both counterproductive and hazardous. It must be replaced by an organic system, incorporating biological control agents like goats and establishing a more resilient ecology.    Tell your county/city officials to replace herbicides with organic vegetation management. Tell EPA and Congress that herbicides must be evaluated in the context of the availability of organic systems. Use of the herbicide indaziflam is an example of the ineffectiveness of management based on herbicides. While indaziflam is considered a “selective” herbicide, it actually kills and prevents germination of a wide range of broad-leaved plants and grasses and comes close to being a soil sterilant. The action on seedlings is long-lasting, thus inhibiting the growth and establishment of a resilient plant community that is resistant to invasion. Given its persistence and nonselective action and the extent of the damage it causes to native soil seed banks and plant biodiversity, indaziflam could contribute to the eventual ecological collapse of ecosystems where it’s applied, similar to the cascading impacts of the systemic insecticides, fipronil and […]

(Beyond Pesticides, May 19, 2022) A study published in the Journal of the American Heart Association finds a correlation between the number of fires fought annually and atrial fibrillation (AF), one of the most common medical arrhythmias that increases the risk of stroke, heart failure, and other cardiovascular health issues. In the firefighting occupation, firefighters can experience exposure to chemicals and particulate matter in smoke, pollutants, volatile organic compounds, and polycyclic aromatic hydrocarbons (PAHs) that increase cardiovascular (heart) and respiratory distress risk through oxidative stress and autonomic function disruption. However, firefighters encounter both personal and occupational (work-related) risk factors for cardiovascular diseases, making this subset of the population particularly vulnerable to heart-related fatalities. Considering firefighters live 10 to 15 years less than non-firefighters, studies like these are significant for understanding how chemical exposure contributes to health and wellness disparities. Lead author Paari Dominic, Ph.D., notes, “Clinicians who care for firefighters need to be aware of the increased cardiovascular risk, especially the increased risk of [AF], among this unique group of individuals… The conditions that elevate their risk further, such as high blood pressure, type 2 diabetes, lung disease and sleep apnea, should be treated aggressively. In addition, any symptoms of [AF], such as […]

(Beyond Pesticides, May 12, 2022) A report published in Environmental Health finds that exposure to environmentally relevant concentrations of pesticides can alter gut microbial communities, as demonstrated through fecal samples. Over 300 environmental contaminants and their byproducts, including pesticides, are chemicals commonly present in human blood and urine samples. Ample evidence demonstrates that environmental contaminants, including pesticides, negatively affect the human mouth and gut microbes. However, fecal samples provide an accurate representation of the microbial community existing in the gut. These toxicants can alter hormone metabolism, which adversely affects health outcomes. Adverse health effects of environmental contaminants include reproductive and developmental defects, diabetes, cardiovascular disease, liver disease, obesity, thyroid disorders, and improper immune operation. Although studies show how chemical exposures affect human health, more research is now questioning how these toxic chemicals influence gut health. Therefore, studies like these highlight the importance of evaluating how chemical contaminants deregulate normal bodily function through microbiome changes. The report notes, “Our results highlight the need for future dietary intervention studies to understand effects of pesticide exposure on the gut microbiome and possible health consequences.” Researchers examined dietary exposure to 186 common pesticide residues in the fecal excrement to determine impacts on the microbiome among 65 twins in the United Kingdom. […]

(Beyond Pesticides, May 10, 2022) Widespread weed resistance on chemical corn and soybean farms is leading farmers to till their fields more often, significantly increasing greenhouse gas (GHG) emissions. These findings were published late last month in the journal Nature Food by a team of Iowa State University researchers. With agricultural practices accounting for roughly 10% of U.S. GHG emissions, and 25% of worldwide releases, farming practices that preserve soil health and sequester GHGs are essential for the future of food production. Tillage is a farming practice that can provide a range of benefits for crop production, but only in the right conditions. A range of tillage practices exist, ranging from yearly conventional tillage, where most crop residue is plowed into the soil, to conservation tillage where some residue remains, and no-till systems where the soil remains covered. Repeated tillage causes significant harm to soil structure and biology, and result in erosion and the release of GHGs like carbon dioxide, methane, and nitrous oxide from soil into the atmosphere. The harms of tillage have led both chemical and organic farmers toward no-till or reduced tillage systems. Organic no-till farming, as practiced by farming groups like the Rodale Institute, employs the […]

(Beyond Pesticides, May 9, 2022) While the U.S. Environmental Protection Agency (EPA) updated its guidelines for pollinator risk assessments in 2014, the agency continues to either fail to conduct full assessments, or dismiss concerning data it receives. EPA appears to discount threats like the insect apocalypse, evidenced by a 75% decline in insect abundance, which threatens not only global ecosystems, but also food production that depends on animal pollination. As pesticides move through the food web, birds are also at risk. Bird numbers are down 29% since Rachel Carson wrote Silent Spring in 1962. Tell EPA To Protect Against Other Threats to Pollinators. Tell Congress To Insist that EPA Does Its Job. The problem is highlighted by EPA’s recent Interim Decision on fenbuconazole, in which the agency notes that, “For larval bees, RQs (risk quotients) exceed the LOC (level of concern) for all pollinator attractive uses including when assessed at the lowest application rate of 0.0938 lb a.i./Acre (RQ = 1.1).” Yet in the same document, the agency declares that “…the benefits of fenbuconazole (e.g., efficacy in management of fungal pathogens) outweigh any remaining risk and that continuing to register fenbuconazole provides significant benefits, including its ability to increase crop […]

(Beyond Pesticides, May 6, 2022) A December 2021 report commissioned by the trade group Salmon Scotland concludes that the use of pesticide products by the nation’s salmon farms represents potential risk to “wild” swimmers (those who swim in open ocean waters). The report’s primary finding is that the use of insecticide products containing azamethiphos (an organophosphate), deltamethrin, and hydrogen peroxide to control sea lice in farmed fish contaminates sea water and, thus, threatens swimmers in the areas around the farms. Beyond Pesticides has reported on pesticide use in aquaculture, and most recently, on developing resistance — in the parasitic lice (Lepeophtheirus salmonis) that endanger both wild and farmed fish populations in the North Atlantic — to some of the chemical treatments used by aquaculturists to combat the parasite. The intense exploitation of wild fish and other marine creatures for human food (and as an ingredient in animal feeds) has caused, in recent decades, depletion of fish and seafood stocks across the world. The aquaculture industry — in which various aquatic species (fish, shellfish, and some plants) are bred, raised, and harvested in the open ocean — has grown rapidly as a response. Since the 1960s, the farming of salmon in the […]

(Beyond Pesticides, May 3, 2022) Exposure to a commonly used fungicide considered to be ‘slightly toxic or nontoxic’ to pollinators makes male mason bees less likely to find a mate, jeopardizing future generations of critically important pollinators. This determination comes from research recently published in the Journal of Applied Ecology by scientists at Germany’s University of Würzburg. The timing of these findings comes after the U.S. Environmental Protection Agency (EPA) reapproved uses of fenbuconazole, the fungicide in question, late last year without completing all required studies on pollinator health effects. Horned mason bees (Osmia cornuta), a solitary bee species, have a complex mating process that includes a range of “pre-copulatory behaviors” used by male bees attract females. Males create thoracic vibrations with their flight muscles, rub the eyes of female bees with their antennae, and emit a distinct odor from their body. If the female likes the presentation, she will mate with the male. Otherwise, she will move him to the side and wait for another male to try to win her affection. To see how this process was influenced by pesticide exposure, researchers conducted a range of different experiments. For the first, newly emerged male and female bees were […]

(Beyond Pesticides, April 28, 2022) A study in Environmental Research finds that glyphosate’s primary metabolite (breakdown product), aminomethylphosphonic acid (AMPA), induces DNA damage through oxidative stress among subpopulations of primary school children. Although pyrethroid and chlorpyrifos metabolites can induce oxidative stress, this study is the first to investigate AMPA’s association with adverse health effects, rather than solely the effects of the active ingredient, glyphosate, in Roundup and other formulations. Glyphosate is the most commonly used active ingredient worldwide, appearing in many herbicide formulations, readily contaminating soil, water, food, and other resources. Chemical use has been increasing since the inception of crops genetically modified to tolerate glyphosate. However, studies demonstrate glyphosate is among the most prevalent pesticide contributors to human, biotic, and ecosystem harm. According to research, herbicide toxicity to invertebrates has doubled since 2004. Although research links glyphosate exposure to cancer, specifically non-Hodgkin lymphoma, much less research considers the effects that metabolites have on children who are more vulnerable to chemical exposure. Ecological and health risk assessments primarily focus on active ingredients in pesticide products, overlooking the potential impacts of metabolites. Thus, studies like these highlight the need to assess the implications of metabolite exposure to protect human, animal, and environmental health. The study notes, “Our […]

(Beyond Pesticides, April 21, 2022) A literature review published in Royal Society finds that ‘inert’ ingredients’ in pesticide formulations adversely affect the health of bees and other wild pollinators. Inert ingredients, also known as “other” ingredients, and not disclosed by name on pesticide product labels, facilitate the action of active ingredients targeting a specific pest. Although both ingredients have chemical and biological activity, most studies on agricultural chemical toxicity focus on the active ingredient, assuming that inert ingredients are “nontoxic.” The U.S. Environmental Protection Agency (EPA), in regulating pesticides, assesses the toxicity of individual active ingredients on bees through various testing methods. However, there are no requirements for EPA to test inert ingredients to the same degree, despite evidence demonstrating these chemicals harm pollinators. Moreover, EPA does not require pesticide manufacturers to disclose the inert ingredients used in any product as the information is confidential. Both wild and commercial bees and other pollinators encounter multiple stressors, including pesticides, parasites, and poor nutrition, that act together to increase the risk of bee mortality. Therefore, reviews like these highlight the need for pesticide testing to consider the effects of all product ingredients, regardless of perceived toxicity. The researchers caution, “We argue that ‘inert’ ingredients […]

(Beyond Pesticides, April 20, 2022) A University of Michigan study is the first to highlight that maternal pesticide exposure during pregnancy adversely affects sleeping patterns for offspring later in life, specifically for females. Prenatal development is one of the most vulnerable periods of exposure as the fetus is most susceptible to the harmful effects of chemical contaminants. Many studies indicate that prenatal and early-life exposure to environmental toxicants increases susceptibility to diseases, from learning and developmental disabilities to cancer. However, the toxicity of pesticide exposure ad its full impact on the nonagricultural population in the U.S., especially women. Given research links to sleep-related disorders and neurological and cognitive development, studies like this can help government and health officials identify how pesticides’ impact on the brain elevates health concerns. The authors note, “Overall, these results are of public health importance considering the continued widespread agricultural and possibly residential use of pyrethroids and chlorpyrifos [in Mexico]…Thus, our results underline the importance of additional research studies that include both larger samples and assessment of unregulated pesticides, as well as studies that consider the underlying mechanisms explaining sex differences.” Levels of inadequate sleep patterns are rising among children and adolescents. Reports find variability in sleep duration results in higher rates of depression, anxiety, and […]

(Beyond Pesticides, April 19, 2022) Both houses of Maine’s legislature have just approved a bill that would, by 2030, ban pesticides that contain PFAS chemicals — the so-called “forever chemicals.” The bill’s next stop is the Appropriations Committee, for approval of $200,000 in annual funding to enact the bill; if successful there, it will move to the desk of Maine Governor Janet Mills for her signature. The legislation is one of a suite of lawmaker efforts in the state to address the growing PFAS problem with which localities across the U.S. are struggling. In this Daily News Blog article, Beyond Pesticides continues its coverage of the scourge of PFAS chemicals, particularly as it relates to pesticide use and the use of fertilizers made from PFAS-contaminated “biosludge” from municipal treatment facilities. PFAS — “per- and poly-fluoroalkyl substances” — are any of a family of more than 9,000 synthetic chemicals, invented in, and widely deployed since, the 1950s in a multitude of industrial and consumer products. PFAS molecules are made up of a chain of linked carbon and fluorine atoms; the carbon–fluorine bond is one of the strongest chemical bonds that exists, which means that these compounds do not break down in the […]

The organic solutions to problems highlighted in the latest issue of Pesticides and You—based on the importance of healthy ecosystems and public health protection—are within reach, and the data creates an imperative for action now that phases out pesticides within a decade, while ensuring food productivity, resilient land management, and safe food, air, and water. (Beyond Pesticides, April 15, 2022) The current issue of Pesticides and You, RETROSPECTIVE 2021: A Call to Urgent Action, is a look at a year of science, policy, and advocacy that informs both the existential problems that the U.S. and the world are facing due to toxic pesticide dependency, and solutions that can be adopted now. The information in this issue captures the body of science that empowers action at the local, state, and federal level, and provides a framework for challenging toxic pesticide use and putting alternatives in place. The issue finds that 2021 was a pivotal year in both defining the problem and advancing the solution. This year in review is divided into nine sections that provide an accounting of scientific findings documenting serious pesticide-induced health and environmental effects, disproportionate risk to people of color and those with preexisting conditions, regulatory failures, at the same time […]

(Beyond Pesticides, April 12, 2022) A recent study published in Scientific Reports warns that parasitic salmon lice (Lepeophtheirus salmonis) in Pacific Ocean open-net fish farming operations are becoming resistant to emamectin benzoate (EMB), an active ingredient used to control salmon lice population in North America, both in the U.S. and British Columbia, Canada. Previously, researchers believed parasitic salmon lice only had high rates of chemical resistance in the Atlantic region due to the mixing of farmed and wild salmon. However, Pacific salmon lice are exhibiting similar rates of decreased sensitivity to EMB from various sources, including a decrease in the wild Pacific salmon population, overuse of chemical treatments, and reliance on single chemical treatments. The aquaculture industry (e.g., farmed seafood/fish) repeatedly faces sustainability issues, failing to adhere to environmental regulations and threatening marine health. Extensive use of pesticides to rid the parasite has led to widespread resistance to multiple pesticides, prompting increasing infection rates among North Atlantic salmon populations. These parasites endanger both farmed salmon and wild salmon, in addition to other local species of fish. In this context, pesticide treatments contributes to resistance among lethal pest populations, especially in ecologically vulnerable and interconnected ecosystems like ocean basins. The researchers caution, “Salmon […]

(Beyond Pesticides, April 5, 2022) A meta-analysis by the Federal University of Technology – Paraná finds the herbicide 2,4-D causes indiscriminate harm, increasing the mortality rate among exposed animals. The severity of chemical exposure relies on species sensitivity, exposure rate, and lifecycle stage. However, commercial formulations of 2,4-D, commonly used in the environment, prompt a higher species mortality rate than technical (pure) 2,4-D alone. Like many other common herbicides such as glyphosate, 2,4-D has global uses that allow the chemical to accumulate in the environment, including soils, waterways, and tissues of non-target species. Therefore, meta-analyses like this help local and government officials make holistic decisions regarding environmental contaminants that incorporate conclusions from various studies. Using the Web of Science and Scopus databases, researchers compiled various studies (or meta-analyses) on the lethality of 2,4-D in different animal species (e.g., vertebrates, invertebrates). Researchers evaluated each study regarding the mortality rate of control and experimental groups, animal sensitivity to chemical exposure during a specific life stage, chemical formulation (e.g., commercial or technical), and exposure routes causing mortality. The analysis demonstrates that vertebrates experience higher mortality rates from 2,4-D exposure, with fish and birds presenting the highest mortality rate. Regarding life stages, larval and adult […]