(Beyond Pesticides, November 1, 2013) Insecticides commonly used in homes and schools are associated with behavioral problems in children, according to a recent study by Canadian researchers. The study investigates exposure to pyrethroid pesticides, used in more than 3,500 products, including flea and tick controls, cockroach sprays, and head lice controls. The study, Urinary metabolites of organophosphates and pyrethroid pesticides and behavioral problems in Canadian children, published in the journal Environmental Health Perspectives, raises serious concerns about the impact of pyrethroids, which are increasingly used as a replacement for organophosphates. This study uses data from the Canadian Health Measures Survey (2007-2009), a nationally representative survey, so researchers are able to apply these findings to the entire population of Canadian children. In a previous study among U.S. children, researchers at the National Health and Nutrition Examination Survey (NHANES) examined the metabolites of pyrethroids in children below the age of six. Similarly, they found pyrethroid insecticides in more than 70 percent of the samples, concluding that children had significantly higher metabolite concentrations than those of adolescents. Together these studies demonstrate that exposure is widespread, with real impacts to human health. In the recent study, researchers analyzed organophosphate and pyrethroid metabolites in the […]

(Beyond Pesticides, October 29, 2013) Early-life exposure to the herbicide atrazine makes frogs more susceptible to death from chytrid (Batrachochytrium dendrobatidis), a fungal disease implicated in amphibian declines across the globe. The research, Early-life exposure to a herbicide has enduring effects on pathogen-induced mortality, published in the Proceedings of the Royal Society B and led by University of South Florida (USF) biologist Jason Rohr, Ph.D, provides critical information for scientists hoping to stem the global demise of amphibian populations. “Understanding how stressors cause enduring health effects is important because these stressors might then be avoided or mitigated during formative developmental stages to prevent lasting increases in disease susceptibility,” Dr. Rohr explains. Researchers exposed tadpoles to atrazine at levels found in the environment for a period of  six days during the animal’s development, in combination with exposure to chytrid fungus (linked to worldwide amphibian decline), resulted in increased mortality 46 days later. According to the study, “[E]arly-life exposure to atrazine altered growth and development, which resulted in exposure to chytrid at more susceptible developmental stages and sizes, and reduced tolerance of infection, elevating mortality risk at an equivalent fungal burden to frogs unexposed to atrazine. Moreover, there was no evidence of […]

(Beyond Pesticides, October 28, 2013) Scientists at Washington State University (WSU), in a laboratory study,  determined that exposure to the insecticide DDT ””banned in the U.S. since 1972, but still used today in developing countries for malaria abatement programs””impacts multiple generations, ultimately contributing to obesity three generations down the line. The study, published in the journal BMC Medicine, provides the scientific community with new information on multi-generational impacts of pesticide exposure. Lead researcher Michael Skinner, PhD., professor of biological sciences at WSU, and colleagues exposed pregnant rats to DDT to determine the long-term impacts to health across generations. The study, Ancestral dichlorodiphenyltrichloroethane (DDT) exposure promotes epigenetic transgenerational inheritance of obesity, finds that the first generation of rats’ offspring developed severe health problems, ranging from kidney disease, prostate disease, and ovary disease, to tumor development. Interestingly, by the third generation more than half of the rats have increased levels of weight gain and fat storage. In other words, the great grandchildren of the exposed rats are much more likely to be obese. “Therefore, your ancestors’ environmental exposures may influence your disease development even though you have never had a direct exposure,” the study finds. Previous studies have demonstrated that exposure to […]

(Beyond Pesticides, October 3, 2013) According to new research, residents are more highly exposed to organophosphate and pyrethroid pesticides in New York City (NYC) than in the U.S. overall.  Researchers from the city’s Department of Health and Mental Hygiene reviewed the 2004 NYC Health and Nutrition Examination Survey (NYC HANES) to compare its pesticide exposure patterns in an urban environment with the nation as a whole. The NYC HANES includes a biomonitoring component to evaluate pesticide exposures by measuring concentrations of organophosphate and pyrethroid metabolites in urine. According to the authors, the findings underscore the importance of considering pest and pesticide burdens on cities, where a dense population results in a single exposure source affecting many people at the same time when regulating pesticide use. Organophosphate metabolites were measured in the urine of 882 New Yorkers, while 1,452 residents were tested for pyrethroid metabolites. As the researchers explain, the building density and disrepair in parts of NYC likely increased the chances of a pest infestation, which in turn can lead to the reliance on indoor pesticide use. By the 1980’s, organophosphates were the most common class of insecticides in the U.S., and were used indoors until the early 2000’s when […]

(Beyond Pesticides, September 20, 2013) A study of women in Northern California farm towns finds that those living within three miles of strawberries fields treated with methyl bromide gave birth to smaller, lighter babies. Methyl bromides, a fumigant pesticide injected into soils to eliminate soil-borne pests, can volatize into the air exposing nearby neighborhoods. The U.S. and other developed countries have banned the use of methyl bromide under an international treaty that recognized the role of chemicals like methyl bromide to deplete the ozone layer. However, some farmers continue to use the fumigant on strawberries and other crops due to the “critical use exemption” (CUE) stipulation of the laws, which allows the chemical to continue to be used when there are no feasible alternatives. The study, published in Environmental Health Perspectives, examined the health of babies born to 442 pregnant women living in Salinas Valley, CA in 1999 and 2000, when methyl bromide was widely used.   Utilizing data from California’s Pesticide Use Reporting System, the study was able to identify residences that were within 5 kilometers of methyl bromide application. Researchers find that women exposed to the chemical during their second trimester have babies that are  four ounces lighter […]

(Beyond Pesticides, September 11, 2013) In a report released Monday, the Government Accountability Office (GAO) finds that the U.S. Environmental Protection Agency (EPA)’s use and oversight of conditional registrations is lacking and unreliable. Conditional registration allows pesticides onto the consumer market without all the required data to assess the chemical’s safety. This has created many serious human and environmental health problems, including bee decline, tree death and potential increases in human health risks. GAO recommends that EPA better track conditional registrations, however, Beyond Pesticides and other concerned groups urge the agency to cancel registrations until all relevant data is submitted and reviewed. According to the findings of the GAO’s report, EPA’s system for tracking pesticides with conditional registration is unreliable and thus, the total number of conditional registrations granted is unclear.   This lack of a reliable system for managing conditional registrations constitutes an ”˜internal control weakness’ because the agency lacks an effective mechanism for program oversight and decision making, according to federal internal control standards cited by GAO. The report states, “The extent to which EPA ensures that companies submit additional required data and EPA reviews these data is unknown. Specifically, EPA does not have a reliable system, such […]

(Beyond Pesticides, August 30, 2013) Months after Central American health ministries issued a  joint declaration citing kidney disease as a top public health priority, the World Bank just approved a new loan to expand sugar cane plantations in Nicaragua. The Bank’s loan represents renewed support for an industry whose workers have been devastated by the disease, which has increasingly been linked to pesticide exposure and exacerbated by heat stress. Kidney disease afflicts agricultural workers in sugar cane fields, killing thousands each year in Central America as well as in Sri Lanka and India. Scientists have yet to definitively uncover the cause of chronic kidney disease (CKD), although emerging research points to toxic heavy metals contained in pesticides as one of the primary culprits. CKD is a condition characterized by a gradual loss of kidney function and is often lethal for poor agricultural workers. As the kidneys begin to fail, wastes can build in the blood causing complications such as high blood pressure, anemia, weak bones, poor nutritional health and nerve damage. Several published studies demonstrate that exposure to certain  organochlorine pesticide products and their heavy metal contaminants used on sugar cane plantations are causally linked to CKD. The recent joint […]

(Beyond Pesticides, August, 2, 2013) A new study published in the American Journal of Epidemiology concludes that farmers using herbicides are nearly two and a half times as likely to be treated for depression as those who did not use herbicides. Furthermore, farmers who are exposed for greater periods of time are also afflicted with greater risk of developing depression, raising concerns of the harm chemicals can cause to mental health. Building on substantial research supporting the link between pesticide exposure and neurological damage, this study examines the role that pesticides play in the overall health of farmers, and gives further weight to the importance of choosing organic food. Researchers surveyed 567 farmers from France, questioning them on the frequency of their use of fungicides, insecticides, and herbicides, to determine how pesticide exposures were linked to the risk of developing clinical depression. Lead researchers and associate professor at the Harvard School of Public Health, Marc Weisskopf, PhD, said while the results are unclear, they “suggest we should not be ignoring herbicides just because they’re targeting plants.” Previous research has already suggested that pesticides, particularly organophosphates, cause a variety of serious neurological health problems, including Parkinson’s disease. This is not surprising, […]

(Beyond Pesticides, July 12, 2013) New research concludes that exposure to a combination of both arsenic and estrogen, at levels U.S. Environmental Protection Agency (EPA) considers “safe” for humans, can cause cancer at elevated levels in prostate cells. Texas Tech University researchers revealed that humans exposed to a combination of both toxicants were almost twice as likely to develop cancerous cells in their prostate. The study is published in the peer-reviewed journal The Prostate. While it is established that both arsenic and estrogen can cause cancer, the research raises concerns about the dangers of chemicals in combination, and the efficacy of regulations that are established by testing one chemical at a time. Kamaleshwar Singh, PhD., is an assistant professor at the Institute of Environmental and Human Health at Texas Tech. “The majority of cancers are caused by environmental influences,” Dr. Singh remarked to Texas Tech Today, “Only about 5 to 10 percent of cancers are due to genetic predisposition. Science has looked at these chemicals, such as arsenic, and tested them in a lab to find the amounts that may cause cancer. But that’s just a single chemical in a single test. In the real world, we are getting exposed […]

(Beyond Pesticides, June 28, 2013) The U.S. Environmental Protection Agency (EPA) released a draft “State of the Science” report last week acknowledging that low dose responses “do occur in biological systems” while defending its current risk assessment procedures as adequate for evaluating low dose effects. This report comes after EPA’s long running failure to fully implement a 1996 Congressionally mandated program to evaluate endocrine disruptors, and heavy criticism last year from prominent scientists who said EPA’s testing procedures are outdated. In 1999 the Natural Resources Defense Council (NRDC) filed a lawsuit against the EPA for failing to meet a statutory deadline for implementation of the Endocrine Disruptor Screening Program (EDSP) required under the 1996 Food Quality Protection Act, forcing the EPA to make a settlement agreement. As a result of  NRDC et al. v. EPA (No. C-99-03701 CAL) filed in the Northern District of California, EPA agreed to start requiring screening and testing of certain chemicals varying by date, using a tiered system. EPA’s two-tiered screening and testing system, requires that EPA will identify which chemicals are able to interact with the endocrine system in Tier 1. Tier 2 screening process was designed to go one step further, requiring EPA […]

(Beyond Pesticides, June 19, 2013) The Director of the National Institute of Environmental Health Sciences (NIEHS), Linda Birnbaum, PhD, is being criticized by some Republicans for authoring an article that describes linkages between endocrine disrupting chemicals and the onset of disease, as well as the need to understand and monitor the effects of these chemicals. Instead of encouraging efforts for greater understanding of these chemicals, the members of Congress instead blasted the article as a potential breach of National Institutes of Health (NIH) policy. NIEHS, a program of NIH, seeks to reduce the burden of human illness and disability by understanding how the environment influences the development and progression of human disease. The short article entitled, “When environmental chemicals act like uncontrolled medicine,” published online on May 7, 2013, in Trends in Endocrinology and Metabolism, lays out the case that environmental chemicals can produce unwanted endocrine effects, leading to an increase in certain diseases.  It states, “In the same way as physicians endeavor to understand and monitor the effect of medicines on endocrine pathways, we ought to achieve the same understanding and control of the effects on environmental chemicals.” Dr. Birnbaum also notes, “The proliferation of inadequately tested chemicals in […]

(Beyond Pesticides, May 30, 2013) New research published in the journal Neurology further supports the causative link between pesticide exposure and Parkinson’s disease. Emanuel Cereda, M.D., Ph.D., of the IRCCS university Hospital San Matteo Foundation in Pavia, Italy, and coauthor Gianni Pezzoli, M.D., analyzed 104 studies published between 1975 and 2011 to determine the link between pesticides and solvents to Parkinson’s disease. The researchers analyzed exposure using information on proximity to large farms likely to use pesticides, likelihood of well water consumption, and occupations that cause greater exposure to pesticides and solvents used to kill weeds, insects, fungus, and rodents. Overall, researchers found exposure to pesticides increased the risk of developing the disease by 33%  to 80%.   Some pesticides were considered to be of higher risk than others, with weed killers like paraquat and fungicides maneb and mancozeb causing twice the risk for development of Parkinson’s disease. While risk increased the longer people were exposed to pesticides, researchers indicate there is still a need for further research on the chemical threshold for harm to the brain. The study builds on recent research that has linked Parkinson’s disease to pesticide exposure. In a 2011 article published in the journal Molecular […]

(Beyond Pesticides, May 9, 2013) A review of the scientific literature of the toxic effects of glyphosate, one of the most popular weed killers in the U.S. and the active ingredient in Roundup, links the herbicide  to a wide range of diseases and suggests  that more research is needed. The review, conducted by a scientist at Massachusetts Institute of Technology (MIT), looks at the mechanisms through which the adverse effects may be happening and points to  the chemical’s inhibition of cytochrome P450 (CYP) enzymes, which plays the crucial role of detoxifying xenobiotics. Thus, glyphosate can enhance the negative effects of other environmental toxicants on the body. Authors argue that this has been a critically overlooked component in research on glyphosates’ toxicity to mammals. We “have hit upon something very important that needs to be taken seriously and further investigated,” Stephanie Seneff, PhD, lead author and research scientist at MIT, told Reuters. Not surprisingly, Monsanto, the developer of Roundup, the leading product containing glyphosate, has attempted to discredit the study, claiming that its product has a long track record of being safe – read Another Bogus “Study.” However, Beyond Pesticides has assembled  extensive documentation on the human health and environmental risks […]

(Beyond Pesticides, April 29, 2013) Dow AgroSciences, one of the nation’s largest pesticide makers, along with various food companies, have persuaded several members of Congress to endorse a bill that directs the Environmental Protection Agency (EPA) to reverse a proposed phase out of sulfuryl fluoride, a highly toxic food fumigant and potent greenhouse gas. If passed, the bill would make the U.S. one of only two western nations to allow sulfuryl fluoride on food, increase the number of American children ingesting unsafe levels of fluoride, and create a food poisoning risk for consumers who  purchase food that contains permissible levels of the fumigant. The  Pest Free Food Supply Act, H.R. 1496, sponsored by Rep. Tom Graves (R-GA) and 14 others, seeks to prevent the proposed  phase out  of sulfuryl fluoride from taking effect. The phase out, which EPA proposed in January 2011, was prompted by a  joint petition from the Fluoride Action Network (FAN), Environmental Working Group (EWG) and Beyond Pesticides. In seeking to prevent the phase out from taking effect, the bill’s sponsors have adopted Dow’s widely discredited talking points on the safety and necessity of sulfuryl fluoride fumigation. The public should know: ”¢ Of the few western nations […]

(Beyond Pesticides, April 26, 2013) Female agricultural workers experience the same hardships as their male counterparts, but have additional responsibilities and danger at home and in the field, according to a report released by the Association of Farmworker Opportunity Programs (AFOP). While women make up only 22 percent of agricultural labor in the U.S., AFOP makes a strong argument that women face disproportionate burdens, while at the same time earning less for their labor: On average they earn  just over $11,000 per year compared to male agricultural workers who earn $16,000. Through hundreds of interviews and focus groups of female farmworkers in California and Florida, AFOP revealed some of the most dangerous  conditions associated with farm work, among the worst being pesticide exposure. Carmela, a farmworker from Florida, indicated in the AFOP report that, “More than anything else, we have problems with pesticides. Sometimes they put us to work right after they’ve sprayed the pesticides. And this is bad for us because when we go in the field and start working with the plants, it gets in our eyes. It makes your head hurt too.” According to the EPA’s “Pesticide Industry Sales and Usage: 2000 and 2001 Market Estimates,” female […]

(Beyond Pesticides, April 24, 2013) Using the aquatic species Daphnia, commonly referred to as “water fleas,” scientists at North Carolina State University (NC State) determined that exposure to the pesticide pyriproxyfen impacted multiple generations, ultimately resulting in more male offspring, and causing reproductive problems in female offspring. Lead author Gerald LeBlanc, PhD, notes, “This work supports the hypothesis that exposure to some environmental chemicals during sensitive periods of development can cause significant health problems for those organisms later in life —and affect their offspring and, possibly, their offspring’s offspring.” The study, published in the journal PLoS One, provides the scientific community with new information on how organisms respond to the environmental signals resulting from pesticide exposure. Environmental cues normally determine whether the Daphina offspring will be male or female, according to the researchers. This study is part of an investigation to understand the mechanisms involved with these environmental cues. The NC State team had previously identified the hormone methyl farnesoate (Mf) as an important factor in determining the sex of the organisms at the embryotic stage. The scientists exposed Daphnia to varying levels of the pesticide pyriproxyfen, an insecticide that mimics the Mf hormone. The exposure resulted in Daphnia producing […]

(Beyond Pesticides, April 12, 2013) A study released this month on termite pesticide applications reveals that women exposed within a year of pregnancy are almost twice as likely to have a child that develops a brain tumor. Research was led by Professor Elizabeth Milne, PhD., head of the cancer epidemiology group at the Telethon Institute for Child Research. Published in Cancer Causes and Control, the article, “Exposure to Pesticides and the Risk of Childhood Brain Tumors,” studies whether exposure to pesticides a year prior to conception, during pregnancy and exposure during childhood were likely to augment the risk of brain tumors. Instead of examining household applications by homeowners, the study examines the role of pesticides applied by professional pest control applicators particularly to eradicate termites, spiders, and insects. “The findings confirm what has been found in previous studies but we have been able to go a little bit further,” Professor Milne said. Interestingly, “The increased risk associated with termite treatments may be as high as twofold, while the increased risk with other pesticides may be about 30 percent.” The study accounted for 303 cases of those that were exposed to pesticides and 941 families that were not exposed. Data came […]

(Beyond Pesticides, March 1, 2013) In a literature review published in Toxicology last week, researchers found that environmental and occupational pesticide exposure was strongly associated with declines in sperm count. Researchers Sheena Martenies, BS, and Melissa Perry, ScD., MHS., determined that of the 17 studies evaluated, 15 of them reported significant associations between pesticides and semen quality. The researchers counted semen quality according to concentration of sperm over an area, their motility and ability to move, as well as their shapes. Researchers targeted studies on DDT, HCH, and abamectin, grouping pyrethroids and organophosphates by class. What they found was striking: almost all the studies reported a decrease in sperm concentration; decreased motility was also reported though less frequently; while morphological changes were not strongly associated in studies””only two indicated any changes to sperm shape. These findings build on a growing body of evidence that pesticide exposure at environmental or occupational levels diminished sperm health. In addition to the U.S. findings,  studies conducted on French, New Zealander, Indian, Tunisian, and Israeli men have all found decline in sperm count. Some studies record a drop by approximately 50% between 1940 and 1990, no small amount. These results might not be surprising as […]

(Beyond Pesticides, February 20, 2013) A new report by the United Nations Environment Programme (UNEP) and the World Health Organization (WHO) has identified endocrine disrupting chemicals as having significant health implications for the global population. According to the report, these chemicals have the capacity to interfere with tissue and organ development and function, and therefore they may alter susceptibility to different types of diseases throughout life, and represents a global threat that needs to be resolved. The report cites insufficient reporting and information on chemicals in products, materials and goods and calls for more research and collaboration. The State of the Science of Endocrine Disrupting Chemicals,   a joint study by UNEP and WHO, finds that endocrine disrupting chemicals (EDCs) are important environmental risk factors for endocrine diseases. Exposures during critical phases of development play an important role in the onset of many diseases, affecting future generations. Trends indicate an increasing burden of certain endocrine diseases across the globe, and it is clear from human studies that populations are exposed to perhaps hundreds of environmental chemicals at any one time. This UN study, which is the most comprehensive report on EDCs to date, highlights some association between exposure to EDCs […]

(Beyond Pesticides, February 14, 2013)   Beyond Pesticides’ 31st National Pesticide Forum brings together top national scientists with local and national activists and concerned citizens to share information on the issues local communities are facing, craft solutions and catalyze networks to advance positive health and environmental policy and change. Sustainable Families, Farms and Food: Resilient communities through organic practices will be held April 5-6, 2013 at the University of New Mexico in Albuquerque, NM. For more information and to register, go to www.beyondpesticides.org/forum. The 2013 conference will focus on building resilience in our food system and bringing ecosystems back to balance, incorporating regional issues such as water and food sovereignty in the Southwest. The conference is convened by Beyond Pesticides, University of New Mexico Sustainability Studies Program (UNM SSP) and La Montanita Food Co-op.Local co-sponsors include: Agri-cultura Network, Amigos Bravos, Cuatro Puerta, Farm to Table, Food and Water Watch NM, Holistic Management International, Mid-Region Council of Governments Agriculture Collaborative, New Mexico Department of Agriculture’s Organic Program, Our Endangered Aquifer Working Group, Skarsgard Farms, South Valley Economic Development Center (SVEDC). Registration is $15 for students, $35 for activists, $75 for non-members (includes a 1-year membership) and $175 for businesses. Registration covers […]

(Beyond Pesticides, February 8, 2013) A recent study conducted at the University of Granada, Spain and published in the Journal Environmental Research proposes a link between exposure to persistent organic pollutants (POPs) in food, air, and water and prevalence of type 2 diabetes in adults, regardless of age, gender, and body mass index. The paper concludes that people with higher concentrations of DDE, the break down product of DDT, are four times more likely to develop type 2 diabetes compared to other participants in the study. Increased rates of type 2 diabetes are also associated with exposure to beta-hexachlorocyclohexane, a break down product of the toxic chemical lindane, which in still allowed for use in agriculture and certain formulations of products used to treat lice and scabies. The study was carried out by analyzing the concentrations of specific POPs in adipose, or fat, tissue of 386 adults undergoing non-cancer-related surgery in Spain. According to one of the authors of the study, Juan Pedro Arrebola, “Human adipose tissue acts as an energy reservoir and has an important metabolic function. However, adipose tissue can store potentially harmful substances, such as POPs.”    The study found that as concentrations of POPs grows in […]

(Beyond Pesticides, January 31, 2012) A new study finds that a mother’s exposure to pesticides before, during and after pregnancy may increase the risk of infant leukemia diagnosed before the age of two. Researchers in Brazil found that children are twice as likely to develop the rare cancers if their mothers were exposed three months before conception when compared to mothers who reported no exposures. A mother’s exposure at any time to the insecticide permethrin also raised the cancer risk for infants. The results support recommendations for women of reproductive age to minimize their pesticide exposure before and during pregnancy and while breastfeeding, and adds to the growing weight of evidence of the dangers of using synthetic pyrethroid pesticides. The study, entitled, “In utero pesticide exposure and leukemia in Brazilian children less than 2 years of age,” is published in Environmental Health Perspectives. Researchers asked mothers in Brazil about their pesticide exposure three months before pregnancy, while pregnant and three months after pregnancy when they were nursing. The women reported their home, work and agricultural contact with pesticides (at least once) between 1999 and 2007. Pesticide exposures from mothers of 252 children younger than two years old and diagnosed with […]

(Beyond Pesticides, January 23, 2013) A new federal report finds toxic contamination remains widespread in the Chesapeake Bay, with severe impacts in some places, which health and environmental advocates say lends support to their push in Maryland for legislative action on pesticides and other hazardous chemicals. In spite of some cleanup, the health of the Bay has not significantly improved. The report, “Technical Report on Toxic Contaminants in the Chesapeake Bay and its Watershed: Extent and Severity of Occurrence and Potential Biological Effects” is based on a review of integrated water-quality assessment reports from the jurisdictions in the Bay watershed (Delaware, Maryland, New York, Pennsylvania, Virginia, West Virginia, and Washington, D.C.), Federal and State reports, and articles in scientific journals. It notes that nearly three-fourths of the Bay’s tidal waters are “fully or partially impaired” by toxic chemicals, with people warned to limit fish consumption from certain areas. Contamination is severe in a handful of “hot spots” around the Bay, including Baltimore’s harbor, largely a legacy of past industrial and shipping activity. Previous reports have called on federal, state and local government to accelerate research into what threats chemical contamination may pose to the Bay, and to step up efforts […]